KR20220113858A - Light meal typed pet nutrient having a shape of red ginseng - Google Patents

Light meal typed pet nutrient having a shape of red ginseng Download PDF

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KR20220113858A
KR20220113858A KR1020210017131A KR20210017131A KR20220113858A KR 20220113858 A KR20220113858 A KR 20220113858A KR 1020210017131 A KR1020210017131 A KR 1020210017131A KR 20210017131 A KR20210017131 A KR 20210017131A KR 20220113858 A KR20220113858 A KR 20220113858A
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weight
parts
vitamin
jelly
powder
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KR1020210017131A
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맹승민
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맹승민
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/163—Sugars; Polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L21/00—Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
    • A23L21/10—Marmalades; Jams; Jellies; Other similar fruit or vegetable compositions; Simulated fruit products
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A23L33/165—Complexes or chelates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87—Re-use of by-products of food processing for fodder production
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S426/00—Food or edible material: processes, compositions, and products
    • Y10S426/805—Pet food for dog, cat, bird, or fish

Abstract

The present invention provides jelly-shaped snack-type herbal nutritional supplements for pets containing gelatin, medicinal ingredients, and complex vitamins. According to the present invention, by using gelatin as a base material, the texture is excellent, and by adding the medicinal ingredients and the complex vitamins to enhance immune activity, it is possible to prevent various diseases in advance.

Description

젤리 형상의 간식형 반려동물 한방 영양제{LIGHT MEAL TYPED PET NUTRIENT HAVING A SHAPE OF RED GINSENG}Jelly-shaped snack-type herbal supplement for companion animals {LIGHT MEAL TYPED PET NUTRIENT HAVING A SHAPE OF RED GINSENG}

본 발명은 반려동물 영양제에 관한 것으로, 보다 상세하게는 기재로 젤라틴을 이용하여 식감이 우수하고 약용성분 및 복합비타민을 첨가하여 각종 질병에 미리 예방할 수 있도록 하고, 홍삼형상으로 성형함으로써 제품의 시각적인 특성을 개선하여 부가가치를 높인 젤리 형상의 간식형 반려동물 한방 영양제에 관한 것이다.The present invention relates to a nutritional supplement for companion animals, and more particularly, it uses gelatin as a base material to provide excellent texture, add medicinal ingredients and complex vitamins to prevent various diseases in advance, and shape the product into a red ginseng shape. It relates to a jelly-shaped snack-type oriental herbal supplement for companion animals that has improved properties and increased added value.

일반적으로 반려동물 들을 포함한 모든 동물들은 각각의 본능이나 독특한 습성이 있으며, 이중에서 예를 들어 가장 많이 키우고 있는 반려견의 경우, 유치가 나기 시작하면서 뭐든지 물어뜯는 본능을 표출한다.In general, all animals, including companion animals, have their own instincts and unique habits, and among them, for example, in the case of the most domesticated dog, when the baby teeth begin to appear, they express the instinct to bite anything.

이와 같은 반려동물의 습성욕구를 해소시키기 위하여 반려동물용 껌이 제작되어 사용되고 있는데, 통상적인 반려동물용 껌은 소가죽이나 돼지가죽과 같은 동물가죽을 가공하거나, 슬러지와 소정의 향을 조성한 후 뼈 모양이나 막대 모양으로 성형하여 제조하고 있다.In order to solve the habitual needs of companion animals, gum for companion animals has been produced and used. In general, gum for companion animals is produced by processing animal skins such as cowhide or pigskin, or after forming sludge and a predetermined flavor with bone. It is manufactured by molding into a shape or a rod shape.

이러한 반려동물용 껌은 비교적 단단하여 쉽게 먹을 수 없고, 계속 물어뜯을 수 있기 때문에 반려동물의 습성욕구를 해소하면서, 아울러 껌을 씹을 때 마찰로 인하여 치석을 제거하거나 치석제거성분이 생겨나기도 하여 치아건강에 유익하다고 알려져 있다.These gums for companion animals are relatively hard, so they cannot be easily eaten, and can be bitten continuously, so they satisfy the pet's habitual desires. known to be beneficial to

이러한 반려동물용 껌은 반려동물들의 물어뜯는 습성욕구를 해소시키는 점에서는 유용하지만, 식감과 맛이 지나치게 떨어져 쉽게 싫증을 내기 쉽고, 더욱이 면역력, 관절, 피부와 모발, 체중, 내지 정신건강의 조절 내지 증대기능과 같은 각종 기능성 개선 및 영양개선 효과는 현재까지의 기술로는 기대하기 곤란한 실정이다.These chewing gums for companion animals are useful in relieving companion animals' desire for biting, but the texture and taste are too low, so they are easy to get bored easily, and furthermore, they control immunity, joints, skin and hair, weight, and mental health. Various functional improvement and nutritional improvement effects such as augmentation function are difficult to expect with the current technology.

[선행기술문헌][Prior art literature]

등록실용 제20-0384299No. 20-0384299 for registration room

본 발명은 상기한 바와 같은 종래기술이 가지는 문제를 해결하기 위해 안출된 것으로, 그 목적은 기재로 젤라틴을 이용하여 식감이 우수하고 약용성분 및 복합비타민을 첨가하여 면역활성을 증진하여 각종 질병에 미리 예방할 수 있도록 하고, 홍삼형상으로 성형함으로써 제품의 시각적인 특성을 개선하여 부가가치를 높인 간식형 반려동물 영양제를 제공함에 있다.The present invention has been devised to solve the problems of the prior art as described above, and its purpose is to use gelatin as a base material to have excellent texture and to enhance immune activity by adding medicinal ingredients and complex vitamins to prevent various diseases in advance. It aims to provide a snack-type companion animal nutrition supplement that increases added value by improving the visual characteristics of the product by making it possible to prevent it and molding it in the shape of red ginseng.

상기한 바와 같은 본 발명의 기술적 과제는 다음과 같은 수단에 의해 달성되어진다.The technical problem of the present invention as described above is achieved by the following means.

(1) 젤라틴 및 복합비타민을 함유하는 젤리 형상의 간식형 반려동물 한방 영양제.(1) Jelly-shaped snack-type oriental herbal supplement containing gelatin and complex vitamins.

(2) 상기 (1)에 있어서,(2) in (1) above,

젤라틴, 약용성분, 및 복합비타민을 함유하는 용액과 부형제를 혼합하고, 상기 혼합물을 홍삼형상으로 성형하여 건조한 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제. A jelly-shaped snack-type oriental herbal nutritional supplement for companion animals, characterized in that a solution containing gelatin, medicinal ingredients, and complex vitamins and excipients are mixed, and the mixture is molded into a red ginseng shape and dried.

(3) 상기 (2)에 있어서,(3) in (2) above,

약용성분은 하수오, 구기자, 복분자, 황기 및 숙지황 분말인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제. A jelly-shaped snack-type oriental herbal nutritional supplement for companion animals, characterized in that the medicinal ingredients are succulents, goji berries, bokbunja, astragalus, and sukjihwang powder.

