KR20220001161A - Composition for skin protection, including extracts derived from natural products - Google Patents

Abstract

The present invention relates to a composition for skin protection comprising an extract derived from a natural product, in which the composition for skin protection does not use any artificial compounds, and thus is harmless to the human body, and also contains a composition extracted from a natural product having excellent skin protection and moisturizing effects, so as to minimize damage to keratinous tissues such as skin tissue, nails and the like. The material contained in the composition of the present invention, which is derived from a natural product, is non-toxic, does not cause side effects even when applied to the human body, and thus highly useful as a cosmetic composition, a hand sanitizer additive, or the like. Therefore, the composition is utilized as an external preparation for skin such as suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing oil, powder foundation, emulsion foundation, wax foundation, detergent, spray, and the like.

Description

A composition for skin protection comprising an extract derived from natural products {COMPOSITION FOR SKIN PROTECTION, INCLUDING EXTRACTS DERIVED FROM NATURAL PRODUCTS}

The present invention relates to a composition for skin protection comprising an extract derived from a natural product and a method for preparing the same.

As the most external organ of the body, the skin has various functions and at the same time has a great influence on appearance and image. As it covers the outer surface of the body, it can be said to be an organ that plays the role of the body's primary defense against the external environment, such as preventing the evaporation of moisture, controlling body temperature, protecting the body from external stimuli such as ultraviolet rays, and preventing the intrusion of harmful microorganisms. In addition, the skin protects the skin from physical and chemical injuries, infections of microorganisms and parasites such as bacteria and fungi, damage caused by ultraviolet rays, and drying, while also acting as a nerve receptor for various external stimuli, and recognizes external antigens. It also serves to provide immune cells.

Such skin can be easily damaged by various external factors. In these damage processes, oxides (reactive oxygen) are rapidly generated, and skin damage caused by oxides directly leads to damage to the stratum corneum. When the stratum corneum is damaged, since it has the same effect as a damaged barrier, secondary infection by microorganisms may proceed, and the damaged area gradually deteriorates and develops into a wound. In addition, the amount of percutaneous moisture loss increases through the damaged skin, resulting in skin dryness, which is accompanied by abnormal sebum secretion due to rapid sebum secretion to prevent this, which may make the skin too dry or conversely too oily. These various complex skin problems can ultimately be exacerbated by skin itching, erythema, tissue damage, and the like. Therefore, by properly treating the above series of processes step by step, skin damage can be minimized.

The skin is largely composed of three layers: the epidermis, dermis, and subcutaneous adipose tissue. The epidermis is divided from the outside to the inside into the stratum corneum, clear layer, granular layer, and basal layer. The stratum corneum, the outermost layer of the epidermis, is the most important structure of the skin barrier function and consists of non-nucleated flat corneocytes and SC intercellular lipids. The multi-lamellar lipid layer formed of intercellular lipids such as ceramide, cholesterol, and fatty acids synthesized by keratinocytes of the skin barrier maintained through the division and differentiation process of normal epidermal cells is a protective barrier to prevent moisture in the skin from evaporating. plays a role

Various types of lipids exist between the keratinocytes of the stratum corneum of the skin, and these lipids exist between the keratinocytes to prevent evaporation of skin moisture and function as a skin barrier to protect the skin from external stimuli or contamination.

In addition, in the cosmetic industry, a number of products using natural products have been developed to reduce skin irritation caused by various chemicals. Natural ingredients have fewer side effects on the skin, and as consumers' response to cosmetics using natural ingredients increases, skin for the purpose of preventing and improving skin damage, alleviating skin inflammation or moisturizing, which has recently been attracting attention in the art. Most of the protective compositions are prepared by combining various substances extracted from natural products.

