KR20210124233A - 다차원 세포 배양 장치 및 방법 - Google Patents

다차원 세포 배양 장치 및 방법 Download PDF

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Publication number
KR20210124233A
KR20210124233A KR1020217024605A KR20217024605A KR20210124233A KR 20210124233 A KR20210124233 A KR 20210124233A KR 1020217024605 A KR1020217024605 A KR 1020217024605A KR 20217024605 A KR20217024605 A KR 20217024605A KR 20210124233 A KR20210124233 A KR 20210124233A
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South Korea
Prior art keywords
cells
cell
culture
tissueoids
base matrix
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KR1020217024605A
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English (en)
Korean (ko)
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쿤두 프라부다 쿠마르
다스 아비지트
아로라 누푸르 메흐로트라
마주움다르 사움야브라타
바루 암비카
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프레마스 바이오테크 프라이빗 리미티드
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Publication of KR20210124233A publication Critical patent/KR20210124233A/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020217024605A 2019-01-04 2020-01-04 다차원 세포 배양 장치 및 방법 KR20210124233A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN201911000546 2019-01-04
IN201911000546 2019-01-04
PCT/IN2020/050011 WO2020141559A2 (en) 2019-01-04 2020-01-04 Device and method for multidimensional cell culture

Publications (1)

Publication Number Publication Date
KR20210124233A true KR20210124233A (ko) 2021-10-14

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KR1020217024605A KR20210124233A (ko) 2019-01-04 2020-01-04 다차원 세포 배양 장치 및 방법

Country Status (5)

Country Link
EP (1) EP3906299A4 (ja)
JP (1) JP2022516905A (ja)
KR (1) KR20210124233A (ja)
CA (1) CA3125540A1 (ja)
WO (1) WO2020141559A2 (ja)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266476A (en) * 1985-06-18 1993-11-30 Yeda Research & Development Co., Ltd. Fibrous matrix for in vitro cell cultivation
US4833083A (en) * 1987-05-26 1989-05-23 Sepragen Corporation Packed bed bioreactor
DE69633189T2 (de) * 1995-10-06 2005-08-11 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Fester Träger zur Verwendung in der Zellkultivierung, insbesondere für die Kultivierung von Leberzellen, Bioreaktor, welcher den festen Träger enthält, und die Verwendung davon in einem biologisch-künstlichen Lebersystem
US5827729A (en) * 1996-04-23 1998-10-27 Advanced Tissue Sciences Diffusion gradient bioreactor and extracorporeal liver device using a three-dimensional liver tissue
US8367410B2 (en) * 2003-06-20 2013-02-05 Massachusetts Institute Of Technology Application of electrical stimulation for functional tissue engineering in vitro and in vivo
US7682822B2 (en) * 2006-03-31 2010-03-23 Aastrom Biosciences, Inc. Ex vivo generated tissue system
EP2183353B1 (en) * 2007-08-22 2015-04-29 ProBioGen AG Culture system and method for immunogenicity and immunofunction testing in vitro
GB0815427D0 (en) * 2008-08-22 2008-10-01 Capsant Neurotechnologies S A Device
GB2466481B (en) * 2008-12-17 2013-05-29 Ucl Business Plc Improvements in or relating to growing cells
CA2919486C (en) * 2013-08-02 2021-11-02 University Of South Florida Three dimensional fibrous scaffolds for cell culture
US11447743B2 (en) * 2014-04-22 2022-09-20 Nippon Shokubai Co., Ltd. Cell culture substrate comprising fluorine-containing polymer on its surface
EP3377225A4 (en) * 2015-11-18 2019-07-03 President and Fellows of Harvard College CARTRIDGE-BASED SYSTEMS FOR LONG-TERM CULTIVATION OF CELLULAR AGGREGATES
CN109496236A (zh) * 2016-06-06 2019-03-19 普拉里斯坦有限公司 改变的粘附基质细胞及其产生和使用方法

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Publication number Publication date
CA3125540A1 (en) 2020-07-09
WO2020141559A2 (en) 2020-07-09
WO2020141559A3 (en) 2020-09-17
EP3906299A4 (en) 2022-10-19
EP3906299A2 (en) 2021-11-10
JP2022516905A (ja) 2022-03-03

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