KR20210000700A - Compositions comprising phlorotannin for improving female sexual dysfunction - Google Patents

Abstract

The present invention relates to a composition having an effect of improving the female sexual function by applying the same to the female vagina. More specifically, the present invention relates to a composition and related products for use in improving the female sexual function by applying the composition containing a phlorotannin compound as an active component to inside and outside the vagina in a form of a spray or the like.

Description

Composition for improving female sexual function containing fluorotannin as an active ingredient {COMPOSITIONS COMPRISING PHLOROTANNIN FOR IMPROVING FEMALE SEXUAL DYSFUNCTION}

The present invention relates to a composition having an effect of improving the sexual function of a woman by applying it to the vagina of a woman. In more detail, the present invention relates to a composition for improving sexual function of a woman and related products by applying a composition containing a fluorotannin compound as an active ingredient in and out of the vagina in the form of a spray.

Female Sexual Dysfunction (FSD) refers to various disorders or impairments of sexual function, lack of desire for sexual activity, repeated failure to reach or maintain sexual arousal, reaching sufficient orgasm following excitement. Not possible, including pain during intercourse. It is estimated that 43% of women in the United States suffer from sexual dysfunction, and it is a very serious problem that negatively affects gender relationships for more and more women. Frustration, including a tendency to stop having sex, affects many women at a young age or after menopause.

Female sexual dysfunction and sexual dysfunction can be divided into the following 6 domains.

* Desire

* Arousal

* Lubrication

* Orgasm

* Satisfaction

* Pain

It is difficult to expect a satisfactory effect with fragmentary approaches, as it has been investigated that female sexual function consisting of such various aspects is determined by the interaction of different cognitive, emotional, and organic factors. For example, after discovering the effect of promoting erectile function in men, which is associated with vascular activation components, studies have been conducted on the same principle in women, but failing to normalize female sexual function.

Republic of Korea Application Publication No. 2010-0029788

Although female sexual dysfunction is a symptom manifested by a combination of factors, the approaches to date use very fragmentary or invasive methods such as pharmaceutical vasodilators, hormonal drugs, and physical implant insertion by surgery, or methods with many concerns about side effects. have. Therefore, there is a demand for products that women can use safely and universally. However, it is difficult to achieve sufficient satisfaction with a substance or method that exhibits an effect on only some of the six factors of female sexual function.

Accordingly, the present inventors intend to provide materials and products that anyone can use safely and easily, can quickly exert a total effect on six factors, and can expect even a fundamental improvement effect by continuous use.

In order to achieve the above object, the present invention provides a composition for improving female sexual function comprising a fluorotannin compound as an active ingredient.

In addition, the present invention provides a product having the effect of improving female sexual function comprising the composition.

Compositions and products containing fluorotannin of the present invention as an active ingredient are natural materials, safe, easy to use, and have the effect of improving all six aspects of female sexual function. In addition, it can give a fundamental improvement effect through continuous use.

1 is a diagram explaining the effect of the present invention.

Hereinafter, the present invention will be described in detail.

Based on several previous literatures, the risk factors for causing female sexual dysfunction can be analyzed as follows.

* Depression, anxiety,

* Cardiovascular disease

* Nervous system abnormalities

* Side effects from depression treatment, hypertension treatment, etc.

* Emotional or psychological stress, especially stress related to relationships with partners

The above risk factors are factors that cause problems in the operation of the central nervous system and the local organic feedback system required for sexual activation and function completion. In more detail, it can be seen that it acts as a negative factor in the sexual activation of the densely distributed local nervous system and the vascular system, and the feedback function between the central nervous system, which is closely connected to the sexual excitement and feelings of satisfaction.

The present inventors have chosen a strategy of simultaneously activating the local nervous system and vascular system as a method for improving the feedback function. The present inventors search for natural ingredients that can contribute to the activation of the nervous system, along with the action of quickly promoting peripheral blood circulation and being directly applied to the local and vaginal areas of women among natural ingredients having absolute safety for the human body. In the meantime, it was discovered that a composition containing fluorotannin as an active ingredient could achieve this purpose. That is, it was confirmed that the composition containing fluorotannin as an active ingredient can improve the six aspects of female sexual function in total, and the present invention was completed.

When applied directly to the skin, the fluorotannin of the present invention does not cause allergies, has antibacterial and anti-inflammatory activities, and thus reduces the pain during intercourse by reducing infection and inflammation of the skin, as well as preventing damage to the vaginal wall. It also has the advantage of being able to. Also, considering that the vagina is acidic, it is resistant to acid and has excellent stability.