Natural extracts used in skin protection compositions for the purpose of preventing and improving skin damage include animal and plant extracts that help skin moisturizing effect, natural polymers such as collagen, skin cell activators such as amino acids and vitamins, or glycerin, 1, Moisturizers such as 3-butylene glycol are widely used. For example, Korean Patent No. 424726 discloses a skin protection cosmetic composition containing vitamin C and phytosphingosine, and Korean Patent No. 364289 discloses alpha-hydroxy acid (AHA) and its skin irritation. Disclosed is a skin protection cosmetic composition containing epidermal growth factor (EGF) as a component for alleviating skin irritation.

However, the antioxidant, skin cell activator or moisturizer used in the composition for skin protection has a difficulty in using components suitable for each purpose separately, and due to the reactivity or characteristics between these components, and the instability of the formulation, these substances can be used at the same time. There has been a difficult problem to use. In addition, in the case of cosmetics, food, and pharmaceuticals, there are cases where the combination in pharmaceuticals cannot be used at all in cosmetics, because each licensed ingredient is different.

For example, antibiotics are powerful substances that can control microorganisms, but they can only be used in the pharmaceutical field, and there are cases where it cannot be used in cosmetics or food.

For this reason, there is a need for the development of a substance that can be easily used in medicine, cosmetics, food, etc. as a substance that is stable to the human body having antioxidant activity, anti-inflammatory effect, wound healing effect and moisturizing effect at the same time.

One object of the present invention is to provide a composition for skin protection comprising an extract derived from a natural product that has excellent antioxidant effect, anti-inflammatory activity, wound healing effect and moisturizing effect at the same time and has a safe effect when applied to the human body, and a method for manufacturing the same.

Another object of the present invention is to provide a composition for improving or preventing skin diseases comprising the composition for skin protection as an active ingredient.

Another object of the present invention is to provide a cosmetic comprising the composition as an active ingredient.

One aspect of the present invention for solving the above problems, a natural product-derived extract having a skin protection effect, 70 to 85% by weight of a solvent; 1 to 10% by weight of benzyl alcohol; 1 to 10% by weight of an emollient; 1 to 10% by weight of a gelling agent; And it provides a composition for skin protection comprising the remaining amount of purified water.

Specifically, the extract derived from the natural product may mean a mixed extract of a natural product having a skin protection effect, and the composition for skin protection derived from the natural product is rosemary, sea buckthorn, almond, garlic, papaya, egg yolk, lemon and horsetail. One or more extracts selected from the group consisting of; and olive oil and castor oil.

Specifically, the extract contains 8 to 10 parts by weight of rosemary, 8 to 10 parts by weight of sea buckthorn, 4 to 6 parts by weight of almonds, 2 to 3 parts by weight of garlic, 2 to 3 parts by weight of papaya, 4 to 6 parts by weight of egg yolk, lemon After mixing 8 to 10 parts by weight and 10 to 15 parts by weight of horsetail, heating at 100 ° C for 10 minutes, decoction at a temperature of 60 to 80 ° C over low heat for 2 hours or more, hot water extraction, and then 80 to 90 ° It may be prepared through a process of heating to C for 24 to 36 hours and concentrating to 6.5 to 7.5% by weight of the initial weight, but is not limited thereto and may be applied by appropriately changing it as needed.

The rosemary serves to make the skin shiny, and olive oil and castor oil (castor oil) have an effect of alleviating damage to the skin and strengthening the skin barrier. The almond and sea buckthorn have moisturizing and nourishing effects. In addition, the garlic is a natural antibacterial agent that protects the skin from mold or toxins that harm skin health. Furthermore, the papaya, egg yolk, and lemon are also natural ingredients and have the effect of strengthening the skin and alleviating damage.

