KR20210068036A - Cd73 억제제 및 그의 제약 용도 - Google Patents
Cd73 억제제 및 그의 제약 용도 Download PDFInfo
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- KR20210068036A KR20210068036A KR1020217010568A KR20217010568A KR20210068036A KR 20210068036 A KR20210068036 A KR 20210068036A KR 1020217010568 A KR1020217010568 A KR 1020217010568A KR 20217010568 A KR20217010568 A KR 20217010568A KR 20210068036 A KR20210068036 A KR 20210068036A
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- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
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- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
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- C—CHEMISTRY; METALLURGY
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/167—Purine radicals with ribosyl as the saccharide radical
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02P20/00—Technologies relating to chemical industry
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- Genetics & Genomics (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
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- Urology & Nephrology (AREA)
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811057145.X | 2018-09-11 | ||
CN201811057145.XA CN110885352B (zh) | 2018-09-11 | 2018-09-11 | Cd73抑制剂及其药学应用 |
US201862773267P | 2018-11-30 | 2018-11-30 | |
US62/773,267 | 2018-11-30 | ||
PCT/CA2019/051268 WO2020051686A1 (en) | 2018-09-11 | 2019-09-10 | Cd73 inhibitors and pharmaceutical uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20210068036A true KR20210068036A (ko) | 2021-06-08 |
Family
ID=69745519
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020217010568A KR20210068036A (ko) | 2018-09-11 | 2019-09-10 | Cd73 억제제 및 그의 제약 용도 |
Country Status (6)
Country | Link |
---|---|
JP (1) | JP7192130B2 (zh) |
KR (1) | KR20210068036A (zh) |
CN (2) | CN110885352B (zh) |
BR (1) | BR112021004435A2 (zh) |
CA (1) | CA3111450A1 (zh) |
WO (1) | WO2020051686A1 (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11530234B2 (en) | 2018-09-11 | 2022-12-20 | Risen (Suzhou) Pharma Tech Co., Ltd. | CD73 inhibitors and pharmaceutical uses thereof |
TWI821559B (zh) * | 2019-04-28 | 2023-11-11 | 大陸商上海和譽生物醫藥科技有限公司 | 一種cd73抑制劑,其製備方法和應用 |
CN116546990A (zh) * | 2020-11-25 | 2023-08-04 | 润佳(苏州)医药科技有限公司 | Cd73抑制剂及其药学应用 |
US20240024346A1 (en) * | 2020-11-25 | 2024-01-25 | Risen (Suzhou) Pharma Tech Co., Ltd. | Cd73 inhibitors and pharmaceutical uses thereof |
WO2023201267A1 (en) | 2022-04-13 | 2023-10-19 | Gilead Sciences, Inc. | Combination therapy for treating trop-2 expressing cancers |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015043492A1 (en) * | 2013-09-26 | 2015-04-02 | Sunshine Lake Pharma Co., Ltd. | Substituted urea derivatives and uses thereof in medicine |
HUE063388T2 (hu) * | 2016-01-08 | 2024-01-28 | Arcus Biosciences Inc | Ekto-5'-nukleotidáz modulátorok és ezek alkalmazása |
EP3541396A4 (en) * | 2016-11-18 | 2020-07-22 | Arcus Biosciences, Inc. | CD73-MEDIATED IMMUNOSUPPRESSION INHIBITORS |
-
2018
- 2018-09-11 CN CN201811057145.XA patent/CN110885352B/zh active Active
-
2019
- 2019-09-10 WO PCT/CA2019/051268 patent/WO2020051686A1/en active Search and Examination
- 2019-09-10 KR KR1020217010568A patent/KR20210068036A/ko active Search and Examination
- 2019-09-10 CA CA3111450A patent/CA3111450A1/en active Pending
- 2019-09-10 JP JP2021537450A patent/JP7192130B2/ja active Active
- 2019-09-10 BR BR112021004435-3A patent/BR112021004435A2/pt unknown
- 2019-09-10 CN CN201980059602.5A patent/CN112771061B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
JP7192130B2 (ja) | 2022-12-19 |
CN110885352B (zh) | 2023-02-24 |
BR112021004435A2 (pt) | 2021-05-25 |
CN110885352A (zh) | 2020-03-17 |
JP2021527139A (ja) | 2021-10-11 |
CN112771061A (zh) | 2021-05-07 |
WO2020051686A1 (en) | 2020-03-19 |
CA3111450A1 (en) | 2020-03-19 |
CN112771061B (zh) | 2022-06-17 |
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