Therefore, a composition containing fluorotannin as an active ingredient can be prepared as a product in the form of a liquid spray or cream that is convenient for topical application and used inside and outside the vagina to improve female sexual function.

The fluorotannin contained in the composition for improving female sexual function of the present invention can be obtained by all conventional methods, can be synthesized using commercially available reagents, and can be obtained by extraction and separation from natural products, especially seaweed.

The active ingredient of the composition of the present invention can be extracted from brown algae. Eisenia galapagensis, Eisenia masonii, Ecklonia kurome, Ecklonia cava, Ecklonia stolonifera, Ecklonia maxima, Ecklonia radiata (Ecklonia radiata), Ecklonia bicyclis, Ecklonia biruncinate, Ecklonia buccinalis, Ecklonia caepaestipes, Ecklonia exas Putta (Ecklonia exasperta), Ecklonia fastigiata, Ecklonia brevipes, Ecklonia arborea, Ecklonia latifolia, Ecklonia murati ( Ecklonia muratii), Ecklonia radicosa, Ecklonia richardiana, and Ecklonia wrightii.

The fluorotannin compound, which is an active ingredient of the composition of the present invention, is particularly preferably an ecchol compound among the fluorotannin compounds. Exol-based compounds have a relatively small molecular weight and have a 3 or 5 fused ring system, and have a flat structure, so they can be easily absorbed through the skin and quickly reach the blood vessels and nervous system when applied locally. have.

The fluorotannin compound, which is an active ingredient of the composition of the present invention, may be more preferably one or more compounds selected from the compounds of Formulas 1 to 12 below.

[Formula 1]

[Formula 2]

[Formula 3]

[Formula 4]

[Formula 5]

[Formula 6]

[Formula 7]

[Formula 8]

[Formula 9]

[Formula 10]

[Formula 11]

[Formula 12]

The composition for improving female sexual function of the present invention may contain 0.1-100% by weight of the fluorotannin compound.

In addition to fluorotannin, the composition of the present invention additionally contains 0-99.9% by weight of purified water, at least one selected from components consisting of mannitol, alginic acid, fucoidan, laminaran as a carbohydrate component, and fucosterol, fucoxanthine as a lipid component. can do.

The composition for improving female sexual function of the present invention particularly has at least one fluorotannin selected from Formulas 1 to 7 (having a fused ring in which three rings are conjugated) having excellent activity related to promoting blood circulation and related to nerve activation. A more excellent effect can be exhibited when at least one fluorotannin selected from Formulas 8 to 12 having excellent activity (having a fused ring in which five rings are conjugated) is combined.

The composition for improving female sexual function of the present invention preferably comprises at least one fluorotannin selected from fluorotannins of Formulas 1 to 7 and at least one fluorotannin selected from fluorotannins of Formulas 8 to 12 by weight. If it contains 1: 10 to 10: 1, the effect may be more excellent.

More preferably, the fluorotannin contained in the composition is 0.5 to 5.0 wt% of fluorotannin of formula 1, 0.5 to 5.0 wt% of fluorotannin of formula 2, and fluorotannin of formula 3 based on the total weight of fluorotannin. 0.5 to 5% by weight of tannin, 0.5 to 5% by weight of fluorotannin of formula 4, 0.1 to 2% by weight of fluorotannin of formula 5, 0.2 to 3% by weight of fluorotannin of formula 6, fluorotannin 2 of formula 7 -30% by weight, 0.2-3% by weight of fluorotannin of formula 8, 0.2-3% by weight of fluorotannin of formula 9, 0.2-3% by weight of fluorotannin of formula 10, 0.1-2 of fluorotannin of formula 11 It may contain 0.01-1% by weight of the fluorotannin of formula 12 by weight.

The fluorotannin composition may be commercialized in the form of a liquid spray, cream, or gel. In the product, the fluorotannin composition may be contained in an amount of 0.001 to 1% by weight, preferably 0.01 to 0.5% by weight, and more preferably 0.02 to 0.2% by weight, based on the total weight of the product. When the fluorotannin compound is included in the above content, the effect of improving female sexual function is excellent.

The product for improving female sexual function of the present invention includes a fluorotannin composition and purified water, and also ethanol, glycerin, 1,2-hexanediol, vitamin, vitamin C, arginine, fragrance, ylang-ylang oil, Glycereth-26 PCA Isostearate (Emalex GPI-25) and fermented green tea extract may contain one or more selected from the group consisting of.

