KR20220078611A - 일차 인간 세포에서 동족 t 세포 및 에피토프 반응성을 스크리닝하기 위한 고처리량 방법 - Google Patents

일차 인간 세포에서 동족 t 세포 및 에피토프 반응성을 스크리닝하기 위한 고처리량 방법 Download PDF

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KR20220078611A
KR20220078611A KR1020227012313A KR20227012313A KR20220078611A KR 20220078611 A KR20220078611 A KR 20220078611A KR 1020227012313 A KR1020227012313 A KR 1020227012313A KR 20227012313 A KR20227012313 A KR 20227012313A KR 20220078611 A KR20220078611 A KR 20220078611A
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라켈 디어링
안쿠르 다닉
스테판 포페
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리제너론 파마슈티칼스 인코포레이티드
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • A61K40/00—Cellular immunotherapy
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in epitope analysis
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KR1020227012313A 2019-10-03 2020-10-02 일차 인간 세포에서 동족 t 세포 및 에피토프 반응성을 스크리닝하기 위한 고처리량 방법 Pending KR20220078611A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962910379P 2019-10-03 2019-10-03
US62/910,379 2019-10-03
PCT/US2020/054125 WO2021067851A1 (en) 2019-10-03 2020-10-02 High-throughput method to screen cognate t cell and epitope reactivities in primary human cells

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KR20220078611A true KR20220078611A (ko) 2022-06-10

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KR1020227012313A Pending KR20220078611A (ko) 2019-10-03 2020-10-02 일차 인간 세포에서 동족 t 세포 및 에피토프 반응성을 스크리닝하기 위한 고처리량 방법

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US (1) US20210102942A1 (https=)
EP (1) EP4041868A1 (https=)
JP (2) JP7711049B2 (https=)
KR (1) KR20220078611A (https=)
CN (1) CN114616467B (https=)
AU (1) AU2020358975A1 (https=)
CA (1) CA3153119A1 (https=)
IL (1) IL291859A (https=)
WO (1) WO2021067851A1 (https=)

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CN113980899A (zh) * 2021-11-29 2022-01-28 杭州艾沐蒽生物科技有限公司 一种高通量筛选抗原特异性tcr的方法
CN117286099A (zh) * 2022-06-23 2023-12-26 富禾生医股份有限公司 用于诱导抗原特异性t细胞的方法及其在癌症或病毒感染治疗中的用途
WO2024092740A1 (zh) * 2022-11-04 2024-05-10 深圳华大生命科学研究院 检测细胞间相互作用的方法及其应用
GB202302709D0 (en) * 2023-02-24 2023-04-12 Genome Res Ltd Method of identifying t cell recpetors of interest
KR20260026101A (ko) * 2023-05-23 2026-02-25 주노 쎄러퓨티크스 인코퍼레이티드 T 세포의 활성화 마커 및 t 세포 활성화를 평가하는 방법
EP4720109A1 (en) 2023-05-25 2026-04-08 Regeneron Pharmaceuticals, Inc. T cell receptors that bind presented hpv16-, mart1-, cmv-, ebv-, or influenza- peptides
WO2025064761A1 (en) 2023-09-22 2025-03-27 Regeneron Pharmaceuticals, Inc. Kras10-18 g12d off-target peptides and uses thereof
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CN117126949B (zh) * 2023-10-26 2024-05-03 北京大学第三医院（北京大学第三临床医学院） 一种鉴定羊水样本中原代细胞的细胞类型和溯源的方法
WO2026006724A1 (en) 2024-06-28 2026-01-02 Regeneron Pharmaceuticals, Inc. Prame off-target peptides and uses thereof
WO2026006734A1 (en) 2024-06-28 2026-01-02 Regeneron Pharmaceuticals, Inc. Off-target peptide-mhc complex conformation modeling systems and methods for antigen-recognition molecule development

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CN114616467B (zh) 2026-04-07
WO2021067851A1 (en) 2021-04-08
AU2020358975A1 (en) 2022-04-21
US20210102942A1 (en) 2021-04-08
JP2025105774A (ja) 2025-07-10
JP7711049B2 (ja) 2025-07-22
CA3153119A1 (en) 2021-04-08
CN114616467A (zh) 2022-06-10
JP2022552151A (ja) 2022-12-15
EP4041868A1 (en) 2022-08-17
IL291859A (en) 2022-06-01

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