KR20220091458A - 비-고갈성 b 세포 억제제에 의한 면역원성을 감소시키기 위한 방법 및 조성물 - Google Patents

비-고갈성 b 세포 억제제에 의한 면역원성을 감소시키기 위한 방법 및 조성물 Download PDF

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KR20220091458A
KR20220091458A KR1020227006543A KR20227006543A KR20220091458A KR 20220091458 A KR20220091458 A KR 20220091458A KR 1020227006543 A KR1020227006543 A KR 1020227006543A KR 20227006543 A KR20227006543 A KR 20227006543A KR 20220091458 A KR20220091458 A KR 20220091458A
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antibody
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프란시스코 레온
폴 던포드
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프로벤션 바이오, 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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KR1020227006543A 2019-07-30 2020-07-30 비-고갈성 b 세포 억제제에 의한 면역원성을 감소시키기 위한 방법 및 조성물 Ceased KR20220091458A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962880240P 2019-07-30 2019-07-30
US62/880,240 2019-07-30
US16/943,849 US20210032333A1 (en) 2019-07-30 2020-07-30 Methods and Compositions for Reducing Immunogenicity By Non-Depletional B Cell Inhibitors
PCT/US2020/044312 WO2021022072A1 (en) 2019-07-30 2020-07-30 Methods and compositions for reducing immunogenicity by non-depletional b cell inhibitors
US16/943,849 2020-07-30

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US (1) US20210032333A1 (https=)
JP (1) JP2022544053A (https=)
KR (1) KR20220091458A (https=)
AU (1) AU2020323596A1 (https=)
BR (1) BR112022001699A2 (https=)
CA (1) CA3149209A1 (https=)
IL (1) IL290134A (https=)
MX (1) MX2022001080A (https=)
WO (1) WO2021022072A1 (https=)

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WO2020232247A1 (en) 2019-05-14 2020-11-19 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
EP4004052A4 (en) * 2019-07-30 2023-11-01 Provention Bio, Inc. METHODS AND COMPOSITIONS FOR REDUCING IMMUNOGENICITY BY NON-DEPLETED B CELL INHIBITORS
IL298999A (en) 2020-06-11 2023-02-01 Provention Bio Inc Methods and compositions for the prevention of type 1 diabetes
JP2024520444A (ja) 2021-05-24 2024-05-24 プロヴェンション・バイオ・インコーポレイテッド １型糖尿病を治療するための方法
EP4453040A4 (en) * 2021-12-23 2025-12-24 Provention Bio Inc METHODS AND COMPOSITIONS FOR THE TREATMENT OF BARTH'S SYNDROME

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NZ573646A (en) * 2006-06-12 2012-04-27 Wyeth Llc Single-chain multivalent binding proteins with effector function
UA116479C2 (uk) * 2013-08-09 2018-03-26 Макродженікс, Інк. БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ
WO2017214096A1 (en) * 2016-06-07 2017-12-14 Macrogenics, Inc. Methods for the use of cd32b x cd79b-binding molecules in the treatment of inflammatory diseases and disorders
IL269150B2 (en) * 2017-03-16 2025-04-01 Innate Pharma Cancer treatment preparations and methods

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BR112022001699A2 (pt) 2022-05-24
IL290134A (en) 2022-03-01
AU2020323596A1 (en) 2022-02-24
JP2022544053A (ja) 2022-10-17
MX2022001080A (es) 2022-04-20
WO2021022072A1 (en) 2021-02-04
CA3149209A1 (en) 2021-02-04
US20210032333A1 (en) 2021-02-04

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