KR20220098147A - 감지 및/또는 인증을 위한 발광 이미징 - Google Patents

감지 및/또는 인증을 위한 발광 이미징 Download PDF

Info

Publication number
KR20220098147A
KR20220098147A KR1020227016531A KR20227016531A KR20220098147A KR 20220098147 A KR20220098147 A KR 20220098147A KR 1020227016531 A KR1020227016531 A KR 1020227016531A KR 20227016531 A KR20227016531 A KR 20227016531A KR 20220098147 A KR20220098147 A KR 20220098147A
Authority
KR
South Korea
Prior art keywords
emission
species
image
article
emitting species
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020227016531A
Other languages
English (en)
Korean (ko)
Inventor
티모시 매닝 스와거
로버트 딘스
제이슨 알. 콕스
Original Assignee
씨2센스, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 씨2센스, 인크. filed Critical 씨2센스, 인크.
Publication of KR20220098147A publication Critical patent/KR20220098147A/ko
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6408Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/2823Imaging spectrometer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/443Emission spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J5/00Radiation pyrometry, e.g. infrared or optical thermometry
    • G01J5/02Constructional details
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/21Polarisation-affecting properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6489Photoluminescence of semiconductors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07DHANDLING OF COINS OR VALUABLE PAPERS, e.g. TESTING, SORTING BY DENOMINATIONS, COUNTING, DISPENSING, CHANGING OR DEPOSITING
    • G07D7/00Testing specially adapted to determine the identity or genuineness of valuable papers or for segregating those which are unacceptable, e.g. banknotes that are alien to a currency
    • G07D7/06Testing specially adapted to determine the identity or genuineness of valuable papers or for segregating those which are unacceptable, e.g. banknotes that are alien to a currency using wave or particle radiation
    • G07D7/12Visible light, infrared or ultraviolet radiation
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07DHANDLING OF COINS OR VALUABLE PAPERS, e.g. TESTING, SORTING BY DENOMINATIONS, COUNTING, DISPENSING, CHANGING OR DEPOSITING
    • G07D7/00Testing specially adapted to determine the identity or genuineness of valuable papers or for segregating those which are unacceptable, e.g. banknotes that are alien to a currency
    • G07D7/06Testing specially adapted to determine the identity or genuineness of valuable papers or for segregating those which are unacceptable, e.g. banknotes that are alien to a currency using wave or particle radiation
    • G07D7/12Visible light, infrared or ultraviolet radiation
    • G07D7/1205Testing spectral properties
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04NPICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N5/00Details of television systems
    • H04N5/30Transforming light or analogous information into electric information
    • H04N5/33Transforming infrared radiation
    • HELECTRICITY
    • H10SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10KORGANIC ELECTRIC SOLID-STATE DEVICES
    • H10K50/00Organic light-emitting devices
    • H10K50/10OLEDs or polymer light-emitting diodes [PLED]
    • H10K50/11OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers
    • H10K50/125OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers specially adapted for multicolour light emission, e.g. for emitting white light
    • H10K50/13OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers specially adapted for multicolour light emission, e.g. for emitting white light comprising stacked EL layers within one EL unit
    • H10K50/131OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers specially adapted for multicolour light emission, e.g. for emitting white light comprising stacked EL layers within one EL unit with spacer layers between the electroluminescent layers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J5/00Radiation pyrometry, e.g. infrared or optical thermometry
    • G01J2005/0077Imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6432Quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • G01N2021/6471Special filters, filter wheel
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N2021/757Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated using immobilised reagents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/062LED's
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/165Coronaviridae, e.g. avian infectious bronchitis virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plasma & Fusion (AREA)
  • Multimedia (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
KR1020227016531A 2019-10-17 2020-10-16 감지 및/또는 인증을 위한 발광 이미징 Pending KR20220098147A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962916331P 2019-10-17 2019-10-17
US62/916,331 2019-10-17
PCT/US2020/056024 WO2021076919A1 (en) 2019-10-17 2020-10-16 Luminescence imaging for sensing and/or authentication

Publications (1)

Publication Number Publication Date
KR20220098147A true KR20220098147A (ko) 2022-07-11

Family

ID=75491071

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227016531A Pending KR20220098147A (ko) 2019-10-17 2020-10-16 감지 및/또는 인증을 위한 발광 이미징

Country Status (6)

