KR20220100079A - 대립유전자 검출을 위한 게놈 dna 주형의 개선된 단리 방법 - Google Patents

대립유전자 검출을 위한 게놈 dna 주형의 개선된 단리 방법 Download PDF

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KR20220100079A
KR20220100079A KR1020227022194A KR20227022194A KR20220100079A KR 20220100079 A KR20220100079 A KR 20220100079A KR 1020227022194 A KR1020227022194 A KR 1020227022194A KR 20227022194 A KR20227022194 A KR 20227022194A KR 20220100079 A KR20220100079 A KR 20220100079A
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substrate
solution
months
tip
dna
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Korean (ko)
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코니에 카오-쉐른
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아벨리노 랩 유에스에이, 인크.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020227022194A 2013-03-15 2014-03-14 대립유전자 검출을 위한 게놈 dna 주형의 개선된 단리 방법 Ceased KR20220100079A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201361852358P 2013-03-15 2013-03-15
US201361852357P 2013-03-15 2013-03-15
US61/852,357 2013-03-15
US61/852,358 2013-03-15
KR1020217009298A KR20210037750A (ko) 2013-03-15 2014-03-14 대립유전자 검출을 위한 게놈 dna 주형의 개선된 단리 방법
PCT/US2014/029466 WO2014144874A1 (en) 2013-03-15 2014-03-14 Methods for improved isolation of genomic dna templates for allele detection

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020217009298A Division KR20210037750A (ko) 2013-03-15 2014-03-14 대립유전자 검출을 위한 게놈 dna 주형의 개선된 단리 방법

Publications (1)

Publication Number Publication Date
KR20220100079A true KR20220100079A (ko) 2022-07-14

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Family Applications (3)

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KR1020227022194A Ceased KR20220100079A (ko) 2013-03-15 2014-03-14 대립유전자 검출을 위한 게놈 dna 주형의 개선된 단리 방법
KR1020217009298A Ceased KR20210037750A (ko) 2013-03-15 2014-03-14 대립유전자 검출을 위한 게놈 dna 주형의 개선된 단리 방법
KR1020157029290A Active KR102240332B1 (ko) 2013-03-15 2014-03-14 대립유전자 검출을 위한 게놈 dna 주형의 개선된 단리 방법

Family Applications After (2)

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KR1020217009298A Ceased KR20210037750A (ko) 2013-03-15 2014-03-14 대립유전자 검출을 위한 게놈 dna 주형의 개선된 단리 방법
KR1020157029290A Active KR102240332B1 (ko) 2013-03-15 2014-03-14 대립유전자 검출을 위한 게놈 dna 주형의 개선된 단리 방법

Country Status (5)

Country Link
US (1) US9856516B2 (cg-RX-API-DMAC7.html)
EP (3) EP3486328B1 (cg-RX-API-DMAC7.html)
JP (1) JP6412101B2 (cg-RX-API-DMAC7.html)
KR (3) KR20220100079A (cg-RX-API-DMAC7.html)
WO (1) WO2014144874A1 (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10889850B2 (en) * 2013-03-15 2021-01-12 Avellino Lab Usa, Inc. Methods for improved isolation of genomic DNA templates for allele detection
CN111139297B (zh) * 2020-04-02 2020-07-03 北京大学第三医院（北京大学第三临床医学院） 用于dmd的植入前胚胎遗传学诊断和产前诊断的试剂盒