In the present invention, the term “horsetail” refers to a perennial plant of the vascular plant genus Psoridae, also called a genus leopard or bambab. In folklore, the raw stem of horsetail is eaten as a vegetable, and the nutritious stem is also used as medicine. Horsetail has the property of lowering heat and excreting urine well, so it has been used as a hemostatic agent for people with a lot of body heat, nosebleeds, hematemesis, and excessive menstruation, and is also used as a diuretic to promote excretion. It is also known to be used as a cleanser for oily skin and eczema, as it is rich in silicic acid, an acne treatment ingredient. In the present invention, from the fact that horsetail has the effect of strengthening the skin and supplying nutrients to make it strong, it was used as a hand and nail nutrient in the private sector, and it was used as a raw material for the composition for skin protection derived from a natural product of the present invention.

The “extract” refers to a solvent in which the active ingredient contained in the extraction raw material is transferred by contacting the solvent and the extraction raw material under specific conditions. They can all be included regardless. For example, extracts of components soluble in solvents from natural products using water or organic solvents, specific components of natural products, for example, products obtained by extracting only specific components such as oil may be included.

It may include extracts of all formulations that can be formed using the extract itself and the extract, such as a preparation or a purified product of the extract, or a mixture thereof. Furthermore, the extract may be extracted from natural, hybrid or variegated plants, and may also be extracted from plant tissue cultures.

The method of extracting the extract of the present invention may be extracted according to a method commonly used in the art. Non-limiting examples of the extraction method include cold extraction, hot water extraction, ultrasonic extraction, filtration, reflux extraction, extrusion extraction, and the like, and these may be performed alone or in combination of two or more methods.

The type of the extraction solvent used in the present invention is not particularly limited, and any solvent known in the art may be used as needed. Non-limiting examples of the extraction solvent include water; C1-C4 lower alcohols, such as methanol, ethanol, propyl alcohol, and butyl alcohol; polyhydric alcohols such as glycerin, butylene glycol and propylene glycol; and hydrocarbon solvents such as methyl acetate, ethyl acetate, acetone, benzene, hexane, diethyl ether, and dichloromethane; Alternatively, a mixture thereof may be used, and specifically, water, lower alcohol, 1,3-butylene glycol, and ethyl acetate may be used alone or in combination of two or more. In addition, the extract extracted as described above is filtered to remove floating solid particles, for example, filtered using nylon or the like, or filtered using freeze filtration, etc. It can be used after drying.

Specifically, the solvent may be methyl acetate, ethyl acetate, or a mixture thereof, more specifically 70 to 85% by weight of methyl acetate, 70 to 85% by weight of ethyl acetate, or 70 to 85% by weight of a mixture of methyl acetate and ethyl acetate Weight% may be included, but is not limited thereto.

In the present invention, the “emollient” is a substance added to soothe or protect the skin, and includes cetyl alcohol, acetylated lanolin alcohol, caprylic acid/capric acid triglyceride, glycerin, and bis-ethoxydiglycol. It may be one or more selected from the group consisting of succinate (Bis-Ethoxydiglycol Succinate), specifically bis-ethoxydiglycol succinate, but is not limited thereto.

In the present invention, the "gelling agent" is a substance added to adjust the viscosity of the composition of the present invention, and includes alginic acid and salts thereof; Cellulose derivatives such as carboxymethylcellulose, methylcellulose (eg Methocel ^® ), hydroxypropylmethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose (eg Klucel ^® ), ethylcellulose (eg Ethocel ^® ) and microcrystalline cellulose (eg Avicel ^® ); microcrystalline dextrose; amylose; magnesium aluminum silicate; polysaccharide acids; bentonite; gelatin; polyvinylpyrrolidone/vinyl acetate copolymer; crospovidone; povidone; starch; pregelatinized starch; Tragagant, dextrin, sugars such as sucrose (eg Dipac ^® ), glucose, dextrose, molasses, mannitol, sorbitol, xylitol (eg Xylitab ^® ) and lactose; Natural or synthetic rubbers such as acacia, tragagant, ghatti gum, mucilage of isapol husks, polyvinylpyrrolidone such as Polyvidone ^® CL, coli at least one selected from the group consisting of Kollidon ^® CL, Polyplasdone ^® XL-10), larch arabogalactan, Veegum ^{®, polyethylene glycol, wax, sodium alginate} may be, and specifically may be methyl cellulose, but is not limited thereto.