Country Link
US (2) US11726037B2 (enExample)
EP (1) EP4045881A4 (enExample)
JP (1) JP7796010B2 (enExample)
KR (1) KR20220098147A (enExample)
CN (1) CN114729890A (enExample)
WO (1) WO2021076919A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2576218B (en) * 2018-08-10 2021-09-15 De La Rue Int Ltd Security devices and methods of authentication thereof
EP4045898A4 (en) * 2019-10-17 2024-01-10 C2Sense, Inc. LUMINESCENCE IMAGING FOR CAPTURE
CN114729890A (zh) 2019-10-17 2022-07-08 C2感官有限公司 用于感测和/或认证的发光成像
US11786756B2 (en) 2020-12-30 2023-10-17 Varian Medical Systems, Inc. Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
US11759656B2 (en) 2020-12-30 2023-09-19 Varian Medical Systems, Inc. Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
US11607563B2 (en) 2020-12-30 2023-03-21 Varian Medical Systems, Inc. Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
US11712587B2 (en) 2020-12-30 2023-08-01 Varian Medical Systems, Inc. Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
US11577095B2 (en) 2020-12-30 2023-02-14 Varian Medical Systems, Inc. Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
US11638840B2 (en) * 2020-12-30 2023-05-02 Varian Medical Systems, Inc. Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
US11660473B2 (en) 2020-12-30 2023-05-30 Varian Medical Systems, Inc. Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
US11844962B2 (en) 2020-12-30 2023-12-19 Varian Medical Systems, Inc. Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
US11604564B2 (en) 2020-12-30 2023-03-14 Varian Medical Systems, Inc. Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
US11654303B2 (en) 2020-12-30 2023-05-23 Varian Medical Systems, Inc. Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
US20230280207A1 (en) * 2022-03-04 2023-09-07 Central Garden & Pet Company Photochromic pigment detection to determine uv output intensity of a uv illuminating source within a reptile cage

