KR20210019116A - 카복시아미도트리아졸 오로테이트를 사용하여 화학치료제 및 표적화된 약물에 대해 내성을 획득한 암을 치료하기 위한 방법 및 조성물 - Google Patents
카복시아미도트리아졸 오로테이트를 사용하여 화학치료제 및 표적화된 약물에 대해 내성을 획득한 암을 치료하기 위한 방법 및 조성물 Download PDFInfo
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- KR20210019116A KR20210019116A KR1020217003925A KR20217003925A KR20210019116A KR 20210019116 A KR20210019116 A KR 20210019116A KR 1020217003925 A KR1020217003925 A KR 1020217003925A KR 20217003925 A KR20217003925 A KR 20217003925A KR 20210019116 A KR20210019116 A KR 20210019116A
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| US13/986,103 | 2013-04-01 | ||
| PCT/US2014/032253 WO2014165412A2 (en) | 2013-04-01 | 2014-03-28 | Methods and compositions for treating cancers having acquired resistance to chemotherapeutic and targeted drugs using carboxyamidotriazole orotate |
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| KR1020157022953A Abandoned KR20160026824A (ko) | 2013-04-01 | 2014-03-28 | 카복시아미도트리아졸 오로테이트를 사용하여 화학치료제 및 표적화된 약물에 대해 내성을 획득한 암을 치료하기 위한 방법 및 조성물 |
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| US11186640B2 (en) * | 2014-07-31 | 2021-11-30 | The University Of Western Australia | Method for the identification of immunotherapy-drug combinations using a network approach |
| EP3423105B1 (en) | 2016-03-02 | 2021-05-05 | Eisai R&D Management Co., Ltd. | Eribulin-based antibody-drug conjugates and methods of use |
| ES2928773T3 (es) | 2017-01-17 | 2022-11-22 | Heparegenix Gmbh | Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos |
| CN107890467A (zh) * | 2017-11-24 | 2018-04-10 | 中国医学科学院基础医学研究所 | 干扰能量代谢的药物在胰腺癌复发中的应用 |
| US20220168276A1 (en) * | 2020-08-05 | 2022-06-02 | Tactical Therapeotics Inc. | Mehods and Compositions for Treating SARS-CoV-2 Infection using Carboxyamidotriazole Orotate |
| WO2024208247A1 (zh) * | 2023-04-04 | 2024-10-10 | 广东银珠医药科技有限公司 | 羧胺三唑在制备治疗肿瘤骨转移的药物中的用途 |
| WO2024235217A1 (zh) * | 2023-05-15 | 2024-11-21 | 广东银珠医药科技有限公司 | 一种抗肺癌联合用药物及其应用 |
| CN119971050A (zh) * | 2023-11-10 | 2025-05-13 | 广东银珠医药科技有限公司 | 羧胺三唑与化疗药的组合物及联用治疗实体瘤的用途 |
| CN120817906A (zh) * | 2024-04-12 | 2025-10-21 | 广东银珠医药科技有限公司 | 一种三氮唑类化合物及其用途 |
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| US8034823B2 (en) * | 2005-02-22 | 2011-10-11 | Savvipharm Inc | Method of increasing drug oral bioavailability and compositions of less toxic orotate salts |
| US7750018B2 (en) * | 2006-12-06 | 2010-07-06 | Tactical Therapeutics, Inc | Use of carboxiamidotriazole (CAI) orotate in macular degeneration |
| CN101801983B (zh) * | 2007-08-13 | 2014-01-29 | 辛塔制药公司 | 调控hsp90活性的三唑化合物 |
| CN101669941B (zh) * | 2008-09-09 | 2012-11-07 | 中国医学科学院基础医学研究所 | 一种联合用药治疗恶性肿瘤的方法以及抗恶性肿瘤的药物 |
| MX2012002730A (es) * | 2009-09-04 | 2012-07-20 | Tactical Therapeutics Inc | Nuevas composiciones y procesos para preparar formulaciones de 1,2,3-triazoles 5-amino o amino sustituidos y triazol orotato. |
| US8877785B2 (en) * | 2009-09-04 | 2014-11-04 | Tactical Therapeutics Inc | Methods and compositions for enhancing sensitivity of cytotoxic drugs with timely combinatorial therapy with carboxyamidotriazole orotate |
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| ZA201506037B (en) | 2021-09-29 |
| JP6410795B2 (ja) | 2018-10-24 |
| CA2902144A1 (en) | 2014-10-09 |
| CN105120663A (zh) | 2015-12-02 |
| WO2014165412A2 (en) | 2014-10-09 |
| HK1214921A1 (zh) | 2016-08-12 |
| EP2981169B1 (en) | 2021-05-05 |
| CN105120663B (zh) | 2017-08-04 |
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