(4) 상기 (2)에 있어서,(4) in (2) above,

약용성분은 홍화씨, 가시오가피, 우슬, 독활, 두충 및 창출 분말인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제.The medicinal ingredients are safflower seeds, spiny hornworts, hyssop, poison ivy, duchung, and jellied powder.

(5) 상기 (2)에 있어서,(5) in (2) above,

약용성분은 산사, 후박, 백출, 맥아, 진피 및 유근피 분말인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제.A jelly-shaped snack-type oriental herbal supplement for companion animals, characterized in that the medicinal ingredients are hawthorn, squash, baekchul, malt, dermis, and eugeunpi powder.

(6) 상기 (2)에 있어서,(6) in (2) above,

약용성분은 어성초, 아마씨, 산수유, 백봉령, 산약 및 흑임자 분말인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제.A jelly-shaped snack-type oriental herbal supplement for companion animals, characterized in that the medicinal ingredients are eoseongcho, flaxseed, cornflower oil, baekbongryeong, sanyak, and black sesame powder.

(7) 상기 (2)에 있어서,(7) in (2) above,

약용성분은 함초, 차전자, 삼백초, 길경 치커리, 및 의이인 분말인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제.Medicinal ingredients are green tea, green tea, ginseng, gilgyeong chicory, and uiiin powder.

(8) 상기 (2)에 있어서,(8) in (2) above,

약용성분은 연잎, 맥문동, 죽여, 연자육, 석창포 및 작약 분말인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제.Medicinal ingredients include lotus leaf, maekmundong, porridge, lotus root meat, seokchangpo and peony powder.

(9) 상기 (1)에 있어서,(9) in (1) above,

복합비타민은 비타민 A, 비타민 D3, 비타민 E, 비타민 B1, 비타민 B2, 비타민 B6, 비타민 C, 비타민 D3, 비타민 K3, 나이아신아미드, 엽산, 판토텐산칼슘, DL-메티오닌을 포함하는 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제. Multivitamin is a jelly-like, characterized in that it contains vitamin A, vitamin D3, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin C, vitamin D3, vitamin K3, niacinamide, folic acid, calcium pantothenate, DL-methionine A snack-type herbal supplement for pets.

(10) 상기 (1)에 있어서,(10) in (1) above,

6년근 고려홍삼, 글루코사민, 알로에 아보레센스, 오메가3, 가르시아 캄보지아 추출물(HCA) 및 가바(GABA)의 군에서 선택된 적어도 1종을 더 포함하는 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제.6-year-old Korean red ginseng, glucosamine, aloe arborescens, omega 3, garcia cambogia extract (HCA) and GABA (GABA), characterized in that it further comprises at least one selected from the group of jelly-shaped snack-type companion animal oriental herbal nutritional supplement.

상기와 같이 본 발명에 의하면, 기재로 젤라틴을 이용하여 식감이 우수하고 약용성분 및 복합비타민을 첨가하여 면역활성을 증진하여 각종 질병에 미리 예방할 수 있도록 하고, 홍삼형상으로 성형함으로써 제품의 시각적인 특성을 개선하여 부가가치를 높인 간식형 영양제를 제공한다.As described above, according to the present invention, by using gelatin as a base material, the texture is excellent, and by adding medicinal ingredients and multivitamins to enhance immune activity to prevent various diseases in advance, and by molding into a red ginseng shape, the visual characteristics of the product Provide snack-type nutritional supplements with increased added value by improving

도 1은 본 발명에 따른 젤리 형상의 간식형 반려동물 한방 영양제의 제조공정도.1 is a manufacturing process diagram of a jelly-shaped snack-type companion animal oriental nutritional supplement according to the present invention.

본 발명에 따른 젤리 형상의 간식형 반려동물 한방 영양제는 젤라틴 및 복합비타민을 함유한다.The jelly-shaped snack-type oriental herbal supplement for companion animals according to the present invention contains gelatin and complex vitamins.

본 발명에서 반려동물이라 함은 개, 고양이, 원숭이, 새 등과 같은 애완동물이나 돼지, 소, 닭 등과 같은 축산동물, 및 기타 양식어류를 포함한다.In the present invention, the term companion animal includes pets such as dogs, cats, monkeys, birds, etc., livestock animals such as pigs, cattle, chickens, etc., and other farmed fish.

본 발명에 따른 젤리 형상의 간식형 반려동물 한방 영양제는 제1실시예로써, 젤라틴 용액 60~65 중량%에, 복합비타민 100 중량부에 대하여 그 구성비가 비타민 A 0.2~0.3 중량부, 비타민 D3 0.05~0.06 중량부, 비타민 E 8.0~8.5 중량부, 비타민 B1 4.0~4.5 중량부, 비타민 B2 12.0~13.0 중량부, 비타민 B6 4.0~4.5 중량부, 비타민 C 8.0~8.5 중량부, 비타민 K3 1.0~1.5 중량부, 나이아신아미드 13.0~14.0 중량부, 엽산 0.2~0.3 중량부, 판토텐산칼슘 8.0~8.5 중량부, DL-메티오닌 33.0~34.0 중량부 및 카르니틴 5.0~6.0 중량부인 복합비타민 1~2 중량%, 및 잔량의 기타 첨가제를 포함한다.The jelly-shaped snack-type oriental herbal supplement for companion animals according to the present invention is a first embodiment, and the composition ratio is 0.2 to 0.3 parts by weight of vitamin A, and 0.05 parts by weight of vitamin D3 based on 100 parts by weight of multivitamin in 60 to 65% by weight of gelatin solution. ~0.06 parts by weight, vitamin E 8.0 to 8.5 parts by weight, vitamin B1 4.0 to 4.5 parts by weight, vitamin B2 12.0-13.0 parts by weight, vitamin B6 4.0 to 4.5 parts by weight, vitamin C 8.0 to 8.5 parts by weight, vitamin K3 1.0 to 1.5 Parts by weight, niacinamide 13.0 to 14.0 parts by weight, folic acid 0.2 to 0.3 parts by weight, calcium pantothenate 8.0 to 8.5 parts by weight, DL-methionine 33.0 to 34.0 parts by weight, and carnitine 5.0 to 6.0 parts by weight of multivitamin 1 to 2% by weight, and and the remainder of other additives.

상기 본 발명의 제1실시예에 따른 간식형 반려동물 영양제는 특히 각종 질병에 대한 면역력을 개선시켜 주는 기능을 제공하기에 적합한 제형이다.The snack-type companion animal nutritional supplement according to the first embodiment of the present invention is particularly suitable for providing a function of improving immunity against various diseases.

본 발명은 바람직하게는 상기 젤라틴 및 복합비타민 성분 이외에 한방성분으로 구성되는 약용성분을 더 포함한다.The present invention preferably further comprises a medicinal component composed of an oriental medicine component in addition to the gelatin and multivitamin component.