Family Cites Families (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822733A (en) * 1985-05-28 1989-04-18 Amoco Corporation Lifetime-resolved assay procedures
SE458968B (sv) 1987-06-16 1989-05-22 Wallac Oy Biospecifikt analysfoerfarande foer flera analyter i vilket ingaar partikelraekning och maerkning med fluorescerande maerksubstanser
JPH0694605A (ja) 1992-07-06 1994-04-08 General Electric Co <Ge> パルス電磁波源および干渉計を用いた分光撮影装置
JP3640461B2 (ja) 1996-04-03 2005-04-20 シスメックス株式会社 粒子分析装置
US5874046A (en) * 1996-10-30 1999-02-23 Raytheon Company Biological warfare agent sensor system employing ruthenium-terminated oligonucleotides complementary to target live agent DNA sequences
US6287765B1 (en) * 1998-05-20 2001-09-11 Molecular Machines, Inc. Methods for detecting and identifying single molecules
US6406914B1 (en) * 1999-03-31 2002-06-18 Nichiyu Giken Kogyo Co., Ltd. Radiation exposure dose-history indicator
JP4074136B2 (ja) * 2002-05-29 2008-04-09 浜松ホトニクス株式会社 蛍光寿命分布画像測定装置およびその測定方法
JP2005530517A (ja) * 2002-06-27 2005-10-13 ジョージア テック リサーチ コーポレイション ナノサイズ光学蛍光ラベルおよびその使用
US6756591B1 (en) * 2003-03-14 2004-06-29 Centre National De La Recherche Method and device for photothermal imaging tiny particles immersed in a given medium
US7821675B2 (en) 2003-04-04 2010-10-26 Angstrom Technologies, Inc. Methods and ink compositions for invisibly printed security images having multiple authentication features
WO2004090517A1 (ja) * 2003-04-04 2004-10-21 National Institute Of Advanced Industrial Science And Technology 蛍光寿命を利用した物質の定量用試薬、方法及び装置
US20050106876A1 (en) * 2003-10-09 2005-05-19 Taylor Charles A.Ii Apparatus and method for real time measurement of substrate temperatures for use in semiconductor growth and wafer processing
US20070117208A1 (en) * 2003-11-06 2007-05-24 Nichiyu Giken Kogyo Co., Ltd. Radiation exposure history indicator
US7173702B2 (en) * 2004-07-15 2007-02-06 Lockheed Martin Corporation Sensor comprising multi-wavelength LEDs
US7336357B2 (en) * 2004-08-13 2008-02-26 University Of Pittsburgh Multi-channel dual phase lock-in optical spectrometer
EP1817573A4 (en) * 2004-10-18 2010-02-10 Univ Macquarie FLUORESCENCE DETECTION
US7591583B2 (en) * 2005-05-18 2009-09-22 Federal-Mogul World Wide, Inc. Transient defect detection algorithm
US7419298B2 (en) * 2005-05-24 2008-09-02 United Technologies Corporation Thermal imaging method and apparatus
US8007999B2 (en) * 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
RU2354958C2 (ru) 2006-09-13 2009-05-10 ООО "Генная и клеточная терапия" Способ флуорометрического определения параметров фотосинтеза фотоавтотрофных организмов, устройство для его осуществления и измерительная камера
US7365330B1 (en) * 2006-09-18 2008-04-29 Uchicago Argonne, Llc Method for thermal tomography of thermal effusivity from pulsed thermal imaging
US8802447B2 (en) * 2006-10-05 2014-08-12 Massachusetts Institute Of Technology Emissive compositions with internal standard and related techniques
US7741045B2 (en) * 2006-11-16 2010-06-22 General Electric Company Sequential analysis of biological samples
US8305579B2 (en) * 2006-11-16 2012-11-06 Thomas Pirrie Treynor Sequential analysis of biological samples
US20080178653A1 (en) 2007-01-29 2008-07-31 Applera Corporation System and Method for Interpolative Calibration
EP2108129A4 (en) * 2007-01-30 2013-06-12 Ge Healthcare Bio Sciences TIME-CONTROLLED FLUORESCENCE PICTURE SYSTEM
FI20070171A0 (fi) 2007-02-28 2007-02-28 Hidex Oy Biotesti ja biotestivälineet
US10596387B2 (en) * 2007-04-08 2020-03-24 Immunolight, Llc. Tumor imaging with X-rays and other high energy sources using as contrast agents photon-emitting phosphors having therapeutic properties
US7777233B2 (en) * 2007-10-30 2010-08-17 Eastman Kodak Company Device containing non-blinking quantum dots
US8323221B2 (en) * 2007-11-12 2012-12-04 Koninklijke Philips Electronics N.V. Tissue temperature indicating element for ultrasound therapy
US8951473B2 (en) 2008-03-04 2015-02-10 Massachusetts Institute Of Technology Devices and methods for determination of species including chemical warfare agents
US8506159B2 (en) * 2008-09-17 2013-08-13 Nippon Steel & Sumitomo Metal Corporation Method for detecting defect in material and system for the method
GB0818151D0 (en) * 2008-10-03 2008-11-12 Central Lab Innovation And Knowledge Transf Ltd Imaging techniques
WO2010123482A2 (en) 2008-12-12 2010-10-28 Massachusetts Institute Of Technology High charge density structures, including carbon-based nanostructures and applications thereof
EP2398908B1 (en) * 2009-02-19 2013-08-21 Dako Denmark A/S Methods and compounds for detection of molecular targets
MX2011009387A (es) 2009-03-20 2011-09-28 Hoffmann La Roche Elemento de prueba para analizar un fluido corporal y metodo para su medicion.
US8456073B2 (en) 2009-05-29 2013-06-04 Massachusetts Institute Of Technology Field emission devices including nanotubes or other nanoscale articles
US20110097723A1 (en) * 2009-09-19 2011-04-28 Qun Liu Methods and reagents for analyte detection
US8187887B2 (en) 2009-10-06 2012-05-29 Massachusetts Institute Of Technology Method and apparatus for determining radiation
US9075225B2 (en) * 2009-10-28 2015-07-07 Alentic Microscience Inc. Microscopy imaging
US20110171629A1 (en) 2009-11-04 2011-07-14 Massachusetts Institute Of Technology Nanostructured devices including analyte detectors, and related methods
WO2011084641A2 (en) * 2009-12-16 2011-07-14 The Regents Of The University Of California Gold coating of rare earth nano-phosphors and uses thereof
SG10201601903YA (en) * 2010-06-08 2016-04-28 Dcg Systems Inc Three-dimensional hot spot localization
