KR20220004076A - 리툭시맙-내성 키메라 항원 수용체 및 이의 용도 - Google Patents

리툭시맙-내성 키메라 항원 수용체 및 이의 용도 Download PDF

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KR20220004076A
KR20220004076A KR1020217036085A KR20217036085A KR20220004076A KR 20220004076 A KR20220004076 A KR 20220004076A KR 1020217036085 A KR1020217036085 A KR 1020217036085A KR 20217036085 A KR20217036085 A KR 20217036085A KR 20220004076 A KR20220004076 A KR 20220004076A
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토마스 찰스 페르텔
바브라 존슨 사수
마크 더블유 레오날드
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알로젠 테라퓨틱스 인코포레이티드
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
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    • A61K40/4211—CD19 or B4
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • C07K2319/00—Fusion polypeptide
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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KR1020217036085A 2019-04-26 2020-04-24 리툭시맙-내성 키메라 항원 수용체 및 이의 용도 Pending KR20220004076A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962839455P 2019-04-26 2019-04-26
US62/839,455 2019-04-26
US202063005041P 2020-04-03 2020-04-03
US63/005,041 2020-04-03
PCT/US2020/029775 WO2020219848A1 (en) 2019-04-26 2020-04-24 Rituximab-resistant chimeric antigen receptors and uses thereof

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KR20220004076A true KR20220004076A (ko) 2022-01-11

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KR1020217036085A Pending KR20220004076A (ko) 2019-04-26 2020-04-24 리툭시맙-내성 키메라 항원 수용체 및 이의 용도

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US (2) US11896617B2 (https=)
EP (2) EP4295851A3 (https=)
JP (2) JP7664180B2 (https=)
KR (1) KR20220004076A (https=)
CN (1) CN113728001B (https=)
AU (2) AU2020263495B2 (https=)
BR (1) BR112021021178A2 (https=)
CA (1) CA3134308A1 (https=)
CO (1) CO2021014121A2 (https=)
DK (1) DK3959235T5 (https=)
ES (1) ES2961314T3 (https=)
FI (1) FI3959235T3 (https=)
IL (1) IL287487A (https=)
MX (1) MX2021012820A (https=)
MY (1) MY204280A (https=)
PE (1) PE20212369A1 (https=)
PH (1) PH12021552415A1 (https=)
SA (1) SA521430654B1 (https=)
SG (1) SG11202111031RA (https=)
TW (1) TWI865517B (https=)
WO (1) WO2020219848A1 (https=)

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AU2020263495B2 (en) 2025-09-25
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CA3134308A1 (en) 2020-10-29
CO2021014121A2 (es) 2021-10-29
BR112021021178A2 (pt) 2022-03-15
JP2022532996A (ja) 2022-07-21
FI3959235T3 (fi) 2023-09-27
MY204280A (en) 2024-08-21
JP2025109712A (ja) 2025-07-25
IL287487A (en) 2021-12-01
JP7664180B2 (ja) 2025-04-17
AU2025279733A1 (en) 2026-01-15
DK3959235T5 (da) 2024-08-05
US20240277763A1 (en) 2024-08-22
WO2020219848A1 (en) 2020-10-29
US12447178B2 (en) 2025-10-21
SG11202111031RA (en) 2021-11-29
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