KR20200100644A - 암을 사정하고 치료하기 위한 방법과 재료 - Google Patents
암을 사정하고 치료하기 위한 방법과 재료 Download PDFInfo
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Abstract
본 문서는 포유동물이 질환 (예를 들면, 암)을 겪는 것으로 확인하는데 이용될 수 있는 생물마커 (예를 들면, 펩티드 생물마커)를 확인하기 위한 방법과 재료를 제공한다. 본 문서는 또한, 암을 확인하고 및/또는 치료하기 위한 방법과 재료를 제공한다. 예를 들면, 본 문서는 포유동물이 암 (예를 들면, 난소암)을 겪는 것으로 확인하기 위해, 펩티딜-프로릴 시스-트랜스 이성화효소 A (PPIA) 폴리펩티드로부터 유래된 하나 또는 그 이상의 펩티드 단편을 이용하기 위한 방법과 재료를 제공한다.
Description
관련된 출원에 대한 교차 참조
본 출원은 2017년 11월 20일자 제출된 U.S. 특허 출원 일련 번호 62/588,654에 우선권을 주장한다. 상기 우선권 출원의 개시는 본 출원의 개시의 일부인 것으로 간주된다 (그리고 본 출원에 참조로서 편입된다).
배경
1. 기술 분야
본 문서는 포유동물이 질환 (예를 들면, 암)을 겪는 것으로 확인하는데 이용될 수 있는 생물마커 (예를 들면, 펩티드 생물마커)를 확인하기 위한 방법과 재료를 제공한다. 본 문서는 또한, 암을 확인하고 및/또는 치료하기 위한 방법과 재료를 제공한다. 예를 들면, 본 문서는 포유동물이 암 (예를 들면, 난소암)을 겪는 것으로 확인하기 위해, 펩티딜-프로릴 시스-트랜스 이성화효소 A (PPIA) 폴리펩티드로부터 유래된 하나 또는 그 이상의 펩티드 단편을 이용하기 위한 방법과 재료를 제공한다.
2. 배경 정보
백만 명 중 거의 4분의 1의 여성이 올해 난소암으로 진단될 것이고, 그리고 140,000명 이상의 여성이 상기 질환으로 사망할 것이다 (Howlader et al. 2014 SEER Cancer Statistics Review, 1975-2011 (National Cancer Institute, Bethesda)). 만약 난소암이 난소 외부로 확산하기 전, 초기 단계에서 진단되고 치료된다면, 5-년 상대 생존율은 90% 이상이다 (Howlader et al. 2014 SEER Cancer Statistics Review, 1975-2011 (National Cancer Institute, Bethesda)). 하지만, 모든 난소암 중에서 단지 15%만 이런 초기 단계에서 발견되고, 그리고 암이 후기 단계에서 발견되는 환자에 대한 예후는 암울하다 (Howlader et al. 2014 SEER Cancer Statistics Review, 1975-2011 (National Cancer Institute, Bethesda)). 따라서 난소암을 조기에 잠재적으로 검출할 수 있는 생물마커의 개발에 대한 필요성이 폭넓게 인식되고 있다. 이런 검출을 위해 전통적인 생물마커, 예컨대 CA-125 또는 HE-4를 이용하거나, 또는 초음파를 이용하려는 다양한 시도가 있었다 (Fishman et al. 2005 Am J Obstet Gynecol 192:1214-1221; Li et al. 2009 Expert Rev Mol Diagn 9:555-566; Scholler et al. 2007 Biomarkers Med 1:513-523; 및 Van Gorp et al. 2011 Br J Cancer 104:863-870). 비록 일부가 가능성을 보여주긴 하지만, 이들 중에서 어느 것도 미국 질병예방특별위원회에 의한 선별검사에 권장되지 않는데, 그 이유는 이들이 너무 빈번하게, "암을 겪지 않는 여성에서 주요 외과적 개입을 비롯한, 중요한 손상"을 야기하기 때문이다 (Moyer et al. 2012 Ann Intern Med 157:900-904).
요약
본 문서는 암을 확인하고 및/또는 치료하기 위한 방법과 재료를 제공한다. 일부 사례에서, 본 문서는 포유동물이 암 (예를 들면, 난소암)을 겪는 것으로 확인하기 위해, 하나 또는 그 이상의 PPIA 펩티드 단편을 이용하기 위한 재료와 방법을 제공한다. 예를 들면, 표본 (예를 들면, 비침습성 표본, 예컨대 혈액 표본) 내에 상승된 수준의 하나 또는 그 이상의 PPIA 펩티드 단편이 포유동물이 난소암을 겪는 것으로 확인하는데 이용될 수 있다. 예를 들면, 상승된 수준의 하나 또는 그 이상의 순환하는 펩티드 생물마커 (예를 들면, 하나 또는 그 이상의 PPIA 펩티드 단편)에 적어도 부분적으로 근거하여, 암 (예를 들면, 난소암)을 겪는 것으로 확인된 포유동물은 한 가지 또는 그 이상의 암 치료로 치료될 수 있다.
본 문서는 또한, 포유동물이 암을 겪는 것으로 확인하기 위한 생물마커로서 이용될 수 있는 펩티드 생물마커 (예를 들면, 순환하는 펩티드 생물마커)를 확인하고 및/또는 검증하기 위한 방법과 재료를 제공한다. 일부 사례에서, 복수의 순환하는 펩티드 생물마커가 정성적 및 정량적 질량 분광분석법 (MS) 기술의 조합을 이용하여 확인될 수 있다. 예를 들면, 암 환자 및 건강한 개체로부터 표본의 전역 혈장 프로테오믹 프로파일링이 후보 펩티드 생물마커를 확인하는데 이용될 수 있고, 그리고 각 후보 펩티드 생물마커는 이러한 후보 펩티드 마커(들)를 검증하기 위해, 분획된 용출물의 선별된 반응 모니터링 (SAFE-SRM)에 의한 순차적 분석에 의해 평가될 수 있다. 일부 사례에서, 본원에서 확인된 하나 또는 그 이상의 펩티드 (예를 들면, 하나 또는 그 이상의 순환하는 펩티드 생물마커)가 본원에서 설명된 바와 같이, 포유동물이 질환 (예를 들면, 암)을 겪는 것으로 확인하는데 이용될 수 있다.
본원에서 증명된 바와 같이, SAFE-SRM은 암에 대한 순환하는 (예를 들면, 혈액 내에) 펩티드 생물마커의 발견과 검증에 이용될 수 있다. 수백 개의 후보 펩티드 생물마커가 암 환자의 혈장으로부터 유래된 단백질분해 펩티드 및 건강한 개체로부터 유래된 단백질분해 펩티드의 비교를 통해 확인되었고, 그리고 SRM과 연계된 2D 크로마토그래피가 진단적으로 유용한 것으로 증명될지도 모르는 더욱 적은 숫자의 후보 펩티드 생물마커를 검증하는데 이용되었다. 본원에서 증명된 바와 같이, 이러한 접근법은 암 환자로부터 혈장에 적용되었고, 그리고 존재비가 난소암 환자의 혈장에서는 증가하지만 건강한 대조에서는 그렇지 않은, PPIA 유전자에 의해 인코딩된 2개의 펩티드가 발견되었다. 이러한 접근법은 일반적으로, 임의의 질환 및/또는 다양한 질환 상태에 특유한 단백질 및 펩티드 생물마커의 발견에 적용될 수 있다.
후보 펩티드 생물마커의 검증을 포함하는 고처리량의 견실하고 재현 가능한 시스템에서 펩티드 생물마커를 확인하는 능력을 갖는 것은 다수의 후보 펩티드 생물마커를 정량적인 대량 병렬 방식으로 확인하고 검증하기 위한 독특하고 실현되지 않은 기회를 제공한다. 이에 더하여, 혈액 표본 내에 순환하는 펩티드 생물마커를 검출하는 능력을 갖는 것은 전통적인 방법을 이용하여 및/또는 비침습성 표본 방식을 이용하여 달성될 수 있는 것보다 앞선 단계에서, 포유동물이 암을 겪는 것으로 확인하기 위한 독특하고 실현되지 않은 기회를 제공한다.
일반적으로, 본 문서의 한 가지 양상은 난소암을 치료하기 위한 방법을 특징으로 한다. 상기 방법은 포유동물로부터 획득된 혈액 표본 내에 PPIA 폴리펩티드로부터 유래된 펩티드 단편을 포함하는 상승된 수준의 하나 또는 그 이상의 펩티드 생물마커를 검출하는 단계, 그리고 한 가지 또는 그 이상의 암 치료를 상기 포유동물에게 투여하는 단계를 포함하거나, 또는 이들 단계로 본질적으로 구성된다. 한 가지 또는 그 이상의 암 치료는 수술, 화학요법, 호르몬 요법, 표적화된 요법, 방사선요법, 또는 이들의 임의의 조합을 포함할 수 있다. 포유동물은 인간일 수 있다. 혈액 표본은 혈장 표본일 수 있다. PPIA 펩티드 단편은 아미노산 서열 VSFELFADK (서열 번호: 1)를 포함할 수 있다. PPIA 펩티드 단편은 아미노산 서열 FEDENFILK (서열 번호: 2)를 포함할 수 있다.
다른 양상에서, 본 문서는 포유동물이 난소암을 겪는 것으로 확인하기 위한 방법을 특징으로 한다. 상기 방법은 상기 포유동물로부터 획득된 혈액 표본 내에 PPIA 폴리펩티드로부터 유래된 펩티드 단편을 포함하는 하나 또는 그 이상의 혈액 펩티드 생물마커의 수준을 검출하는 단계, 그리고 상승된 수준의 하나 또는 그 이상의 혈액 펩티드 생물마커가 상기 혈액 표본에서 검출될 때, 상기 포유동물이 난소암을 겪는 것으로 진단하는 단계를 포함하거나, 또는 이들 단계로 본질적으로 구성된다. 포유동물은 인간일 수 있다. 혈액 표본은 혈장 표본일 수 있다. PPIA 펩티드 단편은 아미노산 서열 VSFELFADK (서열 번호: 1)를 포함할 수 있다. PPIA 펩티드 단편은 아미노산 서열 FEDENFILK (서열 번호: 2)를 포함할 수 있다.
다른 양상에서, 본 문서는 펩티드 생물마커를 확인하기 위한 방법을 특징으로 한다. 상기 방법은 질환 혈액 표본 내에 존재하는 폴리펩티드를 소화시켜 질환 펩티드 단편을 획득하고 이들 질환 펩티드 단편을 첫 번째 중동위원소로 표지화하여 표지화된 질환 펩티드 단편을 획득하는 단계; 참조 혈액 표본 내에 존재하는 폴리펩티드를 소화시켜 참조 펩티드 단편을 획득하고 이들 참조 펩티드 단편을 두 번째 중동위원소로 표지화하여 표지화된 참조 펩티드 단편을 획득하는 단계; 그리고 표지화된 질환 펩티드 단편 및 표지화된 참조 펩티드 단편을 질량 분광분석법에 종속시켜 펩티드 생물마커를 확인하는 단계를 포함하거나, 또는 이들 단계로 본질적으로 구성되고, 여기서 펩티드 생물마커의 수준은 표지화된 참조 펩티드 단편에 비하여 표지화된 질환 펩티드 단편에서 상승된다. 질환 혈액 표본은 질환을 겪는 한 마리 또는 그 이상의 포유동물로부터 획득된 혈액을 포함할 수 있다. 질환 혈액 표본은 질환을 겪는 복수의 포유동물로부터 획득된 혈액을 포함할 수 있다. 참조 혈액 표본은 한 마리 또는 그 이상의 건강한 포유동물로부터 획득된 혈액을 포함할 수 있다. 참조 혈액 표본은 복수의 건강한 포유동물로부터 획득된 혈액을 포함할 수 있다. 상기 방법은 또한, 각 표본으로부터 한 가지 또는 그 이상의 매우 풍부한 혈액 단백질을 고갈시키는 단계를 포함할 수 있다. 매우 풍부한 혈액 단백질은 알부민, IgG, α1-항트립신, IgA, IgM, 트랜스페린, 합토글로빈, α2-마크로글로불린, 피브리노겐, 보체 C3, α1-산 당단백질, 아포지질단백질 A-I, 아포지질단백질 A-II, 아포지질단백질 B, 또는 이들의 임의의 조합일 수 있다. 상기 방법은 또한, 각 소화 단계에 앞서, 각 표본에서 당단백질을 농축하는 단계를 포함할 수 있다. 질량 분광분석법은 Orbitrap 질량분광계를 이용하여 수행될 수 있다.
다른 양상에서, 본 문서는 펩티드 생물마커를 검증하기 위한 방법을 특징으로 한다. 상기 방법은 펩티드 생물마커를 포함하는 복수의 펩티드를 염기성 pH 역상 액체 크로마토그래피 (bRPLC)에 종속시켜 복수의 분획물을 획득하는 단계; 복수의 분획물을 복수의 분획물 군으로 조직화하되, 분획물의 숫자가 분획물 군의 숫자보다 많은 단계; 각 분획물 군에서 펩티드 생물마커를 산성 pH에서 직교 고성능 액체 크로마토그래피 (HPLC)에 의해 분리하여 연속 HPLC 용리액을 획득하는 단계; 그리고 펩티드 생물마커에 대한 미리 최적화된 트랜지션 및 미리 최적화된 체류 시간을 포함하는 선별된 반응 모니터링 (SRM) 방법을 이용하여 상기 연속 HPLC 용리액을 분석하여, 상기 펩티드 생물마커의 강도를 결정하는 단계를 포함하거나, 또는 이들 단계로 본질적으로 구성되고; 여기서 펩티드 생물마커는 이러한 펩티드 생물마커가 SRM 방법을 이용하여, 참조 표본에 비하여 질환 표본에서 상승된 수준에서 검출되고 정량될 때 검증된다. 펩티드 생물마커에 대한 이러한 방법 최적화된 체류 시간은 이러한 펩티드 생물마커의 강도에 역비례할 수 있다. HPLC는 질량분광계에 연계되는 장치로 수행될 수 있다. 질량분광계는 삼중 4극 질량분광계일 수 있다. 충돌 에너지는 데이터세트 S5에서 진술된 충돌 에너지 중에서 한 가지일 수 있다. 체류 시간은 데이터세트 S5에서 진술된 체류 시간 중에서 한 가지일 수 있다.
다른 양상에서, 본 문서는 펩티드 생물마커를 확인하고 검증하기 위한 방법을 특징으로 한다. 상기 방법은 후보 펩티드 생물마커를 확인하는 단계, 후보 펩티드 생물마커에 대한 SAFE-SRM 방법을 구축하는 단계, 그리고 SAFE-SRM 방법을 이용하여 후보 펩티드 생물마커를 검증하는 단계를 포함하거나, 또는 이들 단계로 본질적으로 구성된다.
후보 펩티드 생물마커를 확인하는 것은 질환 혈액 표본 내에 존재하는 폴리펩티드를 소화시켜 질환 펩티드 단편을 획득하는 단계, 질환 펩티드 단편을 첫 번째 중동위원소로 표지화하여 표지화된 질환 펩티드 단편을 획득하는 단계, 참조 혈액 표본 내에 존재하는 폴리펩티드를 소화시켜 참조 펩티드 단편을 획득하는 단계, 참조 펩티드 단편을 두 번째 중동위원소로 표지화하여 표지화된 참조 펩티드 단편을 획득하는 단계, 그리고 표지화된 질환 펩티드 단편 및 표지화된 참조 펩티드 단편을 질량 분광분석법에 종속시켜 후보 펩티드 생물마커를 확인하는 단계를 포함하거나, 또는 이들 단계로 본질적으로 구성될 수 있고, 여기서 후보 펩티드 생물마커의 수준은 표지화된 참조 펩티드 단편에 비하여 표지화된 질환 펩티드 단편에서 상승된다. SAFE-SRM 방법을 구축하는 것은 후보 펩티드 생물마커를 합성하는 단계, 합성 후보 펩티드 생물마커를 질량 분광분석법에 종속시켜 후보 펩티드 생물마커 트랜지션을 결정하되, 상기 트랜지션이 가장 강한 강도를 갖는 선구 이온-생성 이온 쌍을 확인하고 이러한 선구 이온-생성 이온 쌍을 생산하는 충돌 에너지 (CE)를 확인함으로써 결정되는 단계, 후보 펩티드 생물마커를 포함하는 복수의 펩티드를 bRPLC에 종속시켜 복수의 분획물을 획득하되, 상기 복수의 분획물이 본질적으로 동등한 양의 각 펩티드로 구성되는 단계, 복수의 분획물을 복수의 분획물 군으로 조직화하되, 분획물의 숫자가 분획물 군의 숫자보다 많은 단계, 후보 펩티드 생물마커 트랜지션 및 고정된 체류 시간을 이용하여, 분획물 군 각각에서 상기 후보 펩티드 생물마커의 강도를 결정하는 단계, 그리고 이들 트랜지션을 높은 pH에서 그들의 소수성에 따라서 재조립함으로써 체류 시간을 최적화하는 단계를 포함하거나, 또는 이들 단계로 본질적으로 구성될 수 있다. 상기 후보 펩티드 생물마커를 검증하는 것은 질환 혈액 표본에서 후보 펩티드 생물마커를 정량하고, 상기 후보 펩티드 생물마커를 포함하는 상기 질환 펩티드 단편을 bRPLC에 종속시킴으로써 복수의 분획물을 획득하고, 상기 복수의 분획물을 복수의 분획물 군으로 조직화하고, 여기서 분획물의 숫자가 분획물 군의 숫자보다 많고, 각 분획물 군에서 펩티드를 산성 pH에서 직교 HPLC에 의해 분리하여 연속 HPLC 용리액을 획득하고, 그리고 후보 펩티드 생물마커 트랜지션 및 최적화된 체류 시간을 포함하는 SRM 방법을 이용하여 상기 연속 HPLC 용리액을 분석하는 단계; 그리고 참조 혈액 표본에서 후보 펩티드 마커를 정량하고, 참조 펩티드 단편을 bRPLC에 종속시킴으로써 복수의 분획물을 획득하고, 복수의 분획물을 복수의 분획물 군으로 조직화하고, 여기서 분획물의 숫자가 분획물 군의 숫자보다 많고, 각 분획물 군에서 펩티드를 산성 pH에서 직교 HPLC에 의해 분리하여 연속 HPLC 용리액을 획득하고, 그리고 후보 펩티드 생물마커 트랜지션 및 최적화된 체류 시간을 포함하는 SRM 방법을 이용하여 상기 연속 HPLC 용리액을 분석하는 단계; 그리고 후보 펩티드 생물마커가 참조 표본에 비하여 질환 표본에서 상승된 수준에서 정량될 때, 상기 후보 펩티드 생물마커를 검증하는 단계를 포함하거나, 또는 이들 단계로 본질적으로 구성될 수 있다. 합성된 후보 펩티드 생물마커는 중동위원소로 표지화될 수 없다. 펩티드 생물마커에 대한 최적화된 체류 시간은 개체로부터 획득된 표본 내에 존재하는 스파이킹된 합성 생물마커 펩티드를 이용하여 결정된다. 펩티드 생물마커에 대한 이러한 방법 최적화된 체류 시간은 이러한 펩티드 생물마커의 강도에 역비례할 수 있다. HPLC는 질량분광계에 연계되는 장치로 수행될 수 있다. 질량분광계는 삼중 4극 질량분광계일 수 있다. 충돌 에너지는 데이터세트 S5에서 진술된 충돌 에너지 중에서 한 가지일 수 있다. 체류 시간은 데이터세트 S5에서 진술된 체류 시간 중에서 한 가지일 수 있다.
별도로 규정되지 않으면, 본원에서 이용된 모든 기술 용어와 과학 용어는 본 발명이 속하는 당해 분야의 평균적 기술자에 의해 통상적으로 이해되는 바와 동일한 의미를 갖는다. 비록 본원에서 설명된 것들과 유사하거나 균등한 방법과 재료가 본 발명을 실시하는데 이용될 수 있지만, 적절한 방법과 재료가 하기에 설명된다. 본원에서 언급된 모든 간행물, 특허 출원, 특허 및 기타 참고문헌은 전체적으로 참조로서 편입된다. 충돌의 경우에, 정의를 비롯한 본 명세서가 우선할 것이다. 이에 더하여, 이들 재료, 방법 및 실례는 단지 예시이고 제한하는 것으로 의도되지 않는다.
본 발명의 하나 또는 그 이상의 구체예에 관한 상세가 첨부한 도면 및 이하의 설명에서 제시된다. 본 발명의 다른 특징, 목적과 이점은 상세한 설명과 도면으로부터, 그리고 청구항으로부터 명백할 것이다.
도면에 관한 설명
도 1은 혈장 생물마커 확인과 검증의 작업 흐름의 계통도를 내포한다. 혈장 생물마커 발견과 확인은 표지화-의존성 정량적 단백질체학, 예컨대 iTRAQ 또는 TMT 검정 (A)을 통해 수행되었고; 혈장 생물마커 검증은 SAFE-SRM (B)을 통해 수행되었다.
도 2는 복합 표본에서 SAFE-SRM에 의한 펩티드 검출감도를 도시한다. 6개의 중동위원소-표지화된 펩티드 (펩티드 1: IQLVEEELDR* (서열 번호:3); 펩티드 2: VILHLK* (서열 번호:4); 펩티드 3: IILLFDAHK* (서열 번호:5); 펩티드 4: TLAESALQLLYTAK* (서열 번호:6); 펩티드 5: LLGHLVK* (서열 번호:7); 펩티드 6: GLVGEIIK* (서열 번호:8), 여기서 *는 C13과 N15 중동위원소-표지화된 아미노산을 지시한다)가 합성되고, 그리고 복합 표본 내에 적은 양의 펩티드를 검출할 때 SAFESRM의 민감도를 평가하는데 이용되었다. 1 펨토몰의 각 펩티드는 전통적인 SRM에 의해 검출되었다 (A). 하지만, 1 fmol의 이들 펩티드가 트립신-소화된 혈장 표본에 첨가될 때, 이들은 검출하기가 훨씬 어려웠다 (B). bRPLC 분별이 표준 SRM의 민감도를 증가시킬 수 있긴 하지만, 실행 사이에 변동이 컸다 (C). 최적화된 체류 시간과 순환 시간을 갖는 SAFE-SRM은 평균적으로, 자유 펩티드의 강도의 70% 강도에서 6개 펩티드 모두의 검출을 가능하게 하였다 (D).
도 3은 펩티드 생물마커에 의한 난소암 예측을 도시한다. (A) 318개 펩티드 모두의 난소암 예측의 평균 자승 오차 (MSEs)가 MSE에 의해 최고 예측자로부터 최악 예측자까지 순위 매겨진 펩티드로 플롯팅된다. (B) 10개의 최고 펩티드 생물마커가 도시된다; 펩티딜-프로릴 시스-트랜스 이성화효소 A로부터 펩티드 VSFELFADK가 최고 예측자이었다. (C) PPIA 펩티드 VSFELFADK의 난소암 예측 성과는 동일한 단백질로부터 다른 펩티드, FEDENFILK (서열 번호:2)와 조합함으로써 더욱 향상되었다.
도 4는 총 혈장 단백질체 (A) 및 혈장 당단백질체 (B)를 이용한 iTRAQ-표지화-기초된 정량적 단백질체학 연구에 대한 상세한 기술적인 작업 흐름을 내포한다.
도 5는 SAFE-SRM 계획을 내포한다. (A) 복잡해진 생물학적 표본으로부터 펩티드를 높은 pH에서 그들의 소수성에 따라서 96개의 분획물로 분리하기 위해 bRPLC 분별이 수행되었다. 이들 SAFE-SRM 분획물 군은 웰 상에 덧씌워진다. (B) 최종 SAFE-SRM 방법에서 이용되는 20개의 SAFE-SRM 분획물 군 각각에서 모든 펩티드의 통합 신호 강도를 보여주는 크로마토그램. (C) SAFE-SRM 방법 트랜지션 적용범위. 각 분획물 군 i에 대해, 특정한 SAFE-SRM 방법 i는 상기 분획물 군 및 2개의 인접한 군, 군 i - 1 및 군 i + 1 (여기서 i ∈) 내에 펩티드를 검출하는 트랜지션으로 구성된다.
도 6은 8개의 혈장 표본에서 3개의 난소암 생물마커 펩티드에 대한 SAFE-SRM 프로필을 내포한다. 4개의 난소암 혈장 표본 (253, 256, 260 및 271) 및 4개의 정상적인 건강한 혈장 표본 (202, 205, 207 및 209)이 SAFE-SRM에 의해 분석되었다. 각 표본에 대한 피크 아래 면적이 도시된다.
도 7은 SAFE-SRM-기초된 PPIA 검정 및 ELISA-기초된 CA125 검정을 이용한, 난소암 진단 성과의 비교를 내포한다. 벤 다이어그램은 63명 난소암 환자의 코호트에서 확인된 사례의 숫자를 보여준다.
도 8은 PPIA로부터 SAFE-SRM 표적 펩티드의 MS 스펙트럼을 내포한다.
도 9는 전체-혈장 iTRAQ 데이터세트에 대한 MA 플롯을 내포한다. 3번의 실험 각각으로부터 비정규화된 펩티드 강도가 각 특정한 표지화 (114, 115, 116 및 117) 하에 비교되었고, 그리고 상응하는 MA 플롯이 로그 변환된 원시 강도를 이용하여 산출되었는데, A 범위는 6-14에 고정되고, 그리고 M 범위는 -4 내지 4에 고정되었다. 이들 데이터세트 중에서 어느 것과 연관된 편향의 명백한 증거는 없다. 기술적 분산 (I-L)은 생물학적 분산 (A-D 또는 E-H)보다 훨씬 작다.
도 10은 3개의 데이터세트에서 암 대 정상에 대한 비정규화된 및 중앙값 정규화된 히스토그램을 도시한다. 암/정상의 단백질 비율이 데이터세트 1 (A-C, 위쪽), 데이터세트 2 (A-C, 중간), 그리고 데이터세트 3 (A-C, 아래쪽)에 대해 log2 규모를 이용하여 플롯팅되었다. 중앙값 정규화 후, 암/정상의 동일한 단백질 비율이 데이터세트 1 (D-F, 위쪽), 데이터세트 2 (D-F, 중간), 그리고 데이터세트 3 (D-F, 아래쪽)에 대해 log2 규모를 이용하여 플롯팅되었다. log2 (상대적 비율) = 0 라인은 각 플롯에서 표시된다 (적색선). 결장직장암 (B) 및 난소암 (C)의 경우에 편향된 데이터가 관찰되었다. 췌장암 (A)에 대한 편향은 명확하지 않다.
도 1은 혈장 생물마커 확인과 검증의 작업 흐름의 계통도를 내포한다. 혈장 생물마커 발견과 확인은 표지화-의존성 정량적 단백질체학, 예컨대 iTRAQ 또는 TMT 검정 (A)을 통해 수행되었고; 혈장 생물마커 검증은 SAFE-SRM (B)을 통해 수행되었다.
도 2는 복합 표본에서 SAFE-SRM에 의한 펩티드 검출감도를 도시한다. 6개의 중동위원소-표지화된 펩티드 (펩티드 1: IQLVEEELDR* (서열 번호:3); 펩티드 2: VILHLK* (서열 번호:4); 펩티드 3: IILLFDAHK* (서열 번호:5); 펩티드 4: TLAESALQLLYTAK* (서열 번호:6); 펩티드 5: LLGHLVK* (서열 번호:7); 펩티드 6: GLVGEIIK* (서열 번호:8), 여기서 *는 C13과 N15 중동위원소-표지화된 아미노산을 지시한다)가 합성되고, 그리고 복합 표본 내에 적은 양의 펩티드를 검출할 때 SAFESRM의 민감도를 평가하는데 이용되었다. 1 펨토몰의 각 펩티드는 전통적인 SRM에 의해 검출되었다 (A). 하지만, 1 fmol의 이들 펩티드가 트립신-소화된 혈장 표본에 첨가될 때, 이들은 검출하기가 훨씬 어려웠다 (B). bRPLC 분별이 표준 SRM의 민감도를 증가시킬 수 있긴 하지만, 실행 사이에 변동이 컸다 (C). 최적화된 체류 시간과 순환 시간을 갖는 SAFE-SRM은 평균적으로, 자유 펩티드의 강도의 70% 강도에서 6개 펩티드 모두의 검출을 가능하게 하였다 (D).
도 3은 펩티드 생물마커에 의한 난소암 예측을 도시한다. (A) 318개 펩티드 모두의 난소암 예측의 평균 자승 오차 (MSEs)가 MSE에 의해 최고 예측자로부터 최악 예측자까지 순위 매겨진 펩티드로 플롯팅된다. (B) 10개의 최고 펩티드 생물마커가 도시된다; 펩티딜-프로릴 시스-트랜스 이성화효소 A로부터 펩티드 VSFELFADK가 최고 예측자이었다. (C) PPIA 펩티드 VSFELFADK의 난소암 예측 성과는 동일한 단백질로부터 다른 펩티드, FEDENFILK (서열 번호:2)와 조합함으로써 더욱 향상되었다.
도 4는 총 혈장 단백질체 (A) 및 혈장 당단백질체 (B)를 이용한 iTRAQ-표지화-기초된 정량적 단백질체학 연구에 대한 상세한 기술적인 작업 흐름을 내포한다.
도 5는 SAFE-SRM 계획을 내포한다. (A) 복잡해진 생물학적 표본으로부터 펩티드를 높은 pH에서 그들의 소수성에 따라서 96개의 분획물로 분리하기 위해 bRPLC 분별이 수행되었다. 이들 SAFE-SRM 분획물 군은 웰 상에 덧씌워진다. (B) 최종 SAFE-SRM 방법에서 이용되는 20개의 SAFE-SRM 분획물 군 각각에서 모든 펩티드의 통합 신호 강도를 보여주는 크로마토그램. (C) SAFE-SRM 방법 트랜지션 적용범위. 각 분획물 군 i에 대해, 특정한 SAFE-SRM 방법 i는 상기 분획물 군 및 2개의 인접한 군, 군 i - 1 및 군 i + 1 (여기서 i ∈) 내에 펩티드를 검출하는 트랜지션으로 구성된다.
도 6은 8개의 혈장 표본에서 3개의 난소암 생물마커 펩티드에 대한 SAFE-SRM 프로필을 내포한다. 4개의 난소암 혈장 표본 (253, 256, 260 및 271) 및 4개의 정상적인 건강한 혈장 표본 (202, 205, 207 및 209)이 SAFE-SRM에 의해 분석되었다. 각 표본에 대한 피크 아래 면적이 도시된다.
도 7은 SAFE-SRM-기초된 PPIA 검정 및 ELISA-기초된 CA125 검정을 이용한, 난소암 진단 성과의 비교를 내포한다. 벤 다이어그램은 63명 난소암 환자의 코호트에서 확인된 사례의 숫자를 보여준다.
도 8은 PPIA로부터 SAFE-SRM 표적 펩티드의 MS 스펙트럼을 내포한다.
도 9는 전체-혈장 iTRAQ 데이터세트에 대한 MA 플롯을 내포한다. 3번의 실험 각각으로부터 비정규화된 펩티드 강도가 각 특정한 표지화 (114, 115, 116 및 117) 하에 비교되었고, 그리고 상응하는 MA 플롯이 로그 변환된 원시 강도를 이용하여 산출되었는데, A 범위는 6-14에 고정되고, 그리고 M 범위는 -4 내지 4에 고정되었다. 이들 데이터세트 중에서 어느 것과 연관된 편향의 명백한 증거는 없다. 기술적 분산 (I-L)은 생물학적 분산 (A-D 또는 E-H)보다 훨씬 작다.
도 10은 3개의 데이터세트에서 암 대 정상에 대한 비정규화된 및 중앙값 정규화된 히스토그램을 도시한다. 암/정상의 단백질 비율이 데이터세트 1 (A-C, 위쪽), 데이터세트 2 (A-C, 중간), 그리고 데이터세트 3 (A-C, 아래쪽)에 대해 log2 규모를 이용하여 플롯팅되었다. 중앙값 정규화 후, 암/정상의 동일한 단백질 비율이 데이터세트 1 (D-F, 위쪽), 데이터세트 2 (D-F, 중간), 그리고 데이터세트 3 (D-F, 아래쪽)에 대해 log2 규모를 이용하여 플롯팅되었다. log2 (상대적 비율) = 0 라인은 각 플롯에서 표시된다 (적색선). 결장직장암 (B) 및 난소암 (C)의 경우에 편향된 데이터가 관찰되었다. 췌장암 (A)에 대한 편향은 명확하지 않다.
상세한 설명
본 문서는 질환을 확인하고 및/또는 치료하기 위한 방법과 재료를 제공한다. 일부 사례에서, 질환은 암이다. 예를 들면, 상승된 수준의 하나 또는 그 이상의 순환하는 펩티드 생물마커 (예를 들면, PPIA 펩티드 단편)을 갖는 포유동물은 암 (예를 들면, 난소암)을 겪는 것으로 확인될 수 있고, 그리고 임의적으로, 한 가지 또는 그 이상의 암 치료가 투여될 수 있다. 본원에서 이용된 바와 같이, "순환하는 펩티드"는 포유동물의 신체 내에서 임의의 폐쇄 시스템 (예를 들면, 순환계)에서 검출될 수 있는 펩티드이다. 일부 사례에서, 포유동물 (예를 들면, 암을 겪는 것으로 의심되는 포유동물)로부터 혈액 표본 (예를 들면, 혈장 표본)이 상승된 수준의 하나 또는 그 이상의 PPIA 펩티드 단편에 대해 사정될 수 있고, 그리고 상승된 수준의 하나 또는 그 이상의 PPIA 펩티드 단편이 검출될 때, 상기 포유동물은 암을 겪는 것으로 확인될 수 있고, 그리고 임의적으로, 상기 포유동물은 암의 심각도를 감소시키고 및/또는 암의 증상을 감소시키기 위한 한 가지 또는 그 이상의 암 치료가 투여될 수 있다.
본원에서 이용된 바와 같이, 순환하는 펩티드 생물마커 (예를 들면, PPIA 펩티드 단편)의 수준에 대하여 용어 "상승된 수준"은 한 마리 또는 그 이상의 건강한 포유동물 (예를 들면, 암을 겪지 않는 포유동물)로부터 표본 (예를 들면, 참조 표본)에서 전형적으로 관찰되는 순환하는 펩티드 (예를 들면, PPIA 펩티드 단편)의 참조 수준보다 큰 임의의 수준을 지칭한다. 일부 사례에서, 참조 표본은 상승된 수준의 순환하는 펩티드와 연관되는 질환을 전시하지 않는 포유동물로부터 획득된 표본일 수 있다. 예를 들면, 난소암과 연관된 펩티드 생물마커의 경우에, 참조 표본은 난소암을 겪지 않는 개체로부터 획득된 표본일 수 있다. 일부 사례에서, 참조 표본은 상승된 수준의 펩티드 생물마커가 관찰되는 동일한 포유동물로부터 획득된 표본일 수 있는데, 여기서 상기 참조 표본은 상승된 수준의 순환하는 펩티드와 연관되는 질환의 개시에 앞서 획득되었다. 일부 사례에서, 동일한 포유동물로부터 획득된 이런 참조 표본은 참조 표본으로서 장래 이용을 위해 동결되거나 또는 만약 그렇지 않으면 보존된다. 일부 사례에서, 상승된 수준의 하나 또는 그 이상의 PPIA 단편은 본원에서 설명된 바와 같이 존재비 점수 역치에 근거하여 사정될 수 있다 (참조: 예를 들면, 실시예 1 및 데이터세트 S7). 일부 사례에서, 참조 표본이 검출할 수 없는 수준의 순환하는 펩티드 생물마커를 가질 때, 상승된 수준은 순환하는 펩티드 생물마커의 임의의 검출가능한 수준일 수 있다. 특정 수준이 상승된 수준 인지의 여부를 결정할 때, 필적하는 표본으로부터 수준이 이용되는 것으로 인지될 것이다.
임의의 적합한 포유동물이 본원에서 설명된 바와 같이 사정되고 및/또는 치료될 수 있다. 예를 들면, 인간 또는 다른 영장류, 예컨대 원숭이가 상승된 수준의 하나 또는 그 이상의 PPIA 펩티드 단편에 대해 사정될 수 있고, 그리고 임의적으로, 인간 또는 다른 영장류 내에 존재하는 암 세포의 숫자를 감소시키기 위한 한 가지 또는 그 이상의 암 치료로 치료될 수 있다. 일부 사례에서, 암을 겪는 개, 고양이, 말, 소, 돼지, 양, 생쥐 및 쥐가 상승된 수준의 하나 또는 그 이상의 PPIA 펩티드 단편에 대해 사정될 수 있고, 그리고 임의적으로, 본원에서 설명된 바와 같이 인간 또는 다른 영장류 내에 존재하는 암 세포의 숫자를 감소시키기 위한 한 가지 또는 그 이상의 암 치료로 치료될 수 있다.
포유동물로부터 획득된 임의의 적합한 표본이 본원에서 설명된 바와 같이 사정될 수 있다 (예를 들면, 상승된 수준의 하나 또는 그 이상의 순환하는 펩티드 생물마커에 대해 사정될 수 있다). 순환하는 펩티드 생물마커를 내포할 수 있는 표본의 실례는 제한 없이, 혈액 표본 (예를 들면, 전혈, 혈청, 또는 혈장 표본), 혈액, 혈장, 소변, 뇌척수액, 타액, 객담, 기관지폐포 세척액, 담즙, 림프액, 낭액, 대변, 그리고 복수를 포함한다. 일부 사례에서, 표본은 혈장 표본일 수 있다.
하나 또는 그 이상의 순환하는 펩티드 생물마커는 임의의 적합한 순환하는 펩티드 생물마커일 수 있다. 일부 사례에서, 순환하는 펩티드 생물마커는 본원에서 설명된 임의의 방법을 이용하여 확인되고 검증된다 (예를 들면, SAFE-ARM 방법을 이용). 하나 또는 그 이상의 PPIA 펩티드 단편은 임의의 적합한 PPIA 펩티드 단편을 포함할 수 있다. PPIA 펩티드 단편의 실례는 제한 없이, 아미노산 서열 VSFELFADK (서열 번호: 1)를 포함하는 펩티드 단편 및 아미노산 서열 FEDENFILK (서열 번호: 2)를 포함하는 펩티드 단편을 포함한다.
임의의 적합한 방법이 상승된 수준의 하나 또는 그 이상의 순환하는 펩티드 생물마커를 검출하는데 이용될 수 있다. 펩티드 수준을 검출하기 위한 방법의 실례는 제한 없이, 분광분석 방법 (예를 들면, 고성능 액체 크로마토그래피 (HPLC) 및 액체 크로마토그래피-질량 분광분석법 (LC/MS)), 항체 의존성 방법 (예를 들면, 효소 결합 면역흡착 검정 (ELISA), 단백질 면역침전, 면역전기이동, 웨스턴 블롯팅 및 단백질 면역염색), 그리고 앱타머 의존성 방법을 포함한다. 일부 사례에서, 하나 또는 그 이상의 순환하는 펩티드 생물마커 (예를 들면, 하나 또는 그 이상의 PPIA 펩티드 단편)은 질량 분광분석법 기술을 이용하여 검출될 수 있다.
일부 사례에서, 본원에서 설명된 바와 같이 암을 겪는 것으로 확인된 (예를 들면, 상승된 수준의 하나 또는 그 이상의 순환하는 펩티드 생물마커에 적어도 부분적으로 근거하여) 포유동물은 임의의 적합한 방법을 이용하여 암 진단이 확증될 수 있다. 암을 진단하는데 이용될 수 있는 방법의 실례는 제한 없이, 신체 검사 (예를 들면, 골반 검사), 영상 검사 (예를 들면, 초음파 또는 CT 스캔), 혈액 검사 (예를 들면, 마커, 예컨대 CA 125에 대한), 조직 검사 (예를 들면, 생검)를 포함한다.
일단 본원에서 설명된 바와 같이 암을 겪는 것으로 확인되면 (예를 들면, 상승된 수준의 하나 또는 그 이상의 순환하는 펩티드 생물마커, 예컨대 PPIA 펩티드 단편에 적어도 부분적으로 근거하여), 포유동물은 한 가지 또는 그 이상의 암 치료로 치료될 수 있다. 한 가지 또는 그 이상의 암 치료는 임의의 적합한 암 치료를 포함할 수 있다. 암 치료는 수술을 포함할 수 있다. 암이 난소암인 경우에, 수술은 어느 한쪽 또는 양쪽 난소, 난관, 자궁, 인근 림프절 및/또는 인근 지방 복부 조직 (장막)의 제거를 포함할 수 있다. 암 치료는 방사선요법을 포함할 수 있다. 암 치료는 약물요법, 예를 들면, 화학요법, 호르몬 요법, 표적화된 요법 및/또는 세포독성 요법을 투여하는 것을 포함할 수 있다. 암 치료의 실례는 제한 없이, 백금 화합물 (예컨대, 시스플라틴 또는 카르보플라틴), 탁산 (예컨대, 파클리탁셀 또는 도세탁셀), 알부민 결합된 파클리탁셀 (냅-파클리탁셀), 알트레타민, 카페시타빈, 시클로포스파미드, 에토포시드 (vp-16), 젬시타빈, 이포스파미드, 이리노테칸 (cpt-11), 리포솜 독소루비신, 멜팔란, 페메트렉시드, 토포테칸, 비노렐빈, 황체형성-호르몬-방출 호르몬 (LHRH) 효현제 (예컨대, 고세렐린 및 류프롤라이드), 항에스트로겐 요법 (예컨대, 타목시펜), 아로마타아제 저해제 (예컨대, 레트로졸, 아나스트로졸 및 엑세메스테인), 혈관형성 저해제 (예컨대, 베바시주맙), 폴리(ADP)-리보오스 중합효소 (PARP) 저해제 (예컨대, 올라파립, 루카파립 및 니라파립), 외부 빔 방사선요법, 근접치료, 방사성 인, 그리고 이들의 임의의 조합을 포함한다.
임의의 적합한 암이 본원에서 설명된 바와 같이 확인되고 및/또는 치료될 수 있다. 본원에서 설명된 바와 같이 치료될 수 있는 암의 실례는 제한 없이, 폐암 (예를 들면, 소세포 폐 암종 또는 비소세포 폐 암종), 유두상 갑상선암, 갑상선 수질암, 분화된 갑상선암, 재발성 갑상선암, 난치성 분화된 갑상선암, 폐 선암종, 세기관지 폐 세포 암종, 다발성 내분비성 종양형성 유형 2A 또는 2B (각각, MEN2A 또는 MEN2B), 크롬 친화성 세포종, 부갑상선 과형성, 유방암, 결장직장암 (예를 들면, 전이성 결장직장암), 유두상 신장 세포 암종, 위소장 점막층의 신경절신경종증, 염증성 근섬유모세포 종양, 또는 자궁경부암, 급성 림프모구성 백혈병 (ALL), 급성 골수성 백혈병 (AML), 청소년기의 암, 부신암, 부신 피질 암종, 항문암, 충수암, 성상세포종, 비정형 기형/횡문근양 종양, 기저 세포 암종, 담관암, 방광암, 골암, 뇌간 신경교종, 뇌 종양, 유방암, 기관지 종양, 버킷 림프종, 카르시노이드 종양, 원발 병소 불명 암종, 심장 종양, 자궁경부암, 소아암, 척삭종, 만성 림프성 백혈병 (CLL), 만성 골수성 백혈병 (CML), 만성 골수증식성 신생물, 결장암, 결장직장암, 두개인두종, 피부 T-세포 림프종, 담관암, 관상피내암, 태아 종양, 자궁내막암, 상의세포종, 식도암, 감각신경모세포종, 유잉 육종, 두개외 생식 세포 종양, 고환외 생식 세포 종양, 간외 담관암, 눈암, 난관암, 뼈의 섬유조직구종, 담낭암, 위암, 위장관 카르시노이드 종양, 위장관 간질 종양 (GIST), 생식 세포 종양, 임신성 영양막병, 신경교종, 모발상 세포 종양, 모양 세포성 백혈병, 두경부암, 심장암, 간세포암, 조직구증, 호지킨 림프종, 하인두암, 안구내 흑색종, 도세포 종양, 췌장 신경내분비 종양, 카포시 육종, 신장암, 랑게르한스 세포 조직구증, 후두암, 백혈병, 순암과 구강암, 간암, 폐암, 림프종, 마크로글로불린혈증, 뼈의 악성 섬유성 조직구종, 골암, 흑색종, 메르켈 세포 암종, 중피종, 전이성 편평상피 경부암, 중심선 관 암종, 구강암, 다발성 내분비성 종양형성 증후군, 다발성 골수종, 균상식육종, 골수형성이상 증후군, 골수형성이상/골수증식성 신생물, 골수성 백혈병, 골수성 백혈병, 다발성 골수종, 골수증식성 신생물, 비강암과 부비동암, 비인두암, 신경모세포종, 비호지킨 림프종, 비소세포 폐암, 구강암, 구강암, 구순암, 구인두암, 골육종, 난소암, 췌장암, 유두종증, 부신경절종, 부비동암과 비강암, 부갑상선암, 음경암, 인두암, 크롬친화성세포종, 뇌하수체암, 형질 세포 신생물, 흉막폐 모세포종, 임신성 유방암, 원발성 중추신경계 림프종, 원발성 복막암, 전립선암, 직장암, 신장 세포 암, 망막모세포종, 횡문근육종, 타액선암, 육종, 세자리 증후군, 피부암, 소세포 폐암, 소장암, 연조직 육종, 편평상피 세포 암종, 편평상피 경부암, 위암, T-세포 림프종, 고환암, 인후암, 흉선종과 흉선 암종, 갑상선암, 신우와 요관의 이행 세포 암, 원발 병소 불명 암종, 요도암, 자궁암, 자궁 육종, 질암, 외음부암, 발덴스트롬 마크로글로불린혈증, 그리고 윌름 종양을 포함한다. 일부 사례에서, 본원에서 설명된 재료와 방법은 난소암을 확인하고 및/또는 치료하는데 이용될 수 있다.
다른 양상에서, 본 문서는 또한, 포유동물이 질환 및/또는 병기를 겪는 것으로 확인하는데 이용될 수 있는 펩티드 생물마커 (예를 들면, 순환하는 펩티드 생물마커)를 확인하고 및/또는 검증하기 위한 방법과 재료를 제공한다. 일부 사례에서, 본원에서 제공된 방법과 재료는 포유동물이 암을 겪는 것으로 확인하는데 이용될 수 있는 펩티드 생물마커 (예를 들면, 순환하는 펩티드 생물마커)를 확인하고 및/또는 검증하는데 이용될 수 있다.
본원에서 설명된 방법과 재료는 펩티드 생물마커 (예를 들면, 순환하는 펩티드 생물마커)를 확인하는데 이용될 수 있다. 일부 사례에서, 순환하는 펩티드 생물마커를 확인하기 위한 방법은 대조 표본 (예를 들면, 참조 표본)과 비교하여 질환 표본에서 상승되는 순환하는 펩티드 생물마커를 확인하는 단계를 포함할 수 있다. 일부 사례에서, 질환 표본은 질환을 겪는 한 마리 또는 그 이상 (예를 들면, 2, 3, 5, 8, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 25, 30, 35, 40, 50, 60, 70, 80, 90, 100마리 또는 그 이상)의 포유동물로부터 획득된 혈액을 포함할 수 있다. 일부 사례에서, 질환 표본은 단일 포유동물로부터 획득된 혈액을 포함할 수 있다. 일부 사례에서, 대조 표본은 한 마리 또는 그 이상 (예를 들면, 2, 3, 5, 8, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 25, 30, 35, 40, 50, 60, 70, 80, 90, 100마리 또는 그 이상)의 건강한 포유동물 (예를 들면, 질환을 겪지 않는 포유동물)로부터 획득된 혈액을 포함할 수 있다. 일부 사례에서, 대조 표본은 단일 포유동물로부터 획득된 혈액을 포함할 수 있다. 일부 사례에서, 하나 또는 그 이상의 순환하는 펩티드 생물마커를 확인하기 위한 방법은 질환 혈액 표본 내에 존재하는 폴리펩티드를 펩티드 단편으로 소화시켜 질환 펩티드 단편의 표본을 획득하는 단계; 그리고 참조 혈액 표본 내에 존재하는 폴리펩티드를 펩티드 단편으로 소화시켜 참조 펩티드 단편의 표본을 획득하는 단계를 포함할 수 있다. 일부 사례에서, 소화된 표본으로부터 펩티드 단편 (예를 들면, 질환 펩티드 단편 또는 참조 펩티드 단편)은 차별적으로 표지화될 수 있다. 예를 들면, 질환 혈액 표본으로부터 펩티드 단편은 표지 없이 남아있을 수 있고, 그리고 참조 표본으로부터 펩티드 단편은 중동위원소로 표지화될 수 있고, 또는 그 반대일 수 있다. 예를 들면, 질환 혈액 표본으로부터 펩티드 단편 및 참조 표본으로부터 펩티드 단편은 상이한 중동위원소로 표지화될 수 있다. 일부 사례에서, 상이한 질환 (예를 들면, 상이한 암 유형) 또는 상이한 병기 (예를 들면, 첫 번째 질환 표본은 초기 질환 표본이고, 그리고 두 번째 질환 표본은 진행된 질환 표본이다)로부터 하나 또는 그 이상 (예를 들면, 2, 3, 4, 5개, 또는 그 이상)의 표본이 이용될 수 있고, 그리고 각 표본 (예를 들면, 각 질환 표본 및 대조 표본)은 각각, 상이한 중동위원소로 표지화될 수 있다. 중동위원소의 실례는 제한 없이, 중수소, C13, N15 및 O18을 포함한다. 질환 혈액 표본으로부터 펩티드 단편 및 참조 표본으로부터 펩티드 단편이 표지화되지 않을 때, 이들 질환 펩티드 단편 및 참조 펩티드 단편은 질량 분광분석법에 종속될 수 있고 (예를 들면, 별개의 실행으로서 질량 분광분석법에 독립적으로 종속될 수 있고), 그리고 하나 또는 그 이상의 펩티드 생물마커 (예를 들면, 참조 표본에 비하여 질환 표본에서 상승되는 펩티드)를 확인하기 위해, 그 결과가 비교될 수 있다. 질환 혈액 표본으로부터 펩티드 단편 및 참조 표본으로부터 펩티드 단편이 차별적으로 표지화될 때, 하나 또는 그 이상의 펩티드 생물마커 (예를 들면, 참조 표본에 비하여 질환 표본에서 상승되는 펩티드)를 확인하기 위해, 표지화된 질환 펩티드 단편 및 표지화된 참조 펩티드 단편이 질량 분광분석법에 종속될 수 있다 (예를 들면, 단일 질량 분광분석법 실행으로서).
임의의 적합한 질량분광계가 이용될 수 있다. 질량분광계의 실례는 제한 없이, Orbitrap 질량분광계 및 삼중 4극 질량분광계, 비행 시간 (TOF), 매트릭스-보조된 레이저 탈착/이온화 (MALDI) -TOF, 그리고 표면-증강된 레이저 탈착/이온화 (SELDI) -TOF를 포함한다. 예를 들면, 본원에서 설명된 바와 같이 하나 또는 그 이상의 펩티드 생물마커를 확인할 때, Orbitrap 질량분광계가 이용될 수 있다.
폴리펩티드를 소화하기 위한 임의의 적합한 방법이 이용될 수 있다. 일부 사례에서, 폴리펩티드는 효소적으로 소화될 수 있다. 일부 사례에서, 폴리펩티드는 화학적으로 소화될 수 있다. 예를 들면, 폴리펩티드는 제한 없이, Arg-C, Asp-N, Asp-N (N 말단 Glu), BNPS 또는 NCS/요소, 카스파제-1, 카스파제-10, 카스파제-2, 카스파제-3, 카스파제-4, 카스파제-5, 카스파제-6, 카스파제-7, 카스파제-8, 카스파제-9, 키모트립신, 키모트립신 (낮은 특이성), 클로스트리페인, CNBr, CNBr (메틸-Cys), CNBr (산과 함께), 엔테로키나아제, 인자 Xa, 포름산, Glu-C (AmAc 완충제), Glu-C (Phos 완충제), 그랜자임 B, HRV3C 프로테아제, 히드록실아민, 요도오소벤조산, Lys-C, Lys-N, Lys-N (Cys 변형됨), 약산 가수분해, NBS (긴 노출), NBS (짧은 노출), NTCB, 췌장 엘라스타아제, 펩신 A, 펩신 A (낮은 특이성), 프로릴 엔도펩티다아제, 단백질분해효소 K, TEV 프로테아제, 서몰리신, 트롬빈, 트립신 및/또는 가수분해를 이용하여 소화될 수 있다.
일부 사례에서, 하나 또는 그 이상의 순환하는 펩티드 생물마커를 확인하기 위한 방법은 높은 존재비로 존재하는 순환 단백질을 질환 표본 및/또는 대조 표본으로부터 감소시키거나 또는 제거하는 단계를 포함할 수 있다. 높은 존재비로 존재하는 순환 단백질의 실례는 제한 없이, 알부민, 면역글로불린 (예를 들면, IgG, IgA 및 IgM), α1-항트립신, 트랜스페린, 합토글로빈, α2-마크로글로불린, 피브리노겐, 보체 C3, α1-산 당단백질 (오로소뮤코이드), 고밀도 지질단백질 (HDLs; 예를 들면, 아포지질단백질 A-I 및 A-II), 그리고 낮은 밀도 지질단백질 (LDLs; 예를 들면, 아포지질단백질 B)을 포함한다. 높은 존재비로 존재하는 순환 단백질은 임의의 적합한 기술을 이용하여 감소되거나 또는 제거될 수 있다. 순환 단백질은 임의의 적합한 기술을 이용하여 감소되거나 또는 제거될 수 있다. 순환 단백질을 감소시키거나 또는 제거하기 위한 수단의 실례는 제한 없이, 시바크론 블루 염료 및 항체-기초된 혈장 고갈을 포함한다. 예를 들면, 높은 존재비로 존재하는 순환 단백질은 항체-기초된 혈장 고갈에 의해 감소되거나 또는 제거될 수 있다.
일부 사례에서, 하나 또는 그 이상의 순환하는 펩티드 생물마커를 확인하기 위한 방법은 낮은 존재비로 존재하는 순환 단백질을 질환 표본 및/또는 대조 표본으로부터 농축하는 단계를 포함할 수 있다. 예를 들면, 낮은 존재비 단백질은 펩티드 리간드 라이브러리 (참조: 예를 들면, ProteoMiner 단백질 농축 키트에서 전략)를 이용하거나 또는 앱타머를 이용하여 농축될 수 있다.
일부 사례에서, 하나 또는 그 이상의 순환하는 펩티드 생물마커를 확인하기 위한 방법은 질환 혈액 표본 및/또는 대조 표본으로부터 펩티드 단편을 변성시키고, 환원시키고 및/또는 알킬화하는 단계를 포함할 수 있다. 예를 들면, 펩티드는 요소, 황산도데실나트륨 (SDS), 메탄올, 글리세롤 및/또는 열을 이용하여 변성될 수 있다. 예를 들면, 펩티드는 트리스-(2-카르복시에틸)포스핀 (TCEP), 디티오트레이톨 (DTT) 및/또는 2-메르캅토에탄올을 이용하여 환원될 수 있다. 예를 들면, 펩티드는 메틸 메탄티오술포네이트 (MMTS), 요오드아세트아미드 및/또는 요오드아세트산염을 이용하여 알킬화될 수 있다.
일부 사례에서, 하나 또는 그 이상의 순환하는 펩티드 생물마커를 확인하기 위한 방법은 각 표본에서 당단백질, 인산화된 단백질 및/또는 다른 번역후 변형을 보유하는 단백질을 농축하는 단계를 포함할 수 있다.
본원에서 설명된 방법과 재료는 펩티드 생물마커 (예를 들면, 순환하는 펩티드 생물마커)를 검증하는데 이용될 수 있다. 일부 사례에서, 하나 또는 그 이상의 순환하는 펩티드 생물마커를 검증하기 위한 방법은 본원에서 설명된 임의의 다양한 방법에 따라서 확인된 순환하는 펩티드 생물마커를 검증하는 단계를 포함할 수 있다. 펩티드 생물마커 (예를 들면, 순환하는 펩티드 생물마커)를 검증하기 위한 방법은 분획된 용출물의 선별된 반응 모니터링 SRM (SAFE-SRM)에 의한 순차적 분석을 포함할 수 있다. 일부 사례에서, 펩티드 생물마커는 미리 최적화된 트랜지션 및/또는 미리 최적화된 체류 시간 (예를 들면, 이러한 펩티드 생물마커의 강도를 결정하기 위한)을 포함하는 SRM 방법을 이용하여 검증될 수 있다. 일부 사례에서, 펩티드 생물마커는 이러한 펩티드 생물마커의 강도를 결정하기 위한 최적화된 트랜지션 및/또는 최적화된 체류 시간을 갖는 SRM 방법을 구축함으로써 검증될 수 있다. 예를 들면, 후보 펩티드 생물마커의 각 세트에 대해, 한 세트의 SAFE-SRM 방법이 집성될 수 있다. 실시예 1에서 증명된 바와 같이, 각 후보 생물마커의 합성 펩티드는 염기성 pH 역상 액체 크로마토그래피 (bRPLC)에 종속되어 분획물 군이 산출될 수 있다. 합성 펩티드의 분획물 군은 어떤 합성 펩티드가 어떤 군에 위치되는 지를 결정하고, 그리고 이와 동시에, 이의 군 내에서, 펩티드의 표준 강도 (초기에 이용된 일정한 양으로부터 도출된 바와 같이)를 결정하기 위해 질량 분광분석법에 종속될 수 있다 (참조: 예를 들면, 도 5). 펩티드 생물마커는 예를 들면, 이러한 펩티드 생물마커가 본원에서 설명된 SAFE-SRM 방법을 이용하여, 참조 표본에 비하여 질환 표본에서 상승된 수준에서 검출되고 정량될 때 검증될 수 있다.
일부 사례에서, 펩티드 생물마커를 검증하기 위한 방법 (예를 들면, SAFE-SRM을 이용)은 하나 또는 그 이상의 펩티드 생물마커를 bRPLC (예를 들면, 높은 pH에서 bRPLC)에 종속시켜 복수의 분획물 (예를 들면, 5, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200개 또는 그 이상의 분획물)을 획득하는 단계; 복수의 분획물을 복수의 분획물 군 (예를 들면, 2, 3, 5, 10, 15, 20, 25, 30, 35, 40, 45, 50개 또는 그 이상의 분획물 군)으로 조직화하는 단계; 각 분획물 군에서 펩티드 생물마커를 산성 pH (낮은 pH)에서 직교 HPLC에 의해 분리하여 연속 HPLC 용리액을 획득하는 단계; 그리고 SRM 방법을 이용하여 연속 HPLC 용리액을 분석하는 단계를 포함할 수 있고, 여기서 펩티드 생물마커는 이러한 펩티드 생물마커에 대해 최적화된 충돌 에너지와 체류 시간이 관찰될 때 검증된다. 일부 사례에서, SRM 방법은 상기 분획물 군에서 용리된 합성 펩티드로 미리 확립될 수 있다. 일부 사례에서, 복수의 분획물은 48, 96 또는 384개의 분획물을 포함한다. 일부 사례에서, 복수의 분획물 군은 16, 32 또는 124개의 분획물 군을 포함한다.
일부 사례에서, 펩티드 생물마커를 검증하기 위한 방법 (예를 들면, SAFE-SRM을 이용)은 HPLC를 질량분광계에 연계하는 단계를 포함할 수 있다. 임의의 적합한 질량분광계가 이용될 수 있다. 질량분광계의 실례는 제한 없이, Orbitrap 질량분광계, 삼중 4극 질량분광계, TOF, MALDI-TOF, 그리고 SELDI-TOF를 포함한다. 예를 들면, 본원에서 설명된 바와 같이 하나 또는 그 이상의 펩티드 생물마커를 검증할 때, 삼중 4극 질량분광계에 연계될 수 있는 HPLC가 이용될 수 있다.
일부 사례에서, 펩티드 생물마커를 검증하기 위한 방법 (예를 들면, SAFE-SRM 이용)은 각 펩티드 생물마커에 대한 트랜지션 파라미터를 구축하는 단계를 포함할 수 있다. 예를 들면, 트랜지션은 제한 없이, 선구 이온 m/Z, 생성 이온 m/Z, 충돌 에너지 및/또는 체류 시간의 파라미터를 포함할 수 있다. 트랜지션은 특정한 선구 이온-생성 이온 쌍에 대해 최적화될 수 있다. 예를 들면, 전구체인 각 펩티드는 단편화된 후 복수의 생성 이온을 가질 수 있고, 그리고 각 생성 이온은 그 자체의 최적화된 충돌 에너지와 체류 시간을 가질 수 있다. 일부 사례에서, 체류 시간을 최적화하는 것은 이들 트랜지션을 높은 pH에서 그들의 소수성에 따라서 재조립하는 것을 포함할 수 있다 (참조: 예를 들면, 실시예 1 및 도 5). 일부 사례에서, 체류 시간을 최적화할 때, 어떤 펩티드가 더욱 긴 체류 시간에서 검출될 필요가 있을 수 있는 지를 결정하기 위해, 상이한 표적 펩티드가 대략 동일한 양에서 스파이킹될 수 있다. 각 펩티드는 여러 트랜지션을 가질 수 있는데, 여기서 각 트랜지션은 선구 이온-생성 이온 쌍에 상응한다. 일부 사례에서, 트랜지션은 합성 펩티드를 이용하여 각 표적 펩티드에 대해 최적화될 수 있다. 일부 사례에서, 트랜지션 파라미터는 데이터세트 S5에서 진술된 바와 같을 수 있다.
일부 사례에서, 다양한 표본을 분석할 때 bRPLC 체류 시간의 잠재적인 변동의 균형을 잡기 위해, 임의의 소정의 분획물 전후의 분획물이 분석될 수 있다.
일부 사례에서, 펩티드 생물마커를 검증하기 위한 방법 (예를 들면, SAFE-SRM을 이용)은 합성 펩티드로 확립될 수 있다.
일부 사례에서, 펩티드 생물마커를 검증하기 위한 방법 (예를 들면, SAFE-SRM을 이용)은 가벼운 펩티드 (예를 들면, 중동위원소로 표지화되지 않는 펩티드)로 확립될 수 있다. 가벼운 펩티드의 이용은 임의의 다양한 이유로 유리할 수 있다. 예를 들면, 가벼운 펩티드는 일반적으로, 생산 비용이 더욱 적고, 그리고 따라서 이들의 이용은 특히, 수백 개 또는 수천 개의 생물마커가 검증되어야 하는 생물마커 개발의 초기 단계에서 무거운 펩티드를 이용할 때 소요되는 높은 비용을 감소시킨다. 중동위원소-표지화된 펩티드는 또한, 이온 억제를 야기하고, 따라서 민감도를 훼손할 수 있다.
본원에서 설명된 방법과 재료는 펩티드 생물마커 (예를 들면, 순환하는 펩티드 생물마커)를 확인하는 것, 그리고 펩티드 생물마커를 검증하는 것 (예를 들면, SAFE-SRM을 이용) 둘 모두에 이용될 수 있다.
본 발명은 하기 실시예에서 더욱 설명될 것인데, 이들 실시예는 청구항에서 설명된 발명의 범위를 제한하지 않는다.
실시예
실시예 1: 후보 생물마커를 검증하기 위한 선별된 반응 모니터링 접근법
본 실시예에서는 후보 펩티드의 대량 목록을, 정량, 민감도 또는 특이성을 훼손하지 않는 더욱 관리가능한 목록으로 좁힐 수 있는 고유한 생물마커를 개발하기 위한 펩티드-중심 플랫폼을 설명한다. 본 실시예서는 암 조직으로부터 보다는 혈장으로부터 직접적으로 단리된 펩티드가 고유한 암 생물마커의 발견에 이용될 수 있다는 것을 더욱 보여준다.
재료와 방법
혈장 표본. 96명의 건강한 개체, 81명의 난소암 환자, 51명의 췌장암 환자, 그리고 38명의 결장직장암 환자를 포함하는 총 266명의 개체로부터 혈장 표본이 획득되었다. 이들 혈장 표본 및 임상 데이터는 적절한 기관 감사 위원회 승인 후, The Ontario Tumor Bank, Indivumed, Innovative Research, 그리고 The Johns Hopkins Hospital로부터 획득되었다. 266명 환자의 선별된 임상적 특질 및 이들의 종양의 조직병리학적 특징은 데이터세트 S1에서 열거된다.
재료와 시약. 인간 혈장 고갈 Seppro IgY14 LC10 칼럼 시스템은 Sigma-Aldrich로부터 구입되었다. 트리스-(2-카르복시에틸)포스핀 (TCEP) 및 메틸 메탄티오술포네이트 (MMTS)는 Thermo Fisher Scientific로부터 구입되었다. LysC 및 트립신 프로테아제는 Promega로부터 구입되었다. PNGase F는 New England Biolabs로부터 구입되었다. TiO2 농축을 위한 타이탄스피어, 10 또는 5 μm은 GL Sciences로부터 획득되었다. CA19-9와 CA125 항체는 Fujirebio Diagnostics로부터 구입되었다. 강한 양이온 교환 (SCX) 크로마토그래피를 위한 폴리술포에틸 A 칼럼 (100 x 2.1 mm, 5 μm, 200 Å)은 PolyLC로부터 구입되었다. 표본 준비를 위한 C18 카트리지 및 삼중 4극 질량분광계의 bRPLC와 온라인 HPLC를 위한 크로마토그래피 칼럼은 Waters로부터 구입되었다. 모든 iTRAQ 시약과 완충액은 AB Sciex로부터 구입되었다. 합성 펩티드는 Genscript로부터 구입되었다. 모든 다른 시약은 별도로 지시되지 않으면, Sigma-Aldrich로부터 구입되었다.
용액의 제조. SCX 용매 A는 10 mM KH2PO4, 25% (vol/vol) 아세토니트릴을 내포하였고; SCX 용매 B는 10 mM KH2PO4, 350 mM KCL, 25% (vol/vol) 아세토니트릴을 내포하였고; 그리고 양쪽 SCX 용매에 대해, 50% H3PO4를 첨가함으로써 pH 2.75가 달성되었다. bRPLC 용매 A는 10 mM TEABC를 내포하였고; bRPLC 용매 B는 10 mM TEABC, 90% (vol/vol) 아세토니트릴을 내포하였다. SAFE-SRM MS 용매 A는 0.1% (vol/vol) 포름산을 포함하는 물이었고; SAFESRM 용매 B는 0.1% (vol/vol) 포름산을 포함하는 아세토니트릴이었다.
iTRAQ-기초된 발견 연구를 위한 한데 모아진 혈장 표본. 50명의 정상적인 개체, 13명의 췌장암 환자, 18명의 결장직장암 환자, 그리고 18명의 난소암 환자가 초기 분석을 위해 선택되었다. 본 연구의 1 단계의 절차를 밟기 전, 이들 4가지 환자 군 중에서 한 가지에서 각 개체로부터 100 마이크로리터의 혈장이 모아졌다. 본 연구의 1 단계에는 개별 환자로부터 펩티드보다는, "한데 모아진 펩티드"로서 지칭되는 이들 풀이 이용되었다.
혈장 고갈. 혈장 내에 풍부한 단백질 [알부민, IgG, α1-항트립신, IgA, IgM, 트랜스페린, 합토글로빈, α2-마크로글로불린, 피브리노겐, 보체 C3, α1-산 당단백질 (오로소뮤코이드), HDL (아포지질단백질 A-I 및 A-II), 그리고 LDL (주로 아포지질단백질 B)]이 Seppro IgY14 LC10 칼럼 시스템을 이용하여 고갈되었다. 혈장 표본은 IgY 희석 완충액에서 5x 희석되고, 여과되고 (0.22 μm), 그리고 이후, 바이너리 펌프, 외부 표본 주입기, UV 검출기 및 분획물 수집기로 구성되는 Agilent 1200 HPLC 시스템에 부착된 IgY LC10 칼럼 내로 주입되었다. 비보유된 분획물은 수집되었다.
혈장 단백질체 표본 준비. 고갈된 혈장 단백질은 9 M 요소에서 변성되고, 60 ℃에서 15 분 동안 5 mM TCEP를 이용하여 환원되고, 그리고 시스테인 잔기가 어둠 하에 실온에서 15 분 동안 5 mM MMTS로 알킬화되었다. 알킬화된 단백질 용액은 Ultracel-10 막 (Millipore)을 갖는 Amicon Ultra-15 원심 필터 단위를 이용한 여과에 의해 탈염되고 9M 요소로 2회 세척되었고, 그리고 탈염된 혈장 단백질은 4 mL의 40 mM TEABC로 재구성되었다. 표본은 이후, LysC 프로테아제로 3 시간 동안 소화되고, 그 이후에 37 ℃에서 서열 분석 등급 트립신을 이용하여 하룻밤 동안 소화되었다. 소화가 종결되기 3 시간 전에 추가 서열 분석 등급 트립신이 첨가되었고, 그리고 상기 소화 시스템은 반응을 중단시키기 위한 1% TFA를 첨가하기 전 마지막 30 분 동안 50 ℃에서 배양되었다. 소화물의 C18-매개된 청소가 다른 곳에서 설명된 바와 같이 수행되었다 (참조: 예를 들면, Howlader et al. 2014 SEER Cancer Statistics Review, 1975-2011 (National Cancer Institute, Bethesda)). iTRAQ 실험에서 이용되지 않은 표본, 다시 말하면, 한데 모아진 혈장 표본보다는 개별 공여자로부터 것들의 경우에, MMTS보다는 50 mM 요오드아세트아미드 (Sigma-Aldrich)가 알킬화에 이용되었다.
인간 혈장 표본으로부터 N-글리코실화된 단백질 농축과 단리. 100 마이크로리터의 한데 모아진 인간 혈장 표본은 9 M 요소에서 변성되고, 환원, 알킬화 및 여과를 통해 처리되어 염이 제거되고, 그리고 이후, 동결 건조에 종속되었다. 동결 건조된 단백질은 0.1% TFA를 포함하는 5% 아세토니트릴로 재구성되었다. 10 mM 과요오드산나트륨이 단백질 용액에 적용되었고, 그 이후에 어둠 하에 4 ℃에서 1 시간 동안 배양되었다. 산화된 단백질을 정제하기 위해 추가 C8 카트리지 청소가 수행되었다. 동결 건조된 단백질은 1 mL의 히드라지드 수지 연계 완충액 (0.1 M 인산나트륨 완충액, pH 7.0)으로 재구성되었고, 그리고 실온에서 5 시간 동안 배양에 의해 당단백질체를 접합시키기 위해, Bio-Rad로부터 구입된 250 μL의 히드라지드 수지가 용액에 첨가되었다. 상기 수지는 이후, 4 mL의 1.5 M NaCl, 그 이후에 4 mL의 물로 2회, 4 mL의 100 mM TEABC 완충액으로 2회, 그리고 최종적으로 4 mL의 50 mM 인산나트륨 (pH 7.5)으로 세척되었다. 25 마이크로리터의 PNGase F가 상기 수지에 첨가되고, 그 이후에 교반하면서 37 ℃에서 4 시간 동안 배양되었다. 상기 수지는 이후, 8,000 x g에서 5 분 동안 원심분리되었고, 그리고 상층액이 수집되었다. 수지 펠렛은 500 μL의 40 mM 중탄산암모늄으로 2회 세척되고 상기와 같이 원심분리에 종속되었다. 이들 원심분리로부터 상층액은 조합되고, 동결 건조되고, 40 mM 중탄산암모늄으로 재구성되고, 그리고 트립신 소화 및 C18 청소에 종속되었고, 그 후 이들은 iTRAQ 표지화에 이용되었다. 총 657개의 글리코실화된 단백질이 확인되고 정량되었다 (데이터세트 S3). N-글리코실화된 단백질 농축 실험으로부터 29개의 단백질이 확인되었는데, 이들은 본 연구의 검증 단계로 이월되었다.
iTRAQ 표지화, SCX 청소, 그리고 bRPLC 분별. 4개의 풀로부터 펩티드는 15 μL의 H2O 및 20 μL의 용해 완충액 (iTRAQ 표지화 키트와 함께 제공됨)에서 재구성되고, 그리고 실온에서 70 μL의 에탄올에서 희석된 4가지 iTRAQ 시약 중에서 한 가지와 함께 배양되었다. 4개의 풀 각각으로부터 펩티드는 각각, 114, 115, 116 또는 117개의 리포터 이온을 내포하는 iTRAQ 시약으로 표지화되었다. 실온에서 2 시간 동안 배양 후, 50 μL의 물이 첨가되었다. 실온에서 10 분 동안 추가 배양 후, 100 μL의 물이 첨가되었다. 실온에서 추가로 10 분 동안 배양 후, 40 μL의 40 mM 중탄산암모늄이 이후 첨가되었고, 그리고 반응물은 4 ℃에서 하룻밤 동안 배양되었다. 표본은 50 μL로 진공 건조되고, 조합되고, 그리고 25% 아세토니트릴을 내포하는 10 mM 인산칼륨 완충액 (pH 2.7) (SCX 용매 A)에서 4 mL로 희석되었다. 표본의 pH는 100 mM 인산을 이용하여 2.7로 조정되었다. iTRAQ-표지화된 펩티드는 이후, Agilent 1200 HPLC 시스템 상에서 폴리술포에틸 A 칼럼 (PolyLC) (300 Å, 5 μm, 100 x 2.1 mm)을 갖는 SCX 크로마토그래피를 이용하여 정제되었다 (참조: 예를 들면, Fishman et al. 2005 Am J Obstet Gynecol 192:1214-1221). SCX 용매 B에서 0으로부터 350 mM KCl로 증가하는 염 농도의 선형 구배를 이용하여, 분별이 45 분의 기간 동안 실행되었다. 펩티드 분획물은 이후, 진공 건조되고, 4 mL의 bRPLC 용매 A로 재구성되고, 그리고 XBridge C18 칼럼 (Waters)을 이용한 bRPLC 분별에 종속되었다. bRPLC로부터 총 96개의 분획물이 96-웰 평판에 축적되었다.
혈장 펩티드 준비. 각 개체로부터 200-μL 혈장 표본이 전술된 절차를 이용하여 처리되었다. 동결 건조된 혈장 펩티드 표본은 3% 아세토니트릴을 포함하는 2 mL의 10 mM 트리에틸중탄산암모늄 (pH 8.2)에서 재구성되었다. 펩티드 분별이 높은 pH에서, C18 칼럼을 갖는 Agilent 1260 HPLC 시스템에서 수행되었다. 2가지 HPLC 이동상 용매는 10 mM 트리에틸중탄산암모늄 (용매 A), 그리고 90% 아세토니트릴을 포함하는 10 mM 트리에틸중탄산암모늄 (용매 B)이었다. 120-분 HPLC 구배 법이 염을 제거하기 위해 첫 20 분 동안의 수세 단계로 적용되었고, 그리고 이것에 뒤이어, 0으로부터 100%로 증가하는 용매 B로 96-분 구배가 이어졌다. 혈장 펩티드 표본으로부터 96개의 분획물이 단백질 LoBind 평판 (에펜도르프)에서 수집되었고, 그리고 각 1-분 윈도우 동안 용리된 펩티드가 각 웰에서 수집되었다. 펩티드 분획물은 도 5A에서 도시된 계획에 따라서 조합되고 진공 건조되었다. 건조된 펩티드는 이후, 40 μL의 SRM 용매 A를 이용하여 재구성되고, 그리고 Agilent 1290 UHPLC 시스템에서 추가 온라인 분별 전, 3 fmol의 중동위원소-표지화된 K-Ras 야생형 (WT) 펩티드 (LVVVGAGGVGK*; 서열 번호:23)로 스파이킹되었다. 온라인 UHPLC는 각 표본을 낮은 pH (pH 3)에서 분별하였는데, 이것은 높은 pH (pH 8.2)에서 수행되는 첫 번째 HPLC 분별과 극적으로 상이한 분별 프로필을 창출하였다. 분별된 표본은 SRM 양이온 방식에서 작동된 Agilent 6490 삼중 4극 질량분광계의 Jet Stream ESI 소스 내로 연속적으로 주입되었다.
정상적인 표본 및 암 혈장 표본에 대한 정량적 단백질체학 검정. 정상적인 혈장 및 암 혈장 표본 사이에 프로테오믹 차이를 평가하기 위해, iTRAQ 표지화-의존성 정량적 단백질체학 검정이 수행되었다. 이러한 파이프라인은 혈장 고갈, 변성, 환원, 알킬화, 당단백질에 대한 농축, 트립신 소화, 탈염, iTRAQ 표지화, 강한 양이온 교환 (SCX) 청소 및 bRPLC 분별, 그 이후에 Orbitrap MS 분석 및 인하우스-개발된 R 스크립트를 이용한 정량적 단백질체학 데이터 분석을 포함하였다.
액체 크로마토그래피-MS/MS 및 혈장 정량적 단백질체학 데이터 분석. iTRAQ-표지화된 bRPLC-분리된 표본의 나노흐름 전기분무 이온화 액체 크로마토그래피 (LC)-MS/MS 분석이 Eksigent 나노-LC에 의해 제어되는 역상 시스템 및 Agilent 1100 마이크로웰 평판 자동샘플러와 접속된 LTQ Orbitrap Velos (Thermo Fisher Scientific) 질량분광계로 수행되었다. bRPLC 분획물은 75 μm x 2 cm, Magic C18AQ 칼럼 (5 μm, 100 Å; Michrom Bioresources)을 통해 순차적으로 처리되고, 그리고 이후, 나노흐름 용매 전달로 분석적 칼럼 (75 μm x 10 cm, Magic C18AQ, 5 μm, 100 Å; Michrom Bioresources)에서 분리되었다. 이동상 유속은 200 nL/분이고 3% 아세토니트릴/0.1% 포름산 (용매 A) 및 90% 아세토니트릴/0.1% 포름산 (용매 B)으로 구성되었고, 그리고 110-분 LC-MS/MS 방법은 10-분 칼럼 평형화 절차, 10-분 표본-부하 절차 및 하기의 구배 프로필로 구성되었다: (분:B%) 0:0; 2:6; 72:40%; 78:90%; 84:90%; 87:50%; 90:50%(마지막 3 단계는 500 nL/분 유속에서). MS 및 MS/MS 데이터는 2.5 kV의 분무 전압에서 및 m/z 400에서 60,000의 해상도에서 양이온 방식으로 획득되었다. 모든 작동 주기에 대해, 10개의 가장 풍부한 펩티드 전구체가 LTQ Orbitrap Velos에서 MS/MS 분석을 위해 선택되었다 (정규화된 충돌 에너지, 40%). iTRAQ-기초된 정량적 단백질체학의 상세한 흐름도가 도시된다 (도 4A).
정량적 단백질체학 분석. iTRAQ 실험으로부터 MS 데이터는 Proteome Discoverer (버전 2.1; Thermo-Fisher)로 분석되었다. MS/MS 스펙트럼 데이터는 MASCOT 및 상기 프로그램의 Sequest HT 검색 성분 하에 특질 추출을 이용하여 처리되었다. 양쪽 성분에 대해, 동일한 검색 파라미터가 선택되었고, 그리고 이들은 티로신에서 iTRAQ 표지, 메티오닌의 산화, 그리고 N/Q에서 탈아미드화를 가변적 변형으로서 포함하였다. N 말단에서 iTRAQ 표지, 그리고 시스테인에서 리신, 메틸티오 표지는 고정된 변형으로서 이용되었다. MS 데이터는 55,692개의 서열을 내포하는 NCBI RefSeq 72 인간 단백질 데이터베이스에 대해 검색되었다. Proteome Discoverer은 단백질 엔트리의 역 서열을 내포하는 별개의 미끼 데이터베이스 (역 데이터베이스)를 이용하여 가성 확인의 백분율을 계산한다. Proteome Discoverer은 양쪽 검색으로부터 정합의 숫자를 계수하고, 그리고 단지 하나의 펩티드만 정확한 정합일 수 있다는 가정 하에, 스펙트럼마다 단지 상위 정합만을 계수함으로써 오류 발견율 (FDR)을 계산한다. 이들 점수 역치는 정방향 히트와 비교하여 1%와 5% 역방향 히트가 획득되어, 5%의 전체 FDR이 발생하도록 조정되었다. 선구 이온 및 리포터 이온 윈도우 허용오차는 각각, 20 ppm 및 0.05 Da에서 고정되었다. 피크 목록의 산출을 위한 특정된 기준은 1.5의 신호 대 잡음 비율을 포함하고 600-8,000 Da의 전구체 질량 범위를 포함하였다. PPIA 단백질로부터 2개의 검증된 SAFE-SRM 표적 펩티드는 도 8에서 도시된 바와 같이, 1% FDR 컷오프를 이용하여 초기에 분명하게 확인되었다.
추가 검증을 위한 잠재적인 암 생물마커로서 641개 펩티드의 선별. 총 204개의 단백질이 3개의 전체-혈장 iTRAQ 단백질체학 데이터세트 중에서 적어도 2개에 의해 공유되었다. 이들 단백질 중에서 87개가 경험적 변형된 eBayes t 검정에서 그들의 존재비 검사 점수에 근거하여, 추가 SRM-기초된 검증을 위한 잠재적인 암 생물마커로서 선별되었다. 이들 단백질로부터 총 461개의 프로테오타이픽 펩티드가 SRM 정량화 표적 (단백질마다 대략 5개의 표적 펩티드)으로서 선별되었다. 이들 461개 펩티드 중에서, 208개는 우리의 실험에서 직접적으로 관찰되었고, 그리고 다른 253개 펩티드는 PeptideAtlas, PRIDE 등을 비롯한 여러 데이터베이스를 조회하는 것으로부터 추가되었다 (참조: 예를 들면, Desiere et al. 2006 Nucleic Acids Res 34:D655-D658; Wang et al. 2011 Proc Natl Acad Sci USA 108:2444-2449; 및 Vizca
no et al. 2016 Nucleic Acids Res 44:D447-D456). 우리는 또한, 우리의 iTRAQ 데이터세트에서 초기 선별을 위한 우리의 엄격한 기준에는 부합하지 못하지만 생물학적 성질에 근거하여 합리적인 후보 생물마커인 것으로 고려되는 180개의 펩티드를 확인하였다. 종합하면, 우리는 우리의 연구의 1 단계로부터 641개의 SRM 표적 펩티드를 선별하였고, 이들은 검증 단계로 이월되었다 (데이터세트 S4).
R/Bioconductor에서 limma 패키지를 이용한 펩티드 정량의 통계학적 분석. 114 (정상적인 개체 풀)의 것에 비하여 iTRAQ 표지화 117 (췌장암 풀), 116 (결장직장암 풀) 또는 115 (난소암 풀)의 펩티드 이온 강도의 중앙값에 기초하여, 한데 모아진 표본의 펩티드 발현 비율이 계산되었다. 표본 준비는 이중으로 수행되었다 (2개의 생물학적 복제물). MS 분석은 첫 번째 복제물에서 1회 수행되고 (데이터세트 1 산출), 그리고 두 번째 복제물에서 2회 수행되어, 데이터세트 2와 3이 산출되었는데, 이들은 이런 이유로 기술적인 복제물이다. 미가공 펩티드 존재비 데이터를 보관하기 위한 행렬이 산출되었는데, 여기서 열 명칭은 이들 펩티드 중에서 모든 특이 서열을 내포하였다. 칼럼 1 내지 4는 데이터세트 1로부터 114, 115, 116 및 117 표지화 강도의 강도를 보관하였다. 칼럼 5 내지 8 및 칼럼 9 내지 12는 각각, 데이터세트 2와 3으로부터 유사한 표지화 강도를 보관하였다. "해당 없음 (NA)"은 펩티드가 특정 표지를 갖는 특정 데이터세트에서 검출되지 않는다는 것을 지시하는데 이용되었다 (데이터세트 S2).
상이한 데이터세트 사이에 잠재적인 편향을 비교하기 위한 MA 플롯이 산출되었다. 이들 MA 플롯에서 어떤 유의미한 편향도 관찰되지 않았기 때문에 (도 9), 중앙값 정규화가 차후 분석을 위해 선택되었다 (도 10). 이러한 분석을 위해, 우리는 마이크로어레이 데이터의 분석을 위해 개발된 개념을 차용하고, 그리고 펩티드 배수 변화를 분석하기 위해 Bioconductor 프로젝트로부터 R 패키지를 이용하였다 (참조: 예를 들면, Li et al. 2009 Expert Rev Mol Diagn 9:555-566). 특히, 우리는 관찰된 변화의 통계학적 유의성을 판단하기 위해, limma (마이크로어레이 데이터에 대한 선형 모형)로부터 변형된 t 검정을 이용하였다 (참조: 예를 들면, Li et al. 2009 Expert Rev Mol Diagn 9:555-566).
yi 및 xi는 각각, 암 혈장 단백질체 및 정상적인 혈장 단백질체에서 i번째 단백질의 존재비를 표시하고, 따라서
yi ~ 정상(μyi, σyi)
그리고
xi ~ 정상(μxi, σxi)이고
여기서 μ와 σ는 3개의 데이터세트에서 펩티드 존재비의 평균과 분산을 표시한다. 복제물 사이에 유의미한 분산을 갖는 펩티드 생물마커 (정상과 비교하여 암 혈장 단백질체에서 고도로 상향조절됨)를 확인하는 것을 방지하기 위해, 우리는 t 검정을 채택하였는데, 여기서
상기 t 검정은 경험적 베이즈 방법에 의해 변형되었다. 모든 다른 것들로부터 별개로 각 펩티드를 검사하는 대신에, 경험적 베이즈 변형된 t 검정은 모든 다른 펩티드로부터 강도를 차용하고, 따라서 각 개별 펩티드의 오차 추정을 향상시킨다. limma R 패키지로부터 eBayes 변형된 t 검정이 표본 사이에 펩티드 존재비의 차이에 대한 통계학적 분석을 수행하는데 이용되었다. 전체적으로, 87개의 상이한 단백질로부터 208개의 펩티드가 후보 암 생물마커로서 확인되고 본 연구의 검증 단계로 이월되었다.
정량적 혈장 단백질체학에 의해 확인된 후보 생물마커. 단백질체학 데이터베이스 검색 (PRIDE, www.ebi.ac.uk/ pride/archive/, 그리고 Peptide Atlas, www.peptideatlas.org/ 이용)이 87개의 단백질에 대해 수행되었고, 그리고 이들의 가장 쉽게 검출가능한 253개 펩티드 (전술된 208개 이외에)가 후보 펩티드 목록에 추가되었다. 3개의 발견 데이터세트로부터 반복해서 관찰되지만 eBayes 변형된 t 검정을 통과하지 못한 다른 180개 펩티드 역시 추가되었다. 전체적으로, 641개의 후보 펩티드가 추가 검증에 종속되었다 (데이터세트 S4).
SAFE-SRM 검정의 개발. 우리의 연구에서 641개의 표적 펩티드를 표적으로 하는 총 4,384개의 트랜지션이 합성 펩티드를 이용함으로써 최적화되었다. 각 합성 펩티드에 대해, 부응하는 한 세트의 최적화된 충돌 에너지와 체류 시간이 획득되었다 (데이터세트 S5).
간단히 말하면, 약한 염기성 환경 (pH 8.2)에서 각 펩티드의 소수성에 근거하여 641개의 합성 펩티드를 96개의 분획물로 분리하기 위해 HPLC 분별이 수행되었다. 총 96개의 펩티드 분획물이 이후, 도 5에서 도시된 계획에 따라서, 각각 3개의 순차적 분획물을 포함하는 32개의 군으로 조직화되었다. 이들 군 각각은 Agilent 6490 삼중 4극 질량분광계에 연계된 C18-기초된 HPLC를 통한 분별에 종속되었다. 각 펩티드를 검출하기 위한 최적 파라미터를 결정하기 위해, 4,384개의 트랜지션 모두를 커버하는 SRM 검정이 이들 군 각각에서 수행되었다. 각 펩티드에 대한 SAFE-SRM 분획물 군 ID을 확인한 후, 각 분획물 군에 대한 고유한 SAFE-SRM 방법이 구축되었고, 그리고 표적 군 직전에 또는 직후에 용리되는 순차적 군에서 SRM 트랜지션 또한 상기 방법 내로 통합되었다 (도 5). 각 펩티드에 대한 SAFE-SRM 군 ID는 데이터세트 S5에서 열거되는데, 여기서 각 ID는 도 5에서 도시된 bRPLC 분별 플레이트를 지칭한다.
641개의 후보 펩티드가 합성되고, 그리고 3-단계 최적화 접근법을 이용하여 SAFE-SRM 방법을 확립하기 위한 표준으로서 이용되었다:
i) 선구 이온 (통상적으로 양으로 하전된 프로테오타이픽 펩티드) 및 생성 이온 (충돌-유도된 해리로부터 산출된 펩티드 단편)의 각 쌍에 대한 충돌 에너지의 최적화가 수행되었다. 각 선구 이온에 대해, 충돌 에너지의 이론적 최적 값보다 위쪽으로 2 단계 및 아래쪽으로 2 단계 (단계 크기, 4 eV)가 각 선구 이온을 단편화하는데 적용되었다. 각 펩티드에 대해, 가장 강한 강도를 보여주는 5 내지 8개의 단편화된 이온이 검출 표적으로서 선별되었다. 따라서 펩티드의 질량 대 전하 비율 (m/z), 최적화된 충돌 에너지 값, 그리고 펩티드 단편화된 이온의 m/z가 각 펩티드에 대해 확립되었다. 이런 값의 한 세트는 전형적으로, SRM 트랜지션으로 명명된다. 전체적으로, 641개의 펩티드를 표적으로 하기 위해 4,384개의 SRM 트랜지션이 이러한 방식으로 최적화되었다 (평균적으로, 펩티드마다 대략 7개의 트랜지션).
ii) bRPLC 분별의 최적화. 641개의 합성 펩티드가 앞서 설명된 바와 같이 준비된 연구의 1 단계에서 이용된 한데 모아진 정상적인 혈장 표본으로부터 유래된 펩티드 내로 스파이킹되었고, 그리고 3번의 독립된 HPLC 분별이 실행되었다. 상기에서 지적된 바와 같이, bRPLC 분별로부터 96개의 분획물이 "분획물 군" 내로 조합되었는데, 각 군은 3개의 순차적 분획물을 내포한다. 4,384개의 트랜지션이 각 트랜지션에 대한 고정된 체류 시간 (5 ms)에서, 각 bRPLC 분획물 군에서 사정되었다. 가장 많은 양의 각 펩티드를 내포하는 bRPLC 분획물 군이 결정되고, 따라서 각 펩티드에 대한 분획물 군 ID가 규정되었다. 각 펩티드에 대한 표준 강도 (SI) (10 fmol의 펩티드에 대해 질량분광계에 의해 계측된 강도) 역시 기록되었다.
iii) SRM 방법 어셈블리. 동일한 분획물 군 ID를 갖는 펩티드로부터 모든 트랜지션을 집성함으로써, 각 분획물 군에 대한 고유한 SRM 방법이 창출되었다. 동일한 SRM 트랜지션이 주요 분획물 군 전후에 용리하는 분획물 군에서 평가되었다. 따라서, 각 분획물 군은 SRM 트랜지션의 3개의 상이한 세트로 사정되었다. 각 트랜지션에 대한 체류 시간은 3 내지 20 ms의 범위에서 변하는, 상기 펩티드의 SI에 역비례하도록 변경되었다.