이에 따라, 본 발명에 따른 젤리 형상의 간식형 반려동물 한방 영양제는 제2실시예로써, 상기 젤라틴 용액 및 복합비타민에 더하여 약용성분으로 하수오, 구기자, 복분자, 황기 및 숙지황 분말을 각각 0.1~1.0 중량% 첨가한다. Accordingly, the jelly-shaped snack-type oriental herbal supplement for companion animals according to the present invention is a second embodiment, and in addition to the gelatin solution and multivitamin, as medicinal ingredients, 0.1 to 1.0 weight each of S. % is added.

상기 본 발명의 제2실시예에 따른 간식형 반려동물 영양제는 특히 각종 질병에 대한 면역력을 보다 개선시켜 주는 기능을 제공하기에 적합한 제형으로, 이러한 기능성을 보강하기 위하여 6년근 고려홍삼 분말을 더 포함하는 것이 바람직하다. 상기 6년근 고려홍삼 분말은 0.1~1.0 중량% 첨가한다.The snack-type companion animal nutritional supplement according to the second embodiment of the present invention is a formulation suitable for providing a function that improves immunity to various diseases, and further contains 6-year-old Korean red ginseng powder to reinforce this function. It is preferable to do The 6-year-old Korean red ginseng powder is added in an amount of 0.1 to 1.0% by weight.

본 발명에 따른 젤리 형상의 간식형 반려동물 한방 영양제는 제3실시예로써, 상기 젤라틴 용액 및 복합비타민에 더하여 약용성분으로 홍화씨, 가시오가피, 우슬, 독활, 두충 및 창출 분말을 각각 0.1~1.0 중량% 첨가한다.The jelly-shaped snack-type oriental herbal supplement for companion animals according to the present invention is a third embodiment, and in addition to the gelatin solution and multivitamin, safflower seed, spiny hornwort, hyssop, poison ivy, cephalosporus and safflower powder are each 0.1 to 1.0% by weight as medicinal ingredients. add

상기 본 발명의 제3실시예에 따른 간식형 반려동물 영양제는 면역증강활성 외에 특히 관절기능의 개선을 위해 적합한 제형으로, 이러한 기능성을 보강하기 위하여 글루코사민 분말을 더 포함하는 것이 바람직하다. 상기 글루코사민 분말은 0.1~1.0 중량% 첨가한다.The snack-type companion animal nutritional supplement according to the third embodiment of the present invention is a formulation suitable for improving joint function in addition to immune enhancing activity, and it is preferable to further include glucosamine powder to reinforce this function. The glucosamine powder is added in an amount of 0.1 to 1.0% by weight.

본 발명에 따른 젤리 형상의 간식형 반려동물 한방 영양제는 제4실시예로써, 상기 젤라틴 용액 및 복합비타민에 더하여 약용성분으로 산사, 후박, 백출, 맥아, 진피 및 유근피 분말을 각각 0.1~1.0 중량% 첨가한다.Jelly-shaped snack-type oriental herbal supplement for companion animals according to the present invention is a fourth embodiment, and in addition to the gelatin solution and multivitamin, hawthorn, hawthorn, baekchul, malt, dermis and eugeunpi powder as medicinal ingredients in an amount of 0.1 to 1.0% by weight, respectively. add

상기 본 발명의 제4실시예에 따른 간식형 반려동물 영양제는 면역증강활성 외에 특히 장의 기능개선을 위해 적합한 제형으로, 이러한 기능성을 보강하기 위하여 알로에 아보레센스 분말을 더 포함하는 것이 바람직하다. 상기 알로에 아보레센스 분말은 0.1~1.0 중량% 첨가한다.The snack-type companion animal nutritional supplement according to the fourth embodiment of the present invention is a formulation suitable for improving intestinal function in addition to immune enhancing activity, and it is preferable to further include aloe aborescens powder to reinforce this function. The aloe arborescens powder is added in an amount of 0.1 to 1.0% by weight.

본 발명에 따른 젤리 형상의 간식형 반려동물 한방 영양제는 제5실시예로써, 상기 젤라틴 용액 및 복합비타민에 더하여 약용성분으로 어성초, 아마씨, 산수유, 백봉령, 산약, 및 흑임자 분말을 각각 0.1~1.0 중량% 첨가한다.A jelly-shaped snack-type oriental herbal supplement for companion animals according to the present invention is a fifth embodiment, and in addition to the gelatin solution and multivitamin, 0.1 to 1.0 weight each of eoseongcho, flaxseed, cornflower oil, baekbongryeong, sanyak, and black sesame powder as medicinal ingredients % is added.

상기 본 발명의 제5실시예에 따른 간식형 반려동물 영양제는 면역증강활성 외에 피부와 모(毛)의 개선을 위해 적합한 제형으로, 이러한 기능성을 보강하기 위하여 오메가 3 분말을 더 포함하는 것이 바람직하다. 상기 오메가 3분말은 0.1~1.0 중량% 첨가한다.The snack-type companion animal nutritional supplement according to the fifth embodiment of the present invention is a formulation suitable for skin and hair improvement in addition to immune enhancing activity, and it is preferable to further include omega 3 powder to reinforce this functionality. . The omega 3 powder is added in an amount of 0.1 to 1.0% by weight.

본 발명에 따른 젤리 형상의 간식형 반려동물 한방 영양제는 제6실시예로써, 상기 젤라틴 용액 및 복합비타민에 더하여 약용성분으로 함초, 차전자, 삼백초, 길경, 치커리, 및 의이인 분말을 각각 0.1~1.0 중량% 첨가한다.The jelly-shaped snack-type oriental herbal supplement for companion animals according to the present invention is a sixth embodiment, and in addition to the gelatin solution and multivitamin, green tea, psyllium, three hundred seconds, gilkyung, chicory, and uiiin powder as medicinal ingredients 0.1 to 1.0, respectively. % by weight is added.

상기 본 발명의 제6실시예에 따른 간식형 반려동물 영양제는 면역증강활성 외에 특히 체중조절 기능을 제공하기에 적합한 제형으로, 이러한 기능성을 보강하기 위하여 가르시니아 캄보지아(HCA) 분말을 더 포함하는 것이 바람직하다. 상기 가르시니아 캄보지아(HCA) 분말은 0.1~1.0 중량% 첨가한다.The snack-type companion animal nutritional supplement according to the sixth embodiment of the present invention is a formulation suitable for providing a weight control function in addition to immune enhancing activity, and it is preferable to further include garcinia cambogia (HCA) powder to reinforce this function. do. The garcinia cambogia (HCA) powder is added in an amount of 0.1 to 1.0% by weight.

