KR20220040480A - 라이실 옥시다제의 디플루오로할로알릴아민 설폰 유도체 저해제, 제조 방법, 및 이의 용도 - Google Patents

라이실 옥시다제의 디플루오로할로알릴아민 설폰 유도체 저해제, 제조 방법, 및 이의 용도 Download PDF

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KR20220040480A
KR20220040480A KR1020227006461A KR20227006461A KR20220040480A KR 20220040480 A KR20220040480 A KR 20220040480A KR 1020227006461 A KR1020227006461 A KR 1020227006461A KR 20227006461 A KR20227006461 A KR 20227006461A KR 20220040480 A KR20220040480 A KR 20220040480A
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alkyl
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cycloalkyl
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halogen
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디터 볼프강 햄프레히트
앨리슨 도로시 핀들레이
크레이그 아이반 터너
만다르 데오다르
안젤리크 엘사 그레코
울프강 자롤리멕
원빈 저우
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파맥시스 엘티디
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    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
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KR1020227006461A 2019-07-25 2020-07-24 라이실 옥시다제의 디플루오로할로알릴아민 설폰 유도체 저해제, 제조 방법, 및 이의 용도 Withdrawn KR20220040480A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2019902641A AU2019902641A0 (en) 2019-07-25 Difluorohaloallylamine sulfone derivative inhibitors of lysyl oxidases, methods of preparation, and uses thereof
AU2019902641 2019-07-25
PCT/AU2020/050759 WO2021012014A1 (en) 2019-07-25 2020-07-24 Difluorohaloallylamine sulfone derivative inhibitors of lysyl oxidases, methods of preparation, and uses thereof

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KR20220040480A true KR20220040480A (ko) 2022-03-30

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KR1020227006461A Withdrawn KR20220040480A (ko) 2019-07-25 2020-07-24 라이실 옥시다제의 디플루오로할로알릴아민 설폰 유도체 저해제, 제조 방법, 및 이의 용도

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US (1) US20220251036A1 (enExample)
EP (1) EP4003952A4 (enExample)
JP (1) JP2022544031A (enExample)
KR (1) KR20220040480A (enExample)
CN (1) CN114286816B (enExample)
AU (1) AU2020317374A1 (enExample)
BR (1) BR112022000782A2 (enExample)
CA (1) CA3145738A1 (enExample)
MX (1) MX2022001031A (enExample)
TW (1) TW202114991A (enExample)
WO (1) WO2021012014A1 (enExample)
ZA (1) ZA202202376B (enExample)

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EP4173639A4 (en) 2020-06-26 2024-03-13 RaQualia Pharma Inc. METHOD FOR SELECTING A CANCER PATIENT FOR WHICH COMBINATION THERAPY OF A RETINOID AND A CANCER TREATMENT AGENT WILL BE EFFECTIVE, AND COMBINATION DRUG OF A RETINOID AND A CANCER TREATMENT AGENT
CN113440477B (zh) * 2021-08-12 2022-10-11 海南海神同洲制药有限公司 一种低粘度酮康唑乳膏及其制备方法
US12233056B2 (en) 2022-04-06 2025-02-25 Syntara Limited Lysyl oxidase inhibitors for treating myeloid malignancies
GB202209624D0 (en) 2022-06-30 2022-08-17 Institute Of Cancer Res Royal Cancer Hospital Prodrugs
GB202209622D0 (en) 2022-06-30 2022-08-17 Institute Of Cancer Res Royal Cancer Hospital Compounds

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US8426587B2 (en) * 2007-11-21 2013-04-23 Pharmaxis Ltd. Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor
CA2871793C (en) * 2012-05-02 2020-09-15 Pharmaxis Ltd. Substituted 3-haloallylamine inhibitors of ssao and uses thereof
MX376835B (es) * 2015-03-06 2025-03-07 Pharmakea Inc Inhibidores de lisil oxidasa tipo 2 fluorinados y usos de los mismos.
AU2017218889A1 (en) * 2016-02-09 2018-08-30 Pharmakea, Inc. Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof
SG11201806700RA (en) * 2016-02-12 2018-09-27 Pharmaxis Ltd Haloallylamine indole and azaindole derivative inhibitors of lysyl oxidases and uses thereof
CN110709385A (zh) * 2017-03-02 2020-01-17 法玛西斯有限公司 赖氨酰氧化酶的卤代烯丙胺吡唑衍生物抑制剂及其用途
GB201716871D0 (en) * 2017-10-13 2017-11-29 Inst Of Cancer Research: Royal Cancer Hospital Compounds
AR115906A1 (es) * 2018-08-03 2021-03-10 Pharmaxis Ltd Derivados de haloalilamina sulfona como inhibidores de lisil oxidasas

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MX2022001031A (es) 2022-02-23
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AU2020317374A1 (en) 2022-02-03
ZA202202376B (en) 2023-11-29
EP4003952A1 (en) 2022-06-01
EP4003952A4 (en) 2023-08-23
CA3145738A1 (en) 2021-01-28
WO2021012014A1 (en) 2021-01-28
JP2022544031A (ja) 2022-10-17
BR112022000782A2 (pt) 2022-03-15
CN114286816A (zh) 2022-04-05

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