KR20210020946A - 암을 치료하기 위한 물질 및 방법 - Google Patents

암을 치료하기 위한 물질 및 방법 Download PDF

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KR20210020946A
KR20210020946A KR1020207038042A KR20207038042A KR20210020946A KR 20210020946 A KR20210020946 A KR 20210020946A KR 1020207038042 A KR1020207038042 A KR 1020207038042A KR 20207038042 A KR20207038042 A KR 20207038042A KR 20210020946 A KR20210020946 A KR 20210020946A
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cells
csf
nucleic acid
polypeptide
cell
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사드 제이. 켄데리안
로잘리 엠. 스터너
미셸 제이. 콕스
레오나 세이크무라
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메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치
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KR1020207038042A 2018-06-01 2019-05-31 암을 치료하기 위한 물질 및 방법 Withdrawn KR20210020946A (ko)

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Application Number Priority Date Filing Date Title
US201862679348P 2018-06-01 2018-06-01
US62/679,348 2018-06-01
US201862753485P 2018-10-31 2018-10-31
US62/753,485 2018-10-31
PCT/US2019/034900 WO2019232370A1 (en) 2018-06-01 2019-05-31 Materials and methods for treating cancer

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US (1) US20210214723A1 (https=)
EP (1) EP3801563B1 (https=)
JP (1) JP7411578B2 (https=)
KR (1) KR20210020946A (https=)
CN (1) CN112512533A (https=)
AU (1) AU2019277660A1 (https=)
BR (1) BR112020024601A2 (https=)
CA (1) CA3101991A1 (https=)
ES (1) ES2959645T3 (https=)
MX (1) MX2020013017A (https=)
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EP3691663A4 (en) 2017-10-02 2021-08-18 Humanigen, Inc. METHODS OF TREATMENT OF TOXICITY ASSOCIATED WITH IMMUNOTHERAPIES USING A GM-CSF ANTAGONIST
US11130805B2 (en) 2017-10-02 2021-09-28 Humanigen, Inc. Methods of treating CART-T cell therapy-induced neuroinflammation using a GM-CSF antagonist
US10899831B2 (en) 2017-10-02 2021-01-26 Humanigen, Inc. Method of reducing the level of non-GM-CSF cytokines/chemokines in immunotherapy-related toxicity
US10927168B2 (en) 2017-10-02 2021-02-23 Humanicen, Inc. Method of reducing tumor relapse rate in immunotherapy by administration of lenzilumab
SG11202102317PA (en) * 2018-09-10 2021-04-29 Humanigen Inc Methods of treating immunotherapy-related toxicity using a gm-csf antagonist
US12264189B2 (en) 2018-10-31 2025-04-01 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
SG11202103589XA (en) * 2018-10-31 2021-05-28 Humanigen Inc Materials and methods for treating cancer
WO2020092736A1 (en) 2018-10-31 2020-05-07 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
CN113088540B (zh) * 2020-01-08 2024-12-06 上海交通大学医学院附属瑞金医院 一种gm-csf敲低的t细胞及其用途
JP2023542539A (ja) * 2020-09-24 2023-10-10 ザ ジャクソン ラボラトリー 免疫細胞療法を評価するためのヒト化マウスモデル
CN114934071B (zh) * 2021-04-30 2023-10-17 四川大学华西医院 一种表达免疫调节因子的car载体及其应用

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PH12013501201A1 (en) * 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
LT4461308T (lt) 2012-07-13 2025-06-10 The Trustees Of The University Of Pennsylvania Car priešnavikinio aktyvumo toksiškumo valdymas
UY35468A (es) * 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
WO2015066262A1 (en) 2013-11-04 2015-05-07 Trustees Of Dartmouth College Methods for preventing toxicity of adoptive cell therapy
WO2017059796A1 (en) * 2015-10-08 2017-04-13 Shanghai Sidansai Biotechnology Co., Ltd Activation and expansion of t cells
CN116850305A (zh) * 2016-05-06 2023-10-10 朱诺治疗学股份有限公司 基因工程化细胞及其制备方法
CN107746831B (zh) * 2017-11-07 2019-04-23 南京北恒生物科技有限公司 具有化疗药物抗性的通用型cart/tcrt细胞及其构建方法

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US20210214723A1 (en) 2021-07-15
AU2019277660A1 (en) 2021-01-21
WO2019232370A1 (en) 2019-12-05
CA3101991A1 (en) 2019-12-05
CN112512533A (zh) 2021-03-16
BR112020024601A2 (pt) 2021-04-06
ES2959645T3 (es) 2024-02-27
EP3801563A1 (en) 2021-04-14
EP3801563B1 (en) 2023-07-12
JP2021525519A (ja) 2021-09-27

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