본 발명에 따른 젤리 형상의 간식형 반려동물 한방 영양제는 제7실시예로써, 상기 젤라틴 용액 및 복합비타민에 더하여 약용성분으로 연잎, 맥문동, 죽여, 연자육, 석창포 및 작약 분말을 각각 0.1~1.0 중량% 첨가한다.The jelly-shaped snack-type oriental herbal supplement for companion animals according to the present invention is a seventh embodiment, and in addition to the gelatin solution and multivitamin, lotus leaf, maekmundong, porridge, lotus leaf, maekmundong, porridge, lotus leaf, seokchangpo and peony powder are each 0.1 to 1.0% by weight. add

상기 본 발명의 제7실시예에 따른 간식형 반려동물 영양제는 면역증강활성 외에 특히 정신건강의 개선을 위해 적합한 제형으로, 이러한 기능성을 보강하기 위하여 가바(GABA) 분말을 더 포함하는 것이 바람직하다. 상기 가바(GABA) 분말은 0.1~1.0 중량% 첨가한다.The snack-type companion animal nutritional supplement according to the seventh embodiment of the present invention is a formulation suitable for improving mental health in addition to immune enhancing activity, and it is preferable to further include GABA powder to reinforce this functionality. The GABA powder is added in an amount of 0.1 to 1.0% by weight.

위와 같이 본 발명의 각 실시예에 따라 각각 조성된 혼합물에 당류(글리세린, 덱스트린 등), 향미제, 천연색소, 정제수 등을 잔량으로 첨가한 후, 6년근 홍삼형상의 상부 및 하부 형틀에 주입하여 성형한 후, 건조하면 6년근 젤리 형상의 간식형 반려동물 한방 영양제를 제조할 수 있다.As above, sugar (glycerin, dextrin, etc.), flavoring agent, natural colorant, purified water, etc. are added to the mixture prepared according to each embodiment of the present invention as above, and then injected into the upper and lower molds of 6-year-old red ginseng shape. After molding and drying, it is possible to manufacture a 6-year-old jelly-shaped snack-type oriental herbal supplement for companion animals.

상기와 같은 젤리 형상의 간식형 반려동물 한방 영양제는 반려동물들의 물어뜯는 습성욕구를 충족시켜주면서, 식감이 우수하고 여기에 약용성분 및 복합비타민을 첨가하여 각종 기능성 개선 내지 질병 예방에 탁월한 효과를 제공하며, 특히 6년근 홍삼형상으로 성형함으로써 제품의 시각적인 특성을 개선하여 부가가치를 높인 특징이 있다.The above-mentioned jelly-shaped snack-type oriental herbal supplement for companion animals satisfies the pets' desire for biting habits, has an excellent texture, and by adding medicinal ingredients and complex vitamins to it, provides excellent effects in improving various functions and preventing diseases. In particular, it has the characteristic of increasing added value by improving the visual characteristics of the product by molding it in the shape of 6-year-old red ginseng.

이하 본 발명의 내용을 실시예 내지 실험예를 참조하여 보다 상세하게 설명하고자 한다. 다만 하기 예시된 실시예 등은 본 발명의 이해를 돕기 위해 제시되는 것일 뿐 이에 의해 본 발명의 권리범위가 한정되는 것으로 해석되어서는 아니된다.Hereinafter, the contents of the present invention will be described in more detail with reference to Examples or Experimental Examples. However, the following examples and the like are only presented to help the understanding of the present invention and should not be construed as limiting the scope of the present invention.

[실시예 1] 영양제의 제조[Example 1] Preparation of nutritional supplements

도 1에 기재된 방법에 따라 표 1에 나타낸 바와 같이 젤라틴, 복합비타민, 및 기타 첨가제를 조성비에 따라 혼합하였다. 이때 복합비타민의 조성은 복합비타민의 중량대비 비타민 A 0.27 중량%, 비타민 D3 0.05 중량%, 비타민 E 8.3 중량%, 비타민 B1 4.2 중량%, 비타민 B2 12.5 중량%, 비타민 B6 4.2 중량%, 비타민 C 8.3 중량%, 비타민 K3 1.1 중량%, 나이아신아미드 13.8 중량%, 엽산 0.27 중량%, 판토텐산칼슘 8.3 중량%, DL-메티오닌 33.11 중량% 및 카르니틴 5.6 중량%로 조성하였다.According to the method described in FIG. 1, as shown in Table 1, gelatin, multivitamin, and other additives were mixed according to the composition ratio. At this time, the composition of the multivitamin is vitamin A 0.27% by weight, vitamin D3 0.05% by weight, vitamin E 8.3% by weight, vitamin B1 4.2% by weight, vitamin B2 12.5% by weight, vitamin B6 4.2% by weight, vitamin C 8.3 compared to the weight of the multivitamin % by weight, vitamin K3 1.1% by weight, niacinamide 13.8% by weight, folic acid 0.27% by weight, calcium pantothenate 8.3% by weight, DL-methionine 33.11% by weight, and carnitine 5.6% by weight.

위와 같이 조성된 혼합물을 6년근 홍삼형틀 내에 주입하고 성형한 후 건조하였다.The mixture prepared as above was injected into a 6-year-old red ginseng mold, molded, and dried.

NoNo 원 료 명Raw material name 비율(중량%) Ratio (wt%) 1One 복합비타민multivitamin 2.0 2.0 22 젤라틴gelatin 65.0 65.0 33 글리세린glycerin 26.0 26.0 44 덱스트린dextrin 5.0 5.0 55 향미제flavoring agent 1.0 1.0 66 천연색소natural pigment 1.0 1.0

[실시예 2] 영양제의 제조도 1에 기재된 방법에 따라 표 2에 나타낸 바와 같이 젤라틴, 복합비타민 및 기타 첨가물 외에 하수오, 구기자, 복분자, 황기 및 숙지황 분말을 각각 첨가하였다. 위와 같이 조성된 혼합물을 6년근 홍삼형틀 내에 주입하고 성형한 후 건조하였다.[Example 2] Preparation of nutritional supplements As shown in Table 2 according to the method described in FIG. 1, in addition to gelatin, multivitamin and other additives, succulents, Goji berry, bokbunja, Astragalus and Sukjihwang powder were added, respectively. The mixture prepared as above was injected into a 6-year-old red ginseng mold, molded, and dried.

NoNo 원 료 명Raw material name 비율(중량%) Ratio (wt%) 1One 복합비타민multivitamin 2.0 2.0 22 젤라틴gelatin 63.0 63.0 33 글리세린glycerin 25.0 25.0 44 덱스트린dextrin 5.0 5.0 55 향미제flavoring agent 1.0 1.0 66 천연색소natural pigment 1.0 1.0 77 6년근 홍삼6-year-old red ginseng 0.5 0.5 88 하수오Ha Soo Oh 0.5 0.5 99 구기자Goji berries 0.5 0.5 1010 복분자Bokbunja 0.5 0.5 1111 황기Astragalus 0.5 0.5 1212 숙지황Suk Sook-hwang 0.5 0.5

[실시예 3] 영양제의 제조도 1에 기재된 방법에 따라 표 3에 나타낸 바와 같이 젤라틴, 복합비타민 및 기타 첨가물 외에 홍화씨, 가시오가피, 우슬, 독활, 두충 및 창출 분말을 각각 첨가하였다. 위와 같이 조성된 혼합물을 6년근 홍삼형틀 내에 주입하고 성형한 후 건조하였다.[Example 3] Preparation of nutrient According to the method described in FIG. 1, as shown in Table 3, safflower seeds, spiny hornwort, hyssop, Tokhwal, Duchung and Chrysanthemum powder were added in addition to gelatin, multivitamin and other additives, respectively. The mixture prepared as above was injected into a 6-year-old red ginseng mold, molded, and dried.