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5925517A (en) 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
CA2591550C (en) 1996-06-04 2009-04-28 University Of Utah Research Foundation Monitoring hybridization during pcr
US6117635A (en) 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6018713A (en) 1997-04-09 2000-01-25 Coli; Robert D. Integrated system and method for ordering and cumulative results reporting of medical tests
JP3380744B2 (ja) 1998-05-19 2003-02-24 株式会社日立製作所 センサおよびこれを利用した測定装置
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
US6171112B1 (en) 1998-09-18 2001-01-09 Wyngate, Inc. Methods and apparatus for authenticating informed consent
AU4135600A (en) * 1999-03-29 2000-10-16 Genset Prostate cancer associated human fibronectin gene and biallelic markers
US6270970B1 (en) 1999-05-14 2001-08-07 Promega Corporation Mixed-bed solid phase and its use in the isolation of nucleic acids
ATE381626T1 (de) * 2000-04-13 2008-01-15 Univ Georgetown Genetische diagnose zur feststellung von qt- verlängerungen als unerwünschte reaktion auf arzneimittel
US8438042B2 (en) 2002-04-25 2013-05-07 National Biomedical Research Foundation Instruments and methods for obtaining informed consent to genetic tests
US20030176650A1 (en) 2001-08-09 2003-09-18 Grosse William M. Nucleic acids, polypeptides, single nucleotide polymorphisms and methods of use thereof
WO2003046526A1 (de) 2001-11-28 2003-06-05 Graffinity Pharmaceuticals Ag Spr-sensorflächenträger
US6943417B2 (en) 2003-05-01 2005-09-13 Clemson University DNA-based memory device and method of reading and writing same
US20050019757A1 (en) * 2003-06-12 2005-01-27 Stolarchuk Danylo J. Contaminant detection apparatus
WO2005015198A1 (ja) 2003-08-06 2005-02-17 Nippon Telegraph And Telephone Corporation 多孔質材料を用いた分子の検出方法ならびに該多孔質材料及び該多孔質材料の製造方法
CA2544129A1 (en) 2003-10-22 2005-05-06 The Regents Of The University Of California Methods for preparing and functionalizing nanoparticles
WO2005047534A2 (en) 2003-10-28 2005-05-26 Bayer Healthcare Ag Methods and compositions for the response prediction of malig-nant neoplasia to treatment
EP1541528A1 (en) 2003-12-08 2005-06-15 Institut Jozef Stefan Quasi-one-dimensional polymers based on the metal-chalcogen-halogen system
US20060057604A1 (en) 2004-03-15 2006-03-16 Thinkfar Nanotechnology Corporation Method for electrically detecting oligo-nucleotides with nano-particles
MXPA06013440A (es) 2004-05-19 2007-06-12 Vp Holding Llc Sensor optico con estructura estratificada de plasmon para deteccion mejorada de grupos quimicos por dispersion raman intensificada por superficie.
US7713849B2 (en) 2004-08-20 2010-05-11 Illuminex Corporation Metallic nanowire arrays and methods for making and using same
US7332329B2 (en) 2004-09-24 2008-02-19 Wisconsin Alumni Research Foundation Versatile substrate for SPR detection
WO2006096011A1 (en) 2005-03-08 2006-09-14 Medigenes Co., Ltd. PHARMACEUTICAL COMPOSITION FOR TREATING AVELLINO CORNEA DYSTROPHY COMPRISING AN ANTIBODY AGAINST TGF-β
JP2006250668A (ja) 2005-03-10 2006-09-21 Tatsuro Endo 非標識バイオチップ
EP1715326A1 (en) 2005-04-22 2006-10-25 Universität Heidelberg Sensor chip with connected non-metallic particles comprising a metallic coating
WO2007002567A2 (en) * 2005-06-23 2007-01-04 Nanosphere, Inc. Selective isolation and concentration of nucleic acids from complex samples
KR20070076532A (ko) 2006-01-18 2007-07-24 메디제네스(주) 각막이영양증 진단용 ｄｎａ 칩
CN101374850A (zh) 2006-01-18 2009-02-25 株式会社美迪基尼斯 用于角膜营养不良诊断的dna芯片
WO2007109702A2 (en) 2006-03-21 2007-09-27 Washington State University Research Foundation Genetic polymorphisms in the corticotropin-releasing hormone(crh) gene as markers for improving beef marbling score and/or subcutaneous fat depth
EP1932922A1 (de) * 2006-12-13 2008-06-18 Desitin Arzneimittel GmbH Schnelltest zum Nachweis von DNA-Sequenzen
EP2115123A4 (en) 2007-01-16 2010-07-07 Applied Biosystems Llc SELECTIVE LYSE OF SPERM CELLS
US7898658B2 (en) 2007-01-23 2011-03-01 The Regents Of The University Of California Platform for chemical and biological sensing by surface-enhanced Raman spectroscopy
KR100891096B1 (ko) 2007-02-13 2009-03-31 삼성전자주식회사 올리고머 프로브 어레이 및 이의 제조 방법
JP5222599B2 (ja) 2007-07-20 2013-06-26 株式会社日立ハイテクノロジーズ 核酸分析デバイス及びそれを用いた核酸分析装置
CN101144812B (zh) 2007-10-17 2012-02-22 中国科学院光电技术研究所 一种局域表面等离子体生化传感器的制作方法
US20120231537A1 (en) * 2008-04-30 2012-09-13 Gradalis, Inc. Highly Pure Plasmid DNA Preparations
KR101251538B1 (ko) 2009-04-17 2013-04-08 (주)아벨리노 아벨리노 각막이상증 진단용 프라이머
US8865402B2 (en) 2009-08-26 2014-10-21 Clemson University Research Foundation Nanostructured substrates for surface enhanced raman spectroscopy (SERS) and detection of biological and chemical analytes by electrical double layer (EDL) capacitance
KR101125212B1 (ko) * 2010-10-01 2012-03-21 (주)아벨리노 아벨리노 각막이상증 진단용 시스템
EP3872192A1 (en) * 2013-11-15 2021-09-01 Avellino Lab USA, Inc. Methods for multiplex detection of alleles associated with ophthalmic conditions

Also Published As

Publication number Publication date
US9856516B2 (en) 2018-01-02
US20150299773A1 (en) 2015-10-22
EP3486328A1 (en) 2019-05-22
JP2016512694A (ja) 2016-05-09
EP3825413B1 (en) 2024-03-06
EP2925895B1 (en) 2018-11-28
KR20150131271A (ko) 2015-11-24
EP3825413A1 (en) 2021-05-26
EP3486328B1 (en) 2020-11-11
HK1216034A1 (en) 2016-10-07
EP2925895A4 (en) 2016-08-17
WO2014144874A1 (en) 2014-09-18
EP2925895A1 (en) 2015-10-07
KR20210037750A (ko) 2021-04-06
KR102240332B1 (ko) 2021-04-14
JP6412101B2 (ja) 2018-10-24

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