각 합성 펩티드에 대해, 부응하는 한 세트의 최적화된 충돌 에너지와 체류 시간이 획득되었다. 모든 펩티드에 대한 SRM 트랜지션 및 분획물 군 IDs의 목록은 데이터세트 S5에서 도시된다. 모든 트랜지션 파라미터는 수동으로 조사되고, 그리고 인간 혈장 표본에서 비특이적 피분석물과의 공동용리에 기인한 과도한 잡음을 갖는 이온이 배제되도록 관장되었다. 318개의 펩티드에 상응하는 1,990개 트랜지션의 한 세트가 1 단계에서 이용된 모든 진행암 혈장 표본의 풀에서 재현적으로 검출가능하였다 (데이터세트 S5).
표준 펩티드를 이용한 초기 방법-구축 단계 후, 우리는 최종 HPLC-MS 단계에서 분석되어야 하는 군의 숫자를 32개에서 20개로 감축할 수 있었다. 641개 펩티드 중에서 총 318개가 이들 20개 군 중에서 적어도 한 가지에서 재현적으로 관찰되었고, 1,990개의 검출가능한 트랜지션 (펩티드마다 평균 6.3개의 트랜지션)이 산출되었다.
SAFE-SRM의 성과 평가. 6개의 중동위원소-표지화된 펩티드 (펩티드 1: IQLVEEELDR* (서열 번호:3); 펩티드 2: VILHLK* (서열 번호:4); 펩티드 3: IILLFDAHK* (서열 번호:5); 펩티드 4: TLAESALQLLYTAK* (서열 번호:6); 펩티드 5: LLGHLVK* (서열 번호:7); 펩티드 6: GLVGEIIK* (서열 번호:8), 여기서 *는 C13과 N15 중동위원소-표지화된 아미노산을 지시한다)가 각각 1 fmol에서 혼합되었고, 그리고 혼합물은 표준 SRM 방법에 의해 분석되었다. 동등한 양 (각각 1 fmol)의 이들 6개 중동위원소-표지화된 펩티드가 단백질분해적으로 소화된 혈장 펩티드 표본 내로 스파이킹되고, 그 이후에 표준 SRM 접근법 (bRPLC 분별 없음), bRPLC-SRM 접근법, 또는 SAFE-SRM 접근법을 통해 검출되었다. 펩티드 존재비는 각 접근법에서 검출된 펩티드의 SRM 신호의 AUC에 의해 계산되었다.
Agilent 6490 질량분광계 조정. 제조업체의 조정 혼합물 (Autotune 및 Checktune)뿐만 아니라 우리가 제조한 조정 혼합물로 상기 기구의 성과의 확증 이후에만, 각 혈장 표본에 대한 SAFE-SRM 검정이 수행되었다. 우리의 조정 혼합물은 넓은 범위의 질량 (M/z 범위, 200-1,400) 및 소수성 (표 S2)을 나타내는 20개의 펩티드로 구성되었다.
표 S2. 조정 혼합물에서 표준 펩티드(각각 10 펨토 몰).
데이터 분석. 모든 군에 대해 20가지의 상이한 SRM 방법으로 구성되는 한 세트의 검정이 318개 펩티드 각각의 존재비를 정량하기 위해 수행되었다. 20개의 데이터세트가 각 혈장 표본에 대한 20가지 SAFE-SRM 방법을 이용하여 질량분광계에 의해 산출되고, 그리고 데이터 분석을 위해 Skyline 3.6 내로 이입되었다 (참조: 예를 들면, MacLean et al. 2010 Bioinformatics 26:966-968). 우리는 표본 준비 효율의 분산 및 질량분광계 민감도의 변동에 맞추어 조정하는 이중-대조 접근법을 통해, 표지화된 참조 펩티드 (LRP) 방법 (참조: 예를 들면, Zhang et al. 2011 Mol Cell Proteomics 10:M110.006593)을 향상시켰다. 첫 번째 대조는 표본 준비 전 혈장 표본 내로 스파이킹된 중동위원소-표지화된 돌연변이체 KRAS 단백질이었다. 두 번째 대조는 최종 HPLC-MS에서 실행하기 전, 각 군 내로 스파이킹된 중동위원소-표지화된 WT KRAS 펩티드이었다. 표적 펩티드의 존재비는 3-fmol 중동위원소 (무거운-리신 잔기)-표지화된 K-Ras WT 펩티드 (LVVVGAGGVGK; 서열 번호:23)로부터 모든 트랜지션의 총 AUC에 대해 정규화된 모든 이의 트랜지션의 곡선 아래 총면적 (AUC)에 의해 표시되었다. 표본 준비에서 변이는 소정의 표본으로부터 각 펩티드의 존재비를, Origene으로부터 구입된 중동위원소-표지화된 K-Ras 돌연변이체 (G12D) 단백질로부터 유래된 펩티드의 존재비에 정규화함으로써 조정되었다. 우리는 이러한 조정을 위해, 이러한 중동위원소 아미노산 (무거운-리신 및 무거운-아르기닌)-표지화된 단백질로부터 유래된 6개의 펩티드를 선별하였다. 펩티드 서열 및 최적화된 트랜지션 파라미터는 데이터세트 S5에서 열거된다.
모든 표본에서 318개 펩티드 각각에 대한 SAFE-SRM 존재비 점수 (S)가 계산되었다. Pi,j,k는 표본 j 분획물 k에서 펩티드 i의 적분 강도이고, Nj,k는 표본 j, 분획물 k에서 K-Ras WT 무거운 대조 펩티드의 적분 강도이고, 그리고 Mj는 표본 j에서 중앙값 존재비 K-RAS 단백질 펩티드의 적분 강도라고 가정한다. Si,j는 표본 j에서 펩티드 i의 존재비 점수이다; 이런 이유로, Si,j는 하기와 같이 계산될 수 있고:
여기서 Mj의 경우에:
본 연구에서, 318개 펩티드 중에서 71개가 2개의 인접한 SAFE-SRM 군의 전역에서 반복해서 검출되었다. 각 표본에서 이런 펩티드의 존재비는 이들 펩티드가 검출된 인접한 SAFE-SRM 실행에서 정규화된 존재비 점수를 가산함으로써 계산되었다.
SAFE-SRM 파이프라인의 재현성은 하기와 같이, 표본 j에 대한 재현성 비율 (RR)을 계산함으로써 계측되었다:
SAFE-SRM 파이프라인을 통해 처리된 각 표본에 대한 RR 값은 데이터세트 S7에서 열거되었다.
암 프로테오믹 생물마커 확인. 최고 펩티드 분류기를 확인하기 위해, 단계별 정방향 선별 로지스틱 회귀가 MATLAB 에서 이용되었다. 첫 번째, 로지스틱 회귀 모형은 318개의 펩티드 존재비 점수를 이용하여, 27개의 공지된 건강한 표본, 그리고 7개, 7개 및 9개의 공지된 결장직장암, 난소암 및 췌장암 혈장 표본을 포함하는 50개 표본의 훈련 세트에 적합되었다. 단일 잔류 교차 검증이 각 모형의 예측 성과를 추정하는데 이용되었다. 훈련 세트에서 가장 낮은 교차 검증된 오분류 비율을 산출하는 펩티드가 이러한 모형에 포함을 위해 선택되었다. 만약 하나 이상의 펩티드가 가장 낮은 오분류 비율을 달성하면, 최대 모형 가능성을 산출하는 펩티드를 선별함으로써 유대관계를 깨뜨렸다. 모형에 추가되는 펩티드 생물마커를 선별하는 이러한 과정은 교차 검증된 오분류 비율에서 추가 감소가 펩티드의 추가에 의해 더 이상 달성될 수 없을 때까지 반복되었다. 완벽한 분류를 달성할 수 있는, 동일한 단백질로부터 펩티드의 부분집합을 발견하기 위해, 각 잠재적인 생물마커 단백질에 대해 동일한 단계별 정방향 선별 절차가 적용되었다. 최고 분류기를 확인한 후, 펩티드 생물마커의 상이한 조합에 모형 적합의 예측 성과가 추가 48개의 표본에서 맹검 방식으로 비교되었다. 최고 펩티드 분류기의 조합에 의해, 그리고 각 개별 최고 펩티드 분류기에 의해 구축된 예측 모형이 73개 표본의 추가 코호트에서 맹검 방식으로 평가되었다.
결과
연구 설계. 본 연구는 정성적 및 정량적 MS 기술의 조합을 이용하여 암에 대한 고유한 프로테오믹 생물마커를 확인하고 검증하도록 설계되었다. 이 분야에서 대부분의 이전 연구는 암 조직의 분석으로 시작되고, 그리고 이후, 암-특이적 단백질 또는 펩티드가 혈장에서 확인될 수 있는 지를 결정하려 시도하였다. 본 연구에서, 우리는 혈장으로부터 직접적으로 후보 펩티드를 확인하려 시도하였다. 본 연구는 3가지 구별된 단계에서 실행되었다: 1 단계, 188개의 유전자로부터 641개의 후보 펩티드 마커를 산출하는, 암 환자 및 건강한 개체로부터 표본의 전역 혈장 프로테오믹 프로파일링; 2 단계, 펩티딜-프로릴 시스-트랜스 이성화효소 A (PPIA)로부터 2개의 펩티드를 유망한 생물마커로서 산출하는, 추가 혈장 표본에서 641개의 후보 펩티드 마커 각각을 평가하기 위한, SRM (SAFE-SRM)에 의한 분획된 용출물의 순차적 분석으로 불리는, 선별된 반응 모니터링 (SRM)-기초된 검정의 실행; 그리고 3 단계, SAFE-SRM을 이용하여 암 환자 및 대조의 독립된 세트에서 이들 2개 펩티드의 성과의 평가. 1 단계는 다수의 단백질의 정성 분석에 가장 적합한 Orbitrap 질량분광계에서 수행되었고, 반면 2와 3 단계는 선별된 피분석물의 정량 분석에 가장 적합한 삼중 4극 질량분광계에서 수행되었다. 상이한 공여자 공급원으로부터 총 266개의 혈장 표본이 본 연구의 이들 3가지 단계 동안 평가되었다 (표 S1).
표 S1. 연구에 관련된 연구 설계와 사례.
1 단계: 암 환자로부터 후보 생물마커의 확인. 암에 대한 잠재적인 단백질 생물마커를 확인하기 위해, 우리는 먼저, 50명의 정상적인 건강한 개체, 18명의 난소암 환자, 13명의 췌장암 환자, 그리고 18명의 결장직장암 환자로부터 동등한 체적의 혈장으로 구성되는 4개의 한데 모아진 인간 혈장 표본을 창출하였다 (데이터세트 S1). 모든 암 환자는 높은 농도의 추정 생물마커가 혈장에서 발견될 가능성을 최대화하기 위해 진행성 질환을 겪었다. 4개의 풀 각각으로부터 14가지의 매우 풍부한 단백질, 예컨대 알부민 및 면역글로불린을 제거하기 위한, 항체-기초된 혈장 고갈이 수행되었다. 각 풀은 이후, 트립신으로 소화되었고, 그리고 결과의 펩티드는 iTRAQ로 차별적으로 표지화되었다. iTRAQ 표지화는 이들 4개의 풀이 혼합되고 단일 MS 실험에서 분석될 수 있도록 한다. 이들 풀은 이후, 전체 단백질체를 사정하기 위해 분석되었다 (도 1A 및 도 4A). 별개의 실험에서, 글리코실화된 단백질로부터 유래된 펩티드에서 잠재적인 차이를 드러내기 위해, 한데 모아진 혈장 표본이 트립신 소화 및 iTRAQ 표지화 전에 당단백질에 대해 농축되었다 (도 4B).
우리는 도 4에서 개설된 전체 작업 흐름의 반복을 수행하였다. 전체적으로, 223,602개의 펩티드가 이들 분석을 통해 확인되었는데, 대표적으로 10,789개의 고유 펩티드가 1,249개의 고유 단백질로부터 확인되었다 (데이터세트 S2와 S3). 암 환자 및 정상적인 개체로부터 혈장 표본에서 이들 펩티드 각각의 상대적 존재비가 이후, 경험적-베이즈 변형된 t 검정 (재료와 방법)을 이용하여 계산되었다. 총 8,069개의 고유 펩티드가 적어도 2개의 복제물에서 정량되었고, 그리고 복제물 사이에 이들 펩티드의 존재비에 대한 상관은 0.74 (95% CI, 0.73-0.75)이었다. 재료와 방법에서 상세하게 설명된 바와 같이, 우리의 분석은 궁극적으로, 한데 모아진 정상적인 대조와 비교하여 한데 모아진 암 혈장 표본에서 유의미하게 증가된 존재비를 갖는 188개의 단백질로부터 유래된 641개의 펩티드를 산출하였다 (데이터세트 S4).
2a 단계: SAFE-SRM의 개발. 수백 개의 고유한 잠재적인 펩티드 생물마커의 검증은 쉽지 않은 과제이다. 이러한 어려움은 혈장 단백질로부터 이런 펩티드의 존재비가 일반적으로 낮고, 그리고 상이한 펩티드의 존재비가 이러한 낮은 범위 내에서 상당히 달라진다는 사실에 의해 악화된다. 우리는 이들 과제를 다루기 위한, 5가지 주요 성분을 갖는 접근법을 개발하였다. 첫 번째, 관심되는 641개의 펩티드가 개별적으로 합성되긴 하지만, 비용을 관리가능하게 유지하기 위해 고도로 정제되지는 않았다. 두 번째, 이들 펩티드 각각에 대한 SRM 방법이 창출되었다. 641가지 방법 각각은 주로 관심되는 충돌후 펩티드-특이적 트랜지션의 가장 높은 강도를 산출하는 선구 이온의 충돌 에너지와 체류 시간에 대해 최적화되었다. 각 펩티드에 제공된 체류 시간은 동등한 양의 합성 펩티드로 스파이킹된 인간 혈장 펩티드 표본으로부터 계측된 이러한 펩티드의 강도에 역비례하였다. 이러한 특질은 상기 기기가 더욱 낮은 신호 강도를 갖는 펩티드를 검출하는데 더욱 많은 시간을 소모하고, 따라서 낮은-존재비 펩티드의 검출에 대한 전체 이온 통계를 향상시키는 것을 가능하게 하였다. 이러한 프로토콜은 4,384개의 트랜지션(펩티드마다 대략 7개의 트랜지션; 데이터세트 S5)의 확인을 이끌어냈다.
세 번째, 이들 펩티드가 염기성 pH 역상 액체 크로마토그래피 (bRPLC)를 이용하여 분획되어, 3개의 순차적 분획물을 각각 내포하는 32개의 "분획물 군"으로 조직화되는 96개의 분획물이 산출되었다; 20개의 분획물 군이 추가 분석을 위해 선택되었다. 네 번째, 각 분획물 군에서 펩티드가 소수성 상호작용 (C18-RPLC)에 근거하여 직교 고성능 액체 크로마토그래피 (HPLC) 방법에 의해 분리되었다. 최종적으로, 전술된 합성 펩티드를 이용하여 미리 최적화된 충돌 에너지, 체류 시간 및 트랜지션으로 구성되는 SRM 방법을 이용하여, 두 번째 HPLC 칼럼으로부터 연속 용리액이 분석되었다. 우리는 이러한 접근법을 SAFE-SRM으로 명명하였다 (도 5). SAFE-SRM의 한 가지 이점은 이것이 2차원 크로마토그래피 분별을 이용한다는 점이다. 개별 분획물이 전체보다 훨씬 적은 펩티드를 내포하고, 따라서 원치 않는 펩티드로부터 이온 억제가 감소하고 신호 대 잡음 비율이 증가한다. SAFE-SRM의 두 번째 이점은 이것이 펩티드 발견에 이용되는 정성적 접근법을 검증 단계 동안 정량적 접근법으로 전환한다는 점이다. 최종적으로, 상기 방법은 순차적 분획물이 펩티드 존재비에 대해 중복 검사되기 때문에, bRPLC 크로마토그래피에서 통상적으로 관찰되는 용리 시간에서 변동에 고도로 내성이다 (재료와 방법).
SAFE-SRM의 성과를 사정하기 위해, 우리는 HPLC에서 상이한 소수성 특징을 갖는 6개의 펩티드를 선택하고 이들을 중동위원소-표지화된 형태로서 합성하였다 (재료와 방법). 우리는 이후, 이들 펩티드를 혼합하고, 그리고 전술된 최적화된 충돌 에너지와 체류 시간을 이용하여 표준 SRM 분석을 수행하였다. 6개 펩티드 모두 예상한 대로, 높은 신뢰도로 검출되었다. 하지만, 우리가 이들 펩티드를, 전술된 바와 같이 정상적인 혈장으로부터 산출된 트립신-소화된 표본 내로 스파이킹할 때, 이들의 평균 강도는 순수한 펩티드로 획득된 것의 단지 5% 정도에 불과하였고, 그리고 이들 6개 펩티드 중에서 단지 3개만 검출가능하였다. 이러한 스파이킹된 표본이 SAFE-SRM로 분석될 때에는 6개 펩티드 모두 평균적으로, 순수한 펩티드로 획득된 것의 70% 강도로 검출될 수 있었다 (도 2).
2b 단계: SAFE-SRM에 의한 후보 펩티드의 검사. 우리는 SAFE-SRM을 이용함으로써, 본 연구의 초기 iTRAQ-기초된 발견 단계에 이용된 4개의 혈장 풀을 평가하기 시작하였다. 우리는 이들 한데 모아진 표본에서 검출가능한 펩티드가 이온 억제, 동일한 크로마토그래피 분획물에서 원치 않는 펩티드의 공동용리, 또는 다른 기술적인 문제에 의해 영향을 받을 가능성이 거의 없는 것들일 것이라고 예상하였다. 세심한 검사 후, 641개의 검사된 펩티드 중에서 318개가 1,990개의 트랜지션 (펩티드마다 6.3개의 트랜지션; 데이터세트 S5)을 통해, 한데 모아진 표본에서 재현적으로 검출가능한 것으로 입증되었다. 이들 318개 펩티드는 121개의 단백질에 지도화되었다.
우리는 이후, SAFE-SRM을 이용하여, 발견 단계에서 이용되지 않은 94개의 개별 혈장 표본을 평가하였다. 이들 표본 중에서 48개가 정상적인 개체로부터 획득되었고, 그리고 14개, 14개 및 18개가 각각, 결장직장암 환자, 난소암 환자 및 췌장암 환자로부터 획득되었다 (데이터세트 S1). 94개의 개별 및 4개의 한데 모아진 혈장 표본 각각에서 318개의 펩티드 각각에 대한 SAFE-SRM 존재비 점수가 계산되었다 (데이터세트 S6). 우리는 임의의 펩티드 또는 펩티드의 조합이 펩티드 시그너처로부터 표본의 기원을 정확하게 분류할 수 있는 지를 결정하기 위해 통계학적 방법을 이용하였다. 이런 목적으로, 우리는 훈련을 위한 표본 중에서 대략 절반 (건강한 공여자로부터 27개, 그리고 결장직장암 환자, 난소암 환자, 또는 췌장암 환자 각각으로부터 7개, 7개 및 9개의 표본)을 무작위로 선별하였다. 표본의 나머지 절반은 훈련 표본으로부터 유래된 분류기의 성과를 검사하는데 이용되었다.
분류 모형이 진전됨에 따라서 이의 예측 성과를 추정하기 위해, 반복적인 단일 잔류 교차 검증 전략이 이용되었다. 훈련 세트에서 가장 높은 교차 검증된 분류 점수를 산출하는 펩티드가 먼저 선별되었다. 이후, 임의의 두 번째 펩티드가 분류 점수를 증가시킬 수 있는 지를 결정하기 위해, 이들 펩티드에 관한 데이터가 검색되었다. 추가되는 펩티드 생물마커를 선별하는 이러한 과정은 분류 점수에서 추가 증가가 다른 펩티드의 추가에 의해 더 이상 달성될 수 없을 때까지 반복되었다. 이러한 접근법을 이용하여, 탁월한 분류 잠재력을 갖는 펩티드의 여러 조합이 확인되었다 (도 3A와 B).
여러 마커의 조합으로 난소암의 분류에 대한 최고 성과가 관찰되었다. 난소암에 대한 상위 단일 펩티드 마커는 PPIA (시클로필린-A로서 또한 알려져 있음)로부터 VSFELFADK (서열 번호:1)이었다. 우리는 이후, 318-펩티드 세트에서 것들 중에서 PPIA로부터 임의의 다른 펩티드가 특이성을 감소시키지 않으면서 분류기에 추가될 수 있는 지를 결정하였고, 그리고 PP1A로부터 두 번째 펩티드 (FEDENFILK; 서열 번호:2)가 이러한 방식으로 추가될 수 있다는 것을 발견하였다 (도 3C). 36개의 정상적인 표본 사이에서 100% 특이성을 유발하는 펩티드 존재비 수준을 이용하여, 우리는 VSFELFADK (서열 번호:1) 및 FEDENFILK (서열 번호:2)가 각각, 75.0%와 78.6% 민감도를 산출한다는 것을 발견하였다. 이들 2개의 PPIA 펩티드에 대한 피어슨 상관 계수는 0.83 (95% CI, 0.78-0.87)이었다. 이들 2개의 펩티드 중에서 적어도 하나는 28개 표본 중에서 23개 (82.1%)에서 상승되었다.
3 단계: 검증. 분류기를 형성하는데 이용된 데이터세트는 컸다: 98개의 표본 각각에서 검사된 318개의 펩티드로부터 1,990개의 트랜지션. 이런 실험에서 과다적합이 가능하고, 그리고 임의의 분류기의 독립된 검증이 의무적인 것으로 널리 알려져 있다. 우리는 이런 이유로, 35가지 난소암 사례로부터 혈장 및 건강한 개체 또는 다른 암 유형의 환자로부터 38개의 표본으로 구성되는 73가지 사례의 별개의 코호트를 평가하였다 (데이터세트 S7). 이들 73가지 사례에서, SAFE-SRM이 수행되긴 했지만, 분석된 유일한 트랜지션은 PPIA로부터 2개의 펩티드 플러스 섬유결합소로부터 펩티드에 상응하는 것들이었는데, 이들은 모든 표본에서 유사한 수준으로 발현되는 것으로 밝혀졌고, 따라서 정규화에 이용되었다. 양성 점수를 위해 필요한 상대적 존재비는 전술된 2b 단계에서 결과로부터 미리 결정되었다. 난소암 환자 및 정상적인 개체에서 이들 펩티드에 대한 SAFE-SRM 프로필의 실례는 도 6에서 도시된다. 난소암 사례로부터 35개의 혈장 표본 중에서 20개 (57.1%; 95% CI, 40-73%)가 PPIA로부터 VSFELFADK (서열 번호:1)에 대해 양성으로 채점되었고, 반면 정상적인 개체로부터 14개의 표본 중에서 어느 것도 양성으로 채점되지 않았다 (100%의 특이성; 95% CI, 89-100%). PPIA로부터 두 번째 펩티드 FEDENFILK (서열 번호:2)의 경우에, 난소암 사례로부터 35개의 혈장 표본 중에서 14개 (40.0%; 95% CI, 24-58%)가 양성으로 채점되었고, 그리고 첫 번째 PPIA 펩티드에서처럼, 건강한 개체로부터 14개의 표본 중에서 어느 것도 양성으로 채점되지 않았다. FEDENFILK (서열 번호:2) 펩티드에 대해 양성으로 채점되는 모든 혈장 표본은 동일한 단백질로부터 VSFELFADK (서열 번호:1)에 대해서도 양성으로 채점되었다. 24명의 췌장암 환자가 이러한 검정에서 검사되었고, 그리고 이들 중에서 단지 1명 (4.2%; 95% CI, 0.2-23.1%)만 펩티드 VSFELFADK (서열 번호:1)에 대해 양성으로 채점되었고 펩티드 FEDENFILK (서열 번호:2)에 대해서는 양성으로 채점된 환자가 없었다 (데이터세트 S7).
초기 단계 난소암을 겪는 환자로부터 17개의 혈장 중에서 11개 (64.7%)가 PPIA 펩티드에 대해 양성으로 채점된 반면, 더욱 진행된 암을 겪는 환자로부터 46개의 혈장 중에서 32개 (69.6%)가 양성으로 채점된다는 것은 유의할 만하였다(2b 단계 및 3 단계 조합; 데이터세트 S7). 비교를 위해, CA125 수준이 동일한 코호트의 부분집합에서 계측되었다. CA125는 63명의 난소암 환자 중에서 20명에서 상승되었고, 그리고 50명의 건강한 대조에서는 상승되지 않았다. CA125 및 PPIA에서 상승은 완전히 겹치지는 않았고, 따라서 CA125 또는 PPIA 수준 중에서 어느 한 가지의 검출에 대한 민감도는 어느 한 쪽 단독보다 높은 74.6% (95% CI, 62.1-84.7%)이었다 (참조: 도 7에서 벤 다이어그램).
이들 결과는 SAFE-SRM이 순환하는 질환 특이적 펩티드를 발견하기 위한 일반화가능한 방법으로서 이용될 수 있다는 것을 증명한다. 구체적으로, SAFE-SRM 방법은 포유동물이 난소암을 겪는 것으로 확인하기 위한 순환하는 펩티드 마커로서 이용될 수 있는, PPIA로부터 펩티드를 확인하고 검증하는데 이용되었다.
다른 구체예
본 발명이 상세한 설명과 함께 설명되긴 했지만, 전술한 설명은 발명을 예시하고 발명의 범위를 한정하지 않는 것으로 의도되고, 상기 범위는 첨부된 청구항의 범위에 의해 규정되는 것으로 이해된다. 다른 양상, 이점 및 변형은 하기 청구항의 범위 내에 있다.
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SEQUENCE LISTING
<110> VOGELSTEIN, BERT
KINZLER, KENNETH W.
WANG, QING
PAPADOPOULOS, NICKOLAS
ZHANG, MING
<120> METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER
<130> 44807-0302WO1
<140> PCT/US2018/062007
<141> 2018-11-20
<150> 62/588,654
<151> 2017-11-20
<160> 6646
<170> PatentIn version 3.5
<210> 1
<211> 9
<212> PRT
<213> Unknown
<220>
<221> source
<223> /note="Description of Unknown:
PPIA peptide fragment"
<400> 1
Val Ser Phe Glu Leu Phe Ala Asp Lys
1 5
<210> 2
<211> 9
<212> PRT
<213> Unknown
<220>
<221> source
<223> /note="Description of Unknown:
PPIA peptide fragment"
<400> 2
Phe Glu Asp Glu Asn Phe Ile Leu Lys
1 5
<210> 3
<211> 10
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 3
Ile Gln Leu Val Glu Glu Glu Leu Asp Arg
1 5 10
<210> 4
<211> 6
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 4
Val Ile Leu His Leu Lys
1 5
<210> 5
<211> 9
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 5
Ile Ile Leu Leu Phe Asp Ala His Lys
1 5
<210> 6
<211> 14
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 6
Thr Leu Ala Glu Ser Ala Leu Gln Leu Leu Tyr Thr Ala Lys
1 5 10
<210> 7
<211> 7
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 7
Leu Leu Gly His Leu Val Lys
1 5
<210> 8
<211> 8
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 8
Gly Leu Val Gly Glu Ile Ile Lys
1 5
<210> 9
<211> 7
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 9
Asp Glu Ile Glu Ser Val Lys
1 5
<210> 10
<211> 10
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 10
Val Gly Ser Ala Lys Pro Gly Leu Gln Lys
1 5 10
<210> 11
<211> 6
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 11
Glu Thr Ile Val Leu Lys
1 5
<210> 12
<211> 8
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 12
Ser Ile Val Asn Tyr Lys Pro Lys
1 5
<210> 13
<211> 11
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 13
Asp Leu Gln Phe Val Glu Val Thr Asp Val Lys
1 5 10
<210> 14
<211> 13
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 14
Thr Leu Leu Gly Asp Gly Pro Val Val Thr Asp Pro Lys
1 5 10
<210> 15
<211> 11
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 15
His Phe Thr Ile Leu Asp Ala Pro Gly His Lys
1 5 10
<210> 16
<211> 10
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 16
Leu Val Asp Lys Phe Leu Glu Asp Val Lys
1 5 10
<210> 17
<211> 7
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 17
Lys Ile Pro Val Val Phe Arg
1 5
<210> 18
<211> 8
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 18
Phe Pro Val Ile Gln His Phe Lys
1 5
<210> 19
<211> 9
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 19
Phe Phe Leu Ser His Pro Ala Tyr Arg
1 5
<210> 20
<211> 9
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 20
Leu Phe Ala Gly Leu Val His Val Lys
1 5
<210> 21
<211> 16
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 21
Val Leu Asp Phe Glu His Phe Leu Pro Met Leu Gln Thr Val Ala Lys
1 5 10 15
<210> 22
<211> 16
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<400> 22
Leu Leu Gly Asn Val Leu Val Cys Val Leu Ala His His Phe Gly Lys
1 5 10 15
<210> 23
<211> 11
<212> PRT
<213> Unknown
<220>
<221> source
<223> /note="Description of Unknown:
K-Ras wild-type (WT) peptide"
<400> 23
Leu Val Val Val Gly Ala Gly Gly Val Gly Lys
1 5 10
<210> 24
<211> 12
<212> PRT
<213> Homo sapiens
<400> 24
Ala Ala Ala Ala Thr Gly Thr Ile Phe Thr Phe Arg
1 5 10
<210> 25
<211> 7
<212> PRT
<213> Homo sapiens
<400> 25
Ala Ala Ala Leu Leu Pro Lys
1 5
<210> 26
<211> 7
<212> PRT
<213> Homo sapiens
<400> 26
Ala Ala Ala Asn Gln Met Arg
1 5
<210> 27
<211> 8
<212> PRT
<213> Homo sapiens
<400> 27
Ala Ala Ala Pro Asn Thr Pro Lys
1 5
<210> 28
<211> 7
<212> PRT
<213> Homo sapiens
<400> 28
Ala Ala Cys Leu Leu Pro Lys
1 5
<210> 29
<211> 13
<212> PRT
<213> Homo sapiens
<400> 29
Ala Ala Asp Asp Thr Trp Glu Pro Phe Ala Ser Gly Lys
1 5 10
<210> 30
<211> 17
<212> PRT
<213> Homo sapiens
<400> 30
Ala Ala Asp Ile Glu Gln Gln Ala Val Phe Ala Val Phe Asp Glu Asn
1 5 10 15
Lys
<210> 31
<211> 28
<212> PRT
<213> Homo sapiens
<400> 31
Ala Ala Glu Ala Ala Ala Ala Pro Ala Glu Ser Ala Ala Pro Ala Ala
1 5 10 15
Gly Glu Glu Pro Ser Lys Glu Glu Gly Glu Pro Lys
20 25
<210> 32
<211> 8
<212> PRT
<213> Homo sapiens
<400> 32
Ala Ala Phe Asp Gln Arg Met Lys
1 5
<210> 33
<211> 7
<212> PRT
<213> Homo sapiens
<400> 33
Ala Ala Phe Asn Ser Gly Lys
1 5
<210> 34
<211> 16
<212> PRT
<213> Homo sapiens
<400> 34
Ala Ala Gly Asn Glu Cys Pro Glu Leu Gln Pro Pro Val His Gly Lys
1 5 10 15
<210> 35
<211> 5
<212> PRT
<213> Homo sapiens
<400> 35
Ala Ala Ile Asn Lys
1 5
<210> 36
<211> 7
<212> PRT
<213> Homo sapiens
<400> 36
Ala Ala Ile Gln Ala Leu Arg
1 5
<210> 37
<211> 8
<212> PRT
<213> Homo sapiens
<400> 37
Ala Ala Ile Gln Ala Leu Arg Lys
1 5
<210> 38
<211> 12
<212> PRT
<213> Homo sapiens
<400> 38
Ala Ala Ile Ser Gly Glu Asn Ala Gly Leu Val Arg
1 5 10
<210> 39
<211> 21
<212> PRT
<213> Homo sapiens
<400> 39
Ala Ala Leu Gly Lys Leu Pro Gln Gln Ala Asn Asp Tyr Leu Asn Ser
1 5 10 15
Phe Asn Trp Glu Arg
20
<210> 40
<211> 7
<212> PRT
<213> Homo sapiens
<400> 40
Ala Ala Leu Gln Ala Leu Arg
1 5
<210> 41
<211> 14
<212> PRT
<213> Homo sapiens
<400> 41
Ala Ala Leu Ser Gly Ala Asn Val Leu Thr Leu Ile Glu Lys
1 5 10
<210> 42
<211> 22
<212> PRT
<213> Homo sapiens
<400> 42
Ala Ala Leu Thr Glu Leu Ser Leu Gly Ser Ala Tyr Gln Ala Met Ile
1 5 10 15
Leu Gly Val Asp Ser Lys
20
<210> 43
<211> 10
<212> PRT
<213> Homo sapiens
<400> 43
Ala Ala Met Leu Ile Arg Pro Leu Lys Leu
1 5 10
<210> 44
<211> 14
<212> PRT
<213> Homo sapiens
<400> 44
Ala Ala Met Val Gly Met Leu Ala Asn Phe Leu Gly Phe Arg
1 5 10
<210> 45
<211> 10
<212> PRT
<213> Homo sapiens
<400> 45
Ala Ala Asn Phe Glu Asn His Ser Gly Lys
1 5 10
<210> 46
<211> 15
<212> PRT
<213> Homo sapiens
<400> 46
Ala Ala Asn Ser Leu Glu Ala Phe Ile Phe Glu Thr Gln Asp Lys
1 5 10 15
<210> 47
<211> 16
<212> PRT
<213> Homo sapiens
<400> 47
Ala Ala Pro Gly Gln Glu Pro Pro Glu His Met Ala Glu Leu Gln Arg
1 5 10 15
<210> 48
<211> 9
<212> PRT
<213> Homo sapiens
<400> 48
Ala Ala Pro Gly Tyr His Met Ala Lys
1 5
<210> 49
<211> 8
<212> PRT
<213> Homo sapiens
<400> 49
Ala Ala Gln Glu Glu Tyr Val Lys
1 5
<210> 50
<211> 15
<212> PRT
<213> Homo sapiens
<400> 50
Ala Ala Gln Val Thr Ile Gln Ser Ser Gly Thr Phe Ser Ser Lys
1 5 10 15
<210> 51
<211> 23
<212> PRT
<213> Homo sapiens
<400> 51
Ala Ala Gln Val Thr Ile Gln Ser Ser Gly Thr Phe Ser Ser Lys Phe
1 5 10 15
Gln Val Asp Asn Asn Asn Arg
20
<210> 52
<211> 7
<212> PRT
<213> Homo sapiens
<400> 52
Ala Ala Arg Ala Leu Gln Lys
1 5
<210> 53
<211> 8
<212> PRT
<213> Homo sapiens
<400> 53
Ala Ala Arg Val Ile Ile Glu Lys
1 5
<210> 54
<211> 11
<212> PRT
<213> Homo sapiens
<400> 54
Ala Ala Ser Gly Thr Gln Asn Asn Val Leu Arg
1 5 10
<210> 55
<211> 13
<212> PRT
<213> Homo sapiens
<400> 55
Ala Ala Ser Gly Thr Thr Gly Thr Tyr Gln Glu Trp Lys
1 5 10
<210> 56
<211> 15
<212> PRT
<213> Homo sapiens
<400> 56
Ala Ala Ser Gly Thr Thr Gly Thr Tyr Gln Glu Trp Lys Asp Lys
1 5 10 15
<210> 57
<211> 12
<212> PRT
<213> Homo sapiens
<400> 57
Ala Ala Thr Gly Glu Cys Thr Ala Thr Val Gly Lys
1 5 10
<210> 58
<211> 13
<212> PRT
<213> Homo sapiens
<400> 58
Ala Ala Thr Gly Glu Cys Thr Ala Thr Val Gly Lys Arg
1 5 10
<210> 59
<211> 15
<212> PRT
<213> Homo sapiens
<400> 59
Ala Ala Thr Val Gly Ser Leu Ala Gly Gln Pro Leu Gln Glu Arg
1 5 10 15
<210> 60
<211> 8
<212> PRT
<213> Homo sapiens
<400> 60
Ala Ala Val His Leu Glu Gly Lys
1 5
<210> 61
<211> 13
<212> PRT
<213> Homo sapiens
<400> 61
Ala Ala Val Tyr His His Phe Ile Ser Asp Gly Val Arg
1 5 10
<210> 62
<211> 14
<212> PRT
<213> Homo sapiens
<400> 62
Ala Ala Val Tyr His His Phe Ile Ser Asp Gly Val Arg Lys
1 5 10
<210> 63
<211> 34
<212> PRT
<213> Homo sapiens
<400> 63
Ala Ala Val Tyr Gln Pro Gln Pro His Pro Gln Pro Pro Pro Tyr Gly
1 5 10 15
His Cys Val Thr Asp Ser Gly Val Val Tyr Ser Val Gly Met Gln Trp
20 25 30
Leu Lys
<210> 64
<211> 5
<212> PRT
<213> Homo sapiens
<400> 64
Ala Ala Trp Gly Lys
1 5
<210> 65
<211> 28
<212> PRT
<213> Homo sapiens
<400> 65
Ala Cys Pro Ser His Gln Pro Asp Ile Ser Ser Gly Leu Glu Leu Pro
1 5 10 15
Phe Pro Pro Gly Val Pro Thr Leu Asp Asn Ile Lys
20 25
<210> 66
<211> 14
<212> PRT
<213> Homo sapiens
<400> 66
Ala Asp Ala Glu Gly Glu Ser Asp Leu Glu Asn Ser Arg Lys
1 5 10
<210> 67
<211> 12
<212> PRT
<213> Homo sapiens
<400> 67
Ala Asp Asp Gly Arg Pro Phe Pro Gln Val Ile Lys
1 5 10
<210> 68
<211> 16
<212> PRT
<213> Homo sapiens
<400> 68
Ala Asp Gly Glu Ser Cys Ser Ala Ser Met Met Tyr Gln Glu Gly Lys
1 5 10 15
<210> 69
<211> 12
<212> PRT
<213> Homo sapiens
<400> 69
Ala Asp Gly Leu Ala Val Ile Gly Val Leu Met Lys
1 5 10
<210> 70
<211> 17
<212> PRT
<213> Homo sapiens
<400> 70
Ala Asp Gly Ser Pro Val Lys Ala Gly Val Glu Thr Thr Lys Pro Ser
1 5 10 15
Lys
<210> 71
<211> 11
<212> PRT
<213> Homo sapiens
<400> 71
Ala Asp Gly Ser Tyr Ala Ala Trp Leu Ser Arg
1 5 10
<210> 72
<211> 11
<212> PRT
<213> Homo sapiens
<400> 72
Ala Asp His Asp Ala Leu Leu Phe His Leu Lys
1 5 10
<210> 73
<211> 15
<212> PRT
<213> Homo sapiens
<400> 73
Ala Asp His His Ala Thr Asn Gly Val Val His Leu Ile Asp Lys
1 5 10 15
<210> 74
<211> 5
<212> PRT
<213> Homo sapiens
<400> 74
Ala Asp Ile Glu Lys
1 5
<210> 75
<211> 5
<212> PRT
<213> Homo sapiens
<400> 75
Ala Asp Ile Thr Lys
1 5
<210> 76
<211> 13
<212> PRT
<213> Homo sapiens
<400> 76
Ala Asp Lys Pro Leu Ser Ile His Pro Gln Gly Ile Arg
1 5 10
<210> 77
<211> 5
<212> PRT
<213> Homo sapiens
<400> 77
Ala Asp Leu Glu Lys
1 5
<210> 78
<211> 12
<212> PRT
<213> Homo sapiens
<400> 78
Ala Asp Leu Glu Lys Leu Thr Ser Leu Ser Asp Arg
1 5 10
<210> 79
<211> 18
<212> PRT
<213> Homo sapiens
<400> 79
Ala Asp Leu Glu Met Gln Ile Glu Ser Leu Thr Glu Glu Leu Ala Tyr
1 5 10 15
Leu Lys
<210> 80
<211> 16
<212> PRT
<213> Homo sapiens
<400> 80
Ala Asp Leu Phe Tyr Asp Val Glu Ala Leu Asp Leu Glu Ser Pro Lys
1 5 10 15
<210> 81
<211> 21
<212> PRT
<213> Homo sapiens
<400> 81
Ala Asp Leu Leu Leu Ser Thr Gln Pro Gly Arg Glu Glu Gly Ser Pro
1 5 10 15
Leu Glu Leu Glu Arg
20
<210> 82
<211> 10
<212> PRT
<213> Homo sapiens
<400> 82
Ala Asp Leu Ser Gly Ile Thr Gly Ala Arg
1 5 10
<210> 83
<211> 20
<212> PRT
<213> Homo sapiens
<400> 83
Ala Asp Leu Ser Gly Ile Thr Gly Ala Arg Asn Leu Ala Val Ser Gln
1 5 10 15
Val Val His Lys
20
<210> 84
<211> 36
<212> PRT
<213> Homo sapiens
<400> 84
Ala Asp Asn Phe Leu Leu Glu Asn Thr Leu Pro Ala Gln Ser Thr Phe
1 5 10 15
Thr Leu Ala Ile Ser Ala Tyr Ala Leu Ser Leu Gly Asp Lys Thr His
20 25 30
Pro Gln Phe Arg
35
<210> 85
<211> 6
<212> PRT
<213> Homo sapiens
<400> 85
Ala Asp Pro Phe Leu Arg
1 5
<210> 86
<211> 15
<212> PRT
<213> Homo sapiens
<400> 86
Ala Asp Arg Asp Gln Tyr Glu Leu Leu Cys Leu Asp Asn Thr Arg
1 5 10 15
<210> 87
<211> 24
<212> PRT
<213> Homo sapiens
<400> 87
Ala Asp Ser Gln Ala Gln Leu Leu Leu Ser Thr Val Val Gly Val Phe
1 5 10 15
Thr Ala Pro Gly Leu His Leu Lys
20
<210> 88
<211> 41
<212> PRT
<213> Homo sapiens
<400> 88
Ala Asp Ser Gln Ala Gln Leu Leu Leu Ser Thr Val Val Gly Val Phe
1 5 10 15
Thr Ala Pro Gly Leu His Leu Lys Gln Pro Phe Val Gln Gly Leu Ala
20 25 30
Leu Tyr Thr Pro Val Val Leu Pro Arg
35 40
<210> 89
<211> 23
<212> PRT
<213> Homo sapiens
<400> 89
Ala Asp Ser Val Val Asp Leu Leu Ser Tyr Asn Val Gln Gly Ser Gly
1 5 10 15
Glu Thr Thr Tyr Asp His Lys
20
<210> 90
<211> 15
<212> PRT
<213> Homo sapiens
<400> 90
Ala Asp Thr Ala Lys Glu Val Ser Phe Asp Val Glu Leu Pro Lys
1 5 10 15
<210> 91
<211> 32
<212> PRT
<213> Homo sapiens
<400> 91
Ala Asp Thr His Asp Glu Ile Leu Glu Gly Leu Asn Phe Asn Leu Thr
1 5 10 15
Glu Ile Pro Glu Ala Gln Ile His Glu Gly Phe Gln Glu Leu Leu Arg
20 25 30
<210> 92
<211> 9
<212> PRT
<213> Homo sapiens
<400> 92
Ala Asp Thr Asn Gln Leu Ala Asp Lys
1 5
<210> 93
<211> 15
<212> PRT
<213> Homo sapiens
<400> 93
Ala Asp Val Leu Thr Thr Gly Ala Gly Asn Pro Val Gly Asp Lys
1 5 10 15
<210> 94
<211> 24
<212> PRT
<213> Homo sapiens
<400> 94
Ala Asp Val Gln Ala His Gly Glu Gly Gln Glu Phe Ser Ile Thr Cys
1 5 10 15
Leu Val Asp Glu Glu Glu Met Lys
20
<210> 95
<211> 25
<212> PRT
<213> Homo sapiens
<400> 95
Ala Asp Val Gln Ala His Gly Glu Gly Gln Glu Phe Ser Ile Thr Cys
1 5 10 15
Leu Val Asp Glu Glu Glu Met Lys Lys
20 25
<210> 96
<211> 5
<212> PRT
<213> Homo sapiens
<400> 96
Ala Asp Tyr Glu Lys
1 5
<210> 97
<211> 13
<212> PRT
<213> Homo sapiens
<400> 97
Ala Glu Ala Gln Ala Gln Tyr Ser Ala Ala Val Ala Lys
1 5 10
<210> 98
<211> 8
<212> PRT
<213> Homo sapiens
<400> 98
Ala Glu Ala Gln Val Glu Leu Arg
1 5
<210> 99
<211> 9
<212> PRT
<213> Homo sapiens
<400> 99
Ala Glu Ala Ser Gln Leu Gly His Lys
1 5
<210> 100
<211> 21
<212> PRT
<213> Homo sapiens
<400> 100
Ala Glu Ala Thr Thr Leu His Val Ala Pro Gln Gly Thr Ala Met Ala
1 5 10 15
Val Ser Thr Phe Arg
20
<210> 101
<211> 15
<212> PRT
<213> Homo sapiens
<400> 101
Ala Glu Asp His Phe Ser Val Ile Asp Phe Asn Gln Asn Ile Arg
1 5 10 15
<210> 102
<211> 7
<212> PRT
<213> Homo sapiens
<400> 102
Ala Glu Asp Leu Val Gly Lys
1 5
<210> 103
<211> 11
<212> PRT
<213> Homo sapiens
<400> 103
Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys
1 5 10
<210> 104
<211> 20
<212> PRT
<213> Homo sapiens
<400> 104
Ala Glu Glu Glu His Leu Gly Ile Leu Gly Pro Gln Leu His Ala Asp
1 5 10 15
Val Gly Asp Lys
20
<210> 105
<211> 22
<212> PRT
<213> Homo sapiens
<400> 105
Ala Glu Glu Glu His Leu Gly Ile Leu Gly Pro Gln Leu His Ala Asp
1 5 10 15
Val Gly Asp Lys Val Lys
20
<210> 106
<211> 23
<212> PRT
<213> Homo sapiens
<400> 106
Ala Glu Glu His Thr Val Val Leu Thr Val Thr Gly Glu Pro Cys His
1 5 10 15
Phe Pro Phe Gln Tyr His Arg
20
<210> 107
<211> 7
<212> PRT
<213> Homo sapiens
<400> 107
Ala Glu Glu Ile Leu Ser Arg
1 5
<210> 108
<211> 7
<212> PRT
<213> Homo sapiens
<400> 108
Ala Glu Glu Leu Leu Ser Arg
1 5
<210> 109
<211> 6
<212> PRT
<213> Homo sapiens
<400> 109
Ala Glu Phe Ala Glu Arg
1 5
<210> 110
<211> 8
<212> PRT
<213> Homo sapiens
<400> 110
Ala Glu Phe Ala Glu Val Ser Lys
1 5
<210> 111
<211> 9
<212> PRT
<213> Homo sapiens
<400> 111
Ala Glu Phe Gln Asp Ala Leu Glu Lys
1 5
<210> 112
<211> 10
<212> PRT
<213> Homo sapiens
<400> 112
Ala Glu Gly Asp Val Ala Ala Leu Asn Arg
1 5 10
<210> 113
<211> 11
<212> PRT
<213> Homo sapiens
<400> 113
Ala Glu Gly Asp Val Ala Ala Leu Asn Arg Arg
1 5 10
<210> 114
<211> 8
<212> PRT
<213> Homo sapiens
<400> 114
Ala Glu Ile Glu Tyr Leu Glu Lys
1 5
<210> 115
<211> 9
<212> PRT
<213> Homo sapiens
<400> 115
Ala Glu Ile Ser Phe Glu Asp Arg Lys
1 5
<210> 116
<211> 12
<212> PRT
<213> Homo sapiens
<400> 116
Ala Glu Leu Asp Arg Glu Asp Phe Glu His Val Lys
1 5 10
<210> 117
<211> 8
<212> PRT
<213> Homo sapiens
<400> 117
Ala Glu Leu Gln Glu Gly Ala Arg
1 5
<210> 118
<211> 13
<212> PRT
<213> Homo sapiens
<400> 118
Ala Glu Met Ala Asp Gln Ala Ala Ala Trp Leu Thr Arg
1 5 10
<210> 119
<211> 16
<212> PRT
<213> Homo sapiens
<400> 119
Ala Glu Pro His Phe Leu Ser Ile Leu Gln His Leu Leu Leu Val Arg
1 5 10 15
<210> 120
<211> 13
<212> PRT
<213> Homo sapiens
<400> 120
Ala Glu Pro Leu Ala Phe Thr Phe Ser His Asp Tyr Lys
1 5 10
<210> 121
<211> 23
<212> PRT
<213> Homo sapiens
<400> 121
Ala Glu Pro Leu Ala Phe Thr Phe Ser His Asp Tyr Lys Gly Ser Thr
1 5 10 15
Ser His His Leu Val Ser Arg
20
<210> 122
<211> 12
<212> PRT
<213> Homo sapiens
<400> 122
Ala Glu Thr Gly Asp Lys Val Tyr Val His Leu Lys
1 5 10
<210> 123
<211> 10
<212> PRT
<213> Homo sapiens
<400> 123
Ala Glu Val Asp Asp Val Ile Gln Val Arg
1 5 10
<210> 124
<211> 7
<212> PRT
<213> Homo sapiens
<400> 124
Ala Glu Val Ser Glu Leu Lys
1 5
<210> 125
<211> 43
<212> PRT
<213> Homo sapiens
<400> 125
Ala Phe Ala Val Ala Phe Gly Ile Asn Val Leu Ala Ala Asn Val His
1 5 10 15
His Pro Val Leu Gly Met Thr Gly Ser Gly Ile His Thr Pro Leu Glu
20 25 30
Ser Phe Trp Tyr His Asp Met Glu Asn Pro Lys
35 40
<210> 126
<211> 9
<212> PRT
<213> Homo sapiens
<400> 126
Ala Phe Asp Ile Cys Pro Leu Val Lys
1 5
<210> 127
<211> 7
<212> PRT
<213> Homo sapiens
<400> 127
Ala Phe Glu Glu Ala Glu Lys
1 5
<210> 128
<211> 15
<212> PRT
<213> Homo sapiens
<400> 128
Ala Phe Gly His His Ala Val Ser Leu Leu Asp Gly Gly Leu Arg
1 5 10 15
<210> 129
<211> 8
<212> PRT
<213> Homo sapiens
<400> 129
Ala Phe His Phe Tyr Leu Thr Arg
1 5
<210> 130
<211> 27
<212> PRT
<213> Homo sapiens
<400> 130
Ala Phe His Thr Ala Ser Val Leu Gly Asn Tyr Met Val Val Tyr Gly
1 5 10 15
Gly Asn Val His Thr His Tyr Gln Glu Glu Lys
20 25
<210> 131
<211> 12
<212> PRT
<213> Homo sapiens
<400> 131
Ala Phe Ile Gln Leu Trp Ala Phe Asp Ala Val Lys
1 5 10
<210> 132
<211> 20
<212> PRT
<213> Homo sapiens
<400> 132
Ala Phe Ile Thr Asn Phe Ser Met Ile Ile Asp Gly Met Thr Tyr Pro
1 5 10 15
Gly Ile Ile Lys
20
<210> 133
<211> 9
<212> PRT
<213> Homo sapiens
<400> 133
Ala Phe Lys Ala Trp Ala Val Ala Arg
1 5
<210> 134
<211> 23
<212> PRT
<213> Homo sapiens
<400> 134
Ala Phe Leu Glu Val Asn Glu Glu Gly Ser Glu Ala Ala Ala Ser Thr
1 5 10 15
Ala Val Val Ile Ala Gly Arg
20
<210> 135
<211> 7
<212> PRT
<213> Homo sapiens
<400> 135
Ala Phe Leu Leu Thr Pro Arg
1 5
<210> 136
<211> 14
<212> PRT
<213> Homo sapiens
<400> 136
Ala Phe Leu Ser Ser His Cys Tyr Asn Ala Ala Thr Ile Lys
1 5 10
<210> 137
<211> 15
<212> PRT
<213> Homo sapiens
<400> 137
Ala Phe Leu Ser Ser His Leu Gln Asp Leu Ser Thr Ile Val Arg
1 5 10 15
<210> 138
<211> 6
<212> PRT
<213> Homo sapiens
<400> 138
Ala Phe Asn Ala Val Lys
1 5
<210> 139
<211> 12
<212> PRT
<213> Homo sapiens
<400> 139
Ala Phe Gln Ala Val Gln Asn Leu Pro Thr Lys Lys
1 5 10
<210> 140
<211> 17
<212> PRT
<213> Homo sapiens
<400> 140
Ala Phe Gln Pro Phe Phe Val Glu Leu Thr Met Pro Tyr Ser Val Ile
1 5 10 15
Arg
<210> 141
<211> 7
<212> PRT
<213> Homo sapiens
<400> 141
Ala Phe Gln Tyr His Ser Lys
1 5
<210> 142
<211> 14
<212> PRT
<213> Homo sapiens
<400> 142
Ala Phe Ser Asp Arg Asn Thr Leu Ile Ile Tyr Leu Asp Lys
1 5 10
<210> 143
<211> 7
<212> PRT
<213> Homo sapiens
<400> 143
Ala Phe Ser Ser Tyr Gln Lys
1 5
<210> 144
<211> 8
<212> PRT
<213> Homo sapiens
<400> 144
Ala Phe Ser Val Asn Ile Phe Lys
1 5
<210> 145
<211> 6
<212> PRT
<213> Homo sapiens
<400> 145
Ala Phe Thr Asn Ser Lys
1 5
<210> 146
<211> 6
<212> PRT
<213> Homo sapiens
<400> 146
Ala Phe Val Phe Pro Lys
1 5
<210> 147
<211> 10
<212> PRT
<213> Homo sapiens
<400> 147
Ala Phe Trp Leu Asp Val Ser His Asn Arg
1 5 10
<210> 148
<211> 9
<212> PRT
<213> Homo sapiens
<400> 148
Ala Gly Ala Glu Pro Ala Ser Glu Arg
1 5
<210> 149
<211> 10
<212> PRT
<213> Homo sapiens
<400> 149
Ala Gly Ala His Leu Gln Gly Gly Ala Lys
1 5 10
<210> 150
<211> 13
<212> PRT
<213> Homo sapiens
<400> 150
Ala Gly Ala Leu Asn Ser Asn Asp Ala Phe Val Leu Lys
1 5 10
<210> 151
<211> 12
<212> PRT
<213> Homo sapiens
<400> 151
Ala Gly Ala Leu Gln Leu Leu Leu Val Gly Asp Lys
1 5 10
<210> 152
<211> 23
<212> PRT
<213> Homo sapiens
<400> 152
Ala Gly Asp Glu Ala Val Phe Ala Gln Tyr Asp Ser Phe His Val Asp
1 5 10 15
Ser Ala Ala Glu Tyr Tyr Arg
20
<210> 153
<211> 14
<212> PRT
<213> Homo sapiens
<400> 153
Ala Gly Asp Phe Leu Glu Ala Asn Tyr Met Asn Leu Gln Arg
1 5 10
<210> 154
<211> 15
<212> PRT
<213> Homo sapiens
<400> 154
Ala Gly Glu Ala Gly Lys Leu Glu Glu Val Met Gln Glu Leu Arg
1 5 10 15
<210> 155
<211> 25
<212> PRT
<213> Homo sapiens
<400> 155
Ala Gly Glu Leu Glu Val Phe Asn Gly Tyr Phe Val His Phe Phe Ala
1 5 10 15
Pro Asp Asn Leu Asp Pro Ile Pro Lys
20 25
<210> 156
<211> 11
<212> PRT
<213> Homo sapiens
<400> 156
Ala Gly Glu Gln Asp Ala Thr Ile His Leu Lys
1 5 10
<210> 157
<211> 14
<212> PRT
<213> Homo sapiens
<400> 157
Ala Gly Glu Gln Val Thr Tyr Thr Cys Ala Thr Tyr Tyr Lys
1 5 10
<210> 158
<211> 10
<212> PRT
<213> Homo sapiens
<400> 158
Ala Gly Glu Val Gln Glu Pro Glu Leu Arg
1 5 10
<210> 159
<211> 10
<212> PRT
<213> Homo sapiens
<400> 159
Ala Gly Phe Ala Gly Asp Asp Ala Pro Arg
1 5 10
<210> 160
<211> 40
<212> PRT
<213> Homo sapiens
<400> 160
Ala Gly Phe Glu Trp Asn Glu Asp Gly Ala Gly Thr Thr Pro Ser Pro
1 5 10 15
Gly Leu Gln Pro Ala His Leu Thr Phe Pro Leu Asp Tyr His Leu Asn
20 25 30
Gln Pro Phe Ile Phe Val Leu Arg
35 40
<210> 161
<211> 7
<212> PRT
<213> Homo sapiens
<400> 161
Ala Gly Phe Leu Asp Leu Lys
1 5
<210> 162
<211> 11
<212> PRT
<213> Homo sapiens
<400> 162
Ala Gly Phe Ser Trp Ile Glu Val Thr Phe Lys
1 5 10
<210> 163
<211> 12
<212> PRT
<213> Homo sapiens
<400> 163
Ala Gly Gly Ser Trp Asp Leu Ala Val Gln Glu Arg
1 5 10
<210> 164
<211> 11
<212> PRT
<213> Homo sapiens
<400> 164
Ala Gly His Ile Ala Trp Thr Ser Ser Gly Lys
1 5 10
<210> 165
<211> 5
<212> PRT
<213> Homo sapiens
<400> 165
Ala Gly Ile Ile Lys
1 5
<210> 166
<211> 5
<212> PRT
<213> Homo sapiens
<400> 166
Ala Gly Ile Leu Lys
1 5
<210> 167
<211> 8
<212> PRT
<213> Homo sapiens
<400> 167
Ala Gly Ile Ser Phe Ile Ile Lys
1 5
<210> 168
<211> 11
<212> PRT
<213> Homo sapiens
<400> 168
Ala Gly Lys Glu Pro Gly Leu Gln Ile Trp Arg
1 5 10
<210> 169
<211> 16
<212> PRT
<213> Homo sapiens
<400> 169
Ala Gly Leu Ala Ala Ser Leu Ala Gly Pro His Ser Ile Val Gly Arg
1 5 10 15
<210> 170
<211> 5
<212> PRT
<213> Homo sapiens
<400> 170
Ala Gly Leu Glu Lys
1 5
<210> 171
<211> 5
<212> PRT
<213> Homo sapiens
<400> 171
Ala Gly Leu Leu Lys
1 5
<210> 172
<211> 14
<212> PRT
<213> Homo sapiens
<400> 172
Ala Gly Leu Leu Arg Pro Asp Tyr Ala Leu Leu Gly His Arg
1 5 10
<210> 173
<211> 14
<212> PRT
<213> Homo sapiens
<400> 173
Ala Gly Leu Gln Ala Phe Phe Gln Val Gln Glu Cys Asn Lys
1 5 10
<210> 174
<211> 11
<212> PRT
<213> Homo sapiens
<400> 174
Ala Gly Leu Gln Ser Leu Glu Ala Ser Gly Arg
1 5 10
<210> 175
<211> 10
<212> PRT
<213> Homo sapiens
<400> 175
Ala Gly Leu Ser His Met Leu Ile Gln Arg
1 5 10
<210> 176
<211> 14
<212> PRT
<213> Homo sapiens
<400> 176
Ala Gly Asn Asn Met Leu Leu Val Gly Val His Gly Pro Arg
1 5 10
<210> 177
<211> 15
<212> PRT
<213> Homo sapiens
<400> 177
Ala Gly Pro His Cys Pro Thr Ala Gln Leu Ile Ala Thr Leu Lys
1 5 10 15
<210> 178
<211> 7
<212> PRT
<213> Homo sapiens
<400> 178
Ala Gly Gln Leu Ser Val Lys
1 5
<210> 179
<211> 14
<212> PRT
<213> Homo sapiens
<400> 179
Ala Gly Thr Phe Phe Trp Ser Val Val Ile Pro His Glu Arg
1 5 10
<210> 180
<211> 14
<212> PRT
<213> Homo sapiens
<400> 180
Ala Gly Thr Pro Tyr Thr Val Thr Leu His Gly Glu Val Arg
1 5 10
<210> 181
<211> 17
<212> PRT
<213> Homo sapiens
<400> 181
Ala Gly Thr Gln Ile Glu Asn Ile Glu Glu Asp Phe Arg Asp Gly Leu
1 5 10 15
Lys
<210> 182
<211> 10
<212> PRT
<213> Homo sapiens
<400> 182
Ala Gly Val Glu Thr Thr Lys Pro Ser Lys
1 5 10
<210> 183
<211> 11
<212> PRT
<213> Homo sapiens
<400> 183
Ala Gly Val Leu Ala His Leu Glu Glu Glu Arg
1 5 10
<210> 184
<211> 20
<212> PRT
<213> Homo sapiens
<400> 184
Ala His Phe Ser Pro Ser Asn Ile Ile Leu Asp Phe Pro Ala Ala Gly
1 5 10 15
Ser Ala Ala Arg
20
<210> 185
<211> 9
<212> PRT
<213> Homo sapiens
<400> 185
Ala His Ile Pro Pro Leu Gly Leu Lys
1 5
<210> 186
<211> 14
<212> PRT
<213> Homo sapiens
<400> 186
Ala His Leu Asp Ile Ala Gly Ser Leu Glu Gly His Leu Arg
1 5 10
<210> 187
<211> 6
<212> PRT
<213> Homo sapiens
<400> 187
Ala His Leu Leu Leu Lys
1 5
<210> 188
<211> 12
<212> PRT
<213> Homo sapiens
<400> 188
Ala His Leu Leu Ser Leu Val Asp Val Met Gln Arg
1 5 10
<210> 189
<211> 6
<212> PRT
<213> Homo sapiens
<400> 189
Ala His Leu Asn Ile Lys
1 5
<210> 190
<211> 15
<212> PRT
<213> Homo sapiens
<400> 190
Ala His Asn Ala Phe Gly Gly Glu Gly Val Tyr Ala Ile Ala Arg
1 5 10 15
<210> 191
<211> 13
<212> PRT
<213> Homo sapiens
<400> 191
Ala His Ser Ser Met Val Gly Val Asn Leu Pro Gln Lys
1 5 10
<210> 192
<211> 17
<212> PRT
<213> Homo sapiens
<400> 192
Ala His Thr Asp Val Gly Pro Gly Pro Glu Ser Ser Pro Val Leu Val
1 5 10 15
Arg
<210> 193
<211> 17
<212> PRT
<213> Homo sapiens
<400> 193
Ala His Thr Ser Phe Gln Ile Ser Leu Ser Val Ser Tyr Thr Gly Ser
1 5 10 15
Arg
<210> 194
<211> 7
<212> PRT
<213> Homo sapiens
<400> 194
Ala His Val Asp Ala Leu Arg
1 5
<210> 195
<211> 7
<212> PRT
<213> Homo sapiens
<400> 195
Ala His Val Asp Glu Phe Lys
1 5
<210> 196
<211> 20
<212> PRT
<213> Homo sapiens
<400> 196
Ala His Val Ile Val Met Ala Ala Thr Asn Arg Pro Asn Ser Ile Asp
1 5 10 15
Pro Ala Leu Arg
20
<210> 197
<211> 13
<212> PRT
<213> Homo sapiens
<400> 197
Ala His Val Ser Phe Lys Pro Thr Val Ala Gln Gln Arg
1 5 10
<210> 198
<211> 6
<212> PRT
<213> Homo sapiens
<400> 198
Ala His Tyr Asp Leu Arg
1 5
<210> 199
<211> 14
<212> PRT
<213> Homo sapiens
<400> 199
Ala His Tyr Gly Gly Phe Thr Val Gln Asn Glu Ala Asn Lys
1 5 10
<210> 200
<211> 21
<212> PRT
<213> Homo sapiens
<400> 200
Ala His Tyr Gly Gly Phe Thr Val Gln Asn Glu Ala Asn Lys Tyr Gln
1 5 10 15
Ile Ser Val Asn Lys
20
<210> 201
<211> 38
<212> PRT
<213> Homo sapiens
<400> 201
Ala Ile Ala Ala Asn Glu Ala Asp Ala Val Thr Leu Asp Ala Gly Leu
1 5 10 15
Val Tyr Asp Ala Tyr Leu Ala Pro Asn Asn Leu Lys Pro Val Val Ala
20 25 30
Glu Phe Tyr Gly Ser Lys
35
<210> 202
<211> 52
<212> PRT
<213> Homo sapiens
<400> 202
Ala Ile Ala Ala Asn Glu Ala Asp Ala Val Thr Leu Asp Ala Gly Leu
1 5 10 15
Val Tyr Asp Ala Tyr Leu Ala Pro Asn Asn Leu Lys Pro Val Val Ala
20 25 30
Glu Phe Tyr Gly Ser Lys Glu Asp Pro Gln Thr Phe Tyr Tyr Ala Val
35 40 45
Ala Val Val Lys
50
<210> 203
<211> 21
<212> PRT
<213> Homo sapiens
<400> 203
Ala Ile Ala Tyr Ser Ser Leu Ser Gln Ser Tyr Leu Tyr Ile Asp Trp
1 5 10 15
Thr Asp Asn His Lys
20
<210> 204
<211> 17
<212> PRT
<213> Homo sapiens
<400> 204
Ala Ile Asp Glu Asp Cys Ser Gln Tyr Glu Pro Ile Pro Gly Ser Gln
1 5 10 15
Lys
<210> 205
<211> 7
<212> PRT
<213> Homo sapiens
<400> 205
Ala Ile Asp Leu Val Thr Lys
1 5
<210> 206
<211> 12
<212> PRT
<213> Homo sapiens
<400> 206
Ala Ile Glu Asp Tyr Ile Asn Glu Phe Ser Val Arg
1 5 10
<210> 207
<211> 13
<212> PRT
<213> Homo sapiens
<400> 207
Ala Ile Glu Asp Tyr Ile Asn Glu Phe Ser Val Arg Lys
1 5 10
<210> 208
<211> 9
<212> PRT
<213> Homo sapiens
<400> 208
Ala Ile Glu Asn Glu Leu Leu Ala Arg
1 5
<210> 209
<211> 13
<212> PRT
<213> Homo sapiens
<400> 209
Ala Ile Phe Ser Val Gly Pro Val Ser Pro Asn Arg Arg
1 5 10
<210> 210
<211> 13
<212> PRT
<213> Homo sapiens
<400> 210
Ala Ile Phe Ser Val Gly Pro Val Ser Pro Ser Arg Arg
1 5 10
<210> 211
<211> 10
<212> PRT
<213> Homo sapiens
<400> 211
Ala Ile Phe Tyr Met Asn Asn Pro Ser Arg
1 5 10
<210> 212
<211> 11
<212> PRT
<213> Homo sapiens
<400> 212
Ala Ile Gly Pro Ser Gln Thr His Thr Ile Arg
1 5 10
<210> 213
<211> 19
<212> PRT
<213> Homo sapiens
<400> 213
Ala Ile Gly Ser Ala Ser Glu Gly Ala Gln Ser Ser Leu Gln Glu Val
1 5 10 15
Tyr His Lys
<210> 214
<211> 11
<212> PRT
<213> Homo sapiens
<400> 214
Ala Ile Gly Tyr Leu Asn Thr Gly Tyr Gln Arg
1 5 10
<210> 215
<211> 18
<212> PRT
<213> Homo sapiens
<400> 215
Ala Ile His Cys Pro Arg Pro His Asp Phe Glu Asn Gly Glu Tyr Trp
1 5 10 15
Pro Arg
<210> 216
<211> 10
<212> PRT
<213> Homo sapiens
<400> 216
Ala Ile His Leu Asp Leu Glu Glu Tyr Arg
1 5 10
<210> 217
<211> 7
<212> PRT
<213> Homo sapiens
<400> 217
Ala Ile His Leu Leu Leu Arg
1 5
<210> 218
<211> 8
<212> PRT
<213> Homo sapiens
<400> 218
Ala Ile His Ser Trp Leu Thr Arg
1 5
<210> 219
<211> 41
<212> PRT
<213> Homo sapiens
<400> 219
Ala Ile His Val His Gln Phe Gly Asp Leu Ser Gln Gly Cys Glu Ser
1 5 10 15
Thr Gly Pro His Tyr Asn Pro Leu Ala Val Pro His Pro Gln His Pro
20 25 30
Gly Asp Phe Gly Asn Phe Ala Val Arg
35 40
<210> 220
<211> 6
<212> PRT
<213> Homo sapiens
<400> 220
Ala Ile Ile Ser Asn Lys
1 5
<210> 221
<211> 12
<212> PRT
<213> Homo sapiens
<400> 221
Ala Ile Lys Ala Asn Val Phe Val Gln Leu Pro Arg
1 5 10
<210> 222
<211> 7
<212> PRT
<213> Homo sapiens
<400> 222
Ala Ile Leu Phe Val Pro Arg
1 5
<210> 223
<211> 5
<212> PRT
<213> Homo sapiens
<400> 223
Ala Ile Met Glu Lys
1 5
<210> 224
<211> 10
<212> PRT
<213> Homo sapiens
<400> 224
Ala Ile Met Glu Lys Leu Glu Met Ser Lys
1 5 10
<210> 225
<211> 18
<212> PRT
<213> Homo sapiens
<400> 225
Ala Ile Met Thr Tyr Val Ser Ser Phe Tyr His Ala Phe Ser Gly Ala
1 5 10 15
Gln Lys
<210> 226
<211> 9
<212> PRT
<213> Homo sapiens
<400> 226
Ala Ile Pro Val Thr Gln Tyr Leu Lys
1 5
<210> 227
<211> 7
<212> PRT
<213> Homo sapiens
<400> 227
Ala Ile Gln Glu Met Arg Arg
1 5
<210> 228
<211> 23
<212> PRT
<213> Homo sapiens
<400> 228
Ala Ile Gln Leu Thr Tyr Asn Pro Asp Glu Ser Ser Lys Pro Asn Met
1 5 10 15
Ile Asp Ala Ala Thr Leu Lys
20
<210> 229
<211> 6
<212> PRT
<213> Homo sapiens
<400> 229
Ala Ile Gln Ser Leu Lys
1 5
<210> 230
<211> 6
<212> PRT
<213> Homo sapiens
<400> 230
Ala Ile Gln Val Val Arg
1 5
<210> 231
<211> 28
<212> PRT
<213> Homo sapiens
<400> 231
Ala Ile Ser Gly Gly Ser Ile Gln Ile Glu Asn Gly Tyr Phe Val His
1 5 10 15
Tyr Phe Ala Pro Glu Gly Leu Thr Thr Met Pro Lys
20 25
<210> 232
<211> 15
<212> PRT
<213> Homo sapiens
<400> 232
Ala Ile Ser Gly Leu Thr Ile Asp Gly His Ala Val Gly Ala Lys
1 5 10 15
<210> 233
<211> 9
<212> PRT
<213> Homo sapiens
<400> 233
Ala Ile Ser Val Val Ser Arg Leu Lys
1 5
<210> 234
<211> 23
<212> PRT
<213> Homo sapiens
<400> 234
Ala Ile Thr Pro Pro His Pro Ala Ser Gln Ala Asn Ile Ile Phe Asp
1 5 10 15
Ile Thr Glu Gly Asn Leu Arg
20
<210> 235
<211> 12
<212> PRT
<213> Homo sapiens
<400> 235
Ala Lys Asp Leu His Leu Ser Asp Val Phe Leu Lys
1 5 10
<210> 236
<211> 18
<212> PRT
<213> Homo sapiens
<400> 236
Ala Lys Glu Gln Tyr Ala Val Val Gly His Ser Ala His Ile Val Thr
1 5 10 15
Leu Lys
<210> 237
<211> 12
<212> PRT
<213> Homo sapiens
<400> 237
Ala Lys Phe Glu Glu Leu Asn Met Asp Leu Phe Arg
1 5 10
<210> 238
<211> 11
<212> PRT
<213> Homo sapiens
<400> 238
Ala Lys Ile Asp Gln Asn Val Glu Glu Leu Lys
1 5 10
<210> 239
<211> 11
<212> PRT
<213> Homo sapiens
<400> 239
Ala Lys Leu Glu Glu Gln Ala Gln Gln Ile Arg
1 5 10
<210> 240
<211> 17
<212> PRT
<213> Homo sapiens
<400> 240
Ala Lys Leu Gly Asn Phe Pro Trp Gln Ala Phe Thr Ser Ile His Gly
1 5 10 15
Arg
<210> 241
<211> 17
<212> PRT
<213> Homo sapiens
<400> 241
Ala Lys Leu Ile Ala Leu Thr Leu Leu Gly Met Gly Leu Ala Leu Phe
1 5 10 15
Arg
<210> 242
<211> 13
<212> PRT
<213> Homo sapiens
<400> 242
Ala Lys Leu Pro Asp Ala Thr Pro Thr Glu Leu Ala Lys
1 5 10
<210> 243
<211> 11
<212> PRT
<213> Homo sapiens
<400> 243
Ala Lys Met Glu Ser Leu Gly Ile Thr Ser Arg
1 5 10
<210> 244
<211> 9
<212> PRT
<213> Homo sapiens
<400> 244
Ala Lys Pro Ala Leu Glu Asp Leu Arg
1 5
<210> 245
<211> 14
<212> PRT
<213> Homo sapiens
<400> 245
Ala Lys Pro Ser Ala Pro Val Val Ser Gly Pro Ala Ala Arg
1 5 10
<210> 246
<211> 14
<212> PRT
<213> Homo sapiens
<400> 246
Ala Lys Pro Ser Ala Pro Val Val Ser Gly Pro Ala Val Arg
1 5 10
<210> 247
<211> 12
<212> PRT
<213> Homo sapiens
<400> 247
Ala Lys Val Gln Pro Tyr Leu Asp Asp Phe Gln Lys
1 5 10
<210> 248
<211> 16
<212> PRT
<213> Homo sapiens
<400> 248
Ala Lys Trp Glu Met Pro Phe Asp Pro Gln Asp Thr His Gln Ser Arg
1 5 10 15
<210> 249
<211> 7
<212> PRT
<213> Homo sapiens
<400> 249
Ala Leu Ala Glu Asp Val Lys
1 5
<210> 250
<211> 7
<212> PRT
<213> Homo sapiens
<400> 250
Ala Leu Ala Gly Asn Pro Lys
1 5
<210> 251
<211> 22
<212> PRT
<213> Homo sapiens
<400> 251
Ala Leu Ala Leu Pro Pro Leu Gly Leu Ala Pro Leu Leu Asn Leu Trp
1 5 10 15
Ala Lys Pro Gln Gly Arg
20
<210> 252
<211> 9
<212> PRT
<213> Homo sapiens
<400> 252
Ala Leu Ala Met Gly Tyr Lys Pro Lys
1 5
<210> 253
<211> 8
<212> PRT
<213> Homo sapiens
<400> 253
Ala Leu Ala Pro Glu Tyr Ala Lys
1 5
<210> 254
<211> 8
<212> PRT
<213> Homo sapiens
<400> 254
Ala Leu Ala Ser Ile Asp Ser Lys
1 5
<210> 255
<211> 11
<212> PRT
<213> Homo sapiens
<400> 255
Ala Leu Ala Ser Gln Leu Gln Asp Ser Leu Lys
1 5 10
<210> 256
<211> 7
<212> PRT
<213> Homo sapiens
<400> 256
Ala Leu Ala Thr Tyr Ser Lys
1 5
<210> 257
<211> 11
<212> PRT
<213> Homo sapiens
<400> 257
Ala Leu Asp Phe Ala Val Gly Glu Tyr Asn Lys
1 5 10
<210> 258
<211> 11
<212> PRT
<213> Homo sapiens
<400> 258
Ala Leu Asp Gly Ala Phe Thr Glu Glu Asn Arg
1 5 10
<210> 259
<211> 7
<212> PRT
<213> Homo sapiens
<400> 259
Ala Leu Asp Leu Ile Asn Lys
1 5
<210> 260
<211> 8
<212> PRT
<213> Homo sapiens
<400> 260
Ala Leu Asp Leu Ile Asn Lys Arg
1 5
<210> 261
<211> 7
<212> PRT
<213> Homo sapiens
<400> 261
Ala Leu Asp Leu Ser Leu Lys
1 5
<210> 262
<211> 13
<212> PRT
<213> Homo sapiens
<400> 262
Ala Leu Asp Gln Tyr Leu Met Glu Phe Asn Ala Cys Arg
1 5 10
<210> 263
<211> 11
<212> PRT
<213> Homo sapiens
<400> 263
Ala Leu Asp Val Met Val Ser Thr Phe His Lys
1 5 10
<210> 264
<211> 10
<212> PRT
<213> Homo sapiens
<400> 264
Ala Leu Glu Ala Thr Thr Glu His Ile Arg
1 5 10
<210> 265
<211> 12
<212> PRT
<213> Homo sapiens
<400> 265
Ala Leu Glu Glu Ser Asn Tyr Glu Leu Glu Gly Lys
1 5 10
<210> 266
<211> 11
<212> PRT
<213> Homo sapiens
<400> 266
Ala Leu Glu Phe Leu Gln Leu His Asn Gly Arg
1 5 10
<210> 267
<211> 19
<212> PRT
<213> Homo sapiens
<400> 267
Ala Leu Glu Ile Leu Gln Glu Glu Asp Leu Ile Asp Glu Asp Asp Ile
1 5 10 15
Pro Val Arg
<210> 268
<211> 9
<212> PRT
<213> Homo sapiens
<400> 268
Ala Leu Glu Leu Glu Gln Glu Arg Lys
1 5
<210> 269
<211> 7
<212> PRT
<213> Homo sapiens
<400> 269
Ala Leu Glu Asn Ser Pro Lys
1 5
<210> 270
<211> 8
<212> PRT
<213> Homo sapiens
<400> 270
Ala Leu Glu Gln Ala Leu Glu Lys
1 5
<210> 271
<211> 11
<212> PRT
<213> Homo sapiens
<400> 271
Ala Leu Glu Gln Asp Leu Pro Val Asn Ile Lys
1 5 10
<210> 272
<211> 17
<212> PRT
<213> Homo sapiens
<400> 272
Ala Leu Glu Ser Pro Glu Arg Pro Phe Leu Ala Ile Leu Gly Gly Ala
1 5 10 15
Lys
<210> 273
<211> 17
<212> PRT
<213> Homo sapiens
<400> 273
Ala Leu Glu Val Ser Gln Ala Pro Val Ile Phe Ser His Ser Ala Ala
1 5 10 15
Arg
<210> 274
<211> 9
<212> PRT
<213> Homo sapiens
<400> 274
Ala Leu Phe Val Ser Glu Glu Glu Lys
1 5
<210> 275
<211> 10
<212> PRT
<213> Homo sapiens
<400> 275
Ala Leu Phe Val Ser Glu Glu Glu Lys Lys
1 5 10
<210> 276
<211> 10
<212> PRT
<213> Homo sapiens
<400> 276
Ala Leu Gly Asp Leu Ile Ser Ala Thr Lys
1 5 10
<210> 277
<211> 20
<212> PRT
<213> Homo sapiens
<400> 277
Ala Leu Gly Gly Asp Leu Ala Ser Ile Asn Asn Lys Glu Glu Gln Gln
1 5 10 15
Thr Ile Trp Arg
20
<210> 278
<211> 11
<212> PRT
<213> Homo sapiens
<400> 278
Ala Leu Gly His Leu Asp Leu Ser Gly Asn Arg
1 5 10
<210> 279
<211> 23
<212> PRT
<213> Homo sapiens
<400> 279
Ala Leu Gly Ile Ser Pro Phe His Glu His Ala Glu Val Val Phe Thr
1 5 10 15
Ala Asn Asp Ser Gly Pro Arg
20
<210> 280
<211> 24
<212> PRT
<213> Homo sapiens
<400> 280
Ala Leu Gly Ile Ser Pro Phe His Glu His Ala Glu Val Val Phe Thr
1 5 10 15
Ala Asn Asp Ser Gly Pro Arg Arg
20
<210> 281
<211> 7
<212> PRT
<213> Homo sapiens
<400> 281
Ala Leu His Phe Val Phe Lys
1 5
<210> 282
<211> 14
<212> PRT
<213> Homo sapiens
<400> 282
Ala Leu His Gln Val Phe Glu His Met Leu Asp Val Ser Lys
1 5 10
<210> 283
<211> 14
<212> PRT
<213> Homo sapiens
<400> 283
Ala Leu His Ser Asp Arg Pro Pro Ser Ala Ser Gln Pro Arg
1 5 10
<210> 284
<211> 8
<212> PRT
<213> Homo sapiens
<400> 284
Ala Leu His Val Thr Asn Ile Lys
1 5
<210> 285
<211> 16
<212> PRT
<213> Homo sapiens
<400> 285
Ala Leu Ile Glu Val Leu Gln Pro Leu Ile Ala Glu His Gln Ala Arg
1 5 10 15
<210> 286
<211> 15
<212> PRT
<213> Homo sapiens
<400> 286
Ala Leu Ile Phe Val Ser His Gly Ala Gly Glu His Ser Gly Arg
1 5 10 15
<210> 287
<211> 18
<212> PRT
<213> Homo sapiens
<400> 287
Ala Leu Lys Tyr Glu Val Gln Gly Glu Val Phe Thr Lys Pro Gln Leu
1 5 10 15
Trp Pro
<210> 288
<211> 9
<212> PRT
<213> Homo sapiens
<400> 288
Ala Leu Leu Ala Phe Gln Glu Ser Lys
1 5
<210> 289
<211> 15
<212> PRT
<213> Homo sapiens
<400> 289
Ala Leu Leu Ala Tyr Ala Phe Ala Leu Ala Gly Asn Gln Asp Lys
1 5 10 15
<210> 290
<211> 16
<212> PRT
<213> Homo sapiens
<400> 290
Ala Leu Leu Ala Tyr Ala Phe Ala Leu Ala Gly Asn Gln Asp Lys Arg
1 5 10 15
<210> 291
<211> 12
<212> PRT
<213> Homo sapiens
<400> 291
Ala Leu Leu Ala Tyr Ala Phe Ser Leu Leu Gly Lys
1 5 10
<210> 292
<211> 7
<212> PRT
<213> Homo sapiens
<400> 292
Ala Leu Leu Phe Val Pro Arg
1 5
<210> 293
<211> 15
<212> PRT
<213> Homo sapiens
<400> 293
Ala Leu Leu Val Gly Glu His Leu Asn Ile Ile Val Thr Pro Lys
1 5 10 15
<210> 294
<211> 14
<212> PRT
<213> Homo sapiens
<400> 294
Ala Leu Leu Val His Gly Gly His Arg Pro Ser Thr Ala Arg
1 5 10
<210> 295
<211> 8
<212> PRT
<213> Homo sapiens
<400> 295
Ala Leu Met Ala Ala Glu Asp Lys
1 5
<210> 296
<211> 8
<212> PRT
<213> Homo sapiens
<400> 296
Ala Leu Met Asp Glu Thr Met Lys
1 5
<210> 297
<211> 11
<212> PRT
<213> Homo sapiens
<400> 297
Ala Leu Met Asp Glu Thr Met Lys Glu Leu Lys
1 5 10
<210> 298
<211> 16
<212> PRT
<213> Homo sapiens
<400> 298
Ala Leu Asn His Leu Pro Leu Glu Tyr Asn Ser Ala Leu Tyr Ser Arg
1 5 10 15
<210> 299
<211> 11
<212> PRT
<213> Homo sapiens
<400> 299
Ala Leu Asn Ser Ile Ile Asp Val Tyr His Lys
1 5 10
<210> 300
<211> 12
<212> PRT
<213> Homo sapiens
<400> 300
Ala Leu Pro Glu Val His Tyr His Leu Gly Gln Lys
1 5 10
<210> 301
<211> 14
<212> PRT
<213> Homo sapiens
<400> 301
Ala Leu Pro Gly Glu Gln Gln Pro Leu His Ala Leu Thr Arg
1 5 10
<210> 302
<211> 20
<212> PRT
<213> Homo sapiens
<400> 302
Ala Leu Pro Gly Gln Leu Lys Pro Phe Glu Thr Leu Leu Ser Gln Asn
1 5 10 15
Gln Gly Gly Lys
20
<210> 303
<211> 15
<212> PRT
<213> Homo sapiens
<400> 303
Ala Leu Pro Leu Ala Leu Val Leu His Glu Leu Gly Ala Gly Arg
1 5 10 15
<210> 304
<211> 9
<212> PRT
<213> Homo sapiens
<400> 304
Ala Leu Pro Pro Leu Arg Leu Pro Arg
1 5
<210> 305
<211> 8
<212> PRT
<213> Homo sapiens
<400> 305
Ala Leu Pro Thr Thr Tyr Glu Lys
1 5
<210> 306
<211> 8
<212> PRT
<213> Homo sapiens
<400> 306
Ala Leu Gln Ala Ser Ala Leu Lys
1 5
<210> 307
<211> 12
<212> PRT
<213> Homo sapiens
<400> 307
Ala Leu Gln Asp Gln Leu Val Leu Val Ala Ala Lys
1 5 10
<210> 308
<211> 15
<212> PRT
<213> Homo sapiens
<400> 308
Ala Leu Gln Glu Arg Asp Tyr Ile Phe Gly Asn Tyr Ile Glu Arg
1 5 10 15
<210> 309
<211> 8
<212> PRT
<213> Homo sapiens
<400> 309
Ala Leu Gln Glu Tyr Ala Ala Lys
1 5
<210> 310
<211> 6
<212> PRT
<213> Homo sapiens
<400> 310
Ala Leu Gln Glu Tyr Arg
1 5
<210> 311
<211> 8
<212> PRT
<213> Homo sapiens
<400> 311
Ala Leu Gln Thr Glu Met Ala Arg
1 5
<210> 312
<211> 6
<212> PRT
<213> Homo sapiens
<400> 312
Ala Leu Gln Val Val Arg
1 5
<210> 313
<211> 15
<212> PRT
<213> Homo sapiens
<400> 313
Ala Leu Arg Asp Phe Ala Leu Gln Asn Pro Ser Ala Val Pro Arg
1 5 10 15
<210> 314
<211> 8
<212> PRT
<213> Homo sapiens
<400> 314
Ala Leu Ser Phe Phe His Gln Lys
1 5
<210> 315
<211> 7
<212> PRT
<213> Homo sapiens
<400> 315
Ala Leu Ser Leu His Ile Lys
1 5
<210> 316
<211> 10
<212> PRT
<213> Homo sapiens
<400> 316
Ala Leu Ser Asn Val Glu Gly Phe Glu Arg
1 5 10
<210> 317
<211> 11
<212> PRT
<213> Homo sapiens
<400> 317
Ala Leu Ser Ser Glu Trp Lys Pro Glu Ile Arg
1 5 10
<210> 318
<211> 12
<212> PRT
<213> Homo sapiens
<400> 318
Ala Leu Ser Thr Asp Pro Ala Ala Pro Asn Leu Lys
1 5 10
<210> 319
<211> 9
<212> PRT
<213> Homo sapiens
<400> 319
Ala Leu Thr Asp Met Pro Gln Met Arg
1 5
<210> 320
<211> 9
<212> PRT
<213> Homo sapiens
<400> 320
Ala Leu Thr Phe Glu Leu Thr Leu Arg
1 5
<210> 321
<211> 11
<212> PRT
<213> Homo sapiens
<400> 321
Ala Leu Thr Gly Gly Ile Ala His Leu Phe Lys
1 5 10
<210> 322
<211> 11
<212> PRT
<213> Homo sapiens
<400> 322
Ala Leu Thr Gln Thr Gly Gly Pro His Val Lys
1 5 10
<210> 323
<211> 7
<212> PRT
<213> Homo sapiens
<400> 323
Ala Leu Val Asp Thr Leu Lys
1 5
<210> 324
<211> 16
<212> PRT
<213> Homo sapiens
<400> 324
Ala Leu Val Glu Gly Val Asp Gln Leu Phe Thr Asp Tyr Gln Ile Lys
1 5 10 15
<210> 325
<211> 13
<212> PRT
<213> Homo sapiens
<400> 325
Ala Leu Val Glu Gln Gly Phe Thr Val Pro Glu Ile Lys
1 5 10
<210> 326
<211> 7
<212> PRT
<213> Homo sapiens
<400> 326
Ala Leu Val Ile Leu Ala Lys
1 5
<210> 327
<211> 21
<212> PRT
<213> Homo sapiens
<400> 327
Ala Leu Val Leu Ile Ala Phe Ala Gln Tyr Leu Gln Gln Cys Pro Phe
1 5 10 15
Glu Asp His Val Lys
20
<210> 328
<211> 10
<212> PRT
<213> Homo sapiens
<400> 328
Ala Leu Val Gln Gln Met Glu Gln Leu Arg
1 5 10
<210> 329
<211> 5
<212> PRT
<213> Homo sapiens
<400> 329
Ala Leu Trp Glu Lys
1 5
<210> 330
<211> 11
<212> PRT
<213> Homo sapiens
<400> 330
Ala Leu Trp Glu Lys Pro Phe Ile Ser Ser Arg
1 5 10
<210> 331
<211> 7
<212> PRT
<213> Homo sapiens
<400> 331
Ala Leu Tyr Ala Gln Ala Arg
1 5
<210> 332
<211> 12
<212> PRT
<213> Homo sapiens
<400> 332
Ala Leu Tyr Leu Gln Tyr Thr Asp Glu Thr Phe Arg
1 5 10
<210> 333
<211> 18
<212> PRT
<213> Homo sapiens
<400> 333
Ala Leu Tyr Leu Ser Asp Asn Asp Phe Glu Ile Leu Pro Pro Asp Ile
1 5 10 15
Gly Lys
<210> 334
<211> 9
<212> PRT
<213> Homo sapiens
<400> 334
Ala Leu Tyr Val His Gly Gly Tyr Lys
1 5
<210> 335
<211> 15
<212> PRT
<213> Homo sapiens
<400> 335
Ala Leu Tyr Trp Val Asn Gly Gln Val Pro Asp Gly Val Ser Lys
1 5 10 15
<210> 336
<211> 17
<212> PRT
<213> Homo sapiens
<400> 336
Ala Leu Tyr Tyr Asp Leu Ile Ser Ser Pro Asp Ile His Gly Thr Tyr
1 5 10 15
Lys
<210> 337
<211> 10
<212> PRT
<213> Homo sapiens
<400> 337
Ala Met Ala Val Glu Asp Ile Ile Ser Arg
1 5 10
<210> 338
<211> 10
<212> PRT
<213> Homo sapiens
<400> 338
Ala Met Phe Lys Asp Leu Leu Ser Ser Lys
1 5 10
<210> 339
<211> 7
<212> PRT
<213> Homo sapiens
<400> 339
Ala Met Leu Val Val His Lys
1 5
<210> 340
<211> 11
<212> PRT
<213> Homo sapiens
<400> 340
Ala Met Gln His Ile Ser Tyr Leu Asn Ser Arg
1 5 10
<210> 341
<211> 5
<212> PRT
<213> Homo sapiens
<400> 341
Ala Met Thr Ala Lys
1 5
<210> 342
<211> 19
<212> PRT
<213> Homo sapiens
<400> 342
Ala Asn Ala Gly Lys Pro Lys Asp Pro Thr Phe Ile Pro Ala Pro Ile
1 5 10 15
Gln Ala Lys
<210> 343
<211> 11
<212> PRT
<213> Homo sapiens
<400> 343
Ala Asn His Glu Glu Val Leu Ala Ala Gly Lys
1 5 10
<210> 344
<211> 6
<212> PRT
<213> Homo sapiens
<400> 344
Ala Asn Ile Asn Leu Lys
1 5
<210> 345
<211> 6
<212> PRT
<213> Homo sapiens
<400> 345
Ala Asn Leu Phe Asn Lys
1 5
<210> 346
<211> 12
<212> PRT
<213> Homo sapiens
<400> 346
Ala Asn Leu Phe Asn Lys Leu Val Thr Glu Leu Arg
1 5 10
<210> 347
<211> 15
<212> PRT
<213> Homo sapiens
<400> 347
Ala Asn Leu Gln Ser Val Pro His Ala Ser Ala Ser Arg Pro Arg
1 5 10 15
<210> 348
<211> 19
<212> PRT
<213> Homo sapiens
<400> 348
Ala Asn Pro Thr Val Thr Leu Phe Pro Pro Ser Ser Glu Glu Leu Gln
1 5 10 15
Ala Asn Lys
<210> 349
<211> 10
<212> PRT
<213> Homo sapiens
<400> 349
Ala Asn Arg Pro Phe Leu Val Phe Ile Arg
1 5 10
<210> 350
<211> 22
<212> PRT
<213> Homo sapiens
<400> 350
Ala Asn Arg Pro Phe Leu Val Phe Ile Arg Glu Val Pro Leu Asn Thr
1 5 10 15
Ile Ile Phe Met Gly Arg
20
<210> 351
<211> 8
<212> PRT
<213> Homo sapiens
<400> 351
Ala Asn Ser Phe Leu Gly Glu Lys
1 5
<210> 352
<211> 10
<212> PRT
<213> Homo sapiens
<400> 352
Ala Asn Thr Phe Leu Glu Glu Val Arg Lys
1 5 10
<210> 353
<211> 15
<212> PRT
<213> Homo sapiens
<400> 353
Ala Asn Thr Val Gln Glu Ala Thr Phe Gln Met Glu Leu Pro Lys
1 5 10 15
<210> 354
<211> 16
<212> PRT
<213> Homo sapiens
<400> 354
Ala Asn Thr Val Gln Glu Ala Thr Phe Gln Met Glu Leu Pro Lys Lys
1 5 10 15
<210> 355
<211> 9
<212> PRT
<213> Homo sapiens
<400> 355
Ala Asn Val Phe Val Gln Leu Pro Arg
1 5
<210> 356
<211> 6
<212> PRT
<213> Homo sapiens
<400> 356
Ala Pro Ala Asp Leu Arg
1 5
<210> 357
<211> 10
<212> PRT
<213> Homo sapiens
<400> 357
Ala Pro Asp Phe Val Phe Tyr Ala Pro Arg
1 5 10
<210> 358
<211> 8
<212> PRT
<213> Homo sapiens
<400> 358
Ala Pro Glu Gly Phe Ala Val Arg
1 5
<210> 359
<211> 17
<212> PRT
<213> Homo sapiens
<400> 359
Ala Pro Glu Pro His Val Glu Glu Asp Asp Asp Asp Glu Leu Asp Ser
1 5 10 15
Lys
<210> 360
<211> 25
<212> PRT
<213> Homo sapiens
<400> 360
Ala Pro Glu Pro Ile Ser Thr Gln Ser His Ser Val Leu Ile Leu Phe
1 5 10 15
His Ser Asp Asn Ser Gly Glu Asn Arg
20 25
<210> 361
<211> 6
<212> PRT
<213> Homo sapiens
<400> 361
Ala Pro Gly Ala Leu Arg
1 5
<210> 362
<211> 15
<212> PRT
<213> Homo sapiens
<400> 362
Ala Pro Gly Glu Leu Glu His Gly Leu Ile Thr Phe Ser Thr Arg
1 5 10 15
<210> 363
<211> 9
<212> PRT
<213> Homo sapiens
<400> 363
Ala Pro Leu Pro Leu Gly His Ile Lys
1 5
<210> 364
<211> 8
<212> PRT
<213> Homo sapiens
<400> 364
Ala Pro Leu Thr Lys Pro Leu Lys
1 5
<210> 365
<211> 5
<212> PRT
<213> Homo sapiens
<400> 365
Ala Pro Leu Val Lys
1 5
<210> 366
<211> 9
<212> PRT
<213> Homo sapiens
<400> 366
Ala Pro Asn His Ala Val Val Thr Arg
1 5
<210> 367
<211> 8
<212> PRT
<213> Homo sapiens
<400> 367
Ala Pro Asn Val Val Val Thr Arg
1 5
<210> 368
<211> 15
<212> PRT
<213> Homo sapiens
<400> 368
Ala Pro Ser His Gln Gln Ala Thr Thr Ala Gly Ser Pro Leu Arg
1 5 10 15
<210> 369
<211> 12
<212> PRT
<213> Homo sapiens
<400> 369
Ala Pro Ser Thr Trp Leu Thr Ala Tyr Val Val Lys
1 5 10
<210> 370
<211> 46
<212> PRT
<213> Homo sapiens
<400> 370
Ala Pro Val Gly His Phe Tyr Glu Pro Gln Ala Pro Ser Ala Glu Val
1 5 10 15
Glu Met Thr Ser Tyr Val Leu Leu Ala Tyr Leu Thr Ala Gln Pro Ala
20 25 30
Pro Thr Ser Glu Asp Leu Thr Ser Ala Thr Asn Ile Val Lys
35 40 45
<210> 371
<211> 12
<212> PRT
<213> Homo sapiens
<400> 371
Ala Pro Trp Cys His Thr Thr Asn Ser Gln Val Arg
1 5 10
<210> 372
<211> 6
<212> PRT
<213> Homo sapiens
<400> 372
Ala Pro Tyr Glu Trp Lys
1 5
<210> 373
<211> 17
<212> PRT
<213> Homo sapiens
<400> 373
Ala Pro Tyr Pro Asn Tyr Asp Arg Asp Ile Leu Thr Ile Asp Ile Gly
1 5 10 15
Arg
<210> 374
<211> 21
<212> PRT
<213> Homo sapiens
<400> 374
Ala Gln Glu Gln Gln Ser Leu Ile His Thr Asn Gln Ala Glu Ser His
1 5 10 15
Thr Ala Val Gly Arg
20
<210> 375
<211> 17
<212> PRT
<213> Homo sapiens
<400> 375
Ala Gln Gly Phe Thr Glu Asp Thr Ile Val Phe Leu Pro Gln Thr Asp
1 5 10 15
Lys
<210> 376
<211> 10
<212> PRT
<213> Homo sapiens
<400> 376
Ala Gln Gly Tyr Ser Gly Leu Ser Val Lys
1 5 10
<210> 377
<211> 20
<212> PRT
<213> Homo sapiens
<400> 377
Ala Gln His Val Phe Gln His Ala Val Pro Gln Glu Gly Lys Pro Ile
1 5 10 15
Thr Asn Gln Lys
20
<210> 378
<211> 9
<212> PRT
<213> Homo sapiens
<400> 378
Ala Gln Ile His Gly Gly Ile Leu Arg
1 5
<210> 379
<211> 15
<212> PRT
<213> Homo sapiens
<400> 379
Ala Gln Ile Ile Asn Asp Ala Phe Asn Leu Ala Ser Ala His Lys
1 5 10 15
<210> 380
<211> 7
<212> PRT
<213> Homo sapiens
<400> 380
Ala Gln Ile Leu Pro Ile Arg
1 5
<210> 381
<211> 7
<212> PRT
<213> Homo sapiens
<400> 381
Ala Gln Ile Pro Ile Leu Arg
1 5
<210> 382
<211> 7
<212> PRT
<213> Homo sapiens
<400> 382
Ala Gln Ile Ser Ala Tyr Arg
1 5
<210> 383
<211> 7
<212> PRT
<213> Homo sapiens
<400> 383
Ala Gln Ile Thr Gly Tyr Arg
1 5
<210> 384
<211> 13
<212> PRT
<213> Homo sapiens
<400> 384
Ala Gln Leu Gly Asp Leu Pro Trp Gln Val Ala Ile Lys
1 5 10
<210> 385
<211> 7
<212> PRT
<213> Homo sapiens
<400> 385
Ala Gln Leu Val Asp Met Lys
1 5
<210> 386
<211> 8
<212> PRT
<213> Homo sapiens
<400> 386
Ala Gln Leu Val Asp Met Lys Arg
1 5
<210> 387
<211> 24
<212> PRT
<213> Homo sapiens
<400> 387
Ala Gln Leu Val Pro Leu Pro Pro Ser Thr Tyr Val Glu Phe Thr Val
1 5 10 15
Ser Gly Thr Asp Cys Val Ala Lys
20
<210> 388
<211> 21
<212> PRT
<213> Homo sapiens
<400> 388
Ala Gln Asn Leu Tyr Gln Glu Leu Leu Thr Gln Glu Gly Gln Ala Ser
1 5 10 15
Phe Gln Gly Leu Lys
20
<210> 389
<211> 10
<212> PRT
<213> Homo sapiens
<400> 389
Ala Gln Pro Val Gln Ser Lys Pro Gln Lys
1 5 10
<210> 390
<211> 22
<212> PRT
<213> Homo sapiens
<400> 390
Ala Gln Pro Val Gln Val Ala Glu Gly Ser Glu Pro Asp Gly Phe Trp
1 5 10 15
Glu Ala Leu Gly Gly Lys
20
<210> 391
<211> 10
<212> PRT
<213> Homo sapiens
<400> 391
Ala Gln Gln Glu Leu Glu Glu Gln Thr Arg
1 5 10
<210> 392
<211> 14
<212> PRT
<213> Homo sapiens
<400> 392
Ala Gln Gln Val Ser Gln Gly Leu Asp Val Leu Thr Ala Lys
1 5 10
<210> 393
<211> 9
<212> PRT
<213> Homo sapiens
<400> 393
Ala Gln Ser Ile Ala Tyr His Leu Lys
1 5
<210> 394
<211> 14
<212> PRT
<213> Homo sapiens
<400> 394
Ala Gln Val Ser Pro Thr Ala Ser Asp Met Leu His Met Arg
1 5 10
<210> 395
<211> 11
<212> PRT
<213> Homo sapiens
<400> 395
Ala Gln Trp Ala Asn Pro Phe Asp Pro Ser Lys
1 5 10
<210> 396
<211> 22
<212> PRT
<213> Homo sapiens
<400> 396
Ala Gln Trp Ala Asn Pro Phe Asp Pro Ser Lys Thr Glu Asp Ser Ser
1 5 10 15
Ser Phe Leu Ile Asp Lys
20
<210> 397
<211> 9
<212> PRT
<213> Homo sapiens
<400> 397
Ala Gln Tyr Glu Asp Ile Ala Gln Lys
1 5
<210> 398
<211> 9
<212> PRT
<213> Homo sapiens
<400> 398
Ala Gln Tyr Glu Glu Ile Ala Gln Arg
1 5
<210> 399
<211> 13
<212> PRT
<213> Homo sapiens
<400> 399
Ala Gln Tyr Val Leu Ile Ser Pro Glu Ala Ser Ser Arg
1 5 10
<210> 400
<211> 11
<212> PRT
<213> Homo sapiens
<400> 400
Ala Arg Glu Asp Ile Phe Met Glu Thr Leu Lys
1 5 10
<210> 401
<211> 6
<212> PRT
<213> Homo sapiens
<400> 401
Ala Arg Phe Asn Phe Lys
1 5
<210> 402
<211> 9
<212> PRT
<213> Homo sapiens
<400> 402
Ala Arg Ile Gln Glu Ala Val Tyr Lys
1 5
<210> 403
<211> 9
<212> PRT
<213> Homo sapiens
<400> 403
Ala Arg Leu His Glu Ile Leu Gln Lys
1 5
<210> 404
<211> 12
<212> PRT
<213> Homo sapiens
<400> 404
Ala Arg Pro Glu Asp Val Val Asn Leu Asp Leu Lys
1 5 10
<210> 405
<211> 7
<212> PRT
<213> Homo sapiens
<400> 405
Ala Arg Gln Leu Leu Gly Arg
1 5
<210> 406
<211> 22
<212> PRT
<213> Homo sapiens
<400> 406
Ala Ser Ala Gly Leu Leu Gly Ala His Ala Ala Ala Ile Thr Ala Tyr
1 5 10 15
Ala Leu Thr Leu Thr Lys
20
<210> 407
<211> 28
<212> PRT
<213> Homo sapiens
<400> 407
Ala Ser Ala Gly Leu Leu Gly Ala His Ala Ala Ala Ile Thr Ala Tyr
1 5 10 15
Ala Leu Thr Leu Thr Lys Ala Pro Ala Asp Leu Arg
20 25
<210> 408
<211> 25
<212> PRT
<213> Homo sapiens
<400> 408
Ala Ser Ala Ser Tyr Tyr Glu Gln Tyr His Ser Leu Asn Glu Ile Tyr
1 5 10 15
Ser Trp Ile Glu Phe Ile Thr Glu Arg
20 25
<210> 409
<211> 32
<212> PRT
<213> Homo sapiens
<400> 409
Ala Ser Ala Ser Tyr Tyr Glu Gln Tyr His Ser Leu Asn Glu Ile Tyr
1 5 10 15
Ser Trp Ile Glu Phe Ile Thr Glu Arg His Pro Asp Met Leu Thr Lys
20 25 30
<210> 410
<211> 7
<212> PRT
<213> Homo sapiens
<400> 410
Ala Ser Asp Asn Leu Val Lys
1 5
<210> 411
<211> 11
<212> PRT
<213> Homo sapiens
<400> 411
Ala Ser Glu Phe Leu Gly Tyr Trp Glu Pro Arg
1 5 10
<210> 412
<211> 19
<212> PRT
<213> Homo sapiens
<400> 412
Ala Ser Gly Ser Leu Pro Tyr Thr Gln Thr Leu Gln Asp His Leu Asn
1 5 10 15
Ser Leu Lys
<210> 413
<211> 12
<212> PRT
<213> Homo sapiens
<400> 413
Ala Ser His Glu Glu Val Glu Gly Leu Val Glu Lys
1 5 10
<210> 414
<211> 8
<212> PRT
<213> Homo sapiens
<400> 414
Ala Ser His Leu Gly Leu Ala Arg
1 5
<210> 415
<211> 13
<212> PRT
<213> Homo sapiens
<400> 415
Ala Ser His Thr Ala Pro Gln Val Leu Phe Ser His Arg
1 5 10
<210> 416
<211> 20
<212> PRT
<213> Homo sapiens
<400> 416
Ala Ser His Thr Ala Pro Gln Val Leu Phe Ser His Arg Glu Pro Pro
1 5 10 15
Leu Glu Leu Lys
20
<210> 417
<211> 11
<212> PRT
<213> Homo sapiens
<400> 417
Ala Ser Ile His Glu Ala Trp Thr Asp Gly Lys
1 5 10
<210> 418
<211> 6
<212> PRT
<213> Homo sapiens
<400> 418
Ala Ser Ile Ile Thr Lys
1 5
<210> 419
<211> 7
<212> PRT
<213> Homo sapiens
<400> 419
Ala Ser Ile Gln Tyr Ser Lys
1 5
<210> 420
<211> 18
<212> PRT
<213> Homo sapiens
<400> 420
Ala Ser Lys Pro Gly Trp Trp Leu Leu Asn Thr Glu Val Gly Glu Asn
1 5 10 15
Gln Arg
<210> 421
<211> 5
<212> PRT
<213> Homo sapiens
<400> 421
Ala Ser Leu Gln Lys
1 5
<210> 422
<211> 13
<212> PRT
<213> Homo sapiens
<400> 422
Ala Ser Met His Pro Val Thr Ala Met Leu Val Gly Lys
1 5 10
<210> 423
<211> 17
<212> PRT
<213> Homo sapiens
<400> 423
Ala Ser Gln His Gly Ser Asp Val Val Ile Glu Thr Asp Phe Gly Leu
1 5 10 15
Arg
<210> 424
<211> 21
<212> PRT
<213> Homo sapiens
<400> 424
Ala Ser Gln Ser Val Ser Ser Tyr Leu Ala Trp Tyr Gln Gln Lys Pro
1 5 10 15
Gly Gln Ala Pro Arg
20
<210> 425
<211> 18
<212> PRT
<213> Homo sapiens
<400> 425
Ala Ser Ser Glu Gly Gly Thr Ala Ala Gly Ala Gly Leu Asp Ser Leu
1 5 10 15
His Lys
<210> 426
<211> 8
<212> PRT
<213> Homo sapiens
<400> 426
Ala Ser Ser Phe Leu Gly Glu Lys
1 5
<210> 427
<211> 12
<212> PRT
<213> Homo sapiens
<400> 427
Ala Ser Ser Ile Ile Asp Glu Leu Phe Gln Asp Arg
1 5 10
<210> 428
<211> 10
<212> PRT
<213> Homo sapiens
<400> 428
Ala Ser Ser Leu Ile Glu Glu Ala Lys Lys
1 5 10
<210> 429
<211> 18
<212> PRT
<213> Homo sapiens
<400> 429
Ala Ser Ser Gln Trp Val Val Gly Pro Ser Tyr Phe Val Glu Tyr Leu
1 5 10 15
Ile Lys
<210> 430
<211> 12
<212> PRT
<213> Homo sapiens
<400> 430
Ala Ser Ser Val Val Val Ser Gly Thr Pro Ile Arg
1 5 10
<210> 431
<211> 17
<212> PRT
<213> Homo sapiens
<400> 431
Ala Ser Thr Pro Asn Gly Tyr Asp Asn Gly Ile Ile Trp Ala Thr Trp
1 5 10 15
Lys
<210> 432
<211> 19
<212> PRT
<213> Homo sapiens
<400> 432
Ala Ser Thr Pro Asn Gly Tyr Asp Asn Gly Ile Ile Trp Ala Thr Trp
1 5 10 15
Lys Thr Arg
<210> 433
<211> 11
<212> PRT
<213> Homo sapiens
<400> 433
Ala Ser Val Gly Gln Asp Ser Pro Glu Pro Arg
1 5 10
<210> 434
<211> 16
<212> PRT
<213> Homo sapiens
<400> 434
Ala Ser Val Gln Leu Leu Val Gln Asp Ser Leu Asn Pro Ala Val Lys
1 5 10 15
<210> 435
<211> 11
<212> PRT
<213> Homo sapiens
<400> 435
Ala Ser Tyr Ala Gln Gln Pro Ala Glu Ser Arg
1 5 10
<210> 436
<211> 8
<212> PRT
<213> Homo sapiens
<400> 436
Ala Ser Tyr Leu Asp Cys Ile Arg
1 5
<210> 437
<211> 10
<212> PRT
<213> Homo sapiens
<400> 437
Ala Ser Tyr Pro Asp Ile Thr Gly Glu Lys
1 5 10
<210> 438
<211> 13
<212> PRT
<213> Homo sapiens
<400> 438
Ala Thr Ala Pro Gln Thr Gln His Val Ser Pro Met Arg
1 5 10
<210> 439
<211> 11
<212> PRT
<213> Homo sapiens
<400> 439
Ala Thr Ala Gln Met Leu Glu Val Met Phe Lys
1 5 10
<210> 440
<211> 17
<212> PRT
<213> Homo sapiens
<400> 440
Ala Thr Ala Gln Met Leu Glu Val Met Phe Lys Gly Glu Ile Phe His
1 5 10 15
Arg
<210> 441
<211> 10
<212> PRT
<213> Homo sapiens
<400> 441
Ala Thr Ala Val Val Asp Gly Ala Phe Lys
1 5 10
<210> 442
<211> 10
<212> PRT
<213> Homo sapiens
<400> 442
Ala Thr Glu Asp Glu Gly Ser Glu Gln Lys
1 5 10
<210> 443
<211> 17
<212> PRT
<213> Homo sapiens
<400> 443
Ala Thr Glu Asp Glu Gly Ser Glu Gln Lys Ile Pro Glu Ala Thr Asn
1 5 10 15
Arg
<210> 444
<211> 11
<212> PRT
<213> Homo sapiens
<400> 444
Ala Thr Glu His Leu Ser Thr Leu Ser Glu Lys
1 5 10
<210> 445
<211> 21
<212> PRT
<213> Homo sapiens
<400> 445
Ala Thr Phe Gly Cys His Asp Gly Tyr Ser Leu Asp Gly Pro Glu Glu
1 5 10 15
Ile Glu Cys Thr Lys
20
<210> 446
<211> 26
<212> PRT
<213> Homo sapiens
<400> 446
Ala Thr Phe Met Val Gly Ser Tyr Gly Pro Arg Pro Glu Glu Tyr Glu
1 5 10 15
Phe Leu Thr Pro Val Glu Glu Ala Pro Lys
20 25
<210> 447
<211> 9
<212> PRT
<213> Homo sapiens
<400> 447
Ala Thr Phe Asn Pro Ala Gln Asp Lys
1 5
<210> 448
<211> 7
<212> PRT
<213> Homo sapiens
<400> 448
Ala Thr Gly Ile Pro Ala Arg
1 5
<210> 449
<211> 11
<212> PRT
<213> Homo sapiens
<400> 449
Ala Thr Gly Val Leu Tyr Asp Tyr Val Asn Lys
1 5 10
<210> 450
<211> 22
<212> PRT
<213> Homo sapiens
<400> 450
Ala Thr Gly Val Leu Tyr Asp Tyr Val Asn Lys Tyr His Trp Glu His
1 5 10 15
Thr Gly Leu Thr Leu Arg
20
<210> 451
<211> 9
<212> PRT
<213> Homo sapiens
<400> 451
Ala Thr His Gly Gly Leu Gly Leu Arg
1 5
<210> 452
<211> 15
<212> PRT
<213> Homo sapiens
<400> 452
Ala Thr Ile Ser His Val Ser Pro Asp Ser Leu Tyr Leu Phe Arg
1 5 10 15
<210> 453
<211> 7
<212> PRT
<213> Homo sapiens
<400> 453
Ala Thr Ile Thr Gly Tyr Arg
1 5
<210> 454
<211> 21
<212> PRT
<213> Homo sapiens
<400> 454
Ala Thr Leu Asp Val Asp Glu Ala Gly Thr Glu Ala Ala Ala Ala Thr
1 5 10 15
Ser Phe Ala Ile Lys
20
<210> 455
<211> 29
<212> PRT
<213> Homo sapiens
<400> 455
Ala Thr Leu Asp Val Asp Glu Ala Gly Thr Glu Ala Ala Ala Ala Thr
1 5 10 15
Ser Phe Ala Ile Lys Phe Phe Ser Ala Gln Thr Asn Arg
20 25
<210> 456
<211> 14
<212> PRT
<213> Homo sapiens
<400> 456
Ala Thr Leu Gly Pro Ala Val Arg Pro Leu Pro Trp Gln Arg
1 5 10
<210> 457
<211> 8
<212> PRT
<213> Homo sapiens
<400> 457
Ala Thr Leu Leu Asp Ile Tyr Lys
1 5
<210> 458
<211> 10
<212> PRT
<213> Homo sapiens
<400> 458
Ala Thr Leu Pro Asp Ala Asp Lys Glu Arg
1 5 10
<210> 459
<211> 6
<212> PRT
<213> Homo sapiens
<400> 459
Ala Thr Leu Ser Cys Arg
1 5
<210> 460
<211> 6
<212> PRT
<213> Homo sapiens
<400> 460
Ala Thr Leu Ser Glu Lys
1 5
<210> 461
<211> 20
<212> PRT
<213> Homo sapiens
<400> 461
Ala Thr Leu Val Cys Leu Ile Ser Asp Phe Tyr Pro Gly Ala Val Thr
1 5 10 15
Val Ala Trp Lys
20
<210> 462
<211> 15
<212> PRT
<213> Homo sapiens
<400> 462
Ala Thr Leu Tyr Ala Leu Ser His Ala Val Asn Asn Tyr His Lys
1 5 10 15
<210> 463
<211> 19
<212> PRT
<213> Homo sapiens
<400> 463
Ala Thr Thr Val Thr Gly Thr Pro Cys Gln Asp Trp Ala Ala Gln Glu
1 5 10 15
Pro His Arg
<210> 464
<211> 14
<212> PRT
<213> Homo sapiens
<400> 464
Ala Thr Val Ala Val Tyr Leu Glu Ser Leu Gln Asp Thr Lys
1 5 10
<210> 465
<211> 9
<212> PRT
<213> Homo sapiens
<400> 465
Ala Thr Val Leu Asn Tyr Leu Pro Lys
1 5
<210> 466
<211> 12
<212> PRT
<213> Homo sapiens
<400> 466
Ala Thr Val Leu Asn Tyr Leu Pro Lys Cys Ile Arg
1 5 10
<210> 467
<211> 9
<212> PRT
<213> Homo sapiens
<400> 467
Ala Thr Val Asn Pro Ser Ala Pro Arg
1 5
<210> 468
<211> 9
<212> PRT
<213> Homo sapiens
<400> 468
Ala Thr Val Val Glu Ser Ser Glu Lys
1 5
<210> 469
<211> 9
<212> PRT
<213> Homo sapiens
<400> 469
Ala Thr Val Val Tyr Gln Gly Glu Arg
1 5
<210> 470
<211> 11
<212> PRT
<213> Homo sapiens
<400> 470
Ala Thr Trp Ser Gly Ala Val Leu Ala Gly Arg
1 5 10
<210> 471
<211> 8
<212> PRT
<213> Homo sapiens
<400> 471
Ala Thr Tyr Ile Gln Asn Tyr Arg
1 5
<210> 472
<211> 11
<212> PRT
<213> Homo sapiens
<400> 472
Ala Thr Tyr Thr Ile Ser Ile Thr His Pro Lys
1 5 10
<210> 473
<211> 10
<212> PRT
<213> Homo sapiens
<400> 473
Ala Val Ala Glu Pro Gly Ile Gln Leu Lys
1 5 10
<210> 474
<211> 13
<212> PRT
<213> Homo sapiens
<400> 474
Ala Val Ala Gly Asn Ile Ser Asp Pro Gly Leu Gln Lys
1 5 10
<210> 475
<211> 9
<212> PRT
<213> Homo sapiens
<400> 475
Ala Val Ala Asn Ser Arg Pro Ala Lys
1 5
<210> 476
<211> 7
<212> PRT
<213> Homo sapiens
<400> 476
Ala Val Ala Ser Phe Leu Arg
1 5
<210> 477
<211> 7
<212> PRT
<213> Homo sapiens
<400> 477
Ala Val Asp Ala Ala Leu Lys
1 5
<210> 478
<211> 8
<212> PRT
<213> Homo sapiens
<400> 478
Ala Val Asp Ala Ala Leu Lys Lys
1 5
<210> 479
<211> 8
<212> PRT
<213> Homo sapiens
<400> 479
Ala Val Asp Ala Leu Val Lys Lys
1 5
<210> 480
<211> 27
<212> PRT
<213> Homo sapiens
<400> 480
Ala Val Asp Gln Ser Val Leu Leu Met Lys Pro Asp Ala Glu Leu Ser
1 5 10 15
Ala Ser Ser Val Tyr Asn Leu Leu Pro Glu Lys
20 25
<210> 481
<211> 47
<212> PRT
<213> Homo sapiens
<400> 481
Ala Val Asp Gln Ser Val Leu Leu Met Lys Pro Asp Ala Glu Leu Ser
1 5 10 15
Ala Ser Ser Val Tyr Asn Leu Leu Pro Glu Lys Asp Leu Thr Gly Phe
20 25 30
Pro Gly Pro Leu Asn Asp Gln Asp Asp Glu Asp Cys Ile Asn Arg
35 40 45
<210> 482
<211> 27
<212> PRT
<213> Homo sapiens
<400> 482
Ala Val Asp Gln Ser Val Leu Leu Met Lys Pro Glu Ala Glu Leu Ser
1 5 10 15
Val Ser Ser Val Tyr Asn Leu Leu Thr Val Lys
20 25
<210> 483
<211> 10
<212> PRT
<213> Homo sapiens
<400> 483
Ala Val Asp Thr Trp Ser Trp Gly Glu Arg
1 5 10
<210> 484
<211> 7
<212> PRT
<213> Homo sapiens
<400> 484
Ala Val Glu His Ile Asn Lys
1 5
<210> 485
<211> 7
<212> PRT
<213> Homo sapiens
<400> 485
Ala Val Glu Ile Gly Val Lys
1 5
<210> 486
<211> 7
<212> PRT
<213> Homo sapiens
<400> 486
Ala Val Glu Leu Gly Val Lys
1 5
<210> 487
<211> 11
<212> PRT
<213> Homo sapiens
<400> 487
Ala Val Glu Pro Gln Leu Gln Glu Glu Glu Arg
1 5 10
<210> 488
<211> 7
<212> PRT
<213> Homo sapiens
<400> 488
Ala Val Glu Val Leu Pro Lys
1 5
<210> 489
<211> 11
<212> PRT
<213> Homo sapiens
<400> 489
Ala Val Phe Pro Ser Ile Val Gly Arg Pro Arg
1 5 10
<210> 490
<211> 8
<212> PRT
<213> Homo sapiens
<400> 490
Ala Val Phe Val Ser Glu Gly Lys
1 5
<210> 491
<211> 10
<212> PRT
<213> Homo sapiens
<400> 491
Ala Val Gly Glu Glu Val Trp His Ser Lys
1 5 10
<210> 492
<211> 9
<212> PRT
<213> Homo sapiens
<400> 492
Ala Val Gly Leu Ala Gly Thr Phe Arg
1 5
<210> 493
<211> 6
<212> PRT
<213> Homo sapiens
<400> 493
Ala Val Gly Asn Leu Arg
1 5
<210> 494
<211> 18
<212> PRT
<213> Homo sapiens
<400> 494
Ala Val Gly Ser Gly Ala Thr Phe Ser His Tyr Tyr Tyr Met Ile Leu
1 5 10 15
Ser Arg
<210> 495
<211> 11
<212> PRT
<213> Homo sapiens
<400> 495
Ala Val Gly Tyr Leu Ile Thr Gly Tyr Gln Arg
1 5 10
<210> 496
<211> 12
<212> PRT
<213> Homo sapiens
<400> 496
Ala Val His Lys Ala Val Leu Thr Ile Asp Glu Lys
1 5 10
<210> 497
<211> 12
<212> PRT
<213> Homo sapiens
<400> 497
Ala Val Ile Ser Pro Gly Phe Asp Val Phe Ala Lys
1 5 10
<210> 498
<211> 10
<212> PRT
<213> Homo sapiens
<400> 498
Ala Val Ile Thr Val Gln Arg Pro Gly Arg
1 5 10
<210> 499
<211> 19
<212> PRT
<213> Homo sapiens
<400> 499
Ala Val Leu Asp Val Phe Glu Glu Gly Thr Glu Ala Ser Ala Ala Thr
1 5 10 15
Ala Val Lys
<210> 500
<211> 30
<212> PRT
<213> Homo sapiens
<400> 500
Ala Val Leu Asp Val Phe Glu Glu Gly Thr Glu Ala Ser Ala Ala Thr
1 5 10 15
Ala Val Lys Ile Thr Leu Leu Ser Ala Leu Val Glu Thr Arg
20 25 30
<210> 501
<211> 8
<212> PRT
<213> Homo sapiens
<400> 501
Ala Val Leu His Ile Gly Glu Lys
1 5
<210> 502
<211> 8
<212> PRT
<213> Homo sapiens
<400> 502
Ala Val Leu His Val Ala Leu Arg
1 5
<210> 503
<211> 30
<212> PRT
<213> Homo sapiens
<400> 503
Ala Val Leu Gln Leu Asn Glu Glu Gly Val Asp Thr Ala Gly Ser Thr
1 5 10 15
Gly Val Thr Leu Asn Leu Thr Ser Lys Pro Ile Ile Leu Arg
20 25 30
<210> 504
<211> 7
<212> PRT
<213> Homo sapiens
<400> 504
Ala Val Leu Gln Asn Leu Lys
1 5
<210> 505
<211> 8
<212> PRT
<213> Homo sapiens
<400> 505
Ala Val Leu Thr Ile Asp Glu Lys
1 5
<210> 506
<211> 30
<212> PRT
<213> Homo sapiens
<400> 506
Ala Val Leu Thr Ile Asp Glu Lys Gly Thr Glu Ala Ala Gly Ala Met
1 5 10 15
Phe Leu Glu Ala Ile Pro Met Ser Ile Pro Pro Glu Val Lys
20 25 30
<210> 507
<211> 6
<212> PRT
<213> Homo sapiens
<400> 507
Ala Val Leu Thr Gln Lys
1 5
<210> 508
<211> 7
<212> PRT
<213> Homo sapiens
<400> 508
Ala Val Leu Tyr Asn Tyr Arg
1 5
<210> 509
<211> 12
<212> PRT
<213> Homo sapiens
<400> 509
Ala Val Met Asp Asp Phe Ala Ala Phe Val Glu Lys
1 5 10
<210> 510
<211> 17
<212> PRT
<213> Homo sapiens
<400> 510
Ala Val Met Gly Ala Met Lys Pro Gly Val Trp Trp Pro Asp Met His
1 5 10 15
Arg
<210> 511
<211> 24
<212> PRT
<213> Homo sapiens
<400> 511
Ala Val Pro His Pro Asp Ser Gln Pro Asp Thr Ile Asp His Asp Leu
1 5 10 15
Leu Leu Leu Gln Leu Ser Glu Lys
20
<210> 512
<211> 9
<212> PRT
<213> Homo sapiens
<400> 512
Ala Val Gln Ala Asp Gly Gln Val Lys
1 5
<210> 513
<211> 14
<212> PRT
<213> Homo sapiens
<400> 513
Ala Val Gln Gly Phe His Thr Gly Val His Gln Ala Gly Lys
1 5 10
<210> 514
<211> 7
<212> PRT
<213> Homo sapiens
<400> 514
Ala Val Gln Leu Ala Glu Lys
1 5
<210> 515
<211> 11
<212> PRT
<213> Homo sapiens
<400> 515
Ala Val Gln Pro Gly Glu Thr Tyr Thr Tyr Lys
1 5 10
<210> 516
<211> 16
<212> PRT
<213> Homo sapiens
<400> 516
Ala Val Gln Gln Pro Asp Gly Leu Ala Val Leu Gly Ile Phe Leu Lys
1 5 10 15
<210> 517
<211> 7
<212> PRT
<213> Homo sapiens
<400> 517
Ala Val Gln Ser Leu Asp Lys
1 5
<210> 518
<211> 8
<212> PRT
<213> Homo sapiens
<400> 518
Ala Val Arg Pro Gly Tyr Pro Lys
1 5
<210> 519
<211> 9
<212> PRT
<213> Homo sapiens
<400> 519
Ala Val Ser Pro Leu Pro Tyr Leu Arg
1 5
<210> 520
<211> 14
<212> PRT
<213> Homo sapiens
<400> 520
Ala Val Ser Thr Gly Gly Gly Gly His Val Gln Leu Leu Arg
1 5 10
<210> 521
<211> 14
<212> PRT
<213> Homo sapiens
<400> 521
Ala Val Thr Glu Gln Gly His Glu Leu Ser Asn Glu Glu Arg
1 5 10
<210> 522
<211> 11
<212> PRT
<213> Homo sapiens
<400> 522
Ala Val Val Phe Leu Glu Pro Gln Trp Tyr Arg
1 5 10
<210> 523
<211> 15
<212> PRT
<213> Homo sapiens
<400> 523
Ala Val Val Phe Leu Glu Pro Gln Trp Tyr Ser Val Leu Glu Lys
1 5 10 15
<210> 524
<211> 13
<212> PRT
<213> Homo sapiens
<400> 524
Ala Val Val Val His Ala Gly Glu Asp Asp Leu Gly Arg
1 5 10
<210> 525
<211> 8
<212> PRT
<213> Homo sapiens
<400> 525
Ala Val Tyr Glu Ala Val Leu Arg
1 5
<210> 526
<211> 18
<212> PRT
<213> Homo sapiens
<400> 526
Ala Val Tyr Thr Cys Asn Glu Gly Tyr Gln Leu Leu Gly Glu Ile Asn
1 5 10 15
Tyr Arg
<210> 527
<211> 6
<212> PRT
<213> Homo sapiens
<400> 527
Ala Trp Ala Val Ala Arg
1 5
<210> 528
<211> 8
<212> PRT
<213> Homo sapiens
<400> 528
Ala Trp Glu Asp Thr Leu Asp Lys
1 5
<210> 529
<211> 7
<212> PRT
<213> Homo sapiens
<400> 529
Ala Trp Phe Leu Glu Ser Lys
1 5
<210> 530
<211> 14