The product for improving female sexual function of the present invention may preferably further contain 0.001 to 1% by weight of arginine.

The daily use amount of fluorotannin contained in the composition and product for improving female sexual function of the present invention is preferably about 0.1 to 100 mg, but the amount is not limited to the above range.

Hereinafter, the present invention will be described in more detail through examples. However, the following examples are for explaining the present invention in more detail, and the scope of the present invention is not limited by the following examples. The following examples can be appropriately modified and changed by those skilled in the art within the scope of the present invention.

Preparation Example 1. Preparation of fluorotannin compound

In order to prepare a composition containing fluorotannin of the present invention as an active ingredient, it was extracted from the brown algae Ecklonia cava ( Ecklonia cava ) collected in the coast of Jeju Island by the following method.

Ecklonia cava was washed with distilled water to remove foreign substances, dried in the shade, and then crushed. 500 g of the Ecklonia cava was put in an extraction container, and a 30% by weight aqueous alcohol solution of 20 times the weight of Ecklonia was added, followed by reflux extraction at 75 to 80°C for 4 hours to obtain an extract. The extract was filtered through a 10 μm filter net, and the filtered extract was concentrated under reduced pressure in a 55° C. water bath to obtain a primary extract concentrate. The first extract concentrate was dried with a vacuum dryer at 90° C. for 8 hours or more at a pressure of 70 torr, and then pulverized to obtain 170 g of the first extract. The primary extract was dissolved in hot water at 50° C., adsorbed on an adsorption resin, washed with water, and eluted with alcohol to obtain a fluorotannin eluate. The eluate was filtered through a 1 μm filter network, and the filtered extract was concentrated under reduced pressure in a 55° C. water bath to obtain a secondary extract concentrate. The second extract concentrate was dried with a vacuum dryer at 90° C. for at least 8 hours at a pressure of 70 torr, and then pulverized to obtain 30 g of a second extract. The secondary extract was dissolved in alcohol, and filter aid (diatomaceous earth or bentonite) was added and filtered to obtain an eluate. The eluate was filtered through a 1 µm filter net, and the filtered eluate was concentrated under reduced pressure in a 55° C. water bath to obtain a concentrated solution. The concentrate was dried with a vacuum dryer at 90° C. for 8 hours or more at a pressure of 70 torr, and then pulverized to obtain 19 g of the composition.

The composition obtained above was loaded onto liquid chromatography to perform compound separation to obtain 12.4 g and 2.9 g of Fraction I and Fraction II, respectively, as a fluorotannin fraction. Each of the two fractions obtained at this time was dissolved in 60% methanol, filtered through a 0.2 μm membrane filter, and loaded on high performance liquid chromatography. In high performance liquid chromatography, HP ODS Hypersil was used as the column, distilled water and methanol were used as the solvent, and the supply of the solvent was a linear gradient from 15% to 70% methanol at a flow rate of 1.0 ml/min over 30 minutes. By walking, the compounds of formulas 1 to 7 were isolated from fraction I and the compounds of formulas 8 to 12 from fraction II. The chemical compositions (based on dry weight) of the extracted fluorotannin fractions I and II are shown in Tables 1 and 2 below.

Composition of sample (% by weight) Fraction I
Formula 1 Formula 2 Formula 3 Formula 4 Formula 5 Formula 6 Formula 7 11.5 19.1 10.4 9.2 3.7 5.8 40.3

Composition of sample (% by weight) Fraction II
Formula 8 Formula 9 Formula 10 Formula 11 Formula 12 31.1 26.5 30.5 9.9 2.0

Preparation Example 2. Preparation of a composition containing a fluorotannin compound

Compositions 1 to 5 were prepared by mixing fractions I and II in a weight ratio of 1:0 to 0:1 as shown in Table 3 below. In addition, compositions 6 to 10 were prepared by mixing at least one of the compounds of Formulas 1 to 12 isolated in Fraction I and Fraction II as shown in Table 4 below.

ingredient Composition 1 Composition 2 Composition 3 Composition 4 Composition 5 Fraction I 100 80 50 20 0 Fraction II 0 20 50 80 100 Sum 100 100 100 100 100

Unit (% by weight)

ingredient Composition 6 Composition 7 Composition 8 Composition 9 Composition 10 Formula 1 100 0 0 0 0 Formula 2 50%
Formula 4 50% 0 100 0 0 0 Formula 10 0 0 100 0 0 Formula 7 40%
Formula 10 60% 0 0 0 100 0 Formula 3 80%
Formula 11 20% 0 0 0 0 100 Sum 100 100 100 100 100

Unit (% by weight)

Examples 1 to 10. Effects of improving female sexual function of compositions containing fluorotannin compounds

The effects of improving female sexual function for the compositions of Tables 3 and 4 were evaluated.