In the present invention, the purified water can soften the feeling of use of the composition for skin protection of the present invention, and is added to dissolve the gelling agent, such as methyl cellulose, because it does not dissolve in the solvent. Specifically, the purified water may be prepared by mixing the remaining components except for purified water and adding as much as the amount corresponding to the remaining amount, and may be added from 0% by weight to 27% by weight, which does not contain purified water at all, It is not limited thereto, and may be appropriately changed and applied as needed.

Another aspect of the present invention provides a cosmetic composition comprising the composition for skin protection.

In the present invention, the cosmetic composition comprises a softening lotion, a nutrient lotion, a moisture cream, a nourishing cream, a massage cream, an essence, an ampoule, a gel, an eye cream, a cleansing cream, a cleansing foam, a cleansing water, a pack, a mist, a spray and a powder. It can be formulated with one or more selected from. Specifically, the cosmetic composition may be formulated in the form of a mist for skin whitening and moisturizing, but is not limited thereto.

The cosmetic composition may be formulated by a conventional method. In the formulation of external skin preparations, reference may be made to the contents disclosed in Remington's Pharmaceutical Science, Mack Publishing Company, Easton PA, and in the formulation of cosmetic compositions, International cosmetic ingredient dictionary, 6th ed (The cosmetic, Toiletry and Fragrance Association) , Inc., Washington, 1995) may be referred to.

Specifically, the cosmetic composition can be prepared in general emulsified formulations and solubilized formulations. For example, lotion, such as a softening lotion or a nourishing lotion; emulsions such as facial lotions and body lotions; creams such as nourishing creams, moisturizing creams, and eye creams; essence; makeup ointment; spray; gel; pack; sunscreen; makeup base; foundations such as liquid type, solid type or spray type; powder; makeup removers such as cleansing creams, cleansing lotions, and cleansing oils; Alternatively, it may be formulated as a cleaning agent such as a cleansing foam, soap, body wash, but is not limited thereto. In addition, the cosmetic composition may be formulated as an ointment, a patch, a gel, a cream, or a spray, but is not limited thereto.

In the cosmetic composition, in addition to the essential components in each formulation, other components may be appropriately blended within the range that does not impair the purpose according to the present invention according to the type or purpose of use, etc. of the formulation.

The cosmetic composition may include a conventionally acceptable carrier, for example, oil, water, surfactant, humectant, lower alcohol, thickener, chelating agent, colorant, preservative, fragrance, etc. may be appropriately blended, but is limited thereto no.

The acceptable carrier may vary depending on the formulation. For example, when formulated into an ointment, paste, cream or gel, animal oil, vegetable oil, wax, paraffin, starch, tracanth, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc, zinc oxide or their Mixtures can be used

When the cosmetic composition is formulated as a powder or spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, polyamide powder, or mixtures thereof may be used as a carrier component, and in the case of a spray, chlorofluorohydro It may further contain a propellant such as carbon, propane, butane or dimethyl ether.

When the cosmetic composition is formulated as a solution or emulsion, a solvent, solubilizer, or emulsifier may be used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl benzoate, propylene glycol, 1,3-Butylglycol oil may be used, and in particular, cottonseed oil, peanut oil, corn germ oil, olive oil, castor oil and sesame oil, glycerol fatty esters, fatty acid esters of polyethylene glycol or sorbitan may be used.

When the cosmetic composition is formulated as a suspension, a liquid diluent such as water, ethanol or propylene glycol as a carrier component, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester; Microcrystalline cellulose, aluminum metahydroxide, bentonite, agar or tracanth and the like can be used.