<212> PRT
<213> Homo sapiens
<400> 530
Ala Trp Gly Glu Ser Thr Pro Leu Ala Asn Lys Pro Gly Lys
1 5 10
<210> 531
<211> 7
<212> PRT
<213> Homo sapiens
<400> 531
Ala Trp Leu Met Ala Ser Arg
1 5
<210> 532
<211> 13
<212> PRT
<213> Homo sapiens
<400> 532
Ala Trp Leu Met Ser Asp Lys Thr Asp Leu Glu Ala Lys
1 5 10
<210> 533
<211> 12
<212> PRT
<213> Homo sapiens
<400> 533
Ala Tyr Phe His Leu Leu Asn Gln Ile Ala Pro Lys
1 5 10
<210> 534
<211> 20
<212> PRT
<213> Homo sapiens
<400> 534
Ala Tyr Ile Phe Ile Asp Glu Ala His Ile Thr Gln Ala Leu Ile Trp
1 5 10 15
Leu Ser Gln Arg
20
<210> 535
<211> 20
<212> PRT
<213> Homo sapiens
<400> 535
Ala Tyr Ile Ser Met His Ser Tyr Ser Gln His Ile Val Phe Pro Tyr
1 5 10 15
Ser Tyr Thr Arg
20
<210> 536
<211> 18
<212> PRT
<213> Homo sapiens
<400> 536
Ala Tyr Lys Ser Glu Leu Glu Glu Gln Leu Thr Pro Val Ala Glu Glu
1 5 10 15
Thr Arg
<210> 537
<211> 12
<212> PRT
<213> Homo sapiens
<400> 537
Ala Tyr Leu Glu Glu Glu Cys Pro Ala Thr Leu Arg
1 5 10
<210> 538
<211> 13
<212> PRT
<213> Homo sapiens
<400> 538
Ala Tyr Leu Glu Glu Glu Cys Pro Ala Thr Leu Arg Lys
1 5 10
<210> 539
<211> 8
<212> PRT
<213> Homo sapiens
<400> 539
Ala Tyr Asn Arg Pro Thr Leu Arg
1 5
<210> 540
<211> 7
<212> PRT
<213> Homo sapiens
<400> 540
Ala Tyr Ser Asp Leu Ser Arg
1 5
<210> 541
<211> 10
<212> PRT
<213> Homo sapiens
<400> 541
Ala Tyr Ser Glu Ala His Glu Ile Ser Lys
1 5 10
<210> 542
<211> 10
<212> PRT
<213> Homo sapiens
<400> 542
Ala Tyr Ser His Ser Val Ser Leu Thr Arg
1 5 10
<210> 543
<211> 12
<212> PRT
<213> Homo sapiens
<400> 543
Ala Tyr Ser Leu Phe Ser Tyr Asn Thr Gln Gly Arg
1 5 10
<210> 544
<211> 20
<212> PRT
<213> Homo sapiens
<400> 544
Ala Tyr Ser Leu Phe Ser Tyr Asn Thr Gln Gly Arg Asp Asn Glu Leu
1 5 10 15
Leu Val Tyr Lys
20
<210> 545
<211> 15
<212> PRT
<213> Homo sapiens
<400> 545
Ala Tyr Trp Asp Ile Met Ile Ser Asn His Gln Asn Ser Asn Arg
1 5 10 15
<210> 546
<211> 18
<212> PRT
<213> Homo sapiens
<400> 546
Ala Tyr Tyr Glu Asn Ser Pro Gln Gln Val Phe Ser Thr Glu Phe Glu
1 5 10 15
Val Lys
<210> 547
<211> 12
<212> PRT
<213> Homo sapiens
<400> 547
Ala Tyr Tyr His Leu Leu Glu Gln Val Ala Pro Lys
1 5 10
<210> 548
<211> 6
<212> PRT
<213> Homo sapiens
<400> 548
Cys Ala Ser Ile Gln Lys
1 5
<210> 549
<211> 6
<212> PRT
<213> Homo sapiens
<400> 549
Cys Ala Ser Leu Gln Lys
1 5
<210> 550
<211> 13
<212> PRT
<213> Homo sapiens
<400> 550
Cys Asp Ser Ser Pro Asp Ser Ala Glu Asp Val Arg Lys
1 5 10
<210> 551
<211> 6
<212> PRT
<213> Homo sapiens
<400> 551
Cys Asp Val Asp Ile Arg
1 5
<210> 552
<211> 6
<212> PRT
<213> Homo sapiens
<400> 552
Cys Glu Pro Leu Glu Lys
1 5
<210> 553
<211> 6
<212> PRT
<213> Homo sapiens
<400> 553
Cys Glu Val Gln Asp Arg
1 5
<210> 554
<211> 15
<212> PRT
<213> Homo sapiens
<400> 554
Cys Phe Asp Glu Thr Arg Tyr Glu Tyr Leu Glu Gly Gly Asp Arg
1 5 10 15
<210> 555
<211> 14
<212> PRT
<213> Homo sapiens
<400> 555
Cys Phe Glu Gly Phe Gly Ile Asp Gly Pro Ala Ile Ala Lys
1 5 10
<210> 556
<211> 9
<212> PRT
<213> Homo sapiens
<400> 556
Cys Phe Leu Ala Phe Thr Gln Thr Lys
1 5
<210> 557
<211> 9
<212> PRT
<213> Homo sapiens
<400> 557
Cys His Ala Ala Asn Pro Asn Gly Arg
1 5
<210> 558
<211> 18
<212> PRT
<213> Homo sapiens
<400> 558
Cys His Ala Gly His Leu Asn Gly Val Tyr Tyr Gln Gly Gly Thr Tyr
1 5 10 15
Ser Lys
<210> 559
<211> 7
<212> PRT
<213> Homo sapiens
<400> 559
Cys Ile Thr Ala Met Ala Lys
1 5
<210> 560
<211> 9
<212> PRT
<213> Homo sapiens
<400> 560
Cys Leu Ala Pro Leu Glu Gly Ala Arg
1 5
<210> 561
<211> 10
<212> PRT
<213> Homo sapiens
<400> 561
Cys Leu Ala Tyr Asp Phe Tyr Pro Gly Lys
1 5 10
<210> 562
<211> 8
<212> PRT
<213> Homo sapiens
<400> 562
Cys Leu Glu Val Glu Gly His Arg
1 5
<210> 563
<211> 9
<212> PRT
<213> Homo sapiens
<400> 563
Cys Leu His Pro Cys Val Ile Ser Arg
1 5
<210> 564
<211> 11
<212> PRT
<213> Homo sapiens
<400> 564
Cys Leu Pro Val Thr Ala Pro Glu Asn Gly Lys
1 5 10
<210> 565
<211> 12
<212> PRT
<213> Homo sapiens
<400> 565
Cys Leu Val Glu Lys Gly Asp Val Ala Phe Val Lys
1 5 10
<210> 566
<211> 8
<212> PRT
<213> Homo sapiens
<400> 566
Cys Leu Val Asn Leu Ile Glu Lys
1 5
<210> 567
<211> 7
<212> PRT
<213> Homo sapiens
<400> 567
Cys Asn Leu Leu Ala Glu Lys
1 5
<210> 568
<211> 10
<212> PRT
<213> Homo sapiens
<400> 568
Cys Asn Met Gly Tyr Glu Tyr Ser Glu Arg
1 5 10
<210> 569
<211> 12
<212> PRT
<213> Homo sapiens
<400> 569
Cys Pro Glu Asp Gln Asp Ala Glu Gly Phe Gln Lys
1 5 10
<210> 570
<211> 23
<212> PRT
<213> Homo sapiens
<400> 570
Cys Pro Phe Pro Ser Arg Pro Asp Asn Gly Phe Val Asn Tyr Pro Ala
1 5 10 15
Lys Pro Thr Leu Tyr Tyr Lys
20
<210> 571
<211> 6
<212> PRT
<213> Homo sapiens
<400> 571
Cys Pro Leu Met Val Lys
1 5
<210> 572
<211> 13
<212> PRT
<213> Homo sapiens
<400> 572
Cys Gln Phe Phe Ser Tyr Ala Thr Gln Thr Phe His Lys
1 5 10
<210> 573
<211> 11
<212> PRT
<213> Homo sapiens
<400> 573
Cys Gln Ser Trp Ser Ser Met Thr Pro His Arg
1 5 10
<210> 574
<211> 28
<212> PRT
<213> Homo sapiens
<400> 574
Cys Ser Pro His Leu Val Leu Ser Ala Leu Thr Ser Asp Asn His Gly
1 5 10 15
Ala Thr Tyr Ala Phe Ser Gly Thr His Tyr Trp Arg
20 25
<210> 575
<211> 8
<212> PRT
<213> Homo sapiens
<400> 575
Cys Thr Asp Ala Val Gly Asp Arg
1 5
<210> 576
<211> 9
<212> PRT
<213> Homo sapiens
<400> 576
Cys Thr Asp Ala Val Gly Asp Arg Arg
1 5
<210> 577
<211> 9
<212> PRT
<213> Homo sapiens
<400> 577
Cys Thr Glu Gly Phe Asn Val Asp Lys
1 5
<210> 578
<211> 10
<212> PRT
<213> Homo sapiens
<400> 578
Cys Thr Glu Gly Phe Asn Val Asp Lys Lys
1 5 10
<210> 579
<211> 11
<212> PRT
<213> Homo sapiens
<400> 579
Cys Thr Ser Thr Gly Trp Ile Pro Ala Pro Arg
1 5 10
<210> 580
<211> 13
<212> PRT
<213> Homo sapiens
<400> 580
Cys Val Gln Ser Thr Lys Pro Ser Leu Met Ile Gln Lys
1 5 10
<210> 581
<211> 16
<212> PRT
<213> Homo sapiens
<400> 581
Cys Tyr Phe Pro Tyr Leu Glu Asn Gly Tyr Asn Gln Asn His Gly Arg
1 5 10 15
<210> 582
<211> 7
<212> PRT
<213> Homo sapiens
<400> 582
Asp Ala Asp Asp Leu Gln Lys
1 5
<210> 583
<211> 10
<212> PRT
<213> Homo sapiens
<400> 583
Asp Ala Asp Pro Asp Thr Phe Phe Ala Lys
1 5 10
<210> 584
<211> 9
<212> PRT
<213> Homo sapiens
<400> 584
Asp Ala Glu Ala Trp Phe Asn Glu Lys
1 5
<210> 585
<211> 6
<212> PRT
<213> Homo sapiens
<400> 585
Asp Ala Glu Glu Ile Lys
1 5
<210> 586
<211> 13
<212> PRT
<213> Homo sapiens
<400> 586
Asp Ala Phe Asp Thr Leu Phe Asp His Ala Pro Asp Lys
1 5 10
<210> 587
<211> 19
<212> PRT
<213> Homo sapiens
<400> 587
Asp Ala Gly Glu Gly Leu Leu Ala Val Gln Ile Thr Asp Pro Glu Gly
1 5 10 15
Lys Pro Lys
<210> 588
<211> 14
<212> PRT
<213> Homo sapiens
<400> 588
Asp Ala His Ser Val Leu Leu Ser His Ile Phe His Gly Arg
1 5 10
<210> 589
<211> 9
<212> PRT
<213> Homo sapiens
<400> 589
Asp Ala Leu Ser Ala Ser Val Val Lys
1 5
<210> 590
<211> 19
<212> PRT
<213> Homo sapiens
<400> 590
Asp Ala Pro Asp His Gln Glu Leu Asn Leu Asp Val Ser Leu Gln Leu
1 5 10 15
Pro Ser Arg
<210> 591
<211> 7
<212> PRT
<213> Homo sapiens
<400> 591
Asp Ala Pro Ile Val Asn Lys
1 5
<210> 592
<211> 35
<212> PRT
<213> Homo sapiens
<400> 592
Asp Ala Pro Ile Val Asn Lys Val Val Thr Pro Leu Ser Pro Pro Thr
1 5 10 15
Asn Leu His Leu Glu Ala Asn Pro Asp Thr Gly Val Leu Thr Val Ser
20 25 30
Trp Glu Arg
35
<210> 593
<211> 12
<212> PRT
<213> Homo sapiens
<400> 593
Asp Ala Gln Glu Val His Cys Asp Glu Ala Thr Lys
1 5 10
<210> 594
<211> 10
<212> PRT
<213> Homo sapiens
<400> 594
Asp Ala Gln Tyr Ala Pro Gly Tyr Asp Lys
1 5 10
<210> 595
<211> 21
<212> PRT
<213> Homo sapiens
<400> 595
Asp Ala Ser Ile Val Gly Phe Phe Asp Asp Ser Phe Ser Glu Ala His
1 5 10 15
Ser Glu Phe Leu Lys
20
<210> 596
<211> 19
<212> PRT
<213> Homo sapiens
<400> 596
Asp Ala Thr Asn Val Gly Asp Glu Gly Gly Phe Ala Pro Asn Ile Leu
1 5 10 15
Glu Asn Lys
<210> 597
<211> 16
<212> PRT
<213> Homo sapiens
<400> 597
Asp Ala Val Glu Lys Pro Gln Glu Phe Thr Ile Val Ala Phe Val Lys
1 5 10 15
<210> 598
<211> 11
<212> PRT
<213> Homo sapiens
<400> 598
Asp Ala Val Leu Met Gln Phe Cys Ala Asn Lys
1 5 10
<210> 599
<211> 5
<212> PRT
<213> Homo sapiens
<400> 599
Asp Ala Val Leu Arg
1 5
<210> 600
<211> 21
<212> PRT
<213> Homo sapiens
<400> 600
Asp Cys Asp Asp Val Leu Gln Thr His Pro Ser Gly Thr Gln Ser Gly
1 5 10 15
Ile Phe Asn Ile Lys
20
<210> 601
<211> 6
<212> PRT
<213> Homo sapiens
<400> 601
Asp Cys Glu Leu Pro Arg
1 5
<210> 602
<211> 15
<212> PRT
<213> Homo sapiens
<400> 602
Asp Cys His Leu Ala Gln Val Pro Ser His Thr Val Val Ala Arg
1 5 10 15
<210> 603
<211> 8
<212> PRT
<213> Homo sapiens
<400> 603
Asp Cys Gln Asp Ile Ala Asn Lys
1 5
<210> 604
<211> 10
<212> PRT
<213> Homo sapiens
<400> 604
Asp Asp Glu Glu Phe Ile Glu Ser Asn Lys
1 5 10
<210> 605
<211> 8
<212> PRT
<213> Homo sapiens
<400> 605
Asp Asp Phe Thr Glu Phe Gly Lys
1 5
<210> 606
<211> 15
<212> PRT
<213> Homo sapiens
<400> 606
Asp Asp Gly Leu Phe Ser Gly Asp Pro Asn Trp Phe Pro Lys Lys
1 5 10 15
<210> 607
<211> 14
<212> PRT
<213> Homo sapiens
<400> 607
Asp Asp Ile Leu Asn Gly Ser His Pro Val Ser Phe Asp Lys
1 5 10
<210> 608
<211> 23
<212> PRT
<213> Homo sapiens
<400> 608
Asp Asp Lys Glu Ser Val Pro Ile Ser Asp Thr Ile Ile Pro Ala Val
1 5 10 15
Pro Pro Pro Thr Asp Leu Arg
20
<210> 609
<211> 18
<212> PRT
<213> Homo sapiens
<400> 609
Asp Asp Lys His Glu Gln Asp Met Val Asn Gly Ile Met Leu Ser Val
1 5 10 15
Glu Lys
<210> 610
<211> 11
<212> PRT
<213> Homo sapiens
<400> 610
Asp Asp Leu Tyr Val Ser Asp Ala Phe His Lys
1 5 10
<210> 611
<211> 8
<212> PRT
<213> Homo sapiens
<400> 611
Asp Asp Asn Pro Asn Leu Pro Arg
1 5
<210> 612
<211> 9
<212> PRT
<213> Homo sapiens
<400> 612
Asp Asp Trp Phe Met Leu Gly Leu Arg
1 5
<210> 613
<211> 6
<212> PRT
<213> Homo sapiens
<400> 613
Asp Glu Cys Phe Ala Arg
1 5
<210> 614
<211> 12
<212> PRT
<213> Homo sapiens
<400> 614
Asp Glu Glu Leu Ser Cys Thr Val Val Glu Leu Lys
1 5 10
<210> 615
<211> 16
<212> PRT
<213> Homo sapiens
<400> 615
Asp Glu Gly Thr Ala Phe Leu Val Tyr Gly Ala Pro Gly Phe Ser Lys
1 5 10 15
<210> 616
<211> 7
<212> PRT
<213> Homo sapiens
<400> 616
Asp Glu Ile Glu Ser Val Lys
1 5
<210> 617
<211> 12
<212> PRT
<213> Homo sapiens
<400> 617
Asp Glu Ile Pro His Asn Asp Ile Ala Leu Leu Lys
1 5 10
<210> 618
<211> 6
<212> PRT
<213> Homo sapiens
<400> 618
Asp Glu Asn Val Leu Lys
1 5
<210> 619
<211> 10
<212> PRT
<213> Homo sapiens
<400> 619
Asp Phe Ala Glu His Leu Leu Ile Pro Arg
1 5 10
<210> 620
<211> 12
<212> PRT
<213> Homo sapiens
<400> 620
Asp Phe Ala Leu Leu Ser Leu Gln Val Pro Leu Lys
1 5 10
<210> 621
<211> 15
<212> PRT
<213> Homo sapiens
<400> 621
Asp Phe Ala Leu Leu Ser Leu Gln Val Pro Leu Lys Asp Ala Lys
1 5 10 15
<210> 622
<211> 10
<212> PRT
<213> Homo sapiens
<400> 622
Asp Phe Asp Phe Val Pro Pro Val Val Arg
1 5 10
<210> 623
<211> 5
<212> PRT
<213> Homo sapiens
<400> 623
Asp Phe Asp Val Lys
1 5
<210> 624
<211> 24
<212> PRT
<213> Homo sapiens
<400> 624
Asp Phe Gly Thr His Tyr Ile Thr Glu Ala Val Leu Gly Gly Ile Tyr
1 5 10 15
Glu Tyr Thr Leu Val Met Asn Lys
20
<210> 625
<211> 29
<212> PRT
<213> Homo sapiens
<400> 625
Asp Phe Gly Thr His Tyr Ile Thr Glu Ala Val Leu Gly Gly Ile Tyr
1 5 10 15
Glu Tyr Thr Leu Val Met Asn Lys Glu Ala Met Glu Arg
20 25
<210> 626
<211> 14
<212> PRT
<213> Homo sapiens
<400> 626
Asp Phe His Ile Asn Leu Phe Gln Val Leu Pro Trp Leu Lys
1 5 10
<210> 627
<211> 8
<212> PRT
<213> Homo sapiens
<400> 627
Asp Phe His Ile Asn Leu Phe Arg
1 5
<210> 628
<211> 15
<212> PRT
<213> Homo sapiens
<400> 628
Asp Phe Ile Ser Leu Gly Leu Gln Asp Gly His Leu Val Phe Arg
1 5 10 15
<210> 629
<211> 12
<212> PRT
<213> Homo sapiens
<400> 629
Asp Phe Leu Gly Phe Tyr Val Val Asp Ser His Arg
1 5 10
<210> 630
<211> 7
<212> PRT
<213> Homo sapiens
<400> 630
Asp Phe Leu Gln Ser Leu Lys
1 5
<210> 631
<211> 6
<212> PRT
<213> Homo sapiens
<400> 631
Asp Phe Pro Ile Ala Lys
1 5
<210> 632
<211> 16
<212> PRT
<213> Homo sapiens
<400> 632
Asp Phe Pro Leu Val Asp Gly His Asn Asp Leu Pro Leu Val Leu Arg
1 5 10 15
<210> 633
<211> 20
<212> PRT
<213> Homo sapiens
<400> 633
Asp Phe Gln Pro Val Leu His Leu Val Ala Leu Asn Ser Pro Leu Ser
1 5 10 15
Gly Gly Met Arg
20
<210> 634
<211> 21
<212> PRT
<213> Homo sapiens
<400> 634
Asp Phe Ser Ala Glu Tyr Glu Glu Asp Gly Lys Tyr Glu Gly Leu Gln
1 5 10 15
Glu Trp Glu Gly Lys
20
<210> 635
<211> 7
<212> PRT
<213> Homo sapiens
<400> 635
Asp Phe Ser Leu Trp Glu Lys
1 5
<210> 636
<211> 6
<212> PRT
<213> Homo sapiens
<400> 636
Asp Phe Thr Ala Tyr Arg
1 5
<210> 637
<211> 10
<212> PRT
<213> Homo sapiens
<400> 637
Asp Phe Thr Cys Val His Gln Ala Leu Lys
1 5 10
<210> 638
<211> 8
<212> PRT
<213> Homo sapiens
<400> 638
Asp Phe Thr Phe Asp Leu Tyr Arg
1 5
<210> 639
<211> 8
<212> PRT
<213> Homo sapiens
<400> 639
Asp Phe Val Gln Pro Pro Thr Lys
1 5
<210> 640
<211> 10
<212> PRT
<213> Homo sapiens
<400> 640
Asp Gly Ala Gly Asp Val Ala Phe Val Lys
1 5 10
<210> 641
<211> 9
<212> PRT
<213> Homo sapiens
<400> 641
Asp Gly Asp Gly Thr Ile Thr Thr Lys
1 5
<210> 642
<211> 13
<212> PRT
<213> Homo sapiens
<400> 642
Asp Gly Glu Gln Ile Glu Gln Glu Glu Asp Asp Glu Lys
1 5 10
<210> 643
<211> 15
<212> PRT
<213> Homo sapiens
<400> 643
Asp Gly Phe Val Gln Asp Glu Gly Thr Met Phe Pro Val Gly Lys
1 5 10 15
<210> 644
<211> 16
<212> PRT
<213> Homo sapiens
<400> 644
Asp Gly His Phe Thr Leu Phe Ala Pro Thr Asn Glu Ala Phe Glu Lys
1 5 10 15
<210> 645
<211> 20
<212> PRT
<213> Homo sapiens
<400> 645
Asp Gly His Val Ile Leu Gln Leu Asn Ser Ile Pro Ser Ser Asp Phe
1 5 10 15
Leu Cys Val Arg
20
<210> 646
<211> 9
<212> PRT
<213> Homo sapiens
<400> 646
Asp Gly Asn Asp His Ser Leu Trp Arg
1 5
<210> 647
<211> 11
<212> PRT
<213> Homo sapiens
<400> 647
Asp Gly Asn Pro Phe Tyr Phe Thr Asp His Arg
1 5 10
<210> 648
<211> 9
<212> PRT
<213> Homo sapiens
<400> 648
Asp Gly Asn Thr Leu Thr Tyr Tyr Arg
1 5
<210> 649
<211> 22
<212> PRT
<213> Homo sapiens
<400> 649
Asp Gly Arg Glu Trp Glu Ile Val Asn Gln Asp Asn His Tyr Ser Pro
1 5 10 15
His Phe Gln Glu Ile Arg
20
<210> 650
<211> 22
<212> PRT
<213> Homo sapiens
<400> 650
Asp Gly Arg Pro Glu Ile Gln Leu His Asn His Trp Ala Gln Leu Thr
1 5 10 15
Val Gly Ala Gly Pro Arg
20
<210> 651
<211> 20
<212> PRT
<213> Homo sapiens
<400> 651
Asp Gly Ser Pro Asp Val Thr Thr Ala Asp Ile Gly Ala Asn Thr Pro
1 5 10 15
Asp Ala Thr Lys
20
<210> 652
<211> 9
<212> PRT
<213> Homo sapiens
<400> 652
Asp Gly Ser Thr Ile Pro Ile Ala Lys
1 5
<210> 653
<211> 13
<212> PRT
<213> Homo sapiens
<400> 653
Asp Gly Thr Phe Leu Asn Leu Val Ser Asp Asp Arg Arg
1 5 10
<210> 654
<211> 16
<212> PRT
<213> Homo sapiens
<400> 654
Asp Gly Thr His Val Val Glu Asn Val Asp Ala Thr His Ile Gly Lys
1 5 10 15
<210> 655
<211> 11
<212> PRT
<213> Homo sapiens
<400> 655
Asp Gly Thr Pro Pro Ile Asp Ala His Thr Arg
1 5 10
<210> 656
<211> 7
<212> PRT
<213> Homo sapiens
<400> 656
Asp Gly Thr Trp Ser Asn Lys
1 5
<210> 657
<211> 28
<212> PRT
<213> Homo sapiens
<400> 657
Asp Gly Trp His Ser Trp Pro Ile Ala His Gln Trp Pro Gln Gly Pro
1 5 10 15
Ser Ala Val Asp Ala Ala Phe Ser Trp Glu Glu Lys
20 25
<210> 658
<211> 11
<212> PRT
<213> Homo sapiens
<400> 658
Asp Gly Trp Ser Ala Gln Pro Thr Cys Ile Lys
1 5 10
<210> 659
<211> 9
<212> PRT
<213> Homo sapiens
<400> 659
Asp Gly Tyr Leu Phe Gln Leu Leu Arg
1 5
<210> 660
<211> 6
<212> PRT
<213> Homo sapiens
<400> 660
Asp Gly Tyr Val Leu Arg
1 5
<210> 661
<211> 9
<212> PRT
<213> Homo sapiens
<400> 661
Asp His Ala Val Asp Leu Ile Gln Lys
1 5
<210> 662
<211> 13
<212> PRT
<213> Homo sapiens
<400> 662
Asp His Ala Val Asp Leu Ile Gln Lys Gly Tyr Met Arg
1 5 10
<210> 663
<211> 14
<212> PRT
<213> Homo sapiens
<400> 663
Asp His Glu Glu Leu Ser Leu Val Ala Ser Glu Ala Val Arg
1 5 10
<210> 664
<211> 9
<212> PRT
<213> Homo sapiens
<400> 664
Asp His Glu Asn Glu Leu Leu Asn Lys
1 5
<210> 665
<211> 20
<212> PRT
<213> Homo sapiens
<400> 665
Asp His His His Pro His Lys Pro His Glu His Gly Pro Pro Pro Pro
1 5 10 15
Pro Asp Glu Arg
20
<210> 666
<211> 14
<212> PRT
<213> Homo sapiens
<400> 666
Asp His Leu Gly Phe Gln Val Thr Trp Pro Asp Glu Ser Lys
1 5 10
<210> 667
<211> 14
<212> PRT
<213> Homo sapiens
<400> 667
Asp His Ser Gly Gln Val Phe Ser Val Val Ser Asn Gly Lys
1 5 10
<210> 668
<211> 10
<212> PRT
<213> Homo sapiens
<400> 668
Asp Ile Ala Ala Asn Glu Glu Asn Arg Lys
1 5 10
<210> 669
<211> 6
<212> PRT
<213> Homo sapiens
<400> 669
Asp Ile Ala Ile Leu Lys
1 5
<210> 670
<211> 6
<212> PRT
<213> Homo sapiens
<400> 670
Asp Ile Ala Leu Leu Lys
1 5
<210> 671
<211> 6
<212> PRT
<213> Homo sapiens
<400> 671
Asp Ile Ala Leu Met Lys
1 5
<210> 672
<211> 12
<212> PRT
<213> Homo sapiens
<400> 672
Asp Ile Ala Pro Thr Leu Thr Leu Tyr Val Gly Lys
1 5 10
<210> 673
<211> 13
<212> PRT
<213> Homo sapiens
<400> 673
Asp Ile Ala Pro Thr Leu Thr Leu Tyr Val Gly Lys Lys
1 5 10
<210> 674
<211> 14
<212> PRT
<213> Homo sapiens
<400> 674
Asp Ile Ala Ser Gly Leu Ile Gly Pro Leu Ile Ile Cys Lys
1 5 10
<210> 675
<211> 15
<212> PRT
<213> Homo sapiens
<400> 675
Asp Ile Ala Ser Gly Leu Ile Gly Pro Leu Ile Ile Cys Lys Lys
1 5 10 15
<210> 676
<211> 9
<212> PRT
<213> Homo sapiens
<400> 676
Asp Ile Ala Trp Thr Glu Asp Ser Lys
1 5
<210> 677
<211> 6
<212> PRT
<213> Homo sapiens
<400> 677
Asp Ile Asp Ser Glu Lys
1 5
<210> 678
<211> 12
<212> PRT
<213> Homo sapiens
<400> 678
Asp Ile Glu Ala Gln Leu Gln His Ala Gly Leu Arg
1 5 10
<210> 679
<211> 12
<212> PRT
<213> Homo sapiens
<400> 679
Asp Ile Glu His Leu Thr Ser Leu Asp Phe Phe Arg
1 5 10
<210> 680
<211> 29
<212> PRT
<213> Homo sapiens
<400> 680
Asp Ile Glu Asn Gln Tyr Glu Thr Gln Ile Thr Gln Ile Glu His Glu
1 5 10 15
Val Ser Ser Ser Gly Gln Glu Val Gln Ser Ser Ala Lys
20 25
<210> 681
<211> 7
<212> PRT
<213> Homo sapiens
<400> 681
Asp Ile Glu Gln Ile Val Lys
1 5
<210> 682
<211> 11
<212> PRT
<213> Homo sapiens
<400> 682
Asp Ile Phe Thr Gly Leu Ile Gly Pro Met Lys
1 5 10
<210> 683
<211> 5
<212> PRT
<213> Homo sapiens
<400> 683
Asp Ile Ile Phe Lys
1 5
<210> 684
<211> 7
<212> PRT
<213> Homo sapiens
<400> 684
Asp Ile Ile Leu Thr Val Lys
1 5
<210> 685
<211> 22
<212> PRT
<213> Homo sapiens
<400> 685
Asp Ile Leu Ala Thr Asn Gly Val Ile His Tyr Ile Asp Glu Leu Leu
1 5 10 15
Ile Pro Asp Ser Ala Lys
20
<210> 686
<211> 5
<212> PRT
<213> Homo sapiens
<400> 686
Asp Ile Leu Asp Arg
1 5
<210> 687
<211> 6
<212> PRT
<213> Homo sapiens
<400> 687
Asp Ile Leu Leu Glu Lys
1 5
<210> 688
<211> 8
<212> PRT
<213> Homo sapiens
<400> 688
Asp Ile Met Ala Glu Ile Tyr Lys
1 5
<210> 689
<211> 5
<212> PRT
<213> Homo sapiens
<400> 689
Asp Ile Met Glu Lys
1 5
<210> 690
<211> 10
<212> PRT
<213> Homo sapiens
<400> 690
Asp Ile Asn Thr Phe Ile His Gly Asn Lys
1 5 10
<210> 691
<211> 11
<212> PRT
<213> Homo sapiens
<400> 691
Asp Ile Asn Thr Phe Ile His Gly Asn Lys Arg
1 5 10
<210> 692
<211> 10
<212> PRT
<213> Homo sapiens
<400> 692
Asp Ile Asn Tyr Val Asn Pro Val Ile Lys
1 5 10
<210> 693
<211> 19
<212> PRT
<213> Homo sapiens
<400> 693
Asp Ile Pro Gln Pro His Ala Glu Pro Trp Ala Phe Ser Leu Asp Leu
1 5 10 15
Gly Leu Lys
<210> 694
<211> 19
<212> PRT
<213> Homo sapiens
<400> 694
Asp Ile Pro Thr Asn Ser Pro Glu Leu Glu Glu Thr Leu Thr His Thr
1 5 10 15
Ile Thr Lys
<210> 695
<211> 6
<212> PRT
<213> Homo sapiens
<400> 695
Asp Ile Gln Asp Leu Lys
1 5
<210> 696
<211> 5
<212> PRT
<213> Homo sapiens
<400> 696
Asp Ile Gln Leu Arg
1 5
<210> 697
<211> 8
<212> PRT
<213> Homo sapiens
<400> 697
Asp Ile Arg Glu Glu Ala Glu Lys
1 5
<210> 698
<211> 9
<212> PRT
<213> Homo sapiens
<400> 698
Asp Ile Ser Glu Val Val Thr Pro Arg
1 5
<210> 699
<211> 21
<212> PRT
<213> Homo sapiens
<400> 699
Asp Ile Thr Asp Thr Leu Val Ala Val Thr Ile Ser Glu Gly Ala His
1 5 10 15
His Leu Asp Leu Arg
20
<210> 700
<211> 18
<212> PRT
<213> Homo sapiens
<400> 700
Asp Ile Val Glu Tyr Tyr Asn Asp Ser Asn Gly Ser His Val Leu Gln
1 5 10 15
Gly Arg
<210> 701
<211> 8
<212> PRT
<213> Homo sapiens
<400> 701
Asp Lys Cys Glu Pro Leu Glu Lys
1 5
<210> 702
<211> 20
<212> PRT
<213> Homo sapiens
<400> 702
Asp Lys Asp Gln Glu Val Leu Leu Gln Thr Phe Leu Asp Asp Ala Ser
1 5 10 15
Pro Gly Asp Lys
20
<210> 703
<211> 11
<212> PRT
<213> Homo sapiens
<400> 703
Asp Lys Glu Pro Leu Thr Ala Tyr Asn Tyr Lys
1 5 10
<210> 704
<211> 10
<212> PRT
<213> Homo sapiens
<400> 704
Asp Lys Ile Gly Val Glu Leu Thr Gly Arg
1 5 10
<210> 705
<211> 6
<212> PRT
<213> Homo sapiens
<400> 705
Asp Lys Pro Leu Val Lys
1 5
<210> 706
<211> 6
<212> PRT
<213> Homo sapiens
<400> 706
Asp Leu Ala Leu Leu Lys
1 5
<210> 707
<211> 11
<212> PRT
<213> Homo sapiens
<400> 707
Asp Leu Ala Thr Val Tyr Val Asp Val Leu Lys
1 5 10
<210> 708
<211> 6
<212> PRT
<213> Homo sapiens
<400> 708
Asp Leu Asp Asp Thr Lys
1 5
<210> 709
<211> 17
<212> PRT
<213> Homo sapiens
<400> 709
Asp Leu Asp Ser Gln Thr Met Met Val Leu Val Asn Tyr Ile Phe Phe
1 5 10 15
Lys
<210> 710
<211> 11
<212> PRT
<213> Homo sapiens
<400> 710
Asp Leu Glu Ala His Ile Asp Ser Ala Asn Lys
1 5 10
<210> 711
<211> 6
<212> PRT
<213> Homo sapiens
<400> 711
Asp Leu Glu Glu Val Lys
1 5
<210> 712
<211> 18
<212> PRT
<213> Homo sapiens
<400> 712
Asp Leu Glu Ile Glu Val Val Leu Phe His Pro Asn Tyr Asn Ile Asn
1 5 10 15
Gly Lys
<210> 713
<211> 19
<212> PRT
<213> Homo sapiens
<400> 713
Asp Leu Glu Ile Glu Val Val Leu Phe His Pro Asn Tyr Asn Ile Asn
1 5 10 15
Gly Lys Lys
<210> 714
<211> 17
<212> PRT
<213> Homo sapiens
<400> 714
Asp Leu Glu Thr Gln Val Ile Gln Leu Asn Glu Gln Val His Ser Leu
1 5 10 15
Lys
<210> 715
<211> 12
<212> PRT
<213> Homo sapiens
<400> 715
Asp Leu Phe His Cys Val Ser Phe Thr Leu Pro Arg
1 5 10
<210> 716
<211> 15
<212> PRT
<213> Homo sapiens
<400> 716
Asp Leu Phe Ile Gly Asp Val Ile His Asn Ala Gly Pro His Arg
1 5 10 15
<210> 717
<211> 8
<212> PRT
<213> Homo sapiens
<400> 717
Asp Leu Gly Glu Glu Asn Phe Lys
1 5
<210> 718
<211> 7
<212> PRT
<213> Homo sapiens
<400> 718
Asp Leu Gly Gln Cys Asp Arg
1 5
<210> 719
<211> 14
<212> PRT
<213> Homo sapiens
<400> 719
Asp Leu His Phe Leu Glu Glu Leu Gln Leu Gly His Asn Arg
1 5 10
<210> 720
<211> 10
<212> PRT
<213> Homo sapiens
<400> 720
Asp Leu His Leu Ser Asp Val Phe Leu Lys
1 5 10
<210> 721
<211> 10
<212> PRT
<213> Homo sapiens
<400> 721
Asp Leu His Pro Asn Thr Asp Pro Phe Lys
1 5 10
<210> 722
<211> 15
<212> PRT
<213> Homo sapiens
<400> 722
Asp Leu His Pro Asn Thr Asp Pro Phe Lys Phe Glu Ile His Lys
1 5 10 15
<210> 723
<211> 5
<212> PRT
<213> Homo sapiens
<400> 723
Asp Leu Ile Phe Lys
1 5
<210> 724
<211> 6
<212> PRT
<213> Homo sapiens
<400> 724
Asp Leu Ile Ser Pro Arg
1 5
<210> 725
<211> 8
<212> PRT
<213> Homo sapiens
<400> 725
Asp Leu Lys Pro Ala Ile Val Lys
1 5
<210> 726
<211> 11
<212> PRT
<213> Homo sapiens
<400> 726
Asp Leu Lys Val Glu Asp Ile Pro Leu Ala Arg
1 5 10
<210> 727
<211> 5
<212> PRT
<213> Homo sapiens
<400> 727
Asp Leu Leu Asp Arg
1 5
<210> 728
<211> 5
<212> PRT
<213> Homo sapiens
<400> 728
Asp Leu Leu Phe Lys
1 5
<210> 729
<211> 13
<212> PRT
<213> Homo sapiens
<400> 729
Asp Leu Leu Phe Lys Asp Ser Ala His Gly Phe Leu Lys
1 5 10
<210> 730
<211> 13
<212> PRT
<213> Homo sapiens
<400> 730
Asp Leu Leu Phe Arg Asp Asp Thr Val Cys Leu Ala Lys
1 5 10
<210> 731
<211> 8
<212> PRT
<213> Homo sapiens
<400> 731
Asp Leu Leu Gly Ile Tyr Glu Lys
1 5
<210> 732
<211> 6
<212> PRT
<213> Homo sapiens
<400> 732
Asp Leu Leu Leu Glu Lys
1 5
<210> 733
<211> 10
<212> PRT
<213> Homo sapiens
<400> 733
Asp Leu Leu Leu Pro Gln Pro Asp Leu Arg
1 5 10
<210> 734
<211> 7
<212> PRT
<213> Homo sapiens
<400> 734
Asp Leu Leu Leu Thr Val Lys
1 5
<210> 735
<211> 9
<212> PRT
<213> Homo sapiens
<400> 735
Asp Leu Leu Asn Asn His Ile Leu Lys
1 5
<210> 736
<211> 6
<212> PRT
<213> Homo sapiens
<400> 736
Asp Leu Leu Pro Ser Arg
1 5
<210> 737
<211> 8
<212> PRT
<213> Homo sapiens
<400> 737
Asp Leu Leu Pro Ser Arg Asp Arg
1 5
<210> 738
<211> 11
<212> PRT
<213> Homo sapiens
<400> 738
Asp Leu Leu Gln Thr Val Glu Asp Gln Tyr Lys
1 5 10
<210> 739
<211> 7
<212> PRT
<213> Homo sapiens
<400> 739
Asp Leu Leu Tyr Ile Gly Lys
1 5
<210> 740
<211> 9
<212> PRT
<213> Homo sapiens
<400> 740
Asp Leu Leu Tyr Ile Gly Lys Asp Arg
1 5
<210> 741
<211> 5
<212> PRT
<213> Homo sapiens
<400> 741
Asp Leu Met Glu Lys
1 5
<210> 742
<211> 6
<212> PRT
<213> Homo sapiens
<400> 742
Asp Leu Gln Glu Val Lys
1 5
<210> 743
<211> 8
<212> PRT
<213> Homo sapiens
<400> 743
Asp Leu Gln Phe Ser Glu Ile Arg
1 5
<210> 744
<211> 11
<212> PRT
<213> Homo sapiens
<400> 744
Asp Leu Gln Phe Val Glu Val Thr Asp Val Lys
1 5 10
<210> 745
<211> 12
<212> PRT
<213> Homo sapiens
<400> 745
Asp Leu Gln Gly Arg Asp Glu Gln Ser Glu Glu Lys
1 5 10
<210> 746
<211> 7
<212> PRT
<213> Homo sapiens
<400> 746
Asp Leu Gln Asn Phe Leu Lys
1 5
<210> 747
<211> 8
<212> PRT
<213> Homo sapiens
<400> 747
Asp Leu Gln Asn Phe Leu Lys Lys
1 5
<210> 748
<211> 15
<212> PRT
<213> Homo sapiens
<400> 748
Asp Leu Gln Ser Leu Glu Asp Ile Leu His Gln Val Glu Asn Lys
1 5 10 15
<210> 749
<211> 20
<212> PRT
<213> Homo sapiens
<400> 749
Asp Leu Gln Ser Leu Glu Asp Ile Leu His Gln Val Glu Asn Lys Thr
1 5 10 15
Ser Glu Val Lys
20
<210> 750
<211> 7
<212> PRT
<213> Homo sapiens
<400> 750
Asp Leu Gln Tyr Val Glu Lys
1 5
<210> 751
<211> 7
<212> PRT
<213> Homo sapiens
<400> 751
Asp Leu Ser Asp Ala Gly Lys
1 5
<210> 752
<211> 10
<212> PRT
<213> Homo sapiens
<400> 752
Asp Leu Ser Leu Leu Gln Ile Gln Met Arg
1 5 10
<210> 753
<211> 8
<212> PRT
<213> Homo sapiens
<400> 753
Asp Leu Thr Asp Tyr Leu Met Lys
1 5
<210> 754
<211> 39
<212> PRT
<213> Homo sapiens
<400> 754
Asp Leu Thr Gly Phe Pro Gly Pro Leu Asn Asp Gln Asp Asp Glu Asp
1 5 10 15
Cys Ile Asn Arg His Asn Val Tyr Ile Asn Gly Ile Thr Tyr Thr Pro
20 25 30
Val Ser Ser Thr Asn Glu Lys
35
<210> 755
<211> 6
<212> PRT
<213> Homo sapiens
<400> 755
Asp Leu Thr Ile Glu Lys
1 5
<210> 756
<211> 32
<212> PRT
<213> Homo sapiens
<400> 756
Asp Leu Thr Ser Leu Gly His Asn Glu Asn Gln Gln Gly Ser Phe Ser
1 5 10 15
Ser Gln Gly Gly Ser Ser Phe Ser Val Pro Ile Phe Tyr Ser Ser Lys
20 25 30
<210> 757
<211> 10
<212> PRT
<213> Homo sapiens
<400> 757
Asp Leu Val Phe Ser Thr Trp Asp His Lys
1 5 10
<210> 758
<211> 5
<212> PRT
<213> Homo sapiens
<400> 758
Asp Leu Trp Gln Lys
1 5
<210> 759
<211> 13
<212> PRT
<213> Homo sapiens
<400> 759
Asp Leu Trp Val Asn Ile Asp Gln Met Glu Lys Asp Lys
1 5 10
<210> 760
<211> 5
<212> PRT
<213> Homo sapiens
<400> 760
Asp Leu Tyr Ser Lys
1 5
<210> 761
<211> 16
<212> PRT
<213> Homo sapiens
<400> 761
Asp Met Ala Leu Thr Ala Phe Val Leu Ile Ser Leu Gln Glu Ala Lys
1 5 10 15
<210> 762
<211> 13
<212> PRT
<213> Homo sapiens
<400> 762
Asp Met Pro Ala Ser Glu Asp Leu Gln Asp Leu Gln Lys
1 5 10
<210> 763
<211> 6
<212> PRT
<213> Homo sapiens
<400> 763
Asp Met Gln Leu Gly Arg
1 5
<210> 764
<211> 15
<212> PRT
<213> Homo sapiens
<400> 764
Asp Met Thr Glu Val Ile Ser Ser Leu Glu Asn Ala Asn Tyr Lys
1 5 10 15
<210> 765
<211> 6
<212> PRT
<213> Homo sapiens
<400> 765
Asp Met Val Glu Tyr Lys
1 5
<210> 766
<211> 8
<212> PRT
<213> Homo sapiens
<400> 766
Asp Met Val Glu Tyr Lys Asp Arg
1 5
<210> 767
<211> 12
<212> PRT
<213> Homo sapiens
<400> 767
Asp Met Tyr Ser Phe Leu Glu Asp Met Gly Leu Lys
1 5 10
<210> 768
<211> 11
<212> PRT
<213> Homo sapiens
<400> 768
Asp Asn Asp Gly Trp Leu Thr Ser Asp Pro Arg
1 5 10
<210> 769
<211> 12
<212> PRT
<213> Homo sapiens
<400> 769
Asp Asn Asp Gly Trp Leu Thr Ser Asp Pro Arg Lys
1 5 10
<210> 770
<211> 10
<212> PRT
<213> Homo sapiens
<400> 770
Asp Asn Glu Asp Phe Gln Glu Ser Asn Arg
1 5 10
<210> 771
<211> 12
<212> PRT
<213> Homo sapiens
<400> 771
Asp Asn Glu Glu Thr Gly Phe Gly Ser Gly Thr Arg
1 5 10
<210> 772
<211> 8
<212> PRT
<213> Homo sapiens
<400> 772
Asp Asn Glu Leu Leu Val Tyr Lys
1 5
<210> 773
<211> 10
<212> PRT
<213> Homo sapiens
<400> 773
Asp Asn Glu Leu Leu Val Tyr Lys Glu Arg
1 5 10
<210> 774
<211> 15
<212> PRT
<213> Homo sapiens
<400> 774
Asp Asn Glu Asn Val Val Asn Glu Tyr Ser Ser Glu Leu Glu Lys
1 5 10 15
<210> 775
<211> 33
<212> PRT
<213> Homo sapiens
<400> 775
Asp Asn Glu Asn Val Val Asn Glu Tyr Ser Ser Glu Leu Glu Lys His
1 5 10 15
Gln Leu Tyr Ile Asp Glu Thr Val Asn Ser Asn Ile Pro Thr Asn Leu
20 25 30
Arg
<210> 776
<211> 8
<212> PRT
<213> Homo sapiens
<400> 776
Asp Asn Glu Gln His Val Phe Lys
1 5
<210> 777
<211> 6
<212> PRT
<213> Homo sapiens
<400> 777
Asp Asn Gly Cys Phe Arg
1 5
<210> 778
<211> 12
<212> PRT
<213> Homo sapiens
<400> 778
Asp Asn Ile Gln Gly Ile Thr Lys Pro Ala Ile Arg
1 5 10
<210> 779
<211> 13
<212> PRT
<213> Homo sapiens
<400> 779
Asp Asn Ser Ala Leu Asp Pro Ile Ile His Gly Leu Lys
1 5 10
<210> 780
<211> 15
<212> PRT
<213> Homo sapiens
<400> 780
Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg
1 5 10 15
<210> 781
<211> 13
<212> PRT
<213> Homo sapiens
<400> 781
Asp Asn Ser Val His Trp Glu Arg Pro Gln Lys Pro Lys
1 5 10
<210> 782
<211> 11
<212> PRT
<213> Homo sapiens
<400> 782
Asp Asn Thr Ile Asn Leu Ile His Thr Phe Arg
1 5 10
<210> 783
<211> 6
<212> PRT
<213> Homo sapiens
<400> 783
Asp Asn Thr Tyr Asn Arg
1 5
<210> 784
<211> 14
<212> PRT
<213> Homo sapiens
<400> 784
Asp Asn Val Glu Met Asp Thr Phe Gln Ile Glu Cys Leu Lys
1 5 10
<210> 785
<211> 9
<212> PRT
<213> Homo sapiens
<400> 785
Asp Asn Val Phe Asp Gly Leu Val Arg
1 5
<210> 786
<211> 20
<212> PRT
<213> Homo sapiens
<400> 786
Asp Pro Ala Gly His Phe His Gln Val Trp Tyr Asp Asn Pro Gln Ser
1 5 10 15
Ile Ser Leu Lys
20
<210> 787
<211> 13
<212> PRT
<213> Homo sapiens
<400> 787
Asp Pro Asp Ala Ser Lys Pro Glu Asp Trp Asp Glu Arg
1 5 10
<210> 788
<211> 22
<212> PRT
<213> Homo sapiens
<400> 788
Asp Pro Asp Gln Thr Asp Gly Leu Gly Leu Ser Tyr Leu Ser Ser His
1 5 10 15
Ile Ala Asn Val Glu Arg
20
<210> 789
<211> 19
<212> PRT
<213> Homo sapiens
<400> 789
Asp Pro Glu Ile His Leu Ser Gly Pro Leu Glu Ala Gly Lys Pro Ile
1 5 10 15
Thr Val Lys
<210> 790
<211> 11
<212> PRT
<213> Homo sapiens
<400> 790
Asp Pro Asn Gly Leu Pro Pro Glu Ala Gln Lys
1 5 10
<210> 791
<211> 14
<212> PRT
<213> Homo sapiens
<400> 791
Asp Pro Asn His Phe Arg Pro Ala Gly Leu Pro Glu Lys Tyr
1 5 10
<210> 792
<211> 13
<212> PRT
<213> Homo sapiens
<400> 792
Asp Pro Pro Ser Trp Ser Val Leu Ala Gly His Ser Arg
1 5 10
<210> 793
<211> 6
<212> PRT
<213> Homo sapiens
<400> 793
Asp Pro Gln Phe Gln Lys
1 5
<210> 794
<211> 12
<212> PRT
<213> Homo sapiens
<400> 794
Asp Pro Thr Phe Ile Pro Ala Pro Ile Gln Ala Lys
1 5 10
<210> 795
<211> 11
<212> PRT
<213> Homo sapiens
<400> 795
Asp Pro Tyr Asp Gln Ser Pro Met Thr Pro Arg
1 5 10
<210> 796
<211> 10
<212> PRT
<213> Homo sapiens
<400> 796
Asp Gln Ala Leu Thr Glu Glu His Ala Arg
1 5 10
<210> 797
<211> 18
<212> PRT
<213> Homo sapiens
<400> 797
Asp Gln Glu Val Leu Leu Gln Thr Phe Leu Asp Asp Ala Ser Pro Gly
1 5 10 15
Asp Lys
<210> 798
<211> 19
<212> PRT
<213> Homo sapiens
<400> 798
Asp Gln Glu Val Leu Leu Gln Thr Phe Leu Asp Asp Ala Ser Pro Gly
1 5 10 15
Asp Lys Arg
<210> 799
<211> 29
<212> PRT
<213> Homo sapiens
<400> 799
Asp Gln Phe Asn Leu Ile Val Phe Ser Thr Glu Ala Thr Gln Trp Arg
1 5 10 15
Pro Ser Leu Val Pro Ala Ser Ala Glu Asn Val Asn Lys
20 25
<210> 800
<211> 9
<212> PRT
<213> Homo sapiens
<400> 800
Asp Gln Leu Ile Tyr Asn Leu Leu Lys
1 5
<210> 801
<211> 17
<212> PRT
<213> Homo sapiens
<400> 801
Asp Gln Leu Ile Tyr Asn Leu Leu Lys Glu Glu Gln Thr Pro Gln Asn
1 5 10 15
Lys
<210> 802
<211> 11
<212> PRT
<213> Homo sapiens
<400> 802
Asp Gln Leu Thr Cys Asn Lys Phe Asp Leu Lys
1 5 10
<210> 803
<211> 25
<212> PRT
<213> Homo sapiens
<400> 803
Asp Gln Asn Gln Gln Cys Ser Tyr Ile Pro Gly Ser Val Asp Asn Tyr
1 5 10 15
Gln Thr Ala Arg Ala Asp Val Glu Lys
20 25
<210> 804
<211> 11
<212> PRT
<213> Homo sapiens
<400> 804
Asp Gln Pro Arg Pro Ala Phe Ser Ala Ile Arg
1 5 10
<210> 805
<211> 20
<212> PRT
<213> Homo sapiens
<400> 805
Asp Gln Thr Ile Arg Phe Asp His Val Ile Thr Asn Met Asn Asn Asn
1 5 10 15
Tyr Glu Pro Arg
20
<210> 806
<211> 8
<212> PRT
<213> Homo sapiens
<400> 806
Asp Gln Val Glu Thr Ala Leu Lys
1 5
<210> 807
<211> 42
<212> PRT
<213> Homo sapiens
<400> 807
Asp Gln Val Asn Thr Phe Asp Asn Ile Phe Ile Ala Pro Val Gly Ile
1 5 10 15
Ser Thr Ala Met Gly Met Ile Ser Leu Gly Leu Lys Gly Glu Thr His
20 25 30
Glu Gln Val His Ser Ile Leu His Phe Lys
35 40
<210> 808
<211> 11
<212> PRT
<213> Homo sapiens
<400> 808
Asp Arg Asp Gly Asn Thr Leu Thr Tyr Tyr Arg
1 5 10
<210> 809
<211> 17
<212> PRT
<213> Homo sapiens
<400> 809
Asp Arg Asp Val Thr Phe Ser Pro Ala Thr Ile Glu Asn Glu Leu Ile
1 5 10 15
Lys
<210> 810
<211> 9
<212> PRT
<213> Homo sapiens
<400> 810
Asp Arg Gln His Leu Pro Leu Ile Lys
1 5
<210> 811
<211> 30
<212> PRT
<213> Homo sapiens
<400> 811
Asp Arg Ser Pro Cys Tyr Gly Tyr Gln Trp Val Ser Glu Glu His Glu
1 5 10 15
Glu Ala His His Thr Ala Tyr Leu Val Phe Ser Pro Ser Lys
20 25 30
<210> 812
<211> 11
<212> PRT
<213> Homo sapiens
<400> 812
Asp Arg Val Val Glu Glu Ser Glu Leu Ala Arg
1 5 10
<210> 813
<211> 8
<212> PRT
<213> Homo sapiens
<400> 813
Asp Ser Ala His Gly Phe Leu Lys
1 5
<210> 814
<211> 11
<212> PRT
<213> Homo sapiens
<400> 814
Asp Ser Cys Thr Leu Pro Ala Ser Ala Glu Lys
1 5 10
<210> 815
<211> 10
<212> PRT
<213> Homo sapiens
<400> 815
Asp Ser Cys Val Gly Ser Leu Val Val Lys
1 5 10
<210> 816
<211> 11
<212> PRT
<213> Homo sapiens
<400> 816
Asp Ser Asp Leu Leu Ser Pro Ser Asp Phe Lys
1 5 10
<210> 817
<211> 15
<212> PRT
<213> Homo sapiens
<400> 817
Asp Ser Asp Trp Pro Phe Cys Ser Asp Glu Asp Trp Asn Tyr Lys
1 5 10 15
<210> 818
<211> 8
<212> PRT
<213> Homo sapiens
<400> 818
Asp Ser Glu Ile Thr Phe Ile Lys
1 5
<210> 819
<211> 9
<212> PRT
<213> Homo sapiens
<400> 819
Asp Ser Glu Ile Thr Phe Ile Lys Lys
1 5
<210> 820
<211> 7
<212> PRT
<213> Homo sapiens
<400> 820
Asp Ser Phe Asp Ile Ile Lys
1 5
<210> 821
<211> 8
<212> PRT
<213> Homo sapiens
<400> 821
Asp Ser Phe Asp Ile Ile Lys Arg
1 5
<210> 822
<211> 19
<212> PRT
<213> Homo sapiens
<400> 822
Asp Ser Phe His Leu Asp Glu Gln Phe Thr Val Pro Val Glu Met Met
1 5 10 15
Gln Ala Arg
<210> 823
<211> 7
<212> PRT
<213> Homo sapiens
<400> 823
Asp Ser Phe Ser Asn Glu Lys
1 5
<210> 824
<211> 10
<212> PRT
<213> Homo sapiens
<400> 824
Asp Ser Gly Phe Gln Met Asn Gln Leu Arg
1 5 10
<210> 825
<211> 17
<212> PRT
<213> Homo sapiens
<400> 825
Asp Ser Gly Arg Asp Tyr Val Ser Gln Phe Glu Gly Ser Ala Leu Gly
1 5 10 15
Lys
<210> 826
<211> 14
<212> PRT
<213> Homo sapiens
<400> 826
Asp Ser His Ser Leu Thr Thr Asn Ile Met Glu Ile Leu Arg
1 5 10
<210> 827
<211> 5
<212> PRT
<213> Homo sapiens
<400> 827
Asp Ser Ile Leu Lys
1 5
<210> 828
<211> 5
<212> PRT
<213> Homo sapiens
<400> 828
Asp Ser Ile Ser Arg
1 5
<210> 829
<211> 17
<212> PRT
<213> Homo sapiens
<400> 829
Asp Ser Ile Thr Thr Trp Glu Ile Leu Ala Val Ser Met Ser Asp Lys
1 5 10 15
Lys
<210> 830
<211> 7
<212> PRT
<213> Homo sapiens
<400> 830
Asp Ser Leu Asp Lys Glu Lys
1 5
<210> 831
<211> 6
<212> PRT
<213> Homo sapiens
<400> 831
Asp Ser Leu Glu Phe Arg
1 5
<210> 832
<211> 15
<212> PRT
<213> Homo sapiens
<400> 832
Asp Ser Leu Glu Phe Arg Glu Ile Gly Glu Leu Tyr Leu Pro Lys
1 5 10 15
<210> 833
<211> 5
<212> PRT
<213> Homo sapiens
<400> 833
Asp Ser Leu Ile Lys
1 5
<210> 834
<211> 5
<212> PRT
<213> Homo sapiens
<400> 834
Asp Ser Leu Leu Lys
1 5
<210> 835
<211> 11
<212> PRT
<213> Homo sapiens
<400> 835
Asp Ser Leu Ser Ile Asn Ala Thr Asn Ile Lys
1 5 10
<210> 836
<211> 5
<212> PRT
<213> Homo sapiens
<400> 836
Asp Ser Leu Ser Arg
1 5
<210> 837
<211> 8
<212> PRT
<213> Homo sapiens
<400> 837
Asp Ser Leu Val Leu Leu Gly Arg
1 5
<210> 838
<211> 12
<212> PRT
<213> Homo sapiens
<400> 838
Asp Ser Pro Ser Val Trp Ala Ala Val Pro Gly Lys
1 5 10
<210> 839
<211> 14
<212> PRT
<213> Homo sapiens
<400> 839
Asp Ser Pro Val Leu Ile Asp Phe Phe Glu Asp Thr Glu Arg
1 5 10
<210> 840
<211> 15
<212> PRT
<213> Homo sapiens
<400> 840
Asp Ser Gln Glu Glu Glu Lys Thr Glu Ala Leu Thr Ser Ala Lys
1 5 10 15
<210> 841
<211> 6
<212> PRT
<213> Homo sapiens
<400> 841
Asp Ser Ser Phe Ile Arg
1 5
<210> 842
<211> 12
<212> PRT
<213> Homo sapiens
<400> 842
Asp Ser Ser Thr Trp Leu Thr Ala Phe Val Leu Lys
1 5 10
<210> 843
<211> 11
<212> PRT
<213> Homo sapiens
<400> 843
Asp Ser Ser Val Pro Asn Thr Gly Thr Ala Arg
1 5 10
<210> 844
<211> 7
<212> PRT
<213> Homo sapiens
<400> 844
Asp Ser Val Ser Leu Arg Lys
1 5
<210> 845
<211> 9
<212> PRT
<213> Homo sapiens
<400> 845
Asp Ser Val Thr Glu Thr Leu Pro Arg
1 5
<210> 846
<211> 9
<212> PRT
<213> Homo sapiens
<400> 846
Asp Ser Val Thr Gly Thr Leu Pro Lys
1 5
<210> 847
<211> 6
<212> PRT
<213> Homo sapiens
<400> 847
Asp Ser Val Thr Leu Lys
1 5
<210> 848
<211> 6
<212> PRT
<213> Homo sapiens
<400> 848
Asp Ser Trp Leu Asp Lys
1 5
<210> 849
<211> 9
<212> PRT
<213> Homo sapiens
<400> 849
Asp Ser Tyr Asp Leu His Asp Leu Lys
1 5
<210> 850
<211> 11
<212> PRT
<213> Homo sapiens
<400> 850
Asp Ser Tyr Val Gly Asp Glu Ala Gln Ser Lys
1 5 10
<210> 851
<211> 38
<212> PRT
<213> Homo sapiens
<400> 851
Asp Thr Ala Asn Leu Phe Pro Gln Thr Ser Leu Thr Leu His Met Trp
1 5 10 15
Pro Asp Thr Glu Gly Thr Phe Asn Val Glu Cys Leu Thr Thr Asp His
20 25 30
Tyr Thr Gly Gly Met Lys
35
<210> 852
<211> 7
<212> PRT
<213> Homo sapiens
<400> 852
Asp Thr Asp Gly Asp Gly Arg
1 5
<210> 853
<211> 32
<212> PRT
<213> Homo sapiens
<400> 853
Asp Thr Asp Arg Phe Ser Ser His Val Gly Gly Thr Leu Gly Gln Phe
1 5 10 15
Tyr Gln Glu Val Leu Trp Gly Ser Pro Ala Ala Ser Asp Asp Gly Arg
20 25 30
<210> 854
<211> 12
<212> PRT
<213> Homo sapiens
<400> 854
Asp Thr Asp Thr Gly Ala Leu Leu Phe Ile Gly Lys
1 5 10
<210> 855
<211> 16
<212> PRT
<213> Homo sapiens
<400> 855
Asp Thr Glu Glu Glu Asp Phe His Val Asp Gln Val Thr Thr Val Lys
1 5 10 15
<210> 856
<211> 21
<212> PRT
<213> Homo sapiens
<400> 856
Asp Thr Glu Glu Glu Asp Phe His Val Asp Gln Val Thr Thr Val Lys
1 5 10 15
Val Pro Met Met Lys
20
<210> 857
<211> 15
<212> PRT
<213> Homo sapiens
<400> 857
Asp Thr Gly Glu Asn Leu Glu Thr Pro Ser Ser Phe Thr Ile Lys
1 5 10 15
<210> 858
<211> 6
<212> PRT
<213> Homo sapiens
<400> 858
Asp Thr Ile Val Phe Lys
1 5
<210> 859
<211> 22
<212> PRT
<213> Homo sapiens
<400> 859
Asp Thr Leu Thr Ser Arg Pro Ala Gln Gly Val Val Thr Thr Leu Glu
1 5 10 15
Asn Val Ser Pro Pro Arg
20
<210> 860
<211> 23
<212> PRT
<213> Homo sapiens
<400> 860
Asp Thr Leu Thr Ser Arg Pro Ala Gln Gly Val Val Thr Thr Leu Glu
1 5 10 15
Asn Val Ser Pro Pro Arg Arg
20
<210> 861
<211> 12
<212> PRT
<213> Homo sapiens
<400> 861
Asp Thr Met Val Glu Asp Leu Val Val Leu Val Arg
1 5 10
<210> 862
<211> 8
<212> PRT
<213> Homo sapiens
<400> 862
Asp Thr Pro Phe Ser Gln Ile Lys
1 5
<210> 863
<211> 17
<212> PRT
<213> Homo sapiens
<400> 863
Asp Thr Pro Phe Ser Gln Ile Lys Glu Ile Ile Ile His Gln Asn Tyr
1 5 10 15
Lys
<210> 864
<211> 13
<212> PRT
<213> Homo sapiens
<400> 864
Asp Thr Val Phe Ala Leu Val Asn Tyr Ile Phe Phe Lys
1 5 10
<210> 865
<211> 16
<212> PRT
<213> Homo sapiens
<400> 865
Asp Thr Val Ile Lys Pro Leu Leu Val Glu Pro Glu Gly Leu Glu Lys
1 5 10 15
<210> 866
<211> 11
<212> PRT
<213> Homo sapiens
<400> 866
Asp Thr Val Gln Ile His Asp Ile Thr Gly Lys
1 5 10
<210> 867
<211> 19
<212> PRT
<213> Homo sapiens
<400> 867
Asp Thr Val Gln Ile His Asp Ile Thr Gly Lys Asp Cys Gln Asp Ile
1 5 10 15
Ala Asn Lys
<210> 868
<211> 10
<212> PRT
<213> Homo sapiens
<400> 868
Asp Val Ala Ala Glu Ala Gly Val Ser Lys
1 5 10
<210> 869
<211> 11
<212> PRT
<213> Homo sapiens
<400> 869
Asp Val Ala Val Ser Tyr Tyr His Phe His Arg
1 5 10
<210> 870
<211> 9
<212> PRT
<213> Homo sapiens
<400> 870
Asp Val Cys Asp Pro Gly Asn Thr Lys
1 5
<210> 871
<211> 9
<212> PRT
<213> Homo sapiens
<400> 871
Asp Val Asp Gly Ala Tyr Met Thr Lys
1 5
<210> 872
<211> 15
<212> PRT
<213> Homo sapiens
<400> 872
Asp Val Asp Ile Ile Asp His His Asp Asn Thr Tyr Thr Val Lys
1 5 10 15
<210> 873
<211> 7
<212> PRT
<213> Homo sapiens
<400> 873
Asp Val Asp Asn Ala Leu Arg
1 5
<210> 874
<211> 9
<212> PRT
<213> Homo sapiens
<400> 874
Asp Val Asp Asn Ala Tyr Met Ile Lys
1 5
<210> 875
<211> 13
<212> PRT
<213> Homo sapiens
<400> 875
Asp Val Phe Leu Gly Met Phe Leu Tyr Glu Tyr Ala Arg
1 5 10
<210> 876
<211> 12
<212> PRT
<213> Homo sapiens
<400> 876
Asp Val His Glu Gly Gln Pro Leu Leu Asn Val Lys
1 5 10
<210> 877
<211> 5
<212> PRT
<213> Homo sapiens
<400> 877
Asp Val Ile Val Arg
1 5
<210> 878
<211> 11
<212> PRT
<213> Homo sapiens
<400> 878
Asp Val Leu Leu Gln Val Asp Asp Glu Arg Arg
1 5 10
<210> 879
<211> 13
<212> PRT
<213> Homo sapiens
<400> 879
Asp Val Leu Met Val Leu Val Asn Tyr Ile Tyr Phe Lys
1 5 10
<210> 880
<211> 5
<212> PRT
<213> Homo sapiens
<400> 880
Asp Val Leu Val Arg
1 5
<210> 881
<211> 7
<212> PRT
<213> Homo sapiens
<400> 881
Asp Val Val Leu Phe Glu Lys
1 5
<210> 882
<211> 13
<212> PRT
<213> Homo sapiens
<400> 882
Asp Val Val Leu Thr Thr Thr Phe Val Asp Asp Ile Lys
1 5 10
<210> 883
<211> 15
<212> PRT
<213> Homo sapiens
<400> 883
Asp Val Trp Gly Ile Glu Gly Pro Ile Asp Ala Ala Phe Thr Arg
1 5 10 15
<210> 884
<211> 23
<212> PRT
<213> Homo sapiens
<400> 884
Asp Val Tyr Leu Leu His Glu Ser Tyr Asp Asp Val Gln Gln Ser Phe
1 5 10 15
Phe Leu Ala Glu Thr Leu Lys
20
<210> 885
<211> 16
<212> PRT
<213> Homo sapiens
<400> 885
Asp Trp His Gly Val Pro Gly Gln Val Asp Ala Ala Met Ala Gly Arg
1 5 10 15
<210> 886
<211> 7
<212> PRT
<213> Homo sapiens
<400> 886
Asp Tyr Glu Asp Gln Gln Lys
1 5
<210> 887
<211> 12
<212> PRT
<213> Homo sapiens
<400> 887
Asp Tyr Glu Asn Gly Phe Gly Asn Phe Val Gln Lys
1 5 10
<210> 888
<211> 11
<212> PRT
<213> Homo sapiens
<400> 888
Asp Tyr Glu Thr Ala Thr Leu Ser Glu Ile Lys
1 5 10
<210> 889
<211> 8
<212> PRT
<213> Homo sapiens
<400> 889
Asp Tyr Phe Ile Ala Thr Cys Lys
1 5
<210> 890
<211> 9
<212> PRT
<213> Homo sapiens
<400> 890
Asp Tyr Phe Met Pro Cys Pro Gly Arg
1 5
<210> 891
<211> 7
<212> PRT
<213> Homo sapiens
<400> 891
Asp Tyr Ile Glu Phe Asn Lys
1 5
<210> 892
<211> 10
<212> PRT
<213> Homo sapiens
<400> 892
Asp Tyr Ile Phe Gly Asn Tyr Ile Glu Arg
1 5 10
<210> 893
<211> 21
<212> PRT
<213> Homo sapiens
<400> 893
Asp Tyr Leu Ile Glu Asp Gly Thr Val His Leu Val Tyr Gly Ile Leu
1 5 10 15
Glu Glu Pro Phe Arg
20
<210> 894
<211> 5
<212> PRT
<213> Homo sapiens
<400> 894
Asp Tyr Leu Val Lys
1 5
<210> 895
<211> 20
<212> PRT
<213> Homo sapiens
<400> 895
Asp Tyr Asn Leu Asn Asp Ile Leu Leu Gln Leu Gly Ile Glu Glu Ala
1 5 10 15
Phe Thr Ser Lys
20
<210> 896
<211> 30
<212> PRT
<213> Homo sapiens
<400> 896
Asp Tyr Asn Leu Asn Asp Ile Leu Leu Gln Leu Gly Ile Glu Glu Ala
1 5 10 15
Phe Thr Ser Lys Ala Asp Leu Ser Gly Ile Thr Gly Ala Arg
20 25 30
<210> 897
<211> 9
<212> PRT
<213> Homo sapiens
<400> 897
Asp Tyr Asn Val Thr Ala Asn Ser Lys
1 5
<210> 898
<211> 9
<212> PRT
<213> Homo sapiens
<400> 898
Asp Tyr Gln Glu Leu Met Asn Thr Lys
1 5
<210> 899
<211> 22
<212> PRT
<213> Homo sapiens
<400> 899
Asp Tyr Gln Glu Met Ile Glu Asn Tyr Val His Trp Asn Glu Asp Ile
1 5 10 15
Gly Glu Trp Gln Leu Lys
20
<210> 900
<211> 9
<212> PRT
<213> Homo sapiens
<400> 900
Asp Tyr Ser Gly Gln Gly Val Val Lys
1 5
<210> 901
<211> 9
<212> PRT
<213> Homo sapiens
<400> 901
Asp Tyr Ser Val Thr Ala Asn Ser Lys
1 5
<210> 902
<211> 5
<212> PRT
<213> Homo sapiens
<400> 902
Asp Tyr Val Glu Lys
1 5
<210> 903
<211> 13
<212> PRT
<213> Homo sapiens
<400> 903
Asp Tyr Val Ser Gln Phe Glu Gly Ser Ala Leu Gly Lys
1 5 10
<210> 904
<211> 7
<212> PRT
<213> Homo sapiens
<400> 904
Asp Tyr Trp Ser Thr Val Lys
1 5
<210> 905
<211> 9
<212> PRT
<213> Homo sapiens
<400> 905
Asp Tyr Trp Ser Thr Val Lys Asp Lys
1 5
<210> 906
<211> 13
<212> PRT
<213> Homo sapiens
<400> 906
Glu Ala Ala Tyr His Pro Glu Val Ala Pro Asp Val Arg
1 5 10
<210> 907
<211> 17
<212> PRT
<213> Homo sapiens
<400> 907
Glu Ala Asp Glu Ser Leu Asn Phe Glu Glu Gln Ile Leu Glu Ala Ala
1 5 10 15
Lys
<210> 908
<211> 16
<212> PRT
<213> Homo sapiens
<400> 908
Glu Ala Glu Ala Ala Ile Tyr His Leu Gln Leu Phe Glu Glu Leu Arg
1 5 10 15
<210> 909
<211> 17
<212> PRT
<213> Homo sapiens
<400> 909
Glu Ala Glu Ala Ala Ile Tyr His Leu Gln Leu Phe Glu Glu Leu Arg
1 5 10 15
Arg
<210> 910
<211> 9
<212> PRT
<213> Homo sapiens
<400> 910
Glu Ala Glu Gly Pro Leu Pro Ile Lys
1 5
<210> 911
<211> 6
<212> PRT
<213> Homo sapiens
<400> 911
Glu Ala Glu Ile Ile Lys
1 5
<210> 912
<211> 17
<212> PRT
<213> Homo sapiens
<400> 912
Glu Ala Glu Asn Phe His Glu Glu Asp Asp Val Asp Val Arg Pro Ala
1 5 10 15
Arg
<210> 913
<211> 9
<212> PRT
<213> Homo sapiens
<400> 913
Glu Ala Glu Pro Leu Val Asp Ile Arg
1 5
<210> 914
<211> 7
<212> PRT
<213> Homo sapiens
<400> 914
Glu Ala Glu Val Leu Leu Lys
1 5
<210> 915
<211> 8
<212> PRT
<213> Homo sapiens
<400> 915
Glu Ala Phe Ala Ala Val Ser Lys
1 5
<210> 916
<211> 15
<212> PRT
<213> Homo sapiens
<400> 916
Glu Ala Phe Ala Ala Val Ser Lys Ile Ala Trp His Val Ile Arg
1 5 10 15
<210> 917
<211> 7
<212> PRT
<213> Homo sapiens
<400> 917
Glu Ala Phe Glu Ile Ser Lys
1 5
<210> 918
<211> 8
<212> PRT
<213> Homo sapiens
<400> 918
Glu Ala Phe Glu Leu Phe Asp Arg
1 5
<210> 919
<211> 8
<212> PRT
<213> Homo sapiens
<400> 919
Glu Ala Phe Gln Leu Phe Asp Arg
1 5
<210> 920
<211> 8
<212> PRT
<213> Homo sapiens
<400> 920
Glu Ala Phe Ser Leu Phe Asp Lys
1 5
<210> 921
<211> 16
<212> PRT
<213> Homo sapiens
<400> 921
Glu Ala Gly Ala Gly Gly Leu Ala Ile Ala Val Glu Gly Pro Ser Lys
1 5 10 15
<210> 922
<211> 16
<212> PRT
<213> Homo sapiens
<400> 922
Glu Ala Gly Ile Pro Glu Phe Tyr Asp Tyr Asp Val Ala Leu Ile Lys
1 5 10 15
<210> 923
<211> 7
<212> PRT
<213> Homo sapiens
<400> 923
Glu Ala Gly Leu Asp Leu Arg
1 5
<210> 924
<211> 18
<212> PRT
<213> Homo sapiens
<400> 924
Glu Ala Gly Gln Phe Gly His Asp Ile His His Thr Ala Gly Gln Ala
1 5 10 15
Gly Lys
<210> 925
<211> 19
<212> PRT
<213> Homo sapiens
<400> 925
Glu Ala Gly Ser Gln Lys Asp Glu Asn Leu Ala Leu Tyr Val Glu Asn
1 5 10 15
Gln Phe Arg
<210> 926
<211> 5
<212> PRT
<213> Homo sapiens
<400> 926
Glu Ala Ile Ile Lys
1 5
<210> 927
<211> 5
<212> PRT
<213> Homo sapiens
<400> 927
Glu Ala Ile Ile Arg
1 5
<210> 928
<211> 5
<212> PRT
<213> Homo sapiens
<400> 928
Glu Ala Ile Leu Lys
1 5
<210> 929
<211> 5
<212> PRT
<213> Homo sapiens
<400> 929
Glu Ala Ile Leu Arg
1 5
<210> 930
<211> 5
<212> PRT
<213> Homo sapiens
<400> 930
Glu Ala Ile Val Lys
1 5
<210> 931
<211> 10
<212> PRT
<213> Homo sapiens
<400> 931
Glu Ala Leu Ala Ile Val Phe Phe Gly Arg
1 5 10
<210> 932
<211> 5
<212> PRT
<213> Homo sapiens
<400> 932
Glu Ala Leu Ile Lys
1 5
<210> 933
<211> 15
<212> PRT
<213> Homo sapiens
<400> 933
Glu Ala Leu Ile Gln Phe Leu Glu Gln Val His Gln Gly Ile Lys
1 5 10 15
<210> 934
<211> 5
<212> PRT
<213> Homo sapiens
<400> 934
Glu Ala Leu Ile Arg
1 5
<210> 935
<211> 15
<212> PRT
<213> Homo sapiens
<400> 935
Glu Ala Leu Lys Glu Ser Gln Leu Pro Thr Val Met Asp Phe Arg
1 5 10 15
<210> 936
<211> 8
<212> PRT
<213> Homo sapiens
<400> 936
Glu Ala Leu Lys Leu Glu Glu Lys
1 5
<210> 937
<211> 5
<212> PRT
<213> Homo sapiens
<400> 937
Glu Ala Leu Leu Lys
1 5
<210> 938
<211> 5
<212> PRT
<213> Homo sapiens
<400> 938
Glu Ala Leu Leu Arg
1 5
<210> 939
<211> 11
<212> PRT
<213> Homo sapiens
<400> 939
Glu Ala Leu Gln Gly Val Gly Asp Met Gly Arg
1 5 10
<210> 940
<211> 6
<212> PRT
<213> Homo sapiens
<400> 940
Glu Ala Leu Gln Ile Lys
1 5
<210> 941
<211> 12
<212> PRT
<213> Homo sapiens
<400> 941
Glu Ala Leu Gln Ile Lys Tyr Asn Phe Ser Phe Arg
1 5 10
<210> 942
<211> 5
<212> PRT
<213> Homo sapiens
<400> 942
Glu Ala Leu Val Lys
1 5
<210> 943
<211> 11
<212> PRT
<213> Homo sapiens
<400> 943
Glu Ala Leu Val Pro Leu Val Ala Asp His Lys
1 5 10
<210> 944
<211> 9
<212> PRT
<213> Homo sapiens
<400> 944
Glu Ala Asn Tyr Ile Gly Ser Asp Lys
1 5
<210> 945
<211> 9
<212> PRT
<213> Homo sapiens
<400> 945
Glu Ala Pro Asp Leu Val Leu Gln Arg
1 5
<210> 946
<211> 12
<212> PRT
<213> Homo sapiens
<400> 946
Glu Ala Pro Lys Val Val Glu Glu Gln Glu Ser Arg
1 5 10
<210> 947
<211> 6
<212> PRT
<213> Homo sapiens
<400> 947
Glu Ala Pro Leu Gln Lys
1 5
<210> 948
<211> 7
<212> PRT
<213> Homo sapiens
<400> 948
Glu Ala Gln Glu Val Phe Lys
1 5
<210> 949
<211> 10
<212> PRT
<213> Homo sapiens
<400> 949
Glu Ala Gln Leu Pro Val Ile Glu Asn Lys
1 5 10
<210> 950
<211> 22
<212> PRT
<213> Homo sapiens
<400> 950
Glu Ala Ser Met Glu Gly Ile Val Thr Ile Val Gly Leu Lys Pro Glu
1 5 10 15
Thr Thr Tyr Ala Val Arg
20
<210> 951
<211> 11
<212> PRT
<213> Homo sapiens
<400> 951
Glu Ala Thr Asp Val Ile Ile Ile His Ser Lys
1 5 10
<210> 952
<211> 14
<212> PRT
<213> Homo sapiens
<400> 952
Glu Ala Thr Glu Ala Ala Lys Cys Asn Leu Leu Ala Glu Lys
1 5 10
<210> 953
<211> 14
<212> PRT
<213> Homo sapiens
<400> 953
Glu Ala Thr Ile Pro Gly His Leu Asn Ser Tyr Thr Ile Lys
1 5 10
<210> 954
<211> 14
<212> PRT
<213> Homo sapiens
<400> 954
Glu Ala Thr Asn Pro Pro Val Ile Gln Glu Glu Lys Pro Lys
1 5 10
<210> 955
<211> 8
<212> PRT
<213> Homo sapiens
<400> 955
Glu Ala Val Glu His Leu Gln Lys
1 5
<210> 956
<211> 18
<212> PRT
<213> Homo sapiens
<400> 956
Glu Ala Val Lys Glu Asp Asn Leu Val His Trp Glu Arg Pro Gln Arg
1 5 10 15
Pro Lys
<210> 957
<211> 27
<212> PRT
<213> Homo sapiens
<400> 957
Glu Ala Val Leu Ile Gln Ala Gly Glu Tyr Met Gly Gln Leu Leu Glu
1 5 10 15
Gln Ala Ser Leu His Phe Phe Val Thr Ala Arg
20 25
<210> 958
<211> 23
<212> PRT
<213> Homo sapiens
<400> 958
Glu Ala Val Met Asp Ile Asn Lys Pro Gly Pro Leu Phe Lys Pro Glu
1 5 10 15
Asn Gly Leu Leu Glu Thr Lys
20
<210> 959
<211> 7
<212> PRT
<213> Homo sapiens
<400> 959
Glu Ala Tyr Gln Ser Met Lys
1 5
<210> 960
<211> 7
<212> PRT
<213> Homo sapiens
<400> 960
Glu Cys Glu Glu Ile Ile Arg
1 5
<210> 961
<211> 8
<212> PRT
<213> Homo sapiens
<400> 961
Glu Cys Glu Glu Ile Ile Arg Lys
1 5
<210> 962
<211> 6
<212> PRT
<213> Homo sapiens
<400> 962
Glu Cys Glu Leu Pro Lys
1 5
<210> 963
<211> 9
<212> PRT
<213> Homo sapiens
<400> 963
Glu Cys Asn Asn Pro Ala Pro Gln Arg
1 5
<210> 964
<211> 12
<212> PRT
<213> Homo sapiens
<400> 964
Glu Cys Asn Asn Pro Pro Pro Ser Gly Gly Gly Arg
1 5 10
<210> 965
<211> 9
<212> PRT
<213> Homo sapiens
<400> 965
Glu Asp Ala Ala Asn Asn Tyr Ala Arg
1 5
<210> 966
<211> 9
<212> PRT
<213> Homo sapiens
<400> 966
Glu Asp Ala Val Ser Ala Ala Phe Lys
1 5
<210> 967
<211> 10
<212> PRT
<213> Homo sapiens
<400> 967
Glu Asp Glu Asp Phe Gln Glu Ser Asn Lys
1 5 10
<210> 968
<211> 5
<212> PRT
<213> Homo sapiens
<400> 968
Glu Asp Phe Asp Lys
1 5
<210> 969
<211> 13
<212> PRT
<213> Homo sapiens
<400> 969
Glu Asp Phe Thr Ser Leu Ser Leu Val Leu Tyr Ser Arg
1 5 10
<210> 970
<211> 10
<212> PRT
<213> Homo sapiens
<400> 970
Glu Asp Gly Gly Gly Trp Trp Tyr Asn Arg
1 5 10
<210> 971
<211> 9
<212> PRT
<213> Homo sapiens
<400> 971
Glu Asp Ile Phe Met Glu Thr Leu Lys
1 5
<210> 972
<211> 9
<212> PRT
<213> Homo sapiens
<400> 972
Glu Asp Lys Tyr Glu Glu Glu Ile Lys
1 5
<210> 973
<211> 5
<212> PRT
<213> Homo sapiens
<400> 973
Glu Asp Leu Cys Arg
1 5
<210> 974
<211> 17
<212> PRT
<213> Homo sapiens
<400> 974
Glu Asp Leu Ile Trp Glu Leu Leu Asn Gln Ala Gln Glu His Phe Gly
1 5 10 15
Lys
<210> 975
<211> 19
<212> PRT
<213> Homo sapiens
<400> 975
Glu Asp Leu Ile Trp Glu Leu Leu Asn Gln Ala Gln Glu His Phe Gly
1 5 10 15
Lys Asp Lys
<210> 976
<211> 8
<212> PRT
<213> Homo sapiens
<400> 976
Glu Asp Leu Lys Asp Asp Gln Lys
1 5
<210> 977
<211> 5
<212> PRT
<213> Homo sapiens
<400> 977
Glu Asp Leu Pro Lys
1 5
<210> 978
<211> 12
<212> PRT
<213> Homo sapiens
<400> 978
Glu Asp Leu Arg Leu Pro Glu Gly Asp Leu Gly Lys
1 5 10
<210> 979
<211> 14
<212> PRT
<213> Homo sapiens
<400> 979
Glu Asp Asn Leu Val His Trp Glu Arg Pro Gln Arg Pro Lys
1 5 10
<210> 980
<211> 24
<212> PRT
<213> Homo sapiens
<400> 980
Glu Asp Pro Ala Tyr Leu His Tyr Tyr Asp Pro Ala Gly Ala Glu Asp
1 5 10 15
Pro Leu Gly Ala Ile His Leu Arg
20
<210> 981
<211> 14
<212> PRT
<213> Homo sapiens
<400> 981
Glu Asp Pro Gln Thr Phe Tyr Tyr Ala Val Ala Val Val Lys
1 5 10
<210> 982
<211> 15
<212> PRT
<213> Homo sapiens
<400> 982
Glu Asp Pro Gln Thr Phe Tyr Tyr Ala Val Ala Val Val Lys Lys
1 5 10 15
<210> 983
<211> 10
<212> PRT
<213> Homo sapiens
<400> 983
Glu Asp Gln Tyr His Tyr Leu Leu Asp Arg
1 5 10
<210> 984
<211> 8
<212> PRT
<213> Homo sapiens
<400> 984
Glu Asp Arg Val Pro His Ser Arg
1 5
<210> 985
<211> 9
<212> PRT
<213> Homo sapiens
<400> 985
Glu Asp Arg Tyr Glu Glu Glu Ile Lys
1 5
<210> 986
<211> 12
<212> PRT
<213> Homo sapiens
<400> 986
Glu Asp Thr Pro Asn Ser Val Trp Glu Pro Ala Lys
1 5 10
<210> 987
<211> 18
<212> PRT
<213> Homo sapiens
<400> 987
Glu Asp Thr Ser Phe Phe Gly Val Gln Glu Ile Ile Ile His Asp Gln
1 5 10 15
Tyr Lys
<210> 988
<211> 11
<212> PRT
<213> Homo sapiens
<400> 988
Glu Asp Val Tyr Val Val Gly Thr Val Leu Arg
1 5 10
<210> 989
<211> 11
<212> PRT
<213> Homo sapiens
<400> 989
Glu Glu Ala Phe Leu Gly Ile Thr Asp Glu Lys
1 5 10
<210> 990
<211> 23
<212> PRT
<213> Homo sapiens
<400> 990
Glu Glu Ala Phe Leu Gly Ile Thr Asp Glu Lys Thr Glu Gly Gln Phe
1 5 10 15
Val Asp Leu Thr Gly Asn Arg
20
<210> 991
<211> 19
<212> PRT
<213> Homo sapiens
<400> 991
Glu Glu Ala Pro Ser Leu Arg Pro Ala Pro Pro Pro Ile Ser Gly Gly
1 5 10 15
Gly Tyr Arg
<210> 992
<211> 9
<212> PRT
<213> Homo sapiens
<400> 992
Glu Glu Phe His Glu Gln Ser Phe Arg
1 5
<210> 993
<211> 11
<212> PRT
<213> Homo sapiens
<400> 993
Glu Glu Ile Gly Lys Glu Leu Glu Glu Leu Arg
1 5 10
<210> 994
<211> 9
<212> PRT
<213> Homo sapiens
<400> 994
Glu Glu Ile Ile Tyr Glu Cys Asp Lys
1 5
<210> 995
<211> 8
<212> PRT
<213> Homo sapiens
<400> 995
Glu Glu Ile Leu Ala Gln Ala Lys
1 5
<210> 996
<211> 9
<212> PRT
<213> Homo sapiens
<400> 996
Glu Glu Ile Leu Met His Leu Trp Arg
1 5
<210> 997
<211> 10
<212> PRT
<213> Homo sapiens
<400> 997
Glu Glu Leu Ile Gly Ile Ala Tyr Asn Arg
1 5 10
<210> 998
<211> 10
<212> PRT
<213> Homo sapiens
<400> 998
Glu Glu Leu Leu Pro Ala Gln Asp Ile Lys
1 5 10
<210> 999
<211> 7
<212> PRT
<213> Homo sapiens
<400> 999
Glu Glu Leu Asn Ala Leu Lys
1 5
<210> 1000
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1000
Glu Glu Leu Val Tyr Glu Leu Asn Pro Leu Asp His Arg
1 5 10
<210> 1001
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1001
Glu Glu Asn Phe Tyr Val Asp Glu Thr Thr Val Val Lys
1 5 10
<210> 1002
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1002
Glu Glu Ser Pro Leu Leu Ile Gly Gln Gln Ser Thr Val Ser Asp Val
1 5 10 15
Pro Arg
<210> 1003
<211> 28
<212> PRT
<213> Homo sapiens
<400> 1003
Glu Glu Ser Ser Ser Gly Ser Ser His Ala Val Met Asp Ile Ser Leu
1 5 10 15
Pro Thr Gly Ile Ser Ala Asn Glu Glu Asp Leu Lys
20 25
<210> 1004
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1004
Glu Glu Thr Gly Gln Val Leu Glu Arg
1 5
<210> 1005
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1005
Glu Glu Tyr Gly His Ser Glu Val Val Glu Tyr Tyr Cys Asn Pro Arg
1 5 10 15
<210> 1006
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1006
Glu Glu Tyr Ser Asn Leu Lys
1 5
<210> 1007
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1007
Glu Phe Asp His Asn Ser Asn Ile Arg
1 5
<210> 1008
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1008
Glu Phe Phe Asn Gly Lys
1 5
<210> 1009
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1009
Glu Phe Gly Asn Thr Leu Glu Asp Lys
1 5
<210> 1010
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1010
Glu Phe His Leu His Leu Arg
1 5
<210> 1011
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1011
Glu Phe His Thr Thr Gly Leu Ala Trp Ser Lys
1 5 10
<210> 1012
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1012
Glu Phe Ile Leu Gln Lys
1 5
<210> 1013
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1013
Glu Phe Leu Ile Glu Lys
1 5
<210> 1014
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1014
Glu Phe Met Glu Glu Val Ile Gln Arg
1 5
<210> 1015
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1015
Glu Phe Met Ser Gln Gly Asn Lys
1 5
<210> 1016
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1016
Glu Phe Asn Ala Glu Thr Phe Thr Phe His Ala Asp Ile Cys Thr Leu
1 5 10 15
Ser Glu Lys
<210> 1017
<211> 21
<212> PRT
<213> Homo sapiens
<400> 1017
Glu Phe Asn Ala Glu Thr Phe Thr Phe His Ala Asp Ile Cys Thr Leu
1 5 10 15
Ser Glu Lys Glu Arg
20
<210> 1018
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1018
Glu Phe Asn Lys Tyr Asp Thr Asp Gly Ser Lys
1 5 10
<210> 1019
<211> 21
<212> PRT
<213> Homo sapiens
<400> 1019
Glu Phe Asn Leu Gln Asn Met Gly Leu Pro Asp Phe His Ile Pro Glu
1 5 10 15
Asn Leu Phe Leu Lys
20
<210> 1020
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1020
Glu Phe Asn Pro Leu Val Ile Val Gly Leu Ser Lys
1 5 10
<210> 1021
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1021
Glu Phe Pro Glu Leu Val Ala Arg
1 5
<210> 1022
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1022
Glu Phe Pro Asn Gln Glu Ser Leu Leu Lys
1 5 10
<210> 1023
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1023
Glu Phe Pro Tyr Arg
1 5
<210> 1024
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1024
Glu Phe Pro Tyr Arg Ile Pro Leu Asp Leu Val Pro Lys
1 5 10
<210> 1025
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1025
Glu Phe Gln Glu Gly Leu Lys
1 5
<210> 1026
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1026
Glu Phe Gln Leu Phe Ser Ser Pro His Gly Lys
1 5 10
<210> 1027
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1027
Glu Phe Gln Val Pro Thr Phe Thr Ile Pro Lys
1 5 10
<210> 1028
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1028
Glu Phe Ser His Leu Gly Lys
1 5
<210> 1029
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1029
Glu Phe Ser His Leu Gly Lys Glu Asp Phe Thr Ser Leu Ser Leu Val
1 5 10 15
Leu Tyr Ser Arg
20
<210> 1030
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1030
Glu Phe Thr Glu Ala Phe Leu Gly Cys Pro Ala Ile His Pro Arg
1 5 10 15
<210> 1031
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1031
Glu Phe Thr Lys Leu Glu Glu Val Leu Thr Asn Lys
1 5 10
<210> 1032
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1032
Glu Phe Thr Pro Pro Val Gln Ala Ala Tyr Gln Lys
1 5 10
<210> 1033
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1033
Glu Phe Thr Arg Pro Glu Glu Ile Ile Phe Leu Arg
1 5 10
<210> 1034
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1034
Glu Phe Val Leu Leu Phe Met Thr Phe Asp Glu Lys
1 5 10
<210> 1035
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1035
Glu Phe Val Val Met Phe Ser Val Val Asp Glu Asn Phe Ser Trp Tyr
1 5 10 15
Leu Glu Asp Asn Ile Lys
20
<210> 1036
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1036
Glu Phe Tyr Leu Phe Pro Thr Val Phe Asp Glu Asn Glu Ser Leu Leu
1 5 10 15
Leu Glu Asp Asn Ile Arg
20
<210> 1037
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1037
Glu Gly Ala Ile His Arg Glu Glu Leu Val Tyr Glu Leu Asn Pro Leu
1 5 10 15
Asp His Arg
<210> 1038
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1038
Glu Gly Ala Val Leu Ala Lys
1 5
<210> 1039
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1039
Glu Gly Asp Cys Pro Val Gln Ser Gly Lys
1 5 10
<210> 1040
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1040
Glu Gly Asp Asp Asp Arg Thr Val Cys Arg
1 5 10
<210> 1041
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1041
Glu Gly Glu Thr Ile Thr Glu Val Ile His Gly Glu Pro Ile Ile Lys
1 5 10 15
<210> 1042
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1042
Glu Gly Phe Gly His Leu Ser Pro Thr Gly Thr Thr Glu Phe Trp Leu
1 5 10 15
Gly Asn Glu Lys
20
<210> 1043
<211> 35
<212> PRT
<213> Homo sapiens
<400> 1043
Glu Gly Phe Gly His Leu Ser Pro Thr Gly Thr Thr Glu Phe Trp Leu
1 5 10 15
Gly Asn Glu Lys Ile His Leu Ile Ser Thr Gln Ser Ala Ile Pro Tyr
20 25 30
Ala Leu Arg
35
<210> 1044
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1044
Glu Gly Gly Pro Lys
1 5
<210> 1045
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1045
Glu Gly Gly Gln Thr Ala Pro Ala Ser Thr Arg
1 5 10
<210> 1046
<211> 31
<212> PRT
<213> Homo sapiens
<400> 1046
Glu Gly Ile Ser Gln Glu Ala Leu His Thr Gln Met Leu Thr Ala Val
1 5 10 15
Gln Glu Ile Ser His Leu Ile Glu Pro Leu Ala Asn Ala Ala Arg
20 25 30
<210> 1047
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1047
Glu Gly Ile Val Glu Tyr Pro Arg
1 5
<210> 1048
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1048
Glu Gly Lys Pro Tyr Leu Val Leu Gly Leu Leu Trp Gln Val Ile Lys
1 5 10 15
<210> 1049
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1049
Glu Gly Leu Glu Leu Leu Lys
1 5
<210> 1050
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1050
Glu Gly Met Leu Ser Ile Met Ser Tyr Arg
1 5 10
<210> 1051
<211> 29
<212> PRT
<213> Homo sapiens
<400> 1051
Glu Gly Asn Lys Pro Val Leu Phe Gln Gly Asn Thr Asn Pro Thr Asp
1 5 10 15
Val Val Val Ala Val Phe Pro Lys Pro Leu Ile Thr Arg
20 25
<210> 1052
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1052
Glu Gly Asn Pro Tyr Lys
1 5
<210> 1053
<211> 28
<212> PRT
<213> Homo sapiens
<400> 1053
Glu Gly Pro Pro Ser Glu His Ser Gly Thr Glu His Ala Ser Ala Ser
1 5 10 15
Ala Asn Gly His Val Ser Tyr Ser Ala Val Ser Arg
20 25
<210> 1054
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1054
Glu Gly Gln Met Glu Ser Val Glu Ala Ala Met Ser Ser Lys
1 5 10
<210> 1055
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1055
Glu Gly Thr Glu Thr Phe Ala Asp His Arg
1 5 10
<210> 1056
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1056
Glu Gly Thr Tyr His Phe Arg
1 5
<210> 1057
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1057
Glu Gly Val His Gly Gly Leu Ile Asn Lys
1 5 10
<210> 1058
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1058
Glu Gly Val His Gly Gly Leu Ile Asn Lys Lys
1 5 10
<210> 1059
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1059
Glu Gly Val Lys Phe Asp Glu Ser Glu Lys
1 5 10
<210> 1060
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1060
Glu Gly Val Val Ala Ala Ala Glu Lys
1 5
<210> 1061
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1061
Glu Gly Val Val His Gly Val Ala Thr Val Ala Glu Lys
1 5 10
<210> 1062
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1062
Glu Gly Trp Ile His Thr Val Cys Ile Asn Gly Arg
1 5 10
<210> 1063
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1063
Glu Gly Tyr Ser Asn Ile Ser Tyr Ile Val Val Asn His Gln Gly Ile
1 5 10 15
Ser Ser Arg
<210> 1064
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1064
Glu Gly Tyr Tyr Gly Tyr Thr Gly Ala Phe Arg
1 5 10
<210> 1065
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1065
Glu His Ala Val Glu Gly Asp Cys Asp Phe Gln Leu Leu Lys
1 5 10
<210> 1066
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1066
Glu His Ala Val Glu Gly Asp Cys Asp Phe Gln Leu Leu Lys Leu Asp
1 5 10 15
Gly Lys
<210> 1067
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1067
Glu His Glu Gly Ala Ile Tyr Pro Asp Asn Thr Thr Asp Phe Gln Arg
1 5 10 15
<210> 1068
<211> 21
<212> PRT
<213> Homo sapiens
<400> 1068
Glu His Gly Asp Pro Leu Ile Glu Glu Leu Asn Pro Gly Asp Ala Leu
1 5 10 15
Glu Pro Glu Gly Arg
20
<210> 1069
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1069
Glu His Ile Val Asp Leu Glu Met Leu Thr Val Ser Ser Ile Gly Thr
1 5 10 15
Phe Arg
<210> 1070
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1070
Glu His Leu Leu Met Ala Leu Ala Asp Leu Asp Glu Leu Leu Ile Arg
1 5 10 15
<210> 1071
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1071
Glu His Leu Leu Met Ala Leu Ala Gly Ile Asp Thr Leu Leu Ile Arg
1 5 10 15
<210> 1072
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1072
Glu His Leu Val Gln Ala Thr Pro Glu Asn Leu Gln Glu Ala Arg
1 5 10 15
<210> 1073
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1073
Glu His Met Gln Pro Thr His Pro Ile Arg
1 5 10
<210> 1074
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1074
Glu His Asn Leu Gln Val Leu Gly Leu Val Lys
1 5 10
<210> 1075
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1075
Glu His Ser Ser Leu Ala Phe Trp Lys
1 5
<210> 1076
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1076
Glu His Val Ala His Leu Leu Phe Leu Arg
1 5 10
<210> 1077
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1077
Glu His Val Ala His Leu Leu Phe Leu Arg Asp Thr Lys
1 5 10
<210> 1078
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1078
Glu His Val Thr Val Tyr Leu Gly Leu His Asp Val Arg
1 5 10
<210> 1079
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1079
Glu Ile Ala Glu Ala Tyr Leu Gly Lys
1 5
<210> 1080
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1080
Glu Ile Asp Tyr Lys
1 5
<210> 1081
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1081
Glu Ile Glu Ala Ser Lys
1 5
<210> 1082
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1082
Glu Ile Glu Glu Ile Arg
1 5
<210> 1083
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1083
Glu Ile Glu Glu Leu Arg
1 5
<210> 1084
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1084
Glu Ile Glu Met Ile Asn Glu Ser Glu Lys
1 5 10
<210> 1085
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1085
Glu Ile Glu Asn Gln Leu Arg
1 5
<210> 1086
<211> 23
<212> PRT
<213> Homo sapiens
<400> 1086
Glu Ile Glu Thr Tyr His Asn Leu Leu Glu Gly Gly Gln Glu Asp Phe
1 5 10 15
Glu Ser Ser Gly Ala Gly Lys
20
<210> 1087
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1087
Glu Ile Phe Asn Met Ala Arg
1 5
<210> 1088
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1088
Glu Ile Gly Glu Leu Tyr Leu Pro Lys
1 5
<210> 1089
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1089
Glu Ile Gly Glu Leu Tyr Leu Pro Lys Phe Ser Ile Ser Arg
1 5 10
<210> 1090
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1090
Glu Ile Ile Ile His Gln Asn Tyr Lys
1 5
<210> 1091
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1091
Glu Ile Ile Lys Pro Ala Glu Lys
1 5
<210> 1092
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1092
Glu Ile Ile Asn Val Gly His Ser Phe His Val Asn Phe Glu Asp Asn
1 5 10 15
Asp Asn Arg
<210> 1093
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1093
Glu Ile Ile Gln Glu Lys
1 5
<210> 1094
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1094
Glu Ile Ile Ser Gln Arg
1 5
<210> 1095
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1095
Glu Ile Ile Val Lys
1 5
<210> 1096
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1096
Glu Ile Lys Ile Glu Ile Ser Glu Leu Asn Arg
1 5 10
<210> 1097
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1097
Glu Ile Leu Ala Gly Lys
1 5
<210> 1098
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1098
Glu Ile Leu Ile Arg
1 5
<210> 1099
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1099
Glu Ile Leu Leu Arg
1 5
<210> 1100
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1100
Glu Ile Leu Asn Ile Asn Gln Lys
1 5
<210> 1101
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1101
Glu Ile Leu Asn Ser Leu Asp Lys
1 5
<210> 1102
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1102
Glu Ile Leu Val Lys
1 5
<210> 1103
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1103
Glu Ile Met Glu Asn Tyr Asn Ile Ala Leu Arg
1 5 10
<210> 1104
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1104
Glu Ile Asn Ile Ser Arg
1 5
<210> 1105
<211> 21
<212> PRT
<213> Homo sapiens
<400> 1105
Glu Ile Asn Leu Ala Pro Asp Ser Ser Ser Val Val Val Ser Gly Leu
1 5 10 15
Met Val Ala Thr Lys
20
<210> 1106
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1106
Glu Ile Asn Leu Gln Lys
1 5
<210> 1107
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1107
Glu Ile Asn Val Gln Lys
1 5
<210> 1108
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1108
Glu Ile Pro Ala Trp Val Pro Phe Asp Pro Ala Ala Gln Ile Thr Lys
1 5 10 15
<210> 1109
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1109
Glu Ile Pro Asp Glu Ile Ser Ile Leu Leu Leu Gly Val Ala His Phe
1 5 10 15
Lys
<210> 1110
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1110
Glu Ile Pro Glu Tyr Arg Lys
1 5
<210> 1111
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1111
Glu Ile Pro Val Leu Val Thr Gln Ile Ser Ser Thr Asn His Pro Val
1 5 10 15
Lys
<210> 1112
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1112
Glu Ile Pro Val Thr Val Tyr Lys Pro Ile Ile Lys
1 5 10
<210> 1113
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1113
Glu Ile Pro Val Thr Val Tyr Arg Pro Thr Leu Thr Lys
1 5 10
<210> 1114
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1114
Glu Ile Gln Ile Tyr Lys
1 5
<210> 1115
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1115
Glu Ile Gln Ile Tyr Lys Lys
1 5
<210> 1116
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1116
Glu Ile Gln Asn Ala Val Asn Gly Val Lys
1 5 10
<210> 1117
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1117
Glu Ile Gln Gln Arg
1 5
<210> 1118
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1118
Glu Ile Gln Thr Ala Val Arg
1 5
<210> 1119
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1119
Glu Ile Ser Leu Trp Phe Lys Pro Glu Glu Leu Val Asp Tyr Lys
1 5 10 15
<210> 1120
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1120
Glu Ile Thr Ala Leu Ala Pro Ser Thr Met Lys
1 5 10
<210> 1121
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1121
Glu Ile Thr Gln Glu Met Gln Thr Leu Lys
1 5 10
<210> 1122
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1122
Glu Ile Thr Val Ala Thr Gly Gly Phe Ile Tyr Thr Gly Glu Val Val
1 5 10 15
His Arg
<210> 1123
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1123
Glu Ile Val Leu Lys
1 5
<210> 1124
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1124
Glu Ile Val Leu Pro Lys
1 5
<210> 1125
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1125
Glu Lys Ala Glu Ala Gln Ala Gln Tyr Ser Ala Ala Val Ala Lys
1 5 10 15
<210> 1126
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1126
Glu Lys Ala Glu Gly Asp Val Ala Ala Leu Asn Arg
1 5 10
<210> 1127
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1127
Glu Lys Glu Leu Leu Ala Ala Lys
1 5
<210> 1128
<211> 24
<212> PRT
<213> Homo sapiens
<400> 1128
Glu Lys Phe Ser Asp Ala Ser Tyr Gln Ser Ile Asn Ile Pro Val Thr
1 5 10 15
Gln Asn Met Val Pro Ser Ser Arg
20
<210> 1129
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1129
Glu Lys Gly Glu Ile Gln Asn Ile Leu Gln Lys
1 5 10
<210> 1130
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1130
Glu Lys Leu Glu Ala Thr Ile Asn Glu Leu Val
1 5 10
<210> 1131
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1131
Glu Lys Leu Gln Asp Glu Asp Leu Gly Phe Leu
1 5 10
<210> 1132
<211> 24
<212> PRT
<213> Homo sapiens
<400> 1132
Glu Lys Pro Gln Ser Thr Ile Ser Gly Leu Leu Gly Pro Thr Leu Tyr
1 5 10 15
Ala Glu Val Gly Asp Ile Ile Lys
20
<210> 1133
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1133
Glu Leu Ala Ala Gln Ile Thr Lys
1 5
<210> 1134
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1134
Glu Leu Ala Ala Gln Thr Ile Lys
1 5
<210> 1135
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1135
Glu Leu Ala Ala Gln Thr Ile Lys Lys
1 5
<210> 1136
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1136
Glu Leu Ala Glu Glu Lys
1 5
<210> 1137
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1137
Glu Leu Ala Ile Leu Leu Gly Met Leu Asp Pro Ala Glu Lys Asp Glu
1 5 10 15
Lys
<210> 1138
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1138
Glu Leu Ala Asn Glu Ile Arg
1 5
<210> 1139
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1139
Glu Leu Ala Asn Glu Leu Arg
1 5
<210> 1140
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1140
Glu Leu Ala Asn Ile Leu Lys
1 5
<210> 1141
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1141
Glu Leu Ala Val Phe Arg
1 5
<210> 1142
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1142
Glu Leu Asp Arg Asp Thr Val Phe Ala Leu Val Asn Tyr Ile Phe Phe
1 5 10 15
Lys
<210> 1143
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1143
Glu Leu Asp Ser Thr Gly Thr Pro Thr Gly Lys
1 5 10
<210> 1144
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1144
Glu Leu Glu Ala Phe Arg
1 5
<210> 1145
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1145
Glu Leu Glu Ala Ser Lys
1 5
<210> 1146
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1146
Glu Leu Glu Glu Ile Arg
1 5
<210> 1147
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1147
Glu Leu Glu Glu Ile Val Gln Pro Ile Ile Ser Lys
1 5 10
<210> 1148
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1148
Glu Leu Glu Glu Leu Arg
1 5
<210> 1149
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1149
Glu Leu Glu Leu Gln Ile Gly Asn Ala Leu Phe Ile Gly Lys
1 5 10
<210> 1150
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1150
Glu Leu Glu Asn Ala Leu Lys
1 5
<210> 1151
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1151
Glu Leu Glu Ser Glu Val Asn Lys
1 5
<210> 1152
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1152
Glu Leu Phe Tyr Lys
1 5
<210> 1153
<211> 21
<212> PRT
<213> Homo sapiens
<400> 1153
Glu Leu Phe Tyr Lys Ala Asp Gly Glu Ser Cys Ser Ala Ser Met Met
1 5 10 15
Tyr Gln Glu Gly Lys
20
<210> 1154
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1154
Glu Leu Gly Cys Gly Ala Ala Ser Gly Thr Pro Ser Gly Ile Leu Tyr
1 5 10 15
Glu Pro Pro Ala Glu Lys Glu Gln Lys
20 25
<210> 1155
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1155
Glu Leu His His Leu Gln Glu Gln Asn Val Ser Asn Ala Phe Leu Asp
1 5 10 15
Lys
<210> 1156
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1156
Glu Leu His His Leu Gln Glu Gln Asn Val Ser Asn Ala Phe Leu Asp
1 5 10 15
Lys Gly Glu Phe Tyr Ile Gly Ser Lys
20 25
<210> 1157
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1157
Glu Leu Ile Glu Gln Leu Arg
1 5
<210> 1158
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1158
Glu Leu Ile Leu Arg
1 5
<210> 1159
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1159
Glu Leu Ile Ser Glu Arg Trp Lys
1 5
<210> 1160
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1160
Glu Leu Ile Ser Asn Ala Ser Asp Ala Leu Asp Lys
1 5 10
<210> 1161
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1161
Glu Leu Ile Ser Asn Ser Ser Asp Ala Leu Asp Lys
1 5 10
<210> 1162
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1162
Glu Leu Ile Val Lys
1 5
<210> 1163
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1163
Glu Leu Lys Glu Gln Gln Asp Ser Pro Gly Asn Lys
1 5 10
<210> 1164
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1164
Glu Leu Leu Ala Leu Ile Gln Leu Glu Arg
1 5 10
<210> 1165
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1165
Glu Leu Leu Asp Thr Val Thr Ala Pro Gln Lys
1 5 10
<210> 1166
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1166