In order to check the effect of female sexual function when the composition is sprayed into the vulva and vagina, a saline solution containing no composition (Comparative Example 1, including ethanol) and a saline solution containing 0.1 wt% of each composition 1 to 10 (ethanol Including) 300mL is prepared (Table 5), each 30mL is put into 5 small spray containers, and then provided to 55 volunteers of 31 to 59 years old women who are usually uncomfortable with their sexual life, allowing them to use freely for 4 weeks, and then FSFI (The Female Sexual Function Index: Rosen et al, Journal of Sex & Marital Therapy, 26:191-208 (2000)) was used to evaluate the effect. The FSFI consists of a total of 19 questions (see Table 6 below), and is divided into six domains: Desire, Arousal, Lubrication, Orgasm, Satisfaction, and Pain. It is composed, and 1 to 5 points can be given for each question, and the higher the score, the higher the sexual function is evaluated.

ingredient Comparative Example 1 Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Example 8 Example 9 Example 10 Composition 1 - 0.1 - - - - - - - - - Composition 2 - - 0.1 - - - - - - - - Composition 3 - - - 0.1 - - - - - - - Composition 4 - - - - 0.1 - - - - - - Composition 5 - - - - - 0.1 - - - - - Composition 6 - - - - - - 0.1 - - - - Composition 7 - - - - - - - 0.1 - - - Composition 8 - - - - - - - - 0.1 - - Composition 9 - - - - - - - - - 0.1 - Composition 10 - - - - - - - - - - 0.1 ethanol 0.95 0.95 0.95 0.95 0.95 0.95 0.95 0.95 0.95 0.95 0.95 Saline solution 99.05 98.95 98.95 98.95 98.95 98.95 98.95 98.95 98.95 98.95 98.95 Sum 100 100 100 100 100 100 100 100 100 100 100

Unit (% by weight)