US20130087719A1 (en) * 2010-08-13 2013-04-11 Lumos Technology Co., Ltd. Light source device for time-delayed detection of fluorescence, and image pick-up system and method
WO2012044778A1 (en) 2010-09-29 2012-04-05 Massachusetts Institute Of Technology Compositions, methods, and systems comprising poly(thiophenes)
SG189894A1 (en) 2010-10-15 2013-06-28 Siemens Industry Inc Process for making a monomer solution for making cation exchange membranes
TWI460422B (zh) * 2010-10-22 2014-11-11 Dcg Systems Inc 從裝置一側作鎖相熱雷射激發並從另一側取得鎖相熱發散影像
WO2012067665A1 (en) 2010-11-18 2012-05-24 Massachusetts Institute Of Technology Charged polymers and their uses in electronic devices
US9968258B2 (en) * 2011-09-12 2018-05-15 Tufts University Imaging fluorescence or luminescence lifetime
US20140308661A1 (en) 2011-09-25 2014-10-16 Theranos, Inc. Systems and methods for multi-analysis
PL2812675T3 (pl) * 2012-02-06 2021-12-13 The Regents Of The University Of California Przenośny czytnik szybkich testów diagnostycznych
CA2865948A1 (en) * 2012-03-02 2013-09-06 Warren S. Grundfest System and method for time-resolved fluorescence imaging and pulse shaping
ES2957540T3 (es) * 2012-07-10 2024-01-22 Massachusetts Gen Hospital Sistema y método para monitorizar y tratar una superficie de un sujeto
US20140024024A1 (en) * 2012-07-17 2014-01-23 General Electric Company Methods of detecting dna, rna and protein in biological samples
US9310300B2 (en) 2012-08-03 2016-04-12 Ingeneron Incorporated Compact portable apparatus for optical assay
WO2014028861A1 (en) * 2012-08-17 2014-02-20 Apellis Pharmaceuticals, Inc. Detection of high risk drusen
WO2014065889A2 (en) * 2012-10-28 2014-05-01 Clarient Diagnostic Services, Inc. Multiplexed method for diagnosing classical hodgkin lymphoma
US8947656B2 (en) 2013-01-04 2015-02-03 The Board Of Trustees Of The University Of Illinois Smartphone biosensor
EP2954310B1 (en) * 2013-02-06 2024-01-03 Alentic Microscience Inc. Detecting and using light representative of a sample
WO2014168734A1 (en) * 2013-03-15 2014-10-16 Cedars-Sinai Medical Center Time-resolved laser-induced fluorescence spectroscopy systems and uses thereof
WO2014172269A2 (en) 2013-04-18 2014-10-23 Bio-Rad Laboratories, Inc. Fluorescence imager on a mobile device
CN105705938B (zh) * 2013-08-19 2020-11-06 休斯敦大学系统 磷光报告物
US9322051B2 (en) * 2013-10-07 2016-04-26 General Electric Company Probing of biological samples
EP2952884B1 (en) * 2014-06-04 2019-07-03 DCG Systems GmbH Method for examination of a sample by means of the lock-in thermography
JP2017525258A (ja) 2014-07-03 2017-08-31 フィリップス ライティング ホールディング ビー ヴィ 符号化光シンボルの符号化
CA2955168A1 (en) 2014-07-15 2016-01-21 C2Sense Llc Formulations for enhanced chemiresistive sensing
US20160078706A1 (en) 2014-09-17 2016-03-17 Thomas D. Pawlik Method of authenticating an object
EP3076332B1 (en) 2015-03-30 2020-06-24 Cabro S.p.A. Method to check the authenticity of articles, each provided with at least one optical reading marking
US9867250B1 (en) * 2015-04-20 2018-01-09 The Arizona Board Of Regents On Behalf Of The University Of Arizona System having a configurable pico-second pulsed LED driver circuit and photomultiplier tube biasing and gating circuits for real-time, time-resolved transient recording of fluorescence
US11466316B2 (en) * 2015-05-20 2022-10-11 Quantum-Si Incorporated Pulsed laser and bioanalytic system
WO2016187580A1 (en) * 2015-05-20 2016-11-24 Quantum-Si Incorporated Method of determining the sequence of a nuclear acid using time resolved luminescence
NO348517B1 (en) * 2015-06-11 2025-02-24 Neo Monitors As Gas monitor
JP6542044B2 (ja) * 2015-06-30 2019-07-10 オリンパス株式会社 顕微鏡システム
CN109313832B (zh) 2016-06-30 2021-02-09 锡克拜控股有限公司 成像系统和成像方法
US9563798B1 (en) 2016-08-23 2017-02-07 V.L. Engineering, Inc. Reading invisible barcodes and other invisible insignia using physically unmodified smartphone
US10948411B2 (en) * 2016-09-21 2021-03-16 University Of Houston System Blue emitting persistent phosphor compositions as diagnostic reporters
EP3301655B1 (de) 2016-09-30 2023-11-15 CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement Lumineszierendes sicherheitsmerkmal
US10809176B2 (en) 2016-10-24 2020-10-20 The Trustees Of The University Of Pennsylvania Ultra-high throughput detection of fluorescent droplets using time domain encoded optofluidics
CA3047826A1 (en) * 2016-12-22 2018-06-28 Quantum-Si Incorporated Integrated photodetector with direct binning pixel
US10972641B2 (en) 2017-02-08 2021-04-06 Essenlix Corporation Optics, device, and system for assaying
US20190008973A1 (en) * 2017-07-06 2019-01-10 Joseph Eldor Intralipid-iodine for imaging
US10670526B2 (en) * 2018-03-05 2020-06-02 Smartsens Technology (Cayman) Co., Limited DNA sequencing system with stacked BSI global shutter image sensor
US11885952B2 (en) 2018-07-30 2024-01-30 Essenlix Corporation Optics, device, and system for assaying and imaging
JP2020071152A (ja) * 2018-10-31 2020-05-07 ソニー株式会社 免疫染色方法、免疫染色システム、および免疫染色キット
US11592393B2 (en) * 2018-11-21 2023-02-28 The Board Of Trustees Of The Leland Stanford Junior University Wide-field nanosecond imaging methods using wide-field optical modulators
AU2020214839A1 (en) * 2019-01-31 2021-09-09 C2Sense, Inc. Gas sensing identification
JP2022526128A (ja) 2019-03-21 2022-05-23 シー2センス, インコーポレイテッド 揮発性イオンの検出のためのシステムおよび関連する方法
EP4045898A4 (en) 2019-10-17 2024-01-10 C2Sense, Inc. LUMINESCENCE IMAGING FOR CAPTURE
CN114729890A (zh) 2019-10-17 2022-07-08 C2感官有限公司 用于感测和/或认证的发光成像
US11873433B2 (en) * 2020-02-28 2024-01-16 Texas Christian University Near-infrared emissive graphene quantum dots method of manufacture and uses thereof