Glu Leu Leu Glu Ser Tyr Ile Asp Gly Arg
1 5 10
<210> 1167
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1167
Glu Leu Leu Ile Arg
1 5
<210> 1168
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1168
Glu Leu Leu Leu Asp Leu Ala Lys
1 5
<210> 1169
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1169
Glu Leu Leu Leu Arg
1 5
<210> 1170
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1170
Glu Leu Leu Pro Val Leu Ile Ser Ala Met Lys
1 5 10
<210> 1171
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1171
Glu Leu Leu Val Lys
1 5
<210> 1172
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1172
Glu Leu Leu Val Pro Arg
1 5
<210> 1173
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1173
Glu Leu Met Glu Glu Lys
1 5
<210> 1174
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1174
Glu Leu Asn Glu Leu Gly Ser Lys
1 5
<210> 1175
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1175
Glu Leu Asn Glu Leu Gly Ser Lys Lys
1 5
<210> 1176
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1176
Glu Leu Asn Gln Ala Gly Gln Glu Thr Leu Val Thr Gly Trp Gly Tyr
1 5 10 15
His Ser Ser Arg
20
<210> 1177
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1177
Glu Leu Asn Tyr Lys
1 5
<210> 1178
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1178
Glu Leu Pro Glu His Thr Val Lys
1 5
<210> 1179
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1179
Glu Leu Pro Glu His Thr Val Lys Leu Cys Asp Asn Leu Ser Thr Lys
1 5 10 15
<210> 1180
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1180
Glu Leu Pro Pro His Leu Gly Glu Leu Thr Val Ala Glu Glu Thr Ser
1 5 10 15
Ser Ser Leu Arg
20
<210> 1181
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1181
Glu Leu Pro Gln Ser Ile Val Tyr Lys
1 5
<210> 1182
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1182
Glu Leu Pro Ser Phe Leu Gly Lys
1 5
<210> 1183
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1183
Glu Leu Pro Ser Leu Gln His Pro Asn Glu Gln Lys
1 5 10
<210> 1184
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1184
Glu Leu Gln Ala Ala Gln Ala Arg
1 5
<210> 1185
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1185
Glu Leu Gln Ala His Gly Ala Asp Glu Leu Leu Lys
1 5 10
<210> 1186
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1186
Glu Leu Gln Glu Leu Val Gln Tyr Pro Val Glu His Pro Asp Lys
1 5 10 15
<210> 1187
<211> 26
<212> PRT
<213> Homo sapiens
<400> 1187
Glu Leu Gln Lys Pro Asp Ser Phe His Ser Leu Thr Pro Thr Phe Ala
1 5 10 15
Ala Val Leu Val His Ile Asp Asn Leu Arg
20 25
<210> 1188
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1188
Glu Leu Gln Gln Arg
1 5
<210> 1189
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1189
Glu Leu Gln Val Tyr Ile Ser Pro Lys
1 5
<210> 1190
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1190
Glu Leu Arg Pro Trp Cys Phe Thr Thr Asp Pro Asn Lys
1 5 10
<210> 1191
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1191
Glu Leu Arg Pro Trp Cys Phe Thr Thr Asp Pro Asn Lys Arg
1 5 10
<210> 1192
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1192
Glu Leu Ser Asp Ile Ala His Arg
1 5
<210> 1193
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1193
Glu Leu Ser His Leu Pro Ser Leu Tyr Asp Tyr Ser Ala Tyr Arg
1 5 10 15
<210> 1194
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1194
Glu Leu Ser His Leu Pro Ser Leu Tyr Asp Tyr Ser Ala Tyr Arg Arg
1 5 10 15
<210> 1195
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1195
Glu Leu Ser Ser Phe Ile Asp Lys
1 5
<210> 1196
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1196
Glu Leu Ser Tyr Tyr Ser Leu Glu Asp Leu Asn Asn Lys
1 5 10
<210> 1197
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1197
Glu Leu Thr Glu Glu Lys
1 5
<210> 1198
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1198
Glu Leu Thr Ile Gly Ser Lys
1 5
<210> 1199
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1199
Glu Leu Thr Leu Glu Asp Leu Lys
1 5
<210> 1200
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1200
Glu Leu Thr Pro Glu Val Leu Gln Glu Trp Leu Asp Glu Leu Glu Glu
1 5 10 15
Met Met Leu Val Val His Met Pro Arg
20 25
<210> 1201
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1201
Glu Leu Thr Pro Gln Val Val Ser Ala Ala Arg
1 5 10
<210> 1202
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1202
Glu Leu Thr Thr Glu Ile Asp Asn Asn Ile Glu Gln Ile Ser Ser Tyr
1 5 10 15
Lys
<210> 1203
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1203
Glu Leu Val Ala Gln Gly Lys
1 5
<210> 1204
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1204
Glu Leu Val Ile Lys
1 5
<210> 1205
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1205
Glu Leu Val Leu Ala Gly Asn Arg
1 5
<210> 1206
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1206
Glu Leu Val Leu Lys
1 5
<210> 1207
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1207
Glu Leu Val Asn Met Ile Leu Met Lys
1 5
<210> 1208
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1208
Glu Met Glu Ala Glu Leu Glu Asp Glu Arg Lys
1 5 10
<210> 1209
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1209
Glu Met Glu Asp Thr Leu Asn His Leu Lys
1 5 10
<210> 1210
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1210
Glu Met Gln Pro Thr His Pro Ile Arg
1 5
<210> 1211
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1211
Glu Met Ser Gly Ser Pro Ala Ser Gly Ile Pro Val Lys
1 5 10
<210> 1212
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1212
Glu Asn Ala Asp Ser Leu Gln Ala Ser Leu Arg Pro His Ala Asp Glu
1 5 10 15
Leu Lys
<210> 1213
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1213
Glu Asn Ala Gly Glu Asp Pro Gly Leu Ala Arg
1 5 10
<210> 1214
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1214
Glu Asn Ala Leu Met Pro Asn Trp Leu His Leu Pro Val Gly Tyr His
1 5 10 15
Gly Arg
<210> 1215
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1215
Glu Asn Glu Arg Phe Gln Tyr Lys
1 5
<210> 1216
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1216
Glu Asn Phe Ala Gly Glu Ala Thr Leu Gln Arg
1 5 10
<210> 1217
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1217
Glu Asn Phe Asp Lys
1 5
<210> 1218
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1218
Glu Asn Phe Leu Phe Leu Thr Pro Asp Cys Lys
1 5 10
<210> 1219
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1219
Glu Asn Phe Gln Asn Trp Leu Lys
1 5
<210> 1220
<211> 24
<212> PRT
<213> Homo sapiens
<400> 1220
Glu Asn Ile Gln Asp Asn Ile Ser Leu Phe Ser Leu Gly Met Gly Phe
1 5 10 15
Asp Val Asp Tyr Asp Phe Leu Lys
20
<210> 1221
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1221
Glu Asn Ile Gln Asp Asn Ile Ser Leu Phe Ser Leu Gly Met Gly Phe
1 5 10 15
Asp Val Asp Tyr Asp Phe Leu Lys Arg
20 25
<210> 1222
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1222
Glu Asn Leu Asp Arg Asp Ile Ala Leu Met Lys
1 5 10
<210> 1223
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1223
Glu Asn Leu Leu Asp Phe Ile Lys
1 5
<210> 1224
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1224
Glu Asn Pro Leu Thr Gln Ala Val Pro Lys
1 5 10
<210> 1225
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1225
Glu Asn Gln Leu Glu Val Leu Glu Val Ser Trp Leu His Gly Leu Lys
1 5 10 15
<210> 1226
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1226
Glu Asn Ser Leu Tyr Leu Thr Ala Phe Thr Val Ile Gly Ile Arg
1 5 10 15
<210> 1227
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1227
Glu Asn Ser Leu Tyr Leu Thr Ala Phe Thr Val Ile Gly Ile Arg Lys
1 5 10 15
<210> 1228
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1228
Glu Asn Ser Gln Tyr Gln Pro Ile Lys
1 5
<210> 1229
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1229
Glu Asn Ser Gln Tyr Gln Pro Ile Lys Leu Gln Gly Thr Leu Pro Val
1 5 10 15
Glu Ala Arg
<210> 1230
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1230
Glu Pro Ala Asp Ala Ala Ile Arg
1 5
<210> 1231
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1231
Glu Pro Ala His Leu Met Ser Leu Phe Gly Gly Lys Pro Met Ile Ile
1 5 10 15
Tyr Lys
<210> 1232
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1232
Glu Pro Cys Val Glu Ser Leu Val Ser Gln Tyr Phe Gln Thr Val Thr
1 5 10 15
Asp Tyr Gly Lys
20
<210> 1233
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1233
Glu Pro Phe Glu Glu Lys
1 5
<210> 1234
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1234
Glu Pro Gly Glu Gly Leu Ala Val Thr Val Ser Leu Ile Gly Ala Tyr
1 5 10 15
Lys
<210> 1235
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1235
Glu Pro Gly Leu Gln Ile Trp Arg
1 5
<210> 1236
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1236
Glu Pro Gln Asp Thr Tyr His Tyr Leu Pro Phe Ser Leu Pro His Arg
1 5 10 15
<210> 1237
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1237
Glu Pro Gln Gln Arg Leu Asn Ile Lys
1 5
<210> 1238
<211> 32
<212> PRT
<213> Homo sapiens
<400> 1238
Glu Pro Val Ala Glu Pro Asp Ile Met Ala Thr Asn Gly Val Val His
1 5 10 15
Val Ile Thr Asn Val Leu Gln Pro Pro Ala Asn Arg Pro Gln Glu Arg
20 25 30
<210> 1239
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1239
Glu Pro Val Phe Arg
1 5
<210> 1240
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1240
Glu Gln Ala Asp Phe Ala Ile Glu Ala Leu Ala Lys
1 5 10
<210> 1241
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1241
Glu Gln Ala Asp Phe Ala Leu Glu Ala Leu Ala Lys
1 5 10
<210> 1242
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1242
Glu Gln Ala Phe Leu Thr Tyr His Met Lys
1 5 10
<210> 1243
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1243
Glu Gln Ala Pro His Cys Ile Cys Ala Asn Gly Arg
1 5 10
<210> 1244
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1244
Glu Gln Ala Pro Asn Leu Val Tyr Met Val Thr Gly Asn Pro Ala Ser
1 5 10 15
Asp Glu Ile Lys
20
<210> 1245
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1245
Glu Gln Ala Trp Gln Arg Pro Asp Gly Gln Pro Ala Thr Arg
1 5 10
<210> 1246
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1246
Glu Gln Asp Leu Glu Val Ile Leu His Asn Gly Ala Cys Ser Pro Gly
1 5 10 15
Ala Arg
<210> 1247
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1247
Glu Gln Glu Val Asn Ile Leu Lys
1 5
<210> 1248
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1248
Glu Gln Phe Leu Gln Gln Lys
1 5
<210> 1249
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1249
Glu Gln Gly Val Glu Glu His Glu Thr Leu Leu Leu Arg
1 5 10
<210> 1250
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1250
Glu Gln His Leu Phe Leu Pro Phe Ser Tyr Lys
1 5 10
<210> 1251
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1251
Glu Gln His Leu Gln Lys
1 5
<210> 1252
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1252
Glu Gln Leu Glu Glu Glu Glu Glu Ala Lys
1 5 10
<210> 1253
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1253
Glu Gln Leu Glu Leu Leu Lys
1 5
<210> 1254
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1254
Glu Gln Leu Gly Pro Val Thr Gln Glu Phe Trp Asp Asn Leu Glu Lys
1 5 10 15
<210> 1255
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1255
Glu Gln Leu Gly Pro Val Thr Gln Glu Phe Trp Asp Asn Leu Glu Lys
1 5 10 15
Glu Thr Glu Gly Leu Arg
20
<210> 1256
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1256
Glu Gln Leu Asn Leu Leu Ser Arg
1 5
<210> 1257
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1257
Glu Gln Leu Gln Asp Met Gly Leu Val Asp Leu Phe Ser Pro Glu Lys
1 5 10 15
<210> 1258
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1258
Glu Gln Leu Ser Leu Leu Asp Arg
1 5
<210> 1259
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1259
Glu Gln Leu Ser Leu Leu Asp Arg Phe Thr Glu Asp Ala Lys
1 5 10
<210> 1260
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1260
Glu Gln Leu Thr Pro Leu Ile Lys
1 5
<210> 1261
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1261
Glu Gln Pro Gly Val Tyr Thr Lys
1 5
<210> 1262
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1262
Glu Gln Pro Pro Ser Leu Thr Arg
1 5
<210> 1263
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1263
Glu Gln Gln Ala Leu Gln Thr Val Cys Leu Lys
1 5 10
<210> 1264
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1264
Glu Gln Gln Cys Val Ile Met Ala Glu Asn Arg
1 5 10
<210> 1265
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1265
Glu Gln Gln Cys Val Ile Met Ala Glu Asn Arg Lys
1 5 10
<210> 1266
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1266
Glu Gln Thr Met Ser Glu Cys Glu Ala Gly Ala Leu Arg
1 5 10
<210> 1267
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1267
Glu Gln Val Ala Glu Val Arg
1 5
<210> 1268
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1268
Glu Gln Val Gln Ser Cys Gly Pro Pro Pro Glu Leu Leu Asn Gly Asn
1 5 10 15
Val Lys
<210> 1269
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1269
Glu Gln Val Val Glu Asp Arg Pro Val Gly Gly Arg
1 5 10
<210> 1270
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1270
Glu Gln Trp Ile Leu Thr Ala Arg
1 5
<210> 1271
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1271
Glu Gln Tyr Ala Val Val Gly His Ser Ala His Ile Val Thr Leu Lys
1 5 10 15
<210> 1272
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1272
Glu Arg Glu Glu Tyr Val Leu Asn Asp Ile Gly Val Ile Phe Tyr Gly
1 5 10 15
Glu Val Asn Asp Ile Lys
20
<210> 1273
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1273
Glu Arg Glu Leu Glu Glu Ala Arg
1 5
<210> 1274
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1274
Glu Arg Gly Pro Glu Glu Glu His Leu Gly Ile Leu Gly Pro Val Ile
1 5 10 15
Trp Ala Glu Val Gly Asp Thr Ile Arg
20 25
<210> 1275
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1275
Glu Arg Pro Gly Val Tyr Thr Asn Val Val Glu Tyr Val Asp Trp Ile
1 5 10 15
Leu Glu Lys
<210> 1276
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1276
Glu Ser Ala Ser Leu Met Val Asp Arg
1 5
<210> 1277
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1277
Glu Ser Asp Glu Glu Thr Gln Ile Lys
1 5
<210> 1278
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1278
Glu Ser Asp Glu Glu Thr Gln Ile Lys Val Asn Trp Glu Glu Glu Ala
1 5 10 15
Ala Ser Gly Leu Leu Thr Ser Leu Lys
20 25
<210> 1279
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1279
Glu Ser Asp Thr Ser Tyr Val Ser Leu Lys
1 5 10
<210> 1280
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1280
Glu Ser Gly Met Thr Met Glu Glu Leu Lys
1 5 10
<210> 1281
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1281
Glu Ser Gly Pro Pro His Met Lys
1 5
<210> 1282
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1282
Glu Ser His Val Thr Leu Ala Ser Pro Glu Glu Thr Arg
1 5 10
<210> 1283
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1283
Glu Ser Ile Leu Phe His Tyr Thr Asp Trp Val Asp Asp Gln Arg Pro
1 5 10 15
Glu Asn Tyr Arg
20
<210> 1284
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1284
Glu Ser Ile Ser Val Ser Ser Glu Gln Leu Ala Gln Phe Arg
1 5 10
<210> 1285
<211> 27
<212> PRT
<213> Homo sapiens
<400> 1285
Glu Ser Ile Val Gln Val His Ile Glu Val Leu Asp Glu Asn Asp Asn
1 5 10 15
Ala Pro Glu Phe Ala Lys Pro Tyr Gln Pro Lys
20 25
<210> 1286
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1286
Glu Ser Lys Pro Leu Thr Ala Gln Gln Thr Thr Lys
1 5 10
<210> 1287
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1287
Glu Ser Leu Leu Asn His Phe Leu Tyr Glu Val Ala Arg
1 5 10
<210> 1288
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1288
Glu Ser Leu Ser Ser Tyr Trp Glu Ser Ala Lys
1 5 10
<210> 1289
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1289
Glu Ser Met Leu Lys
1 5
<210> 1290
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1290
Glu Ser Asn Thr Val Phe Ser Phe Leu Gly Leu Lys Pro Arg
1 5 10
<210> 1291
<211> 27
<212> PRT
<213> Homo sapiens
<400> 1291
Glu Ser Pro Gly Asn Val Gln Ile Val Asn Gly Tyr Phe Val His Phe
1 5 10 15
Phe Ala Pro Gln Gly Leu Pro Val Val Pro Lys
20 25
<210> 1292
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1292
Glu Ser Gln Leu Pro Thr Val Met Asp Phe Arg
1 5 10
<210> 1293
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1293
Glu Ser Gln Leu Pro Thr Val Met Asp Phe Arg Lys
1 5 10
<210> 1294
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1294
Glu Ser Ser Ser His His Pro Gly Ile Ala Glu Phe Pro Ser Arg
1 5 10 15
<210> 1295
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1295
Glu Ser Ser Ser His His Pro Gly Ile Ala Glu Phe Pro Ser Arg Gly
1 5 10 15
Lys
<210> 1296
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1296
Glu Ser Thr Leu His Leu Val Leu Arg
1 5
<210> 1297
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1297
Glu Ser Tyr Ser Gly Val Thr Leu Asp Pro Arg
1 5 10
<210> 1298
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1298
Glu Thr Ala Ala Ser Leu Leu Gln Ala Gly Tyr Lys
1 5 10
<210> 1299
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1299
Glu Thr Ala Val Asp Gly Glu Leu Val Val Leu Tyr Asp Val Lys
1 5 10 15
<210> 1300
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1300
Glu Thr Ala Val Asp Gly Glu Leu Val Val Leu Tyr Asp Val Lys Arg
1 5 10 15
<210> 1301
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1301
Glu Thr Ala Val Ser Thr Glu Asp Asp Ser His His Lys
1 5 10
<210> 1302
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1302
Glu Thr Asp Ile Glu Asp Ser Asp Asp Ile Pro Glu Asp Thr Thr Tyr
1 5 10 15
Lys Lys
<210> 1303
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1303
Glu Thr Glu Gly Leu Arg Gln Glu Met Ser Lys
1 5 10
<210> 1304
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1304
Glu Thr Glu Ser Ile Glu Lys
1 5
<210> 1305
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1305
Glu Thr Phe Asp Val Thr Leu Glu Pro Leu Ser Phe Lys
1 5 10
<210> 1306
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1306
Glu Thr Phe Asp Val Thr Leu Glu Pro Leu Ser Phe Lys Lys
1 5 10
<210> 1307
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1307
Glu Thr Gly Glu His Leu Val His Val Lys
1 5 10
<210> 1308
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1308
Glu Thr Ile Glu Leu Val His Thr Glu Pro Thr Asp Val Ala Gln Leu
1 5 10 15
Pro Ser Arg
<210> 1309
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1309
Glu Thr Ile Glu Gln Glu Lys
1 5
<210> 1310
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1310
Glu Thr Ile Val Leu Lys
1 5
<210> 1311
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1311
Glu Thr Leu Cys Lys
1 5
<210> 1312
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1312
Glu Thr Leu Glu Asp Thr Arg
1 5
<210> 1313
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1313
Glu Thr Leu Glu Asp Thr Arg Asp Arg
1 5
<210> 1314
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1314
Glu Thr Leu Phe Ser Val Met Pro Gly Leu Lys
1 5 10
<210> 1315
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1315
Glu Thr Leu Leu Gln Asp Phe Arg
1 5
<210> 1316
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1316
Glu Thr Leu Val Leu Lys
1 5
<210> 1317
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1317
Glu Thr Gln Ser Ile Glu Lys
1 5
<210> 1318
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1318
Glu Thr Ser Leu Thr Val Asn Lys
1 5
<210> 1319
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1319
Glu Thr Ser Asn Phe Gly Phe Ser Leu Leu Arg
1 5 10
<210> 1320
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1320
Glu Thr Thr Phe Asn Ser Leu Leu Cys Pro Ser Gly Gly Glu Val Ser
1 5 10 15
Glu Glu Leu Ser Leu Lys
20
<210> 1321
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1321
Glu Thr Thr Leu Gly Asp Met Thr Gly Lys
1 5 10
<210> 1322
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1322
Glu Thr Thr Leu Ser Tyr Tyr Lys
1 5
<210> 1323
<211> 32
<212> PRT
<213> Homo sapiens
<400> 1323
Glu Thr Val Leu Thr Phe Ile Asp Pro Glu Gly Ser Glu Val Asp Met
1 5 10 15
Val Glu Glu Ile Asp His Ile Gly Ile Ile Ser Phe Pro Asp Phe Lys
20 25 30
<210> 1324
<211> 38
<212> PRT
<213> Homo sapiens
<400> 1324
Glu Thr Val Leu Thr Phe Ile Asp Pro Glu Gly Ser Glu Val Asp Met
1 5 10 15
Val Glu Glu Ile Asp His Ile Gly Ile Ile Ser Phe Pro Asp Phe Lys
20 25 30
Ile Pro Ser Asn Pro Arg
35
<210> 1325
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1325
Glu Thr Val Gln Thr Thr Glu Asp Gln Ile Leu Lys Arg
1 5 10
<210> 1326
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1326
Glu Thr Trp Thr Ala Asn Val Gly Lys
1 5
<210> 1327
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1327
Glu Val Ala Phe Asp Leu Glu Ile Pro Lys
1 5 10
<210> 1328
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1328
Glu Val Ala Leu Asp Leu Ser Gln His Lys
1 5 10
<210> 1329
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1329
Glu Val Ala Asn Ser Thr Ala Asn Leu Val Lys
1 5 10
<210> 1330
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1330
Glu Val Asp Ile Lys
1 5
<210> 1331
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1331
Glu Val Asp Leu Lys
1 5
<210> 1332
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1332
Glu Val Asp Leu Lys Asp Tyr Glu Asp Gln Gln Lys
1 5 10
<210> 1333
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1333
Glu Val Glu Glu Asp Glu Tyr Lys
1 5
<210> 1334
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1334
Glu Val Glu Ile Arg Glu Glu
1 5
<210> 1335
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1335
Glu Val Glu Asn Ser Glu Asp Pro Lys
1 5
<210> 1336
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1336
Glu Val Glu Asn Ser Glu Asp Pro Lys Phe Arg
1 5 10
<210> 1337
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1337
Glu Val Phe Asn Ile Leu Gln Ala Ala Tyr Val Ser Lys Pro Gly Ala
1 5 10 15
Gln Leu Ala Arg
20
<210> 1338
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1338
Glu Val Phe Val His Pro Asn Tyr Ser Lys
1 5 10
<210> 1339
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1339
Glu Val Gly Pro Pro Leu Pro Gln Glu Ala Val Pro Leu Gln Lys
1 5 10 15
<210> 1340
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1340
Glu Val Gly Pro Thr Asn Ala Asp Pro Val Cys Leu Ala Lys
1 5 10
<210> 1341
<211> 24
<212> PRT
<213> Homo sapiens
<400> 1341
Glu Val Gly Thr Pro His Gly Ile Ile Leu Asp Ser Val Asp Ala Ala
1 5 10 15
Phe Ile Cys Pro Gly Ser Ser Arg
20
<210> 1342
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1342
Glu Val Gly Thr Val Leu Ser Gln Val Tyr Ser Lys
1 5 10
<210> 1343
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1343
Glu Val Ile Ala Val Tyr Gln Leu Phe Val Glu Thr Thr Asp Val Asn
1 5 10 15
Gly Lys
<210> 1344
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1344
Glu Val Ile Ile Thr Gly Ile Gln Thr Gln Gly Ala Lys
1 5 10
<210> 1345
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1345
Glu Val Ile Gln Glu Trp Asn Leu Thr Asn Ile Lys
1 5 10
<210> 1346
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1346
Glu Val Ile Gln Glu Trp Asn Leu Thr Asn Ile Lys Arg
1 5 10
<210> 1347
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1347
Glu Val Leu Leu Pro Lys
1 5
<210> 1348
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1348
Glu Val Leu Tyr Glu Leu Ile Glu Lys
1 5
<210> 1349
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1349
Glu Val Leu Tyr Lys
1 5
<210> 1350
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1350
Glu Val Asn Ile Asn Lys
1 5
<210> 1351
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1351
Glu Val Pro Cys Ala Ser Val Lys
1 5
<210> 1352
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1352
Glu Val Pro Leu Asn Thr Ile Ile Phe Met Gly Arg
1 5 10
<210> 1353
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1353
Glu Val Gln Gly Phe Glu Ser Ala Thr Phe Leu Gly Tyr Phe Lys
1 5 10 15
<210> 1354
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1354
Glu Val Ser Phe Asp Val Glu Leu Pro Lys
1 5 10
<210> 1355
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1355
Glu Val Thr Val Leu Leu Glu His Gln Lys
1 5 10
<210> 1356
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1356
Glu Val Val Ala Asp Ser Val Trp Val Asp Val Lys
1 5 10
<210> 1357
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1357
Glu Val Val Asp Trp Arg
1 5
<210> 1358
<211> 32
<212> PRT
<213> Homo sapiens
<400> 1358
Glu Val Val Pro Arg Pro Arg Pro Gly Val Thr Glu Ala Thr Ile Thr
1 5 10 15
Gly Leu Glu Pro Gly Thr Glu Tyr Thr Ile Tyr Val Ile Ala Leu Lys
20 25 30
<210> 1359
<211> 30
<212> PRT
<213> Homo sapiens
<400> 1359
Glu Val Val Thr Ser Glu Asp Gly Ser Asp Cys Pro Glu Ala Met Asp
1 5 10 15
Leu Gly Thr Leu Ser Gly Ile Gly Thr Leu Asp Gly Phe Arg
20 25 30
<210> 1360
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1360
Glu Val Tyr Gly Phe Asn Pro Glu Gly Lys
1 5 10
<210> 1361
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1361
Glu Val Tyr Ile Lys
1 5
<210> 1362
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1362
Glu Val Tyr Ile Lys Asn Gly Asp Lys
1 5
<210> 1363
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1363
Glu Val Tyr Met Pro Ser Ser Ile Phe Gln Asp Asp Phe Val Ile Pro
1 5 10 15
Asp Ile Ser Glu Pro Gly Thr Trp Lys
20 25
<210> 1364
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1364
Glu Trp Glu Ile Val Asn Gln Asp Asn His Tyr Ser Pro His Phe Gln
1 5 10 15
Glu Ile Arg
<210> 1365
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1365
Glu Trp Phe Ser Glu Thr Phe Gln Lys
1 5
<210> 1366
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1366
Glu Trp Phe Trp Asp Leu Ala Thr Gly Thr Met Lys
1 5 10
<210> 1367
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1367
Glu Trp Tyr Glu Lys
1 5
<210> 1368
<211> 27
<212> PRT
<213> Homo sapiens
<400> 1368
Glu Tyr Ala Asn Gln Phe Met Trp Glu Tyr Ser Thr Asn Tyr Gly Gln
1 5 10 15
Ala Pro Leu Ser Leu Leu Val Ser Tyr Thr Lys
20 25
<210> 1369
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1369
Glu Tyr Ala Pro Gly Glu Thr Val Lys
1 5
<210> 1370
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1370
Glu Tyr Ala Val Lys
1 5
<210> 1371
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1371
Glu Tyr Glu Met Lys
1 5
<210> 1372
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1372
Glu Tyr Glu Pro Tyr Phe Lys
1 5
<210> 1373
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1373
Glu Tyr Phe Ala Ile Asp Asn Ser Gly Arg
1 5 10
<210> 1374
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1374
Glu Tyr Phe Ser Lys
1 5
<210> 1375
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1375
Glu Tyr Gly Lys Ser Leu Asn Ser Lys
1 5
<210> 1376
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1376
Glu Tyr His Phe Gly Gln Ala Val Arg
1 5
<210> 1377
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1377
Glu Tyr His Thr Glu Lys
1 5
<210> 1378
<211> 35
<212> PRT
<213> Homo sapiens
<400> 1378
Glu Tyr Leu Ile Met Gly Leu Asp Gly Ala Thr Tyr Asp Leu Glu Gly
1 5 10 15
His Pro Gln Tyr Leu Leu Asp Ser Asn Ser Trp Ile Glu Glu Met Pro
20 25 30
Ser Glu Arg
35
<210> 1379
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1379
Glu Tyr Gln Thr Arg
1 5
<210> 1380
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1380
Glu Tyr Ser Gly Thr Ile Ala Ser Glu Ala Asn Thr Tyr Leu Asn Ser
1 5 10 15
Lys
<210> 1381
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1381
Glu Tyr Thr Asp Ala Ser Phe Thr Asn Arg
1 5 10
<210> 1382
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1382
Glu Tyr Thr Asp Ala Ser Phe Thr Asn Arg Lys
1 5 10
<210> 1383
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1383
Glu Tyr Thr Asn Ile Phe Leu Lys
1 5
<210> 1384
<211> 21
<212> PRT
<213> Homo sapiens
<400> 1384
Glu Tyr Val Leu Pro His Phe Ser Val Ser Ile Glu Pro Glu Tyr Asn
1 5 10 15
Phe Ile Gly Tyr Lys
20
<210> 1385
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1385
Glu Tyr Val Leu Pro Ser Phe Glu Val Ile Val Glu Pro Thr Glu Lys
1 5 10 15
<210> 1386
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1386
Glu Tyr Tyr Phe Ala Glu Ala Gln Ile Ala Asp Phe Ser Asp Pro Ala
1 5 10 15
Phe Ile Ser Lys
20
<210> 1387
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1387
Phe Ala Ala Phe Ile Asp Lys
1 5
<210> 1388
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1388
Phe Ala Cys Tyr Tyr Pro Arg
1 5
<210> 1389
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1389
Phe Ala Asp Gln His Val Pro Gly Ser Pro Phe Ser Val Lys
1 5 10
<210> 1390
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1390
Phe Ala Glu Glu Asp Lys Lys
1 5
<210> 1391
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1391
Phe Ala Phe Asn Leu Tyr Arg
1 5
<210> 1392
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1392
Phe Ala Gly Val Phe His Val Glu Lys
1 5
<210> 1393
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1393
Phe Ala His Asn Val Val Thr Met Arg
1 5
<210> 1394
<211> 31
<212> PRT
<213> Homo sapiens
<400> 1394
Phe Ala His Thr Asn Val Glu Ser Leu Val Asn Glu Tyr Asp Asp Asn
1 5 10 15
Gly Glu Gly Ile Ile Leu Phe Arg Pro Ser His Leu Thr Asn Lys
20 25 30
<210> 1395
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1395
Phe Ala His Thr Val Val Thr Ser Arg
1 5
<210> 1396
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1396
Phe Ala His Tyr Val Val Thr Ser Gln Val Val Asn Thr Ala Asn Glu
1 5 10 15
Ala Arg
<210> 1397
<211> 23
<212> PRT
<213> Homo sapiens
<400> 1397
Phe Ala Leu Pro Ser Pro Gln His Ile Leu Gly Leu Pro Val Gly Gln
1 5 10 15
His Ile Tyr Leu Ser Ala Arg
20
<210> 1398
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1398
Phe Ala Pro Val Val Ala Pro Lys Pro Lys
1 5 10
<210> 1399
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1399
Phe Ala Ser Phe Ile Asp Lys
1 5
<210> 1400
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1400
Phe Ala Ser Phe Ile Asp Lys Val Arg
1 5
<210> 1401
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1401
Phe Ala Ser Gly Lys
1 5
<210> 1402
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1402
Phe Ala Ser Ser Lys
1 5
<210> 1403
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1403
Phe Ala Ser Thr Phe Asp Lys
1 5
<210> 1404
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1404
Phe Ala Thr Thr Phe Tyr Gln His Leu Ala Asp Ser Lys
1 5 10
<210> 1405
<211> 34
<212> PRT
<213> Homo sapiens
<400> 1405
Phe Ala Thr Thr Phe Tyr Gln His Leu Ala Asp Ser Lys Asn Asp Asn
1 5 10 15
Asp Asn Ile Phe Leu Ser Pro Leu Ser Ile Ser Thr Ala Phe Ala Met
20 25 30
Thr Lys
<210> 1406
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1406
Phe Cys Glu Asn Pro Asp Glu Val Lys Arg
1 5 10
<210> 1407
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1407
Phe Cys Gly Gln Leu Gly Ser Pro Leu Gly Asn Pro Pro Gly Lys
1 5 10 15
<210> 1408
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1408
Phe Cys Gly Gln Leu Gly Ser Pro Leu Gly Asn Pro Pro Gly Lys Lys
1 5 10 15
<210> 1409
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1409
Phe Asp Glu Phe Phe Ser Glu Gly Cys Ala Pro Gly Ser Lys Lys
1 5 10 15
<210> 1410
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1410
Phe Asp Glu His Gln Ser Lys Pro Glu Ile Leu Asn Leu Val Lys
1 5 10 15
<210> 1411
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1411
Phe Asp Glu Ser Glu Lys
1 5
<210> 1412
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1412
Phe Asp His Thr Asn Ser Leu Asn Ile Ala Gly Leu Ser Leu Asp Phe
1 5 10 15
Ser Ser Lys
<210> 1413
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1413
Phe Asp His Val Ile Thr Asn Met Asn Asn Asn Tyr Glu Pro Arg
1 5 10 15
<210> 1414
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1414
Phe Asp Leu Glu Val Lys
1 5
<210> 1415
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1415
Phe Asp Pro Ala Lys
1 5
<210> 1416
<211> 39
<212> PRT
<213> Homo sapiens
<400> 1416
Phe Asp Pro Ala Lys Leu Asp Gln Ile Glu Ser Val Ile Thr Ala Thr
1 5 10 15
Ser Ala Asn Thr Gln Leu Val Leu Glu Thr Leu Ala Gln Met Asp Asp
20 25 30
Leu Gln Asp Phe Leu Ser Lys
35
<210> 1417
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1417
Phe Asp Pro Ser Leu Thr Gln Arg
1 5
<210> 1418
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1418
Phe Asp Pro Val Arg
1 5
<210> 1419
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1419
Phe Asp Pro Val Arg Gly Glu Val Pro Pro Arg
1 5 10
<210> 1420
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1420
Phe Asp Thr Ile Ser Glu Lys
1 5
<210> 1421
<211> 32
<212> PRT
<213> Homo sapiens
<400> 1421
Phe Asp Val Ser Ser Phe Asn Pro His Gly Ile Ser Thr Phe Thr Asp
1 5 10 15
Glu Asp Asn Ala Met Tyr Leu Leu Val Val Asn His Pro Asp Ala Lys
20 25 30
<210> 1422
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1422
Phe Glu Asp Glu Asn Phe Ile Leu Lys
1 5
<210> 1423
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1423
Phe Glu Asp Gly Val Leu Asp Pro Asp Tyr Pro Arg
1 5 10
<210> 1424
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1424
Phe Glu Glu Gln Gln Lys
1 5
<210> 1425
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1425
Phe Glu Gly Ile Ala Cys Glu Ile Ser Lys
1 5 10
<210> 1426
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1426
Phe Glu Gly Asn Cys Ala Glu Gln Asp Gly Ser Gly Trp Trp Met Asn
1 5 10 15
Lys
<210> 1427
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1427
Phe Glu Gln Leu Glu Leu Arg Pro Val Leu Tyr Asn Tyr Leu Asp Lys
1 5 10 15
<210> 1428
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1428
Phe Glu Arg Asp Gln Glu Lys
1 5
<210> 1429
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1429
Phe Glu Thr Val His Gln Ile His Lys
1 5
<210> 1430
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1430
Phe Glu Val Gln Val Thr Val Pro Lys
1 5
<210> 1431
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1431
Phe Phe Glu Ser Phe Gly Asp Leu Ser Thr Pro Asp Ala Val Met Gly
1 5 10 15
Asn Pro Lys
<210> 1432
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1432
Phe Phe Gly Glu Gly Thr Lys
1 5
<210> 1433
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1433
Phe Phe Gly Glu Gly Thr Lys Lys
1 5
<210> 1434
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1434
Phe Phe Gly His Gly Ala Glu Asp Ser Leu Ala Asp Gln Ala Ala Asn
1 5 10 15
Glu Trp Gly Arg
20
<210> 1435
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1435
Phe Phe His Lys Asn Glu Ile Trp Tyr Arg
1 5 10
<210> 1436
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1436
Phe Phe Leu Ser His Pro Ala Tyr Arg
1 5
<210> 1437
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1437
Phe Phe Leu Thr Asn Gly Glu Ile Met Thr Phe Glu Lys
1 5 10
<210> 1438
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1438
Phe Phe Asn Val Leu Thr Thr Asn Thr Asp Gly Lys
1 5 10
<210> 1439
<211> 23
<212> PRT
<213> Homo sapiens
<400> 1439
Phe Phe Asn Val Leu Thr Thr Asn Thr Asp Gly Lys Ile Glu Phe Ile
1 5 10 15
Ser Thr Met Glu Gly Tyr Lys
20
<210> 1440
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1440
Phe Phe Ser Ala Gln Thr Asn Arg
1 5
<210> 1441
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1441
Phe Phe Thr Arg Glu Pro Gln Asp Thr Tyr His Tyr Leu Pro Phe Ser
1 5 10 15
Leu Pro His Arg
20
<210> 1442
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1442
Phe Phe Thr Ser His Asn Gly Met Gln Phe Ser Thr Trp Asp Asn Asp
1 5 10 15
Asn Asp Lys
<210> 1443
<211> 36
<212> PRT
<213> Homo sapiens
<400> 1443
Phe Phe Thr Ser His Asn Gly Met Gln Phe Ser Thr Trp Asp Asn Asp
1 5 10 15
Asn Asp Lys Phe Glu Gly Asn Cys Ala Glu Gln Asp Gly Ser Gly Trp
20 25 30
Trp Met Asn Lys
35
<210> 1444
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1444
Phe Phe Val Gly Gly Asn Trp Lys
1 5
<210> 1445
<211> 21
<212> PRT
<213> Homo sapiens
<400> 1445
Phe Gly Ala Val Phe Leu Trp Asp Ser Gly Ser Ser Val Gly Glu Ile
1 5 10 15
Thr Gly His Asn Lys
20
<210> 1446
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1446
Phe Gly Cys Phe Leu Lys
1 5
<210> 1447
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1447
Phe Gly Gly Gly Lys
1 5
<210> 1448
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1448
Phe Gly Gly Leu Glu Gly Leu Lys
1 5
<210> 1449
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1449
Phe Gly Gly Val Leu His Leu Ser Asp Leu Asp Asp Asp Gly Leu Asp
1 5 10 15
Glu Ile Ile Met Ala Ala Pro Leu Arg
20 25
<210> 1450
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1450
Phe Gly His Thr Leu Val Asn Pro Leu Leu Tyr Arg
1 5 10
<210> 1451
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1451
Phe Gly Leu Phe Ala Pro Ile His Lys
1 5
<210> 1452
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1452
Phe Gly Leu Phe Lys Pro Gly Glu Ile Ala Pro Leu Leu Phe Arg
1 5 10 15
<210> 1453
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1453
Phe Gly Leu Leu Asp Glu Asp Gly Lys
1 5
<210> 1454
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1454
Phe Gly Leu Leu Asp Glu Asp Gly Lys Lys
1 5 10
<210> 1455
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1455
Phe Gly Met His Leu Gln Ala Ala Thr Pro Lys
1 5 10
<210> 1456
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1456
Phe Gly Pro Val Val Ala Pro Lys Pro Lys
1 5 10
<210> 1457
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1457
Phe Gly Gln Gly Ala His His Ala Ala Gly Gln Ala Gly Asn Glu Ala
1 5 10 15
Gly Arg
<210> 1458
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1458
Phe Gly Gln Gly Val His His Ala Ala Gly Gln Ala Gly Asn Glu Ala
1 5 10 15
Gly Arg
<210> 1459
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1459
Phe Gly Gln Gly Val His His Thr Ala Gly Gln Val Gly Lys
1 5 10
<210> 1460
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1460
Phe Gly Gln Thr Pro Val Gln Glu Arg
1 5
<210> 1461
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1461
Phe Gly Ser Gly Tyr Val Ser Gly Trp Gly Arg
1 5 10
<210> 1462
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1462
Phe Gly Ser Pro Lys
1 5
<210> 1463
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1463
Phe Gly Ser Ser Leu Ile Thr Val Arg
1 5
<210> 1464
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1464
Phe Gly Val Pro Ser Pro Ser Thr Leu Glu Pro His Pro Arg Pro Leu
1 5 10 15
Leu Gln Arg
<210> 1465
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1465
Phe His Asp Phe Leu Gly Asp Ser Trp Gly Ile Leu Phe Ser His Pro
1 5 10 15
Arg
<210> 1466
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1466
Phe His His Thr Phe Ser Thr Glu Ile Ala Lys
1 5 10
<210> 1467
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1467
Phe His Ile Leu Phe Lys
1 5
<210> 1468
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1468
Phe His Ile Pro Ser Ser Val Pro Tyr Ile Arg
1 5 10
<210> 1469
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1469
Phe His Pro Leu His Ser Lys
1 5
<210> 1470
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1470
Phe His Ser Phe Pro Asn Val Tyr His Glu Leu Ser Lys
1 5 10
<210> 1471
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1471
Phe His Val Glu Glu Glu Gly Lys
1 5
<210> 1472
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1472
Phe His Val Pro Asn Val Thr Pro Tyr Ile Arg
1 5 10
<210> 1473
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1473
Phe Ile Ala Glu Ser Lys
1 5
<210> 1474
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1474
Phe Ile Cys Pro Leu Thr Gly Leu Trp Pro Ile Asn Thr Leu Lys
1 5 10 15
<210> 1475
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1475
Phe Ile Glu Asp Val Lys
1 5
<210> 1476
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1476
Phe Ile Ile Glu Gly Met Glu Glu Ala Gly Ser Val Ala Leu Glu Glu
1 5 10 15
Leu Val Glu Lys
20
<210> 1477
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1477
Phe Ile Ile Glu Gly Met Glu Glu Ala Gly Ser Val Ala Leu Glu Glu
1 5 10 15
Leu Val Glu Lys Glu Lys
20
<210> 1478
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1478
Phe Ile Ile Pro Gly Leu Lys
1 5
<210> 1479
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1479
Phe Ile Ile Pro Asn Val Val Lys
1 5
<210> 1480
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1480
Phe Ile Ile Pro Gln Ile Val Lys
1 5
<210> 1481
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1481
Phe Ile Ile Pro Ser Pro Lys
1 5
<210> 1482
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1482
Phe Ile Leu Ser Arg
1 5
<210> 1483
<211> 27
<212> PRT
<213> Homo sapiens
<400> 1483
Phe Ile Asn Asp Tyr Gly Thr His Tyr Ile Thr Ser Gly Ser Met Gly
1 5 10 15
Gly Ile Tyr Glu Tyr Ile Leu Val Ile Asp Lys
20 25
<210> 1484
<211> 29
<212> PRT
<213> Homo sapiens
<400> 1484
Phe Ile Asn Asp Tyr Gly Thr His Tyr Ile Thr Ser Gly Ser Met Gly
1 5 10 15
Gly Ile Tyr Glu Tyr Ile Leu Val Ile Asp Lys Ala Lys
20 25
<210> 1485
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1485
Phe Ile Gln Val Gly Val Ile Ser Trp Gly Val Val Asp Val Cys Lys
1 5 10 15
<210> 1486
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1486
Phe Ile Thr Ile Phe Gly Thr Arg
1 5
<210> 1487
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1487
Phe Ile Tyr Val Ala Ile Ala Gln Phe Ile Glu Thr Thr Lys
1 5 10
<210> 1488
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1488
Phe Lys Asp Leu Gly Glu Glu Asn Phe Lys
1 5 10
<210> 1489
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1489
Phe Lys Lys Pro Gln Ser Leu Thr Lys
1 5
<210> 1490
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1490
Phe Lys Leu Asp Asp Asp Leu Glu His Gln Gly Gly His Val Leu Asp
1 5 10 15
His Gly His Lys
20
<210> 1491
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1491
Phe Lys Leu Asp Gln Lys
1 5
<210> 1492
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1492
Phe Lys Leu Glu Lys
1 5
<210> 1493
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1493
Phe Lys Asn Gly Met Leu His Gly Asp Lys
1 5 10
<210> 1494
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1494
Phe Lys Asn Ser Leu Leu Gln Lys
1 5
<210> 1495
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1495
Phe Lys Pro Gln Ser Leu Pro Asp His Lys
1 5 10
<210> 1496
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1496
Phe Lys Pro Thr Leu Ser Gln Gln Gln Lys
1 5 10
<210> 1497
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1497
Phe Lys Thr Gly Thr Thr Leu Lys
1 5
<210> 1498
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1498
Phe Leu Ala Glu Lys
1 5
<210> 1499
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1499
Phe Leu Ala Ser Val Ser Thr Val Leu Thr Ser Lys
1 5 10
<210> 1500
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1500
Phe Leu Ala Thr Thr Pro Asn Ser Leu Leu Val Ser Trp Gln Pro Pro
1 5 10 15
Arg
<210> 1501
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1501
Phe Leu Asp Ser Asn Ile Lys
1 5
<210> 1502
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1502
Phe Leu Glu Asp Val Lys
1 5
<210> 1503
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1503
Phe Leu Glu Asp Val Lys Lys
1 5
<210> 1504
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1504
Phe Leu Glu Asn Glu Asp Arg
1 5
<210> 1505
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1505
Phe Leu Glu Asn Glu Asp Arg Arg
1 5
<210> 1506
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1506
Phe Leu Glu Asn Leu Leu Glu Lys
1 5
<210> 1507
<211> 27
<212> PRT
<213> Homo sapiens
<400> 1507
Phe Leu Glu Pro Phe Asp Ile Asp Asp His Gln Gln Val His Cys Pro
1 5 10 15
Tyr Asp Gln Leu Gln Ile Tyr Ala Asn Gly Lys
20 25
<210> 1508
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1508
Phe Leu Glu Gln Gln Asn Gln Val Leu Gln Thr Lys
1 5 10
<210> 1509
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1509
Phe Leu Phe Asp Thr Lys
1 5
<210> 1510
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1510
Phe Leu Phe Asp Thr Lys Glu Glu Ile Leu Met His Leu Trp Arg
1 5 10 15
<210> 1511
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1511
Phe Leu Phe Ser Arg
1 5
<210> 1512
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1512
Phe Leu Gly Thr His Trp Leu Met Gly Asn Ile Leu Arg
1 5 10
<210> 1513
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1513
Phe Leu Gly Val Thr Gln Phe Ser Pro Thr His Ala Arg
1 5 10
<210> 1514
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1514
Phe Leu His Gln Asp Ile Asp Ser Gly Gln Gly Ile Arg
1 5 10
<210> 1515
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1515
Phe Leu His Val Pro Asp Thr Phe Glu Gly His Phe Asp Gly Val Pro
1 5 10 15
Val Ile Ser Lys
20
<210> 1516
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1516
Phe Leu Ile Ala Thr Gly Glu Arg Pro Arg
1 5 10
<210> 1517
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1517
Phe Leu Ile Pro Asn Ala Ser Gln Ala Glu Ser Lys
1 5 10
<210> 1518
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1518
Phe Leu Ile Ser Arg
1 5
<210> 1519
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1519
Phe Leu Ile Val Gly Pro Gln Lys
1 5
<210> 1520
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1520
Phe Leu Leu Phe Gly Ile Gln Asp Gly Lys Arg
1 5 10
<210> 1521
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1521
Phe Leu Leu Lys Ala Glu Pro Leu Ala Phe Thr Phe Ser His Asp Tyr
1 5 10 15
Lys
<210> 1522
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1522
Phe Leu Leu Met Ser Gly Gly Lys Pro Ser Arg
1 5 10
<210> 1523
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1523
Phe Leu Leu Gln Ala Arg
1 5
<210> 1524
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1524
Phe Leu Leu Gln Ser Gly Leu Lys
1 5
<210> 1525
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1525
Phe Leu Leu Ser Arg
1 5
<210> 1526
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1526
Phe Leu Leu Tyr Gly Leu His Glu Gly Lys
1 5 10
<210> 1527
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1527
Phe Leu Leu Tyr Gly Leu His Glu Gly Lys Arg
1 5 10
<210> 1528
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1528
Phe Leu Leu Tyr Gly Leu Ser Gly Arg
1 5
<210> 1529
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1529
Phe Leu Asn Asp Val Lys
1 5
<210> 1530
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1530
Phe Leu Asn Val Leu Ser Pro Arg
1 5
<210> 1531
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1531
Phe Leu Asn Trp Ile Lys
1 5
<210> 1532
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1532
Phe Leu Pro Phe Lys
1 5
<210> 1533
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1533
Phe Leu Gln Asp Tyr Phe Asp Gly Asn Leu Lys
1 5 10
<210> 1534
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1534
Phe Leu Gln Glu Gln Gly His Arg
1 5
<210> 1535
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1535
Phe Leu Gln Ser Phe Ala Arg
1 5
<210> 1536
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1536
Phe Leu Val Ala Leu Ile Ser Arg
1 5
<210> 1537
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1537
Phe Leu Val Asn Leu Val Lys
1 5
<210> 1538
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1538
Phe Leu Val Ser Leu Ala Leu Arg
1 5
<210> 1539
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1539
Phe Leu Tyr His Lys
1 5
<210> 1540
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1540
Phe Met Glu Thr Val Ala Glu Lys
1 5
<210> 1541
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1541
Phe Met Gln Ala Val Thr Gly Trp Lys
1 5
<210> 1542
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1542
Phe Asn Ala Leu Gln Tyr Leu Arg
1 5
<210> 1543
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1543
Phe Asn Ala Val Leu Thr Asn Pro Gln Gly Asp Tyr Asp Thr Ser Thr
1 5 10 15
Gly Lys
<210> 1544
<211> 23
<212> PRT
<213> Homo sapiens
<400> 1544
Phe Asn Glu Glu His Ile Pro Asp Ser Pro Phe Val Val Pro Val Ala
1 5 10 15
Ser Pro Ser Gly Asp Ala Arg
20
<210> 1545
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1545
Phe Asn Glu Glu Val Lys Lys
1 5
<210> 1546
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1546
Phe Asn Gly Thr His Ile Pro Gly Ser Pro Phe Lys
1 5 10
<210> 1547
<211> 24
<212> PRT
<213> Homo sapiens
<400> 1547
Phe Asn His Leu Gly His Ile Phe Thr Phe Thr Pro Gln Asn Asn Glu
1 5 10 15
Phe Gln Leu Gln Leu Ser Pro Lys
20
<210> 1548
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1548
Phe Asn Lys Asn Asn Glu Gly Thr Tyr Tyr Ser Pro Asn Tyr Asn Pro
1 5 10 15
Gln Ser Arg
<210> 1549
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1549
Phe Asn Lys Pro Phe Val Phe Leu Met Ile Glu Gln Asn Thr Lys
1 5 10 15
<210> 1550
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1550
Phe Asn Lys Pro Phe Val Phe Leu Met Ile Glu Gln Asn Thr Lys Ser
1 5 10 15
Pro Leu Phe Met Gly Lys
20
<210> 1551
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1551
Phe Asn Leu Thr Glu Thr Ser Glu Ala Glu Ile His Gln Ser Phe Gln
1 5 10 15
His Leu Leu Arg
20
<210> 1552
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1552
Phe Asn Arg Pro Phe Leu Met Ile Ile Val Pro Thr Asp Thr Gln Asn
1 5 10 15
Ile Phe Phe Met Ser Lys
20
<210> 1553
<211> 27
<212> PRT
<213> Homo sapiens
<400> 1553
Phe Asn Arg Pro Phe Leu Met Ile Ile Val Pro Thr Asp Thr Gln Asn
1 5 10 15
Ile Phe Phe Met Ser Lys Val Thr Asn Pro Lys
20 25
<210> 1554
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1554
Phe Asn Thr Ala Asn Asp Asp Asn Val Thr Gln Val Arg
1 5 10
<210> 1555
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1555
Phe Asn Thr Phe Ile His Glu Asp Ile Trp Asn Ile Arg
1 5 10
<210> 1556
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1556
Phe Pro Ala Ile Gln Asn Leu Ala Leu Arg
1 5 10
<210> 1557
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1557
Phe Pro Cys Gly Arg Pro Trp Lys
1 5
<210> 1558
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1558
Phe Pro Glu Val Asp Val Leu Thr Lys
1 5
<210> 1559
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1559
Phe Pro Phe Leu Phe Asn Gly Lys
1 5
<210> 1560
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1560
Phe Pro His Leu Phe Thr Gly Lys
1 5
<210> 1561
<211> 27
<212> PRT
<213> Homo sapiens
<400> 1561
Phe Pro Leu Tyr Asn Leu Gly Phe Gly His Asn Val Asp Phe Asn Phe
1 5 10 15
Leu Glu Val Met Ser Met Glu Asn Asn Gly Arg
20 25
<210> 1562
<211> 29
<212> PRT
<213> Homo sapiens
<400> 1562
Phe Pro Leu Tyr Asn Leu Gly Phe Gly Asn Asn Leu Asn Tyr Asn Phe
1 5 10 15
Leu Glu Asn Met Ala Leu Glu Asn His Gly Phe Ala Arg
20 25
<210> 1563
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1563
Phe Pro Ser Gly Thr Phe Glu Gln Val Ser Gln Leu Val Lys
1 5 10
<210> 1564
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1564
Phe Pro Ser Ser Gln Asp His Pro Leu Pro Ser Ala Glu Arg
1 5 10
<210> 1565
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1565
Phe Pro Val Glu Met Thr His Asn His Asn Phe Arg
1 5 10
<210> 1566
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1566
Phe Pro Val Phe Met Gly Arg
1 5
<210> 1567
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1567
Phe Pro Val Ile Gln His Phe Lys
1 5
<210> 1568
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1568
Phe Gln Ala Ser Val Ala Thr Pro Arg
1 5
<210> 1569
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1569
Phe Gln Asp Leu Val Asp Ala Val Arg
1 5
<210> 1570
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1570
Phe Gln Asp Thr Asp Gly Lys
1 5
<210> 1571
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1571
Phe Gln Glu Glu Glu Lys
1 5
<210> 1572
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1572
Phe Gln Glu Gly Gln Glu Glu Glu Arg
1 5
<210> 1573
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1573
Phe Gln Phe Ile Lys
1 5
<210> 1574
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1574
Phe Gln Phe Pro Gly Lys Pro Gly Ile Tyr Thr Arg
1 5 10
<210> 1575
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1575
Phe Gln Gly Ala Gly Ser Asn Lys
1 5
<210> 1576
<211> 24
<212> PRT
<213> Homo sapiens
<400> 1576
Phe Gln Ile Leu Thr Leu Trp Leu Pro Asp Ser Leu Thr Thr Trp Glu
1 5 10 15
Ile His Gly Leu Ser Leu Ser Lys
20
<210> 1577
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1577
Phe Gln Asn Ala Leu Leu Val Arg
1 5
<210> 1578
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1578
Phe Gln Asn Ser Ala Ile Leu Thr Ile Gln Pro Lys
1 5 10
<210> 1579
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1579
Phe Gln Pro Thr Leu Leu Thr Leu Pro Arg
1 5 10
<210> 1580
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1580
Phe Gln Ser His Ile Ile Ile Arg
1 5
<210> 1581
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1581
Phe Gln Ser Val Phe Thr Val Thr Arg
1 5
<210> 1582
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1582
Phe Gln Val Asp Asn Asn Asn Arg
1 5
<210> 1583
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1583
Phe Arg Glu Thr Leu Glu Asp Thr Arg
1 5
<210> 1584
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1584
Phe Arg Ile Glu Asp Gly Phe Ser Leu Lys
1 5 10
<210> 1585
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1585
Phe Arg Leu Pro Glu Ile Ser Arg
1 5
<210> 1586
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1586
Phe Arg Pro Asp Gly Leu Pro Lys
1 5
<210> 1587
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1587
Phe Arg Pro Phe Gln Phe Gly Ser Ala Lys
1 5 10
<210> 1588
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1588
Phe Arg Pro Thr Leu Val Phe Arg
1 5
<210> 1589
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1589
Phe Ser Ala Glu Phe Asp Phe Arg
1 5
<210> 1590
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1590
Phe Ser Ala Ile Cys Gln Gly Asp Gly Thr Trp Ser Pro Arg
1 5 10
<210> 1591
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1591
Phe Ser Ala Ser Leu Ala Pro His Phe Asn Ser Leu Pro Arg
1 5 10
<210> 1592
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1592
Phe Ser Cys Phe Gln Glu Glu Ala Pro Gln Pro His Tyr Gln Leu Arg
1 5 10 15
<210> 1593
<211> 27
<212> PRT
<213> Homo sapiens
<400> 1593
Phe Ser Asp Glu Gly Thr His Glu Ser Gln Ile Ser Phe Thr Ile Glu
1 5 10 15
Gly Pro Leu Thr Ser Phe Gly Leu Ser Asn Lys
20 25
<210> 1594
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1594
Phe Ser Asp Gly Leu Glu Ser Asn Ser Ser Thr Gln Phe Glu Val Lys
1 5 10 15
<210> 1595
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1595
Phe Ser Glu His Ile Lys
1 5
<210> 1596
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1596
Phe Ser Glu Trp Gly Asn Asn Ala Phe Phe Tyr Tyr Phe Glu His Arg
1 5 10 15
<210> 1597
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1597
Phe Ser Gly Gln Leu Asn Ser His Gly Cys Phe Tyr Gln Gln Val Lys
1 5 10 15
<210> 1598
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1598
Phe Ser Gly Ser Lys
1 5
<210> 1599
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1599
Phe Ser Gly Thr Trp Tyr Ala Met Ala Lys
1 5 10
<210> 1600
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1600
Phe Ser Gly Trp Tyr Asp Ala Asp Leu Ser Pro Ala Gly His Glu Glu
1 5 10 15
Ala Lys
<210> 1601
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1601
Phe Ser His Glu Glu Ile Ala Met Ala Thr Val Thr Ala Leu Arg
1 5 10 15
<210> 1602
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1602
Phe Ser His Glu Glu Ile Ala Met Ala Thr Val Thr Ala Leu Arg Arg
1 5 10 15
<210> 1603
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1603
Phe Ser His Thr Lys
1 5
<210> 1604
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1604
Phe Ser His Thr Lys Ser Val Phe Leu His Ala Arg
1 5 10
<210> 1605
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1605
Phe Ser His Val Glu Lys
1 5
<210> 1606
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1606
Phe Ser Ile Glu Gly Ser Tyr Gln Leu Glu Lys
1 5 10
<210> 1607
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1607
Phe Ser Ile Ser Ala Thr Tyr Asp Leu Gly Ala Thr Leu Leu Lys
1 5 10 15
<210> 1608
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1608
Phe Ser Ile Ser Arg
1 5
<210> 1609
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1609
Phe Ser Leu Asp Gly Lys
1 5
<210> 1610
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1610
Phe Ser Leu Phe Thr Ala Val His Lys
1 5
<210> 1611
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1611
Phe Ser Leu Ser Arg
1 5
<210> 1612
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1612
Phe Ser Pro Ala Thr His Pro Ser Glu Gly Leu Glu Glu Asn Tyr Cys
1 5 10 15
Arg
<210> 1613
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1613
Phe Ser Pro Glu Asn Thr Arg
1 5
<210> 1614
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1614
Phe Ser Pro Glu Asn Thr Arg Lys
1 5
<210> 1615
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1615
Phe Ser Ser His Gly Cys Lys
1 5
<210> 1616
<211> 28
<212> PRT
<213> Homo sapiens
<400> 1616
Phe Ser Ser His Val Gly Gly Thr Leu Gly Gln Phe Tyr Gln Glu Val
1 5 10 15
Leu Trp Gly Ser Pro Ala Ala Ser Asp Asp Gly Arg
20 25
<210> 1617
<211> 29
<212> PRT
<213> Homo sapiens
<400> 1617
Phe Ser Ser His Val Gly Gly Thr Leu Gly Gln Phe Tyr Gln Glu Val
1 5 10 15
Leu Trp Gly Ser Pro Ala Ala Ser Asp Asp Gly Arg Arg
20 25
<210> 1618
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1618
Phe Ser Ser Leu Tyr Ile Ser Gln Phe Ile Ile Met Tyr Ser Leu Asp
1 5 10 15
Gly Lys Lys
<210> 1619
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1619
Phe Ser Ser Ser Ser Gly Tyr Gly Gly Gly Ser Ser Arg
1 5 10
<210> 1620
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1620
Phe Ser Thr Glu Tyr Glu Leu Gln Gln Leu Glu Gln Phe Lys
1 5 10
<210> 1621
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1621
Phe Ser Thr Glu Tyr Glu Leu Gln Gln Leu Glu Gln Phe Lys Lys
1 5 10 15
<210> 1622
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1622
Phe Ser Thr Phe Ala Gly Phe Leu Leu Phe Glu Thr Lys
1 5 10
<210> 1623
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1623
Phe Ser Thr Phe Leu Ser Leu Leu Glu Ala Ala Asp Leu Lys
1 5 10
<210> 1624
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1624
Phe Ser Thr Val Ala Gly Glu Ser Gly Ser Ala Asp Thr Val Arg Asp
1 5 10 15
Pro Arg
<210> 1625
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1625
Phe Ser Val Leu Leu Leu His Gly Ile Arg
1 5 10
<210> 1626
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1626
Phe Ser Val Ser Leu Lys
1 5
<210> 1627
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1627
Phe Ser Val Val Tyr Ala Lys
1 5
<210> 1628
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1628
Phe Ser Tyr Ser Ser Gly His Val His Leu Ser Ser Glu Asn Lys
1 5 10 15
<210> 1629
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1629
Phe Thr Ala Asp Gln Lys
1 5
<210> 1630
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1630
Phe Thr Asp His Leu Lys
1 5
<210> 1631
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1631
Phe Thr Glu Asp Ala Lys
1 5
<210> 1632
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1632
Phe Thr Glu Asp Ala Lys Arg
1 5
<210> 1633
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1633
Phe Thr Phe Glu Tyr Ser Arg
1 5
<210> 1634
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1634
Phe Thr Gly Ser Gln Pro Phe Gly Gln Gly Val Glu His Ala Thr Ala
1 5 10 15
Asn Lys
<210> 1635
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1635
Phe Thr Ile Ser Arg
1 5
<210> 1636
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1636
Phe Thr Lys Glu Thr Tyr Asp Phe Asp Ile Ala Val Leu Arg
1 5 10
<210> 1637
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1637
Phe Thr Leu Val Val Pro His Gln His Arg
1 5 10
<210> 1638
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1638
Phe Thr Asn Ile Gly Pro Asp Thr Met Arg
1 5 10
<210> 1639
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1639
Phe Thr Pro Glu Lys
1 5
<210> 1640
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1640
Phe Thr Pro Thr Glu Thr Asn Lys
1 5
<210> 1641
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1641
Phe Thr Pro Val Ala Ser Lys
1 5
<210> 1642
<211> 24
<212> PRT
<213> Homo sapiens
<400> 1642
Phe Thr Gln Val Thr Pro Thr Ser Leu Ser Ala Gln Trp Thr Pro Pro
1 5 10 15
Asn Val Gln Leu Thr Gly Tyr Arg
20
<210> 1643
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1643
Phe Thr Arg Pro Leu Phe Lys
1 5
<210> 1644
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1644
Phe Thr Val Asp Arg Pro Phe Leu Phe Leu Ile Tyr Glu His Arg
1 5 10 15
<210> 1645
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1645
Phe Thr Val Glu Thr Pro Asp Lys
1 5
<210> 1646
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1646
Phe Thr Val Ser Val Asn Val Ala Ala Gly Ser Lys
1 5 10
<210> 1647
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1647
Phe Thr Val Val Ala Ile Ser Pro Pro Arg Lys
1 5 10
<210> 1648
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1648
Phe Val Ala Ser Pro Leu Ala Lys
1 5
<210> 1649
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1649
Phe Val Cys Asn Ser Gly Tyr Lys
1 5
<210> 1650
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1650
Phe Val Phe Asp Arg Pro Leu Pro Val Ser Arg
1 5 10
<210> 1651
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1651
Phe Val Leu His Ala Val Gln Leu Val Lys
1 5 10
<210> 1652
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1652
Phe Val Leu Ser Ser Gly Lys
1 5
<210> 1653
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1653
Phe Val Gln Gly Lys
1 5
<210> 1654
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1654
Phe Val Ser Asp Tyr Glu Thr His Gly Ala Gly Phe Ser Ile Arg
1 5 10 15
<210> 1655
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1655
Phe Val Thr Gln Ala Glu Gly Ala Lys
1 5
<210> 1656
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1656
Phe Val Thr Gln Lys
1 5
<210> 1657
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1657
Phe Val Thr Val Gln Ala Thr Phe Gly Thr Gln Val Val Glu Lys
1 5 10 15
<210> 1658
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1658
Phe Val Thr Trp Ile Glu Gly Val Met Arg
1 5 10
<210> 1659
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1659
Phe Val Tyr His Leu Ser Asp Leu Cys Lys
1 5 10
<210> 1660
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1660
Phe Val Tyr His Leu Ser Asp Leu Cys Lys Lys
1 5 10
<210> 1661
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1661
Phe Val Tyr Pro Val Pro Tyr Thr Thr Arg Pro Pro Arg
1 5 10
<210> 1662
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1662
Phe Trp Asp Tyr Leu Arg
1 5
<210> 1663
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1663
Phe Trp Thr Ser Phe Phe Pro Lys
1 5
<210> 1664
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1664
Phe Tyr Ala Leu Ser Ala Ser Phe Glu Pro Phe Ser Asn Lys
1 5 10
<210> 1665
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1665
Phe Tyr Glu Glu Val His Asp Leu Glu Arg
1 5 10
<210> 1666
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1666
Phe Tyr Gly Asp Glu Glu Lys
1 5
<210> 1667
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1667
Phe Tyr Gly Asp Glu Glu Lys Asp Lys
1 5
<210> 1668
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1668
Phe Tyr Gly Asn Arg
1 5
<210> 1669
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1669
Phe Tyr Ile Ser Lys
1 5
<210> 1670
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1670
Phe Tyr Leu Ser Lys
1 5
<210> 1671
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1671
Phe Tyr Asn Gln Val Ser Thr Pro Leu Leu Arg
1 5 10
<210> 1672
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1672
Phe Tyr Ser Glu Lys
1 5
<210> 1673
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1673
Phe Tyr Thr Phe Leu Lys
1 5
<210> 1674
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1674
Phe Tyr Tyr Ile Tyr Asn Glu Lys
1 5
<210> 1675
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1675
Phe Tyr Tyr Ile Tyr Asn Glu Lys Gly Leu Glu Val Thr Ile Thr Ala
1 5 10 15
Arg
<210> 1676
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1676
Phe Tyr Tyr Leu Ile Ala Ser Glu Thr Pro Gly Lys
1 5 10
<210> 1677
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1677
Gly Ala Ala Val Ser Asn Asn Ile Val Val Arg Pro Ser Arg
1 5 10
<210> 1678
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1678
Gly Ala Asp Leu Ser Leu Arg
1 5
<210> 1679
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1679
Gly Ala Asp Val Trp Phe Lys
1 5
<210> 1680
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1680
Gly Ala Asp Tyr Ser Leu Arg
1 5
<210> 1681
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1681
Gly Ala Glu Phe Leu Leu Arg
1 5
<210> 1682
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1682
Gly Ala Phe Gln Gln Ala Ala Gln Ile Leu Leu His Ala Arg
1 5 10
<210> 1683
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1683
Gly Ala Gly Ala Phe Gly Tyr Phe Glu Val Thr His Asp Ile Thr Lys
1 5 10 15
<210> 1684
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1684
Gly Ala Gly His Met Val Pro Thr Asp Lys Pro Leu Ala Ala Phe Thr
1 5 10 15
Met Phe Ser Arg
20
<210> 1685
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1685
Gly Ala Gly Thr Gly Gly Leu Gly Leu Ala Val Glu Gly Pro Ser Glu
1 5 10 15
Ala Lys
<210> 1686
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1686
Gly Ala His Val Thr Ile Asn Ala Arg
1 5
<210> 1687
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1687
Gly Ala Leu Ala Leu Glu Glu Lys
1 5
<210> 1688
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1688
Gly Ala Leu His Asn Tyr Lys
1 5
<210> 1689
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1689
Gly Ala Leu Gln Asn Ile Ile Pro Ala Ser Thr Gly Ala Ala Lys
1 5 10 15
<210> 1690
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1690
Gly Ala Pro Leu Ala Lys
1 5
<210> 1691
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1691
Gly Ala Ser Ala Tyr Phe Leu Phe Leu Arg
1 5 10
<210> 1692
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1692
Gly Ala Ser Gln Ala Gly Ala Pro Gln Gly Arg
1 5 10
<210> 1693
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1693
Gly Ala Thr Asp Asn Lys Gly Pro Val Leu Ala Trp Ile Asn Ala Val
1 5 10 15
Ser Ala Phe Arg
20
<210> 1694
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1694
Gly Ala Thr Thr Ser Pro Gly Val Tyr Glu Leu Ser Ser Arg
1 5 10
<210> 1695
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1695
Gly Ala Thr Tyr Asn Ile Ile Val Glu Ala Leu Lys
1 5 10
<210> 1696
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1696
Gly Ala Thr Tyr Asn Ile Ile Val Glu Ala Leu Lys Asp Gln Gln Arg
1 5 10 15
<210> 1697
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1697
Gly Ala Val His Val Val Val Ala Glu Thr Asp Tyr Gln Ser Phe Ala
1 5 10 15
Val Leu Tyr Leu Glu Arg
20
<210> 1698
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1698
Gly Ala Val Tyr Val Tyr Phe Gly Ser Lys
1 5 10
<210> 1699
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1699
Gly Ala Tyr Pro Leu Ser Ile Glu Pro Ile Gly Val Arg
1 5 10
<210> 1700
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1700
Gly Ala Tyr Gln Asn Asn Glu Ile Lys
1 5
<210> 1701
<211> 24
<212> PRT
<213> Homo sapiens
<400> 1701
Gly Ala Tyr Gln Asn Asn Glu Ile Lys His Ile Tyr Ala Ile Ser Ser
1 5 10 15
Ala Ala Leu Ser Ala Ser Tyr Lys
20
<210> 1702
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1702
Gly Asp Ala Cys Glu Gly Asp Ser Gly Gly Pro Phe Val Met Lys
1 5 10 15
<210> 1703
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1703
Gly Asp Ala Thr Val Phe Phe Ile Leu Pro Asn Gln Gly Lys
1 5 10
<210> 1704
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1704
Gly Asp Ala Val Cys Thr Glu Ser Gly Trp Arg Pro Leu Pro Ser Cys
1 5 10 15
Glu Glu Lys
<210> 1705
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1705
Gly Asp Asp Ile Thr Met Val Leu Ile Leu Pro Lys Pro Glu Lys
1 5 10 15
<210> 1706
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1706
Gly Asp Asp Thr Pro Leu His Leu Ala Ala Ser His Gly His Arg
1 5 10 15
<210> 1707
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1707
Gly Asp Glu Leu Ala Asp Ser Ala Leu Glu Ile Phe Lys
1 5 10
<210> 1708
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1708
Gly Asp Phe Ser Ser Ala Asn Asn Arg
1 5
<210> 1709
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1709
Gly Asp Phe Ser Ser Ala Asn Asn Arg Asp Asn Thr Tyr Asn Arg
1 5 10 15
<210> 1710
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1710
Gly Asp Gly Pro Val Gln Gly Ile Ile Asn Phe Glu Gln Lys
1 5 10
<210> 1711
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1711
Gly Asp Gly Thr Phe Val Asp Ala Ala Ala Ser Ala Gly Val Asp Asp
1 5 10 15
Pro His Gln His Gly Arg
20
<210> 1712
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1712
Gly Asp Ile Leu Gln Arg
1 5
<210> 1713
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1713
Gly Asp Lys Val Trp Val Tyr Pro Pro Glu Lys
1 5 10
<210> 1714
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1714
Gly Asp Leu Gly Ile Glu Ile Pro Ala Glu Lys
1 5 10
<210> 1715
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1715
Gly Asp Leu Tyr Phe Ala Asn Val Glu Glu Lys
1 5 10
<210> 1716
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1716
Gly Asp Met Phe Leu Val Ala Asn Leu Gly Thr Lys
1 5 10
<210> 1717
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1717
Gly Asp Ser Phe Thr His Thr Pro Pro Leu Asp Pro Gln Glu Leu Asp
1 5 10 15
Ile Leu Lys
<210> 1718
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1718
Gly Asp Ser Gly Gly Ala Phe Ala Val Gln Asp Pro Asn Asp Lys
1 5 10 15
<210> 1719
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1719
Gly Asp Ser Gly Gly Pro Leu Ile Val His Lys
1 5 10
<210> 1720
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1720
Gly Asp Ser Gly Gly Pro Leu Ile Val His Lys Arg
1 5 10
<210> 1721
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1721
Gly Asp Ser Pro Ala Ser Ser Lys Pro Ile Ser Ile Asn Tyr Arg
1 5 10 15
<210> 1722
<211> 37
<212> PRT
<213> Homo sapiens
<400> 1722
Gly Asp Ser Pro Ala Ser Ser Lys Pro Ile Ser Ile Asn Tyr Arg Thr
1 5 10 15
Glu Ile Asp Lys Pro Ser Gln Met Gln Val Thr Asp Val Gln Asp Asn
20 25 30
Ser Ile Ser Val Lys
35
<210> 1723
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1723
Gly Asp Ser Gln Ser Ser Trp Lys
1 5
<210> 1724
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1724
Gly Asp Ser Thr Phe Glu Ser Lys
1 5
<210> 1725
<211> 30
<212> PRT
<213> Homo sapiens
<400> 1725
Gly Asp Ser Val Val Trp Tyr Leu Phe Ser Ala Gly Asn Glu Ala Asp
1 5 10 15
Val His Gly Ile Tyr Phe Ser Gly Asn Thr Tyr Leu Trp Arg
20 25 30
<210> 1726
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1726
Gly Asp Val Ala Phe Val Lys
1 5
<210> 1727
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1727
Gly Asp Val Ala Phe Val Lys His Gln Thr Val Pro Gln Asn Thr Gly
1 5 10 15
Gly Lys
<210> 1728
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1728
Gly Asp Tyr Asp Ala Phe Phe Glu Ala Arg
1 5 10
<210> 1729
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1729
Gly Asp Tyr Pro Leu Glu Ala Val Arg
1 5
<210> 1730
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1730
Gly Asp Tyr Thr Leu Asn Asn Val His Ala Cys Ala Lys
1 5 10
<210> 1731
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1731
Gly Glu Ala Phe Thr Leu Lys
1 5
<210> 1732
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1732
Gly Glu Ala Phe Thr Leu Lys Ala Thr Val Leu Asn Tyr Leu Pro Lys
1 5 10 15
<210> 1733
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1733
Gly Glu Phe Val Trp Lys
1 5
<210> 1734
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1734
Gly Glu Phe Tyr Ile Gly Ser Lys
1 5
<210> 1735
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1735
Gly Glu Ile Phe Phe Phe Lys
1 5
<210> 1736
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1736
Gly Glu Ile His Leu Gly Arg
1 5
<210> 1737
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1737
Gly Glu Ile Gln Asn Ile Leu Gln Lys
1 5
<210> 1738
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1738
Gly Glu Leu Phe Phe Phe Lys
1 5
<210> 1739
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1739
Gly Glu Leu Leu Glu Ala Ile Lys
1 5
<210> 1740
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1740
Gly Glu Leu Leu Glu Ala Ile Lys Arg
1 5
<210> 1741
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1741
Gly Glu Leu Ser Ala Arg Met Lys
1 5
<210> 1742
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1742
Gly Glu Met Met Asp Leu Gln His Gly Ser Leu Phe Leu Gln Thr Pro
1 5 10 15
Lys
<210> 1743
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1743
Gly Glu Asn Ala Leu Lys Asp Ala Lys
1 5
<210> 1744
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1744
Gly Glu Asn Leu Phe Ala Ile Thr Asp Glu Gly Met Asp Val Pro Leu
1 5 10 15
Ala Met Glu Glu Trp His His Glu Arg
20 25
<210> 1745
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1745
Gly Glu Pro Phe Ile Arg
1 5
<210> 1746
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1746
Gly Glu Pro Gly Asp Pro Val Asn Leu Leu Arg
1 5 10
<210> 1747
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1747
Gly Glu Pro Ser Leu Pro Glu Lys
1 5
<210> 1748
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1748
Gly Glu Pro Thr Asp Arg Tyr Val Gly Phe Cys Met Lys
1 5 10
<210> 1749
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1749
Gly Glu Gln Ile Gln Leu Lys
1 5
<210> 1750
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1750
Gly Glu Ser Gly Gly Ala Val Phe Leu Glu Arg
1 5 10
<210> 1751
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1751
Gly Glu Ser Gly Tyr Val Ala Ser Glu Gly Phe Pro Asn Leu Tyr Pro
1 5 10 15
Pro Asn Lys
<210> 1752
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1752
Gly Glu Ser Lys Leu Glu Val Leu Asn Phe Asp Phe Gln Ala Asn Ala
1 5 10 15
Gln Leu Ser Asn Pro Lys
20
<210> 1753
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1753
Gly Glu Ser Pro Val Asp Tyr Asp Gly Gly Arg
1 5 10
<210> 1754
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1754
Gly Glu Thr His Glu Gln Val His Ser Ile Leu His Phe Lys
1 5 10
<210> 1755
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1755
Gly Glu Val Phe Thr Leu Lys
1 5
<210> 1756
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1756
Gly Glu Val Leu Asp Asn Ser Phe Thr Gly Gly Ile Cys Lys
1 5 10
<210> 1757
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1757
Gly Glu Val Leu Pro Leu Pro Glu Ala Asn Phe Pro Ser Phe Pro Leu
