KR20210014224A - 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물 - Google Patents

혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물 Download PDF

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KR20210014224A
KR20210014224A KR1020217003129A KR20217003129A KR20210014224A KR 20210014224 A KR20210014224 A KR 20210014224A KR 1020217003129 A KR1020217003129 A KR 1020217003129A KR 20217003129 A KR20217003129 A KR 20217003129A KR 20210014224 A KR20210014224 A KR 20210014224A
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alk1
polypeptide
leu
val
angiogenesis
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아시아 그린버그
존 크노프
라빈드라 쿠마르
로버트 스콧 퍼살
자스비르 씨라
크리스티안 피에트라스
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악셀레론 파마 인코포레이티드
루드비히 인스티튜트 포우 캔써 리써치 엘티디.
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Priority to KR1020217028926A priority Critical patent/KR20210113446A/ko
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    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

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KR1020217003129A 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물 Withdrawn KR20210014224A (ko)

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Application Number Priority Date Filing Date Title
KR1020217028926A KR20210113446A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5016808P 2008-05-02 2008-05-02
US61/050,168 2008-05-02
US14413109P 2009-01-12 2009-01-12
US61/144,131 2009-01-12
PCT/US2009/002699 WO2009134428A2 (en) 2008-05-02 2009-05-01 Methods and compositions for modulating angiogenesis and pericyte composition

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KR1020207018412A Division KR20200079567A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물

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KR1020217003129A Withdrawn KR20210014224A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
KR1020107027046A Ceased KR20110031908A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
KR1020187006926A Ceased KR20180029111A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
KR1020217028926A Ceased KR20210113446A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
KR1020197032900A Withdrawn KR20190128254A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
KR1020197008836A Withdrawn KR20190037355A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
KR1020207018412A Withdrawn KR20200079567A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
KR1020177002063A Ceased KR20170012595A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물

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KR1020187006926A Ceased KR20180029111A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
KR1020217028926A Ceased KR20210113446A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
KR1020197032900A Withdrawn KR20190128254A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
KR1020197008836A Withdrawn KR20190037355A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
KR1020207018412A Withdrawn KR20200079567A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
KR1020177002063A Ceased KR20170012595A (ko) 2008-05-02 2009-05-01 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물

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US (4) US8158584B2 (cg-RX-API-DMAC7.html)
EP (2) EP3398966A1 (cg-RX-API-DMAC7.html)
JP (5) JP5719766B2 (cg-RX-API-DMAC7.html)
KR (8) KR20210014224A (cg-RX-API-DMAC7.html)
CN (2) CN105963695A (cg-RX-API-DMAC7.html)
AU (5) AU2009241755B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0911853A8 (cg-RX-API-DMAC7.html)
CA (1) CA2723449C (cg-RX-API-DMAC7.html)
MX (2) MX391905B (cg-RX-API-DMAC7.html)
TW (3) TW201609138A (cg-RX-API-DMAC7.html)
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KR20170012582A (ko) 2006-11-02 2017-02-02 악셀레론 파마 인코포레이티드 Alk1 수용체 및 리간드 길항제 및 그의 용도
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EP2291401A2 (en) * 2008-05-15 2011-03-09 Acceleron Pharma, Inc. Antagonists of bmp9, bmp10, alk1 and other alk1 ligands, and uses thereof
WO2013116781A1 (en) * 2012-02-02 2013-08-08 Acceleron Pharma Inc. Alk1 antagonists and their uses in treating renal cell carcinoma
US9809636B2 (en) 2012-04-06 2017-11-07 Acceleron Pharma Inc. Methods for increasing red blood cell levels comprising administering BMP9
HK1225742A1 (zh) * 2013-08-22 2017-09-15 Acceleron Pharma, Inc. TGF-β受体II型变体及其用途
JP2016036322A (ja) * 2014-08-11 2016-03-22 日本化薬株式会社 血管新生因子と結合するキメラタンパク質
CN113683708A (zh) 2015-04-06 2021-11-23 阿塞勒隆制药公司 单臂i型和ii型受体融合蛋白和其用途
EP3280435B1 (en) * 2015-04-06 2021-06-02 Acceleron Pharma Inc. Tgf-beta superfamily type i and type ii receptor heteromultimers and uses thereof
CN110317264B (zh) * 2015-11-10 2022-10-11 孙嘉琳 一种抗肿瘤蛋白内皮抑素的衍生物
AU2017296040C1 (en) 2016-07-15 2023-06-22 Acceleron Pharma Inc. Compositions and methods for treating pulmonary hypertension
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AU2018358804A1 (en) * 2017-11-02 2020-04-09 Bayer Aktiengesellschaft Bispecific antibodies binding ALK-1 and BMPR-2
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CN114028541A (zh) * 2021-05-21 2022-02-11 中山大学 Gdf2在制备改善肿瘤异常血管的药物中的用途
CN121079328A (zh) * 2023-01-18 2025-12-05 开拓药业(广东)有限公司 抗alk-1抗体及其用途
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