NoNo 원 료 명Raw material name 비율(중량%) Ratio (wt%) 1One 비타민믹스vitamin mix 2.0 2.0 22 젤라틴gelatin 62.5 62.5 33 글리세린glycerin 25.0 25.0 44 덱스트린dextrin 5.0 5.0 55 향미제flavoring agent 1.0 1.0 66 천연색소natural pigment 1.0 1.0 77 글루코사민glucosamine 0.5 0.5 88 홍화씨Mr. Hong 0.5 0.5 99 가시오가피spiny 0.5 0.5 1010 우슬hyssop 0.5 0.5 1111 독활solitary 0.5 0.5 1212 두충headworm 0.5 0.5 1313 창출Creation 0.5 0.5

[실시예 4] 영양제의 제조도 1에 기재된 방법에 따라 표 4에 나타낸 바와 같이 젤라틴, 복합비타민 및 기타 첨가물 외에 산사, 후박, 백출, 맥아, 진피 및 유근피 분말을 각각 첨가하였다. 위와 같이 조성된 혼합물을 6년근 홍삼형틀 내에 주입하고 성형한 후 건조하였다.[Example 4] Preparation of nutritional supplements As shown in Table 4 according to the method described in Fig. 1, hawthorn, hubark, baekchul, malt, dermis and eugeunpi powder were added in addition to gelatin, multivitamin and other additives, respectively. The mixture prepared as above was injected into a 6-year-old red ginseng mold, molded, and dried.

NoNo 원 료 명Raw material name 비율(중량%) Ratio (wt%) 1One 비타민믹스vitamin mix 2.0 2.0 22 젤라틴gelatin 62.5 62.5 33 글리세린glycerin 25.0 25.0 44 덱스트린dextrin 5.0 5.0 55 향미제flavoring agent 1.0 1.0 66 천연색소natural pigment 1.0 1.0 77 알로에 아보레센스분말aloe vera extract powder 0.5 0.5 88 산사sansa 0.5 0.5 99 후박humpback 0.5 0.5 1010 백출Baekchul 0.5 0.5 1111 맥아malt 0.5 0.5 1212 진피dermis 0.5 0.5 1313 유근피You Geun-Pi 0.5 0.5

[실시예 5] 영양제의 제조도 1에 기재된 방법에 따라 표 5에 나타낸 바와 같이 젤라틴, 복합비타민 및 기타 첨가물 외에 어성초, 아마씨, 산수유, 백봉령, 산약, 및 흑임자 분말을 각각 첨가하였다. 위와 같이 조성된 혼합물을 6년근 홍삼형틀 내에 주입하고 성형한 후 건조하였다.[Example 5] Preparation of nutritional supplements As shown in Table 5 according to the method described in FIG. 1, eoseongcho, flaxseed, cornflower oil, baekbongryeong, sanyak, and black sesame powder were added in addition to gelatin, multivitamin and other additives, respectively. The mixture prepared as above was injected into a 6-year-old red ginseng mold, molded, and dried.

NoNo 원 료 명Raw material name 비율(중량%) Ratio (wt%) 1One 비타민믹스vitamin mix 2.0 2.0 22 젤라틴gelatin 62.5 62.5 33 글리세린glycerin 25.0 25.0 44 덱스트린dextrin 5.0 5.0 55 향미제flavoring agent 1.0 1.0 66 천연색소natural pigment 1.0 1.0 77 오메가3Omega 3 0.5 0.5 88 어성초Eoseongcho 0.5 0.5 99 아마씨flaxseed 0.5 0.5 1010 산수유corn milk 0.5 0.5 1111 백복령Baek Bok-ryeong 0.5 0.5 1212 산약acid pill 0.5 0.5 1313 흑임자black sesame 0.5 0.5

[실시예 6] 영양제의 제조도 1에 기재된 방법에 따라 표 6에 나타낸 바와 같이 젤라틴, 복합비타민 및 기타 첨가물 외에 함초, 차전자, 삼백초, 길경, 치커리, 및 의이인 분말을 각각 첨가하였다. 위와 같이 조성된 혼합물을 6년근 홍삼형틀 내에 주입하고 성형한 후 건조하였다.[Example 6] Preparation of nutritional supplements As shown in Table 6 according to the method described in FIG. 1, green tea, psyllium, sambaekcho, gilkyung, chicory, and uiiin powder were added in addition to gelatin, multivitamin and other additives, respectively. The mixture prepared as above was injected into a 6-year-old red ginseng mold, molded, and dried.

NoNo 원 료 명Raw material name 비율(중량%) Ratio (wt%) 1One 비타민믹스vitamin mix 2.0 2.0 22 젤라틴gelatin 62.5 62.5 33 글리세린glycerin 25.0 25.0 44 덱스트린dextrin 5.0 5.0 55 향미제flavoring agent 1.0 1.0 66 천연색소natural pigment 1.0 1.0 77 가르시아 캄보지아(HCA60%)Garcia Cambogia (HCA 60%) 0.5 0.5 88 함초green tea 0.5 0.5 99 차전자car electronics 0.5 0.5 1010 삼백초three hundred seconds 0.5 0.5 1111 길경Gilkyung 0.5 0.5 1212 치커리chicory 0.5 0.5 1313 의이인righteous person 0.5 0.5

[실시예 7] 영양제의 제조도 1에 기재된 방법에 따라 표 7에 나타낸 바와 같이 젤라틴, 복합비타민 및 기타 첨가물 외에 연잎, 맥문동, 죽여, 연자육, 석창포 및 작약 분말을 각각 첨가하였다. 위와 같이 조성된 혼합물을 6년근 홍삼형틀 내에 주입하고 성형한 후 건조하였다.[Example 7] Preparation of nutritional supplements As shown in Table 7 according to the method described in FIG. 1, lotus leaf, maekmundong, porridge, yeonjayuk, seokchangpo and peony powder were added in addition to gelatin, multivitamin and other additives, respectively. The mixture prepared as above was injected into a 6-year-old red ginseng mold, molded, and dried.