1 5 10 15
Pro His His Lys
20
<210> 1758
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1758
Gly Glu Val Pro Pro Arg
1 5
<210> 1759
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1759
Gly Glu Val Pro Pro Arg Tyr Pro Arg
1 5
<210> 1760
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1760
Gly Glu Val Gln Ala Met Leu Gly Gln Ser Thr Glu Glu Leu Arg
1 5 10 15
<210> 1761
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1761
Gly Glu Trp Pro Trp Gln Val Thr Leu His Thr Thr Ser Pro Thr Gln
1 5 10 15
Arg
<210> 1762
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1762
Gly Glu Trp Thr Cys Ile Ala Tyr Ser Gln Leu Arg
1 5 10
<210> 1763
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1763
Gly Glu Trp Thr Cys Lys Pro Ile Ala Glu Lys
1 5 10
<210> 1764
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1764
Gly Glu Trp Val Ala Leu Asn Pro Leu Arg
1 5 10
<210> 1765
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1765
Gly Glu Trp Val Ala Leu Asn Pro Leu Arg Lys
1 5 10
<210> 1766
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1766
Gly Glu Tyr Glu Glu His Leu Gly Ile Leu Gly Pro Ile Ile Arg
1 5 10 15
<210> 1767
<211> 32
<212> PRT
<213> Homo sapiens
<400> 1767
Gly Glu Tyr Phe Ala Phe Leu Glu Thr Tyr Gly Thr His Tyr Ser Ser
1 5 10 15
Ser Gly Ser Leu Gly Gly Leu Tyr Glu Leu Ile Tyr Val Leu Asp Lys
20 25 30
<210> 1768
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1768
Gly Glu Tyr Phe Trp Glu Lys
1 5
<210> 1769
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1769
Gly Phe Glu Pro Thr Leu Glu Ala Leu Phe Gly Lys
1 5 10
<210> 1770
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1770
Gly Phe Phe Ala Asp Tyr Glu Ile Pro Asn Leu Gln Lys
1 5 10
<210> 1771
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1771
Gly Phe Gly Gly Leu Thr Gly Gln Ile Val Ala Ala Leu Ser Thr Ala
1 5 10 15
Lys
<210> 1772
<211> 26
<212> PRT
<213> Homo sapiens
<400> 1772
Gly Phe Gly Gly Val Gln Val Ser Pro Pro Asn Glu Asn Val Ala Ile
1 5 10 15
His Asn Pro Phe Arg Pro Trp Trp Glu Arg
20 25
<210> 1773
<211> 26
<212> PRT
<213> Homo sapiens
<400> 1773
Gly Phe Gly Ser Leu Asn Asp Glu Gly Glu Gly Glu Phe Trp Leu Gly
1 5 10 15
Asn Asp Tyr Leu His Leu Leu Thr Gln Arg
20 25
<210> 1774
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1774
Gly Phe Gly Tyr Lys
1 5
<210> 1775
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1775
Gly Phe Gly Tyr Val Val Ala Phe Arg Pro Tyr Gly Lys
1 5 10
<210> 1776
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1776
Gly Phe Ile Tyr Lys Pro Asp Leu Lys
1 5
<210> 1777
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1777
Gly Phe Leu Leu Leu Ala Ser Leu Arg
1 5
<210> 1778
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1778
Gly Phe Leu Leu Trp Tyr Ser Gly Arg
1 5
<210> 1779
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1779
Gly Phe Met Gln Thr Tyr Tyr Asp Asp His Leu Arg
1 5 10
<210> 1780
<211> 26
<212> PRT
<213> Homo sapiens
<400> 1780
Gly Phe Pro Ile Lys Glu Asp Phe Leu Glu Gln Ser Glu Gln Leu Phe
1 5 10 15
Gly Ala Lys Pro Val Ser Leu Thr Gly Lys
20 25
<210> 1781
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1781
Gly Phe Pro Thr Ile Tyr Phe Ser Pro Ala Asn Lys
1 5 10
<210> 1782
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1782
Gly Phe Pro Thr Ile Tyr Phe Ser Pro Ala Asn Lys Lys
1 5 10
<210> 1783
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1783
Gly Phe Gln His Leu Leu His Thr Leu Asn Leu Pro Gly His Gly Leu
1 5 10 15
Glu Thr Arg
<210> 1784
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1784
Gly Phe Gln Gln Leu Leu Gln Glu Leu Asn Gln Pro Arg
1 5 10
<210> 1785
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1785
Gly Phe Gln Val Ala Pro Glu His His Asn Asp His Lys
1 5 10
<210> 1786
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1786
Gly Phe Gln Val Val Val Thr Leu Arg
1 5
<210> 1787
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1787
Gly Phe Ser Leu Asp Glu Ala Thr Asn Leu Asn Gly Gly Leu Leu Arg
1 5 10 15
<210> 1788
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1788
Gly Phe Ser Ser Gly Ser Ala Val Val Ser Gly Gly Ser Arg
1 5 10
<210> 1789
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1789
Gly Phe Thr Ile Pro Glu Ala Phe Arg
1 5
<210> 1790
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1790
Gly Phe Thr Thr Lys
1 5
<210> 1791
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1791
Gly Phe Val Leu Arg
1 5
<210> 1792
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1792
Gly Phe Val Val Ala Gly Pro Ser Arg
1 5
<210> 1793
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1793
Gly Phe Tyr Phe Asn Lys Pro Thr Gly Tyr Gly Ser Ser Ser Arg
1 5 10 15
<210> 1794
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1794
Gly Gly Ala Leu Asp Ile Lys
1 5
<210> 1795
<211> 36
<212> PRT
<213> Homo sapiens
<400> 1795
Gly Gly Ala Ser Glu His Ile Thr Thr Leu Ala Tyr Gln Glu Leu Pro
1 5 10 15
Thr Ala Asp Leu Met Gln Glu Trp Gly Asp Ala Val Gln Tyr Asn Pro
20 25 30
Ala Ile Ile Lys
35
<210> 1796
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1796
Gly Gly Glu Gly Thr Gly Tyr Phe Val Asp Phe Ser Val Arg
1 5 10
<210> 1797
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1797
Gly Gly Glu Thr Ala Gln Ser Ala Asp Pro Gln Trp Glu Gln Leu Asn
1 5 10 15
Asn Lys
<210> 1798
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1798
Gly Gly Glu Thr Ser Glu Met Tyr Leu Ile Gln Pro Asp Ser Ser Val
1 5 10 15
Lys Pro Tyr Arg
20
<210> 1799
<211> 38
<212> PRT
<213> Homo sapiens
<400> 1799
Gly Gly Glu Thr Ser Glu Met Tyr Leu Ile Gln Pro Asp Ser Ser Val
1 5 10 15
Lys Pro Tyr Arg Val Tyr Cys Asp Met Asn Thr Glu Asn Gly Gly Trp
20 25 30
Thr Val Ile Gln Asn Arg
35
<210> 1800
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1800
Gly Gly Phe Val Leu Leu Asp Gly Glu Thr Phe Glu Val Lys
1 5 10
<210> 1801
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1801
Gly Gly Gly Ala Gly Phe Ile Ser Gly Leu Ser Tyr Leu Glu Leu Asp
1 5 10 15
Asn Pro Ala Gly Asn Lys
20
<210> 1802
<211> 23
<212> PRT
<213> Homo sapiens
<400> 1802
Gly Gly Gly Ala Gly Phe Ile Ser Gly Leu Ser Tyr Leu Glu Leu Asp
1 5 10 15
Asn Pro Ala Gly Asn Lys Arg
20
<210> 1803
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1803
Gly Gly Gly Ala Leu Leu Gly Asp Arg
1 5
<210> 1804
<211> 31
<212> PRT
<213> Homo sapiens
<400> 1804
Gly Gly Gly Gly Gly Gly Tyr Gly Ser Gly Gly Ser Ser Tyr Gly Ser
1 5 10 15
Gly Gly Gly Ser Tyr Gly Ser Gly Gly Gly Gly Gly Gly Gly Arg
20 25 30
<210> 1805
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1805
Gly Gly His Ser Ser Ser Leu Phe Gly Asn Ile Lys
1 5 10
<210> 1806
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1806
Gly Gly Ile Ser Gly Tyr Thr Leu Arg
1 5
<210> 1807
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1807
Gly Gly Lys Ile Glu Val Gln Leu Lys
1 5
<210> 1808
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1808
Gly Gly Asn Gln Leu Tyr Cys Val Lys
1 5
<210> 1809
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1809
Gly Gly Pro Phe Ser Asp Ser Tyr Arg
1 5
<210> 1810
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1810
Gly Gly Pro Leu Asp Gly Thr Tyr Arg
1 5
<210> 1811
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1811
Gly Gly Gln Ile Met Thr Leu Lys
1 5
<210> 1812
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1812
Gly Gly Ser Ala Ser Thr Trp Leu Thr Ala Phe Ala Leu Arg
1 5 10
<210> 1813
<211> 23
<212> PRT
<213> Homo sapiens
<400> 1813
Gly Gly Ser Gly Gly Ser Tyr Gly Gly Gly Gly Ser Gly Gly Gly Tyr
1 5 10 15
Gly Gly Gly Ser Gly Ser Arg
20
<210> 1814
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1814
Gly Gly Ser Ile Gln Gln Tyr Ile Tyr Lys
1 5 10
<210> 1815
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1815
Gly Gly Ser Ile Ser Gly Gly Gly Tyr Gly Ser Gly Gly Gly Lys
1 5 10 15
<210> 1816
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1816
Gly Gly Ser Thr Ser Tyr Gly Thr Gly Ser Glu Thr Glu Ser Pro Arg
1 5 10 15
<210> 1817
<211> 37
<212> PRT
<213> Homo sapiens
<400> 1817
Gly Gly Ser Thr Ser Tyr Gly Thr Gly Ser Glu Thr Glu Ser Pro Arg
1 5 10 15
Asn Pro Ser Ser Ala Gly Ser Trp Asn Ser Gly Ser Ser Gly Pro Gly
20 25 30
Ser Thr Gly Asn Arg
35
<210> 1818
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1818
Gly Gly Val Ala Ser Gly Phe Lys
1 5
<210> 1819
<211> 30
<212> PRT
<213> Homo sapiens
<400> 1819
Gly Gly Val Glu Asp Glu Val Thr Leu Ser Ala Tyr Ile Thr Ile Ala
1 5 10 15
Leu Leu Glu Ile Pro Leu Thr Val Thr His Pro Val Val Arg
20 25 30
<210> 1820
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1820
Gly Gly Val Val Gly Ile Lys Val Asp Lys
1 5 10
<210> 1821
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1821
Gly Gly Tyr Thr Leu Val Ser Gly Tyr Pro Lys
1 5 10
<210> 1822
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1822
Gly Gly Tyr Thr Leu Val Ser Gly Tyr Pro Lys Arg
1 5 10
<210> 1823
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1823
Gly His Ala Tyr Ser Val Thr Gly Ala Lys
1 5 10
<210> 1824
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1824
Gly His Phe Ser Ile Ser Ile Pro Val Lys
1 5 10
<210> 1825
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1825
Gly His Phe Ser Ile Ser Ile Pro Val Lys Ser Asp Ile Ala Pro Val
1 5 10 15
Ala Arg
<210> 1826
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1826
Gly His Gly Ala Thr Asn Asp Leu Thr Phe Thr Glu Glu Val Asp Met
1 5 10 15
Lys
<210> 1827
<211> 21
<212> PRT
<213> Homo sapiens
<400> 1827
Gly His Gly Ala Thr Asn Asp Leu Thr Phe Thr Glu Glu Val Asp Met
1 5 10 15
Lys Glu Met Glu Lys
20
<210> 1828
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1828
Gly His Gly Leu Gly His Gly His Glu Gln Gln His Gly Leu Gly His
1 5 10 15
Gly His Lys
<210> 1829
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1829
Gly His Gly Leu Thr Ala Leu Pro Ala Leu Pro Ala Arg
1 5 10
<210> 1830
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1830
Gly His Ile Leu Asp His Leu Asn Leu Lys
1 5 10
<210> 1831
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1831
Gly His Ile Tyr Gln Gly Ser Glu Ala Asp Ser Val Phe Ser Gly Phe
1 5 10 15
Leu Ile Phe Pro Ser Ala
20
<210> 1832
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1832
Gly His Leu Phe Leu Gln Thr Asp Gln Pro Ile Tyr Asn Pro Gly Gln
1 5 10 15
Arg
<210> 1833
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1833
Gly His Met Leu Glu Asn His Val Glu Arg
1 5 10
<210> 1834
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1834
Gly His Thr Pro Thr Gln Pro Gly Ala Leu Asn Gln Arg
1 5 10
<210> 1835
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1835
Gly His Val Ser Phe Lys Pro Ser Leu Asp Gln Gln Arg
1 5 10
<210> 1836
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1836
Gly His Tyr Phe Trp Met Leu Ser Pro Phe Ser Pro Pro Ser Pro Ala
1 5 10 15
Arg
<210> 1837
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1837
Gly His Tyr Thr Glu Gly Ala Glu Leu Ile Glu Asn Val Leu Glu Val
1 5 10 15
Val Arg
<210> 1838
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1838
Gly His Tyr Thr Ile Gly Lys
1 5
<210> 1839
<211> 37
<212> PRT
<213> Homo sapiens
<400> 1839
Gly Ile Glu Ile Leu Asn Gln Val Gln Glu Ser Leu Pro Glu Leu Ser
1 5 10 15
Asn His Ala Ser Ile Leu Ile Met Leu Thr Asp Gly Asp Pro Thr Glu
20 25 30
Gly Val Thr Asp Arg
35
<210> 1840
<211> 48
<212> PRT
<213> Homo sapiens
<400> 1840
Gly Ile Gly Glu Trp His Cys Gln Pro Leu Gln Thr Tyr Pro Ser Ser
1 5 10 15
Ser Gly Pro Val Glu Val Phe Ile Thr Glu Thr Pro Ser Gln Pro Asn
20 25 30
Ser His Pro Ile Gln Trp Asn Ala Pro Gln Pro Ser His Ile Ser Lys
35 40 45
<210> 1841
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1841
Gly Ile Ile Ala Leu Arg
1 5
<210> 1842
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1842
Gly Ile Ile Ser Ala Leu Leu Val Pro Pro Glu Thr Glu Glu Ala Lys
1 5 10 15
<210> 1843
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1843
Gly Ile Leu Ala Ala Asp Glu Ser Thr Gly Ser Ile Ala Lys
1 5 10
<210> 1844
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1844
Gly Ile Leu Ala Leu Arg
1 5
<210> 1845
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1845
Gly Ile Leu Gly Asn Ala Ile Lys
1 5
<210> 1846
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1846
Gly Ile Leu Asn Glu Ile Lys
1 5
<210> 1847
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1847
Gly Ile Leu Asn Glu Ile Lys Asp Arg
1 5
<210> 1848
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1848
Gly Ile Leu Ser Gly Thr Ser Asp Leu Leu Leu Thr Phe Asp Glu Ala
1 5 10 15
Glu Val Arg Lys
20
<210> 1849
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1849
Gly Ile Leu Thr Leu Lys
1 5
<210> 1850
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1850
Gly Ile Leu Val Gly Glu Ser Arg
1 5
<210> 1851
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1851
Gly Ile Pro Ile Lys
1 5
<210> 1852
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1852
Gly Ile Pro Ile Lys Lys
1 5
<210> 1853
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1853
Gly Ile Pro Leu Lys
1 5
<210> 1854
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1854
Gly Ile Gln Asn Asp Leu Thr Lys
1 5
<210> 1855
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1855
Gly Ile Gln Ser Leu Leu Asn Gly Gly Arg
1 5 10
<210> 1856
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1856
Gly Ile Gln Val Glu Ile Tyr Ser Phe Pro Lys
1 5 10
<210> 1857
<211> 37
<212> PRT
<213> Homo sapiens
<400> 1857
Gly Ile Ser Glu Gln Ser Leu Val Val Ser Gly Val Gln His Gln Ser
1 5 10 15
Thr Leu Glu Leu Ser Glu Val Gly Val Glu Ala Ala Ala Ala Thr Ser
20 25 30
Ile Ala Met Ser Arg
35
<210> 1858
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1858
Gly Ile Ser Met Leu Asn Lys
1 5
<210> 1859
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1859
Gly Ile Ser Gln Glu Gln Met Asn Glu Phe Arg
1 5 10
<210> 1860
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1860
Gly Ile Thr Gly Val Glu Asp Lys
1 5
<210> 1861
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1861
Gly Ile Thr Met Ala Thr Ala Lys
1 5
<210> 1862
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1862
Gly Ile Thr Tyr Tyr Lys
1 5
<210> 1863
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1863
Gly Ile Val Ala Ala Phe Tyr Ser Gly Pro Ser Leu Ser Asp Lys
1 5 10 15
<210> 1864
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1864
Gly Ile Val Ala Ala Phe Tyr Ser Gly Pro Ser Leu Ser Asp Lys Glu
1 5 10 15
Lys
<210> 1865
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1865
Gly Ile Val Asp Gln Ser Gln Gln Ala Tyr Gln Glu Ala Phe Glu Ile
1 5 10 15
Ser Lys
<210> 1866
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1866
Gly Ile Tyr Gly Thr Ile Ser Arg
1 5
<210> 1867
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1867
Gly Ile Tyr Ser Phe Asn Phe His Val Val Lys
1 5 10
<210> 1868
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1868
Gly Ile Tyr Ser Phe Ser Phe His Val Ile Lys
1 5 10
<210> 1869
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1869
Gly Lys Glu Glu Ser Leu Asp Ser Asp Leu Tyr Ala Glu Leu Arg
1 5 10 15
<210> 1870
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1870
Gly Lys Glu Gly Trp Ile His Thr Val Cys Ile Asn Gly Arg
1 5 10
<210> 1871
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1871
Gly Lys Ile Glu Glu Asp Ser Glu Val Leu Met Met Ile Lys
1 5 10
<210> 1872
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1872
Gly Lys Ile Thr Asp Leu Ile Lys
1 5
<210> 1873
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1873
Gly Lys Ile Val Asp Leu Leu Lys
1 5
<210> 1874
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1874
Gly Lys Leu Leu Ile Gly Thr Val Phe His Lys
1 5 10
<210> 1875
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1875
Gly Lys Met Asn Thr Val Ile Ala Ala Leu Ser Arg
1 5 10
<210> 1876
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1876
Gly Lys Thr Glu Gln Gln Thr Ala Asp Gln Leu Leu Ala Arg
1 5 10
<210> 1877
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1877
Gly Lys Val Val Gly Leu Ile Gln Asp Leu Lys Pro Asn Thr Ile Met
1 5 10 15
Val Leu Val Asn Tyr Ile His Phe Lys
20 25
<210> 1878
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1878
Gly Lys Trp Glu Arg Pro Phe Glu Val Lys
1 5 10
<210> 1879
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1879
Gly Lys Tyr Glu Met Tyr Leu Lys
1 5
<210> 1880
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1880
Gly Leu Ala Gly Ala Val Ser Glu Leu Leu Arg
1 5 10
<210> 1881
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1881
Gly Leu Ala Ser Ala Asn Val Asp Phe Ala Phe Ser Leu Tyr Lys
1 5 10 15
<210> 1882
<211> 23
<212> PRT
<213> Homo sapiens
<400> 1882
Gly Leu Ala Ser Ala Asn Val Asp Phe Ala Phe Ser Leu Tyr Lys His
1 5 10 15
Leu Val Ala Leu Ser Pro Lys
20
<210> 1883
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1883
Gly Leu Cys Val Ala Thr Pro Val Gln Leu Arg
1 5 10
<210> 1884
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1884
Gly Leu Glu Glu Glu Leu Gln Phe Ser Leu Gly Ser Lys
1 5 10
<210> 1885
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1885
Gly Leu Glu Ser Gln Thr Lys
1 5
<210> 1886
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1886
Gly Leu Glu Thr Ser Leu Ala Glu Cys Thr Phe Thr Lys
1 5 10
<210> 1887
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1887
Gly Leu Glu Val Thr Ile Thr Ala Arg
1 5
<210> 1888
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1888
Gly Leu Glu Trp Val Gly Arg
1 5
<210> 1889
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1889
Gly Leu Phe Ile Ile Asp Gly Lys
1 5
<210> 1890
<211> 24
<212> PRT
<213> Homo sapiens
<400> 1890
Gly Leu Phe Gln Val Val Ser Gly Gly Met Val Leu Gln Leu Gln Gln
1 5 10 15
Gly Asp Gln Val Trp Val Glu Lys
20
<210> 1891
<211> 27
<212> PRT
<213> Homo sapiens
<400> 1891
Gly Leu Phe Gln Val Val Ser Gly Gly Met Val Leu Gln Leu Gln Gln
1 5 10 15
Gly Asp Gln Val Trp Val Glu Lys Asp Pro Lys
20 25
<210> 1892
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1892
Gly Leu Gly Glu Ile Ser Ala Ala Ser Glu Phe Lys
1 5 10
<210> 1893
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1893
Gly Leu Gly Glu Leu Gln Glu Leu Tyr Leu Lys
1 5 10
<210> 1894
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1894
Gly Leu His Leu Gln Ala Leu Lys Pro Thr Lys Pro Gly Leu Leu Pro
1 5 10 15
Ser Leu Phe Lys
20
<210> 1895
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1895
Gly Leu Ile Asp Glu Val Asn Gln Asp Phe Thr Asn Arg
1 5 10
<210> 1896
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1896
Gly Leu Ile Asp Glu Val Asn Gln Asp Phe Thr Asn Arg Ile Asn Lys
1 5 10 15
<210> 1897
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1897
Gly Leu Lys Pro Gly Val Val Tyr Glu Gly Gln Leu Ile Ser Ile Gln
1 5 10 15
Gln Tyr Gly His Gln Glu Val Thr Arg
20 25
<210> 1898
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1898
Gly Leu Lys Pro Asn Ala Ile Tyr Leu Phe Leu Val Arg
1 5 10
<210> 1899
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1899
Gly Leu Leu Ala Leu Arg
1 5
<210> 1900
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1900
Gly Leu Leu Glu Pro Glu Arg
1 5
<210> 1901
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1901
Gly Leu Leu His Ile Phe Tyr Ile Pro Arg
1 5 10
<210> 1902
<211> 24
<212> PRT
<213> Homo sapiens
<400> 1902
Gly Leu Leu Ile Phe Asp Ala Ser Ser Ser Trp Gly Pro Gln Met Ser
1 5 10 15
Ala Ser Val His Leu Asp Ser Lys
20
<210> 1903
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1903
Gly Leu Leu Ser Gly Trp Ala Arg
1 5
<210> 1904
<211> 28
<212> PRT
<213> Homo sapiens
<400> 1904
Gly Leu Leu Thr Gln His Gly Ile Pro Tyr Thr Arg Pro Thr Glu Thr
1 5 10 15
Ser Asn Leu Glu His Leu Gly His Glu Thr Pro Arg
20 25
<210> 1905
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1905
Gly Leu Leu Val Gly Glu Ile Leu Ser Ala Val Leu Ser Gln Glu Gly
1 5 10 15
Ile Asn Ile Leu Thr His Leu Pro Lys
20 25
<210> 1906
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1906
Gly Leu Met Ala Ala Leu Cys Pro His Lys
1 5 10
<210> 1907
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1907
Gly Leu Asn Pro Leu Thr Ser Tyr Val Phe His Val Arg
1 5 10
<210> 1908
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1908
Gly Leu Pro Ala Lys
1 5
<210> 1909
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1909
Gly Leu Pro Leu Lys
1 5
<210> 1910
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1910
Gly Leu Pro Leu Asn Lys
1 5
<210> 1911
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1911
Gly Leu Pro Pro Leu His Ile Tyr Trp Met Asn Ile Glu Leu Glu His
1 5 10 15
Ile Glu Gln Asp Glu Arg
20
<210> 1912
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1912
Gly Leu Gln Asp Glu Asp Gly Tyr Arg
1 5
<210> 1913
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1913
Gly Leu Gln Val Ala Leu Glu Glu Phe His Lys
1 5 10
<210> 1914
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1914
Gly Leu Gln Tyr Ala Ala Gln Glu Gly Leu Leu Ala Leu Gln Ser Glu
1 5 10 15
Leu Leu Arg
<210> 1915
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1915
Gly Leu Ser Ala Ile Arg
1 5
<210> 1916
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1916
Gly Leu Ser Tyr Arg
1 5
<210> 1917
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1917
Gly Leu Thr Glu Phe Val Glu Pro Ile Ile Gln Ile Lys
1 5 10
<210> 1918
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1918
Gly Leu Thr Leu His Leu Lys
1 5
<210> 1919
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1919
Gly Leu Thr Leu Arg
1 5
<210> 1920
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1920
Gly Leu Thr Ser Val Ile Asn Gln Lys
1 5
<210> 1921
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1921
Gly Leu Thr Thr Arg Pro Gly Ser Gly Leu Thr Asn Ile Lys
1 5 10
<210> 1922
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1922
Gly Leu Val Gly Ser Lys
1 5
<210> 1923
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1923
Gly Leu Val Leu Gly Pro Ile His Lys
1 5
<210> 1924
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1924
Gly Leu Val Leu Ser Gly Val Leu His Lys
1 5 10
<210> 1925
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1925
Gly Leu Val Arg Glu Ala Arg
1 5
<210> 1926
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1926
Gly Leu Val Val Asn Ala Ser Arg
1 5
<210> 1927
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1927
Gly Leu Tyr Asp Val Val Ser Val Leu Arg
1 5 10
<210> 1928
<211> 28
<212> PRT
<213> Homo sapiens
<400> 1928
Gly Met Ala Asp Gln Asp Gly Leu Lys Pro Thr Ile Asp Lys Pro Ser
1 5 10 15
Glu Asp Ser Pro Pro Leu Glu Met Leu Gly Pro Arg
20 25
<210> 1929
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1929
Gly Met Ala Phe Leu His Thr Leu Glu Pro Leu Ile Pro Arg
1 5 10
<210> 1930
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1930
Gly Met Ala Leu Phe Gly Glu Gly Lys
1 5
<210> 1931
<211> 15
<212> PRT
<213> Homo sapiens
<400> 1931
Gly Met Ala Leu Phe Gly Glu Gly Lys Ala Glu Phe Thr Gly Arg
1 5 10 15
<210> 1932
<211> 21
<212> PRT
<213> Homo sapiens
<400> 1932
Gly Met Asp Ser Cys Lys Gly Asp Ser Gly Gly Ala Phe Ala Val Gln
1 5 10 15
Asp Pro Asn Asp Lys
20
<210> 1933
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1933
Gly Met Leu Arg Glu Asp Ala Val Leu Glu Tyr Leu Lys
1 5 10
<210> 1934
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1934
Gly Met Ser Ile Ser Arg Pro Asn Ala Val Val Gly Arg
1 5 10
<210> 1935
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1935
Gly Met Thr Asn Ile Asn Asp Gly Leu Leu Arg
1 5 10
<210> 1936
<211> 23
<212> PRT
<213> Homo sapiens
<400> 1936
Gly Met Thr Arg Pro Leu Ser Thr Leu Ile Ser Ser Ser Gln Ser Cys
1 5 10 15
Gln Tyr Thr Leu Asp Ala Lys
20
<210> 1937
<211> 35
<212> PRT
<213> Homo sapiens
<400> 1937
Gly Met Val Leu Asp Glu Asn Tyr Asn Asn Leu Ala Asn Ala Val Ile
1 5 10 15
Ser Val Ser Gly Ile Asn His Asp Val Thr Ser Gly Asp His Gly Asp
20 25 30
Tyr Phe Arg
35
<210> 1938
<211> 22
<212> PRT
<213> Homo sapiens
<400> 1938
Gly Asn Asp Asp His Trp Ile Val Asp Thr Asp Tyr Asp Thr Tyr Ala
1 5 10 15
Val Gln Tyr Ser Cys Arg
20
<210> 1939
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1939
Gly Asn Asp Ile Ile Ala Ala Ala Lys
1 5
<210> 1940
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1940
Gly Asn Phe His Ala Val Tyr Arg Asp Asp Leu Lys
1 5 10
<210> 1941
<211> 33
<212> PRT
<213> Homo sapiens
<400> 1941
Gly Asn Phe Leu Ala Ala Asn Asp Gln Glu Leu Asp Cys Asp Ile Leu
1 5 10 15
Gln Leu Glu Tyr Val Gly Gly Ile Ser Met Leu Ile Val Val Pro His
20 25 30
Lys
<210> 1942
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1942
Gly Asn Leu Cys Val Asn Leu Met Arg
1 5
<210> 1943
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1943
Gly Asn Leu Val Ser Ile His Asn Phe Asn Ile Asn Tyr Arg
1 5 10
<210> 1944
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1944
Gly Asn Pro Ala Val Ser Tyr Val Arg
1 5
<210> 1945
<211> 61
<212> PRT
<213> Homo sapiens
<400> 1945
Gly Asn Pro Glu Gln Thr Pro Val Leu Lys Pro Glu Glu Glu Ala Pro
1 5 10 15
Ala Pro Glu Val Gly Ala Ser Lys Pro Glu Gly Ile Asp Ser Arg Pro
20 25 30
Glu Thr Leu His Pro Gly Arg Pro Gln Pro Pro Ala Glu Glu Glu Leu
35 40 45
Cys Ser Gly Lys Pro Phe Asp Ala Phe Thr Asp Leu Lys
50 55 60
<210> 1946
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1946
Gly Asn Pro Pro Ile Tyr Arg
1 5
<210> 1947
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1947
Gly Asn Gln Gly Phe Asn Asn Asn Trp Leu Arg
1 5 10
<210> 1948
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1948
Gly Asn Thr Glu Gly Leu Gln Lys
1 5
<210> 1949
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1949
Gly Asn Val Ala Thr Glu Ile Ser Thr Glu Arg
1 5 10
<210> 1950
<211> 25
<212> PRT
<213> Homo sapiens
<400> 1950
Gly Asn Val Ala Val Thr Val Ser Gly His Thr Cys Gln His Trp Ser
1 5 10 15
Ala Gln Thr Pro His Thr His Asn Arg
20 25
<210> 1951
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1951
Gly Pro Ala Tyr Gly Leu Ser Arg
1 5
<210> 1952
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1952
Gly Pro Asp Gly Leu Thr Ala Phe Glu Ala Thr Asp Asn Gln Ala Ile
1 5 10 15
Lys
<210> 1953
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1953
Gly Pro Asp Pro Ser Ser Pro Ala Phe Arg
1 5 10
<210> 1954
<211> 12
<212> PRT
<213> Homo sapiens
<400> 1954
Gly Pro Asp Val Leu Thr Ala Thr Val Ser Gly Lys
1 5 10
<210> 1955
<211> 23
<212> PRT
<213> Homo sapiens
<400> 1955
Gly Pro Glu Glu Glu His Leu Gly Ile Leu Gly Pro Val Ile Trp Ala
1 5 10 15
Glu Val Gly Asp Thr Ile Arg
20
<210> 1956
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1956
Gly Pro Glu Val Gln Leu Val Ala His Ser Pro Trp Leu Lys
1 5 10
<210> 1957
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1957
Gly Pro Glu Val Gln Leu Val Ala His Ser Pro Trp Leu Lys Asp Ser
1 5 10 15
Leu Ser Arg
<210> 1958
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1958
Gly Pro Gly Gly Val Trp Ala Ala Lys Leu Ile Ser Arg
1 5 10
<210> 1959
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1959
Gly Pro Gly Pro Gly Gly Pro Gly Gly Ala Gly Val Ala Arg
1 5 10
<210> 1960
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1960
Gly Pro His Ala Leu Gly Ala Pro Ser Leu Leu Leu Thr Gly Thr Gln
1 5 10 15
Leu Tyr Gly Arg
20
<210> 1961
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1961
Gly Pro His Lys Ala Asp Ser Ile Gln Gly Thr Ala Arg
1 5 10
<210> 1962
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1962
Gly Pro Ile Leu Lys
1 5
<210> 1963
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1963
Gly Pro Leu Asp Gln Leu Glu Lys
1 5
<210> 1964
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1964
Gly Pro Leu Glu His Leu Tyr Ser Leu His Ile Pro Asn Cys Asp Lys
1 5 10 15
<210> 1965
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1965
Gly Pro Leu Lys Leu Lys
1 5
<210> 1966
<211> 5
<212> PRT
<213> Homo sapiens
<400> 1966
Gly Pro Leu Leu Lys
1 5
<210> 1967
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1967
Gly Pro Leu Leu Lys Lys
1 5
<210> 1968
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1968
Gly Pro Leu Leu Asn Lys
1 5
<210> 1969
<211> 19
<212> PRT
<213> Homo sapiens
<400> 1969
Gly Pro Leu Leu Val Gln Asp Val Val Phe Thr Asp Glu Met Ala His
1 5 10 15
Phe Asp Arg
<210> 1970
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1970
Gly Pro Leu Gln Leu Glu Arg
1 5
<210> 1971
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1971
Gly Pro Arg Pro Phe His Cys Arg
1 5
<210> 1972
<211> 7
<212> PRT
<213> Homo sapiens
<400> 1972
Gly Pro Thr Gln Glu Phe Lys
1 5
<210> 1973
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1973
Gly Pro Thr Gln Glu Phe Lys Lys
1 5
<210> 1974
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1974
Gly Pro Val Phe Val Lys Pro Lys
1 5
<210> 1975
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1975
Gly Pro Val Leu Ala Trp Ile Asn Ala Val Ser Ala Phe Arg
1 5 10
<210> 1976
<211> 26
<212> PRT
<213> Homo sapiens
<400> 1976
Gly Pro Val Leu Pro Pro Glu Ser Phe Val Val Leu His Arg Pro Asn
1 5 10 15
Gln Asp Gln Ile Leu Thr Asn Leu Ser Lys
20 25
<210> 1977
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1977
Gly Pro Val Leu Gln Leu His Asp Leu Lys
1 5 10
<210> 1978
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1978
Gly Pro Val Leu Gln Leu His Asp Leu Lys Arg
1 5 10
<210> 1979
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1979
Gly Pro Tyr Glu Ser Gly Ser Gly His Ser Ser Gly Leu Gly His Arg
1 5 10 15
<210> 1980
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1980
Gly Gln Glu Leu Cys Ala Asp Tyr Ser Glu Asn Thr Phe Thr Glu Tyr
1 5 10 15
Lys
<210> 1981
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1981
Gly Gln Glu Leu Cys Ala Asp Tyr Ser Glu Asn Thr Phe Thr Glu Tyr
1 5 10 15
Lys Lys
<210> 1982
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1982
Gly Gln Glu Ser Ser Thr Asp Ile Lys
1 5
<210> 1983
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1983
Gly Gln Gly Ser Ser Pro Val Ala Met Gln Lys
1 5 10
<210> 1984
<211> 14
<212> PRT
<213> Homo sapiens
<400> 1984
Gly Gln Gly Thr Leu Ser Val Val Thr Met Tyr His Ala Lys
1 5 10
<210> 1985
<211> 23
<212> PRT
<213> Homo sapiens
<400> 1985
Gly Gln His Val Pro Gly Ser Pro Phe Gln Phe Thr Val Gly Pro Leu
1 5 10 15
Gly Glu Gly Gly Ala His Lys
20
<210> 1986
<211> 18
<212> PRT
<213> Homo sapiens
<400> 1986
Gly Gln Ile His Leu Asp Pro Gln Gln Asp Tyr Gln Leu Leu Gln Val
1 5 10 15
Gln Arg
<210> 1987
<211> 8
<212> PRT
<213> Homo sapiens
<400> 1987
Gly Gln Ile Val Phe Met Asn Arg
1 5
<210> 1988
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1988
Gly Gln Ile Val Phe Met Asn Arg Glu Pro Lys
1 5 10
<210> 1989
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1989
Gly Gln Lys Gly Glu Pro Gly Asp Ile Lys
1 5 10
<210> 1990
<211> 20
<212> PRT
<213> Homo sapiens
<400> 1990
Gly Gln Pro Ser Val Leu Gln Val Val Asn Leu Pro Ile Val Glu Arg
1 5 10 15
Pro Val Cys Lys
20
<210> 1991
<211> 17
<212> PRT
<213> Homo sapiens
<400> 1991
Gly Gln Ser Ile Ser Val Thr Ser Ile Arg Pro Cys Ala Ala Glu Thr
1 5 10 15
Gln
<210> 1992
<211> 9
<212> PRT
<213> Homo sapiens
<400> 1992
Gly Gln Thr Leu Leu Ala Val Ala Lys
1 5
<210> 1993
<211> 13
<212> PRT
<213> Homo sapiens
<400> 1993
Gly Gln Val Gly Ser Glu Gln His Ser Asp Ile Val Lys
1 5 10
<210> 1994
<211> 16
<212> PRT
<213> Homo sapiens
<400> 1994
Gly Gln Val Pro Glu Asn Glu Ala Asn Val Val Ile Thr Thr Leu Lys
1 5 10 15
<210> 1995
<211> 11
<212> PRT
<213> Homo sapiens
<400> 1995
Gly Gln Val Val Lys Gly Ser Val Phe Leu Arg
1 5 10
<210> 1996
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1996
Gly Gln Val Val Pro Ala Leu Asn Glu Lys
1 5 10
<210> 1997
<211> 6
<212> PRT
<213> Homo sapiens
<400> 1997
Gly Gln Trp Val Thr Lys
1 5
<210> 1998
<211> 10
<212> PRT
<213> Homo sapiens
<400> 1998
Gly Gln Tyr Cys Tyr Glu Leu Asp Glu Lys
1 5 10
<210> 1999
<211> 29
<212> PRT
<213> Homo sapiens
<400> 1999
Gly Arg Phe Pro Leu Tyr Asn Leu Gly Phe Gly His Asn Val Asp Phe
1 5 10 15
Asn Phe Leu Glu Val Met Ser Met Glu Asn Asn Gly Arg
20 25
<210> 2000
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2000
Gly Arg Leu Asp Ser Glu Leu Arg
1 5
<210> 2001
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2001
Gly Arg Pro Gly Pro Gln Pro Trp Cys Ala Thr Thr Pro Asn Phe Asp
1 5 10 15
Gln Asp Gln Arg
20
<210> 2002
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2002
Gly Arg Pro Thr Ser Thr Asn Pro Ile Ala Ser Ile Phe Ala Trp Thr
1 5 10 15
Arg
<210> 2003
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2003
Gly Ser Ala Ala Asp Ser Glu Glu Ser Pro Ala Ile Glu Ala Ile His
1 5 10 15
Leu Leu Arg
<210> 2004
<211> 37
<212> PRT
<213> Homo sapiens
<400> 2004
Gly Ser Ala Glu Ala Glu Leu Met Ser Val Val Pro Val Phe Tyr Val
1 5 10 15
Phe His Tyr Leu Glu Thr Gly Asn His Trp Asn Ile Phe His Ser Asp
20 25 30
Pro Leu Ile Glu Lys
35
<210> 2005
<211> 58
<212> PRT
<213> Homo sapiens
<400> 2005
Gly Ser Ala Gly His Trp Thr Ser Glu Ser Ser Val Ser Gly Ser Thr
1 5 10 15
Gly Gln Trp His Ser Glu Ser Gly Ser Phe Arg Pro Asp Ser Pro Gly
20 25 30
Ser Gly Asn Ala Arg Pro Asn Asn Pro Asp Trp Gly Thr Phe Glu Glu
35 40 45
Val Ser Gly Asn Val Ser Pro Gly Thr Arg
50 55
<210> 2006
<211> 59
<212> PRT
<213> Homo sapiens
<400> 2006
Gly Ser Ala Gly His Trp Thr Ser Glu Ser Ser Val Ser Gly Ser Thr
1 5 10 15
Gly Gln Trp His Ser Glu Ser Gly Ser Phe Arg Pro Asp Ser Pro Gly
20 25 30
Ser Gly Asn Ala Arg Pro Asn Asn Pro Asp Trp Gly Thr Phe Glu Glu
35 40 45
Val Ser Gly Asn Val Ser Pro Gly Thr Arg Arg
50 55
<210> 2007
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2007
Gly Ser Ala Pro Pro Gly Pro Val Pro Glu Gly Ser Ile Arg
1 5 10
<210> 2008
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2008
Gly Ser Glu Ala Ile Asn Ala Pro Gly Asp Asn Pro Ala Lys
1 5 10
<210> 2009
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2009
Gly Ser Glu Met Val Val Ala Gly Lys
1 5
<210> 2010
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2010
Gly Ser Glu Ser Gly Ile Phe Thr Asn Thr Lys
1 5 10
<210> 2011
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2011
Gly Ser Phe Glu Phe Pro Val Gly Asp Ala Val Ser Lys
1 5 10
<210> 2012
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2012
Gly Ser Phe Pro Trp Gln Ala Lys
1 5
<210> 2013
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2013
Gly Ser Phe Thr Phe Gln Ala Ala Leu His His Asp Gly Arg
1 5 10
<210> 2014
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2014
Gly Ser Gly Ser Gly Gln Ser Pro Ser Ser Gly Gln His Gly Thr Gly
1 5 10 15
Phe Gly Arg
<210> 2015
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2015
Gly Ser Gly Thr Ala Glu Val Glu Leu Lys Lys
1 5 10
<210> 2016
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2016
Gly Ser Leu His Ala Asn Gly Arg
1 5
<210> 2017
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2017
Gly Ser Leu Val Gln Ala Ser Glu Ala Asn Leu Gln Ala Ala Gln Asp
1 5 10 15
Phe Val Arg
<210> 2018
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2018
Gly Ser Pro Ala Ile Asn Val Ala Val His Val Phe Arg
1 5 10
<210> 2019
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2019
Gly Ser Pro Ala Ile Asn Val Ala Val His Val Phe Arg Lys
1 5 10
<210> 2020
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2020
Gly Ser Gln Thr Gln Ser His Pro Asp Leu Gly Thr Glu Gly Cys Trp
1 5 10 15
Asp Gln Leu Ser Ala Pro Arg
20
<210> 2021
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2021
Gly Ser Gln Tyr Trp Arg
1 5
<210> 2022
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2022
Gly Ser Ser Ala Gly Gly Leu Gln His Leu Val Ser Ile Arg
1 5 10
<210> 2023
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2023
Gly Ser Ser Gly Leu Glu Glu Lys
1 5
<210> 2024
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2024
Gly Ser Ser Thr Trp Leu Thr Ala Phe Val Leu Lys
1 5 10
<210> 2025
<211> 27
<212> PRT
<213> Homo sapiens
<400> 2025
Gly Ser Ser Thr Trp Leu Thr Ala Phe Val Leu Lys Val Leu Ser Leu
1 5 10 15
Ala Gln Glu Gln Val Gly Gly Ser Pro Glu Lys
20 25
<210> 2026
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2026
Gly Ser Ser Val His Gln Asp Phe Leu Gly Phe Tyr Val Leu Asp Ser
1 5 10 15
His Arg
<210> 2027
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2027
Gly Ser Ser Val Ile His Cys Asp Ala Asp Ser Lys
1 5 10
<210> 2028
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2028
Gly Ser Thr Gly Val Ala Ala Ala Ala Gly Leu His Arg
1 5 10
<210> 2029
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2029
Gly Ser Thr Ser His His Leu Val Ser Arg
1 5 10
<210> 2030
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2030
Gly Ser Val Phe Leu Arg
1 5
<210> 2031
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2031
Gly Ser Val Leu Ser Arg
1 5
<210> 2032
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2032
Gly Ser Val Leu Tyr His Leu Ala Val Lys
1 5 10
<210> 2033
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2033
Gly Ser Val Gln Tyr Leu Pro Asp Leu Asp Asp Lys
1 5 10
<210> 2034
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2034
Gly Ser Val Gln Tyr Leu Pro Asp Leu Asp Asp Lys Asn Ser Gln Glu
1 5 10 15
Lys
<210> 2035
<211> 25
<212> PRT
<213> Homo sapiens
<400> 2035
Gly Ser Trp Phe Leu Thr Gly Val Leu Gly Ser Gln Pro Val Gly Gly
1 5 10 15
Gln Ala His Met Val Leu Val Thr Lys
20 25
<210> 2036
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2036
Gly Ser Trp Val Asn Lys
1 5
<210> 2037
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2037
Gly Ser Trp Val Asn Lys Phe Pro Val Glu Met Thr His Asn His Asn
1 5 10 15
Phe Arg
<210> 2038
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2038
Gly Ser Trp Tyr Ser Met Arg
1 5
<210> 2039
<211> 39
<212> PRT
<213> Homo sapiens
<400> 2039
Gly Ser Tyr Gly Ser Gly Gly Ser Ser Tyr Gly Ser Gly Gly Gly Ser
1 5 10 15
Tyr Gly Ser Gly Gly Gly Gly Gly Gly His Gly Ser Tyr Gly Ser Gly
20 25 30
Ser Ser Ser Gly Gly Tyr Arg
35
<210> 2040
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2040
Gly Thr Asp Tyr His Lys Gln Pro Trp Gln Ala Lys
1 5 10
<210> 2041
<211> 29
<212> PRT
<213> Homo sapiens
<400> 2041
Gly Thr Glu Ala Ala Ala Val Pro Glu Val Glu Leu Ser Asp Gln Pro
1 5 10 15
Glu Asn Thr Phe Leu His Pro Ile Ile Gln Ile Asp Arg
20 25
<210> 2042
<211> 22
<212> PRT
<213> Homo sapiens
<400> 2042
Gly Thr Glu Ala Ala Gly Ala Met Phe Leu Glu Ala Ile Pro Met Ser
1 5 10 15
Ile Pro Pro Glu Val Lys
20
<210> 2043
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2043
Gly Thr Glu Asp Glu Leu Asp Lys
1 5
<210> 2044
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2044
Gly Thr Glu His Ala Ser Ala Ser Ala Asn Gly His Val Ser Tyr Ser
1 5 10 15
Ala Val Ser Arg
20
<210> 2045
<211> 29
<212> PRT
<213> Homo sapiens
<400> 2045
Gly Thr Glu Leu Gln His Leu Leu His Ala Val Val Pro Gly Pro Trp
1 5 10 15
Gln Glu Asp Val Ala Asp Ala Glu Glu Cys Ala Gly Arg
20 25
<210> 2046
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2046
Gly Thr Phe Ala Thr Leu Ser Glu Leu His Cys Asp Lys
1 5 10
<210> 2047
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2047
Gly Thr Gly Glu Asn Tyr Arg
1 5
<210> 2048
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2048
Gly Thr His Cys Asn Gln Val Glu Val Ile Ala Thr Leu Lys
1 5 10
<210> 2049
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2049
Gly Thr His Val Asp Leu Gly Leu Ala Ser Ala Asn Val Asp Phe Ala
1 5 10 15
Phe Ser Leu Tyr Lys
20
<210> 2050
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2050
Gly Thr Lys Pro Ile Asp Leu Gly Asn Gly Gln Thr Arg
1 5 10
<210> 2051
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2051
Gly Thr Leu Asp Pro Val Glu Lys
1 5
<210> 2052
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2052
Gly Thr Leu Leu Ala Leu Glu Arg
1 5
<210> 2053
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2053
Gly Thr Leu Thr Glu Gly Gly Thr Gln Lys
1 5 10
<210> 2054
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2054
Gly Thr Ser Gln Asn Asp Pro Asn Trp Val Val Arg
1 5 10
<210> 2055
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2055
Gly Thr Ser Ser Thr Thr Thr Thr Gly Lys Lys
1 5 10
<210> 2056
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2056
Gly Thr Val Glu Pro Gln Leu Glu Ala Arg
1 5 10
<210> 2057
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2057
Gly Thr Val Phe Phe Asp Glu Phe Thr Phe Val Lys
1 5 10
<210> 2058
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2058
Gly Thr Val Gln Ala Leu His Ala Thr Gly Ala Arg
1 5 10
<210> 2059
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2059
Gly Thr Val Tyr Asn Tyr Arg
1 5
<210> 2060
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2060
Gly Thr Trp Thr Gln Pro Phe Asp Leu Ala Ser Thr Arg
1 5 10
<210> 2061
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2061
Gly Thr Tyr Ile Pro Val Pro Ile Val Ser Glu Leu Gln Ser Gly Lys
1 5 10 15
<210> 2062
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2062
Gly Thr Tyr Ser Thr Thr Val Thr Gly Arg
1 5 10
<210> 2063
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2063
Gly Val Ala Leu Ala Asp Phe Asn Arg
1 5
<210> 2064
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2064
Gly Val Ala Ser Leu Phe Ala Gly Arg
1 5
<210> 2065
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2065
Gly Val Cys Glu Glu Thr Ser Gly Ala Tyr Glu Lys
1 5 10
<210> 2066
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2066
Gly Val Glu Leu Lys
1 5
<210> 2067
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2067
Gly Val Phe Val Leu Asn Lys
1 5
<210> 2068
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2068
Gly Val Phe Val Leu Asn Lys Lys
1 5
<210> 2069
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2069
Gly Val Gly Ala Ala Ala Thr Ala Val Thr Gln Ala Leu Asn Glu Leu
1 5 10 15
Leu Gln His Val Lys
20
<210> 2070
<211> 27
<212> PRT
<213> Homo sapiens
<400> 2070
Gly Val Gly Gly Ser Gln Pro Pro Asp Ile Asp Lys Thr Glu Leu Val
1 5 10 15
Glu Pro Thr Glu Tyr Leu Val Val His Leu Lys
20 25
<210> 2071
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2071
Gly Val Gly Gln Ala Ala Ile Arg
1 5
<210> 2072
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2072
Gly Val Gly Trp Ser His Pro Leu Pro Gln Cys Glu Ile Val Lys
1 5 10 15
<210> 2073
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2073
Gly Val His Tyr Ile Ser Val Ser Ala Thr Arg
1 5 10
<210> 2074
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2074
Gly Val Ile Ile Lys
1 5
<210> 2075
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2075
Gly Val Ile Ser Ile Pro Arg
1 5
<210> 2076
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2076
Gly Val Leu His Asn Glu Val Lys
1 5
<210> 2077
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2077
Gly Val Leu Leu Lys
1 5
<210> 2078
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2078
Gly Val Asn Leu Pro Gly Ala Ala Val Asp Leu Pro Ala Val Ser Glu
1 5 10 15
Lys
<210> 2079
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2079
Gly Val Asn Leu Gln Glu Phe Leu Asn Val Thr Ser Val His Leu Phe
1 5 10 15
Lys
<210> 2080
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2080
Gly Val Pro Ile Pro Asn Lys
1 5
<210> 2081
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2081
Gly Val Pro Ile Pro Asn Lys Val Ile Phe Ile Arg
1 5 10
<210> 2082
<211> 34
<212> PRT
<213> Homo sapiens
<400> 2082
Gly Val Gln Ile Pro Leu Pro Glu Gly Ile Asn Phe Val His Glu Val
1 5 10 15
Val Thr Asn His Ala Gly Phe Leu Thr Ile Gly Ala Asp Leu His Phe
20 25 30
Ala Lys
<210> 2083
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2083
Gly Val Ser His Gly Gln Phe Phe Asp Gln His Leu Lys
1 5 10
<210> 2084
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2084
Gly Val Thr Phe Leu Leu Arg
1 5
<210> 2085
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2085
Gly Val Thr Ile Pro Tyr Arg Pro Lys Pro Ser Ser Ser Pro Val Ile
1 5 10 15
Phe Ala Gly Gly Gln Asp Arg
20
<210> 2086
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2086
Gly Val Thr Ser Val Ser Gln Ile Phe His Ser Pro Asp Leu Ala Ile
1 5 10 15
Arg
<210> 2087
<211> 27
<212> PRT
<213> Homo sapiens
<400> 2087
Gly Val Tyr Leu Phe Ala Val Ser Val Glu Phe Gly Pro Gly Pro Gly
1 5 10 15
Thr Gly Gln Leu Val Phe Gly Gly His His Arg
20 25
<210> 2088
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2088
Gly Val Tyr Leu Leu Lys
1 5
<210> 2089
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2089
Gly Val Tyr Ser Ser Asp Val Phe Asp Ile Phe Pro Gly Thr Tyr Gln
1 5 10 15
Thr Leu Glu Met Phe Pro Arg
20
<210> 2090
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2090
Gly Trp His Trp Val Gly Ala His Thr Leu Gly His Asn Ser Arg
1 5 10 15
<210> 2091
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2091
Gly Trp Val Asp Leu Phe Val Pro Lys
1 5
<210> 2092
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2092
Gly Trp Val Thr Asp Gly Phe Ser Ser Leu Lys
1 5 10
<210> 2093
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2093
Gly Tyr Ala Ile Gly Tyr Gly Ile Gly Ser Pro His Ala Gln Thr Ile
1 5 10 15
Lys
<210> 2094
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2094
Gly Tyr Ala Trp Gly Leu Asn Glu Leu Lys Pro Ile Ser Lys
1 5 10
<210> 2095
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2095
Gly Tyr Phe Thr His His His Gln Arg
1 5
<210> 2096
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2096
Gly Tyr Gly Phe Tyr Thr Lys
1 5
<210> 2097
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2097
Gly Tyr Gly Asn Ser Asp Tyr Lys
1 5
<210> 2098
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2098
Gly Tyr Gly Asn Ser Asp Tyr Lys Arg
1 5
<210> 2099
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2099
Gly Tyr His Leu Asn Glu Glu Gly Thr Arg
1 5 10
<210> 2100
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2100
Gly Tyr His Leu Val Gly Lys
1 5
<210> 2101
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2101
Gly Tyr Ile Leu Val Gly Gln Ala Lys
1 5
<210> 2102
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2102
Gly Tyr Leu Val Leu Lys
1 5
<210> 2103
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2103
Gly Tyr Ser Phe Thr Thr Thr Ala Glu Arg
1 5 10
<210> 2104
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2104
Gly Tyr Ser Ile Phe Ser Tyr Ala Thr Lys
1 5 10
<210> 2105
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2105
Gly Tyr Ser Ile Phe Ser Tyr Ala Thr Lys Arg
1 5 10
<210> 2106
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2106
Gly Tyr Thr Leu Ala Asp Asn Gly Lys
1 5
<210> 2107
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2107
Gly Tyr Thr Gln Gln Leu Ala Phe Arg
1 5
<210> 2108
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2108
Gly Tyr Val Ile Ile Lys Pro Leu Val Trp Val
1 5 10
<210> 2109
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2109
Gly Tyr Trp Ser Asp Trp Ser Glu Glu Ala Ser Gly Ile Thr Tyr Glu
1 5 10 15
Asp Arg Pro Ser Lys
20
<210> 2110
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2110
His Ala Asp Pro Asp Phe Thr Arg
1 5
<210> 2111
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2111
His Ala Asp Pro Asp Phe Thr Arg Lys
1 5
<210> 2112
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2112
His Ala Glu Met Val His Thr Gly Leu Lys
1 5 10
<210> 2113
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2113
His Ala Phe Ile Leu Gln Asp Thr Lys
1 5
<210> 2114
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2114
His Ala Ile Ile Leu Leu Thr Asp Gly Lys
1 5 10
<210> 2115
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2115
His Cys Leu Val Thr Val Glu Lys
1 5
<210> 2116
<211> 32
<212> PRT
<213> Homo sapiens
<400> 2116
His Asp Gly Asn Met Val Phe Ser Pro Phe Gly Met Ser Leu Ala Met
1 5 10 15
Thr Gly Leu Met Leu Gly Ala Thr Gly Pro Thr Glu Thr Gln Ile Lys
20 25 30
<210> 2117
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2117
His Asp Leu Gly His Phe Met Leu Arg
1 5
<210> 2118
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2118
His Asp Thr Ser Leu Lys Pro Ile Ser Val Ser Tyr Asn Pro Ala Thr
1 5 10 15
Ala Lys
<210> 2119
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2119
His Glu Glu Ala Pro Gly His Arg Pro Thr Thr Asn Pro Asn Ala Ser
1 5 10 15
Lys
<210> 2120
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2120
His Glu Gly Ser Phe Ile Gln Gly Ala Glu Lys
1 5 10
<210> 2121
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2121
His Glu Leu Thr Asp Glu Glu Leu Gln Ser Leu Phe Thr Asn Phe Ala
1 5 10 15
Asn Val Val Asp Lys
20
<210> 2122
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2122
His Glu Gln Asp Met Val Asn Gly Ile Met Leu Ser Val Glu Lys
1 5 10 15
<210> 2123
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2123
His Glu Val Ile Asn Ile Asn Leu Lys
1 5
<210> 2124
<211> 35
<212> PRT
<213> Homo sapiens
<400> 2124
His Phe Glu Ile Glu Val Asp Ile Phe Glu Pro Gln Gly Ile Ser Met
1 5 10 15
Leu Asp Ala Glu Ala Ser Phe Ile Thr Asn Asp Leu Leu Gly Ser Ala
20 25 30
Leu Thr Lys
35
<210> 2125
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2125
His Phe Gln Asn Leu Gly Lys
1 5
<210> 2126
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2126
His Phe Gln Val Pro Val Phe Lys
1 5
<210> 2127
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2127
His Phe Val Ala Leu Ser Thr Asn Thr Thr Lys
1 5 10
<210> 2128
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2128
His Phe Val Ile Asn Leu Ile Gly Asp Phe Glu Val Ala Glu Lys
1 5 10 15
<210> 2129
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2129
His Phe Trp Gln Gln Asp Glu Pro Pro Gln Ser Pro Trp Asp Arg
1 5 10 15
<210> 2130
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2130
His Gly Ala Thr Val Leu Thr Ala Leu Gly Gly Ile Leu Lys
1 5 10
<210> 2131
<211> 22
<212> PRT
<213> Homo sapiens
<400> 2131
His Gly Glu Ser Gly Ser Met Ala Val Phe His Gln Thr Gln Gly Pro
1 5 10 15
Ser Tyr Ser Glu Ser Lys
20
<210> 2132
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2132
His Gly Gly Gly Gly Gly Gly Phe Gly Gly Gly Gly Phe Gly Ser Arg
1 5 10 15
<210> 2133
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2133
His Gly Gly Leu Phe His Glu Asn Met Arg
1 5 10
<210> 2134
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2134
His Gly Gly Leu Tyr His Glu Asn Met Arg
1 5 10
<210> 2135
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2135
His Gly Ile Val Glu Asp Trp Asp Leu Met Glu Arg
1 5 10
<210> 2136
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2136
His Gly Leu Gln Thr Val Gly Ile Phe Arg
1 5 10
<210> 2137
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2137
His Gly Leu Ser Asn Ser Ile Tyr Val Phe Val Arg
1 5 10
<210> 2138
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2138
His Gly Leu Tyr Asn Leu Lys
1 5
<210> 2139
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2139
His Gly Asn Thr Asp Ser Glu Gly Ile Val Glu Val Lys
1 5 10
<210> 2140
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2140
His Gly Pro Gly Gln Met Leu Phe Gln Asn Gly Asp Lys
1 5 10
<210> 2141
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2141
His Gly Thr Asp Asp Gly Val Val Trp Met Asn Trp Lys
1 5 10
<210> 2142
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2142
His Gly Thr Asp Asp Gly Val Val Trp Met Asn Trp Lys Gly Ser Trp
1 5 10 15
Tyr Ser Met Arg
20
<210> 2143
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2143
His Gly Thr Val Ser Ser Phe Val Ala Lys
1 5 10
<210> 2144
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2144
His Gly Val Gln Glu Leu Glu Ile Glu Leu Gln Ser Gln Leu Ser Lys
1 5 10 15
<210> 2145
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2145
His His Ala Ala Tyr Val Asn Asn Leu Asn Val Thr Glu Glu Lys
1 5 10 15
<210> 2146
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2146
His His Gly Pro Gln Thr Leu Tyr Leu Pro Val Thr Leu Ser Ser Ile
1 5 10 15
Pro Val Phe Gln Arg
20
<210> 2147
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2147
His His Gly Pro Thr Ile Thr Ala Lys
1 5
<210> 2148
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2148
His His Leu Glu Ala Val Gln Asn Ala Lys
1 5 10
<210> 2149
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2149
His His Leu Gly Leu Glu Glu Pro Lys
1 5
<210> 2150
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2150
His His Leu Gly Leu Glu Glu Pro Lys Lys
1 5 10
<210> 2151
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2151
His His Pro Asp Phe Glu Val Phe Val Phe Asp Val Gly Gln Lys
1 5 10 15
<210> 2152
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2152
His His Pro Glu His Phe Ser Gly Arg Pro Arg
1 5 10
<210> 2153
<211> 30
<212> PRT
<213> Homo sapiens
<400> 2153
His Ile Ala Asp Leu Ala Gly Asn Ser Glu Val Ile Leu Pro Val Pro
1 5 10 15
Ala Phe Asn Val Ile Asn Gly Gly Ser His Ala Gly Asn Lys
20 25 30
<210> 2154
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2154
His Ile Ala Leu Ser Asn Met Pro Lys
1 5
<210> 2155
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2155
His Ile Leu Ala Asn Phe Lys
1 5
<210> 2156
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2156
His Ile Asn Ile Asp Gln Phe Val Arg
1 5
<210> 2157
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2157
His Ile Gln Asn Ile Asp Ile Gln His Leu Ala Gly Lys
1 5 10
<210> 2158
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2158
His Ile Gln Pro Gly Ala Phe Asp Thr Leu Asp Arg
1 5 10
<210> 2159
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2159
His Ile Ser Leu Thr Leu Pro Ala Thr Phe Arg
1 5 10
<210> 2160
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2160
His Ile Thr Ser Leu Glu Val Ile Lys
1 5
<210> 2161
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2161
His Ile Val Phe Leu Thr Glu Lys Asn Ile Lys
1 5 10
<210> 2162
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2162
His Ile Val Leu Lys Pro Pro Thr Ile Val Thr Gln Val Ile Glu Val
1 5 10 15
Asn Lys
<210> 2163
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2163
His Ile Val Thr Phe Asp Gly Gln Asn Phe Lys
1 5 10
<210> 2164
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2164
His Ile Tyr Ala Ile Ser Ser Ala Ala Leu Ser Ala Ser Tyr Lys
1 5 10 15
<210> 2165
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2165
His Ile Tyr Leu Leu Pro Ser Gly Arg
1 5
<210> 2166
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2166
His Lys Phe Leu Asp Ser Asn Ile Lys
1 5
<210> 2167
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2167
His Lys Leu Gln Val Phe Gln Ala Leu Arg
1 5 10
<210> 2168
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2168
His Leu Asp Ser Val Leu Gln Gln Leu Gln Thr Glu Val Tyr Arg
1 5 10 15
<210> 2169
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2169
His Leu Glu Asp Val Phe Ser Lys
1 5
<210> 2170
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2170
His Leu Glu Ile Asn Pro Asp His Ser Ile Ile Glu Thr Leu Arg
1 5 10 15
<210> 2171
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2171
His Leu Glu Val Asp Val Trp Val Ile Glu Pro Gln Gly Leu Arg
1 5 10 15
<210> 2172
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2172
His Leu Phe Thr Gly Pro Val Leu Ser Lys
1 5 10
<210> 2173
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2173
His Leu Phe Trp Phe Pro Ala Glu Ala Phe His Lys Pro Gly Leu Glu
1 5 10 15
Lys
<210> 2174
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2174
His Leu Ile Asp Ser Leu Ile Asp Phe Leu Asn Phe Pro Arg
1 5 10
<210> 2175
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2175
His Leu Ile Phe Glu Lys
1 5
<210> 2176
<211> 22
<212> PRT
<213> Homo sapiens
<400> 2176
His Leu Ile Ser Thr His Phe Ala Pro Gly Asp Phe Gln Gly Phe Ala
1 5 10 15
Leu Val Asn Pro Gln Arg
20
<210> 2177
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2177
His Leu Ile Val Leu Ile Asn Lys
1 5
<210> 2178
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2178
His Leu Lys Pro Leu Ala Lys
1 5
<210> 2179
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2179
His Leu Gln Ala Gly Ile Leu Lys
1 5
<210> 2180
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2180
His Leu Gln Ala Gly Met Gln Ala Tyr Ile Asp Ile Lys
1 5 10
<210> 2181
<211> 30
<212> PRT
<213> Homo sapiens
<400> 2181
His Leu Gln Pro Gly Met Val Leu Thr Val Glu Pro Gly Ile Tyr Phe
1 5 10 15
Ile Asp His Leu Leu Asp Glu Ala Leu Ala Asp Pro Ala Arg
20 25 30
<210> 2182
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2182
His Leu Gln Pro Gln Pro Tyr Lys
1 5
<210> 2183
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2183
His Leu Ser Ile Ser Val Val Leu Lys
1 5
<210> 2184
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2184
His Leu Ser Leu Leu Thr Thr Leu Ser Asn Arg
1 5 10
<210> 2185
<211> 22
<212> PRT
<213> Homo sapiens
<400> 2185
His Leu Ser Leu Leu Thr Thr Leu Ser Asn Arg Val Cys Ser Gln Tyr
1 5 10 15
Ala Ala Tyr Gly Glu Lys
20
<210> 2186
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2186
His Leu Val Ala Leu Ser Pro Lys
1 5
<210> 2187
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2187
His Leu Val Pro Gly Ala Pro Phe Leu Leu Gln Ala Leu Val Arg
1 5 10 15
<210> 2188
<211> 22
<212> PRT
<213> Homo sapiens
<400> 2188
His Leu Tyr Val Leu Glu Phe Ser Asp His Pro Gly Ile His Glu Pro
1 5 10 15
Leu Glu Pro Glu Val Lys
20
<210> 2189
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2189
His Met Glu Ala Ser Leu Gln Glu Leu Lys
1 5 10
<210> 2190
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2190
His Met Asn Gly Tyr Gly Ser His Thr Phe Lys
1 5 10
<210> 2191
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2191
His Met Gln Ala Asn Pro Glu Pro Pro Lys Lys
1 5 10
<210> 2192
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2192
His Asn Ser Ser Gly Ser Ile Leu Phe Leu Gly Arg
1 5 10
<210> 2193
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2193
His Asn Val Tyr Ile Asn Gly Ile Thr Tyr Thr Pro Val Ser Ser Thr
1 5 10 15
Asn Glu Lys
<210> 2194
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2194
His Pro Ala Leu Phe Lys
1 5
<210> 2195
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2195
His Pro Asp Glu Ala Ala Phe Phe Asp Thr Ala Ser Thr Gly Lys
1 5 10 15
<210> 2196
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2196
His Pro Asp Leu Ser Ile Pro Glu Leu Leu Arg
1 5 10
<210> 2197
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2197
His Pro Asp Met Leu Thr Lys
1 5
<210> 2198
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2198
His Pro Asp Tyr Ser Val Val Leu Leu Leu Arg
1 5 10
<210> 2199
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2199
His Pro Glu Glu Leu Ser Leu Leu Arg
1 5
<210> 2200
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2200
His Pro Phe Leu Thr Ala Leu Lys
1 5
<210> 2201
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2201
His Pro Gly Glu Leu Arg Asn Gly Gln Val Glu Ile Lys
1 5 10
<210> 2202
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2202
His Pro Leu Lys Pro Asp Asn Gln Pro Phe Pro Gln Ser Val Ser Glu
1 5 10 15
Ser Cys Pro Gly Lys
20
<210> 2203
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2203
His Pro Asn Val Phe Gly Phe Cys Arg
1 5
<210> 2204
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2204
His Pro Pro Glu Ala Ser Val Gln Ile His Gln Val Ser Arg
1 5 10
<210> 2205
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2205
His Pro Pro Ser Pro Thr Arg Asp Glu Cys Phe Ala Arg
1 5 10
<210> 2206
<211> 27
<212> PRT
<213> Homo sapiens
<400> 2206
His Pro Pro Val Val Met Asn Gly Ala Val Ala Asp Gly Ile Leu Ala
1 5 10 15
Ser Tyr Ala Thr Gly Ser Ser Val Glu Tyr Arg
20 25
<210> 2207
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2207
His Pro Ser Phe Phe Leu Tyr Arg
1 5
<210> 2208
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2208
His Pro Tyr Phe Tyr Ala Pro Glu Leu Leu Phe Phe Ala Lys
1 5 10
<210> 2209
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2209
His Gln Ala Gln Ile Asp His Tyr Leu Gly Leu Ala Asn Lys
1 5 10
<210> 2210
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2210
His Gln Asp Phe Asn Ser Ala Val Gln Leu Val Glu Asn Phe Cys Arg
1 5 10 15
<210> 2211
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2211
His Gln Asp Gly Ser Tyr Ser Thr Phe Gly Glu Arg
1 5 10
<210> 2212
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2212
His Gln Phe Leu Leu Thr Gly Asp Thr Gln Gly Arg
1 5 10
<210> 2213
<211> 30
<212> PRT
<213> Homo sapiens
<400> 2213
His Gln Gly Thr Ile Thr Val Asn Glu Glu Gly Thr Gln Ala Thr Thr
1 5 10 15
Val Thr Thr Val Gly Phe Met Pro Leu Ser Thr Gln Val Arg
20 25 30
<210> 2214
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2214
His Gln Gly Val Met Val Gly Met Gly Gln Lys
1 5 10
<210> 2215
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2215
His Gln Leu Ser Glu Pro Ala Pro Ala Tyr His Arg
1 5 10
<210> 2216
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2216
His Gln Leu Tyr Ile Asp Glu Thr Val Asn Ser Asn Ile Pro Thr Asn
1 5 10 15
Leu Arg
<210> 2217
<211> 24
<212> PRT
<213> Homo sapiens
<400> 2217
His Gln Met Asp Leu Val Ala Thr Leu Ser Gln Leu Gly Leu Gln Glu
1 5 10 15
Leu Phe Gln Ala Pro Asp Leu Arg
20
<210> 2218
<211> 22
<212> PRT
<213> Homo sapiens
<400> 2218
His Gln Pro Gln Glu Phe Pro Thr Tyr Val Glu Pro Thr Asn Asp Glu
1 5 10 15
Ile Cys Glu Ala Phe Arg
20
<210> 2219
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2219
His Gln Pro Gln Glu Phe Pro Thr Tyr Val Glu Pro Thr Asn Asp Glu
1 5 10 15
Ile Cys Glu Ala Phe Arg Lys
20
<210> 2220
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2220
His Gln Pro Thr Ala Ile Ile Ala Lys
1 5
<210> 2221
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2221
His Gln Gln Thr Val Thr Ile Pro Pro Lys
1 5 10
<210> 2222
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2222
His Gln Ser Pro Ile Asp Ile Leu Asp Gln Tyr Ala Arg
1 5 10
<210> 2223
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2223
His Gln Thr Val Pro Gln Asn Thr Gly Gly Lys
1 5 10
<210> 2224
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2224
His Arg His Pro Asp Glu Ala Ala Phe Phe Asp Thr Ala Ser Thr Gly
1 5 10 15
Lys
<210> 2225
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2225
His Arg Leu Glu Asp Met Glu Gln Ala Leu Ser Pro Ser Val Phe Lys
1 5 10 15
<210> 2226
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2226
His Arg Pro Glu Leu Ile Asp Tyr Gly Lys
1 5 10
<210> 2227
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2227
His Arg Pro Arg Pro Tyr Pro Pro Asn Val Gly Glu Glu Ile Gln Ile
1 5 10 15
Gly His Ile Pro Arg
20
<210> 2228
<211> 24
<212> PRT
<213> Homo sapiens
<400> 2228
His Arg Gln Gly Pro Val Asn Leu Leu Ser Asp Pro Glu Gln Gly Val
1 5 10 15
Glu Val Thr Gly Gln Tyr Glu Arg
20
<210> 2229
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2229
His Ser Ala Gln Pro Trp Ala Asp Phe Thr Leu Leu Gly Ala Arg
1 5 10 15
<210> 2230
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2230
His Ser Gly Glu Glu Asn Phe Tyr Ala Tyr Gly Phe Ser Val Thr Tyr
1 5 10 15
Ser Cys Asp Pro Arg
20
<210> 2231
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2231
His Ser His Glu Ser Gln Asp Leu Arg
1 5
<210> 2232
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2232
His Ser Ile Phe Thr Pro Glu Thr Asn Pro Arg
1 5 10
<210> 2233
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2233
His Ser Ile Gly Tyr Ser Ile Arg
1 5
<210> 2234
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2234
His Ser Ile Thr Asn Pro Leu Ala Val Leu Cys Glu Phe Ile Ser Gln
1 5 10 15
Ser Ile Lys
<210> 2235
<211> 28
<212> PRT
<213> Homo sapiens
<400> 2235
His Ser Leu Pro Asp Leu Pro Tyr Asp Tyr Gly Ala Leu Glu Pro His
1 5 10 15
Ile Asn Ala Gln Ile Met Gln Leu His His Ser Lys
20 25
<210> 2236
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2236
His Ser Pro Gln Glu Ala Pro His Val Gln Tyr Glu Arg
1 5 10
<210> 2237
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2237
His Ser Gln Ala Val Glu Glu Leu Ala Glu Gln Leu Glu Gln Thr Lys
1 5 10 15
<210> 2238
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2238
His Ser Thr Phe Ile Pro Gly Thr Asn Lys
1 5 10
<210> 2239
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2239
His Ser Thr Ile Phe Glu Asn Leu Ala Asn Lys
1 5 10
<210> 2240
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2240
His Ser Thr Ile Phe Glu Asn Leu Ala Asn Lys Ala Asp Arg
1 5 10
<210> 2241
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2241
His Ser Thr Ser Met Phe Phe Arg
1 5
<210> 2242
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2242
His Ser Val Val Lys
1 5
<210> 2243
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2243
His Ser Trp Thr Ile Pro Glu Asp Gly Asn Ser Gln Lys
1 5 10
<210> 2244
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2244
His Ser Tyr Leu His Leu Ala Glu Asn Tyr Leu Ile Arg
1 5 10
<210> 2245
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2245
His Thr Ala Met Val Ser Trp Gly Gly Val Ser Ile Pro Asn Ser Pro
1 5 10 15
Phe Arg
<210> 2246
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2246
His Thr Ala Ser Ala Trp Leu Met Ser Ala Pro Asn Ser Gly Pro His
1 5 10 15
Asn Arg
<210> 2247
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2247
His Thr Phe Met Gly Val Val Ser Leu Gly Ser Pro Ser Gly Glu Val
1 5 10 15
Ser His Pro Arg
20
<210> 2248
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2248
His Thr Phe Thr Leu Ser Leu Pro Arg
1 5
<210> 2249
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2249
His Thr Leu Asn Gln Ile Asp Glu Val Lys
1 5 10
<210> 2250
<211> 42
<212> PRT
<213> Homo sapiens
<400> 2250
His Thr Leu Asn Gln Ile Asp Glu Val Lys Val Trp Pro Gln Gln Pro
1 5 10 15
Ser Gly Glu Leu Phe Glu Ile Glu Ile Asp Thr Leu Glu Thr Thr Cys
20 25 30
His Val Leu Asp Pro Thr Pro Val Ala Arg
35 40
<210> 2251
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2251
His Thr Asn Tyr Thr Met Glu His Ile Arg
1 5 10
<210> 2252
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2252
His Thr Gln Thr Gly Thr Pro Thr Arg
1 5
<210> 2253
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2253
His Thr Ser Leu Gly Pro Leu Glu Ala Lys
1 5 10
<210> 2254
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2254
His Thr Ser Thr Glu His Thr Ser Ser Ser Arg
1 5 10
<210> 2255
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2255
His Thr Ser Val Gln Thr Thr Ser Ser Gly Ser Gly Pro Phe Thr Asp
1 5 10 15
Val Arg
<210> 2256
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2256
His Thr Val Asn Pro Asn Met Lys Glu Asp Gly Ile Leu Gly Pro Ile
1 5 10 15
Ile Arg
<210> 2257
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2257
His Thr Val Ser Gly Gly Ser Leu Leu Met Ala Arg
1 5 10
<210> 2258
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2258
His Val Ala Glu Ala Ile Cys Lys
1 5
<210> 2259
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2259
His Val Glu Asp Val Pro Ala Phe Gln Ala Leu Gly Ser Leu Asn Asp
1 5 10 15
Leu Gln Phe Phe Arg
20
<210> 2260
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2260
His Val Phe Gly Glu Ser Asp Glu Leu Ile Gly Gln Lys
1 5 10
<210> 2261
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2261
His Val Phe Gly Gln Ala Val Lys
1 5
<210> 2262
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2262
His Val Phe Gly Gln Pro Ala Lys
1 5
<210> 2263
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2263
His Val Phe Gly Gln Pro Val Lys
1 5
<210> 2264
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2264
His Val Phe Trp Gly Ser Gly Ser His Thr Leu Pro Ala Leu Leu Glu
1 5 10 15
Asn Leu Lys
<210> 2265
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2265
His Val Ile Gly Leu Gln Met Gly Ser Asn Arg
1 5 10
<210> 2266
<211> 25
<212> PRT
<213> Homo sapiens
<400> 2266
His Val Ile Ile Leu Met Thr Asp Gly Leu His Asn Met Gly Gly Asp
1 5 10 15
Pro Ile Thr Val Ile Asp Glu Ile Arg
20 25
<210> 2267
<211> 32
<212> PRT
<213> Homo sapiens
<400> 2267
His Val Ile Ile Leu Met Thr Asp Gly Leu His Asn Met Gly Gly Asp
1 5 10 15
Pro Ile Thr Val Ile Asp Glu Ile Arg Asp Leu Leu Tyr Ile Gly Lys
20 25 30
<210> 2268
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2268
His Val Leu Ala Ala Trp Ala Leu Gly Ala Lys
1 5 10
<210> 2269
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2269
His Val Leu Ser Val Leu Ser Lys
1 5
<210> 2270
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2270
His Val Leu Thr Leu Thr Asp Gln Val Thr Arg
1 5 10
<210> 2271
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2271
His Val Ser Ser Pro Leu Ala Ser Tyr Phe Leu Ser Phe Pro Tyr Ala
1 5 10 15
Arg
<210> 2272
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2272
His Val Val Leu Ala Gln Leu Trp Ala Gly Leu Arg
1 5 10
<210> 2273
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2273
His Val Val Pro Asn Glu Val Val Val Gln Arg
1 5 10
<210> 2274
<211> 22
<212> PRT
<213> Homo sapiens
<400> 2274
His Val Val Tyr Pro Thr Ala Trp Met Asn Gln Leu Pro Leu Leu Ala
1 5 10 15
Ala Ile Glu Ile Gln Lys
20
<210> 2275
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2275
His Val Tyr Gly Glu Leu Asp Val Gln Ile Gln Arg
1 5 10
<210> 2276
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2276
His Trp Pro Phe Met Val Val Asn Asp Ala Gly Arg Pro Lys
1 5 10
<210> 2277
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2277
His Tyr Asp Gly Ser Tyr Ser Thr Phe Gly Glu Arg
1 5 10
<210> 2278
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2278
His Tyr Glu Gly Ser Thr Val Pro Glu Lys
1 5 10
<210> 2279
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2279
His Tyr Glu Gly Ser Thr Val Pro Glu Lys Lys
1 5 10
<210> 2280
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2280
His Tyr Phe Gln Asn Thr Gln Gly Leu Ile Phe Val Val Asp Ser Asn
1 5 10 15
Asp Arg Glu Arg
20
<210> 2281
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2281
His Tyr Gly Ala Leu Ile Gly Leu Asn Arg
1 5 10
<210> 2282
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2282
His Tyr Gly Gly Leu Thr Gly Leu Asn Lys
1 5 10
<210> 2283
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2283
His Tyr Gly Pro Gly Trp Val Ser Met Ala Asn Ala Gly Lys
1 5 10
<210> 2284
<211> 24
<212> PRT
<213> Homo sapiens
<400> 2284
His Tyr Leu Met Trp Gly Leu Ser Ser Asp Phe Trp Gly Glu Lys Pro
1 5 10 15
Asn Leu Ser Tyr Ile Ile Gly Lys
20
<210> 2285
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2285
His Tyr Gln Ile Asn Gln Gln Trp Glu Arg
1 5 10
<210> 2286
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2286
His Tyr Tyr Glu Ser Glu Val Leu Ala Met Asn Phe Gln Asp Trp Ala
1 5 10 15
Thr Ala Ser Arg
20
<210> 2287
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2287
His Tyr Tyr Ile Ala Ala Glu Glu Ile Ile Trp Asn Tyr Ala Pro Ser
1 5 10 15
Gly Ile Asp Ile Phe Thr Lys
20
<210> 2288
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2288
His Tyr Tyr Ile Gly Ile Ile Glu Thr Thr Trp Asp Tyr Ala Ser Asp
1 5 10 15
His Gly Glu Lys
20
<210> 2289
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2289
His Tyr Tyr Ile Gly Ile Ile Glu Thr Thr Trp Asp Tyr Ala Ser Asp
1 5 10 15
His Gly Glu Lys Lys
20
<210> 2290
<211> 26
<212> PRT
<213> Homo sapiens
<400> 2290
Ile Ala Cys Val Leu Pro Val Leu Met Asp Gly Ile Gln Ser His Pro
1 5 10 15
Gln Lys Pro Phe Tyr Thr Val Gly Glu Lys
20 25
<210> 2291
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2291
Ile Ala Asp Ala His Leu Asp Arg
1 5
<210> 2292
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2292
Ile Ala Glu Phe Thr Thr Asn Leu Thr Glu Glu Glu Glu Lys
1 5 10
<210> 2293
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2293
Ile Ala Glu Leu Ser Ala Thr Ala Gln Glu Ile Ile Lys
1 5 10
<210> 2294
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2294
Ile Ala Phe Ser Ala Thr Arg
1 5
<210> 2295
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2295
Ile Ala Gly Val Asn Ile Lys
1 5
<210> 2296
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2296
Ile Ala His Asp Leu Arg
1 5
<210> 2297
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2297
Ile Ala His Gly His Tyr Lys
1 5
<210> 2298
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2298
Ile Ala Ile Ala Asn Ile Ile Asp Glu Ile Ile Glu Lys
1 5 10
<210> 2299
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2299
Ile Ala Ile Asp Leu Phe Lys
1 5
<210> 2300
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2300
Ile Ala Leu Gly Gly Leu Leu Phe Pro Ala Ser Asn Leu Arg
1 5 10
<210> 2301
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2301
Ile Ala Leu Ser Val His Lys
1 5
<210> 2302
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2302
Ile Ala Met Ala Ala Leu Lys
1 5
<210> 2303
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2303
Ile Ala Asn Lys Lys
1 5
<210> 2304
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2304
Ile Ala Pro Ala Asn Ala Asp Phe Ala Phe Arg
1 5 10
<210> 2305
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2305
Ile Ala Pro Pro Pro Val Val Ser Ser Gly Pro Phe Leu Phe Ile Lys
1 5 10 15
<210> 2306
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2306
Ile Ala Pro Gln Leu Ser Thr Glu Glu Leu Val Ser Leu Gly Glu Lys
1 5 10 15
<210> 2307
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2307
Ile Ala Gln Leu Pro Leu Thr Gly Ser Met Ser Ile Ile Phe Phe Leu
1 5 10 15
Pro Leu Lys
<210> 2308
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2308
Ile Ala Gln Trp Gln Ser Phe Gln Leu Glu Gly Gly Leu Lys
1 5 10
<210> 2309
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2309
Ile Ala Gln Trp Gln Ser Leu Lys
1 5
<210> 2310
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2310
Ile Ala Gln Tyr Tyr Tyr Thr Phe Lys
1 5
<210> 2311
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2311
Ile Ala Arg Pro Lys
1 5
<210> 2312
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2312
Ile Ala Ser Phe Ser Gln Asn Cys Asp Ile Tyr Pro Gly Lys
1 5 10
<210> 2313
<211> 22
<212> PRT
<213> Homo sapiens
<400> 2313
Ile Ala Ser Phe Ser Gln Asn Cys Asp Ile Tyr Pro Gly Lys Asp Phe
1 5 10 15
Val Gln Pro Pro Thr Lys
20
<210> 2314
