KR20210053881A - 살리노마이신을 포함하는 폴리머 나노입자 - Google Patents

살리노마이신을 포함하는 폴리머 나노입자 Download PDF

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Publication number
KR20210053881A
KR20210053881A KR1020217004716A KR20217004716A KR20210053881A KR 20210053881 A KR20210053881 A KR 20210053881A KR 1020217004716 A KR1020217004716 A KR 1020217004716A KR 20217004716 A KR20217004716 A KR 20217004716A KR 20210053881 A KR20210053881 A KR 20210053881A
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South Korea
Prior art keywords
peg
cancer
poly
pharmaceutical composition
pla
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Ceased
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KR1020217004716A
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English (en)
Korean (ko)
Inventor
서렌더 카르반다
제임스 힐
시리쉬 아파조슐란
마크 로젠버그
하팔 싱
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힐스트림 바이오파마 인크.
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Publication of KR20210053881A publication Critical patent/KR20210053881A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020217004716A 2018-07-18 2019-07-18 살리노마이신을 포함하는 폴리머 나노입자 Ceased KR20210053881A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862699963P 2018-07-18 2018-07-18
US62/699,963 2018-07-18
PCT/US2019/042382 WO2020018778A1 (en) 2018-07-18 2019-07-18 Polymeric nanoparticles comprising salinomycin

Publications (1)

Publication Number Publication Date
KR20210053881A true KR20210053881A (ko) 2021-05-12

Family

ID=67704555

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020217004716A Ceased KR20210053881A (ko) 2018-07-18 2019-07-18 살리노마이신을 포함하는 폴리머 나노입자

Country Status (8)

Country Link
US (1) US20200046648A1 (https=)
EP (1) EP3823589A1 (https=)
JP (1) JP2021530504A (https=)
KR (1) KR20210053881A (https=)
CN (1) CN113164375A (https=)
AU (1) AU2019307629A1 (https=)
CA (1) CA3105731A1 (https=)
WO (1) WO2020018778A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3186633A1 (en) * 2020-06-30 2022-01-06 Hillstream Biopharma Inc. Nanoparticles and methods of manufacture thereof
WO2022251844A1 (en) * 2021-05-25 2022-12-01 Hillstream Biopharma, Inc. Polymeric nanoparticles comprising chemotherapeutic compounds and related methods
CN116570584B (zh) * 2023-05-08 2025-02-18 广州白云山医药集团股份有限公司白云山制药总厂 盐霉素在制备降尿酸和/或治疗高尿酸血症的药物中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060165987A1 (en) 2002-04-05 2006-07-27 Patrice Hildgen Stealthy polymeric biodegradable nanospheres and uses thereof
AU2006278718B2 (en) 2005-08-03 2010-10-07 Secura Bio Inc. Use of HDAC inhibitors for the treatment of myeloma
KR101445405B1 (ko) 2006-07-28 2014-09-26 가부시키가이샤 브리지스톤 상간 영역을 갖는 중합체성 코어-쉘 나노입자
US20080081075A1 (en) 2006-10-02 2008-04-03 National Tsing Hua University Multifunctional mixed micelle of graft and block copolymers and preparation thereof
US9149426B2 (en) 2012-02-15 2015-10-06 University Of Tennessee Research Foundation Nanoparticle composition and methods to make and use the same
EP3778696A1 (en) 2012-04-23 2021-02-17 NanoProteagen Ltd. Polymeric nanoparticles and a process of preparation thereof
WO2018049155A1 (en) * 2016-09-08 2018-03-15 Dana-Farber Cancer Institute, Inc. Compositions comprising polymeric nanoparticles and mcl-1 antagonists
MY210233A (en) * 2017-10-11 2025-09-04 Illustris Pharmaceuticals Inc Methods and compositions for topical delivery
WO2019104001A1 (en) * 2017-11-22 2019-05-31 Hillstream Biopharma Inc. Polymeric nanoparticles comprising bortezomib

Also Published As

Publication number Publication date
AU2019307629A1 (en) 2021-02-18
US20200046648A1 (en) 2020-02-13
WO2020018778A1 (en) 2020-01-23
JP2021530504A (ja) 2021-11-11
CN113164375A (zh) 2021-07-23
CA3105731A1 (en) 2020-01-23
EP3823589A1 (en) 2021-05-26

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