Also Published As

Publication number Publication date
WO2021076919A1 (en) 2021-04-22
US20250067670A9 (en) 2025-02-27
EP4045881A1 (en) 2022-08-24
JP2022552414A (ja) 2022-12-15
US11726037B2 (en) 2023-08-15
US20240077420A1 (en) 2024-03-07
CN114729890A (zh) 2022-07-08
US12385835B2 (en) 2025-08-12
EP4045881A4 (en) 2023-12-20
US20210116371A1 (en) 2021-04-22
JP7796010B2 (ja) 2026-01-08

Similar Documents

Publication Publication Date Title
JP7796010B2 (ja) 感知および/または認証のための発光イメージング
US11656226B2 (en) Image generation for detection and related methods
US7912653B1 (en) Nanocrystal taggants
JP2022552415A5 (enExample)
CN103534577B (zh) 基于纳米结构检测装置的检测网络
US7049148B2 (en) Method for measuring 3-dimensional orientation of a photoactive moiety
US9759660B2 (en) Sensor assembly, method, and measuring system for capturing the distribution of at least one variable of an object
WO2015052590A2 (en) System and method for detecting crude oil or gas underground using light scattering spectral analyses
Paolesse et al. Fluorescence based sensor arrays
Wei et al. The intersection of CMOS microsystems and upconversion nanoparticles for luminescence bioimaging and bioassays
Fratto et al. Leveraging a smartphone to perform time-gated luminescence measurements
Nafie Recent advances in linear and nonlinear Raman spectroscopy. Part XII
Powe et al. Molecular fluorescence, phosphorescence, and chemiluminescence spectrometry
Zhao et al. Interfacial separation-enabled all-dry approach for simultaneous visualization, transfer, and enhanced Raman analysis of latent fingerprints
Sikdar et al. Luminescent Materials for Optical Thermometry, pH Sensing, and Forensic Applications
JP2005214940A (ja) ビーズ位置情報識別方法
Boichenko et al. Luminescent filaments based on polymer modified with Eu (III) complexes for three‐dimensional printing of simple spectrophotometric devices for chemical analysis
Dini Chemical sensors based on image detectors

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

P22-X000 Classification modified

St.27 status event code: A-2-2-P10-P22-nap-X000

P22-X000 Classification modified

St.27 status event code: A-2-2-P10-P22-nap-X000

P22-X000 Classification modified

St.27 status event code: A-2-2-P10-P22-nap-X000

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

P22-X000 Classification modified

St.27 status event code: A-2-2-P10-P22-nap-X000

D21 Rejection of application intended

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D21-EXM-PE0902 (AS PROVIDED BY THE NATIONAL OFFICE)

PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11 Administrative time limit extension requested

Free format text: ST27 STATUS EVENT CODE: U-3-3-T10-T11-OTH-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11 Administrative time limit extension requested

Free format text: ST27 STATUS EVENT CODE: U-3-3-T10-T11-OTH-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11 Administrative time limit extension requested

Free format text: ST27 STATUS EVENT CODE: U-3-3-T10-T11-OTH-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11 Administrative time limit extension requested

Free format text: ST27 STATUS EVENT CODE: U-3-3-T10-T11-OTH-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000