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2314
Ile Ala Ser Gly Val Ile Ala Pro Lys
1 5
<210> 2315
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2315
Ile Ala Trp His Val Ile Arg
1 5
<210> 2316
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2316
Ile Ala Tyr Cys Glu Lys
1 5
<210> 2317
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2317
Ile Ala Tyr Gly Thr Gln Gly Ser Ser Gly Tyr Ser Leu Arg
1 5 10
<210> 2318
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2318
Ile Cys Ala Met Glu Gly Leu Pro Gln Lys
1 5 10
<210> 2319
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2319
Ile Asp Ala Met Asp Val His Val Lys
1 5
<210> 2320
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2320
Ile Asp Asp Ile Trp Asn Leu Glu Val Lys
1 5 10
<210> 2321
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2321
Ile Asp Asp Ile Trp Asn Leu Glu Val Lys Glu Asn Phe Ala Gly Glu
1 5 10 15
Ala Thr Leu Gln Arg
20
<210> 2322
<211> 24
<212> PRT
<213> Homo sapiens
<400> 2322
Ile Asp Asp Pro Thr Asp Ser Lys Pro Glu Asp Trp Asp Lys Pro Glu
1 5 10 15
His Ile Pro Asp Pro Asp Ala Lys
20
<210> 2323
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2323
Ile Asp Glu Pro Gly Leu Arg
1 5
<210> 2324
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2324
Ile Asp Gly Gln Phe Arg
1 5
<210> 2325
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2325
Ile Asp Ile Ala Gly Arg
1 5
<210> 2326
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2326
Ile Asp Ile Ile Lys
1 5
<210> 2327
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2327
Ile Asp Ile Thr Leu Ser Ser Val Lys
1 5
<210> 2328
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2328
Ile Asp Leu Ala Asp Phe Glu Lys
1 5
<210> 2329
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2329
Ile Asp Asn Val Lys
1 5
<210> 2330
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2330
Ile Asp Asn Val Lys Lys
1 5
<210> 2331
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2331
Ile Asp Gln Leu Glu Gly Asp His Gln Leu Ile Gln Glu Ala Leu Ile
1 5 10 15
Phe Asp Asn Lys
20
<210> 2332
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2332
Ile Asp Gln Leu Glu Lys
1 5
<210> 2333
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2333
Ile Asp Gln Asn Val Glu Glu Leu Lys
1 5
<210> 2334
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2334
Ile Asp Gln Asn Val Glu Glu Leu Lys Gly Arg
1 5 10
<210> 2335
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2335
Ile Asp Gln Thr Val Glu Glu Leu Arg
1 5
<210> 2336
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2336
Ile Asp Gln Thr Val Glu Glu Leu Arg Arg
1 5 10
<210> 2337
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2337
Ile Asp Arg Phe Met Gln Ala Val Thr Gly Trp Lys
1 5 10
<210> 2338
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2338
Ile Asp Arg Pro Glu Ala Ser Arg
1 5
<210> 2339
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2339
Ile Asp Ser Glu Ile Lys
1 5
<210> 2340
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2340
Ile Asp Ser Leu Leu Glu Asn Asp Arg
1 5
<210> 2341
<211> 24
<212> PRT
<213> Homo sapiens
<400> 2341
Ile Asp Ser Leu Leu Glu Asn Asp Arg Gln Gln Thr His Met Leu Asp
1 5 10 15
Val Met Gln Asp His Phe Ser Arg
20
<210> 2342
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2342
Ile Asp Thr Ala Leu Ile Lys
1 5
<210> 2343
<211> 35
<212> PRT
<213> Homo sapiens
<400> 2343
Ile Asp Thr Ile Asn Leu Phe Pro Ala Thr Leu Phe Asp Ala Tyr Met
1 5 10 15
Val Ala Gln Asn Pro Gly Glu Trp Met Leu Ser Cys Gln Asn Leu Asn
20 25 30
His Leu Lys
35
<210> 2344
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2344
Ile Asp Thr Gln Asp Ile Glu Ala Ser His Tyr Arg
1 5 10
<210> 2345
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2345
Ile Asp Val His Leu Val Pro Asp Arg
1 5
<210> 2346
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2346
Ile Asp Val His Leu Val Pro Asp Arg Lys
1 5 10
<210> 2347
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2347
Ile Asp Val His Trp Thr Arg
1 5
<210> 2348
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2348
Ile Glu Ala Ile Lys
1 5
<210> 2349
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2349
Ile Glu Ala Leu Lys
1 5
<210> 2350
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2350
Ile Glu Asp Gly Phe Ser Leu Lys
1 5
<210> 2351
<211> 24
<212> PRT
<213> Homo sapiens
<400> 2351
Ile Glu Asp Gly Phe Ser Leu Lys Glu Gln Leu Gln Asp Met Gly Leu
1 5 10 15
Val Asp Leu Phe Ser Pro Glu Lys
20
<210> 2352
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2352
Ile Glu Asp Gly Thr Leu Ala Ser Lys
1 5
<210> 2353
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2353
Ile Glu Asp Gly Val Pro Gln His Leu Val Leu Val Leu Gly Gly Lys
1 5 10 15
<210> 2354
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2354
Ile Glu Asp Leu Pro Thr Met Val Thr Leu Gly Asn Ser Phe Leu His
1 5 10 15
Lys
<210> 2355
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2355
Ile Glu Glu Ala Asp Cys Lys
1 5
<210> 2356
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2356
Ile Glu Glu Ala Gln Lys
1 5
<210> 2357
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2357
Ile Glu Glu Gly Val Pro Gln Phe Leu Val Leu Ile Ser Ser Gly Lys
1 5 10 15
<210> 2358
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2358
Ile Glu Glu Ile Ala Ala Lys
1 5
<210> 2359
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2359
Ile Glu Phe Ile Ser Thr Met Glu Gly Tyr Lys
1 5 10
<210> 2360
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2360
Ile Glu Gly Asp Glu Glu Met His Cys Ser Asp Asp Gly Phe Trp Ser
1 5 10 15
Lys
<210> 2361
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2361
Ile Glu Gly Asn Leu Ile Phe Asp Pro Asn Asn Tyr Leu Pro Lys
1 5 10 15
<210> 2362
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2362
Ile Glu Ile Pro Leu Pro Phe Gly Gly Lys
1 5 10
<210> 2363
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2363
Ile Glu Ile Ser Glu Leu Asn Arg
1 5
<210> 2364
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2364
Ile Glu Lys Val Glu His Ser Asp Leu Ser Phe Ser Lys
1 5 10
<210> 2365
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2365
Ile Glu Met Ser Lys
1 5
<210> 2366
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2366
Ile Glu Asn Phe Arg
1 5
<210> 2367
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2367
Ile Glu Asn Val Ser Tyr Gln Asp Lys
1 5
<210> 2368
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2368
Ile Glu Pro Ser Gln Ala Lys
1 5
<210> 2369
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2369
Ile Glu Arg Glu Ile Lys
1 5
<210> 2370
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2370
Ile Glu Ser Leu Thr Arg
1 5
<210> 2371
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2371
Ile Glu Ser Pro Gly Tyr Leu Thr Ser Pro Gly Tyr Pro His Ser Tyr
1 5 10 15
His Pro Ser Glu Lys
20
<210> 2372
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2372
Ile Glu Thr Ile Ser His Glu Asp Leu Gln Arg
1 5 10
<210> 2373
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2373
Ile Glu Val Glu Lys Pro Phe Ala Ile Ala Lys Glu
1 5 10
<210> 2374
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2374
Ile Glu Val Gly Arg Phe Pro Val Leu Glu Gly Gln Arg
1 5 10
<210> 2375
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2375
Ile Glu Val Ile Lys
1 5
<210> 2376
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2376
Ile Glu Val Leu Lys
1 5
<210> 2377
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2377
Ile Glu Val Leu Lys Arg
1 5
<210> 2378
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2378
Ile Glu Val Asn Val Glu Leu Arg Lys
1 5
<210> 2379
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2379
Ile Glu Val Gln Leu Lys
1 5
<210> 2380
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2380
Ile Glu Val Gln Leu Lys Asn Glu His Thr Ser Lys
1 5 10
<210> 2381
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2381
Ile Glu Trp Leu Glu Ser His Gln Asp Ala Asp Ile Glu Asp Phe Lys
1 5 10 15
<210> 2382
<211> 31
<212> PRT
<213> Homo sapiens
<400> 2382
Ile Phe Asp Asp Phe Gly Thr His Tyr Phe Thr Ser Gly Ser Leu Gly
1 5 10 15
Gly Val Tyr Asp Leu Leu Tyr Gln Phe Ser Ser Glu Glu Leu Lys
20 25 30
<210> 2383
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2383
Ile Phe Asp Gly Lys
1 5
<210> 2384
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2384
Ile Phe Glu Gly Asn Thr Asn Thr Lys
1 5
<210> 2385
<211> 25
<212> PRT
<213> Homo sapiens
<400> 2385
Ile Phe Glu Leu Phe Glu Val Gly Phe Leu Ser Pro Ala Thr Phe Thr
1 5 10 15
Val Tyr Glu Tyr His Arg Pro Asp Lys
20 25
<210> 2386
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2386
Ile Phe Phe His Leu Asn Ala Val Ala Leu Gly Asp Gly Gly His Tyr
1 5 10 15
Thr Cys Arg
<210> 2387
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2387
Ile Phe Phe Pro Gly Val Ser Glu Phe Gly Lys
1 5 10
<210> 2388
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2388
Ile Phe Gly Phe Met Glu Glu Glu Arg Lys
1 5 10
<210> 2389
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2389
Ile Phe Gly Asn Lys
1 5
<210> 2390
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2390
Ile Phe His Gly Leu Lys
1 5
<210> 2391
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2391
Ile Phe His Val Asn Trp Phe Arg
1 5
<210> 2392
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2392
Ile Phe Ile Leu Gly Pro Ser His His Val Pro Leu Ser Arg
1 5 10
<210> 2393
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2393
Ile Phe Leu Tyr Lys
1 5
<210> 2394
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2394
Ile Phe Asn Gly Arg Pro Ala Gln Lys
1 5
<210> 2395
<211> 52
<212> PRT
<213> Homo sapiens
<400> 2395
Ile Phe Gln His Ala Val Val Ile His Ser Asp Tyr Ala Ile Ser Val
1 5 10 15
Gln Ala Leu Asn Ala Lys Pro Asp Thr Ala Glu Leu Thr Leu Leu Arg
20 25 30
Pro Ile Gln Ala Leu Gly Thr Glu Tyr Phe Val Leu Thr Pro Pro Gly
35 40 45
Thr Ser Ala Arg
50
<210> 2396
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2396
Ile Phe Arg Asp Gly Glu Glu Ala Gly Ala Tyr Asp Gly Pro Arg
1 5 10 15
<210> 2397
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2397
Ile Phe Ser Val Lys
1 5
<210> 2398
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2398
Ile Phe Thr Lys Val Gln Thr Ala His Phe Lys
1 5 10
<210> 2399
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2399
Ile Phe Thr Asn Phe His Arg
1 5
<210> 2400
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2400
Ile Phe Thr Asn Thr Lys
1 5
<210> 2401
<211> 24
<212> PRT
<213> Homo sapiens
<400> 2401
Ile Phe Thr Pro Leu Leu His Gln Ile Glu Leu Glu Lys Pro Lys Pro
1 5 10 15
Ile Pro Tyr Ile Tyr Gly Ser Arg
20
<210> 2402
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2402
Ile Phe Thr Val Asn His Lys
1 5
<210> 2403
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2403
Ile Phe Thr Val Asn His Lys Leu Leu Pro Val Gly Arg
1 5 10
<210> 2404
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2404
Ile Phe Val Thr Thr Lys
1 5
<210> 2405
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2405
Ile Phe Val Trp Lys
1 5
<210> 2406
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2406
Ile Phe Trp Gly Gly Lys
1 5
<210> 2407
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2407
Ile Phe Tyr Ile Lys
1 5
<210> 2408
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2408
Ile Phe Tyr Leu Lys
1 5
<210> 2409
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2409
Ile Phe Tyr Asn Gln Gln Asn His Tyr Asp Gly Ser Thr Gly Lys
1 5 10 15
<210> 2410
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2410
Ile Gly Ala Glu Val Tyr His Asn Leu Lys
1 5 10
<210> 2411
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2411
Ile Gly Ala Ile Lys
1 5
<210> 2412
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2412
Ile Gly Asp Leu His Pro Gln Ile Val Asn Leu Leu Lys
1 5 10
<210> 2413
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2413
Ile Gly Asp Asn Leu Arg
1 5
<210> 2414
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2414
Ile Gly Asp Gln Trp Asp Lys
1 5
<210> 2415
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2415
Ile Gly Asp Thr Trp Arg
1 5
<210> 2416
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2416
Ile Gly Asp Thr Trp Ser Lys
1 5
<210> 2417
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2417
Ile Gly Asp Thr Trp Ser Lys Lys
1 5
<210> 2418
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2418
Ile Gly Glu His Thr Pro Ser Ala Leu Ala Ile Met Glu Asn Ala Asn
1 5 10 15
Val Leu Ala Arg
20
<210> 2419
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2419
Ile Gly Glu Ile Lys Glu Glu Thr Thr Ser His Leu Arg
1 5 10
<210> 2420
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2420
Ile Gly Glu Ser Ile Glu Leu Thr Cys Pro Lys
1 5 10
<210> 2421
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2421
Ile Gly Phe Lys Leu Gly Val Arg Pro Ser Gln Gly Gly Glu Ala Pro
1 5 10 15
Arg
<210> 2422
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2422
Ile Gly Phe Pro Trp Ser Glu Ile Arg
1 5
<210> 2423
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2423
Ile Gly Gly Ala Ile Glu Glu Val Tyr Val Ser Leu Gly Val Ser Val
1 5 10 15
Gly Lys
<210> 2424
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2424
Ile Gly Gly Ser Tyr Lys
1 5
<210> 2425
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2425
Ile Gly Gly Ser Tyr Lys Lys
1 5
<210> 2426
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2426
Ile Gly Gly Tyr Lys
1 5
<210> 2427
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2427
Ile Gly His Leu Met Leu Lys Pro Leu Lys
1 5 10
<210> 2428
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2428
Ile Gly Ile Thr Asn His Asp Glu Tyr Ser Leu Val Arg
1 5 10
<210> 2429
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2429
Ile Gly Lys Pro Ala Pro Asp Phe Lys
1 5
<210> 2430
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2430
Ile Gly Asn Phe Ser Thr Asp Ile Lys
1 5
<210> 2431
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2431
Ile Gly Gln Asp Gly Ile Ser Thr Ser Ala Thr Thr Asn Leu Lys
1 5 10 15
<210> 2432
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2432
Ile Gly Val Glu Leu Thr Gly Arg
1 5
<210> 2433
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2433
Ile Gly Val His Ala Phe Gln Gln Arg
1 5
<210> 2434
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2434
Ile Gly Tyr Pro Lys Pro Ala Leu Leu His Ser Thr Phe Phe Pro Ala
1 5 10 15
Leu Gln Gly Ala Gln Thr Lys
20
<210> 2435
<211> 44
<212> PRT
<213> Homo sapiens
<400> 2435
Ile His Glu Asp Ser Asp Ser Ala Leu Gln Leu Gln Asp Phe Tyr Gln
1 5 10 15
Glu Val Ala Asn Pro Leu Leu Thr Ala Val Thr Phe Glu Tyr Pro Ser
20 25 30
Asn Ala Val Glu Glu Val Thr Gln Asn Asn Phe Arg
35 40
<210> 2436
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2436
Ile His Phe Ile Ala Pro Lys
1 5
<210> 2437
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2437
Ile His Phe Pro Leu Ala Thr Tyr Ala Pro Val Ile Ser Ala Glu Lys
1 5 10 15
<210> 2438
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2438
Ile His Gly Ile Leu Ser Asn Thr His Arg
1 5 10
<210> 2439
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2439
Ile His Ile Gly Ser Ser Phe Glu Lys
1 5
<210> 2440
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2440
Ile His Ile Gly Ser Ser Phe Glu Lys Tyr Pro Leu Tyr Val Leu Lys
1 5 10 15
<210> 2441
<211> 29
<212> PRT
<213> Homo sapiens
<400> 2441
Ile His Ile Leu Pro Ser Met Asn Pro Asp Gly Tyr Glu Val Ala Ala
1 5 10 15
Ala Gln Gly Pro Asn Lys Pro Gly Tyr Leu Val Gly Arg
20 25
<210> 2442
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2442
Ile His Leu Gly Ser Ser Pro Lys
1 5
<210> 2443
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2443
Ile His Leu Ile Ser Thr Gln Ser Ala Ile Pro Tyr Ala Leu Arg
1 5 10 15
<210> 2444
<211> 24
<212> PRT
<213> Homo sapiens
<400> 2444
Ile His Leu Ile Ser Thr Gln Ser Ala Ile Pro Tyr Ala Leu Arg Val
1 5 10 15
Glu Leu Glu Asp Trp Asn Gly Arg
20
<210> 2445
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2445
Ile His Leu Met Ala Gly Arg
1 5
<210> 2446
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2446
Ile His Pro Phe Phe Lys
1 5
<210> 2447
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2447
Ile His Pro Leu Leu Lys
1 5
<210> 2448
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2448
Ile His Pro Thr Ser Val Ile Ser Gly Tyr Arg
1 5 10
<210> 2449
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2449
Ile His Pro Val Ser Thr Met Val Lys
1 5
<210> 2450
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2450
Ile His Ser Asp Leu Ala Glu Glu Arg
1 5
<210> 2451
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2451
Ile His Ser Gly Ser Phe Gln Ser Gln Val Glu Leu Ser Asn Asp Gln
1 5 10 15
Glu Lys
<210> 2452
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2452
Ile His Val Tyr Glu Lys
1 5
<210> 2453
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2453
Ile His Trp Glu Ser Ala Ser Leu Leu Arg
1 5 10
<210> 2454
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2454
Ile Ile Ala Pro Pro Glu Arg
1 5
<210> 2455
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2455
Ile Ile Ala Pro Pro Glu Arg Lys
1 5
<210> 2456
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2456
Ile Ile Ala Gln Lys
1 5
<210> 2457
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2457
Ile Ile Asp Glu Leu Asn Val Lys Pro Glu Gly Thr Arg
1 5 10
<210> 2458
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2458
Ile Ile Glu Gly Glu Pro Asn Leu Lys
1 5
<210> 2459
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2459
Ile Ile Phe Gly Tyr Lys
1 5
<210> 2460
<211> 22
<212> PRT
<213> Homo sapiens
<400> 2460
Ile Ile Phe His Glu Asn Tyr Asn Ala Gly Thr Tyr Gln Asn Asp Ile
1 5 10 15
Ala Leu Ile Glu Met Lys
20
<210> 2461
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2461
Ile Ile Phe His Glu Asn Tyr Asn Ala Gly Thr Tyr Gln Asn Asp Ile
1 5 10 15
Ala Leu Ile Glu Met Lys Lys
20
<210> 2462
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2462
Ile Ile Gly Gly Gln Lys
1 5
<210> 2463
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2463
Ile Ile Gly Gly Ser Asp Ala Asp Ile Lys
1 5 10
<210> 2464
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2464
Ile Ile Gly His Met Leu Lys
1 5
<210> 2465
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2465
Ile Ile His Phe Gly Thr Arg
1 5
<210> 2466
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2466
Ile Ile His Gly Asn Gln Ile Ala Thr Asn Gly Val Val His Val Ile
1 5 10 15
Asp Arg
<210> 2467
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2467
Ile Ile Ile Ile Lys
1 5
<210> 2468
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2468
Ile Ile Ile Leu Lys
1 5
<210> 2469
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2469
Ile Ile Ile Leu Arg
1 5
<210> 2470
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2470
Ile Ile Ile Asn Val Gly Gly Ile Lys
1 5
<210> 2471
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2471
Ile Ile Ile Pro Pro Arg
1 5
<210> 2472
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2472
Ile Ile Lys Glu Thr Gln Arg
1 5
<210> 2473
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2473
Ile Ile Leu Phe Ser Asn Gln Phe Arg
1 5
<210> 2474
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2474
Ile Ile Leu Phe Thr Glu Asp Pro Arg
1 5
<210> 2475
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2475
Ile Ile Leu Leu Phe Asp Ala His Lys
1 5
<210> 2476
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2476
Ile Ile Leu Thr Ala Arg Pro Phe Arg
1 5
<210> 2477
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2477
Ile Ile Leu Tyr Lys
1 5
<210> 2478
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2478
Ile Ile Asn Glu Pro Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Lys
1 5 10 15
<210> 2479
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2479
Ile Ile Asn Glu Pro Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Lys
1 5 10 15
Arg
<210> 2480
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2480
Ile Ile Asn Glu Val Ser Lys Pro Leu Ala His His Ile Pro Val Glu
1 5 10 15
Lys
<210> 2481
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2481
Ile Ile Pro Phe Asn Arg
1 5
<210> 2482
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2482
Ile Ile Pro Phe Asn Arg Leu Thr Ile Gly Glu Gly Gln Gln His His
1 5 10 15
Leu Gly Gly Ala Lys
20
<210> 2483
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2483
Ile Ile Pro His His Asn Tyr Asn Ala Ala Ile Asn Lys
1 5 10
<210> 2484
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2484
Ile Ile Arg Ala Ser Arg
1 5
<210> 2485
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2485
Ile Ile Ser Asp Tyr His Gln Gln Phe Arg
1 5 10
<210> 2486
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2486
Ile Ile Ser Ile Met Asp Glu Lys
1 5
<210> 2487
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2487
Ile Ile Thr Ile Thr Lys
1 5
<210> 2488
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2488
Ile Ile Val Pro Leu Asn Asn Arg
1 5
<210> 2489
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2489
Ile Ile Tyr Lys Glu Asn Glu Arg
1 5
<210> 2490
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2490
Ile Lys Glu Asp Glu Asp Asp Lys
1 5
<210> 2491
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2491
Ile Lys Phe Glu Met Glu Gln Asn Leu Arg
1 5 10
<210> 2492
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2492
Ile Lys Gly Val Ile Ser Ile Pro Arg
1 5
<210> 2493
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2493
Ile Lys Leu Pro Ala Lys
1 5
<210> 2494
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2494
Ile Lys Pro Ala Val Ile Lys
1 5
<210> 2495
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2495
Ile Lys Pro Leu Lys
1 5
<210> 2496
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2496
Ile Lys Pro Ser Phe Asn Ile Val Pro Leu Thr Ser Arg
1 5 10
<210> 2497
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2497
Ile Lys Pro Val Phe Ile Glu Asp Ala Asn Phe Gly Arg
1 5 10
<210> 2498
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2498
Ile Lys Gln Ser Glu Leu Ser Ala Lys
1 5
<210> 2499
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2499
Ile Lys Ser Leu Leu Pro Lys
1 5
<210> 2500
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2500
Ile Lys Ser Ser Phe Val Ala Pro Leu Glu Lys
1 5 10
<210> 2501
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2501
Ile Lys Thr Asp Gly Ala Ala Pro Asn Val Ala Pro Ser Asp Val Gly
1 5 10 15
Gly Gly Gly Gly Arg
20
<210> 2502
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2502
Ile Lys Val Thr Thr Ser Gln Asp Met Leu Ser Ile Met Glu Lys
1 5 10 15
<210> 2503
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2503
Ile Leu Ala Gly Pro Ala Gly Asp Ser Asn Val Val Lys
1 5 10
<210> 2504
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2504
Ile Leu Ala Asn Gly Leu Leu Gln Leu Gly His Gly Leu Lys
1 5 10
<210> 2505
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2505
Ile Leu Ala Gln Ala Thr Ser Asp Leu Val Asn Ala Ile Lys
1 5 10
<210> 2506
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2506
Ile Leu Asp Asp Leu Ser Pro Arg
1 5
<210> 2507
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2507
Ile Leu Asp Glu Ile Glu Glu His Asn Ile Lys
1 5 10
<210> 2508
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2508
Ile Leu Glu Ala His Gln Asn Val Ala Gln Leu Ser Leu Ala Glu Ala
1 5 10 15
Gln Leu Arg
<210> 2509
<211> 24
<212> PRT
<213> Homo sapiens
<400> 2509
Ile Leu Glu Asp Met Gln Glu Glu Asp Tyr Leu Asn Phe Ile Leu Phe
1 5 10 15
Ser Gly Asp Val Ser Thr Trp Lys
20
<210> 2510
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2510
Ile Leu Glu Glu Asn Lys Glu Leu Glu Asn Ala Leu Lys
1 5 10
<210> 2511
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2511
Ile Leu Glu Gly Phe Gln Pro Ser Gly Arg
1 5 10
<210> 2512
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2512
Ile Leu Phe Ile Phe Ile Asp Ser Asp His Thr Asp Asn Gln Arg
1 5 10 15
<210> 2513
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2513
Ile Leu Phe Asn Lys Lys
1 5
<210> 2514
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2514
Ile Leu Phe Ser Ser Arg
1 5
<210> 2515
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2515
Ile Leu Gly Ala Val Ala Lys
1 5
<210> 2516
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2516
Ile Leu Gly Ala Val Ala Lys Val Arg
1 5
<210> 2517
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2517
Ile Leu Gly Asp Met Gln Pro Gly Asp Tyr Phe Asp Leu Val Leu Phe
1 5 10 15
Gly Thr Arg
<210> 2518
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2518
Ile Leu Gly Asp Pro Glu Ala Leu Arg Asp Leu Leu Asn Asn His Ile
1 5 10 15
Leu Lys
<210> 2519
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2519
Ile Leu Gly Glu Glu Leu Gly Phe Ala Ser Leu His Asp Leu Gln Leu
1 5 10 15
Leu Gly Lys
<210> 2520
<211> 26
<212> PRT
<213> Homo sapiens
<400> 2520
Ile Leu Gly Glu Glu Leu Gly Phe Ala Ser Leu His Asp Leu Gln Leu
1 5 10 15
Leu Gly Lys Leu Leu Leu Met Gly Ala Arg
20 25
<210> 2521
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2521
Ile Leu Gly Gly His Leu Asp Ala Lys
1 5
<210> 2522
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2522
Ile Leu Gly Gly Ser Gln Val Glu Lys
1 5
<210> 2523
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2523
Ile Leu Gly Gly Ser Val Leu His Leu Val Leu Ala Leu Arg
1 5 10
<210> 2524
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2524
Ile Leu Gly Pro Leu Ser Tyr Ser Lys
1 5
<210> 2525
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2525
Ile Leu Gly Val Pro Arg
1 5
<210> 2526
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2526
Ile Leu His Leu Pro Thr Ser Trp Asp Trp Arg
1 5 10
<210> 2527
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2527
Ile Leu Ile Gly Thr Val Phe His Lys
1 5
<210> 2528
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2528
Ile Leu Ile Leu Arg
1 5
<210> 2529
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2529
Ile Leu Ile Asn Leu Met Lys
1 5
<210> 2530
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2530
Ile Leu Leu Phe Lys
1 5
<210> 2531
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2531
Ile Leu Leu Phe Arg
1 5
<210> 2532
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2532
Ile Leu Leu Gly Gly Tyr Gln Ser Arg
1 5
<210> 2533
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2533
Ile Leu Leu Ile Lys
1 5
<210> 2534
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2534
Ile Leu Leu Leu Lys
1 5
<210> 2535
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2535
Ile Leu Leu Leu Arg
1 5
<210> 2536
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2536
Ile Leu Leu Asn Ile Glu His Arg
1 5
<210> 2537
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2537
Ile Leu Leu Asn Pro Gln Ser His Lys
1 5
<210> 2538
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2538
Ile Leu Leu Thr Pro Arg
1 5
<210> 2539
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2539
Ile Leu Leu Val Ala Lys
1 5
<210> 2540
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2540
Ile Leu Leu Val Ala Lys Arg
1 5
<210> 2541
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2541
Ile Leu Leu Tyr Arg
1 5
<210> 2542
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2542
Ile Leu Leu Tyr Thr Met Asn Pro Asn Lys Phe Arg
1 5 10
<210> 2543
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2543
Ile Leu Asn Asn Gly His Ala Phe Asn Val Glu Phe Asp Asp Ser Gln
1 5 10 15
Asp Lys
<210> 2544
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2544
Ile Leu Asn Pro Leu Arg
1 5
<210> 2545
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2545
Ile Leu Pro Leu Thr Val Cys Lys
1 5
<210> 2546
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2546
Ile Leu Gln Leu Lys
1 5
<210> 2547
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2547
Ile Leu Ser Gly Asp Pro Tyr Cys Glu Lys
1 5 10
<210> 2548
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2548
Ile Leu Ser Gly Arg Pro Pro Leu Gly Phe Leu Asn Pro Arg
1 5 10
<210> 2549
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2549
Ile Leu Ser Leu Arg
1 5
<210> 2550
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2550
Ile Leu Ser Val Lys
1 5
<210> 2551
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2551
Ile Leu Thr Leu Pro Arg
1 5
<210> 2552
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2552
Ile Leu Thr Gln Arg
1 5
<210> 2553
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2553
Ile Leu Thr Ser Lys
1 5
<210> 2554
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2554
Ile Leu Thr Thr Gly Phe Ser Arg
1 5
<210> 2555
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2555
Ile Leu Val Gly Asn Lys
1 5
<210> 2556
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2556
Ile Leu Val Gly Arg
1 5
<210> 2557
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2557
Ile Leu Val Ile Asn Lys
1 5
<210> 2558
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2558
Ile Leu Trp Ser Arg
1 5
<210> 2559
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2559
Ile Met Ala Asp Ser Gly Pro Ile Tyr Asp Lys
1 5 10
<210> 2560
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2560
Ile Met Ala Leu Glu Lys
1 5
<210> 2561
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2561
Ile Met Gly Ile Thr Leu Val Ser Lys
1 5
<210> 2562
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2562
Ile Met Gly Ile Thr Leu Val Ser Lys Lys
1 5 10
<210> 2563
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2563
Ile Met Gly Pro Asn Tyr Thr Pro Gly Lys Lys
1 5 10
<210> 2564
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2564
Ile Met Asn Met Ile Lys
1 5
<210> 2565
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2565
Ile Met Gln Ser Ser Gln Ser Met Ser Lys
1 5 10
<210> 2566
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2566
Ile Met Tyr Thr Val Phe Glu His Thr Phe His Val Arg
1 5 10
<210> 2567
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2567
Ile Asn Ala Ala Lys
1 5
<210> 2568
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2568
Ile Asn Cys Gln Gly Lys
1 5
<210> 2569
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2569
Ile Asn Cys Gln Gly Lys Thr Tyr Leu Phe Lys
1 5 10
<210> 2570
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2570
Ile Asn Asp Val Leu Glu His Val Lys
1 5
<210> 2571
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2571
Ile Asn Glu Ile Arg
1 5
<210> 2572
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2572
Ile Asn Glu Leu Leu Lys
1 5
<210> 2573
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2573
Ile Asn Glu Asn Thr Gly Ser Val Ser Val Thr Arg
1 5 10
<210> 2574
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2574
Ile Asn Glu Val Lys
1 5
<210> 2575
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2575
Ile Asn Phe Asn Glu Lys
1 5
<210> 2576
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2576
Ile Asn His Gly Ile Leu Tyr Asp Glu Glu Lys
1 5 10
<210> 2577
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2577
Ile Asn Asn Gln Leu Thr Leu Asp Ser Asn Thr Lys
1 5 10
<210> 2578
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2578
Ile Asn Asn Gln Leu Thr Leu Asp Ser Asn Thr Lys Tyr Phe His Lys
1 5 10 15
<210> 2579
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2579
Ile Asn Pro Leu Ala Leu Lys
1 5
<210> 2580
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2580
Ile Asn Thr Glu Glu Lys
1 5
<210> 2581
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2581
Ile Asn Thr Ser Arg
1 5
<210> 2582
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2582
Ile Asn Val Gly Gly Gly Leu Ser Gly Asp His Cys Lys
1 5 10
<210> 2583
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2583
Ile Asn Val Gly Gly Gly Leu Ser Gly Asp His Cys Lys Lys
1 5 10
<210> 2584
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2584
Ile Asn Val Lys Val Gly Gly Asn Ser Lys
1 5 10
<210> 2585
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2585
Ile Asn Val Leu Gln Lys
1 5
<210> 2586
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2586
Ile Pro Glu Ala Pro Ala Gly Pro Pro Ser Asp Phe Gly Leu Phe Leu
1 5 10 15
Ser Asp Asp Asp Pro Lys Lys
20
<210> 2587
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2587
Ile Pro Glu Ala Arg
1 5
<210> 2588
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2588
Ile Pro Glu Ala Ser Pro Lys
1 5
<210> 2589
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2589
Ile Pro Glu Ala Thr Asn Arg
1 5
<210> 2590
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2590
Ile Pro Glu Ala Thr Asn Arg Arg
1 5
<210> 2591
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2591
Ile Pro Gly Ile Phe Glu Leu Gly Ile Ser Ser Gln Ser Asp Arg
1 5 10 15
<210> 2592
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2592
Ile Pro Gly Ile Phe Glu Leu Gly Ile Ser Ser Gln Ser Asp Arg Gly
1 5 10 15
Lys
<210> 2593
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2593
Ile Pro Lys Pro Glu Ala Ser Phe Ser Pro Arg
1 5 10
<210> 2594
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2594
Ile Pro Leu Asp Leu Val Pro Lys
1 5
<210> 2595
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2595
Ile Pro Leu Asn Asp Leu Phe Arg
1 5
<210> 2596
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2596
Ile Pro Leu Pro Arg
1 5
<210> 2597
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2597
Ile Pro Leu Gln Pro Lys
1 5
<210> 2598
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2598
Ile Pro Leu Ser Pro Val His Lys
1 5
<210> 2599
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2599
Ile Pro Leu Ser Arg
1 5
<210> 2600
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2600
Ile Pro Met Phe Ile Val His Lys
1 5
<210> 2601
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2601
Ile Pro Asn Glu Gly His Ile Ser His Phe Gln Gly Lys
1 5 10
<210> 2602
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2602
Ile Pro Pro Leu Arg
1 5
<210> 2603
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2603
Ile Pro Ser Asn Pro Arg
1 5
<210> 2604
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2604
Ile Pro Ser Asn Pro Ser His Arg
1 5
<210> 2605
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2605
Ile Pro Ser Val Gln Ile Asn Phe Lys
1 5
<210> 2606
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2606
Ile Pro Thr Ile Ser Thr Gln Leu Lys
1 5
<210> 2607
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2607
Ile Pro Val Asp Glu Glu Ala Phe Val Ile Asp Phe Lys Pro Arg
1 5 10 15
<210> 2608
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2608
Ile Pro Val His Pro Asn Asp His Val Asn Lys
1 5 10
<210> 2609
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2609
Ile Pro Val Lys Lys
1 5
<210> 2610
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2610
Ile Pro Val Pro Val Ala Lys
1 5
<210> 2611
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2611
Ile Pro Tyr Ser Phe Phe Lys
1 5
<210> 2612
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2612
Ile Pro Tyr Tyr Asn Ile His Pro Met Pro Val His Leu Gln Gln Arg
1 5 10 15
<210> 2613
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2613
Ile Gln Ala Glu Glu Gly Asp Lys
1 5
<210> 2614
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2614
Ile Gln Ala Leu Ser Leu Cys Ser Asp Gln Gln Ser His Leu Glu Phe
1 5 10 15
Arg
<210> 2615
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2615
Ile Gln Asp Lys Leu Asn Lys
1 5
<210> 2616
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2616
Ile Gln Glu Ala Trp Lys
1 5
<210> 2617
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2617
Ile Gln Glu Asn Thr Phe Lys
1 5
<210> 2618
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2618
Ile Gln Glu Asn Val Arg
1 5
<210> 2619
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2619
Ile Gln Glu Asn Val Arg Asn Ala Ile Gly Gly Lys
1 5 10
<210> 2620
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2620
Ile Gln Glu Val Ala Asp Glu Leu Gln Lys
1 5 10
<210> 2621
<211> 22
<212> PRT
<213> Homo sapiens
<400> 2621
Ile Gln Gly Gln Glu Leu Ser Ala Tyr Gln Ala Pro Ser Pro Pro Ala
1 5 10 15
His Ser Gly Phe His Arg
20
<210> 2622
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2622
Ile Gln His Pro Phe Thr Val Glu Glu Phe Val Leu Pro Lys
1 5 10
<210> 2623
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2623
Ile Gln His Thr Val Thr Ala Ser Val Arg
1 5 10
<210> 2624
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2624
Ile Gln Ile Gly Ile Tyr Val Glu Ile Lys
1 5 10
<210> 2625
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2625
Ile Gln Ile Gln Glu Lys
1 5
<210> 2626
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2626
Ile Gln Lys Leu Glu Ser Asp Val Ser Ala Gln Met Glu Tyr Cys Arg
1 5 10 15
<210> 2627
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2627
Ile Gln Leu Val Glu Glu Glu Leu Asp Arg
1 5 10
<210> 2628
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2628
Ile Gln Leu Val Glu Glu Glu Leu Asp Arg Ala Gln Glu Arg
1 5 10
<210> 2629
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2629
Ile Gln Asn Ile Leu Thr Glu Glu Pro Lys
1 5 10
<210> 2630
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2630
Ile Gln Asn Gln Phe Asn Leu Lys
1 5
<210> 2631
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2631
Ile Gln Asn Thr Leu Gln Lys
1 5
<210> 2632
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2632
Ile Gln Pro Ser Gly Gly Thr Asn Ile Asn Glu Ala Leu Leu Arg
1 5 10 15
<210> 2633
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2633
Ile Gln Gln Arg Gln Leu Leu Ile Ser His Gln Arg
1 5 10
<210> 2634
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2634
Ile Gln Ser Ser His Asn Phe Gln Leu Glu Ser Val Asn Lys
1 5 10
<210> 2635
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2635
Ile Gln Thr His Ser Thr Thr Tyr Arg
1 5
<210> 2636
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2636
Ile Gln Val Tyr Ser Arg
1 5
<210> 2637
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2637
Ile Gln Tyr Gln Leu Val Asp Ile Ser Gln Asp Asn Ala Leu Arg Asp
1 5 10 15
Glu Met Arg
<210> 2638
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2638
Ile Gln Tyr Tyr Cys His Glu Pro Tyr Tyr Lys
1 5 10
<210> 2639
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2639
Ile Arg Glu Glu Gly Thr Asp Leu Glu Val Thr Ala Asn Arg
1 5 10
<210> 2640
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2640
Ile Arg Glu Glu Tyr Pro Asp Arg
1 5
<210> 2641
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2641
Ile Arg Leu Glu Pro Gly Lys
1 5
<210> 2642
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2642
Ile Arg Pro Ala Val Gly Trp Gly Arg
1 5
<210> 2643
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2643
Ile Arg Pro Phe Phe Pro Gln Gln
1 5
<210> 2644
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2644
Ile Arg Pro His Thr Phe Thr Gly Leu Ser Gly Leu Arg
1 5 10
<210> 2645
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2645
Ile Arg Pro Leu Val Thr Gln
1 5
<210> 2646
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2646
Ile Arg Pro Leu Trp Lys
1 5
<210> 2647
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2647
Ile Arg Pro Asn Asp Phe Ile Pro Asn Val Ile
1 5 10
<210> 2648
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2648
Ile Ser Ala Asp Lys Lys
1 5
<210> 2649
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2649
Ile Ser Ala Ser Ala Glu Glu Leu Arg
1 5
<210> 2650
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2650
Ile Ser Ala Ser Ser Glu Val Ala Phe Leu Ser Ile Gln Ile Lys
1 5 10 15
<210> 2651
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2651
Ile Ser Ala Val Ser Leu Ala Asn Arg
1 5
<210> 2652
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2652
Ile Ser Ala Val Ser Val Ala Glu Arg
1 5
<210> 2653
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2653
Ile Ser Cys Thr Ile Ala Asn Arg
1 5
<210> 2654
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2654
Ile Ser Glu Glu Asp Leu Arg Lys
1 5
<210> 2655
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2655
Ile Ser Glu Gly Leu Pro Ala Leu Glu Phe Pro Asn Glu Lys
1 5 10
<210> 2656
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2656
Ile Ser Glu Ile Thr Asn Ile Val Ser Lys
1 5 10
<210> 2657
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2657
Ile Ser Glu Leu Ile Lys
1 5
<210> 2658
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2658
Ile Ser Phe Asp Glu Phe Ile Lys
1 5
<210> 2659
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2659
Ile Ser His Val Trp Gln Ser Ala Gly Ile Ser Lys
1 5 10
<210> 2660
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2660
Ile Ser Ile Glu Met His Gly Thr Leu Glu Asp Gln Leu Ser His Leu
1 5 10 15
Arg
<210> 2661
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2661
Ile Ser Ile Met Lys
1 5
<210> 2662
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2662
Ile Ser Leu Gly Pro Arg
1 5
<210> 2663
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2663
Ile Ser Leu Pro Glu Ser Leu Lys
1 5
<210> 2664
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2664
Ile Ser Leu Pro Glu Ser Leu Lys Arg
1 5
<210> 2665
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2665
Ile Ser Leu Pro Leu Gly Ser Glu Glu Arg Pro Phe Leu Arg
1 5 10
<210> 2666
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2666
Ile Ser Leu Gln Trp Leu Arg
1 5
<210> 2667
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2667
Ile Ser Leu Ser Gly Val His His Phe Ala Arg
1 5 10
<210> 2668
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2668
Ile Ser Met Leu Glu Lys
1 5
<210> 2669
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2669
Ile Ser Met Leu Glu Lys Ile Tyr Ile His Pro Arg
1 5 10
<210> 2670
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2670
Ile Ser Asn Ile Ile Lys
1 5
<210> 2671
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2671
Ile Ser Asn Ile Pro Asp Glu Tyr Phe Lys
1 5 10
<210> 2672
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2672
Ile Ser Asn Leu Leu Lys
1 5
<210> 2673
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2673
Ile Ser Pro Glu Gly Lys
1 5
<210> 2674
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2674
Ile Ser Pro Phe Ala Ser Asp Ile Arg
1 5
<210> 2675
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2675
Ile Ser Pro Asn Pro Lys
1 5
<210> 2676
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2676
Ile Ser Gln His Leu Asp Phe Ile Ser Ile Met Thr Tyr Asp Phe His
1 5 10 15
Gly Ala Trp Arg
20
<210> 2677
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2677
Ile Ser Gln Leu Thr Arg
1 5
<210> 2678
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2678
Ile Ser Ser Leu Thr Ser Glu Ile Met Lys
1 5 10
<210> 2679
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2679
Ile Ser Val Ala Gln Gly Ala Ser Lys
1 5
<210> 2680
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2680
Ile Ser Val Asp Lys
1 5
<210> 2681
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2681
Ile Ser Val Phe Lys
1 5
<210> 2682
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2682
Ile Ser Val Ile Arg Pro Ser Lys
1 5
<210> 2683
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2683
Ile Ser Val Thr Gln Pro Asp Ser Ile Val Gly Ile Val Ala Val Asp
1 5 10 15
Lys
<210> 2684
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2684
Ile Thr Ala Asn Leu Phe Arg
1 5
<210> 2685
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2685
Ile Thr Cys Thr Glu Glu Gly Trp Ser Pro Thr Pro Lys
1 5 10
<210> 2686
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2686
Ile Thr Asp Leu Ile Lys
1 5
<210> 2687
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2687
Ile Thr Asp Leu Ile Lys Asp Leu Asp Ser Gln Thr Met Met Val Leu
1 5 10 15
Val Asn Tyr Ile Phe Phe Lys
20
<210> 2688
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2688
Ile Thr Asp Asn Met Phe Cys Ala Gly Tyr Lys Pro Asp Glu Gly Lys
1 5 10 15
<210> 2689
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2689
Ile Thr Asp Asn Met Phe Cys Ala Gly Tyr Lys Pro Asp Glu Gly Lys
1 5 10 15
Arg
<210> 2690
<211> 25
<212> PRT
<213> Homo sapiens
<400> 2690
Ile Thr Asp Val Ile Pro Ser Glu Ala Ile Asn Glu Leu Thr Val Leu
1 5 10 15
Val Leu Val Asn Thr Ile Tyr Phe Lys
20 25
<210> 2691
<211> 29
<212> PRT
<213> Homo sapiens
<400> 2691
Ile Thr Asp Val Ile Pro Ser Glu Ala Ile Asn Glu Leu Thr Val Leu
1 5 10 15
Val Leu Val Asn Thr Ile Tyr Phe Lys Gly Leu Trp Lys
20 25
<210> 2692
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2692
Ile Thr Glu Ala Thr Lys
1 5
<210> 2693
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2693
Ile Thr Glu Asn Asp Ile Gln Ile Ala Leu Asp Asp Ala Lys
1 5 10
<210> 2694
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2694
Ile Thr Phe Glu Leu Val Tyr Glu Glu Leu Leu Lys
1 5 10
<210> 2695
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2695
Ile Thr Phe Glu Leu Val Tyr Glu Glu Leu Leu Lys Arg
1 5 10
<210> 2696
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2696
Ile Thr Phe Met Cys Asn Asp His Tyr Ile Leu Lys
1 5 10
<210> 2697
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2697
Ile Thr Phe Thr Leu Ser His Arg
1 5
<210> 2698
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2698
Ile Thr Gly Phe Leu Lys Pro Gly Lys
1 5
<210> 2699
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2699
Ile Thr Gly Lys Pro Ile Lys
1 5
<210> 2700
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2700
Ile Thr Gly Tyr Ile Ile Lys
1 5
<210> 2701
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2701
Ile Thr Gly Tyr Ile Ile Lys Tyr Glu Lys Pro Gly Ser Pro Pro Arg
1 5 10 15
<210> 2702
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2702
Ile Thr His Val His Val His Met Arg
1 5
<210> 2703
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2703
Ile Thr His Tyr Asn Tyr Leu Ile Leu Ser Lys
1 5 10
<210> 2704
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2704
Ile Thr Ile Pro Arg
1 5
<210> 2705
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2705
Ile Thr Ile Ser Lys
1 5
<210> 2706
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2706
Ile Thr Lys Asp Ile Leu Lys
1 5
<210> 2707
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2707
Ile Thr Lys Pro Ala Leu Leu Val Leu Asn His Glu Thr Ala Lys
1 5 10 15
<210> 2708
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2708
Ile Thr Leu Ile Ile Asn Trp Leu Gln Glu Ala Leu Ser Ser Ala Ser
1 5 10 15
Leu Ala His Met Lys
20
<210> 2709
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2709
Ile Thr Leu Leu Ser Ala Leu Val Glu Thr Arg
1 5 10
<210> 2710
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2710
Ile Thr Leu Leu Ser Ala Leu Val Glu Thr Arg Thr Ile Val Arg
1 5 10 15
<210> 2711
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2711
Ile Thr Leu Pro Asp Phe Arg
1 5
<210> 2712
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2712
Ile Thr Leu Pro Val Asp Phe Val Thr Ala Asp Lys Phe Asp Glu Asn
1 5 10 15
Ala Lys
<210> 2713
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2713
Ile Thr Leu Ser Lys
1 5
<210> 2714
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2714
Ile Thr Leu Ser Arg
1 5
<210> 2715
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2715
Ile Thr Leu Trp Asn Arg
1 5
<210> 2716
<211> 25
<212> PRT
<213> Homo sapiens
<400> 2716
Ile Thr Pro Gly Lys Pro Tyr Ile Leu Thr Val Pro Gly His Leu Asp
1 5 10 15
Glu Met Gln Leu Asp Ile Gln Ala Arg
20 25
<210> 2717
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2717
Ile Thr Pro Asn Leu Ala Glu Phe Ala Phe Ser Leu Tyr Arg
1 5 10
<210> 2718
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2718
Ile Thr Pro Ser Tyr Val Ala Phe Thr Pro Glu Gly Glu Arg
1 5 10
<210> 2719
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2719
Ile Thr Pro Thr Ile Thr Asn Phe Ala Leu Arg
1 5 10
<210> 2720
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2720
Ile Thr Gln Asp Ala Gln Leu Lys
1 5
<210> 2721
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2721
Ile Thr Gln Val Leu His Phe Thr Lys
1 5
<210> 2722
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2722
Ile Thr Gln Val Leu His Phe Thr Lys Asp Val Lys
1 5 10
<210> 2723
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2723
Ile Thr Ser Gly Leu His Ser Phe Gly Arg
1 5 10
<210> 2724
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2724
Ile Thr Thr Ala Lys
1 5
<210> 2725
<211> 28
<212> PRT
<213> Homo sapiens
<400> 2725
Ile Thr Thr Gly Gly Asp Val Ile Asn Asn Gly Leu Trp Asn Met Val
1 5 10 15
Ser Val Glu Glu Leu Glu His Ser Ile Ser Ile Lys
20 25
<210> 2726
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2726
Ile Thr Thr Thr Ser Pro Trp Met Phe Pro Ser Arg
1 5 10
<210> 2727
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2727
Ile Thr Val Ile Arg
1 5
<210> 2728
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2728
Ile Thr Val Leu Arg
1 5
<210> 2729
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2729
Ile Thr Val Val Ala Gly Glu His Asn Ile Glu Glu Thr Glu His Thr
1 5 10 15
Glu Gln Lys
<210> 2730
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2730
Ile Thr Val Val Ala Gly Glu His Asn Ile Glu Glu Thr Glu His Thr
1 5 10 15
Glu Gln Lys Arg
20
<210> 2731
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2731
Ile Thr Val Val Asp Ala Leu His Glu Ile Pro Val Lys
1 5 10
<210> 2732
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2732
Ile Thr Tyr Gly Glu Thr Gly Gly Asn Ser Pro Val Gln Glu Phe Thr
1 5 10 15
Val Pro Gly Ser Lys
20
<210> 2733
<211> 45
<212> PRT
<213> Homo sapiens
<400> 2733
Ile Thr Tyr Gly Glu Thr Gly Gly Asn Ser Pro Val Gln Glu Phe Thr
1 5 10 15
Val Pro Gly Ser Lys Ser Thr Ala Thr Ile Ser Gly Leu Lys Pro Gly
20 25 30
Val Asp Tyr Thr Ile Thr Val Tyr Ala Val Thr Gly Arg
35 40 45
<210> 2734
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2734
Ile Thr Tyr Tyr His Leu Ser Phe Pro Thr Asn Ile Gln Ala Pro Ala
1 5 10 15
Val Val Phe Arg
20
<210> 2735
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2735
Ile Val Ala Cys Ala Ser Tyr Lys Pro Ser Arg
1 5 10
<210> 2736
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2736
Ile Val Ala Asp Lys Asp Tyr Ser Val Thr Ala Asn Ser Lys
1 5 10
<210> 2737
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2737
Ile Val Ala Ile Lys Lys
1 5
<210> 2738
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2738
Ile Val Ala Pro Gly Lys
1 5
<210> 2739
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2739
Ile Val Ala Thr Lys Pro Leu Tyr Val Ala Leu Ala Gln Arg
1 5 10
<210> 2740
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2740
Ile Val Asp Gly Lys
1 5
<210> 2741
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2741
Ile Val Asp Leu Phe Ser Gly Leu Asp Ser Pro Ala Ile Leu Val Leu
1 5 10 15
Val Asn Tyr Ile Phe Phe Lys
20
<210> 2742
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2742
Ile Val Asp Leu Ile Lys
1 5
<210> 2743
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2743
Ile Val Asp Leu Leu Lys
1 5
<210> 2744
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2744
Ile Val Asp Leu Val Lys
1 5
<210> 2745
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2745
Ile Val Asp Leu Val Ser Glu Leu Lys
1 5
<210> 2746
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2746
Ile Val Asp Leu Val Ser Glu Leu Lys Lys
1 5 10
<210> 2747
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2747
Ile Val Phe Pro His Gly Ile Thr Leu Asp Leu Val Ser Arg
1 5 10
<210> 2748
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2748
Ile Val Gly Gly Lys
1 5
<210> 2749
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2749
Ile Val His Glu Tyr Ile Gly Gly Tyr Ile Phe Leu Ser Thr Arg
1 5 10 15
<210> 2750
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2750
Ile Val His Val Gly Leu Val Gln Asn Arg
1 5 10
<210> 2751
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2751
Ile Val Ile Glu Tyr Val Asp Arg
1 5
<210> 2752
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2752
Ile Val Leu Gly Gln Glu Gln Asp Ser Tyr Gly Gly Lys
1 5 10
<210> 2753
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2753
Ile Val Leu Gly Gln Glu Gln Asp Ser Tyr Gly Gly Lys Phe Asp Arg
1 5 10 15
<210> 2754
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2754
Ile Val Leu Ile Arg
1 5
<210> 2755
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2755
Ile Val Leu Ile Ser Gly Arg Arg
1 5
<210> 2756
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2756
Ile Val Leu Leu Arg
1 5
<210> 2757
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2757
Ile Val Leu Val Asp Asn Lys
1 5
<210> 2758
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2758
Ile Val Asn Leu Lys
1 5
<210> 2759
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2759
Ile Val Asn Leu Lys Glu Lys
1 5
<210> 2760
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2760
Ile Val Asn Val Leu Lys
1 5
<210> 2761
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2761
Ile Val Gln Ile Leu Pro Trp Glu Gln Asn Glu Gln Val Lys
1 5 10
<210> 2762
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2762
Ile Val Gln Ile Tyr Lys
1 5
<210> 2763
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2763
Ile Val Gln Ile Tyr Lys Asp Leu Leu Arg
1 5 10
<210> 2764
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2764
Ile Val Gln Leu Ile Gln Asp Thr Arg
1 5
<210> 2765
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2765
Ile Val Gln Ser His Gln Gln Thr Gly Arg
1 5 10
<210> 2766
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2766
Ile Val Ser Ser Ala Met Glu Pro Asp Arg
1 5 10
<210> 2767
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2767
Ile Val Ser Ser Ala Met Glu Pro Asp Arg Glu Tyr His Phe Gly Gln
1 5 10 15
Ala Val Arg
<210> 2768
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2768
Ile Val Val Glu Asp Val Asp Glu Pro Pro Val Phe Ser Lys
1 5 10
<210> 2769
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2769
Ile Val Val Glu Glu Lys
1 5
<210> 2770
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2770
Ile Val Val Val Thr Ala Gly Val Arg
1 5
<210> 2771
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2771
Ile Trp Asp Val Val Glu Lys
1 5
<210> 2772
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2772
Ile Trp His His Thr Phe Tyr Asn Glu Leu Arg
1 5 10
<210> 2773
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2773
Ile Trp Leu Asp Asn Val Arg
1 5
<210> 2774
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2774
Ile Tyr Ala Ile Leu Gly Lys
1 5
<210> 2775
<211> 44
<212> PRT
<213> Homo sapiens
<400> 2775
Ile Tyr Glu Asp His Asp Ala Thr Gln Gln Leu Gln Gly Phe Tyr Ser
1 5 10 15
Gln Val Ala Lys Pro Leu Leu Val Asp Val Asp Leu Gln Tyr Pro Gln
20 25 30
Asp Ala Val Leu Ala Leu Thr Gln Asn His His Lys
35 40
<210> 2776
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2776
Ile Tyr Glu Gly Ala Tyr His Val Leu His Lys
1 5 10
<210> 2777
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2777
Ile Tyr Gly Asn Gln Asp Thr Ser Ser Gln Leu Lys
1 5 10
<210> 2778
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2778
Ile Tyr Gly Asn Gln Asp Thr Ser Ser Gln Leu Lys Lys
1 5 10
<210> 2779
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2779
Ile Tyr Gly Pro Ser Asp Ser Ala Ser Arg
1 5 10
<210> 2780
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2780
Ile Tyr Gly Gln Arg Gln Trp Lys
1 5
<210> 2781
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2781
Ile Tyr His Ser His Ile Asp Ala Pro Lys
1 5 10
<210> 2782
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2782
Ile Tyr Ile His Pro Arg
1 5
<210> 2783
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2783
Ile Tyr Ile Ser Gly Met Ala Pro Arg Pro Ser Leu Ala Lys
1 5 10
<210> 2784
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2784
Ile Tyr Ile Ser Gly Met Ala Pro Arg Pro Ser Leu Ala Lys Lys
1 5 10 15
<210> 2785
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2785
Ile Tyr Leu Gln Pro Gly Arg
1 5
<210> 2786
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2786
Ile Tyr Leu Ser Asp Asn Leu Lys
1 5
<210> 2787
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2787
Ile Tyr Leu Tyr Thr Leu Asn Asp Asn Ala Arg
1 5 10
<210> 2788
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2788
Ile Tyr Met Ala Asp Leu Glu Ser Ala Leu His Tyr Ile Leu Arg
1 5 10 15
<210> 2789
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2789
Ile Tyr Pro Thr Val Asn Cys Gln Pro Leu Gly Met Ile Ser Leu Met
1 5 10 15
Lys
<210> 2790
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2790
Ile Tyr Ser Gly Ile Leu Asn Leu Ser Asp Ile Thr Lys
1 5 10
<210> 2791
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2791
Ile Tyr Ser Ile Leu Lys
1 5
<210> 2792
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2792
Ile Tyr Ser Leu Trp Glu His Ser Thr Lys
1 5 10
<210> 2793
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2793
Ile Tyr Thr Ser Pro Thr Trp Ser Ala Phe Val Thr Asp Ser Ser Trp
1 5 10 15
Ser Ala Arg
<210> 2794
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2794
Ile Tyr Val Asp Asp Gly Leu Ile Ser Leu Gln Val Lys
1 5 10
<210> 2795
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2795
Ile Tyr Trp Tyr Gln Gln Lys Pro Gly Ser Leu Pro Arg
1 5 10
<210> 2796
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2796
Ile Tyr Tyr Asn Gly Asp Lys
1 5
<210> 2797
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2797
Lys Ala Ala Asp Asp Thr Trp Glu Pro Phe Ala Ser Gly Lys
1 5 10
<210> 2798
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2798
Lys Ala Ala Ile Glu Lys
1 5
<210> 2799
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2799
Lys Ala Ala Ile Ser Gly Glu Asn Ala Gly Leu Val Arg
1 5 10
<210> 2800
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2800
Lys Ala Ala Leu Glu Lys
1 5
<210> 2801
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2801
Lys Ala Asp Gly Ser Tyr Ala Ala Trp Leu Ser Arg
1 5 10
<210> 2802
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2802
Lys Ala Glu Glu Glu His Leu Gly Ile Leu Gly Pro Gln Leu His Ala
1 5 10 15
Asp Val Gly Asp Lys
20
<210> 2803
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2803
Lys Ala Glu Gly Ala Ala Thr Glu Glu Glu Gly Thr Pro Lys
1 5 10
<210> 2804
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2804
Lys Ala Glu Thr Gly Asp Thr Val Leu Lys
1 5 10
<210> 2805
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2805
Lys Ala Phe Asp Ile Cys Pro Leu Val Lys
1 5 10
<210> 2806
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2806
Lys Ala Gly Thr Glu Leu Val Asn Phe Leu Ser Tyr Phe Val Glu Leu
1 5 10 15
Gly Thr Gln Pro Ala Thr Gln
20
<210> 2807
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2807
Lys Ala Leu Ser Asp Ala Ile Lys
1 5
<210> 2808
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2808
Lys Ala Leu Tyr Leu Gln Tyr Thr Asp Glu Thr Phe Arg
1 5 10
<210> 2809
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2809
Lys Ala Met Ala Val Glu Asp Ile Ile Ser Arg
1 5 10
<210> 2810
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2810
Lys Ala Pro Pro Ser Gln Pro Pro Arg
1 5
<210> 2811
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2811
Lys Ala Gln Gln Glu Leu Glu Glu Gln Thr Arg
1 5 10
<210> 2812
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2812
Lys Ala Ser Asp Ala Glu Gly Asp Val Ala Ala Leu Asn Arg
1 5 10
<210> 2813
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2813
Lys Ala Ser Tyr Leu Asp Cys Ile Arg
1 5
<210> 2814
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2814
Lys Ala Thr Asp Ala Glu Ala Asp Val Ala Ser Leu Asn Arg
1 5 10
<210> 2815
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2815
Lys Ala Thr Glu Asp Glu Gly Ser Glu Gln Lys
1 5 10
<210> 2816
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2816
Lys Ala Thr Val Val Tyr Gln Gly Glu Arg
1 5 10
<210> 2817
<211> 28
<212> PRT
<213> Homo sapiens
<400> 2817
Lys Asp Asp Ile Met Leu Asp Glu Gly Met Leu Gln Ser Leu Met Glu
1 5 10 15
Leu Pro Asp Gln Tyr Asn Tyr Gly Met Tyr Ala Lys
20 25
<210> 2818
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2818
Lys Asp Asp Pro Leu Thr Asn Leu Asn Thr Ala Phe Asp Val Ala Glu
1 5 10 15
Lys
<210> 2819
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2819
Lys Asp Glu Ile Leu Gly Ile Ala Asn Asn Arg
1 5 10
<210> 2820
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2820
Lys Asp Gly Thr His Val Val Glu Asn Val Asp Ala Thr His Ile Gly
1 5 10 15
Lys
<210> 2821
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2821
Lys Asp His Ser Gly Gln Val Phe Ser Val Val Ser Asn Gly Lys
1 5 10 15
<210> 2822
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2822
Lys Asp Leu Glu Ser Ile Ile Lys
1 5
<210> 2823
<211> 22
<212> PRT
<213> Homo sapiens
<400> 2823
Lys Asp Leu Tyr Ala Asn Thr Val Leu Ser Gly Gly Thr Thr Met Tyr
1 5 10 15
Pro Gly Ile Ala Asp Arg
20
<210> 2824
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2824
Lys Asp Asn Glu Gln His Val Phe Lys
1 5
<210> 2825
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2825
Lys Asp Asn Ser Val His Trp Glu Arg Pro Gln Lys Pro Lys
1 5 10
<210> 2826
<211> 29
<212> PRT
<213> Homo sapiens
<400> 2826
Lys Asp Pro Glu Gly Leu Phe Leu Gln Asp Asn Ile Val Ala Glu Phe
1 5 10 15
Ser Val Asp Glu Thr Gly Gln Met Ser Ala Thr Ala Lys
20 25
<210> 2827
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2827
Lys Asp Ser Gly Phe Gln Met Asn Gln Leu Arg
1 5 10
<210> 2828
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2828
Lys Asp Ser Ser Phe Ile Arg
1 5
<210> 2829
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2829
Lys Asp Ser Ser Leu Cys Lys
1 5
<210> 2830
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2830
Lys Asp Thr Val Ile Lys Pro Leu Leu Val Glu Pro Glu Gly Leu Glu
1 5 10 15
Lys
<210> 2831
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2831
Lys Asp Val Gly Arg Pro Gln Pro Gly Arg
1 5 10
<210> 2832
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2832
Lys Asp Val Leu Glu Thr Phe Thr Val Lys
1 5 10
<210> 2833
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2833
Lys Asp Val Leu Met Val Leu Val Asn Tyr Ile Tyr Phe Lys
1 5 10
<210> 2834
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2834
Lys Glu Ala Glu Ser Ser Pro Phe Val Glu Arg
1 5 10
<210> 2835
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2835
Lys Glu Ala Gly Ile Pro Glu Phe Tyr Asp Tyr Asp Val Ala Leu Ile
1 5 10 15
Lys
<210> 2836
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2836
Lys Glu Asp Leu Val Phe Ile Phe Trp Ala Pro Glu Ser Ala Pro Leu
1 5 10 15
Lys
<210> 2837
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2837
Lys Glu Glu Glu Leu Gln Ala Ala Leu Ala Arg
1 5 10
<210> 2838
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2838
Lys Glu Glu Phe His Glu Gln Ser Phe Arg
1 5 10
<210> 2839
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2839
Lys Glu Phe Asp His Asn Ser Asn Ile Arg
1 5 10
<210> 2840
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2840
Lys Glu Phe Gln Glu Gly Leu Lys
1 5
<210> 2841
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2841
Lys Glu Gly Gly Leu Gly Pro Leu Asn Ile Pro Leu Leu Ala Asp Val
1 5 10 15
Thr Arg
<210> 2842
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2842
Lys Glu Gly Tyr Ser Asn Ile Ser Tyr Ile Val Val Asn His Gln Gly
1 5 10 15
Ile Ser Ser Arg
20
<210> 2843
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2843
Lys Glu Leu Glu Leu Gln Ile Gly Asn Ala Leu Phe Ile Gly Lys
1 5 10 15
<210> 2844
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2844
Lys Glu Leu Asn Ser Phe Leu Glu Ser Gln Lys
1 5 10
<210> 2845
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2845
Lys Glu Leu Ser Ser Phe Ile Asp Lys
1 5
<210> 2846
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2846
Lys Glu Met Gln Pro Thr His Pro Ile Arg
1 5 10
<210> 2847
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2847
Lys Glu Thr Phe Asp Val Thr Leu Glu Pro Leu Ser Phe Lys
1 5 10
<210> 2848
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2848
Lys Glu Val Pro Val Ala Ile Lys
1 5
<210> 2849
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2849
Lys Glu Val Tyr Ile Lys
1 5
<210> 2850
<211> 26
<212> PRT
<213> Homo sapiens
<400> 2850
Lys Glu Val Tyr Met Pro Ser Ser Ile Phe Gln Asp Asp Phe Val Ile
1 5 10 15
Pro Asp Ile Ser Glu Pro Gly Thr Trp Lys
20 25
<210> 2851
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2851
Lys Glu Tyr Glu Met Lys
1 5
<210> 2852
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2852
Lys Phe Asp Leu Gly Gln Asp Val Ile Asp Phe Thr Gly His Ala Leu
1 5 10 15
Ala Leu Tyr Arg
20
<210> 2853
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2853
Lys Phe Asp Gln Leu Leu Ala Glu Glu Lys
1 5 10
<210> 2854
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2854
Lys Phe Gly Pro Val Val Ala Pro Lys Pro Lys
1 5 10
<210> 2855
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2855
Lys Phe Ile Phe Thr Arg
1 5
<210> 2856
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2856
Lys Phe Ile Gln Lys
1 5
<210> 2857
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2857
Lys Phe Leu Leu Tyr Ala Arg
1 5
<210> 2858
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2858
Lys Phe Pro Ser Gly Thr Phe Glu Gln Val Ser Gln Leu Val Lys
1 5 10 15
<210> 2859
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2859
Lys Phe Ser Glu Trp Gly Asn Asn Ala Phe Phe Tyr Tyr Phe Glu His
1 5 10 15
Arg
<210> 2860
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2860
Lys Phe Ser Leu Asp Ala Leu Ile Thr His Val Leu Pro Phe Glu Lys
1 5 10 15
<210> 2861
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2861
Lys Phe Ser Tyr Ser Ser Gly His Val His Leu Ser Ser Glu Asn Lys
1 5 10 15
<210> 2862
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2862
Lys Phe Val Ala Val Leu Ala Lys
1 5
<210> 2863
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2863
Lys Phe Val Ile Lys Pro Ile Asp Lys
1 5
<210> 2864
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2864
Lys Phe Val Gln Gly Lys
1 5
<210> 2865
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2865
Lys Phe Tyr Asn Gln Val Ser Thr Pro Leu Leu Arg
1 5 10
<210> 2866
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2866
Lys Gly Asp Ile Tyr Asn Glu Lys
1 5
<210> 2867
<211> 22
<212> PRT
<213> Homo sapiens
<400> 2867
Lys Gly Asp Val Val Ile Val Leu Thr Gly Trp Arg Pro Gly Ser Gly
1 5 10 15
Phe Thr Asn Thr Met Arg
20
<210> 2868
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2868
Lys Gly Glu Ile Thr Gly Glu Val Arg
1 5
<210> 2869
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2869
Lys Gly Glu Val Leu Pro Leu Pro Glu Ala Asn Phe Pro Ser Phe Pro
1 5 10 15
Leu Pro His His Lys
20
<210> 2870
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2870
Lys Gly Glu Trp Val Ala Leu Asn Pro Leu Arg
1 5 10
<210> 2871
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2871
Lys Gly Gly Asp Gly Ile Lys Pro Pro Pro Ile Ile Gly Arg
1 5 10
<210> 2872
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2872
Lys Gly Gly Glu Thr Ser Glu Met Tyr Leu Ile Gln Pro Asp Ser Ser
1 5 10 15
Val Lys Pro Tyr Arg
20
<210> 2873
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2873
Lys Gly Gly Val Ala Ser Gly Phe Lys
1 5
<210> 2874
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2874
Lys Gly His Ile Tyr Gln Gly Ser Glu Ala Asp Ser Val Phe Ser Gly
1 5 10 15
Phe Leu Ile Phe Pro Ser Ala
20
<210> 2875
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2875
Lys Gly His Val Ser Phe Lys Pro Ser Leu Asp Gln Gln Arg
1 5 10
<210> 2876
<211> 27
<212> PRT
<213> Homo sapiens
<400> 2876
Lys Gly Ile Ser Thr Ser Ala Ala Ser Pro Ala Val Gly Thr Val Gly
1 5 10 15
Met Asp Met Asp Glu Asp Asp Asp Phe Ser Lys
20 25
<210> 2877
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2877
Lys Gly Ile Val Asp Gln Ser Gln Gln Ala Tyr Gln Glu Ala Phe Glu
1 5 10 15
Ile Ser Lys
<210> 2878
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2878
Lys Gly Ile Tyr Ser Phe Asn Phe His Val Val Lys
1 5 10
<210> 2879
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2879
Lys Gly Leu Glu Gln Leu Leu Val Gly Gly Ser His Leu Lys
1 5 10
<210> 2880
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2880
Lys Gly Asn Phe Asn Tyr Ile Glu Phe Thr Arg
1 5 10
<210> 2881
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2881
Lys Gly Asn Val Ala Thr Glu Ile Ser Thr Glu Arg
1 5 10
<210> 2882
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2882
Lys Gly Pro Ala Ala Ile Gln Lys
1 5
<210> 2883
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2883
Lys Gly Pro Gly Pro Gly Gly Pro Gly Gly Ala Gly Val Ala Arg
1 5 10 15
<210> 2884
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2884
Lys Gly Gln Ala Val Asp Tyr Glu Gly Ser Arg
1 5 10
<210> 2885
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2885
Lys Gly Gln Phe Pro Ile Leu Ser Ile Thr Trp Glu His Ala Gly Arg
1 5 10 15
<210> 2886
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2886
Lys Gly Ser Leu His Ala Asn Gly Arg
1 5
<210> 2887
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2887
Lys Gly Ser Pro Val Asn Ser Leu Phe Val Ala Pro Ala Val Thr Pro
1 5 10 15
Val Lys
<210> 2888
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2888
Lys Gly Thr Leu Thr Glu Gly Gly Thr Gln Lys
1 5 10
<210> 2889
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2889
Lys Gly Thr Val Val Ala Glu Lys
1 5
<210> 2890
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2890
Lys Gly Val Cys Glu Glu Thr Ser Gly Ala Tyr Glu Lys
1 5 10
<210> 2891
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2891
Lys Gly Val Glu Leu Lys
1 5
<210> 2892
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2892
Lys Gly Val Asn Leu Pro Gly Ala Ala Val Asp Leu Pro Ala Val Ser
1 5 10 15
Glu Lys
<210> 2893
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2893
Lys Gly Tyr Thr Gln Gln Leu Ala Phe Arg
1 5 10
<210> 2894
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2894
Lys His Glu Ala Phe Glu Ser Asp Leu Ala Ala His Gln Asp Arg
1 5 10 15
<210> 2895
<211> 23
<212> PRT
<213> Homo sapiens
<400> 2895
Lys Ile Asp Ala Ala Gln Asn Trp Leu Ala Asp Pro Asn Gly Gly Pro
1 5 10 15
Glu Gly Glu Glu Gln Ile Arg
20
<210> 2896
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2896
Lys Ile Asp Glu Leu Asn Lys
1 5
<210> 2897
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2897
Lys Ile Glu Glu Ile Ala Ala Lys
1 5
<210> 2898
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2898
Lys Ile Glu Ser Phe Gly Ser Lys
1 5
<210> 2899
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2899
Lys Ile Phe Gln Ala His Lys
1 5
<210> 2900
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2900
Lys Ile Ile Phe Lys
1 5
<210> 2901
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2901
Lys Ile Ile Ser Asp Tyr His Gln Gln Phe Arg
1 5 10
<210> 2902
<211> 21
<212> PRT
<213> Homo sapiens
<400> 2902
Lys Ile Leu His Val Asp Asn His Ile Gly Ile Ser Ile Ala Gly Leu
1 5 10 15
Thr Ala Asp Ala Arg
20
<210> 2903
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2903
Lys Ile Met Ala Asp Ser Gly Pro Ile Tyr Asp Lys
1 5 10
<210> 2904
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2904
Lys Ile Asn Val Ile Val Leu Arg
1 5
<210> 2905
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2905
Lys Ile Pro Val Val Phe Arg
1 5
<210> 2906
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2906
Lys Ile Gln Ala Leu Gln Gln Gln Ala Asp Glu Ala Glu Asp Arg
1 5 10 15
<210> 2907
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2907
Lys Ile Gln Ala Ser Thr Met Ala Phe Lys
1 5 10
<210> 2908
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2908
Lys Ile Gln Ile Gln Arg
1 5
<210> 2909
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2909
Lys Ile Gln Gln Thr Arg
1 5
<210> 2910
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2910
Lys Ile Gln Thr Gln Leu Gln Arg
1 5
<210> 2911
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2911
Lys Ile Ser Ser Ile Gln Ser Ile Val Pro Ala Leu Glu Ile Ala Asn
1 5 10 15
Ala His Arg
<210> 2912
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2912
Lys Ile Thr Ala Ile Ile Thr Gln Gly Cys Lys
1 5 10
<210> 2913
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2913
Lys Ile Val Gly Ala Met Val Gln Ile Ile Thr Tyr Arg
1 5 10
<210> 2914
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2914
Lys Ile Val Asn Ala Lys
1 5
<210> 2915
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2915
Lys Ile Val Gln Lys
1 5
<210> 2916
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2916
Lys Ile Tyr Leu Asp Glu Lys
1 5
<210> 2917
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2917
Lys Ile Tyr Pro Thr Val Asn Cys Gln Pro Leu Gly Met Ile Ser Leu
1 5 10 15
Met Lys
<210> 2918
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2918
Lys Lys Pro Gly Ile Tyr Thr Arg
1 5
<210> 2919
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2919
Lys Leu Ala Gly Asp Glu Ser Ala Asp
1 5
<210> 2920
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2920
Lys Leu Ala Val Asn Met Val Pro Phe Pro Arg
1 5 10
<210> 2921
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2921
Lys Leu Cys Met Ala Ala Leu Lys
1 5
<210> 2922
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2922
Lys Leu Cys Gln Gly Leu Phe Phe Arg
1 5
<210> 2923
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2923
Lys Leu Asp Gly Ile Cys Trp Gln Val Arg
1 5 10
<210> 2924
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2924
Lys Leu Glu Ala Met Thr Asn Ser Lys
1 5
<210> 2925
<211> 24
<212> PRT
<213> Homo sapiens
<400> 2925
Lys Leu Glu Phe Ala Leu Leu Phe Leu Val Phe Asp Glu Asn Glu Ser
1 5 10 15
Trp Tyr Leu Asp Asp Asn Ile Lys
20
<210> 2926
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2926
Lys Leu Glu Leu His Leu Pro Lys
1 5