Questions score 1. In the last 4 weeks, how often have you felt sexual desire or interest? 5 = almost always or always; 4 = most of the time (more than half); 3 = sometimes (about half); 2 = several times (less than half);
1 = little or never 2. How would you rate your level (degree) of sexual desire or interest over the past 4 weeks? 5 = very high; 4 = high; 3 = medium; 2 = low; 1 = very low or none at all 3. In the last 4 weeks, how often have you experienced sexual arousal during or during sexual intercourse? 0 = no sexual activity; 5 = almost always or always; 4 = most of the time (more than half); 3 = sometimes (about half); 2 = several times (less than half); 1 = little or never 4. How do you rate your level of sexual arousal during sexual activity or intercourse over the past 4 weeks? 0 = no sexual activity; 5 = very high; 4 = high; 3 = moderate; 2 = low; 1 = very low or none at all 5. How confident have you been in sexual activity or sexual excitement during the last 4 weeks? 0 = no sexual activity; 5 = very high confidence; 4 = high confidence; 3 = moderate confidence; 2 = low confidence; 1 = very low or no confidence 6. In the last 4 weeks, how often have you been satisfied with sexual arousal during sexual activity or intercourse? 0 = no sexual activity; 5 = almost always or always; 4 = most (more than half); 3 = sometimes (about half); 2 = several times (less than half); 1 = little or never 7. During the last 4 weeks, how often has lubrication (wetting) inside the vagina during sexual activity or sexual intercourse? 0 = no sexual activity; 5 = almost always or always; 4 = most (more than half); 3 = sometimes (about half); 2 = several times (less than half); 1 = little or never 8. In the last 4 weeks, how difficult was it during sexual activity or during sexual intercourse to lubricate (wet) the inside of the vagina? 0 = no sexual activity; 1 = very difficult or impossible; 2 = very difficult; 3 = difficulty; 4 = somewhat difficult; 5 = not difficult 9. In the last 4 weeks, how often did you maintain vaginal lubrication (wetting) until sexual activity or intercourse is complete? 0 = no sexual activity; 5 = almost always or always; 4 = most of the time (more than half); 3 = sometimes (about half); 2 = several times (less than half); 1 = little or never 10. In the last 4 weeks, how difficult has it been to maintain vaginal lubrication until sexual activity or sexual intercourse is complete? 0 = no sexual activity; 1 = very difficult or impossible; 2 = very difficult; 3 = difficulty; 4 = somewhat difficult; 5 = not difficult 11. In the last 4 weeks, how often did you reach orgasm during sexual stimulation or sexual intercourse (climax)? 0 = no sexual activity; 5 = almost always or always; 4 = most (more than half); 3 = sometimes (about half); 2 = several times (less than half); 1 = little or never 12. How difficult has it been to reach orgasm during the last 4 weeks of sexual stimulation or intercourse (climax)? 0 = no sexual activity; 1 = very difficult or impossible; 2 = very difficult; 3 = difficulty; 4 = somewhat difficult; 5 = not difficult 13. How satisfied were you with reaching orgasm during sexual intercourse or sexual intercourse in the last 4 weeks (climax)? 0 = no sexual activity; 5 = very satisfied; 4 = approximately satisfied; 3 = half and half satisfied, dissatisfied; 2 = approximately dissatisfied; 1 = very dissatisfied 14. How satisfied are you with the level of emotional intimacy between you and your spouse during the last 4 weeks? 0 = no sexual activity; 5 = very satisfied; 4 = approximately satisfied; 3 = half and half satisfied, dissatisfied; 2 = approximately dissatisfied; 1 = very dissatisfied 15. How satisfied have you been with your partner in the last 4 weeks? 5 = very satisfied; 4 = approximately satisfied; 3 = half and half satisfied, dissatisfied; 2 = approximately dissatisfied; 1 = very dissatisfied 16. How satisfied are you with your overall sex life in the last 4 weeks? 5 = very satisfied; 4 = approximately satisfied; 3 = half and half satisfied, dissatisfied; 2 = approximately dissatisfied; 1 = very dissatisfied 17. In the past 4 weeks, how often have you experienced discomfort or pain during vaginal insertion (during sex)? 0 = no attempt was made to intercourse; 1 = almost always or always; 2 = most (more than half); 3 = sometimes (about half); 4 = several times (less than half); 5 = little or no 18. How often have you experienced discomfort or pain after vaginal insertion (after sex) in the last 4 weeks? 0 = no attempt was made to intercourse; 1 = almost always or always; 2 = most (more than half); 3 = sometimes (about half); 4 = several times (less than half); 5 = little or no 19. How do you rate the degree (grade) of discomfort or pain during or after vaginal insertion in the last 4 weeks? 0 = No attempt was made to have sex; 1 = very high; 2 = high; 3 = moderate; 4 = low; 5 = very low or none at all

The score and full scale for each domain are calculated as in Equation 1 below using the weights for each domain in Table 7 below.

domain Question number Score range weight Desire 1,2 1-5 0.6 Arousal 3,4,5,6 0~5 0.3 Lubrication 7,8,9,10 0~5 0.3 Orgasm 11,12,13, 0~5 0.4 Satisfaction (Satisfaction) 14,15,16 1-5 0.4 Pain 17,18,19 0~5 0.4

[Equation 1]

Full Scale Score = Σ(S _i × F _i ) (i=1 to 19)

Here, Si is the sum of the scores of the items corresponding to each domain, and Fi is the weight for each domain.

The FSFI evaluation (average value for each of 5 persons) at the time of using the comparative example and each composition is shown in Table 8 below.

domain Comparative Example 1 Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Example 8 Example 9 Example 10 Desire 3.0 3.6 4.7 4.2 4.6 4.4 3.4 3.7 4.5 4.9 4.5 Arousal 2.6 4.8 5.3 5.2 5.2 5.3 4.7 5.1 5.4 5.3 5.2 Lubrication 2.8 5.1 5.7 5.3 5.5 4.3 5.2 5.5 4 5.6 5.3 Orgasm 2.9 4.1 5.4 5.3 4.9 4.6 4 4.4 4.6 5.8 5.2 Satisfaction (Satisfaction) 3.2 3.8 5.3 5.5 4.5 4.6 3.6 3.8 4.2 5.7 5.4 Pain 3.9 4.5 5.8 5.6 5.4 4.3 4.4 4.9 4.3 5.8 5.4 Total Score (Full Scale) 18.5 25.9 32.1 31.2 30.0 27.6 25.3 27.4 27 33.1 31

As a result of the evaluation, it was confirmed that when the composition of the present invention was used, female sexual function was significantly increased in all six domains. In particular, a more remarkable effect was exhibited in the case of the composition containing the compound of fraction I and the compound of fraction II.

Preparation Example 3. Preparation of a spray solution for improving female sexual function using the composition

Composition 3 and the components of Table 9 below were used to prepare a female sexual function improvement spray solution, and 30 mL each was put in a spray bottle to complete the product.

