KR20210060559A - 관절 전달에 적합한 약학 조성물 및 관절통 치료에서의 이의 용도 - Google Patents

관절 전달에 적합한 약학 조성물 및 관절통 치료에서의 이의 용도 Download PDF

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Publication number
KR20210060559A
KR20210060559A KR1020217011328A KR20217011328A KR20210060559A KR 20210060559 A KR20210060559 A KR 20210060559A KR 1020217011328 A KR1020217011328 A KR 1020217011328A KR 20217011328 A KR20217011328 A KR 20217011328A KR 20210060559 A KR20210060559 A KR 20210060559A
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South Korea
Prior art keywords
pharmaceutical composition
μmol
joint
amount
phospholipids
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Ceased
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KR1020217011328A
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English (en)
Korean (ko)
Inventor
윈-롱 청
쉬에-팡 쉬
포-춘 창
로 창
Original Assignee
티엘씨 바이오파머슈티컬즈 인코포레이티드
타이완 리포좀 캄파니 리미티드
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Application filed by 티엘씨 바이오파머슈티컬즈 인코포레이티드, 타이완 리포좀 캄파니 리미티드 filed Critical 티엘씨 바이오파머슈티컬즈 인코포레이티드
Publication of KR20210060559A publication Critical patent/KR20210060559A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020217011328A 2018-09-16 2019-09-16 관절 전달에 적합한 약학 조성물 및 관절통 치료에서의 이의 용도 Ceased KR20210060559A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862731941P 2018-09-16 2018-09-16
US62/731,941 2018-09-16
PCT/US2019/051247 WO2020056399A1 (en) 2018-09-16 2019-09-16 Pharmaceutical compositions suitable for articular delivery and use thereof in treatment of joint pain

Publications (1)

Publication Number Publication Date
KR20210060559A true KR20210060559A (ko) 2021-05-26

Family

ID=68084954

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020217011328A Ceased KR20210060559A (ko) 2018-09-16 2019-09-16 관절 전달에 적합한 약학 조성물 및 관절통 치료에서의 이의 용도

Country Status (15)

Country Link
US (1) US12208104B2 (https=)
EP (1) EP3849522A1 (https=)
JP (1) JP7634476B2 (https=)
KR (1) KR20210060559A (https=)
CN (1) CN112702993A (https=)
AU (1) AU2019339528B2 (https=)
BR (1) BR112021004880A2 (https=)
CA (1) CA3112234A1 (https=)
CL (1) CL2021000627A1 (https=)
IL (1) IL281513A (https=)
MX (1) MX2021003030A (https=)
SG (1) SG11202102400PA (https=)
TW (1) TWI843751B (https=)
WO (1) WO2020056399A1 (https=)
ZA (1) ZA202101688B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3187955A1 (en) 2020-08-05 2022-02-10 Sheue-Fang Shih Pharmaceutical composition of intra-articular corticosteroid for pain control
WO2024230404A1 (zh) * 2023-05-05 2024-11-14 中南大学湘雅医院 一种治疗关节疼痛的氢氧化镁纳米粒、其制备方法及应用
TW202519194A (zh) * 2023-11-03 2025-05-16 台灣微脂體股份有限公司 用於疼痛控制之關節內皮質類固醇的微脂體組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050152962A1 (en) * 2002-06-12 2005-07-14 Metselaar Josbert M. Composition for treatment of inflammatory disorders
EP1371362A1 (en) * 2002-06-12 2003-12-17 Universiteit Utrecht Holding B.V. Composition for treatment of inflammatory disorders
DK2797601T3 (en) 2012-02-10 2018-06-14 Taiwan Liposome Co Ltd PHARMACEUTICAL COMPOSITIONS FOR REDUCING COMPLICATIONS BY Ocular steroid
RU2677658C2 (ru) * 2012-07-05 2019-01-18 Тайвэн Липосом Ко, Лтд. Способы лечения артрита

Also Published As

Publication number Publication date
TWI843751B (zh) 2024-06-01
JP7634476B2 (ja) 2025-02-21
US20210338688A1 (en) 2021-11-04
CL2021000627A1 (es) 2021-09-10
BR112021004880A2 (pt) 2021-06-01
IL281513A (en) 2021-04-29
SG11202102400PA (en) 2021-04-29
CN112702993A (zh) 2021-04-23
WO2020056399A1 (en) 2020-03-19
US12208104B2 (en) 2025-01-28
JP2022500364A (ja) 2022-01-04
TW202023569A (zh) 2020-07-01
ZA202101688B (en) 2024-06-26
MX2021003030A (es) 2021-05-27
AU2019339528A1 (en) 2021-04-15
AU2019339528B2 (en) 2025-01-30
CA3112234A1 (en) 2020-03-19
EP3849522A1 (en) 2021-07-21

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