KR20200132902A - Egfr 활성화 돌연변이를 갖는 암의 치료 방법 - Google Patents

Egfr 활성화 돌연변이를 갖는 암의 치료 방법 Download PDF

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KR20200132902A
KR20200132902A KR1020207028689A KR20207028689A KR20200132902A KR 20200132902 A KR20200132902 A KR 20200132902A KR 1020207028689 A KR1020207028689 A KR 1020207028689A KR 20207028689 A KR20207028689 A KR 20207028689A KR 20200132902 A KR20200132902 A KR 20200132902A
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inhibitor
cancer
composition
cdk
subject
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존 브이. 헤이막
모니크 닐슨
재클린 로비쇼
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보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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KR1020207028689A 2018-03-13 2019-03-13 Egfr 활성화 돌연변이를 갖는 암의 치료 방법 Ceased KR20200132902A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862642472P 2018-03-13 2018-03-13
US62/642,472 2018-03-13
PCT/US2019/022067 WO2019178239A1 (en) 2018-03-13 2019-03-13 Methods for treatment of cancers with egfr activating mutations

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KR20200132902A true KR20200132902A (ko) 2020-11-25

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KR1020207028689A Ceased KR20200132902A (ko) 2018-03-13 2019-03-13 Egfr 활성화 돌연변이를 갖는 암의 치료 방법

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US (1) US20210015819A1 (https=)
JP (2) JP7698418B2 (https=)
KR (1) KR20200132902A (https=)
CN (1) CN111867586A (https=)
WO (1) WO2019178239A1 (https=)

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CN105816437B (zh) 2016-03-29 2018-08-03 深圳市药欣生物科技有限公司 一种帕布昔利布的药物制剂及其制备方法
MX2021011948A (es) * 2019-03-29 2022-01-04 Univ Texas Compuestos con actividad antitumoral contra células cancerígenas que llevan inserciones de exon 20 effr o her2.
EP4192463A1 (en) * 2020-08-07 2023-06-14 Hope Permanente, LLC Use of cyclin-dependent kinase (cdk) inhibitors for the slowdown or prevention of biological aging
CN114306245A (zh) 2020-09-29 2022-04-12 深圳市药欣生物科技有限公司 无定形固体分散体的药物组合物及其制备方法
CN114432454B (zh) * 2022-03-21 2023-05-05 安徽大学 Plk1抑制剂在制备治疗埃博拉病毒疾病的药物中的应用
CN119137102A (zh) 2022-04-08 2024-12-13 拜奥列司治疗有限公司 Cdk9抑制剂
CN117045660A (zh) * 2022-04-22 2023-11-14 南京市儿童医院 一种plk1抑制剂在制备用于缓解肾脏纤维化药物中的用途
WO2024192141A1 (en) * 2023-03-13 2024-09-19 Dana-Farber Cancer Institute, Inc. Treatment of cancers having a drug-resistant mesenchymal cell state
WO2025245045A1 (en) * 2024-05-21 2025-11-27 The Regents Of The University Of California Methods of treating lung cancer

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BRPI0707580A2 (pt) 2006-02-10 2011-05-10 Nerviano Medical Sciences Srl combinaÇÕes compreendendo um inibidor cdk e um anticorpo do fator de crescimento ou antimitàtico
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JP2021517894A (ja) 2021-07-29
CN111867586A (zh) 2020-10-30
JP7698418B2 (ja) 2025-06-25
JP2025069282A (ja) 2025-04-30
WO2019178239A1 (en) 2019-09-19
US20210015819A1 (en) 2021-01-21

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T13-X000 Administrative time limit extension granted

St.27 status event code: U-3-3-T10-T13-oth-X000