NoNo 원 료 명Raw material name 비율(중량%) Ratio (wt%) 1One 비타민믹스vitamin mix 2.0 2.0 22 젤라틴gelatin 62.5 62.5 33 글리세린glycerin 25.0 25.0 44 덱스트린dextrin 5.0 5.0 55 향미제flavoring agent 1.0 1.0 66 천연색소natural pigment 1.0 1.0 77 가바(GABA)GABA 0.5 0.5 88 연잎lotus leaf 0.5 0.5 99 맥문동Maekmun-dong 0.5 0.5 1010 죽여kill 0.5 0.5 1111 연자육soft meat 0.5 0.5 1212 석창포Seokchangpo 0.5 0.5 1313 작약peony 0.5 0.5

[실험예] 실시예 1 내지 7의 영양제를 각 농도별로 3차 증류수에 용해하여 조제하였으며, 랫트 110마리(암컷 6주령)를 체중 대비 무작위로 표 8과 같이 군 분리한 다음 주사기(녹십자 의료공업(주) 및 랫트용 존데를 이용하여 투여 전의 체중을 기준으로 각 영양제를 용량별로 ㎏당 10㎖를 경구로 1일 1회, 주 5회, 4주간 투여하였다. [Experimental Example] The nutrients of Examples 1 to 7 were prepared by dissolving them in tertiary distilled water for each concentration, and 110 rats (6 weeks old) were randomly grouped as shown in Table 8 by weight, and then syringes (Green Cross Medical Industry) (Note) and using a sonde for rats, 10 ml per kg of each nutrient was orally administered once a day, 5 times a week, and 4 weeks based on the body weight before administration.

시험군의 구성Composition of the test group 군army 성별gender 동물수number of animals 투여량Dosage 대조군control FemaleFemale 55 0g/㎏/day0g/kg/day 저용량 투여군low dose group FemaleFemale 5×75×7 0.24g/㎏/day0.24 g/kg/day 중간용량 투여군Intermediate dose group FemaleFemale 5×75×7 1g/㎏/day1g/kg/day 고용량 투여군high dose group FemaleFemale 5×75×7 2g/㎏/day2g/kg/day

[실험예 1] 임상변화 관찰 및 체중변화실험방법 [Experimental Example 1] Clinical change observation and weight change test method

1) 일반 증상 관찰 : 시험 기간 중에 1일 1회 일정한 시간에 실시하였다. 투여 전 및 투여 후 적어도 1주일에 1회는 구체적인 임상 증상을 전 동물에 대해 관찰하고 기록하였다. 항목으로는 동물의 건강 상태, 사망 동물, 피부, 피모, 안구, 점막의 변화, 분비 및 배설 상태, lacrimation, piloerection, 동공의 크기, 불규칙한 호흡, 보행 상태, 자세, 반응 변화에 따라 그 정도 등을 기록하였다.1) Observation of general symptoms: It was conducted at a fixed time once a day during the test period. Specific clinical symptoms were observed and recorded for all animals before dosing and at least once a week after dosing. Items include animal health status, dead animals, changes in skin, coat, eyes, mucous membranes, secretion and excretion status, lacrimation, piloerection, pupil size, irregular respiration, gait status, posture, and reaction changes. recorded.

2) 감각 신경 관찰 : 투여 후 넷째 주초기에 각 형태(청각, 시각, 주광성 등)의 자극 및 grip strength, motor activity에 대한 변화를 관찰하여 기록하였다. 2) Sensory nerve observation: At the beginning of the fourth week after administration, the stimulation of each type (auditory, visual, photoluminescent, etc.) and changes in grip strength and motor activity were observed and recorded.

3) 체중, 사료 및 음수 섭취량 측정 : 모든 동물에 대하여 투여 개시 전, 투여 개시 후, 시험 종료 시까지 매주 1회 이상 측정하였다.3) Measurement of body weight, feed and drinking water intake: All animals were measured at least once a week before administration, after administration, and until the end of the test.

실험결과Experiment result

1) 저용량(0.24g/㎏/day), 중간용량(1g/㎏/day), 고용량(2g/㎏/day) 투여군 및 대조군에서 전 기간 동안 시험 물질의 투여로 인한 임상 증상은 관찰되지 않았다.1) In the low dose (0.24g/kg/day), medium dose (1g/kg/day), high dose (2g/kg/day) administration group and the control group, no clinical symptoms were observed due to the administration of the test substance during the entire period.

2) 사망률: 시험 기간 중 사망한 개체는 없었다.2) Mortality: No subjects died during the trial period.

3) 체중 변화: 4주간 반복투여독성시험을 진행하는 동안 대조군 및 투여군 모두에서 시험물질에 의한 유의할 만한 체중 변화는 관찰되지 않았다. 3) Change in body weight: During the repeated-dose toxicity test for 4 weeks, no significant change in body weight by the test substance was observed in both the control group and the administration group.

4) 사료 및 음수 섭취량 변화: 전 시험기간을 통해 동물 당 일일 사료 및 음수섭취량은 대조군 및 시험물질 투여군에서 유의적인 차이를 나타내지 않았다. 4) Changes in feed and drinking water intake: The daily feed and drinking water intake per animal throughout the entire test period did not show a significant difference between the control group and the test substance administration group.

5) 안검사: 대조군 및 투여군 모두에서 유의할 만한 이상을 나타내지 않았다.5) Ophthalmic examination: There were no significant abnormalities in both the control group and the administration group.

[실험예 2] 면역활성 증진효과 평가(대식세포 기능 활성 평가)[Experimental Example 2] Immune activity enhancement effect evaluation (macrophage functional activity evaluation)

실험방법Experimental method

1) Raw 264.7 세포 배양 : Raw 264.7 대식세포주는 10 % FCS, 40mM 글루타민, 스트렙토마이신 및 페니실린(100 ㎍/100 U), 그리고 0.37 %의 CaCO3을 함유한 DMEM배지에서 계대 배양하여 사용하였다.1) Raw 264.7 cell culture: Raw 264.7 macrophage cell line was subcultured in DMEM medium containing 10% FCS, 40mM glutamine, streptomycin and penicillin (100 μg/100 U), and 0.37% CaCO 3 It was used.

2) 일산화질소(NO) 측정 : NO 분석은 CAYMAN(Denver, CO, USA)의 NO 키트를 사용하였다. Raw 264.7 세포를 96 웰플레이트에 1×105 cells/ml로 분주한 후에 24시간 동안 배양시킨 다음, Raw 264.7 세포주에 시험물질을 50, 100 ㎍/ml의 농도로 24시간 동안 배양한 후 상등액을 취하였다. 상등액 중 100㎕를 취하여 새로운 96 웰플레이트에 옮긴 후 100㎕ Griegrie 시약t(1% 설파닐아마이드, 0.1% 나프틸에틸렌디아민디하이드로클로라이드/2.5% H3PO4)를 넣고 10분간 실온에서 방치한 후 ELISA-reader(Bio-Rad Laboratories Inc.)를 사용하여 540 nm에서 흡광도를 측정하였다. 아질산나트륨 검량선으로부터 세포가 분비하는 NO를 계산하였다.2) Nitric oxide (NO) measurement: For NO analysis, CAYMAN (Denver, CO, USA) NO kit was used. Raw 264.7 cells were seeded in a 96-well plate at 1×10 5 cells/ml and cultured for 24 hours. took 100 μl of the supernatant was taken and transferred to a new 96-well plate, 100 μl Griegrie reagent t (1% sulfanylamide, 0.1% naphthylethylenediamine dihydrochloride/2.5% H 3 PO 4 ) was added, and left at room temperature for 10 minutes. Then, the absorbance was measured at 540 nm using an ELISA-reader (Bio-Rad Laboratories Inc.). The NO secreted by the cells was calculated from the sodium nitrite calibration curve.

