KR20200110687A - 유전체 편집 효율을 증가시키기 위한 퀴녹살리논 화합물, 조성물, 방법 및 키트 - Google Patents

유전체 편집 효율을 증가시키기 위한 퀴녹살리논 화합물, 조성물, 방법 및 키트 Download PDF

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KR20200110687A
KR20200110687A KR1020207023672A KR20207023672A KR20200110687A KR 20200110687 A KR20200110687 A KR 20200110687A KR 1020207023672 A KR1020207023672 A KR 1020207023672A KR 20207023672 A KR20207023672 A KR 20207023672A KR 20200110687 A KR20200110687 A KR 20200110687A
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compound
formula
dna
cells
genome editing
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Korean (ko)
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수디프타 마하잔
마크 사울 와인버그
디에고 세바스티안 다스톨포
케빈 엠. 코트렐
마크 에이. 모리스
존 패트릭 맥스웰
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버텍스 파마슈티칼스 인코포레이티드
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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KR1020207023672A 2018-01-17 2019-01-16 유전체 편집 효율을 증가시키기 위한 퀴녹살리논 화합물, 조성물, 방법 및 키트 Abandoned KR20200110687A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862618385P 2018-01-17 2018-01-17
US62/618,385 2018-01-17
PCT/US2019/013785 WO2019143677A1 (en) 2018-01-17 2019-01-16 Quinoxalinone compounds, compositions, methods, and kits for increasing genome editing efficiency

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KR20200110687A true KR20200110687A (ko) 2020-09-24

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KR1020207023672A Abandoned KR20200110687A (ko) 2018-01-17 2019-01-16 유전체 편집 효율을 증가시키기 위한 퀴녹살리논 화합물, 조성물, 방법 및 키트

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US (1) US12269804B2 (https=)
EP (1) EP3740483B1 (https=)
JP (1) JP7483612B2 (https=)
KR (1) KR20200110687A (https=)
CN (1) CN111770921B (https=)
AU (1) AU2019209292B2 (https=)
BR (1) BR112020013626A2 (https=)
CA (1) CA3088791A1 (https=)
EA (1) EA202091707A1 (https=)
ES (1) ES2940786T3 (https=)
IL (1) IL276081B2 (https=)
MA (1) MA51623A (https=)
WO (1) WO2019143677A1 (https=)

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BR112022003505A2 (pt) 2019-08-27 2022-05-24 Vertex Pharma Composições e métodos para tratamento de distúrbios associados a dna repetitivo
JP2024501660A (ja) * 2020-12-21 2024-01-15 オーフス ユニバーシテット 系譜限定多能性幹細胞から得られるドーパミン作動性神経前駆細胞又はその細胞誘導体
CN112750498B (zh) * 2020-12-30 2022-06-24 同济大学 靶向逆转录引物结合位点从而抑制hiv病毒复制的方法
EP4298221A1 (en) 2021-02-26 2024-01-03 Vertex Pharmaceuticals Incorporated Compositions and methods for treatment of myotonic dystrophy type 1 with crispr/slucas9
TW202302848A (zh) 2021-02-26 2023-01-16 美商維泰克斯製藥公司 以crispr/sacas9治療第1型肌強直性營養不良之組合物及方法
CA3213117A1 (en) * 2021-03-10 2022-09-15 adMare Therapeutics Society 7-morpholino-l,6-naphthyridin-5-yl derivatives and pharmaceutical compositions thereof useful as dna-pk inhibitor
WO2023018637A1 (en) 2021-08-09 2023-02-16 Vertex Pharmaceuticals Incorporated Gene editing of regulatory elements
CN114685494B (zh) * 2022-03-16 2024-04-16 中国人民解放军军事科学院军事医学研究院 SpCas9抑制剂的合成制备方法及其应用
US20250326754A1 (en) * 2022-05-11 2025-10-23 adMare Therapeutics Society DNA-PK Inhibitor Compounds and Uses Thereof
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