When the cosmetic composition is formulated as a soap, alkali metal salt of fatty acid, fatty acid hemiester salt, fatty acid protein hydrolyzate, isethionate, lanolin derivative, aliphatic alcohol, vegetable oil, glycerol, sugar, etc. can be used

The cosmetic composition is a fatty substance, organic solvent, solubilizer, thickening agent, gelling agent, softening agent, antioxidant, suspending agent, stabilizing agent, foaming agent, and fragrance commonly used in the industry depending on the quality or function of the final product. , surfactants, water, ionic or nonionic emulsifiers, fillers, sequestering agents, chelating agents, preservatives, blocking agents, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic active agents, commonly used in cosmetics It may additionally contain adjuvants commonly used in the field of cosmetics or dermatology, such as any other ingredients.

However, the adjuvant and its mixing ratio may be appropriately selected so as not to affect the desirable properties of the cosmetic composition according to the present invention.

The composition for skin protection comprising an extract derived from a natural product of the present invention is harmless to the human body because the composition for skin protection does not use an artificial compound, and contains a composition extracted from a natural product that has excellent skin protection and moisturizing effects, thereby providing skin tissue and keratin such as nails Tissue damage can be minimized.

In addition, the material contained in the composition of the present invention is derived from a natural product and is non-toxic, and does not cause side effects even when applied to the human body, so that it is highly useful as a cosmetic composition or a hand sanitizer additive.

Therefore, the composition is utilized as an external preparation for the skin such as suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing oil, powder foundation, emulsion foundation, wax foundation, detergent and spray useful for doing

It should be understood that the effects of the present invention are not limited to the above-described effects, and include all effects that can be inferred from the configuration of the invention described in the detailed description or claims of the present invention.

Hereinafter, the present invention will be described in detail by way of Examples. However, the following examples only illustrate the present invention, and the present invention is not limited by the following examples.

Example 1. Preparation of a composition for skin protection derived from a natural product

In order to prepare the composition for skin protection of the present invention, an extract derived from a natural product exhibiting a skin care effect was prepared.

Specifically, the natural product-derived nail protection composition comprises 8 to 10 parts by weight of rosemary, 8 to 10 parts by weight of sea buckthorn, 4 to 6 parts by weight of almonds, 2 to 3 parts by weight of garlic, 2 to 3 parts by weight of papaya, 4 to 4 egg yolks. 6 parts by weight, 8 to 10 parts by weight of lemon, and 10 to 15 parts by weight of horsetail were washed well and mixed uniformly, and the mixture was prepared to be 100 g.

After pulverizing the mixture, distilled water was added 2 to 4 times by weight, heated at 100 ° C for 10 minutes, and then heated over low heat at a temperature of 60 to 80 ° C for 2 hours or more to extract hot water.

Thereafter, the extract is heated at 80 to 90 ° C for 24 to 36 hours to concentrate to 6.5 to 7.5 wt % of the initial weight, and olive oil and castor (castor) oil are added thereto to obtain a composition for skin protection derived from natural products. prepared.

Preparation Example 1. Preparation of essence containing the extract of the present invention

As shown in Table 1 below, a cosmetic composition of an essence formulation was prepared (unit: wt%).

Raw material name content (wt%) cetearyl alcohol 2 cetearyl glucoside One silica 0.5 glycerin 10 extract of the present invention 5 Purified water To 100

Experimental Example 1. Confirmation of skin moisturizing effect

In order to find out how long the skin moisturizing composition containing the extract derived from a natural product of the present invention is applied once, the composition was given to 24 adults in their 30s and 50s who complained of dryness or who had dry skin. After application on the palms and backs of the hands, the skin moisture content was measured using a corneometer (CM820 courage Khazaka electronic GmbH, Germany) for 8 hours. Using a coniometer, the amount of moisture present in the epidermis of the skin can be measured using a sensor, and the moisture content can be measured by quantifying it and calculating the amount of moisture.