3) 대식세포 활성에 따른 TNF-α 생성능 시험: 대식세포 배양물 내 TNF-α의 정량은 다중항체샌드위치(multiple antibody sandwich) 원리를 이용한 고상 ELISA 방법을 통하여 측정하였다. TNF-α 분석은 Invitrogen(Carlsbad, CA, USA)의 TNF-α 키트를 사용하였다. Raw 264.7 세포를 96 웰플레이트에 1×105 cells/ml로 분주 후에 24시간 동안 배양시킨 다음 Raw 264.7 세포주에 각 영양제를 50, 100 ㎍/ml의 농도로 24시간 동안 배양한 후 상등액을 취하였다. 상등액 중 50 ㎕를 취하여 TNF-α antibody-coated 처리된 96 웰플레이트에 옮긴 후 표준희석완충액과 biotinylated anti-TNF-α 용액을 각각 50 ㎕ 첨가한 후 90분간 실온에서 배양하였다. 배양 후, 워쉬버퍼(wash buffer)를 이용하여 4번 수세한 후 스트렙토마이신-HRP 100 ㎕를 첨가하고 30분간 실온에서 반응시켰다. 이를 4번 수세한 후 stabilized chromegen을 각 웰에 100 ㎕ 첨가한 후, 차광하여 30분간 실온에서 반응시켰다. 각 웰에 스톱용액 100 ㎕를 첨가한 후 30분 이내로 ELISA-reader(Bio-Rad Laboratories Inc.)를 이용하여 450 nm에서 측정하였다. 시료 속의 TNF-α양은 표준 TNF-α의 농도에 따라 얻어진 흡광도를 플로팅하여 얻은 표준 직선으로 산출하였다.3) TNF-α production ability test according to macrophage activity: Quantification of TNF-α in macrophage culture was measured through a solid-state ELISA method using the principle of multiple antibody sandwiches. TNF-α analysis was performed using the TNF-α kit from Invitrogen (Carlsbad, CA, USA). Raw 264.7 cells were seeded in a 96-well plate at 1×10 5 cells/ml and then cultured for 24 hours, and then each nutrient was incubated in Raw 264.7 cell lines at a concentration of 50 and 100 μg/ml for 24 hours, and then the supernatant was taken. . After taking 50 μl of the supernatant and transferring it to a 96-well plate treated with TNF-α antibody-coated, 50 μl of standard dilution buffer and biotinylated anti-TNF-α solution were added, respectively, and incubated at room temperature for 90 minutes. After incubation, after washing 4 times using a wash buffer, 100 μl of streptomycin-HRP was added and reacted at room temperature for 30 minutes. After washing with water 4 times, 100 μl of stabilized chromegen was added to each well, and then reacted at room temperature for 30 minutes after blocking light. After adding 100 μl of the stop solution to each well, measurement was performed at 450 nm using an ELISA-reader (Bio-Rad Laboratories Inc.) within 30 minutes. The amount of TNF-α in the sample was calculated with a standard straight line obtained by plotting the absorbance obtained according to the concentration of standard TNF-α.

실험결과Experiment result

1) 영양제 처리에 의한 대식세포 NO 분비 확인1) Confirmation of NO secretion by macrophages by nutrient treatment

실험결과 NO의 분비는 농도의존적으로 증가하였으며, 실시예 1 내지 7의 시험물질 처치군에서 모두 유의적인 차이를 나타내었다. 즉, NO 생산 수치는 대조군 2.69μM, 저용량군(실시예 1) 3.30μM과 고용량군(실시예 1) 3.61μM, 저용량군(실시예 2) 3.51μM과 고용량군(실시예 2) 3.75μM, 저용량군(실시예 3) 3.65μM과 고용량군(실시예 3) 3.88μM, 저용량군(실시예 4) 3.67μM과 고용량군(실시예 4) 3.86μM, 저용량군(실시예 5) 3.70μM과 고용량군(실시예 5) 3.92μM, 저용량군(실시예 6) 3.72μM과 고용량군(실시예 6) 3.90μM, 저용량군(실시예 7) 3.75μM과 고용량군(실시예 5) 3.96μM 이었으며 모든 실시예의 조성이 저용량군과 고용량군 모두 대조군에 비해 통계학적으로 유의적인 증가가 나타났다.As a result of the experiment, the secretion of NO was increased in a concentration-dependent manner, and all of the test substances treated groups of Examples 1 to 7 showed a significant difference. That is, the NO production level was 2.69 μM in the control group, 3.30 μM in the low dose group (Example 1) and 3.61 μM in the high dose group (Example 1), 3.51 μM in the low dose group (Example 2) and 3.75 μM in the high dose group (Example 2), Low dose group (Example 3) 3.65 μM and high dose group (Example 3) 3.88 μM, low dose group (Example 4) 3.67 μM, high dose group (Example 4) 3.86 μM, low dose group (Example 5) 3.70 μM The high dose group (Example 5) was 3.92 μM, the low dose group (Example 6) 3.72 μM and the high dose group (Example 6) 3.90 μM, the low dose group (Example 7) 3.75 μM and the high dose group (Example 5) were 3.96 μM. The composition of all Examples showed a statistically significant increase compared to the control group in both the low-dose group and the high-dose group.

2) 시험물질 처리에 의한 대식세포 TNF-α 분비 확인2) Confirmation of macrophage TNF-α secretion by test substance treatment

실험결과 TNF-α의 분비는 실시예 1 내지 7의 시험물질 처치군에서 고농도에서 대조군에 비해 유의적으로 증가하였다. 시험물질을 처치한 대식세포의 세포배양액에서 TNF-α 생산 분비 수치는 대조군 28.18pg/ml, 고용량군(실시예 1) 128.06pg/ml, 고용량군(실시예 2) 129.12pg/ml, 고용량군(실시예 3) 130.01pg/ml, 고용량군(실시예 4) 130.57pg/ml, 고용량군(실시예 5) 131.23pg/ml, 고용량군(실시예 6) 132.64pg/ml, 고용량군(실시예 7) 133.28pg/ml로 고용량군은 대조군에 비해 유의적인 증가를 보였다.As a result of the experiment, the secretion of TNF-α was significantly increased in the test substance treatment group of Examples 1 to 7 at high concentration compared to the control group. The level of TNF-α production secretion in the cell culture medium of macrophages treated with the test substance was 28.18pg/ml in the control group, 128.06pg/ml in the high-dose group (Example 1), 129.12pg/ml in the high-dose group (Example 2), and the high-dose group (Example 3) 130.01 pg/ml, high dose group (Example 4) 130.57 pg/ml, high dose group (Example 5) 131.23 pg/ml, high dose group (Example 6) 132.64 pg/ml, high dose group (Example 6) Example 7) At 133.28 pg/ml, the high-dose group showed a significant increase compared to the control group.

이상의 결과로부터 상기 각 실시예에 따른 조성은 독성이 없는 것으로 판단되며 면역증강의 효과를 나타내는 것으로 판단되었다.From the above results, the composition according to each of the above examples was judged to have no toxicity and was judged to exhibit the effect of enhancing immunity.