Raw material name Content (% by weight) Purified water 97.46 glycerin 1.00 1,2-hexanediol 1.00 Composition 3 0.08 Vitamin C 0.01 Arginine 0.02 Ylang Ylang Oil 0.08 Glycereth-26 PCA Isostearate (Emalex GPI-25) 0.30 Fermented Green Tea Extract 0.05 Sum 100.00

Example 11. Effects of improving female sexual function of products containing fluorotannin compounds

Table 10 shows the FSFI test results for 10 female volunteers aged 31 to 59 years old who feel uncomfortable in their usual sex life with the product prepared in Preparation Example 3. Compared to the test product using saline solution, it showed more excellent effect.

domain Example 11 Desire 5.5 Arousal 5.6 Lubrication 5.5 Orgasm 5.6 Satisfaction (Satisfaction) 5.5 Pain 5.7 Total Score (Full Scale) 33.4

As described above, the composition and product containing the fluorotannin of the present invention as an active ingredient is a natural material that is safe, easy to use, and has an effect of improving all six aspects of female sexual function, so it is useful as a composition for improving female sexual function. Can be used.

Claims (10)

A composition for improving female sexual function comprising a fluorotannin compound as an active ingredient. The composition for improving female sexual function according to claim 1, wherein the fluorotannin compound is an ecchol compound. The composition for improving female sexual function according to claim 1, wherein the fluorotannin compound is at least one selected from fluorotannins represented by the following Chemical Formulas 1 to 12.
[Formula 1]

[Formula 2]

[Formula 3]

[Formula 4]

[Formula 5]

[Formula 6]

[Formula 7]

[Formula 8]

[Formula 9]

[Formula 10]

[Formula 11]

[Formula 12]

The composition for improving female sexual function according to claim 1, wherein the composition comprises 0.1-100% by weight of the total fluorotannin compound. The method according to claim 1, wherein the composition comprises at least one selected from fluorotannins represented by Formulas 1 to 7 and at least one selected from fluorotannins represented by Formulas 8 to 12, 1:10 to 10:1 Composition for improving female sexual function, characterized in that it comprises in a weight ratio of. The method according to claim 1, wherein the fluorotannin contained in the composition is 0.5 to 5.0 wt% of fluorotannin of formula 1, 0.5 to 5.0 wt% of fluorotannin of formula 2, and flow of formula 3 based on the total weight of fluorotannin. Rotannin 0.5-5% by weight, fluorotannin of formula 4 0.5-5% by weight, fluorotannin of formula 5 0.1-2% by weight, fluorotannin of formula 6 0.2-3% by weight, fluorotannin of formula 7 2-30% by weight, 0.2-3% by weight of fluorotannin of formula 8, 0.2-3% by weight of fluorotannin of formula 9, 0.2-3% by weight of fluorotannin of formula 10, 0.1- A composition for improving female sexual function, comprising 2% by weight and 0.01-1% by weight of fluorotannin of Formula 12. The method according to claim 1, wherein the fluorotannin compound is Eisenia bicyclis, Eisenia arborea, Eisenia desmarestioides, Eisenia galapagensis, Eisenia masonii, Ecklonia kurome, Ecklonia cava, Ecklonia stolonifera, Ecklonia maxima, Ecklonia radiata, Ecklonia bicyclis Ecklonia bicyclis), Ecklonia biruncinate, Ecklonia buccinalis, Ecklonia caepaestipes, Ecklonia exasperta, Ecklonia pasti Ecklonia fastigiata, Ecklonia brevipes, Ecklonia arborea, Ecklonia latifolia, Ecklonia muratii, Ecklonia radicosa radicosa), Ecklonia richardiana, and Ecklonia wrightii. Composition for improving female sexual function, characterized in that it is extracted from at least one selected from the group consisting of. A product for improving female sexual function, characterized in that it is in the form of a liquid spray, cream, or gel containing the composition of claim 1 and purified water, and is used inside and outside the vagina of a woman. The product for improving female sexual function according to claim 8, wherein the daily amount of the fluorotannin compound contained in the product is 0.1 to 100 mg. The method according to claim 8, one selected from the group consisting of ethanol, glycerin, 1,2-hexanediol, vitamins, arginine, fragrance, ylang-ylang oil, Glycereth-26 PCA Isostearate (Emalex GPI-25) and fermented green tea extract. A product for improving female sexual function, characterized in that it further comprises the above.

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