KR20220101184A - 침전물로부터 단백질을 추출하는 방법 및 불순물을 침전시키는 방법 - Google Patents

침전물로부터 단백질을 추출하는 방법 및 불순물을 침전시키는 방법 Download PDF

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Publication number
KR20220101184A
KR20220101184A KR1020227020996A KR20227020996A KR20220101184A KR 20220101184 A KR20220101184 A KR 20220101184A KR 1020227020996 A KR1020227020996 A KR 1020227020996A KR 20227020996 A KR20227020996 A KR 20227020996A KR 20220101184 A KR20220101184 A KR 20220101184A
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KR
South Korea
Prior art keywords
protein
interest
suspension
tank
permeate
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Pending
Application number
KR1020227020996A
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English (en)
Korean (ko)
Inventor
메냐위 이브라힘 엘
노르트하임 마르쿠스 폰
Original Assignee
체에스엘 베링 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority claimed from AU2019904386A external-priority patent/AU2019904386A0/en
Application filed by 체에스엘 베링 아게 filed Critical 체에스엘 베링 아게
Publication of KR20220101184A publication Critical patent/KR20220101184A/ko
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/32—Extraction; Separation; Purification by precipitation as complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020227020996A 2019-11-20 2020-11-20 침전물로부터 단백질을 추출하는 방법 및 불순물을 침전시키는 방법 Pending KR20220101184A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2019904386 2019-11-20
AU2019904386A AU2019904386A0 (en) 2019-11-20 Novel process
PCT/EP2020/082806 WO2021099529A1 (en) 2019-11-20 2020-11-20 Method for extracting a protein from a precipitate and method for precipitating impurities

Publications (1)

Publication Number Publication Date
KR20220101184A true KR20220101184A (ko) 2022-07-19

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227020996A Pending KR20220101184A (ko) 2019-11-20 2020-11-20 침전물로부터 단백질을 추출하는 방법 및 불순물을 침전시키는 방법

Country Status (9)

Country Link
US (1) US12559520B2 (enExample)
EP (1) EP4061826A1 (enExample)
JP (1) JP2023502412A (enExample)
KR (1) KR20220101184A (enExample)
CN (1) CN114761417B (enExample)
AU (1) AU2020385637A1 (enExample)
CA (1) CA3157446A1 (enExample)
IL (1) IL293121A (enExample)
WO (1) WO2021099529A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4408572B1 (en) * 2021-09-28 2026-07-01 LPS Biosolutions A/S IMPROVED PROTEIN SORTING AND FILTRATION DEVICE
CN116120435A (zh) * 2023-02-15 2023-05-16 山西康宝生物制品股份有限公司 一种从血浆组分fiii沉淀中制备静注人免疫球蛋白的方法
US20240284944A1 (en) * 2023-02-28 2024-08-29 Xiong Wei Filtration methods and associated food products prepared using the same

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE629149A (enExample) 1962-03-03
JPH0778025B2 (ja) 1990-03-20 1995-08-23 日本赤十字社 免疫グロブリンｇの製造方法
US5886154A (en) 1997-06-20 1999-03-23 Lebing; Wytold R. Chromatographic method for high yield purification and viral inactivation of antibodies
NZ513242A (en) 1999-02-22 2003-10-31 Henry B Kopf Purification of biological substances
US6214221B1 (en) * 1999-02-22 2001-04-10 Henry B. Kopf Method and apparatus for purification of biological substances
AU784808B2 (en) 2001-04-02 2006-06-29 Kedrion Melville Inc. Prion and viral clearance process
US6875459B2 (en) * 2001-09-10 2005-04-05 Henry B. Kopf Method and apparatus for separation of milk, colostrum, and whey
RU2005129745A (ru) * 2003-02-24 2006-03-20 Джитиси Байотерапьютикс, Инк. (Us) Способы и устройство проточной фильтрации вдоль потока
AU2003238273A1 (en) * 2003-06-17 2005-02-04 Centocor, Inc. Method and apparatus for filtration of bioreactor recombinant proteins
CN101415482B (zh) * 2006-03-31 2015-04-15 金克克国际有限公司 用于化合物分离的切向流动过滤设备、系统和方法
NZ589297A (en) 2008-05-15 2011-12-22 Health L P W Process for producing milk fractions rich in secretory immunoglobulins
AU2010202125B1 (en) 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield
CN103988973A (zh) * 2009-12-30 2014-08-20 索莱有限责任公司 大豆乳清蛋白组合物及其回收方法
TWI629283B (zh) 2012-02-23 2018-07-11 巴克斯歐塔公司 來自血漿中的免疫球蛋白之ｉ-ｉｖ-１部分沉澱
WO2015133972A1 (en) * 2014-03-07 2015-09-11 Agency For Science, Technology And Research Apparatus and methods for fractionation of biological products
CN105254754A (zh) * 2015-11-28 2016-01-20 上海洲跃生物科技有限公司 一种静注人免疫球蛋白（ph4）的制备方法
IL278584B2 (en) 2018-05-17 2025-08-01 Csl Behring Ag Method and system of protein extraction
CN108939922A (zh) 2018-08-07 2018-12-07 飞潮（无锡）过滤技术有限公司 一种旋转式陶瓷膜过滤分离工艺及装置

Also Published As

Publication number Publication date
US20230002444A1 (en) 2023-01-05
JP2023502412A (ja) 2023-01-24
IL293121A (en) 2022-07-01
CN114761417A (zh) 2022-07-15
US12559520B2 (en) 2026-02-24
CA3157446A1 (en) 2021-05-27
EP4061826A1 (en) 2022-09-28
CN114761417B (zh) 2026-06-02
WO2021099529A1 (en) 2021-05-27
AU2020385637A1 (en) 2022-06-09

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