KR20210135261A - 인플루엔자 ha 스플릿 백신의 제조 방법 - Google Patents

인플루엔자 ha 스플릿 백신의 제조 방법 Download PDF

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Publication number
KR20210135261A
KR20210135261A KR1020217030986A KR20217030986A KR20210135261A KR 20210135261 A KR20210135261 A KR 20210135261A KR 1020217030986 A KR1020217030986 A KR 1020217030986A KR 20217030986 A KR20217030986 A KR 20217030986A KR 20210135261 A KR20210135261 A KR 20210135261A
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South Korea
Prior art keywords
influenza
split vaccine
vaccine
split
antibody
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Pending
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KR1020217030986A
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English (en)
Korean (ko)
Inventor
요시마사 다카하시
유 아다치
마나부 아토
Original Assignee
국립감염증연구소장이 대표하는 일본국
다이닛본 스미토모 세이야꾸 가부시끼가이샤
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Application filed by 국립감염증연구소장이 대표하는 일본국, 다이닛본 스미토모 세이야꾸 가부시끼가이샤 filed Critical 국립감염증연구소장이 대표하는 일본국
Publication of KR20210135261A publication Critical patent/KR20210135261A/ko
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020217030986A 2019-03-04 2020-03-03 인플루엔자 ha 스플릿 백신의 제조 방법 Pending KR20210135261A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2019-038662 2019-03-04
JP2019038662 2019-03-04
PCT/JP2020/008974 WO2020179797A1 (ja) 2019-03-04 2020-03-03 インフルエンザｈａスプリットワクチンの製造方法

Publications (1)

Publication Number Publication Date
KR20210135261A true KR20210135261A (ko) 2021-11-12

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KR1020217030986A Pending KR20210135261A (ko) 2019-03-04 2020-03-03 인플루엔자 ha 스플릿 백신의 제조 방법

Country Status (15)

Country Link
US (1) US12491240B2 (enExample)
EP (1) EP3936147A4 (enExample)
JP (1) JP7545955B2 (enExample)
KR (1) KR20210135261A (enExample)
CN (1) CN114096273A (enExample)
AU (1) AU2020233456A1 (enExample)
BR (1) BR112021017310A8 (enExample)
CA (1) CA3132578A1 (enExample)
EA (1) EA202192398A1 (enExample)
IL (1) IL285984A (enExample)
MX (1) MX2021010685A (enExample)
MY (1) MY208974A (enExample)
PH (1) PH12021552094A1 (enExample)
SG (1) SG11202109566XA (enExample)
WO (1) WO2020179797A1 (enExample)

Families Citing this family (3)

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Publication number Priority date Publication date Assignee Title
US12059462B2 (en) 2018-07-23 2024-08-13 Japan As Represented By Director General Of National Institute Of Infectious Diseases Composition containing influenza vaccine
EP4054630A2 (en) * 2019-11-07 2022-09-14 Seqirus UK Limited Compositions and methods for producing a viral vaccine with reduced particle size
AU2024264265A1 (en) * 2023-04-26 2025-11-13 Japan Institute For Health Security Anti-influenza antibody

Citations (1)

* Cited by examiner, † Cited by third party
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JP2016516090A (ja) 2013-03-29 2016-06-02 セルトリオン・インコーポレイテッド ２以上のインフルエンザａウイルス中和結合分子を含む組成物

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US8278083B2 (en) 2004-03-22 2012-10-02 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Inactivated influenza virus compositions
US20230201329A1 (en) * 2006-07-17 2023-06-29 Glaxosmithkline Biologicals Sa Influenza vaccine
US20090181078A1 (en) * 2006-09-26 2009-07-16 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
US8044056B2 (en) 2007-03-20 2011-10-25 Dainippon Sumitomo Pharma Co., Ltd. Adenine compound
US9452209B2 (en) * 2007-04-20 2016-09-27 Glaxosmithkline Biologicals Sa Influenza vaccine
BRPI0911699B8 (pt) 2008-07-25 2023-02-28 Inst Res Biomedicine vetor, célula, composição farmacêutica, uso de um anticorpo, ou fragmento de ligação a antígeno deste
WO2010047509A2 (ko) 2008-10-24 2010-04-29 아주대학교 산학협력단 친화도와 안정성이 향상된 항 ｄｒ5 항체, 및 이를 포함하는 암 예방 또는 치료용 조성물
US8883479B2 (en) * 2008-11-25 2014-11-11 Baxter Healthcare Sa Method for production of pH stable enveloped viruses
CN101524538A (zh) 2009-03-26 2009-09-09 成都康华生物制品有限公司 一种流感-大流行流感二价联合疫苗及其制备方法
JP2013520172A (ja) 2010-02-18 2013-06-06 モウント シナイ スクール オフ メディシネ インフルエンザウイルス疾患の予防及び治療で用いるためのワクチン
MX338758B (es) 2010-03-08 2016-04-29 Celltrion Inc Anticuerpos monoclonales humanos, derivados de celulas b humanas, y que tienen actividad neutralizante contra el virus de la influenza a.
AU2011235220B2 (en) 2010-03-30 2016-03-10 Mount Sinai School Of Medicine Influenza virus vaccines and uses thereof
KR101960928B1 (ko) 2011-04-21 2019-07-17 올로지 바이오서비시즈, 인크. 백신으로부터 항원을 단리하고 정량하기 위한 방법
CN102406931B (zh) * 2011-11-25 2014-02-05 成都康华生物制品有限公司 大流行流感病毒裂解疫苗
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CN108348618B (zh) * 2015-09-29 2021-06-15 大日本住友制药株式会社 腺嘌呤缀合物化合物及其作为疫苗佐剂的用途
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JP7403733B2 (ja) 2017-09-04 2023-12-25 国立感染症研究所長 インフルエンザｈａスプリットワクチンの製造方法
US12059462B2 (en) * 2018-07-23 2024-08-13 Japan As Represented By Director General Of National Institute Of Infectious Diseases Composition containing influenza vaccine
US20220072126A1 (en) * 2018-12-26 2022-03-10 Sumitomo Dainippon Pharma Co., Ltd. Preparation including vaccine adjuvant
EP3930750A4 (en) * 2019-02-28 2023-01-18 Novavax, Inc. PROCEDURES TO PREVENT DISEASE OR DISORDER FROM RSV INFECTION

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JP2016516090A (ja) 2013-03-29 2016-06-02 セルトリオン・インコーポレイテッド ２以上のインフルエンザａウイルス中和結合分子を含む組成物

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EA202192398A1 (ru) 2021-11-23
CA3132578A1 (en) 2020-09-10
AU2020233456A1 (en) 2021-10-07
MY208974A (en) 2025-06-14
MX2021010685A (es) 2021-12-10
IL285984A (en) 2021-10-31
EP3936147A1 (en) 2022-01-12
EP3936147A4 (en) 2022-09-28
US12491240B2 (en) 2025-12-09
PH12021552094A1 (en) 2022-05-30
BR112021017310A2 (enExample) 2021-11-16
WO2020179797A1 (ja) 2020-09-10
BR112021017310A8 (pt) 2022-12-06
JPWO2020179797A1 (enExample) 2020-09-10
SG11202109566XA (en) 2021-10-28
US20220152191A1 (en) 2022-05-19
CN114096273A (zh) 2022-02-25
JP7545955B2 (ja) 2024-09-05

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