상기와 같이, 본 발명의 바람직한 실시 예를 참조하여 설명하였지만 해당 기술 분야의 숙련된 당업자라면 하기의 특허청구범위에 기재된 본 발명의 사상 및 영역으로부터 벗어나지 않는 범위 내에서 본 발명을 다양하게 수정 및 변경시킬 수 있음을 이해할 수 있을 것이다.As described above, although described with reference to preferred embodiments of the present invention, those skilled in the art can variously modify and change the present invention within the scope without departing from the spirit and scope of the present invention described in the claims below. You will understand that it can be done.

Claims (9)

6년근 고려홍삼, 글루코사민, 알로에 아보레센스, 가르시아 캄보지아 추출물(HCA), 및 가바(GABA)의 군에서 선택된 적어도 1종; 젤라틴; 및 복합비타민을 포함하며,상기 젤라틴은 전체 영양제의 중량을 기준으로 60~65 중량%, 상기 복합비타민은 1~2 중량% 첨가되며,상기 복합비타민은 복합비타민 100 중량부에 대하여 그 구성비가 비타민 A 0.2~0.3 중량부, 비타민 D3 0.05~0.06 중량부, 비타민 E 8.0~8.5 중량부, 비타민 B1 4.0~4.5 중량부, 비타민 B2 12.0~13.0 중량부, 비타민 B6 4.0~4.5 중량부, 비타민 C 8.0~8.5 중량부, 비타민 K3 1.0~1.5 중량부, 나이아신아미드 13.0~14.0 중량부, 엽산 0.2~0.3 중량부, 판토텐산칼슘 8.0~8.5 중량부, DL-메티오닌 33.0~34.0 중량부 및 카르니틴 5.0~6.0 중량부인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제.At least one selected from the group of 6-year-old Korean red ginseng, glucosamine, aloe aborescens, Garcia cambogia extract (HCA), and GABA; gelatin; and a multivitamin, wherein the gelatin is 60 to 65% by weight based on the weight of the total nutritional supplement, and 1 to 2% by weight of the multivitamin is added, and the composition ratio of the multivitamin is vitamins with respect to 100 parts by weight of the multivitamin. A 0.2 to 0.3 parts by weight, vitamin D3 0.05 to 0.06 parts by weight, vitamin E 8.0 to 8.5 parts by weight, vitamin B1 4.0 to 4.5 parts by weight, vitamin B2 12.0 to 13.0 parts by weight, vitamin B6 4.0 to 4.5 parts by weight, vitamin C 8.0 ~8.5 parts by weight, vitamin K3 1.0 to 1.5 parts by weight, niacinamide 13.0 to 14.0 parts by weight, folic acid 0.2 to 0.3 parts by weight, calcium pantothenate 8.0 to 8.5 parts by weight, DL-methionine 33.0 to 34.0 parts by weight, and carnitine 5.0 to 6.0 parts by weight A jelly-shaped snack-type oriental herbal nutritional supplement for pets characterized by its denial. 제 1항에 있어서,젤라틴, 약용성분, 및 복합비타민을 함유하는 용액과 부형제를 혼합하고, 상기 혼합물을 홍삼형상으로 성형하여 건조한 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제. According to claim 1, Jelly-shaped snack-type companion animal oriental herbal nutritional supplement, characterized in that the gelatin, medicinal ingredients, and a solution containing a multivitamin and an excipient are mixed, and the mixture is molded into a red ginseng shape and dried. 제 2항에 있어서,약용성분은 하수오, 구기자, 복분자, 황기 및 숙지황 분말인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제. According to claim 2, The medicinal ingredient is a jelly-shaped snack-type companion animal oriental herbal nutritional supplement, characterized in that the powder of sauerkraut, goji berry, bokbunja, astragalus and sukjihwang powder. 제 2항에 있어서,약용성분은 홍화씨, 가시오가피, 우슬, 독활, 두충 및 창출 분말인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제.According to claim 2, Medicinal ingredients are safflower seeds, spiny hornwort, hyssop, poison ivy, duchung, and creation powder. 제 2항에 있어서,약용성분은 산사, 후박, 백출, 맥아, 진피 및 유근피 분말인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제.According to claim 2, The medicinal ingredient is a jelly-shaped snack-type companion animal oriental nutritional supplement, characterized in that hawthorn, squash, baekchul, malt, dermis and eugeunpi powder. 제 2항에 있어서,약용성분은 어성초, 아마씨, 산수유, 백봉령, 산약, 및 흑임자 분말인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제.According to claim 2, The medicinal ingredients are jelly-shaped snack-type companion animal oriental nutritional supplement, characterized in that eoseongcho, flaxseed, cornflower oil, baekbongryeong, sanyak, and black sesame powder. 제 2항에 있어서,약용성분은 함초, 차전자, 삼백초, 길경 치커리, 및 의이인 분말인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제.According to claim 2, Medicinal ingredients are green tea, green tea, ginseng, gilgyeong chicory, and uiiin powder, a jelly-shaped snack-type companion animal oriental herbal nutritional supplement. 제 2항에 있어서,약용성분은 연잎, 맥문동, 죽여, 연자육, 석창포 및 작약 분말인 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제.According to claim 2, The medicinal ingredients are jelly-shaped snack-type companion animal oriental herbal supplements, characterized in that lotus leaf, maekmundong, porridge, yeonjayuk, seokchangpo and peony powder. 제 1항에 있어서,복합비타민의 조성은 상기 복합비타민 100 중량부에 대하여 비타민 A 0.27 중량부, 비타민 D3 0.05 중량부, 비타민 E 8.3 중량부, 비타민 B1 4.2 중량부, 비타민 B2 12.5 중량부, 비타민 B6 4.2 중량부, 비타민 C 8.3 중량부, 비타민 K3 1.1 중량부, 나이아신아미드 13.8 중량부, 엽산 0.27 중량부, 판토텐산칼슘 8.3 중량부, DL-메티오닌 33.11 중량부 및 카르니틴 5.6 중량부로 조성된 것을 특징으로 하는 젤리 형상의 간식형 반려동물 한방 영양제. According to claim 1, The composition of the multivitamin is 0.27 parts by weight of vitamin A, 0.05 parts by weight of vitamin D3, 8.3 parts by weight of vitamin E, 4.2 parts by weight of vitamin B1, 12.5 parts by weight of vitamin B2, vitamin A, based on 100 parts by weight of the multivitamin. B6 4.2 parts by weight, vitamin C 8.3 parts by weight, vitamin K3 1.1 parts by weight, niacinamide 13.8 parts by weight, folic acid 0.27 parts by weight, calcium pantothenate 8.3 parts by weight, DL-methionine 33.11 parts by weight, and carnitine 5.6 parts by weight A jelly-shaped snack-type oriental herbal supplement for pets.
KR1020210017131A 2021-02-06 2021-02-06 Light meal typed pet nutrient having a shape of red ginseng KR20220113858A (en)

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