Specifically, the conia meter probe is placed on the skin area to be measured, and when the probe is pressed on the skin, the electrical conductivity of the skin is digitized and displayed on the screen through the sensor, and the measurement was performed by confirming it.

In addition, in addition to the composition of Example 1 of the present invention, commercially available hand sanitizer (Comparative Example 1) and baby lotion (Comparative Example 2) were compared together.

In the above method, the moisture content of the skin was measured using a coniometer under constant temperature and humidity conditions (24° C., humidity 40%) before the start of application in the above method and used as the basic value, and the change after 2 hours, 4 hours and 8 hours was measured. . The results are shown in Table 2 below.

sample Skin moisture content (%) before application after 2 hours after 4 hours after 8 hours Example 1 28.2 40.0 36.4 33.5 Comparative Example 1 28.1 20.1 22.5 25.1 Comparative Example 2 28.4 37.2 35.8 32.2

As shown in Table 2 above, when the extract of Example 2 of the present invention was applied, excellent moisturizing power lasted for a long time and the skin moisture content was also increased. It was confirmed that the composition of Example 1 of the present invention exhibited an excellent effect even compared to the baby lotion (Comparative Example 2), which is generally known to have an excellent moisturizing effect.

The above description of the present invention is for illustration, and those of ordinary skill in the art to which the present invention pertains can understand that it can be easily modified into other specific forms without changing the technical spirit or essential features of the present invention. will be. Therefore, it should be understood that the embodiments described above are illustrative in all respects and not restrictive. For example, each component described as a single type may be implemented in a dispersed form, and likewise components described as distributed may be implemented in a combined form.

The scope of the present invention is indicated by the following claims, and all changes or modifications derived from the meaning and scope of the claims and their equivalents should be construed as being included in the scope of the present invention.

Claims (4)

A natural product-derived extract having a skin protective effect, 70 to 85% by weight of a solvent; 1 to 10% by weight of benzyl alcohol; 1 to 10% by weight of an emollient; 1 to 10% by weight of a gelling agent; And a composition for skin protection comprising the remaining amount of purified water. According to claim 1,
The extract derived from the natural product means one or more extracts selected from the group consisting of rosemary, sea buckthorn, almond, garlic, papaya, egg yolk, lemon and horsetail, which are natural products having a skin protection effect, a composition for skin protection. 3. The method of claim 2,
The extract is water as an extraction solvent; C1-C4 lower alcohols, such as methanol, ethanol, propyl alcohol, and butyl alcohol; polyhydric alcohols such as glycerin, butylene glycol and propylene glycol; and hydrocarbon solvents such as methyl acetate, ethyl acetate, acetone, benzene, hexane, diethyl ether, and dichloromethane; Or a composition for skin protection that is extracted using any one or more of a mixture thereof. According to claim 1,
The gelling agent, alginic acid and salts thereof; Cellulose derivatives such as carboxymethylcellulose, methylcellulose (eg Methocel ^® ), hydroxypropylmethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose (eg Klucel ^® ), ethylcellulose (eg Ethocel ^® ) and microcrystalline cellulose (eg Avicel ^® ); microcrystalline dextrose; amylose; magnesium aluminum silicate; polysaccharide acids; bentonite; gelatin; polyvinylpyrrolidone/vinyl acetate copolymer; crospovidone; povidone; starch; pregelatinized starch; Tragagant, dextrin, sugars such as sucrose (eg Dipac ^® ), glucose, dextrose, molasses, mannitol, sorbitol, xylitol (eg Xylitab ^® ) and lactose; Natural or synthetic rubbers such as acacia, tragagant, ghatti gum, mucilage of isapol husks, polyvinylpyrrolidone such as Polyvidone ^® CL, coli at least one selected from the group consisting of Kollidon ^® CL, Polyplasdone ^® XL-10), larch arabogalactan, Veegum ^{®, polyethylene glycol, wax, sodium alginate} The composition for skin protection.