<210> 2927
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2927
Lys Leu Glu Gln Leu Lys Pro Arg
1 5
<210> 2928
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2928
Lys Leu Glu Gln Thr Lys
1 5
<210> 2929
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2929
Lys Leu Glu Ser Leu Leu Lys
1 5
<210> 2930
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2930
Lys Leu Phe Phe Phe Ser Gly Arg
1 5
<210> 2931
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2931
Lys Leu Phe Gly Thr Ser Gly Gln Lys
1 5
<210> 2932
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2932
Lys Leu Phe Pro Asn Phe Leu Lys
1 5
<210> 2933
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2933
Lys Leu Gly Leu Val Phe Asp Asp Val Val Gly Ile Val Glu Ile Ile
1 5 10 15
Asn Ser Lys
<210> 2934
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2934
Lys Leu Gly Gln Ser Leu Asp Cys Asn Ala Glu Val Tyr Val Val Pro
1 5 10 15
Trp Glu Lys
<210> 2935
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2935
Lys Leu Gly Ser Tyr Glu His Arg
1 5
<210> 2936
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2936
Lys Leu Ile Ala Ser Met Ser Ser Asp Ser Leu Arg
1 5 10
<210> 2937
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2937
Lys Leu Ile Asn Asp Tyr Val Lys
1 5
<210> 2938
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2938
Lys Leu Ile Pro Ile Thr Ile Ile Lys
1 5
<210> 2939
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2939
Lys Leu Ile Ser Val Asp Thr Glu His Ser Asn Ile Tyr Leu Gln Asn
1 5 10 15
Gly Pro Asp Arg
20
<210> 2940
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2940
Lys Leu Ile Thr Ser Met Arg
1 5
<210> 2941
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2941
Lys Leu Leu Phe Lys
1 5
<210> 2942
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2942
Lys Leu Leu Pro Asp Asp Pro Tyr Glu Lys
1 5 10
<210> 2943
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2943
Lys Leu Leu Thr Phe Lys
1 5
<210> 2944
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2944
Lys Leu Leu Tyr Lys
1 5
<210> 2945
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2945
Lys Leu Asn Ala Phe Gly Asn Ala Phe Leu Asn Arg
1 5 10
<210> 2946
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2946
Lys Leu Asn Gln Ala Leu Leu Asp Leu His Ala Leu Gly Ser Ala Arg
1 5 10 15
<210> 2947
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2947
Lys Leu Asn Val Thr Glu Gln Glu Lys
1 5
<210> 2948
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2948
Lys Leu Pro Pro Gly Leu Leu Ala Asn Phe Thr Leu Leu Arg
1 5 10
<210> 2949
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2949
Lys Leu Gln Ser Thr Thr Val Met Asn Pro Tyr Met Lys
1 5 10
<210> 2950
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2950
Lys Leu Gln Thr Asp Ile Lys
1 5
<210> 2951
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2951
Lys Leu Ser Glu Leu Leu Arg
1 5
<210> 2952
<211> 27
<212> PRT
<213> Homo sapiens
<400> 2952
Lys Leu Ser Glu Asn Thr Asp Phe Leu Ala Pro Gly Val Ser Ser Phe
1 5 10 15
Thr Asp Ser Asn Gln Gln Glu Ser Ile Thr Lys
20 25
<210> 2953
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2953
Lys Leu Ser Phe Phe Cys Leu Ala Gly Tyr Thr Thr Glu Ser Gly Arg
1 5 10 15
<210> 2954
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2954
Lys Leu Ser Phe Tyr Tyr Leu Ile Met Ala Lys
1 5 10
<210> 2955
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2955
Lys Leu Ser Ser Trp Val Leu Leu Met Lys
1 5 10
<210> 2956
<211> 6
<212> PRT
<213> Homo sapiens
<400> 2956
Lys Leu Thr Ile Phe Lys
1 5
<210> 2957
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2957
Lys Leu Thr Ile Ser Glu Gln Asn Ile Gln Arg
1 5 10
<210> 2958
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2958
Lys Leu Val Ala Ala Ser Gln Ala Ala Leu Gly Leu
1 5 10
<210> 2959
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2959
Lys Leu Val Asp Thr Leu Pro Gln Lys Pro Arg
1 5 10
<210> 2960
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2960
Lys Leu Val Ile Ile Glu Gly Asp Leu Glu Arg
1 5 10
<210> 2961
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2961
Lys Leu Val Ile Leu Glu Gly Glu Leu Glu Arg
1 5 10
<210> 2962
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2962
Lys Leu Val Leu Ser Ser Glu Lys
1 5
<210> 2963
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2963
Lys Leu Val Pro Phe Ala Thr Glu Leu His Glu Arg
1 5 10
<210> 2964
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2964
Lys Leu Trp Ala Tyr Leu Thr Ile Asn Gln Leu Leu Ala Glu Arg
1 5 10 15
<210> 2965
<211> 19
<212> PRT
<213> Homo sapiens
<400> 2965
Lys Leu Tyr His Ser Glu Ala Phe Thr Val Asn Phe Gly Asp Thr Glu
1 5 10 15
Glu Ala Lys
<210> 2966
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2966
Lys Leu Tyr Leu Lys
1 5
<210> 2967
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2967
Lys Met Asp Ala His Pro Pro Arg
1 5
<210> 2968
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2968
Lys Met Glu Ile Leu His Pro Gly Lys
1 5
<210> 2969
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2969
Lys Met Gly Leu Ala Phe Glu Ser Thr Lys
1 5 10
<210> 2970
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2970
Lys Met Leu Glu Glu Ile Met Lys
1 5
<210> 2971
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2971
Lys Met Ser Met Lys
1 5
<210> 2972
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2972
Lys Met Thr Ser Asn Phe Pro Val Asp Leu Ser Asp Tyr Pro Lys
1 5 10 15
<210> 2973
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2973
Lys Met Thr Val Thr Asp Gln Val Asn Cys Pro Lys
1 5 10
<210> 2974
<211> 16
<212> PRT
<213> Homo sapiens
<400> 2974
Lys Met Tyr Phe Asp Ala Val Gln Ala Ile Glu Thr His Leu Ile Arg
1 5 10 15
<210> 2975
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2975
Lys Asn Ala Glu Glu Leu Lys
1 5
<210> 2976
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2976
Lys Asn Glu Ile Asp Leu Glu Ser Glu Leu Lys
1 5 10
<210> 2977
<211> 5
<212> PRT
<213> Homo sapiens
<400> 2977
Lys Asn Leu Tyr Lys
1 5
<210> 2978
<211> 17
<212> PRT
<213> Homo sapiens
<400> 2978
Lys Asn Gln Gly Ile Leu Glu Phe Tyr Gly Asp Asp Ile Ala Leu Leu
1 5 10 15
Lys
<210> 2979
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2979
Lys Asn Thr Pro Ile Asp Gly Lys
1 5
<210> 2980
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2980
Lys Asn Trp Ile Gln Tyr Lys
1 5
<210> 2981
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2981
Lys Pro Ala Ile Thr Tyr Gly Thr Arg
1 5
<210> 2982
<211> 14
<212> PRT
<213> Homo sapiens
<400> 2982
Lys Pro Ala Leu Asn Leu Ile Tyr Lys Pro Tyr Gln Ile Arg
1 5 10
<210> 2983
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2983
Lys Pro Asp Gly Thr Leu Val Ser Phe Thr Ala Asp Phe Lys Lys
1 5 10 15
<210> 2984
<211> 12
<212> PRT
<213> Homo sapiens
<400> 2984
Lys Pro Asp Gly Tyr Asp Tyr Tyr Ala Phe Ser Lys
1 5 10
<210> 2985
<211> 11
<212> PRT
<213> Homo sapiens
<400> 2985
Lys Pro Asp Gln His Phe Lys Pro Tyr Leu Lys
1 5 10
<210> 2986
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2986
Lys Pro Asp Val Ser His Gly Glu Met Val Ser Gly Phe Gly Pro Ile
1 5 10 15
Tyr Asn Tyr Lys
20
<210> 2987
<211> 26
<212> PRT
<213> Homo sapiens
<400> 2987
Lys Pro Asp Val Ser His Gly Glu Met Val Ser Gly Phe Gly Pro Ile
1 5 10 15
Tyr Asn Tyr Lys Asp Thr Ile Val Phe Lys
20 25
<210> 2988
<211> 8
<212> PRT
<213> Homo sapiens
<400> 2988
Lys Pro Glu Leu Val Asn Gly Arg
1 5
<210> 2989
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2989
Lys Pro Phe Leu Leu Leu Ala Ile Lys
1 5
<210> 2990
<211> 9
<212> PRT
<213> Homo sapiens
<400> 2990
Lys Pro Phe Tyr Leu Tyr Thr Gly Arg
1 5
<210> 2991
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2991
Lys Pro Gly Ala Ser Val Lys
1 5
<210> 2992
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2992
Lys Pro Gly Ala Thr Val Lys
1 5
<210> 2993
<211> 15
<212> PRT
<213> Homo sapiens
<400> 2993
Lys Pro Gly Ile Asn Val Ala Ser Asp Trp Ser Ile His Leu Arg
1 5 10 15
<210> 2994
<211> 7
<212> PRT
<213> Homo sapiens
<400> 2994
Lys Pro Gly Ile Tyr Thr Arg
1 5
<210> 2995
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2995
Lys Pro Ile Ile Gly Ile Leu Met Gln Lys
1 5 10
<210> 2996
<211> 13
<212> PRT
<213> Homo sapiens
<400> 2996
Lys Pro Ile Trp Leu Ser Gln Met Ser Cys Ser Gly Arg
1 5 10
<210> 2997
<211> 20
<212> PRT
<213> Homo sapiens
<400> 2997
Lys Pro Lys Met Cys Pro Gln Leu Gln Gln Tyr Glu Met His Gly Pro
1 5 10 15
Glu Gly Leu Arg
20
<210> 2998
<211> 10
<212> PRT
<213> Homo sapiens
<400> 2998
Lys Pro Leu Asn Thr Glu Gly Val Met Lys
1 5 10
<210> 2999
<211> 18
<212> PRT
<213> Homo sapiens
<400> 2999
Lys Pro Leu Thr Ser Ser Ser Ala Ala Pro Gln Arg Pro Ile Ser Thr
1 5 10 15
Gln Arg
<210> 3000
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3000
Lys Pro Pro Phe Ser Asp Lys Pro Ser Ile Pro Ala Gly Arg
1 5 10
<210> 3001
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3001
Lys Pro Pro Val Pro Lys
1 5
<210> 3002
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3002
Lys Pro Gln Asp Phe Leu Glu Glu Leu Lys
1 5 10
<210> 3003
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3003
Lys Pro Gln Ser Leu Thr Lys
1 5
<210> 3004
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3004
Lys Pro Ser Leu Ser Val Gln Pro Gly Pro Val Val Ala Pro Gly Glu
1 5 10 15
Lys
<210> 3005
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3005
Lys Pro Val Ala Phe Ser Asp Tyr Ile His Pro Val Cys Leu Pro Asp
1 5 10 15
Arg
<210> 3006
<211> 29
<212> PRT
<213> Homo sapiens
<400> 3006
Lys Pro Val Ala Phe Ser Asp Tyr Ile His Pro Val Cys Leu Pro Asp
1 5 10 15
Arg Glu Thr Ala Ala Ser Leu Leu Gln Ala Gly Tyr Lys
20 25
<210> 3007
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3007
Lys Pro Val Asp Glu Tyr Lys
1 5
<210> 3008
<211> 22
<212> PRT
<213> Homo sapiens
<400> 3008
Lys Pro Val Asp Glu Tyr Lys Asp Cys His Leu Ala Gln Val Pro Ser
1 5 10 15
His Thr Val Val Ala Arg
20
<210> 3009
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3009
Lys Pro Val Glu Glu Tyr Ala Asn Cys His Leu Ala Arg
1 5 10
<210> 3010
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3010
Lys Pro Tyr Asn Phe Leu Lys
1 5
<210> 3011
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3011
Lys Pro Tyr Asn Val Glu Ser Tyr Thr Pro Gln Thr Gln Gly Lys
1 5 10 15
<210> 3012
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3012
Lys Pro Tyr Asn Val Glu Ser Tyr Thr Pro Gln Thr Gln Gly Lys Tyr
1 5 10 15
Glu Phe Ile Leu Lys
20
<210> 3013
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3013
Lys Gln Glu Leu Ser Glu Ala Glu Gln Ala Thr Arg
1 5 10
<210> 3014
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3014
Lys Gln Gly Ile Gln Lys
1 5
<210> 3015
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3015
Lys Gln Ile Asn Asp Tyr Val Glu Lys
1 5
<210> 3016
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3016
Lys Gln Ile Ser Asn Leu Gln Gln Ser Ile Ser Asp Ala Glu Gln Arg
1 5 10 15
<210> 3017
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3017
Lys Gln Leu Gly Ala Gly Ser Ile Glu Glu Cys Ala Ala Lys
1 5 10
<210> 3018
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3018
Lys Gln Leu Val Glu Ile Glu Lys
1 5
<210> 3019
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3019
Lys Gln Pro Tyr Asn Asn Leu Lys
1 5
<210> 3020
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3020
Lys Gln Ser Glu Pro Leu Glu Ile Thr Leu Leu Ala Pro Glu Arg
1 5 10 15
<210> 3021
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3021
Lys Gln Thr Ala Cys Lys Pro Glu Ile Ala Tyr Ala Tyr Lys
1 5 10
<210> 3022
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3022
Lys Gln Thr Ala Leu Val Glu Leu Val Lys
1 5 10
<210> 3023
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3023
Lys Gln Val Thr Pro Leu Phe Ile His Phe Arg
1 5 10
<210> 3024
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3024
Lys Gln Trp Ile Asn Lys
1 5
<210> 3025
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3025
Lys Ser Ala Ser Asp Leu Thr Trp Asp Asn Leu Lys
1 5 10
<210> 3026
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3026
Lys Ser Asp Ile Asp Glu Ile Val Leu Val Gly Gly Ser Thr Arg
1 5 10 15
<210> 3027
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3027
Lys Ser Asp Leu Gln Lys
1 5
<210> 3028
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3028
Lys Ser Asp Val Gly Phe Leu Pro Pro Phe Pro Thr Leu Asp Pro Glu
1 5 10 15
Glu Lys
<210> 3029
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3029
Lys Ser Ile Ser Ala Ala Leu Glu His Lys
1 5 10
<210> 3030
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3030
Lys Ser Leu Ser Ser Met Thr Arg
1 5
<210> 3031
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3031
Lys Ser Pro Gln Glu Leu Leu Cys Gly Ala Ser Leu Ile Ser Asp Arg
1 5 10 15
<210> 3032
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3032
Lys Ser Gln Leu Val Tyr Gln Ser Arg
1 5
<210> 3033
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3033
Lys Ser Gln Pro Pro Pro Pro Gln Pro Ala Arg
1 5 10
<210> 3034
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3034
Lys Ser Ser Ile Ile Ile Arg
1 5
<210> 3035
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3035
Lys Ser Thr Val Leu Gln Gln Gln Tyr Asn Arg
1 5 10
<210> 3036
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3036
Lys Thr Ala Leu Trp Ile Thr Arg
1 5
<210> 3037
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3037
Lys Thr Ala Asn Asp Met Ile His Ala Glu Asn Met Arg
1 5 10
<210> 3038
<211> 30
<212> PRT
<213> Homo sapiens
<400> 3038
Lys Thr Asp Glu Leu Pro Gln Leu Val Thr Leu Pro His Pro Asn Leu
1 5 10 15
His Gly Pro Glu Ile Leu Asp Val Pro Ser Thr Val Gln Lys
20 25 30
<210> 3039
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3039
Lys Thr Lys Pro Tyr Ile Gln Val Asp Ile Gly Gly Gly Gln Thr Lys
1 5 10 15
<210> 3040
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3040
Lys Thr Leu Glu Glu Glu Ala Lys
1 5
<210> 3041
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3041
Lys Thr Leu Leu Ser Asn Leu Glu Glu Ala Lys
1 5 10
<210> 3042
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3042
Lys Thr Leu Gln Ala Leu Glu Phe His Thr Val Pro Phe Gln Leu Leu
1 5 10 15
Ala Arg
<210> 3043
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3043
Lys Thr Gln Ile Phe Leu Pro Met Asn Phe Lys
1 5 10
<210> 3044
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3044
Lys Thr Gln Ile Leu Val Gly Val Asn Lys
1 5 10
<210> 3045
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3045
Lys Thr Ser Leu Glu Asp Phe Tyr Leu Asp Glu Glu Arg
1 5 10
<210> 3046
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3046
Lys Thr Thr Val Ile Leu Pro Leu Ala Pro Phe Val Arg
1 5 10
<210> 3047
<211> 30
<212> PRT
<213> Homo sapiens
<400> 3047
Lys Val Ala Asp Ala Leu Thr Asn Ala Val Ala His Val Asp Asp Met
1 5 10 15
Pro Asn Ala Leu Ser Ala Leu Ser Asp Leu His Ala His Lys
20 25 30
<210> 3048
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3048
Lys Val Ala Gln Glu Leu Glu Glu Lys
1 5
<210> 3049
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3049
Lys Val Ala Val Phe Phe Ser Asn Thr Pro Thr Arg
1 5 10
<210> 3050
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3050
Lys Val Ala Val Leu Val Met Gly Arg
1 5
<210> 3051
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3051
Lys Val Glu Phe Val Leu Lys
1 5
<210> 3052
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3052
Lys Val Glu Gly Thr Ala Phe Val Ile Phe Gly Ile Gln Asp Gly Glu
1 5 10 15
Gln Arg
<210> 3053
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3053
Lys Val Glu Ser Glu Leu Ile Lys Pro Ile Asn Pro Arg
1 5 10
<210> 3054
<211> 29
<212> PRT
<213> Homo sapiens
<400> 3054
Lys Val Glu Thr Asn Met Ala Phe Ser Pro Phe Ser Ile Ala Ser Leu
1 5 10 15
Leu Thr Gln Val Leu Leu Gly Ala Gly Glu Asn Thr Lys
20 25
<210> 3055
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3055
Lys Val Phe Ala Ser Leu Pro Gln Val Glu Arg
1 5 10
<210> 3056
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3056
Lys Val Phe Ser Gly Asp Gly Lys
1 5
<210> 3057
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3057
Lys Val Gly Ser Gln Tyr Arg
1 5
<210> 3058
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3058
Lys Val Gly Thr Ala Ser Glu Asn Val Tyr Val Asn Thr Ala His Leu
1 5 10 15
Lys
<210> 3059
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3059
Lys Val His Val Ile Phe Asn Tyr Lys
1 5
<210> 3060
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3060
Lys Val Ile Glu Lys
1 5
<210> 3061
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3061
Lys Val Ile Val Ile Pro Val Gly Ile Gly Pro His Ala Asn Leu Lys
1 5 10 15
<210> 3062
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3062
Lys Val Leu Glu Lys
1 5
<210> 3063
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3063
Lys Val Leu Gly Ala Phe Ser Asp Gly Leu Ala His Leu Asp Asn Leu
1 5 10 15
Lys
<210> 3064
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3064
Lys Val Leu Leu Asp Gly Val Gln Asn Pro Arg
1 5 10
<210> 3065
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3065
Lys Val Met Tyr Thr Gln Tyr Glu Asp Glu Ser Phe Thr Lys
1 5 10
<210> 3066
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3066
Lys Val Asn Leu Gly Val Gly Ala Tyr Arg
1 5 10
<210> 3067
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3067
Lys Val Pro Gln Val Ser Thr Pro Thr Leu Val Glu Val Ser Arg
1 5 10 15
<210> 3068
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3068
Lys Val Gln Tyr Ala Pro Glu Arg Pro Gly Pro Gln Pro Thr Ala Glu
1 5 10 15
Thr Thr Arg
<210> 3069
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3069
Lys Val Ser Pro His Ser Gly Val Val Ala Leu Thr Lys Pro Val Pro
1 5 10 15
Glu Pro Arg
<210> 3070
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3070
Lys Val Thr Cys Thr Asn Ala Glu Leu Val Lys
1 5 10
<210> 3071
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3071
Lys Val Thr His Ala Val Val Thr Val Pro Ala Tyr Phe Asn Asp Ala
1 5 10 15
Gln Arg
<210> 3072
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3072
Lys Val Thr Ser Glu Asp Leu Lys
1 5
<210> 3073
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3073
Lys Val Val Ala Thr Thr Gln Met Gln Ala Ala Asp Ala Arg
1 5 10
<210> 3074
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3074
Lys Val Val Thr Val Leu Val Arg
1 5
<210> 3075
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3075
Lys Val Tyr Leu Ser Glu Cys Lys
1 5
<210> 3076
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3076
Lys Trp Asp Pro Tyr Lys
1 5
<210> 3077
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3077
Lys Trp Gly Gln Leu Leu Leu Pro Ser Leu Leu Asp Leu His Leu Pro
1 5 10 15
Arg
<210> 3078
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3078
Lys Trp Leu Thr Phe Ser Leu Gly Lys
1 5
<210> 3079
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3079
Lys Trp Gln Glu Glu Met Glu Leu Tyr Arg
1 5 10
<210> 3080
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3080
Lys Trp Trp Thr Gln Ala Gln Ala His Asp Leu Val Ile Lys
1 5 10
<210> 3081
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3081
Lys Tyr Ala Phe Glu Leu Lys
1 5
<210> 3082
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3082
Lys Tyr Glu Asp Glu Ile Asn Lys
1 5
<210> 3083
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3083
Lys Tyr Glu Glu Val Ala Arg
1 5
<210> 3084
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3084
Lys Tyr Phe Ile Asp Phe Val Ala Arg
1 5
<210> 3085
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3085
Lys Tyr Leu Tyr Glu Ile Ala Arg
1 5
<210> 3086
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3086
Lys Tyr Asn Glu Leu Leu Lys
1 5
<210> 3087
<211> 23
<212> PRT
<213> Homo sapiens
<400> 3087
Lys Tyr Asn Pro Ile Pro Ser Val Gln Leu Met Gly Asn Gly Phe His
1 5 10 15
Phe Leu Ala Gly Glu Pro Arg
20
<210> 3088
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3088
Lys Tyr Asn Ser Gln Asn Gln Ser Asn Asn Gln Phe Val Leu Tyr Arg
1 5 10 15
<210> 3089
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3089
Lys Tyr Pro Val Ala His Phe Ile Asp Gln Thr Leu Lys
1 5 10
<210> 3090
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3090
Lys Tyr Gln Pro Asn Ile Asp Val Gln Glu Ser Ile His Phe Leu Glu
1 5 10 15
Ser Glu Phe Ser Arg
20
<210> 3091
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3091
Lys Tyr Ser Gln Phe Ile Asn Phe Pro Ile Tyr Val Trp Ser Ser Lys
1 5 10 15
<210> 3092
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3092
Lys Tyr Thr Pro Glu Gln Val Ala Met Ala Thr Val Thr Ala Leu His
1 5 10 15
Arg
<210> 3093
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3093
Lys Tyr Thr Tyr Asn Tyr Glu Ala Glu Ser Ser Ser Gly Val Pro Gly
1 5 10 15
Thr Ala Asp Ser Arg
20
<210> 3094
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3094
Lys Tyr Val Leu Pro Asn Phe Glu Val Lys
1 5 10
<210> 3095
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3095
Lys Tyr Trp Asn Asp Cys Glu Pro Pro Asp Ser Arg
1 5 10
<210> 3096
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3096
Leu Ala Ala Ala Leu Gly Ile Arg
1 5
<210> 3097
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3097
Leu Ala Ala Ala Val Ser Asn Phe Gly Tyr Asp Leu Tyr Arg
1 5 10
<210> 3098
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3098
Leu Ala Ala Asp Asp Phe Arg
1 5
<210> 3099
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3099
Leu Ala Ala Phe Gly Gln Leu His Lys
1 5
<210> 3100
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3100
Leu Ala Ala Leu Asn Pro Glu Ser Asn Thr Ala Gly Leu Asp Ile Phe
1 5 10 15
Ala Lys
<210> 3101
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3101
Leu Ala Ala Tyr Leu Met Leu Met Arg
1 5
<210> 3102
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3102
Leu Ala Asp Asp Leu Tyr Arg
1 5
<210> 3103
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3103
Leu Ala Asp Gly Gly Ala Thr Asn Gln Gly Arg
1 5 10
<210> 3104
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3104
Leu Ala Asp Val Val Lys
1 5
<210> 3105
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3105
Leu Ala Glu Gly Phe Pro Leu Pro Leu Leu Lys
1 5 10
<210> 3106
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3106
Leu Ala Glu Gly Phe Pro Leu Pro Leu Leu Lys Arg
1 5 10
<210> 3107
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3107
Leu Ala Glu Tyr His Ala Lys
1 5
<210> 3108
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3108
Leu Ala Gly Ala Pro Ser Glu Asp Pro Gln Phe Pro Lys
1 5 10
<210> 3109
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3109
Leu Ala Gly Ile Ile Asn Phe Gln Arg Pro Lys
1 5 10
<210> 3110
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3110
Leu Ala Gly Leu Asp Ala Gly Leu His Gln Leu His Val Arg
1 5 10
<210> 3111
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3111
Leu Ala Gly Tyr Leu His Thr Leu Val Gln Asn Leu Val Asn Asn Gly
1 5 10 15
Tyr Val Arg
<210> 3112
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3112
Leu Ala Ile Leu Gly Ile His Asn Glu Val Ser Lys
1 5 10
<210> 3113
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3113
Leu Ala Ile Pro Glu Gly Lys
1 5
<210> 3114
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3114
Leu Ala Lys His Leu Glu Val Asp Val Trp Val Ile Glu Pro Gln Gly
1 5 10 15
Leu Arg
<210> 3115
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3115
Leu Ala Lys Thr Tyr Glu Thr Thr Leu Glu Lys
1 5 10
<210> 3116
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3116
Leu Ala Leu Asp Ile Glu Ile Ala Thr Tyr Arg
1 5 10
<210> 3117
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3117
Leu Ala Leu Asp Leu Glu Ile Ala Thr Tyr Arg
1 5 10
<210> 3118
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3118
Leu Ala Leu Asp Asn Gly Gly Leu Ala Arg
1 5 10
<210> 3119
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3119
Leu Ala Leu Glu Thr Ala Leu Met Tyr Gly Ala Lys
1 5 10
<210> 3120
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3120
Leu Ala Leu Asn Pro Arg
1 5
<210> 3121
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3121
Leu Ala Leu Trp Gly Glu His Thr Gly Gln Leu Tyr Ser Lys
1 5 10
<210> 3122
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3122
Leu Ala Asn Asn Thr Thr Val Lys
1 5
<210> 3123
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3123
Leu Ala Asn Val Met Met Gly Pro Tyr Arg Gln Asp Leu Leu Ala Lys
1 5 10 15
<210> 3124
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3124
Leu Ala Pro Gly Lys
1 5
<210> 3125
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3125
Leu Ala Pro Leu Ala Glu Asp Val Arg
1 5
<210> 3126
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3126
Leu Ala Gln Ala Asn Gly Trp Gly Val Met Val Ser His Arg
1 5 10
<210> 3127
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3127
Leu Ala Gln Gly Leu Thr His Leu Gly Lys
1 5 10
<210> 3128
<211> 26
<212> PRT
<213> Homo sapiens
<400> 3128
Leu Ala Gln Lys Val Pro Thr Ala Asp Leu Glu Asp Val Leu Pro Leu
1 5 10 15
Ala Glu Asp Ile Thr Asn Ile Leu Ser Lys
20 25
<210> 3129
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3129
Leu Ala Gln Val Ala Lys Ala Val Thr Gln Ala Leu Asn Arg
1 5 10
<210> 3130
<211> 22
<212> PRT
<213> Homo sapiens
<400> 3130
Leu Ala Ser Glu Ala Lys Pro Ala Ala Val Ala Ala Glu Asn Glu Glu
1 5 10 15
Ile Gly Ser His Ile Lys
20
<210> 3131
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3131
Leu Ala Ser His Leu Arg
1 5
<210> 3132
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3132
Leu Ala Ser Leu Phe Pro Ala Leu Phe Ser Arg
1 5 10
<210> 3133
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3133
Leu Ala Ser Pro Gly Phe Pro Gly Glu Tyr Ala Asn Asp Gln Glu Arg
1 5 10 15
Arg
<210> 3134
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3134
Leu Ala Ser Val Ser Val Ser Arg
1 5
<210> 3135
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3135
Leu Ala Ser Tyr Leu Asp Lys
1 5
<210> 3136
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3136
Leu Ala Thr Ala Leu Gln Lys
1 5
<210> 3137
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3137
Leu Ala Thr Ala Leu Ser Leu Ser Asn Lys
1 5 10
<210> 3138
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3138
Leu Ala Val Thr Thr His Gly Leu Pro Cys Leu Ala Trp Ala Ser Ala
1 5 10 15
Gln Ala Lys
<210> 3139
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3139
Leu Ala Val Tyr Gln Ala Gly Ala Arg
1 5
<210> 3140
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3140
Leu Cys Asp Asn Leu Ser Thr Lys
1 5
<210> 3141
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3141
Leu Cys Phe Phe Tyr Asn Lys Lys
1 5
<210> 3142
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3142
Leu Cys Met Ala Ala Leu Lys
1 5
<210> 3143
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3143
Leu Cys Gln Asp Leu Gly Pro Gly Ala Phe Arg
1 5 10
<210> 3144
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3144
Leu Cys Ser Gly Phe Val Arg
1 5
<210> 3145
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3145
Leu Cys Thr Pro Leu Leu Pro Lys
1 5
<210> 3146
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3146
Leu Cys Thr Val Ala Thr Leu Arg
1 5
<210> 3147
<211> 22
<212> PRT
<213> Homo sapiens
<400> 3147
Leu Asp Ala His Lys Val Leu Ser Ala Leu Gln Ala Val Gln Gly Leu
1 5 10 15
Leu Val Ala Gln Gly Arg
20
<210> 3148
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3148
Leu Asp Ala Gln Ala Ser Phe Leu Pro Lys
1 5 10
<210> 3149
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3149
Leu Asp Asp Asp Leu Glu His Gln Gly Gly His Val Leu Asp His Gly
1 5 10 15
His Lys
<210> 3150
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3150
Leu Asp Asp Gly Arg Trp His Gln Val Glu Val Lys
1 5 10
<210> 3151
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3151
Leu Asp Glu Ile Leu Lys
1 5
<210> 3152
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3152
Leu Asp Glu Leu Arg Asp Glu Gly Lys
1 5
<210> 3153
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3153
Leu Asp Glu Val Lys Glu Gln Val Ala Glu Val Arg
1 5 10
<210> 3154
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3154
Leu Asp Phe His Phe Ser Ser Asp Arg
1 5
<210> 3155
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3155
Leu Asp Phe Leu Arg Pro Tyr Thr Val Pro Asn Lys Lys
1 5 10
<210> 3156
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3156
Leu Asp Phe Ser Ser Gln Ala Asp Leu Arg
1 5 10
<210> 3157
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3157
Leu Asp Phe Ser Ser Gln Ala Asp Leu Arg Asn Glu Ile Lys
1 5 10
<210> 3158
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3158
Leu Asp Gly Lys Phe Ser Val Val Tyr Ala Lys
1 5 10
<210> 3159
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3159
Leu Asp Gly Gln Phe Arg
1 5
<210> 3160
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3160
Leu Asp Gly Ser Val Asp Phe Lys
1 5
<210> 3161
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3161
Leu Asp Gly Ser Val Asp Phe Lys Lys
1 5
<210> 3162
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3162
Leu Asp His Leu Ala Glu Lys
1 5
<210> 3163
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3163
Leu Asp Ile Ala Gly Arg
1 5
<210> 3164
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3164
Leu Asp Lys Met Val Thr Lys
1 5
<210> 3165
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3165
Leu Asp Leu Ala Gly Arg
1 5
<210> 3166
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3166
Leu Asp Leu Leu Glu Asp Arg
1 5
<210> 3167
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3167
Leu Asp Leu Gln Glu Ile Asn Asn Trp Val Gln Ala Gln Met Lys
1 5 10 15
<210> 3168
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3168
Leu Asp Leu Ser Leu Asn Arg Leu Lys
1 5
<210> 3169
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3169
Leu Asp Leu Thr Glu Lys
1 5
<210> 3170
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3170
Leu Asp Leu Thr Glu Lys Asp Tyr Glu Ile Leu Phe Lys
1 5 10
<210> 3171
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3171
Leu Asp Asn Ile Tyr Ser Ser Asp Lys
1 5
<210> 3172
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3172
Leu Asp Asn Ile Tyr Ser Ser Asp Lys Phe Tyr Lys
1 5 10
<210> 3173
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3173
Leu Asp Pro His Asn His Val Leu Tyr Ser Asn Arg
1 5 10
<210> 3174
<211> 36
<212> PRT
<213> Homo sapiens
<400> 3174
Leu Asp Gln Ile Glu Ser Val Ile Thr Ala Thr Ser Ala Asn Thr Gln
1 5 10 15
Leu Val Leu Glu Thr Leu Ala Gln Met Asp Asp Leu Gln Asp Phe Leu
20 25 30
Ser Lys Asp Lys
35
<210> 3175
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3175
Leu Asp Gln Leu Glu Lys
1 5
<210> 3176
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3176
Leu Asp Gln Leu Ile Tyr Ile Pro Leu Pro Asp Glu Lys
1 5 10
<210> 3177
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3177
Leu Asp Arg Glu Asn Ile Ser Glu Tyr His Leu Thr Ala Val Ile Val
1 5 10 15
Asp Lys
<210> 3178
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3178
Leu Asp Ser Glu Leu Lys
1 5
<210> 3179
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3179
Leu Asp Thr Glu Asp Lys
1 5
<210> 3180
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3180
Leu Asp Thr Glu Asp Lys Leu Arg
1 5
<210> 3181
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3181
Leu Asp Thr Leu Ala Gln Glu Val Ala Leu Leu Lys
1 5 10
<210> 3182
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3182
Leu Asp Val Asp Trp Arg
1 5
<210> 3183
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3183
Leu Asp Val Asp Trp Arg Glu Leu Asn Glu Leu Gly Ser Lys
1 5 10
<210> 3184
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3184
Leu Asp Val Pro Val Trp Asp Val Glu Ala Thr Leu Asn Phe Leu Lys
1 5 10 15
<210> 3185
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3185
Leu Asp Val Thr Thr Ser Ile Gly Arg
1 5
<210> 3186
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3186
Leu Asp Val Thr Thr Ser Ile Gly Arg Arg
1 5 10
<210> 3187
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3187
Leu Glu Ala Ile Lys
1 5
<210> 3188
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3188
Leu Glu Ala Leu Lys
1 5
<210> 3189
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3189
Leu Glu Ala Leu Lys Glu Asn Gly Gly Ala Arg
1 5 10
<210> 3190
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3190
Leu Glu Ala Val Ser His Thr Ser Asp Met His Arg
1 5 10
<210> 3191
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3191
Leu Glu Asp Phe Arg Asp Tyr Arg
1 5
<210> 3192
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3192
Leu Glu Asp Met Glu Gln Ala Leu Ser Pro Ser Val Phe Lys
1 5 10
<210> 3193
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3193
Leu Glu Asp Ser Val Thr Tyr His Cys Ser Arg
1 5 10
<210> 3194
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3194
Leu Glu Asp Thr Pro Lys
1 5
<210> 3195
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3195
Leu Glu Glu Ala Glu Lys
1 5
<210> 3196
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3196
Leu Glu Glu His Leu Glu Gly Ile Val Asn Ile Phe His Gln Tyr Ser
1 5 10 15
Val Arg
<210> 3197
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3197
Leu Glu Glu Gln Ala Gln Gln Ile Arg
1 5
<210> 3198
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3198
Leu Glu Glu Val Leu Thr Asn Lys Lys
1 5
<210> 3199
<211> 24
<212> PRT
<213> Homo sapiens
<400> 3199
Leu Glu Gly Ser Ala Pro Thr Asp Val Leu Asp Ser Leu Thr Thr Ile
1 5 10 15
Pro Glu Leu Lys Asp His Leu Arg
20
<210> 3200
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3200
Leu Glu Gly Ser Ile Asn Asp Ile Lys
1 5
<210> 3201
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3201
Leu Glu His Glu Tyr Ile His Asn Phe Lys
1 5 10
<210> 3202
<211> 31
<212> PRT
<213> Homo sapiens
<400> 3202
Leu Glu Ile Gly Gln Asp Leu Ile Gln Val Ala Val Ala Gln Tyr Ala
1 5 10 15
Asp Thr Val Arg Pro Glu Phe Tyr Phe Asn Thr His Pro Thr Lys
20 25 30
<210> 3203
<211> 20
<212> PRT
<213> Homo sapiens
<400> 3203
Leu Glu Ile Gln Ser Gln Val Asp Ser Gln His Val Gly His Ser Val
1 5 10 15
Leu Thr Ala Lys
20
<210> 3204
<211> 24
<212> PRT
<213> Homo sapiens
<400> 3204
Leu Glu Leu Glu Leu Arg Pro Thr Gly Glu Ile Glu Gln Tyr Ser Val
1 5 10 15
Ser Ala Thr Tyr Glu Leu Gln Arg
20
<210> 3205
<211> 27
<212> PRT
<213> Homo sapiens
<400> 3205
Leu Glu Leu Glu Leu Arg Pro Thr Gly Glu Ile Glu Gln Tyr Ser Val
1 5 10 15
Ser Ala Thr Tyr Glu Leu Gln Arg Glu Asp Arg
20 25
<210> 3206
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3206
Leu Glu Leu His Leu Pro Lys
1 5
<210> 3207
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3207
Leu Glu Leu His Val Asp Gly Pro Pro Pro Arg Pro Gln Leu Arg
1 5 10 15
<210> 3208
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3208
Leu Glu Leu Leu Ser Leu Ser Lys
1 5
<210> 3209
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3209
Leu Glu Leu Gln Glu Lys
1 5
<210> 3210
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3210
Leu Glu Leu Ser Val Asp Gly Ala Lys
1 5
<210> 3211
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3211
Leu Glu Leu Trp Ile Asn Leu Arg
1 5
<210> 3212
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3212
Leu Glu Met Ser Lys
1 5
<210> 3213
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3213
Leu Glu Met Ser Lys Phe Gln Pro Thr Leu Leu Thr Leu Pro Arg
1 5 10 15
<210> 3214
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3214
Leu Glu Asn Glu Ile Gln Thr Tyr Arg
1 5
<210> 3215
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3215
Leu Glu Pro Gly Lys
1 5
<210> 3216
<211> 40
<212> PRT
<213> Homo sapiens
<400> 3216
Leu Glu Pro Gly Lys Glu Tyr Leu Ile Met Gly Leu Asp Gly Ala Thr
1 5 10 15
Tyr Asp Leu Glu Gly His Pro Gln Tyr Leu Leu Asp Ser Asn Ser Trp
20 25 30
Ile Glu Glu Met Pro Ser Glu Arg
35 40
<210> 3217
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3217
Leu Glu Pro Gly Gln Gln Glu Glu Tyr Tyr Arg
1 5 10
<210> 3218
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3218
Leu Glu Pro Gly Gln Gln Glu Glu Tyr Tyr Arg Lys
1 5 10
<210> 3219
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3219
Leu Glu Pro Ile Lys
1 5
<210> 3220
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3220
Leu Glu Pro Leu Lys
1 5
<210> 3221
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3221
Leu Glu Pro Leu Lys Leu His Val Ala Gly Asn Leu Lys
1 5 10
<210> 3222
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3222
Leu Glu Pro Tyr Ala Asp Gln Leu Arg
1 5
<210> 3223
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3223
Leu Glu Gln Glu Ile Ala Thr Tyr Arg
1 5
<210> 3224
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3224
Leu Glu Gln Phe Val Ser Ile Leu Met Ala Ser Ile Pro Leu Pro Asp
1 5 10 15
Lys
<210> 3225
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3225
Leu Glu Gln Gly Glu Asn Val Phe Leu Gln Ala Thr Asp Lys
1 5 10
<210> 3226
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3226
Leu Glu Arg Glu Leu Lys
1 5
<210> 3227
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3227
Leu Glu Arg Leu Ala Ala Lys
1 5
<210> 3228
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3228
Leu Glu Ser Asp Val Ser Ala Gln Met Glu Tyr Cys Arg
1 5 10
<210> 3229
<211> 30
<212> PRT
<213> Homo sapiens
<400> 3229
Leu Glu Ser Glu Glu Thr Met Val Leu Glu Ala His Asp Ala Gln Gly
1 5 10 15
Asp Val Pro Val Thr Val Thr Val His Asp Phe Pro Gly Lys
20 25 30
<210> 3230
<211> 31
<212> PRT
<213> Homo sapiens
<400> 3230
Leu Glu Ser Glu Glu Thr Met Val Leu Glu Ala His Asp Ala Gln Gly
1 5 10 15
Asp Val Pro Val Thr Val Thr Val His Asp Phe Pro Gly Lys Lys
20 25 30
<210> 3231
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3231
Leu Glu Thr Val Leu Glu Ser Ile Gln Lys
1 5 10
<210> 3232
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3232
Leu Glu Val Asp Ile Asp Ile Lys
1 5
<210> 3233
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3233
Leu Glu Val His Tyr His Asn Pro Leu Val Ile Glu Gly Arg
1 5 10
<210> 3234
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3234
Leu Glu Val Ile Lys
1 5
<210> 3235
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3235
Leu Glu Val Leu His Lys
1 5
<210> 3236
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3236
Leu Glu Val Leu Lys
1 5
<210> 3237
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3237
Leu Glu Val Leu Lys Arg
1 5
<210> 3238
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3238
Leu Glu Val Leu Asn Phe Asp Phe Gln Ala Asn Ala Gln Leu Ser Asn
1 5 10 15
Pro Lys
<210> 3239
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3239
Leu Glu Val Gln Ile Lys
1 5
<210> 3240
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3240
Leu Glu Tyr Leu Leu Leu Ser Arg
1 5
<210> 3241
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3241
Leu Glu Tyr Pro Thr Cys Ala Lys
1 5
<210> 3242
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3242
Leu Phe Ala Phe Val Arg
1 5
<210> 3243
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3243
Leu Phe Ala Gly Leu Val His Val Lys
1 5
<210> 3244
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3244
Leu Phe Ala Val Phe Glu Arg Pro Gln Gly Ser Pro Ala Ala Arg
1 5 10 15
<210> 3245
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3245
Leu Phe Ala Tyr Pro Asp Thr His Arg
1 5
<210> 3246
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3246
Leu Phe Asp Glu Ile Asn Pro Glu Thr Lys
1 5 10
<210> 3247
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3247
Leu Phe Asp Ser Asp Pro Ile Thr Val Thr Val Pro Val Glu Val Ser
1 5 10 15
Arg Lys
<210> 3248
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3248
Leu Phe Glu His Pro Leu Tyr Arg
1 5
<210> 3249
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3249
Leu Phe Glu Thr Lys
1 5
<210> 3250
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3250
Leu Phe Glu Thr Lys Ile Thr Gln Val Leu His Phe Thr Lys
1 5 10
<210> 3251
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3251
Leu Phe Phe Gly Pro Gln His Arg Pro Val Ile Leu Arg
1 5 10
<210> 3252
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3252
Leu Phe Phe Leu Gln Val Lys
1 5
<210> 3253
<211> 31
<212> PRT
<213> Homo sapiens
<400> 3253
Leu Phe Gly Glu Val Thr Ser Pro Leu Phe Pro Lys Pro Tyr Pro Asn
1 5 10 15
Asn Phe Glu Thr Thr Thr Val Ile Thr Val Pro Thr Gly Tyr Arg
20 25 30
<210> 3254
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3254
Leu Phe Gly Gly Asn Phe Ala His Gln Ala Ser Val Ala Arg
1 5 10
<210> 3255
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3255
Leu Phe Gly Pro Asp Leu Lys
1 5
<210> 3256
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3256
Leu Phe His Thr Asn Phe Tyr Asp Thr Val Gly Thr Ile Gln Leu Ile
1 5 10 15
Asn Asp His Val Lys
20
<210> 3257
<211> 22
<212> PRT
<213> Homo sapiens
<400> 3257
Leu Phe His Thr Asn Phe Tyr Asp Thr Val Gly Thr Ile Gln Leu Ile
1 5 10 15
Asn Asp His Val Lys Lys
20
<210> 3258
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3258
Leu Phe Ile Asn Val Ala Pro His Ala Arg
1 5 10
<210> 3259
<211> 23
<212> PRT
<213> Homo sapiens
<400> 3259
Leu Phe Leu Glu Ala Leu Val Asp Ser Val Ala Gln Gly Ile Pro Phe
1 5 10 15
Gln Gln His Gln Phe Asp Lys
20
<210> 3260
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3260
Leu Phe Leu Glu Glu Thr Lys
1 5
<210> 3261
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3261
Leu Phe Leu Glu Pro Thr Gln Ala Asp Ile Ala Leu Leu Lys
1 5 10
<210> 3262
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3262
Leu Phe Leu Glu Pro Thr Arg
1 5
<210> 3263
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3263
Leu Phe Leu Glu Pro Thr Arg Lys
1 5
<210> 3264
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3264
Leu Phe Leu Leu Thr Val His Lys
1 5
<210> 3265
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3265
Leu Phe Pro Leu Pro Gly Arg
1 5
<210> 3266
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3266
Leu Phe Pro Asn Phe Leu Lys
1 5
<210> 3267
<211> 24
<212> PRT
<213> Homo sapiens
<400> 3267
Leu Phe Gln Phe His Phe His Trp Gly Ser Thr Asn Glu His Gly Ser
1 5 10 15
Glu His Thr Val Asp Gly Val Lys
20
<210> 3268
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3268
Leu Phe Gln Gly Leu Gly Lys
1 5
<210> 3269
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3269
Leu Phe Gln Gly Leu Gly Lys Leu Glu Tyr Leu Leu Leu Ser Arg
1 5 10 15
<210> 3270
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3270
Leu Phe Gln Pro Leu Thr His Leu Lys
1 5
<210> 3271
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3271
Leu Phe Gln Val Glu Tyr Ala Ile Glu Ala Ile Lys
1 5 10
<210> 3272
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3272
Leu Phe Gln Val Lys
1 5
<210> 3273
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3273
Leu Phe Ser Leu Lys Pro Thr Ser Gly Pro Val Leu Thr Val Thr Leu
1 5 10 15
Phe Gly Arg
<210> 3274
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3274
Leu Phe Ser Val Lys
1 5
<210> 3275
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3275
Leu Phe Thr Asn Phe His Arg
1 5
<210> 3276
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3276
Leu Phe Trp Glu Pro Met Lys
1 5
<210> 3277
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3277
Leu Phe Tyr Ile Lys
1 5
<210> 3278
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3278
Leu Phe Tyr Leu Lys
1 5
<210> 3279
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3279
Leu Gly Ala Thr Ala Glu Lys
1 5
<210> 3280
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3280
Leu Gly Asp Asp Leu Leu Gln Cys His Pro Ala Val Lys
1 5 10
<210> 3281
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3281
Leu Gly Glu Val Asn Thr Tyr Ala Gly Asp Leu Gln Lys
1 5 10
<210> 3282
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3282
Leu Gly Glu Tyr Asp Leu Arg
1 5
<210> 3283
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3283
Leu Gly Phe Thr Asp Leu Phe Ser Lys
1 5
<210> 3284
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3284
Leu Gly Gly Ser Ala Val Ile Ser Leu Glu Gly Lys Pro Leu
1 5 10
<210> 3285
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3285
Leu Gly Gly Ser Val Pro His Leu Arg
1 5
<210> 3286
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3286
Leu Gly Gly Val Lys
1 5
<210> 3287
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3287
Leu Gly His Gly Val Asn Asn Ala Ala Gly Gln Val Gly Lys
1 5 10
<210> 3288
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3288
Leu Gly His Leu Leu His Ile Arg
1 5
<210> 3289
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3289
Leu Gly His Leu Leu His Ile Arg Asp Glu Lys
1 5 10
<210> 3290
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3290
Leu Gly His Pro Asp Thr Leu Asn Gln Gly Glu Phe Lys
1 5 10
<210> 3291
<211> 25
<212> PRT
<213> Homo sapiens
<400> 3291
Leu Gly His Pro Glu Ala Leu Ser Ala Gly Thr Gly Ser Pro Gln Pro
1 5 10 15
Pro Ser Phe Thr Tyr Ala Gln Gln Arg
20 25
<210> 3292
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3292
Leu Gly Lys Asp Ala Val Glu Asp Leu Glu Ser Val Gly Lys
1 5 10
<210> 3293
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3293
Leu Gly Met Phe Asn Ile Gln His Cys Lys
1 5 10
<210> 3294
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3294
Leu Gly Met Phe Asn Ile Gln His Cys Lys Lys
1 5 10
<210> 3295
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3295
Leu Gly Asn Phe Pro Trp Gln Ala Phe Thr Ser Ile His Gly Arg
1 5 10 15
<210> 3296
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3296
Leu Gly Asn Asn Pro Val Ser Lys
1 5
<210> 3297
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3297
Leu Gly Asn Gln Glu Pro Gly Gly Gln Thr Ala Leu Lys
1 5 10
<210> 3298
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3298
Leu Gly Pro Glu Ala Ala Val Gly Arg
1 5
<210> 3299
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3299
Leu Gly Pro His Ala Gly Asp Val Glu Gly His Leu Ser Phe Leu Glu
1 5 10 15
Lys
<210> 3300
<211> 25
<212> PRT
<213> Homo sapiens
<400> 3300
Leu Gly Pro Leu Ser Ala Glu Gly Thr Thr Gly Leu Ala Pro Ala Gly
1 5 10 15
Gln Thr Ser Glu Glu Ser Arg Pro Arg
20 25
<210> 3301
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3301
Leu Gly Pro Leu Val Glu Gln Gly Arg
1 5
<210> 3302
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3302
Leu Gly Pro Asn Tyr Leu His Ile Pro Val Asn Cys Pro Tyr Arg
1 5 10 15
<210> 3303
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3303
Leu Gly Gln Ser Leu Asp Cys Asn Ala Glu Val Tyr Val Val Pro Trp
1 5 10 15
Glu Lys
<210> 3304
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3304
Leu Gly Gln Tyr Ala Ser Pro Thr Ala Lys
1 5 10
<210> 3305
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3305
Leu Gly Gln Tyr Ala Ser Pro Thr Ala Lys Arg
1 5 10
<210> 3306
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3306
Leu Gly Ser Gly Leu Gln Gly Glu Val Lys
1 5 10
<210> 3307
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3307
Leu Gly Ser Leu Gly Ala Ala Cys Glu Gln Thr Gln Thr Glu Gly Ala
1 5 10 15
Lys
<210> 3308
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3308
Leu Gly Ser Leu His Pro His Thr Pro Tyr His Ile Arg
1 5 10
<210> 3309
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3309
Leu Gly Ser Tyr Glu His Arg
1 5
<210> 3310
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3310
Leu Gly Val Asn Val Thr Trp Lys
1 5
<210> 3311
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3311
Leu Gly Val Arg Pro Ser Gln Gly Gly Glu Ala Pro Arg
1 5 10
<210> 3312
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3312
Leu Gly Val Tyr Glu Leu Leu Leu Lys
1 5
<210> 3313
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3313
Leu Gly Val Tyr Glu Leu Leu Leu Lys Val Arg Pro Gln Gln Leu Val
1 5 10 15
Lys
<210> 3314
<211> 35
<212> PRT
<213> Homo sapiens
<400> 3314
Leu Gly Trp Ala Met Thr Ser Ala Asp Leu Asn Gln Asp Gly His Gly
1 5 10 15
Asp Leu Val Val Gly Ala Pro Gly Tyr Ser Arg Pro Gly His Ile His
20 25 30
Ile Gly Arg
35
<210> 3315
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3315
Leu His Ala Pro Leu Leu Thr Arg
1 5
<210> 3316
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3316
Leu His Ala Val Pro Asn Leu Arg
1 5
<210> 3317
<211> 37
<212> PRT
<213> Homo sapiens
<400> 3317
Leu His Asp Asn Gln Asn Gly Trp Ser Gly Asp Ser Ala Pro Val Glu
1 5 10 15
Leu Ile Leu Ser Asp Glu Thr Leu Pro Ala Pro Glu Phe Ser Pro Glu
20 25 30
Pro Glu Ser Gly Arg
35
<210> 3318
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3318
Leu His Glu Ala Phe Ser Pro Val Ser Tyr Gln His Asp Leu Ala Leu
1 5 10 15
Leu Arg
<210> 3319
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3319
Leu His Glu Leu Gln Glu Lys
1 5
<210> 3320
<211> 20
<212> PRT
<213> Homo sapiens
<400> 3320
Leu His Phe Phe Met Pro Gly Phe Ala Pro Leu Thr Ala Gln Gly Ser
1 5 10 15
Gln Gln Tyr Arg
20
<210> 3321
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3321
Leu His Phe Phe Met Pro Gly Phe Ala Pro Leu Thr Ser Arg
1 5 10
<210> 3322
<211> 25
<212> PRT
<213> Homo sapiens
<400> 3322
Leu His His Val Ser Ser Leu Ala Trp Leu Asp Glu His Thr Leu Val
1 5 10 15
Thr Thr Ser His Asp Ala Ser Val Lys
20 25
<210> 3323
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3323
Leu His Ile Asp Asp Met Glu Phe Glu Pro Lys
1 5 10
<210> 3324
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3324
Leu His Ile Asp Glu Met Asp Ser Val Pro Thr Val Arg
1 5 10
<210> 3325
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3325
Leu His Ile Leu Leu Gln Asn Gly Lys
1 5
<210> 3326
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3326
Leu His Ile Met Ala Gly Arg
1 5
<210> 3327
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3327
Leu His Ile Val Gln Val Val Cys Lys
1 5
<210> 3328
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3328
Leu His Ile Val Gln Val Val Cys Lys Lys
1 5 10
<210> 3329
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3329
Leu His Lys Pro Gly Val Tyr Thr Arg
1 5
<210> 3330
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3330
Leu His Leu Glu Gly Asn Lys
1 5
<210> 3331
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3331
Leu His Leu Glu Gly Asn Lys Leu Gln Val Leu Gly Lys
1 5 10
<210> 3332
<211> 25
<212> PRT
<213> Homo sapiens
<400> 3332
Leu His Leu Glu Gly Tyr His Gly Thr Ala Gly Asp Ser Met Ser Tyr
1 5 10 15
His Ser Gly Ser Val Phe Ser Ala Arg
20 25
<210> 3333
<211> 26
<212> PRT
<213> Homo sapiens
<400> 3333
Leu His Leu Glu Thr Asp Ser Leu Ala Leu Val Ala Leu Gly Ala Leu
1 5 10 15
Asp Thr Ala Leu Tyr Ala Ala Gly Ser Lys
20 25
<210> 3334
<211> 35
<212> PRT
<213> Homo sapiens
<400> 3334
Leu His Leu Glu Thr Asp Ser Leu Ala Leu Val Ala Leu Gly Ala Leu
1 5 10 15
Asp Thr Ala Leu Tyr Ala Ala Gly Ser Lys Ser His Lys Pro Leu Asn
20 25 30
Met Gly Lys
35
<210> 3335
<211> 28
<212> PRT
<213> Homo sapiens
<400> 3335
Leu His Leu Leu Asn Ile Gly Gly Ser Gln Asp Ile His Val Val His
1 5 10 15
Phe His Gly Gln Thr Leu Leu Glu Asn Gly Asn Lys
20 25
<210> 3336
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3336
Leu His Leu Val Ala Leu Val Gly Thr Gln Gly Arg
1 5 10
<210> 3337
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3337
Leu His Leu Tyr Asn Ser Leu Thr Arg
1 5
<210> 3338
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3338
Leu His Met Leu Gln Ile Ser Tyr Phe Arg
1 5 10
<210> 3339
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3339
Leu His Arg Pro Pro Val Ile Val Leu Gln Arg
1 5 10
<210> 3340
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3340
Leu His Ser Leu His Leu Glu Gly Ser Cys Leu Gly Arg
1 5 10
<210> 3341
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3341
Leu His Thr Asp Asp Glu Leu Asn Trp Leu Asp His Gly Arg
1 5 10
<210> 3342
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3342
Leu His Thr Glu Ala Gln Ile Gln Glu Glu Gly Thr Val Val Glu Leu
1 5 10 15
Thr Gly Arg
<210> 3343
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3343
Leu His Thr Leu Gly Asp Asn Leu Leu Asp Ser Arg
1 5 10
<210> 3344
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3344
Leu His Val Ala Gly Asn Leu Lys
1 5
<210> 3345
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3345
Leu His Val Asp Pro Glu Asn Phe Arg
1 5
<210> 3346
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3346
Leu Ile Ala Leu Ser Ile Asp Ser Val Glu Asp His Leu Ala Trp Ser
1 5 10 15
Lys
<210> 3347
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3347
Leu Ile Ala Leu Thr Leu Leu Gly Met Gly Leu Ala Leu Phe Arg
1 5 10 15
<210> 3348
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3348
Leu Ile Ala Asn Thr Leu Cys Asn Ser Arg
1 5 10
<210> 3349
<211> 20
<212> PRT
<213> Homo sapiens
<400> 3349
Leu Ile Asp Gln Tyr Gly Thr His Tyr Leu Gln Ser Gly Ser Leu Gly
1 5 10 15
Gly Glu Tyr Arg
20
<210> 3350
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3350
Leu Ile Asp Val Ile Ser Met Tyr Arg
1 5
<210> 3351
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3351
Leu Ile Glu Asn Gly Tyr Phe His Pro Val Lys
1 5 10
<210> 3352
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3352
Leu Ile Phe Lys Lys
1 5
<210> 3353
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3353
Leu Ile Gly Asp Ala Ala Lys
1 5
<210> 3354
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3354
Leu Ile His Phe Ser Ala Lys
1 5
<210> 3355
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3355
Leu Ile His His Gly Val His His Gly Ala Asn Gln Ala Gly Ser Glu
1 5 10 15
Ala Gly Lys
<210> 3356
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3356
Leu Ile Ile Asn Ser Leu Tyr Lys
1 5
<210> 3357
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3357
Leu Ile Leu Asp Phe Leu Asn Ser Lys
1 5
<210> 3358
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3358
Leu Ile Leu Glu Glu Phe Lys
1 5
<210> 3359
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3359
Leu Ile Leu Phe Lys
1 5
<210> 3360
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3360
Leu Ile Leu Phe Arg
1 5
<210> 3361
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3361
Leu Ile Leu Ile Lys
1 5
<210> 3362
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3362
Leu Ile Leu Leu Lys
1 5
<210> 3363
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3363
Leu Ile Leu Leu Arg
1 5
<210> 3364
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3364
Leu Ile Leu Pro His Val Asp Ile Gln Leu Lys
1 5 10
<210> 3365
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3365
Leu Ile Leu Gln Asn His Ile Leu Lys
1 5
<210> 3366
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3366
Leu Ile Leu Val Asp Tyr Ile Leu Phe Lys
1 5 10
<210> 3367
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3367
Leu Ile Leu Trp Arg
1 5
<210> 3368
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3368
Leu Ile Leu Tyr Lys
1 5
<210> 3369
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3369
Leu Ile Leu Tyr Pro Asn Lys
1 5
<210> 3370
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3370
Leu Ile Asn Asp Tyr Val Lys
1 5
<210> 3371
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3371
Leu Ile Asn Asn Ala Ile Lys
1 5
<210> 3372
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3372
Leu Ile Asn Arg Pro Ile Ile Val Phe Arg
1 5 10
<210> 3373
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3373
Leu Ile Pro Phe Val Pro Lys
1 5
<210> 3374
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3374
Leu Ile Gln Asp Ala Val Thr Gly Leu Thr Val Asn Gly Gln Ile Thr
1 5 10 15
Gly Asp Lys
<210> 3375
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3375
Leu Ile Gln Glu Ala Pro Lys Pro Glu Cys Glu Lys
1 5 10
<210> 3376
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3376
Leu Ile Gln Gly Ala Pro Thr Ile Arg
1 5
<210> 3377
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3377
Leu Ile Ser Ala Gln His Asn Gln Ser Lys
1 5 10
<210> 3378
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3378
Leu Ile Ser Leu Arg
1 5
<210> 3379
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3379
Leu Ile Ser Pro Pro Val His Leu Pro Arg
1 5 10
<210> 3380
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3380
Leu Ile Ser Val Asp Thr Glu His Ser Asn Ile Tyr Leu Gln Asn Gly
1 5 10 15
Pro Asp Arg
<210> 3381
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3381
Leu Ile Ser Val Lys
1 5
<210> 3382
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3382
Leu Ile Thr Ala Ser Gly Ser Tyr His Lys
1 5 10
<210> 3383
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3383
Leu Ile Thr Leu Glu Glu Glu Met Thr Lys
1 5 10
<210> 3384
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3384
Leu Ile Val Ala Leu Met Lys Pro Ser Arg
1 5 10
<210> 3385
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3385
Leu Ile Val Ala Met Ser Ser Trp Leu Gln Lys
1 5 10
<210> 3386
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3386
Leu Ile Val Gly Arg
1 5
<210> 3387
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3387
Leu Ile Val His Asn Gly Tyr Cys Asp Gly Arg
1 5 10
<210> 3388
<211> 23
<212> PRT
<213> Homo sapiens
<400> 3388
Leu Ile Val Leu Val Pro Pro Ser Lys Pro Thr Val Asn Ile Pro Ser
1 5 10 15
Ser Ala Thr Ile Gly Asn Arg
20
<210> 3389
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3389
Leu Lys Cys Asp Glu Trp Ser Val Asn Ser Val Gly Lys
1 5 10
<210> 3390
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3390
Leu Lys Asp Asp Glu Val Ala Gln Leu Lys
1 5 10
<210> 3391
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3391
Leu Lys Asp Pro Val Lys
1 5
<210> 3392
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3392
Leu Lys Glu Asp Ala Val Ser Ala Ala Phe Lys
1 5 10
<210> 3393
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3393
Leu Lys Glu Glu Glu Glu Asp Lys
1 5
<210> 3394
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3394
Leu Lys Glu Glu Ile Gly Lys
1 5
<210> 3395
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3395
Leu Lys Glu Glu Leu Gly Lys
1 5
<210> 3396
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3396
Leu Lys Glu Glu Gln Leu Arg
1 5
<210> 3397
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3397
Leu Lys Glu Gly Met Leu Ser Ile Met Ser Tyr Arg
1 5 10
<210> 3398
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3398
Leu Lys Glu Leu Thr Leu Glu Asp Leu Lys
1 5 10
<210> 3399
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3399
Leu Lys Phe Ile Ile Pro Ser Pro Lys
1 5
<210> 3400
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3400
Leu Lys Gly Glu Met Met Asp Leu Gln His Gly Ser Leu Phe Leu Arg
1 5 10 15
<210> 3401
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3401
Leu Lys Gly Pro Leu Leu Asn Lys
1 5
<210> 3402
<211> 23
<212> PRT
<213> Homo sapiens
<400> 3402
Leu Lys His Glu Leu Thr Asp Glu Glu Leu Gln Ser Leu Phe Thr Asn
1 5 10 15
Phe Ala Asn Val Val Asp Lys
20
<210> 3403
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3403
Leu Lys Leu Glu Pro His Glu Gly Leu Leu Leu Arg
1 5 10
<210> 3404
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3404
Leu Lys Leu Ser Ile Leu Tyr Pro Ala Thr Thr Gly Arg
1 5 10
<210> 3405
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3405
Leu Lys Leu Ser Tyr Glu Gly Glu Val Thr Lys
1 5 10
<210> 3406
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3406
Leu Lys Asn Ser Leu Phe Glu Tyr Gln Lys
1 5 10
<210> 3407
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3407
Leu Lys Pro Gly Ala Pro Leu Arg Pro Lys
1 5 10
<210> 3408
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3408
Leu Lys Pro Ile Lys
1 5
<210> 3409
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3409
Leu Lys Pro Lys Pro Ile Asp Val Gln Val Ile Thr His His Met Gln
1 5 10 15
Arg
<210> 3410
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3410
Leu Lys Pro Leu Lys
1 5
<210> 3411
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3411
Leu Lys Pro Leu Leu Asn Thr Met Ile Gln Ser Asn Tyr Asn Arg
1 5 10 15
<210> 3412
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3412
Leu Lys Pro Val Ile Lys
1 5
<210> 3413
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3413
Leu Lys Gln His Ile Glu Ala Ile Asp Val Arg
1 5 10
<210> 3414
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3414
Leu Lys Gln Asn Asp Phe Asn Ser Val Glu Glu Lys
1 5 10
<210> 3415
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3415
Leu Lys Thr Pro Ile Thr Phe Arg
1 5
<210> 3416
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3416
Leu Lys Tyr Glu Asn Glu Val Ala Leu Arg
1 5 10
<210> 3417
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3417
Leu Leu Ala Ala Ala Arg
1 5
<210> 3418
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3418
Leu Leu Ala Ala Leu Leu Glu Asp Glu Gly Gly Ser Gly Arg Pro Leu
1 5 10 15
Leu Gln Ala Ala Lys
20
<210> 3419
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3419
Leu Leu Ala Gly Asp His Pro Ile Asp Leu Leu Leu Arg
1 5 10
<210> 3420
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3420
Leu Leu Ala His Gln Lys Pro Pro Lys
1 5
<210> 3421
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3421
Leu Leu Ala Ser Tyr Pro His Thr Arg
1 5
<210> 3422
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3422
Leu Leu Ala Thr Val Leu Ser Gln Lys
1 5
<210> 3423
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3423
Leu Leu Cys Gln Cys Leu Gly Phe Gly Ser Gly His Phe Arg
1 5 10
<210> 3424
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3424
Leu Leu Asp Phe Gln Lys Thr Lys
1 5
<210> 3425
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3425
Leu Leu Asp His Arg Val Pro Gln Thr Asp Met Thr Phe Arg
1 5 10
<210> 3426
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3426
Leu Leu Asp Asn Trp Asp Ser Val Thr Ser Thr Phe Ser Lys
1 5 10
<210> 3427
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3427
Leu Leu Asp Ser Leu Pro Ser Asp Thr Arg
1 5 10
<210> 3428
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3428
Leu Leu Asp Ser Ser Thr Val Thr His Leu Phe Lys
1 5 10
<210> 3429
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3429
Leu Leu Asp Ser Val Glu Gln Asp Phe His Leu Glu Ile Ala Lys
1 5 10 15
<210> 3430
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3430
Leu Leu Glu Leu Phe Pro Val Asn Arg
1 5
<210> 3431
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3431
Leu Leu Glu Leu Thr Gly Pro Lys
1 5
<210> 3432
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3432
Leu Leu Glu Thr Ile Asp Gln Leu Tyr Leu Glu Tyr Ala Lys
1 5 10
<210> 3433
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3433
Leu Leu Glu Val Pro Glu Gly Arg
1 5
<210> 3434
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3434
Leu Leu Phe Asp Gly Asp Ala His Leu Leu Met Ser Ile Pro Ser Pro
1 5 10 15
Phe Arg
<210> 3435
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3435
Leu Leu Phe Lys Gly Ser Glu Met Val Val Ala Gly Lys
1 5 10
<210> 3436
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3436
Leu Leu Phe Lys Lys
1 5
<210> 3437
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3437
Leu Leu Gly Glu Leu Leu Gln Asp Asn Ala Lys
1 5 10
<210> 3438
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3438
Leu Leu Gly Glu Val Asp His Tyr Gln Leu Ala Leu Gly Lys
1 5 10
<210> 3439
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3439
Leu Leu Gly His Leu Val Lys
1 5
<210> 3440
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3440
Leu Leu Gly Ile Glu Thr Pro Leu Pro Lys
1 5 10
<210> 3441
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3441
Leu Leu Gly Leu Ser Leu Ala Gly Lys
1 5
<210> 3442
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3442
Leu Leu Gly Asn Val Leu Val Cys Val Leu Ala His His Phe Gly Lys
1 5 10 15
<210> 3443
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3443
Leu Leu Ile Asp Ser Val His Ala Arg
1 5
<210> 3444
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3444
Leu Leu Ile Phe Lys
1 5
<210> 3445
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3445
Leu Leu Ile Gly Thr Val Phe His Lys
1 5
<210> 3446
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3446
Leu Leu Ile Ile Lys
1 5
<210> 3447
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3447
Leu Leu Ile Ile Arg
1 5
<210> 3448
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3448
Leu Leu Ile Leu Glu Ala Gly His Arg
1 5
<210> 3449
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3449
Leu Leu Ile Leu Lys
1 5
<210> 3450
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3450
Leu Leu Ile Leu Arg
1 5
<210> 3451
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3451
Leu Leu Ile Asn Leu Leu Lys
1 5
<210> 3452
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3452
Leu Leu Ile Gln Met Lys
1 5
<210> 3453
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3453
Leu Leu Ile Ser Leu Ser Glu Glu Arg
1 5
<210> 3454
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3454
Leu Leu Ile Tyr Ala Ala Ser Ser Leu Gln Ser Gly Ile Pro Ser Arg
1 5 10 15
<210> 3455
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3455
Leu Leu Ile Tyr Ala Val Leu Pro Thr Gly Asp Val Ile Gly Asp Ser
1 5 10 15
Ala Lys
<210> 3456
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3456
Leu Leu Ile Tyr Asp Ala Ser Asn Arg
1 5
<210> 3457
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3457
Leu Leu Ile Tyr Gly Ala Ser Thr Arg
1 5
<210> 3458
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3458
Leu Leu Ile Tyr Lys
1 5
<210> 3459
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3459
Leu Leu Ile Tyr Lys Gln Gly Arg
1 5
<210> 3460
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3460
Leu Leu Ile Tyr Arg
1 5
<210> 3461
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3461
Leu Leu Lys Pro Ala Val Val Gly Ile Lys
1 5 10
<210> 3462
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3462
Leu Leu Leu Asp Ala Met Lys
1 5
<210> 3463
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3463
Leu Leu Leu Asp Met Tyr Lys
1 5
<210> 3464
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3464
Leu Leu Leu Glu His Tyr Arg
1 5
<210> 3465
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3465
Leu Leu Leu Glu Leu His His Arg
1 5
<210> 3466
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3466
Leu Leu Leu Phe Lys
1 5
<210> 3467
<211> 26
<212> PRT
<213> Homo sapiens
<400> 3467
Leu Leu Leu Phe Ser Pro Ser Val Val His Leu Gly Val Pro Leu Ser
1 5 10 15
Val Gly Val Gln Leu Gln Asp Val Pro Arg
20 25
<210> 3468
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3468
Leu Leu Leu His Phe Gln Ser Pro Arg
1 5
<210> 3469
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3469
Leu Leu Leu Ile Arg
1 5
<210> 3470
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3470
Leu Leu Leu Leu Lys
1 5
<210> 3471
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3471
Leu Leu Leu Leu Arg
1 5
<210> 3472
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3472
Leu Leu Leu Met Gly Ala Arg
1 5
<210> 3473
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3473
Leu Leu Leu Pro His Trp Ala Lys
1 5
<210> 3474
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3474
Leu Leu Leu Gln Ile Asn Pro Glu Arg
1 5
<210> 3475
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3475
Leu Leu Leu Gln Met Asp Ser Ser Ala Thr Ala Tyr Gly Ser Thr Val
1 5 10 15
Ser Lys
<210> 3476
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3476
Leu Leu Leu Gln Met Asp Ser Ser Ala Thr Ala Tyr Gly Ser Thr Val
1 5 10 15
Ser Lys Arg
<210> 3477
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3477
Leu Leu Leu Gln Pro Ser Pro Gln Arg
1 5
<210> 3478
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3478
Leu Leu Leu Gln Gln Val Ser Leu Pro Glu Leu Pro Gly Glu Tyr Ser
1 5 10 15
Met Lys
<210> 3479
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3479
Leu Leu Leu Ser Glu Gln Leu Ser Arg
1 5
<210> 3480
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3480
Leu Leu Leu Ser Pro Ser Val Gln Arg
1 5
<210> 3481
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3481
Leu Leu Leu Ser Arg Gly Ala Asn Ile Asn Ala Phe Asp Lys
1 5 10
<210> 3482
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3482
Leu Leu Leu Ser Tyr Gly Ala Ser Arg
1 5
<210> 3483
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3483
Leu Leu Leu Val Leu Asn Lys
1 5
<210> 3484
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3484
Leu Leu Leu Val Met Asp Lys
1 5
<210> 3485
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3485
Leu Leu Leu Tyr Gly Leu His His Gly Lys
1 5 10
<210> 3486
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3486
Leu Leu Leu Tyr Arg
1 5
<210> 3487
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3487
Leu Leu Asn Leu Asp Gly Thr Cys Ala Asp Ser Tyr Ser Phe Val Phe
1 5 10 15
Ser Arg
<210> 3488
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3488
Leu Leu Pro Ala Gln Leu Pro Ala Glu Lys
1 5 10
<210> 3489
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3489
Leu Leu Pro His Ala Asn Glu Val Ser Gln Lys
1 5 10
<210> 3490
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3490
Leu Leu Pro Val Gly Arg
1 5
<210> 3491
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3491
Leu Leu Gln Asp Glu Phe Pro Gly Ile Pro Ser Pro Leu Asp Ala Ala
1 5 10 15
Val Glu Cys His Arg
20
<210> 3492
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3492
Leu Leu Gln Lys Gly Trp Val Asp Leu Phe Val Pro Lys
1 5 10
<210> 3493
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3493
Leu Leu Gln Leu Leu Gly Arg
1 5
<210> 3494
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3494
Leu Leu Gln Leu Leu Gln Ala Lys
1 5
<210> 3495
<211> 26
<212> PRT
<213> Homo sapiens
<400> 3495
Leu Leu Gln Leu Pro Leu Gly Phe Leu Tyr Val His His Thr Tyr Val
1 5 10 15
Pro Ala Pro Pro Cys Thr Asp Phe Thr Arg
20 25
<210> 3496
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3496
Leu Leu Arg Pro Gln Ile Leu Arg
1 5
<210> 3497
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3497
Leu Leu Ser Gly Gly Asn Thr Leu His Leu Val Ser Thr Thr Lys
1 5 10 15
<210> 3498
<211> 26
<212> PRT
<213> Homo sapiens
<400> 3498
Leu Leu Ser Gly Val Leu Phe His Ser Ser Pro Ala Leu Gln Pro Ala
1 5 10 15
Ala Asp His Lys Pro Gly Pro Gly Ala Arg
20 25
<210> 3499
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3499
Leu Leu Ser Ile Arg
1 5
<210> 3500
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3500
Leu Leu Ser Leu Gly Ala Gly Glu Phe Lys
1 5 10
<210> 3501
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3501
Leu Leu Ser Leu Arg
1 5
<210> 3502
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3502
Leu Leu Ser Val Lys
1 5
<210> 3503
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3503
Leu Leu Thr Thr Glu Glu Lys Pro Arg
1 5
<210> 3504
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3504
Leu Leu Val Gly Asn Lys
1 5
<210> 3505
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3505
Leu Leu Val Val Tyr Pro Trp Thr Gln Arg
1 5 10
<210> 3506
<211> 27
<212> PRT
<213> Homo sapiens
<400> 3506
Leu Leu Val Tyr Tyr Ile Val Thr Gly Glu Gln Thr Ala Glu Leu Val
1 5 10 15
Ser Asp Ser Val Trp Leu Asn Ile Glu Glu Lys
20 25
<210> 3507
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3507
Leu Leu Trp Ser Arg
1 5
<210> 3508
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3508
Leu Met Glu Leu Ile Arg
1 5
<210> 3509
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3509
Leu Met Gly Ala Phe Ala Ser Leu Asp Leu Lys
1 5 10
<210> 3510
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3510
Leu Met Gly Ile Arg
1 5
<210> 3511
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3511
Leu Met Leu Ser Tyr Asp Leu Lys
1 5
<210> 3512
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3512
Leu Met Asn His Tyr Ile Asn Lys
1 5
<210> 3513
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3513
Leu Met Asn Ile Phe Leu Lys
1 5
<210> 3514
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3514
Leu Met Gln Cys Leu Pro Asn Pro Glu Asp Val Lys
1 5 10
<210> 3515
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3515
Leu Met Val Glu Leu His Asn Leu Tyr Arg
1 5 10
<210> 3516
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3516
Leu Asn Ala Ala Lys
1 5
<210> 3517
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3517
Leu Asn Asp Leu Glu Asp Ala Leu Gln Gln Ala Lys
1 5 10
<210> 3518
<211> 26
<212> PRT
<213> Homo sapiens
<400> 3518
Leu Asn Asp Leu Asn Ser Val Leu Val Met Pro Thr Phe His Val Pro
1 5 10 15
Phe Thr Asp Leu Gln Val Pro Ser Cys Lys
20 25
<210> 3519
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3519
Leu Asn Glu His Phe Leu Asn Thr Thr Asp Phe Leu Asp Thr Ile Lys
1 5 10 15
<210> 3520
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3520
Leu Asn Glu Arg Glu Val Val Lys
1 5
<210> 3521
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3521
Leu Asn Phe Ser His Gly Thr His Glu Tyr His Ala Glu Thr Ile Lys
1 5 10 15
<210> 3522
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3522
Leu Asn Gly Glu Ile Gln Ala Leu Glu Leu Pro Gln Lys
1 5 10
<210> 3523
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3523
Leu Asn Gly Glu Ile Gln Ala Leu Glu Leu Pro Gln Lys Ala Glu Ala
1 5 10 15
Leu Lys
<210> 3524
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3524
Leu Asn Gly Glu Ser Asn Leu Arg
1 5
<210> 3525
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3525
Leu Asn His Gln Leu Glu Gly Leu Thr Phe Gln Met Lys
1 5 10
<210> 3526
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3526
Leu Asn Ile Leu Asn Ala Lys
1 5
<210> 3527
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3527
Leu Asn Ile Leu Asn Ala Lys Phe Ala Phe Asn Leu Tyr Arg
1 5 10
<210> 3528
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3528
Leu Asn Ile Asn Leu Lys
1 5
<210> 3529
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3529
Leu Asn Leu Ala Phe Ile Ala Asn Leu Phe Asn Arg
1 5 10
<210> 3530
<211> 27
<212> PRT
<213> Homo sapiens
<400> 3530
Leu Asn Leu Glu Val Thr Ala Leu Ile Glu Lys Pro Asp Ile His Phe
1 5 10 15
Leu Glu Pro Leu Glu Ser Gly Arg Pro Thr Arg
20 25
<210> 3531
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3531
Leu Asn Leu Thr Leu Ser Pro Ala Lys Lys
1 5 10
<210> 3532
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3532
Leu Asn Leu Val Ala Thr Pro Leu Phe Leu Lys Pro Gly Ile Pro Tyr
1 5 10 15
Pro Ile Lys
<210> 3533
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3533
Leu Asn Leu Val Gln Arg
1 5
<210> 3534
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3534
Leu Asn Met Gly Ile Thr Asp Leu Gln Gly Leu Arg
1 5 10
<210> 3535
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3535
Leu Asn Asn Gly Glu Ile Thr Gln His Arg
1 5 10
<210> 3536
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3536
Leu Asn Asn Gly Glu Ile Thr Gln His Arg Lys
1 5 10
<210> 3537
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3537
Leu Asn Gln Ala Leu Leu Asp Leu His Ala Leu Gly Ser Ala Arg
1 5 10 15
<210> 3538
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3538
Leu Asn Gln Glu Val Ala Leu Asn Leu Lys
1 5 10
<210> 3539
<211> 30
<212> PRT
<213> Homo sapiens
<400> 3539
Leu Asn Thr Asp Ile Ala Gly Leu Ala Ser Ala Ile Asp Met Ser Thr
1 5 10 15
Asn Tyr Asn Ser Asp Ser Leu His Phe Ser Asn Val Phe Arg
20 25 30
<210> 3540
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3540
Leu Asn Thr Ser Arg
1 5
<210> 3541
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3541
Leu Asn Tyr Lys Pro Pro Pro Gln Lys
1 5
<210> 3542
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3542
Leu Pro Ala Leu His Ile Ala Ala Arg
1 5
<210> 3543
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3543
Leu Pro Ala Asn His Pro Leu Leu Thr Gly Gln Arg
1 5 10
<210> 3544
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3544
Leu Pro Ala Asn Leu Leu Tyr Lys
1 5
<210> 3545
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3545
Leu Pro Ala Ser His Ala Thr Trp Met Gly Lys
1 5 10
<210> 3546
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3546
Leu Pro Ala Thr Glu Lys Pro Val Leu Leu Ser Lys
1 5 10
<210> 3547
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3547
Leu Pro Asp Ala Thr Pro Thr Glu Leu Ala Lys
1 5 10
<210> 3548
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3548
Leu Pro Glu Cys Arg
1 5
<210> 3549
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3549
Leu Pro Glu Glu Ile Gln Arg
1 5
<210> 3550
<211> 25
<212> PRT
<213> Homo sapiens
<400> 3550
Leu Pro Glu Gly Ser Val Ser Leu Ile Ile Leu Leu Thr Asp Gly Asp
1 5 10 15
Pro Thr Val Gly Glu Thr Asn Pro Arg
20 25
<210> 3551
<211> 45
<212> PRT
<213> Homo sapiens
<400> 3551
Leu Pro Glu Ile Ala Ile Pro Glu Phe Ile Ile Pro Thr Leu Asn Leu
1 5 10 15
Asn Asp Phe Gln Val Pro Asp Leu His Ile Pro Glu Phe Gln Leu Pro
20 25 30
His Ile Ser His Thr Ile Glu Val Pro Thr Phe Gly Lys
35 40 45
<210> 3552
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3552
Leu Pro Glu Thr Ile Asp Leu Gly Ala Leu Tyr Leu Ser Met Lys
1 5 10 15
<210> 3553
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3553
Leu Pro Phe Pro Ile Ile Asp Asp Arg
1 5
<210> 3554
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3554
Leu Pro Gly Ile Val Ala Glu Gly Arg
1 5
<210> 3555
<211> 20
<212> PRT
<213> Homo sapiens
<400> 3555
Leu Pro Gly Ile Val Ala Glu Gly Arg Asp Asp Leu Tyr Val Ser Asp
1 5 10 15
Ala Phe His Lys
20
<210> 3556
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3556
Leu Pro Gly Leu His Asn Ser Leu Val Lys
1 5 10
<210> 3557
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3557
Leu Pro Gly Ser Ser Lys
1 5
<210> 3558
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3558
Leu Pro Ile Pro Arg
1 5
<210> 3559
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3559
Leu Pro Ile Ser Arg
1 5
<210> 3560
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3560
Leu Pro Lys Pro Val Gln Asp Leu Ile Lys
1 5 10
<210> 3561
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3561
Leu Pro Leu Glu Tyr Ser Tyr Gly Glu Tyr Arg
1 5 10
<210> 3562
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3562
Leu Pro Leu Ile Phe His Leu Gly Arg
1 5
<210> 3563
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3563
Leu Pro Leu Pro Arg
1 5
<210> 3564
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3564
Leu Pro Leu Ser Arg
1 5
<210> 3565
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3565
Leu Pro Met Ser Val Arg
1 5
<210> 3566
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3566
Leu Pro Asn Leu Ser Ser Leu Thr Leu Ser Arg
1 5 10
<210> 3567
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3567
Leu Pro Asn Asn Val Leu Gln Glu Lys
1 5
<210> 3568
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3568
Leu Pro Pro Ile Arg
1 5
<210> 3569
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3569
Leu Pro Pro Leu Arg
1 5
<210> 3570
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3570
Leu Pro Pro Leu Arg Lys
1 5
<210> 3571
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3571
Leu Pro Pro Asn Val Val Glu Glu Ser Ala Arg
1 5 10
<210> 3572
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3572
Leu Pro Pro Thr Asp Ala Tyr Tyr Lys
1 5
<210> 3573
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3573
Leu Pro Pro Thr Thr Thr Cys Gln Gln Gln Lys Glu Glu Leu Leu Pro
1 5 10 15
Ala Gln Asp Ile Lys
20
<210> 3574
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3574
Leu Pro Gln Gln Ala Asn Asp Tyr Leu Asn Ser Phe Asn Trp Glu Arg
1 5 10 15
<210> 3575
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3575
Leu Pro Arg Leu Pro Lys
1 5
<210> 3576
<211> 24
<212> PRT
<213> Homo sapiens
<400> 3576
Leu Pro Ser Glu Gly Pro Arg Pro Ala His Val Val Val Gly Asp Val
1 5 10 15
Leu Gln Ala Ala Asp Val Asp Lys
20
<210> 3577
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3577
Leu Pro Ser Phe Leu Ala Asn Val His Lys
1 5 10
<210> 3578
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3578
Leu Pro Ser Gly Leu Pro Val Ser Leu Leu Thr Leu Tyr Leu Asp Asn
1 5 10 15
Asn Lys
<210> 3579
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3579
Leu Pro Ser Gly Ser Asp His Val Met Leu Lys
1 5 10
<210> 3580
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3580
Leu Pro Thr Asp Ser Glu Leu Ala Pro Arg
1 5 10
<210> 3581
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3581
Leu Pro Thr Gly Ile Asn Pro Leu Thr Leu His Ile Met Arg
1 5 10
<210> 3582
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3582
Leu Pro Val Ala Pro Leu Arg
1 5
<210> 3583
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3583
Leu Pro Val Ala Pro Leu Arg Lys
1 5
<210> 3584
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3584
Leu Pro Val Lys Lys
1 5
<210> 3585
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3585
Leu Pro Val Pro Ala Val Lys
1 5
<210> 3586
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3586
Leu Pro Val Ser Leu Ser Glu Gly Arg
1 5
<210> 3587
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3587
Leu Pro Val Val Leu Ala Asn Gly Gln Ile Arg
1 5 10
<210> 3588
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3588
Leu Pro Tyr Gln Cys Pro Lys
1 5
<210> 3589
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3589
Leu Pro Tyr Ser Val Val Arg
1 5
<210> 3590
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3590
Leu Pro Tyr Thr Ile Ile Thr Thr Pro Pro Leu Lys
1 5 10
<210> 3591
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3591
Leu Pro Tyr Thr Ile Ile Thr Thr Pro Pro Leu Lys Asp Phe Ser Leu
1 5 10 15
Trp Glu Lys
<210> 3592
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3592
Leu Gln Ala Glu Ala Phe Gln Ala Arg
1 5
<210> 3593
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3593
Leu Gln Ala Ile Leu Gly Val Pro Trp Lys
1 5 10
<210> 3594
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3594
Leu Gln Ala Ile Leu Gly Val Pro Trp Lys Asp Lys
1 5 10
<210> 3595
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3595
Leu Gln Ala Val Thr Asp Asp His Ile Arg
1 5 10
<210> 3596
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3596
Leu Gln Asp Ala Glu Ile Ala Arg
1 5
<210> 3597
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3597
Leu Gln Asp Glu Val Lys
1 5
<210> 3598
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3598
Leu Gln Asp Phe Ser Asp Gln Leu Ser Asp Tyr Tyr Glu Lys
1 5 10
<210> 3599
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3599
Leu Gln Asp Asn Glu Leu Arg
1 5
<210> 3600
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3600
Leu Gln Asp Arg Gly Pro Asp Val Leu Thr Ala Thr Val Ser Gly Lys
1 5 10 15
<210> 3601
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3601
Leu Gln Asp Val Lys
1 5
<210> 3602
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3602
Leu Gln Glu Glu Met Ala Leu Gln Gln Glu Lys
1 5 10
<210> 3603
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3603
Leu Gln Glu Gly Tyr Asp His Ser Tyr Tyr Phe Ile Ala Thr Phe Ile
1 5 10 15
Thr Asp His Ile Arg
20
<210> 3604
<211> 26
<212> PRT
<213> Homo sapiens
<400> 3604
Leu Gln Glu Leu His Leu Ser Ser Asn Gly Leu Glu Ser Leu Ser Pro
1 5 10 15
Glu Phe Leu Arg Pro Val Pro Gln Leu Arg
20 25
<210> 3605
<211> 27
<212> PRT
<213> Homo sapiens
<400> 3605
Leu Gln Glu Thr Ser Asn Trp Leu Leu Ser Gln Gln Gln Ala Asp Gly
1 5 10 15
Ser Phe Gln Asp Leu Ser Pro Val Ile His Arg
20 25
<210> 3606
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3606
Leu Gln Gly Glu Ile Ala His Val Lys
1 5
<210> 3607
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3607
Leu Gln Gly Leu Ile Pro Gly Ala Arg
1 5
<210> 3608
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3608
Leu Gln Gly Gln Gly Lys
1 5
<210> 3609
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3609
Leu Gln Gly Thr Leu Pro Val Glu Ala Arg
1 5 10
<210> 3610
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3610
Leu Gln Gly Val Glu Arg Ile Met Lys
1 5
<210> 3611
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3611
Leu Gln His Leu Glu Asn Glu Leu Thr His Asp Ile Ile Thr Lys
1 5 10 15
<210> 3612
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3612
Leu Gln His Val Asp Arg Pro Leu Ser Val Arg
1 5 10
<210> 3613
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3613
Leu Gln Ile Ala Gln Leu Arg Pro Ser Ser Asn Tyr Leu Ala Leu Arg
1 5 10 15
<210> 3614
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3614
Leu Gln Ile Leu Ser Leu Arg
1 5
<210> 3615
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3615
Leu Gln Ile Gln Glu Lys
1 5
<210> 3616
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3616
Leu Gln Leu Asp Arg Ala Arg
1 5
<210> 3617
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3617
Leu Gln Leu Lys His Leu Ser Leu Leu Thr Thr Leu Ser Asn Arg
1 5 10 15
<210> 3618
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3618
Leu Gln Leu Leu Leu Leu Asn Pro Leu Lys
1 5 10
<210> 3619
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3619
Leu Gln Leu Gln Glu Lys
1 5
<210> 3620
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3620
Leu Gln Asn Asn Glu Asn Asn Ile Ser Cys Val Glu Arg
1 5 10
<210> 3621
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3621
Leu Gln Pro Leu Asp Phe Lys
1 5
<210> 3622
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3622
Leu Gln Pro Leu Asp Phe Lys Glu Asn Ala Glu Gln Ser Arg
1 5 10
<210> 3623
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3623
Leu Gln Pro Leu Lys
1 5
<210> 3624
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3624
Leu Gln Gln Glu Leu Asp Asp Leu Leu Val Asp Leu Asp His Gln Arg
1 5 10 15
<210> 3625
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3625
Leu Gln Gln Glu Asn Met Glu Met Gly Glu Lys
1 5 10
<210> 3626
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3626
Leu Gln Gln Leu Lys Arg
1 5
<210> 3627
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3627
Leu Gln Gln Val Leu His Ala Gly Ser Gly Pro Cys Leu Pro His Leu
1 5 10 15
Leu Ser Arg
<210> 3628
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3628
Leu Gln Ser Ile Gly Thr Glu Asn Thr Glu Glu Asn Arg
1 5 10
<210> 3629
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3629
Leu Gln Ser Ile Gly Thr Glu Asn Thr Glu Glu Asn Arg Arg
1 5 10
<210> 3630
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3630
Leu Gln Ser Leu Phe Asp Ser Pro Asp Phe Ser Lys
1 5 10
<210> 3631
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3631
Leu Gln Ser Leu His Leu Tyr Arg
1 5
<210> 3632
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3632
Leu Gln Val Glu Leu Asp Asn Val Thr Gly Leu Leu Ser Gln Ser Asp
1 5 10 15
Ser Lys
<210> 3633
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3633
Leu Gln Val Phe Gln Ala Leu Arg
1 5
<210> 3634
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3634
Leu Gln Val Ile Phe Lys
1 5
<210> 3635
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3635
Leu Gln Val Leu Gly Lys
1 5
<210> 3636
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3636
Leu Gln Val Leu Gly Lys Asp Leu Leu Leu Pro Gln Pro Asp Leu Arg
1 5 10 15
<210> 3637
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3637
Leu Gln Val Leu Arg Val Lys
1 5
<210> 3638
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3638
Leu Gln Tyr Val Lys
1 5
<210> 3639
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3639
Leu Arg Glu Glu Ile Glu Gly Lys
1 5
<210> 3640
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3640
Leu Arg Glu Gln Leu Gly Pro Val Thr Gln Glu Phe Trp Asp Asn Leu
1 5 10 15
Glu Lys
<210> 3641
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3641
Leu Arg Leu Glu Pro Gly Lys
1 5
<210> 3642
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3642
Leu Arg Leu Glu Pro Leu Lys
1 5
<210> 3643
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3643
Leu Arg Asn Gly His Val Gly Ile Ser Phe Val Pro Lys
1 5 10
<210> 3644
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3644
Leu Arg Asn Gln Thr Asp Leu Lys
1 5
<210> 3645
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3645
Leu Arg Pro Leu Trp Lys
1 5
<210> 3646
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3646
Leu Arg Thr Glu Gly Asp Gly Val Tyr Thr Leu Asn Asp Lys
1 5 10
<210> 3647
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3647
Leu Arg Thr Glu Gly Asp Gly Val Tyr Thr Leu Asn Asn Glu Lys
1 5 10 15
<210> 3648
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3648
Leu Arg Val Asp Pro Val Asn Phe Lys
1 5
<210> 3649
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3649
Leu Ser Ala Gly Ser Ala Ala Leu Arg
1 5
<210> 3650
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3650
Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Asp Asp Tyr Ala Met His
1 5 10 15
Trp Val Arg
<210> 3651
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3651
Leu Ser Asp Leu Leu Ala Pro Ile Ser Glu Gln Ile Lys
1 5 10
<210> 3652
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3652
Leu Ser Asp Leu Leu Lys
1 5
<210> 3653
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3653
Leu Ser Glu Ala Glu Phe Glu Val Leu Lys
1 5 10
<210> 3654
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3654
Leu Ser Glu Asp Tyr Gly Val Leu Lys
1 5
<210> 3655
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3655
Leu Ser Glu Glu Pro Leu Gln Val Leu Glu His Pro Arg
1 5 10
<210> 3656
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3656
Leu Ser Glu Gly Ala Ser Tyr Leu Asp His Thr Phe Pro Ala Glu Lys
1 5 10 15
<210> 3657
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3657
Leu Ser Glu Gly Phe Ser Ile His Thr Arg
1 5 10
<210> 3658
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3658
Leu Ser Glu Lys His Glu Gly Ser Phe Ile Gln Gly Ala Glu Lys
1 5 10 15
<210> 3659
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3659
Leu Ser Glu Tyr Ser His His Phe Val Ser Ala Phe Ala Arg
1 5 10
<210> 3660
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3660
Leu Ser Phe Phe Arg
1 5
<210> 3661
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3661
Leu Ser Phe Gln Glu Phe Leu Lys
1 5
<210> 3662
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3662
Leu Ser Phe Val Lys
1 5
<210> 3663
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3663
Leu Ser Phe Val Lys Val Asp Ser His Phe Arg
1 5 10
<210> 3664
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3664
Leu Ser Phe Tyr Tyr Leu Ile Met Ala Lys
1 5 10
<210> 3665
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3665
Leu Ser Phe Tyr Tyr Leu Ile Met Ala Lys Gly Gly Ile Val Arg
1 5 10 15
<210> 3666
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3666
Leu Ser Gly Ala Leu His Val Tyr Ser Leu Gly Ser Asp
1 5 10
<210> 3667
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3667
Leu Ser Gly Leu Pro Lys
1 5
<210> 3668
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3668
Leu Ser Gly Asn Val Leu Ser Tyr Thr Phe Gln Val Lys
1 5 10
<210> 3669
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3669
Leu Ser Gly Ser His Ser Gln Gly Val Ala Tyr Pro Val Arg
1 5 10
<210> 3670
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3670
Leu Ser His Asn Ala Ile Ala Ser Leu Arg Pro Arg
1 5 10
<210> 3671
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3671
Leu Ser Ile Cys Phe Met Lys
1 5
<210> 3672
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3672
Leu Ser Ile Met Lys
1 5
<210> 3673
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3673
Leu Ser Ile Asn Thr His Pro Ser Gln Lys Pro Leu Ser Ile Thr Val
1 5 10 15
Arg
<210> 3674
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3674
Leu Ser Ile Thr Gly Thr Tyr Asp Leu Lys
1 5 10
<210> 3675
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3675
Leu Ser Leu Ala Ser Lys
1 5
<210> 3676
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3676
Leu Ser Leu Glu Ile Glu Gln Leu Glu Leu Gln Arg
1 5 10
<210> 3677
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3677
Leu Ser Leu Glu Ser Leu Thr Ser Tyr Phe Ser Ile Glu Ser Ser Thr
1 5 10 15
Lys
<210> 3678
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3678
Leu Ser Leu Glu Ser Leu Thr Ser Tyr Phe Ser Ile Glu Ser Ser Thr
1 5 10 15
Lys Gly Asp Val Lys
20
<210> 3679
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3679
Leu Ser Leu Gly Pro Arg
1 5
<210> 3680
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3680
Leu Ser Leu His Gly Asp Ile Arg
1 5
<210> 3681
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3681
Leu Ser Leu Leu Glu Glu Leu Ser Leu Ala Glu Asn Gln Leu Leu Lys
1 5 10 15
<210> 3682
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3682
Leu Ser Leu Met Lys
1 5
<210> 3683
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3683
Leu Ser Leu Pro Asp Phe Lys
1 5
<210> 3684
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3684
Leu Ser Met Asp Gly Ser Pro Thr Arg
1 5
<210> 3685
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3685
Leu Ser Met Asp Ile Asp Val Ser Tyr Lys
1 5 10
<210> 3686
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3686
Leu Ser Met Asp Ile Asp Val Ser Tyr Lys His Lys
1 5 10
<210> 3687
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3687
Leu Ser Met Glu Ile Lys
1 5
<210> 3688
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3688
Leu Ser Asn Ala Ala His Lys
1 5
<210> 3689
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3689
Leu Ser Asn Asp Met Met Gly Ser Tyr Ala Glu Met Lys
1 5 10
<210> 3690
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3690
Leu Ser Asn Glu Asn His Gly Ile Ala Gln Arg
1 5 10
<210> 3691
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3691
Leu Ser Asn His Ile Ser Ser Leu Phe Arg
1 5 10
<210> 3692
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3692
Leu Ser Asn Leu Ile Lys
1 5
<210> 3693
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3693
Leu Ser Asn Asn Ala Leu Ser Gly Leu Pro Gln Gly Val Phe Gly Lys
1 5 10 15
<210> 3694
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3694
Leu Ser Asn Arg Pro Ala Phe Met Pro Ser Glu Gly Arg
1 5 10
<210> 3695
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3695
Leu Ser Pro Glu Asp Tyr Thr Leu Lys
1 5
<210> 3696
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3696
Leu Ser Pro Glu Glu Leu Leu Leu Arg
1 5
<210> 3697
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3697
Leu Ser Pro Glu Gly Lys
1 5
<210> 3698
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3698
Leu Ser Pro His Ala Phe Lys
1 5
<210> 3699
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3699
Leu Ser Pro Ile Tyr Asn Leu Val Pro Val Lys
1 5 10
<210> 3700
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3700
Leu Ser Pro Leu Gly Glu Glu Met Arg
1 5
<210> 3701
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3701
Leu Ser Pro Leu Gly Glu Glu Met Arg Asp Arg
1 5 10
<210> 3702
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3702
Leu Ser Pro Val Tyr Ala Gly Lys
1 5
<210> 3703
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3703
Leu Ser Gln Glu Asp Pro Asp Tyr Gly Ile Arg
1 5 10
<210> 3704
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3704
Leu Ser Ser Gly Leu Val Thr Ala Ala Leu Tyr Gly Arg
1 5 10
<210> 3705
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3705
Leu Ser Ser Asn Gly Ser Pro Thr Lys
1 5
<210> 3706
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3706
Leu Ser Ser Pro Ala Val Ile Thr Asp Lys
1 5 10
<210> 3707
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3707
Leu Ser Ser Trp Val Leu Leu Met Lys
1 5
<210> 3708
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3708
Leu Ser Val Asp Gly Arg
1 5
<210> 3709
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3709
Leu Ser Val Asp Lys
1 5
<210> 3710
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3710
Leu Ser Val Gly Thr Leu Lys Lys
1 5
<210> 3711
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3711
Leu Ser Val Ile Arg
1 5
<210> 3712
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3712
Leu Ser Val Leu Arg
1 5
<210> 3713
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3713
Leu Ser Tyr Glu Gly Glu Val Thr Lys
1 5
<210> 3714
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3714
Leu Ser Tyr Thr Cys Glu Gly Gly Phe Arg
1 5 10
<210> 3715
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3715
Leu Thr Ala Leu Thr Lys
1 5
<210> 3716
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3716
Leu Thr Ala Leu Thr Lys Lys
1 5
<210> 3717
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3717
Leu Thr Asp Val Lys
1 5
<210> 3718
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3718
Leu Thr Glu Val Leu Leu Gly His Asn Ser Trp Arg
1 5 10
<210> 3719
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3719
Leu Thr Gly Ile Ser Asp Pro Val Thr Val Lys
1 5 10
<210> 3720
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3720
Leu Thr Gly Ser Ser Gly Phe Val Thr Asp Gly Pro Gly Asn Tyr Lys
1 5 10 15
<210> 3721
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3721
Leu Thr Ile Phe Lys
1 5
<210> 3722
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3722
Leu Thr Ile Phe Lys Thr Glu Leu Arg
1 5
<210> 3723
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3723
Leu Thr Ile Gly Glu Gly Gln Gln His His Leu Gly Gly Ala Lys
1 5 10 15
<210> 3724
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3724
Leu Thr Ile Pro Arg
1 5
<210> 3725
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3725
Leu Thr Ile Ser Glu Gln Asn Ile Gln Arg
1 5 10
<210> 3726
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3726
Leu Thr Ile Ser Lys
1 5
<210> 3727
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3727
Leu Thr Leu Asp Ile Gln Asn Lys
1 5
<210> 3728
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3728
Leu Thr Leu Asp Ile Gln Asn Lys Lys
1 5
<210> 3729
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3729
Leu Thr Leu Asp Lys Leu Asp Val Lys
1 5
<210> 3730
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3730
Leu Thr Leu Lys Ser Leu Glu Val Glu Leu Lys
1 5 10
<210> 3731
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3731
Leu Thr Leu Leu Ala Pro Leu Asn Ser Val Phe Lys
1 5 10
<210> 3732
<211> 37
<212> PRT
<213> Homo sapiens
<400> 3732
Leu Thr Leu Asn Phe Asn Met Leu Glu Ala Leu Pro Glu Gly Leu Phe
1 5 10 15
Gln His Leu Ala Ala Leu Glu Ser Leu His Leu Gln Gly Asn Gln Leu
20 25 30
Gln Ala Leu Pro Arg
35
<210> 3733
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3733
Leu Thr Leu Pro Arg
1 5
<210> 3734
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3734
Leu Thr Leu Ser Lys
1 5
<210> 3735
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3735
Leu Thr Leu Ser Arg
1 5
<210> 3736
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3736
Leu Thr Leu Thr Lys
1 5
<210> 3737
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3737
Leu Thr Leu Thr Pro Trp Val Gly Leu Arg
1 5 10
<210> 3738
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3738
Leu Thr Leu Thr Pro Trp Val Gly Leu Arg Lys
1 5 10
<210> 3739
<211> 22
<212> PRT
<213> Homo sapiens
<400> 3739
Leu Thr Leu Tyr Asp Ile Ala His Thr Pro Gly Val Ala Ala Asp Leu
1 5 10 15
Ser His Ile Glu Thr Lys
20
<210> 3740
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3740
Leu Thr Asn Arg Ser Pro Arg
1 5
<210> 3741
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3741
Leu Thr Pro Ala Gly Leu Ala Ile Lys
1 5
<210> 3742
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3742
Leu Thr Pro Glu Glu Ile Glu Arg
1 5
<210> 3743
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3743
Leu Thr Pro Glu Glu Leu Glu Arg
1 5
<210> 3744
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3744
Leu Thr Pro Leu Arg
1 5
<210> 3745
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3745
Leu Thr Pro Leu Tyr Glu Leu Val Lys
1 5
<210> 3746
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3746
Leu Thr Pro Tyr Ala Asp Glu Phe Lys
1 5
<210> 3747
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3747
Leu Thr Pro Tyr Ala Asp Glu Phe Lys Val Lys
1 5 10
<210> 3748
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3748
Leu Thr Gln Leu Gly Thr Phe Glu Asp His Phe Leu Ser Leu Gln Arg
1 5 10 15
<210> 3749
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3749
Leu Thr Gln Leu Asn Leu Asp Arg
1 5
<210> 3750
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3750
Leu Thr Ser Leu Pro Leu Gly Ala Leu Arg
1 5 10
<210> 3751
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3751
Leu Thr Ser Leu Ser Asp Arg
1 5
<210> 3752
<211> 30
<212> PRT
<213> Homo sapiens
<400> 3752
Leu Thr Ser Leu Ser Asp Arg Tyr Val Ser His Phe Glu Thr Glu Gly
1 5 10 15
Pro His Val Leu Leu Tyr Phe Asp Ser Val Pro Thr Ser Arg
20 25 30
<210> 3753
<211> 25
<212> PRT
<213> Homo sapiens
<400> 3753
Leu Thr Val Ala Ala Pro Pro Ser Gly Gly Pro Gly Phe Leu Ser Ile
1 5 10 15
Glu Arg Pro Asp Ser Arg Pro Pro Arg
20 25
<210> 3754
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3754
Leu Thr Val Asp Lys
1 5
<210> 3755
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3755
Leu Thr Val Gly Leu Thr Arg
1 5
<210> 3756
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3756
Leu Thr Val Leu Pro Pro Glu Leu Gly Asn Leu Asp Leu Thr Gly Gln
1 5 10 15
Lys
<210> 3757
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3757
Leu Thr Val Leu Arg
1 5
<210> 3758
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3758
Leu Thr Val Ser Ile Glu Ala Arg
1 5
<210> 3759
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3759
Leu Thr Trp Ala Ser His Glu Lys
1 5
<210> 3760
<211> 27
<212> PRT
<213> Homo sapiens
<400> 3760
Leu Thr Tyr Ala Tyr Phe Ala Gly Gly Asp Ala Gly Asp Ala Phe Asp
1 5 10 15
Gly Phe Asp Phe Gly Asp Asp Pro Ser Asp Lys
20 25
<210> 3761
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3761
Leu Thr Tyr Asn His Gly Gly Ile Thr Gly Ser Arg
1 5 10
<210> 3762
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3762
Leu Val Ala Ala Lys Cys Thr Leu Ala Ala Arg
1 5 10
<210> 3763
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3763
Leu Val Ala Leu Lys Lys
1 5
<210> 3764
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3764
Leu Val Ala Tyr Tyr Thr Leu Ile Gly Ala Ser Gly Gln Arg
1 5 10
<210> 3765
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3765
Leu Val Asp Glu Asp Met Asn Ser Phe Lys
1 5 10
<210> 3766
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3766
Leu Val Asp Glu Asp Met Asn Ser Phe Lys Ala Asp Val Lys
1 5 10
<210> 3767
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3767
Leu Val Asp Gly Lys
1 5
<210> 3768
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3768
Leu Val Asp Ile Lys
1 5
<210> 3769
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3769
Leu Val Asp Lys Phe Leu Glu Asp Val Lys
1 5 10
<210> 3770
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3770
Leu Val Asp Leu Lys
1 5
<210> 3771
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3771
Leu Val Asp Gln Asp Lys
1 5
<210> 3772
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3772
Leu Val Glu Leu Ala His Gln Tyr Lys
1 5
<210> 3773
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3773
Leu Val Glu Met Tyr Lys
1 5
<210> 3774
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3774
Leu Val Phe Asn Arg Pro Phe Leu Met Phe Ile Val Asp Asn Asn Ile
1 5 10 15
Leu Phe Leu Gly Lys
20
<210> 3775
<211> 20
<212> PRT
<213> Homo sapiens
<400> 3775
Leu Val Phe Gln Gln Phe Asp Leu Glu Pro Ser Glu Gly Cys Phe Tyr
1 5 10 15
Asp Tyr Val Lys
20
<210> 3776
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3776
Leu Val Gly Asp Val Ile Gln Arg
1 5
<210> 3777
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3777
Leu Val Gly Gly Lys
1 5
<210> 3778
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3778
Leu Val Gly Gly Leu His Arg
1 5
<210> 3779
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3779
Leu Val Gly Gly Pro Met Asp Ala Ser Val Glu Glu Glu Gly Val Arg
1 5 10 15
Arg
<210> 3780
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3780
Leu Val His Ala Asn Phe Gly Thr Lys
1 5
<210> 3781
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3781
Leu Val His Cys Pro Ile Glu Thr Gln Val Leu Arg
1 5 10
<210> 3782
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3782
Leu Val His Ile Leu Val Arg
1 5
<210> 3783
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3783
Leu Val His Val Glu Glu Pro His Thr Glu Thr Val Arg
1 5 10
<210> 3784
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3784
Leu Val His Val Glu Glu Pro His Thr Glu Thr Val Arg Lys
1 5 10
<210> 3785
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3785
Leu Val Ile Ala Gly His Leu Leu Arg
1 5
<210> 3786
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3786
Leu Val Ile Ile Glu Ser Asp Leu Glu Arg Ala Glu Glu Arg
1 5 10
<210> 3787
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3787
Leu Val Ile Ile Thr Ala Gly Ala Arg
1 5
<210> 3788
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3788
Leu Val Ile Leu Glu Gly Glu Leu Glu Arg
1 5 10
<210> 3789
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3789
Leu Val Ile Leu Glu Gly Glu Leu Glu Arg Ala Glu Glu Arg
1 5 10
<210> 3790
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3790
Leu Val Lys Pro Gln Lys
1 5
<210> 3791
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3791
Leu Val Leu Ile Arg
1 5
<210> 3792
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3792
Leu Val Leu Leu Asn Ala Ile Tyr Leu Ser Ala Lys
1 5 10
<210> 3793
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3793
Leu Val Leu Leu Arg
1 5
<210> 3794
<211> 22
<212> PRT
<213> Homo sapiens
<400> 3794
Leu Val Leu Trp Thr Ala Glu Glu Gln Gly Gly Val Gly Ala Phe Gln
1 5 10 15
Tyr Tyr Gln Leu His Lys
20
<210> 3795
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3795
Leu Val Asn Glu Val Thr Glu Phe Ala Lys
1 5 10
<210> 3796
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3796
Leu Val Asn Gly Gln Ser His Ile Ser Leu Ser Lys
1 5 10
<210> 3797
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3797
Leu Val Asn Gly Gln Ser His Ile Ser Leu Ser Lys Ala Glu Phe Gln
1 5 10 15
Asp Ala Leu Glu Lys
20
<210> 3798
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3798
Leu Val Asn Leu Lys
1 5
<210> 3799
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3799
Leu Val Asn Met Leu Asp Ala Val Gln Glu Asn Gln His Lys
1 5 10
<210> 3800
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3800
Leu Val Asn Val Val Leu Gly Ala His Asn Val Arg
1 5 10
<210> 3801
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3801
Leu Val Pro Phe Ala Thr Glu Leu His Glu Arg
1 5 10
<210> 3802
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3802
Leu Val Pro Gly Trp Thr Lys Pro Ile Thr Ile Gly Arg
1 5 10
<210> 3803
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3803
Leu Val Pro Asn Pro Asp Gln Lys
1 5
<210> 3804
<211> 34
<212> PRT
<213> Homo sapiens
<400> 3804
Leu Val Gln Ala Phe Gln Tyr Thr Asp Glu His Gly Glu Val Cys Pro
1 5 10 15
Ala Gly Trp Lys Pro Gly Ser Asp Thr Ile Lys Pro Asn Val Asp Asp
20 25 30
Ser Lys
<210> 3805
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3805
Leu Val Gln Gly Phe Met Pro His Phe Phe Arg
1 5 10
<210> 3806
<211> 22
<212> PRT
<213> Homo sapiens
<400> 3806
Leu Val Arg Pro Glu Val Asp Val Met Cys Thr Ala Phe His Asp Asn
1 5 10 15
Glu Glu Thr Phe Leu Lys
20
<210> 3807
<211> 23
<212> PRT
<213> Homo sapiens
<400> 3807
Leu Val Arg Pro Glu Val Asp Val Met Cys Thr Ala Phe His Asp Asn
1 5 10 15
Glu Glu Thr Phe Leu Lys Lys
20
<210> 3808
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3808
Leu Val Ser Ala Asn Arg
1 5
<210> 3809
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3809
Leu Val Ser Ala Gln Gln Lys
1 5
<210> 3810
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3810
Leu Val Ser Gly Trp Val Lys Pro Ile Ile Ile Gly Arg
1 5 10
<210> 3811
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3811
Leu Val Ser Gln Lys Pro Lys
1 5
<210> 3812
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3812
Leu Val Thr Asp Leu Thr Lys
1 5
<210> 3813
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3813
Leu Val Thr Glu Leu Arg
1 5
<210> 3814
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3814
Leu Val Thr Ser Lys
1 5
<210> 3815
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3815
Leu Val Thr Ser Lys Gly Asp Lys
1 5
<210> 3816
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3816
Leu Val Val Glu Glu Lys
1 5
<210> 3817
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3817
Leu Val Val Leu Pro Phe Pro Lys
1 5
<210> 3818
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3818
Leu Val Trp Glu Glu Ala Met Ser Arg
1 5
<210> 3819
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3819
Leu Val Tyr Ala Ile Phe Leu Lys
1 5
<210> 3820
<211> 22
<212> PRT
<213> Homo sapiens
<400> 3820
Leu Val Tyr His Leu Gly Leu Pro Phe Ser Phe Leu Thr Phe Pro Tyr
1 5 10 15
Val Glu Glu Ala Ile Lys
20
<210> 3821
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3821
Leu Trp Ala Tyr Leu Thr Ile Glu Gln Leu Leu Glu Lys
1 5 10
<210> 3822
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3822
Leu Trp Ala Tyr Leu Thr Ile Asn Gln Leu Leu Ala Glu Arg
1 5 10
<210> 3823
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3823
Leu Trp Ala Tyr Leu Thr Ile Gln Glu Leu Leu Ala Lys
1 5 10
<210> 3824
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3824
Leu Trp Ala Tyr Leu Thr Ile Gln Glu Leu Leu Ala Lys Arg
1 5 10
<210> 3825
<211> 26
<212> PRT
<213> Homo sapiens
<400> 3825
Leu Trp Ala Tyr Leu Thr Ile Gln Gln Leu Leu Glu Gln Thr Val Ser
1 5 10 15
Ala Ser Asp Ala Asp Gln Gln Ala Leu Arg
20 25
<210> 3826
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3826
Leu Trp Leu Gln Arg
1 5
<210> 3827
<211> 24
<212> PRT
<213> Homo sapiens
<400> 3827
Leu Trp Val Met Pro Asn His Gln Val Leu Leu Gly Pro Glu Glu Asp
1 5 10 15
Gln Asp His Ile Tyr His Pro Gln
20
<210> 3828
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3828
Leu Trp Trp Leu Asp Leu Lys
1 5
<210> 3829
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3829
Leu Tyr Ala Tyr His Leu Ser Arg
1 5
<210> 3830
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3830
Leu Tyr Gly Ser Glu Ala Phe Ala Thr Asp Phe Gln Asp Ser Ala Ala
1 5 10 15
Ala Lys
<210> 3831
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3831
Leu Tyr Gly Ser Glu Ala Phe Ala Thr Asp Phe Gln Asp Ser Ala Ala
1 5 10 15
Ala Lys Lys
<210> 3832
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3832
Leu Tyr His Ala Phe Ser Ala Met Lys
1 5
<210> 3833
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3833
Leu Tyr His Ala Phe Ser Ala Met Lys Lys
1 5 10
<210> 3834
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3834
Leu Tyr His Ser Glu Ala Phe Thr Val Asn Phe Gly Asp Thr Glu Glu
1 5 10 15
Ala Lys
<210> 3835
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3835
Leu Tyr His Ser Glu Ala Phe Thr Val Asn Phe Gly Asp Thr Glu Glu
1 5 10 15
Ala Lys Lys
<210> 3836
<211> 28
<212> PRT
<213> Homo sapiens
<400> 3836
Leu Tyr Leu Lys His Gln Met Asp Leu Val Ala Thr Leu Ser Gln Leu
1 5 10 15
Gly Leu Gln Glu Leu Phe Gln Ala Pro Asp Leu Arg
20 25
<210> 3837
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3837
Leu Tyr Leu Gln Met Ser Thr His Gly Lys
1 5 10
<210> 3838
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3838
Leu Tyr Leu Val Gln Gly Thr Gln Val Tyr Val Phe Leu Thr Lys
1 5 10 15
<210> 3839
<211> 26
<212> PRT
<213> Homo sapiens
<400> 3839
Leu Tyr Leu Val Gln Gly Thr Gln Val Tyr Val Phe Leu Thr Lys Gly
1 5 10 15
Gly Tyr Thr Leu Val Ser Gly Tyr Pro Lys
20 25
<210> 3840
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3840
Leu Tyr Pro Ile Ala Asn Gly Asn Asn Gln Ser Pro Val Asp Ile Lys
1 5 10 15
<210> 3841
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3841
Leu Tyr Gln His Ser Gln Gln Pro Gly Lys
1 5 10
<210> 3842
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3842
Leu Tyr Ser Ile Leu Gly Thr Thr Leu Lys Asp Glu Gly Lys
1 5 10
<210> 3843
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3843
Leu Tyr Ser Ile Leu Lys
1 5
<210> 3844
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3844
Leu Tyr Ser Leu Leu Lys
1 5
<210> 3845
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3845
Leu Tyr Ser Val His Arg Pro Val Lys
1 5
<210> 3846
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3846
Leu Tyr Ser Val Ser Tyr Leu Leu Lys
1 5
<210> 3847
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3847
Leu Tyr Val Glu Lys
1 5
<210> 3848
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3848
Leu Tyr Tyr Gly Asp Asp Glu Lys
1 5
<210> 3849
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3849
Leu Tyr Tyr Gly Asp Asp Glu Lys Tyr Phe Arg
1 5 10
<210> 3850
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3850
Met Ala Ala Ile Lys
1 5
<210> 3851
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3851
Met Ala Ala Leu Lys
1 5
<210> 3852
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3852
Met Ala Asp Glu Ala Gly Ser Glu Ala Asp His Glu Gly Thr His Ser
1 5 10 15
Thr Lys
<210> 3853
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3853
Met Ala Glu Ser Gly Tyr Asp Ile Ala Leu Leu Lys
1 5 10
<210> 3854
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3854
Met Ala Ile Thr Lys
1 5
<210> 3855
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3855
Met Ala Leu Glu Val Tyr Lys
1 5
<210> 3856
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3856
Met Ala Leu Glu Val Tyr Lys Leu Ser Leu Glu Ile Glu Gln Leu Glu
1 5 10 15
Leu Gln Arg
<210> 3857
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3857
Met Ala Leu Thr Lys
1 5
<210> 3858
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3858
Met Ala Pro Ser Phe Thr Ala Arg
1 5
<210> 3859
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3859
Met Ala Thr Asn Ala Ala Ala Gln Asn Ala Ile Lys Lys
1 5 10
<210> 3860
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3860
Met Ala Thr Thr Met Ile Gln Ser Lys
1 5
<210> 3861
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3861
Met Ala Val Gly Phe Met Leu Ala His Pro Tyr Gly Phe Thr Arg
1 5 10 15
<210> 3862
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3862
Met Cys Pro Gln Leu Gln Gln Tyr Glu Met His Gly Pro Glu Gly Leu
1 5 10 15
Arg
<210> 3863
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3863
Met Asp Glu Leu Arg Pro Leu Ile Pro Val Leu Glu Glu Tyr Lys
1 5 10 15
<210> 3864
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3864
Met Asp Glu Leu Arg Pro Leu Ile Pro Val Leu Glu Glu Tyr Lys Ala
1 5 10 15
Asp Ala Lys
<210> 3865
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3865
Met Asp Ile Leu Ser Tyr Met Arg
1 5
<210> 3866
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3866
Met Asp Met Thr Phe Ser Lys
1 5
<210> 3867
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3867
Met Asp Gln Leu Leu Leu Glu Lys
1 5
<210> 3868
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3868
Met Asp Val Phe Ser Gln Asn Met Phe Cys Ala Gly His Pro Ser Leu
1 5 10 15
Lys
<210> 3869
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3869
Met Asp Tyr Lys Gly Asp Ala Thr Val Phe Phe Ile Leu Pro Asn Gln
1 5 10 15
Gly Lys
<210> 3870
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3870
Met Asp Tyr Pro Lys
1 5
<210> 3871
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3871
Met Glu Glu Met Gly Ser Arg
1 5
<210> 3872
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3872
Met Glu Glu Val Glu Ala Met Leu Leu Pro Glu Thr Leu Lys
1 5 10
<210> 3873
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3873
Met Glu Glu Val Glu Ala Met Leu Leu Pro Glu Thr Leu Lys Arg
1 5 10 15
<210> 3874
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3874
Met Glu Ile Leu His Pro Gly Lys
1 5
<210> 3875
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3875
Met Glu Ile Gln Glu Ile Gln Leu Lys
1 5
<210> 3876
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3876
Met Glu Leu Glu Arg Pro Gly Gly Asn Glu Ile Thr Arg
1 5 10
<210> 3877
<211> 29
<212> PRT
<213> Homo sapiens
<400> 3877
Met Glu Leu Glu Arg Pro Gly Gly Asn Glu Ile Thr Arg Gly Gly Ser
1 5 10 15
Thr Ser Tyr Gly Thr Gly Ser Glu Thr Glu Ser Pro Arg
20 25
<210> 3878
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3878
Met Glu Leu Gln Glu Ile Gln Leu Lys
1 5
<210> 3879
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3879
Met Glu Pro Phe His Phe Lys
1 5
<210> 3880
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3880
Met Glu Pro Phe His Phe Lys Asn Ser Val Ile Lys
1 5 10
<210> 3881
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3881
Met Glu Ser Leu Gly Ile Thr Ser Arg
1 5
<210> 3882
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3882
Met Phe Glu Glu Leu Lys
1 5
<210> 3883
<211> 42
<212> PRT
<213> Homo sapiens
<400> 3883
Met Phe Gly Asn Leu Gln Gly Leu Thr Met His Val Gly Asp Glu Val
1 5 10 15
Asn Trp Tyr Leu Met Gly Met Gly Asn Glu Ile Asp Leu His Thr Val
20 25 30
His Phe His Gly His Ser Phe Gln Tyr Lys
35 40
<210> 3884
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3884
Met Phe Leu His Val Lys
1 5
<210> 3885
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3885
Met Phe Leu His Val Lys Gly Glu Ile His Leu Gly Arg
1 5 10
<210> 3886
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3886
Met Phe Leu Ser Phe Pro Thr Thr Lys
1 5
<210> 3887
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3887
Met Phe Gln Glu Ile Val His Lys
1 5
<210> 3888
<211> 24
<212> PRT
<213> Homo sapiens
<400> 3888
Met Phe Gln Asn Phe Pro Thr Glu Leu Leu Leu Ser Leu Ala Val Glu
1 5 10 15
Pro Leu Thr Ala Asn Phe His Lys
20
<210> 3889
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3889
Met Phe Thr Thr Ala Pro Asp Gln Val Asp Lys
1 5 10
<210> 3890
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3890
Met Phe Thr Thr Ala Pro Asp Gln Val Asp Lys Glu Asp Glu Asp Phe
1 5 10 15
Gln Glu Ser Asn Lys
20
<210> 3891
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3891
Met Phe Tyr Ile Lys Pro Ile Lys
1 5
<210> 3892
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3892
Met Gly Asp His Leu Ala Leu Glu Asp Tyr Leu Thr Thr Asp Leu Val
1 5 10 15
Glu Thr Trp Leu Arg
20
<210> 3893
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3893
Met Gly Asp His Leu Thr Asn Leu His Arg
1 5 10
<210> 3894
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3894
Met Gly Phe Val Asp Asn Lys Arg
1 5
<210> 3895
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3895
Met Gly His Ala Gly Ala Ile Ile Ala Gly Gly Lys
1 5 10
<210> 3896
<211> 23
<212> PRT
<213> Homo sapiens
<400> 3896
Met Gly Ile Gln His Ala Tyr Ser Glu Asn Ala Asp Phe Ser Gly Leu
1 5 10 15
Thr Glu Asp Asn Gly Leu Lys
20
<210> 3897
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3897
Met Gly Leu Ala Phe Glu Ser Thr Lys
1 5
<210> 3898
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3898
Met Gly Asn Phe Pro Trp Gln Val Phe Thr Asn Ile His Gly Arg
1 5 10 15
<210> 3899
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3899
Met Gly Asn Leu His Thr Trp Asp Gly Pro Leu Pro Pro Ser Trp His
1 5 10 15
Ile Lys
<210> 3900
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3900
Met Gly Pro Thr Glu Leu Leu Ile Glu Met Glu Asp Trp Lys
1 5 10
<210> 3901
<211> 17
<212> PRT
<213> Homo sapiens
<400> 3901
Met Gly Pro Thr Glu Leu Leu Ile Glu Met Glu Asp Trp Lys Gly Asp
1 5 10 15
Lys
<210> 3902
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3902
Met Gly Pro Val Thr Ser Ala His Val Gly Thr Tyr Arg
1 5 10
<210> 3903
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3903
Met His Ala Ile Asn Gly Arg
1 5
<210> 3904
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3904
Met His Ala Pro Pro Ile Asn Met Glu Ser Val His Met Lys
1 5 10
<210> 3905
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3905
Met His Glu Gly Asp Glu Gly Pro Gly His His His Lys Pro Gly Leu
1 5 10 15
Gly Glu Gly Thr Pro
20
<210> 3906
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3906
Met His Leu Tyr Gly Leu His Glu Gly Gln Arg
1 5 10
<210> 3907
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3907
Met His Ser Met Asn Gly Phe Met Tyr Gly Asn Gln Pro Gly Leu Thr
1 5 10 15
Met Cys Lys
<210> 3908
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3908
Met His Val Leu His Cys Gln Gly Arg
1 5
<210> 3909
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3909
Met Ile Glu Gln Met Leu Lys
1 5
<210> 3910
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3910
Met Ile Lys Pro Phe Phe His Ser Leu Ser Glu Lys
1 5 10
<210> 3911
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3911
Met Ile Leu Glu Leu Phe Ser Lys
1 5
<210> 3912
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3912
Met Ile Tyr Ala Ser Ser Lys
1 5
<210> 3913
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3913
Met Lys Asp Thr Asp Ser Glu Glu Glu Ile Arg
1 5 10
<210> 3914
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3914
Met Lys Phe Ala Cys Tyr Tyr Pro Arg
1 5
<210> 3915
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3915
Met Lys Gly Leu Ile Asp Glu Val Asn Gln Asp Phe Thr Asn Arg
1 5 10 15
<210> 3916
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3916
Met Lys Pro Val Pro Asp Leu Val Pro Gly Asn Phe Lys
1 5 10
<210> 3917
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3917
Met Lys Pro Val Pro Asp Leu Val Pro Gly Asn Phe Lys Ser Gln Leu
1 5 10 15
Gln Lys
<210> 3918
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3918
Met Lys Gln Thr Val Glu Ala Met Lys
1 5
<210> 3919
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3919
Met Lys Tyr Trp Gly Val Ala Ser Phe Leu Gln Lys
1 5 10
<210> 3920
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3920
Met Leu Asp Ala Glu Asp Ile Val Gly Thr Ala Arg Pro Asp Glu Lys
1 5 10 15
<210> 3921
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3921
Met Leu Glu Glu Ile Met Lys
1 5
<210> 3922
<211> 20
<212> PRT
<213> Homo sapiens
<400> 3922
Met Leu Glu Glu Ile Met Lys Tyr Glu Ala Ser Ile Leu Thr His Asp
1 5 10 15
Ser Ser Ile Arg
20
<210> 3923
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3923
Met Leu Glu Val Pro Tyr Val Asp Arg
1 5
<210> 3924
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3924
Met Leu Phe Asp Lys
1 5
<210> 3925
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3925
Met Leu Phe Asp Lys Asn Gly Asn Met Ala Gly Ile Ser Asp Gln Arg
1 5 10 15
<210> 3926
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3926
Met Leu His Ala Cys Thr Ser Glu Gly Ser Ala His Arg
1 5 10
<210> 3927
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3927
Met Leu Ile Thr Ile Leu Gly Thr Val Lys Pro Asn Ala Asn Arg
1 5 10 15
<210> 3928
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3928
Met Leu Gln Ile Thr Asn Thr Gly Phe Glu Met Lys
1 5 10
<210> 3929
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3929
Met Leu Thr Glu Leu Glu Lys
1 5
<210> 3930
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3930
Met Leu Thr Pro Glu His Val Phe Ile His Pro Gly Trp Lys
1 5 10
<210> 3931
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3931
Met Met Ala Val Ala Ala Asp Thr Leu Gln Arg
1 5 10
<210> 3932
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3932
Met Met Pro His Phe Gln Lys
1 5
<210> 3933
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3933
Met Asn Phe Lys Gln Glu Leu Asn Gly Asn Thr Lys
1 5 10
<210> 3934
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3934
Met Asn Phe Arg Pro Gly Val Leu Ser Ser Arg
1 5 10
<210> 3935
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3935
Met Asn Leu Ala Ser Glu Pro Gln Glu Val Leu His Ile Gly Ser Ala
1 5 10 15
His Asn Arg
<210> 3936
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3936
Met Asn Leu Ser Arg Leu Lys
1 5
<210> 3937
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3937
Met Asn Leu Tyr Gly Phe His Gly Gly Gln Arg
1 5 10
<210> 3938
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3938
Met Asn Met Thr Ala Tyr Asn Lys
1 5
<210> 3939
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3939
Met Asn Thr Val Ile Ala Ala Leu Ser Arg
1 5 10
<210> 3940
<211> 22
<212> PRT
<213> Homo sapiens
<400> 3940
Met Asn Val Ala Pro Ala Cys Leu Pro Glu Arg Asp Trp Ala Glu Ser
1 5 10 15
Thr Leu Met Thr Gln Lys
20
<210> 3941
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3941
Met Pro Glu Ile Asn Ile Lys
1 5
<210> 3942
<211> 26
<212> PRT
<213> Homo sapiens
<400> 3942
Met Pro Ile Thr Tyr Asp Asn Gly Phe Leu Phe Ile His Thr Asp Lys
1 5 10 15
Pro Val Tyr Thr Pro Asp Gln Ser Val Lys
20 25
<210> 3943
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3943
Met Pro Pro Ser His Gln Leu Asp His Ser Lys
1 5 10
<210> 3944
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3944
Met Gln His Leu Ile Ala Arg
1 5
<210> 3945
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3945
Met Gln Ile Leu Glu Gly Leu Gly Leu Asn Leu Gln Lys
1 5 10
<210> 3946
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3946
Met Gln Gln Val Glu Asn Gly Leu Ser Glu Lys
1 5 10
<210> 3947
<211> 9
<212> PRT
<213> Homo sapiens
<400> 3947
Met Arg Asp Val Val Leu Phe Glu Lys
1 5
<210> 3948
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3948
Met Arg Glu Ile Glu Glu Val Leu Thr Pro Glu Met Leu Met Arg
1 5 10 15
<210> 3949
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3949
Met Arg Glu Trp Phe Ser Glu Thr Phe Gln Lys
1 5 10
<210> 3950
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3950
Met Arg Ile His Leu Lys
1 5
<210> 3951
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3951
Met Arg Met Thr Ser Ser Pro Val Thr Gly Gly Lys
1 5 10
<210> 3952
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3952
Met Arg Pro Ser Thr Asp Thr Ile Thr Val Met Val Glu Asn Ser His
1 5 10 15
Gly Leu Arg
<210> 3953
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3953
Met Ser Ala Glu Ile Asn Glu Ile Ile Arg
1 5 10
<210> 3954
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3954
Met Ser Ala Gln Thr His Gly Leu Leu Gly Gln Phe Phe Gln Pro Phe
1 5 10 15
Asp Phe Lys
<210> 3955
<211> 21
<212> PRT
<213> Homo sapiens
<400> 3955
Met Ser Ala Val Glu Gly Ile Cys Thr Ser Glu Ser Pro Val Ile Asp
1 5 10 15
His Gln Gly Thr Lys
20
<210> 3956
<211> 24
<212> PRT
<213> Homo sapiens
<400> 3956
Met Ser Glu Asn Ile Pro Asn Glu Val Tyr Ala Leu Gly Ala Phe Asp
1 5 10 15
Gly Leu His Thr Val Glu Gly Arg
20
<210> 3957
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3957
Met Ser Glu Ser Gly Phe Lys
1 5
<210> 3958
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3958
Met Ser Gly Met Lys
1 5
<210> 3959
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3959
Met Ser Leu Asn Gly Gln Arg
1 5
<210> 3960
<211> 31
<212> PRT
<213> Homo sapiens
<400> 3960
Met Ser Leu Ser Ser Phe Ser Val Asn Arg Pro Phe Leu Phe Phe Ile
1 5 10 15
Phe Glu Asp Thr Thr Gly Leu Pro Leu Phe Val Gly Ser Val Arg
20 25 30
<210> 3961
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3961
Met Ser Ser Ile Asn Ala Asp Phe Ala Phe Asn Leu Tyr Arg
1 5 10
<210> 3962
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3962
Met Ser Ser Ser Val Glu Gln Lys
1 5
<210> 3963
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3963
Met Thr Ala Gln Pro Gly Arg Pro Phe Gly Ser Thr Lys
1 5 10
<210> 3964
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3964
Met Thr Ala Ser Phe His Gln Thr Tyr Arg
1 5 10
<210> 3965
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3965
Met Thr Gly Leu Val Asp Glu Ala Ile Asp Thr Lys
1 5 10
<210> 3966
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3966
Met Thr Leu Asp Asp Phe Arg
1 5
<210> 3967
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3967
Met Thr Met Asp Lys
1 5
<210> 3968
<211> 14
<212> PRT
<213> Homo sapiens
<400> 3968
Met Thr Ser Asn Phe Pro Val Asp Leu Ser Asp Tyr Pro Lys
1 5 10
<210> 3969
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3969
Met Val Ala Asn Asp Ile Ala Lys
1 5
<210> 3970
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3970
Met Val Glu Thr Thr Ala Tyr Ala Leu Leu Thr Ser Leu Asn Leu Lys
1 5 10 15
<210> 3971
<211> 18
<212> PRT
<213> Homo sapiens
<400> 3971
Met Val Gly Gly Ile Ala Gln Ile Ile Ala Ala Gln Glu Glu Met Leu
1 5 10 15
Arg Lys
<210> 3972
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3972
Met Val Leu Leu Glu Gln Leu Phe Leu Asp His Asn Ala Leu Arg
1 5 10 15
<210> 3973
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3973
Met Val Asn His Phe Ile Ala Glu Phe Lys
1 5 10
<210> 3974
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3974
Met Val Gln Gly Lys
1 5
<210> 3975
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3975
Met Val Ser Gly Phe Ile Pro Leu Lys Pro Thr Val Lys
1 5 10
<210> 3976
<211> 7
<212> PRT
<213> Homo sapiens
<400> 3976
Met Val Thr Ser Glu Ser Lys
1 5
<210> 3977
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3977
Met Val Val Glu Ser Ala Tyr Glu Val Ile Lys
1 5 10
<210> 3978
<211> 24
<212> PRT
<213> Homo sapiens
<400> 3978
Met Val Val Asn Glu Gly Ser Asp Gly Gly Gln Ser Val Tyr His Val
1 5 10 15
His Leu His Val Leu Gly Gly Arg
20
<210> 3979
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3979
Met Val Val Val Ala Ala Ala Pro Asn Pro Ala Asp Gly Thr Pro Lys
1 5 10 15
<210> 3980
<211> 8
<212> PRT
<213> Homo sapiens
<400> 3980
Met Tyr Glu Gln Glu Trp Val Arg
1 5
<210> 3981
<211> 15
<212> PRT
<213> Homo sapiens
<400> 3981
Met Tyr Phe Asp Ala Val Gln Ala Ile Glu Thr His Leu Ile Arg
1 5 10 15
<210> 3982
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3982
Met Tyr Leu Glu Lys
1 5
<210> 3983
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3983
Met Tyr Leu Gly Tyr Glu Tyr Val Thr Ala Ile Arg
1 5 10
<210> 3984
<211> 5
<212> PRT
<213> Homo sapiens
<400> 3984
Met Tyr Leu Gln Lys
1 5
<210> 3985
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3985
Met Tyr Val Ala Val Trp Thr Pro Tyr Gly Val Leu Arg
1 5 10
<210> 3986
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3986
Met Tyr Tyr Ser Ala Val Asp Pro Thr Lys
1 5 10
<210> 3987
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3987
Asn Ala Ala Glu Asn Gly Ala Ile Gln Asn Leu Ile Lys
1 5 10
<210> 3988
<211> 24
<212> PRT
<213> Homo sapiens
<400> 3988
Asn Ala Ala Glu Asn Gly Ala Ile Gln Asn Leu Ile Lys Glu Glu Ala
1 5 10 15
Phe Leu Gly Ile Thr Asp Glu Lys
20
<210> 3989
<211> 19
<212> PRT
<213> Homo sapiens
<400> 3989
Asn Ala Asp Leu Gln Val Leu Lys Pro Glu Pro Glu Leu Val Tyr Glu
1 5 10 15
Asp Leu Arg
<210> 3990
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3990
Asn Ala Asp Tyr Ser Tyr Ser Val Trp Lys
1 5 10
<210> 3991
<211> 24
<212> PRT
<213> Homo sapiens
<400> 3991
Asn Ala Asp Tyr Ser Tyr Ser Val Trp Lys Gly Gly Ser Ala Ser Thr
1 5 10 15
Trp Leu Thr Ala Phe Ala Leu Arg
20
<210> 3992
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3992
Asn Ala Glu Glu Leu Lys
1 5
<210> 3993
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3993
Asn Ala His Gly Glu Glu Lys Glu Asn Leu Thr Ala Arg
1 5 10
<210> 3994
<211> 6
<212> PRT
<213> Homo sapiens
<400> 3994
Asn Ala His Leu Lys Lys
1 5
<210> 3995
<211> 16
<212> PRT
<213> Homo sapiens
<400> 3995
Asn Ala Ile His Thr Phe Val Gln Ser Gly Ser His Leu Ala Ala Arg
1 5 10 15
<210> 3996
<211> 12
<212> PRT
<213> Homo sapiens
<400> 3996
Asn Ala Ile Trp Ile Asp Cys Gly Ile His Ala Arg
1 5 10
<210> 3997
<211> 10
<212> PRT
<213> Homo sapiens
<400> 3997
Asn Ala Leu Ala Leu Phe Val Leu Pro Lys
1 5 10
<210> 3998
<211> 11
<212> PRT
<213> Homo sapiens
<400> 3998
Asn Ala Leu Phe Cys Leu Glu Ser Ala Trp Lys
1 5 10
<210> 3999
<211> 13
<212> PRT
<213> Homo sapiens
<400> 3999
Asn Ala Leu Gly Ala Ile His His Thr Ile Ser Val Arg
1 5 10
<210> 4000
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4000
Asn Ala Leu Gln Asn Ile Ile Leu Tyr His Leu Thr Pro Gly Val Phe
1 5 10 15
Ile Gly Lys
<210> 4001
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4001
Asn Ala Leu Thr Gly Leu Pro Pro Gly Leu Phe Gln Ala Ser Ala Thr
1 5 10 15
Leu Asp Thr Leu Val Leu Lys
20
<210> 4002
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4002
Asn Ala Leu Trp His Thr Gly Asp Thr Glu Ser Gln Val Arg
1 5 10
<210> 4003
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4003
Asn Ala Leu Trp His Thr Gly Asn Thr Pro Gly Gln Val Arg
1 5 10
<210> 4004
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4004
Asn Ala Pro Ala Ile Ile Phe Ile Asp Glu Leu Asp Ala Ile Ala Pro
1 5 10 15
Lys
<210> 4005
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4005
Asn Ala Pro Thr Pro Gln Glu Phe Arg
1 5
<210> 4006
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4006
Asn Ala Val Pro Pro Val Ile His Ser Pro Asn Asp His Val Val Tyr
1 5 10 15
Glu Lys
<210> 4007
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4007
Asn Ala Val Val Gln Gly Leu Glu Gln Pro His Gly Leu Val Val His
1 5 10 15
Pro Leu Arg
<210> 4008
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4008
Asn Asp Glu Met Gln Glu Thr Pro Asn Arg
1 5 10
<210> 4009
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4009
Asn Asp Phe Thr Trp Phe Lys
1 5
<210> 4010
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4010
Asn Asp Leu Ile Ser Ala Thr Lys
1 5
<210> 4011
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4011
Asn Asp Leu Val Glu Ala Leu Lys
1 5
<210> 4012
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4012
Asn Asp Asn Asp Asn Ile Phe Leu Ser Pro Leu Ser Ile Ser Thr Ala
1 5 10 15
Phe Ala Met Thr Lys
20
<210> 4013
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4013
Asn Asp Pro Phe Lys
1 5
<210> 4014
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4014
Asn Asp Tyr Leu Asp Ile Tyr Ala Ile Gly Val Gly Lys
1 5 10
<210> 4015
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4015
Asn Glu Ala Asp Glu Leu Arg Lys
1 5
<210> 4016
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4016
Asn Glu Cys Phe Leu Gln His Lys Asp Asp Asn Pro Asn Leu Pro Arg
1 5 10 15
<210> 4017
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4017
Asn Glu Asp Ser Leu Val Phe Val Gln Thr Asp Lys
1 5 10
<210> 4018
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4018
Asn Glu Asp Ser Leu Val Phe Val Gln Thr Asp Lys Ser Ile Tyr Lys
1 5 10 15
Pro Gly Gln Thr Val Lys
20
<210> 4019
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4019
Asn Glu Ile Trp Tyr Arg
1 5
<210> 4020
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4020
Asn Glu Leu Glu Ser Tyr Ala Tyr Ser Leu Lys
1 5 10
<210> 4021
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4021
Asn Glu Leu Ile Pro Leu Ile Tyr Leu Glu Asn Pro Arg Arg
1 5 10
<210> 4022
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4022
Asn Glu Leu Val Gln Lys
1 5
<210> 4023
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4023
Asn Glu Asn Thr Phe Leu Asp Leu Thr Val Gln Gln Ile Glu His Leu
1 5 10 15
Asn Lys
<210> 4024
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4024
Asn Phe Ala Thr Ser Asn Lys
1 5
<210> 4025
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4025
Asn Phe Ala Thr Ser Asn Lys Met Asp Met Thr Phe Ser Lys
1 5 10
<210> 4026
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4026
Asn Phe Glu Ile Thr Ile Lys
1 5
<210> 4027
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4027
Asn Phe Phe Asn Pro Pro Ile Ile Ser Arg
1 5 10
<210> 4028
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4028
Asn Phe Gly Tyr Thr Leu Arg
1 5
<210> 4029
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4029
Asn Phe Lys Asn Phe Glu Ile Thr Ile Lys
1 5 10
<210> 4030
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4030
Asn Phe Leu Ala Phe Ile Gln His Leu Arg
1 5 10
<210> 4031
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4031
Asn Phe Pro Asp Leu Asn Thr Tyr Ile Tyr Tyr Asn Glu Lys
1 5 10
<210> 4032
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4032
Asn Phe Pro Ser Pro Val Asp Ala Ala Phe Arg
1 5 10
<210> 4033
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4033
Asn Phe Pro Ser Pro Val Asp Ala Ala Phe Arg Gln Gly His Asn Ser
1 5 10 15
Val Phe Leu Ile Lys
20
<210> 4034
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4034
Asn Phe Ser Asp Asn Gln Leu Gln Glu Gly Lys
1 5 10
<210> 4035
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4035
Asn Phe Thr Glu Val His Pro Asp Tyr Gly Ser His Ile Gln Ala Leu
1 5 10 15
Leu Asp Lys
<210> 4036
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4036
Asn Phe Thr Val Glu Lys
1 5
<210> 4037
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4037
Asn Phe Val Ala Ser His Ile Ala Asn Ile Leu Asn Ser Glu Glu Leu
1 5 10 15
Asp Ile Gln Asp Leu Lys
20
<210> 4038
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4038
Asn Phe Val Ala Ser His Ile Ala Asn Ile Leu Asn Ser Glu Glu Leu
1 5 10 15
Asp Ile Gln Asp Leu Lys Lys
20
<210> 4039
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4039
Asn Phe Val Val Val Met Val Thr Lys Pro Lys
1 5 10
<210> 4040
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4040
Asn Gly Ala Ile His Ile Phe Arg
1 5
<210> 4041
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4041
Asn Gly Ala Val Thr His Ile Lys
1 5
<210> 4042
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4042
Asn Gly Asp Leu Asp Glu Val Lys
1 5
<210> 4043
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4043
Asn Gly Asp Leu Asp Glu Val Lys Asp Tyr Val Ala Lys
1 5 10
<210> 4044
<211> 32
<212> PRT
<213> Homo sapiens
<400> 4044
Asn Gly Glu Ser Val Lys Leu His Leu Glu Thr Asp Ser Leu Ala Leu
1 5 10 15
Val Ala Leu Gly Ala Leu Asp Thr Ala Leu Tyr Ala Ala Gly Ser Lys
20 25 30
<210> 4045
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4045
Asn Gly Phe Val Met Leu Ser Asn Lys
1 5
<210> 4046
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4046
Asn Gly Phe Val Met Leu Ser Asn Lys Lys
1 5 10
<210> 4047
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4047
Asn Gly Phe Tyr Pro Ala Thr Arg
1 5
<210> 4048
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4048
Asn Gly Ile Thr Cys Gln Lys
1 5
<210> 4049
<211> 24
<212> PRT
<213> Homo sapiens
<400> 4049
Asn Gly Lys Val Gly Leu Ser Gly Met Ala Ile Ala Asp Val Thr Leu
1 5 10 15
Leu Ser Gly Phe His Ala Leu Arg
20
<210> 4050
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4050
Asn Gly Leu Tyr Ala Asp Asn Asp Asn Asp Ser Thr Phe Thr Gly Phe
1 5 10 15
Leu Leu Tyr His Asp Thr Asn
20
<210> 4051
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4051
Asn Gly Met Leu His Gly Asp Lys
1 5
<210> 4052
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4052
Asn Gly Asn Met Ala Gly Ile Ser Asp Gln Arg
1 5 10
<210> 4053
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4053
Asn Gly Pro Glu Gln Trp Ser Lys
1 5
<210> 4054
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4054
Asn Gly Gln Val Glu Ile Lys
1 5
<210> 4055
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4055
Asn Gly Gln Trp Ser Glu Pro Pro Lys
1 5
<210> 4056
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4056
Asn Gly Arg Pro Leu Lys Glu Glu Lys
1 5
<210> 4057
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4057
Asn Gly Arg Val Glu Ile Ile Ala Asn Asp Gln Gly Asn Arg
1 5 10
<210> 4058
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4058
Asn Gly Ser Leu Phe Ala Phe Arg
1 5
<210> 4059
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4059
Asn Gly Thr Gly His Gly Asn Ser Thr His His Gly Pro Glu Tyr Met
1 5 10 15
Arg
<210> 4060
<211> 45
<212> PRT
<213> Homo sapiens
<400> 4060
Asn Gly Thr Gly His Gly Asn Ser Thr His His Gly Pro Glu Tyr Met
1 5 10 15
Arg Cys Ser Pro His Leu Val Leu Ser Ala Leu Thr Ser Asp Asn His
20 25 30
Gly Ala Thr Tyr Ala Phe Ser Gly Thr His Tyr Trp Arg
35 40 45
<210> 4061
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4061
Asn Gly Val Ala Gln Glu Pro Val His Leu Asp Ser Pro Ala Ile Lys
1 5 10 15
<210> 4062
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4062
Asn Gly Val Gly Val Leu Ile Trp Lys
1 5
<210> 4063
<211> 26
<212> PRT
<213> Homo sapiens
<400> 4063
Asn Gly Val Asn Val Ile Ser Gly Pro Ile Phe Asp Tyr Asp Tyr Asp
1 5 10 15
Gly Leu His Asp Thr Glu Asp Lys Ile Lys
20 25
<210> 4064
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4064
Asn Gly Tyr Ala Tyr His Lys
1 5
<210> 4065
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4065
Asn His Ile Ile Lys Asp Gln Leu Ala Ser Lys
1 5 10
<210> 4066
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4066
Asn His Leu Gln Leu Glu Gly Leu Phe Phe Thr Asn Gly Glu His Thr
1 5 10 15
Ser Lys
<210> 4067
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4067
Asn His Met Gln Tyr Glu Ile Val Ile Lys
1 5 10
<210> 4068
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4068
Asn His Asn Ala Leu Leu Ala Ser Leu Thr Thr Gln Lys
1 5 10
<210> 4069
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4069
Asn His Gln Leu Ile Val Thr Arg
1 5
<210> 4070
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4070
Asn His Gln Ser Ser Tyr Gln Thr Arg
1 5
<210> 4071
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4071
Asn Ile Ala Ala Phe Gly Gly Asn Pro Lys
1 5 10
<210> 4072
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4072
Asn Ile Ala Ser Arg
1 5
<210> 4073
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4073
Asn Ile Asp Asn Pro Ala Leu Ala Asp Ile Tyr Thr Glu His Ala His
1 5 10 15
Gln Val Val Val Ala Lys
20
<210> 4074
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4074
Asn Ile Glu Lys Ile Ser Met Leu Glu Lys
1 5 10
<210> 4075
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4075
Asn Ile Glu Thr Ile Ile Asn Thr Phe His Gln Tyr Ser Val Lys
1 5 10 15
<210> 4076
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4076
Asn Ile Phe Asn Phe Lys
1 5
<210> 4077
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4077
Asn Ile Ile Phe Val Glu Thr Ser Phe Thr Thr Leu Glu Thr Arg
1 5 10 15
<210> 4078
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4078
Asn Ile Ile His Gly Ser Asp Ser Val Lys
1 5 10
<210> 4079
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4079
Asn Ile Ile Leu Glu Glu Gly Lys
1 5
<210> 4080
<211> 28
<212> PRT
<213> Homo sapiens
<400> 4080
Asn Ile Ile Leu Glu Glu Gly Lys Glu Ile Leu Val Gly Asp Val Gly
1 5 10 15
Gln Thr Val Asp Asp Pro Tyr Ala Thr Phe Val Lys
20 25
<210> 4081
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4081
Asn Ile Ile Leu Pro Val Tyr Asp Lys
1 5
<210> 4082
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4082
Asn Ile Leu Asp Arg
1 5
<210> 4083
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4083
Asn Ile Leu Asp Arg Gln Asp Pro Pro Ser Val Val Val Thr Ser His
1 5 10 15
Gln Ala Pro Gly Glu Lys
20
<210> 4084
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4084
Asn Ile Leu Asp Ser Lys Pro Thr Ala Asn Lys Lys
1 5 10
<210> 4085
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4085
Asn Ile Leu Phe Val Ile Asp Val Ser Gly Ser Met Trp Gly Val Lys
1 5 10 15
<210> 4086
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4086
Asn Ile Leu Thr Ser Asn Asn Ile Asp Val Lys
1 5 10
<210> 4087
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4087
Asn Ile Asn Gln Ile Lys
1 5
<210> 4088
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4088
Asn Ile Asn Gln Leu Lys
1 5
<210> 4089
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4089
Asn Ile Pro Thr Val Asn Glu Asn Leu Glu Asn Tyr Tyr Leu Glu Val
1 5 10 15
Asn Gln Leu Glu Lys
20
<210> 4090
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4090
Asn Ile Gln Glu Tyr Leu Ser Ile Leu Thr Asp Pro Asp Gly Lys
1 5 10 15
<210> 4091
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4091
Asn Ile Gln Glu Tyr Leu Ser Ile Leu Thr Asp Pro Asp Gly Lys Gly
1 5 10 15
Lys
<210> 4092
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4092
Asn Ile Gln Ser Leu Glu Val Ile Gly Lys
1 5 10
<210> 4093
<211> 27
<212> PRT
<213> Homo sapiens
<400> 4093
Asn Ile Ser Asp Gly Phe Asp Gly Ile Pro Asp Asn Val Asp Ala Ala
1 5 10 15
Leu Ala Leu Pro Ala His Ser Tyr Ser Gly Arg
20 25
<210> 4094
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4094
Asn Ile Ser Phe Asn Asp Lys
1 5
<210> 4095
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4095
Asn Ile Val Thr Pro Arg
1 5
<210> 4096
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4096
Asn Lys Glu Asp Cys Val Glu Ile Tyr Ile Lys
1 5 10
<210> 4097
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4097
Asn Lys Phe Asp Pro Ser Leu Thr Gln Arg
1 5 10
<210> 4098
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4098
Asn Lys Phe Glu Glu Ala Glu Arg
1 5
<210> 4099
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4099
Asn Lys Gly Pro Thr Val Lys
1 5
<210> 4100
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4100
Asn Lys Leu Asp Phe Leu Arg Pro Tyr Thr Val Pro Asn Lys
1 5 10
<210> 4101
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4101
Asn Lys Leu Glu Gly Leu Glu Asp Ala Leu Gln Lys
1 5 10
<210> 4102
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4102
Asn Lys Leu Asn Asp Leu Glu Asp Ala Leu Gln Gln Ala Lys
1 5 10
<210> 4103
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4103
Asn Lys Leu Asn Asp Leu Glu Glu Ala Leu Gln Gln Ala Lys
1 5 10
<210> 4104
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4104
Asn Lys Leu Thr Gln Ser Lys
1 5
<210> 4105
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4105
Asn Lys Pro Glu Trp Phe Phe Lys
1 5
<210> 4106
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4106
Asn Lys Pro Gly Val Tyr Thr Asp Val Ala Tyr Tyr Leu Ala Trp Ile
1 5 10 15
Arg
<210> 4107
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4107
Asn Lys Pro Gly Val Tyr Thr Lys
1 5
<210> 4108
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4108
Asn Lys Tyr Glu Asp Glu Ile Asn Lys
1 5
<210> 4109
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4109
Asn Lys Tyr Gly Met Val Ala Gln Val Thr Gln Thr Leu Lys
1 5 10
<210> 4110
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4110
Asn Leu Ala Ser Arg
1 5
<210> 4111
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4111
Asn Leu Ala Ser Arg Pro Tyr Ser Leu His Ala His Gly Leu Ser Tyr
1 5 10 15
Glu Lys
<210> 4112
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4112
Asn Leu Ala Ser Arg Pro Tyr Thr Phe His Ser His Gly Ile Thr Tyr
1 5 10 15
Tyr Lys
<210> 4113
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4113
Asn Leu Ala Val Ser Gln Val Val His Lys
1 5 10
<210> 4114
<211> 29
<212> PRT
<213> Homo sapiens
<400> 4114
Asn Leu Ala Val Ser Gln Val Val His Lys Ala Val Leu Asp Val Phe
1 5 10 15
Glu Glu Gly Thr Glu Ala Ser Ala Ala Thr Ala Val Lys
20 25
<210> 4115
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4115
Asn Leu Cys Glu Ala Met Glu Asn Phe Met Gln Gln Leu Lys
1 5 10
<210> 4116
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4116
Asn Leu Asp Glu Asn Tyr Cys Arg
1 5
<210> 4117
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4117
Asn Leu Asp Gly Ile Ser His Ala Pro Asn Ala Val Lys
1 5 10
<210> 4118
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4118
Asn Leu Asp Ile Glu Arg Pro Thr Tyr Thr Asn Leu Asn Arg
1 5 10
<210> 4119
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4119
Asn Leu Asp Leu Asp Ser Ile Ile Ala Glu Val Lys
1 5 10
<210> 4120
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4120
Asn Leu Asp Ser Asn Ala Val Val Ile Met Val Asn Tyr Ile Phe Phe
1 5 10 15
Lys
<210> 4121
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4121
Asn Leu Glu Leu Gly Leu Thr Gln Gly Ser Phe Ala Phe Ile His Lys
1 5 10 15
<210> 4122
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4122
Asn Leu Phe Arg Pro Ser Leu Pro Ser Ser Trp Lys
1 5 10
<210> 4123
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4123
Asn Leu Phe Tyr Leu Pro His Gly Leu Ser Ile Asp Lys
1 5 10
<210> 4124
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4124
Asn Leu Gly Thr Ala Leu Ala Glu Leu Arg
1 5 10
<210> 4125
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4125
Asn Leu His Asp Leu Asp Val Ser Asp Asn Gln Leu Glu Arg
1 5 10
<210> 4126
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4126
Asn Leu His Phe Leu Thr Thr Gln Glu Asp Tyr Thr Leu Lys
1 5 10
<210> 4127
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4127
Asn Leu Ile Ala Ala Val Ala Pro Gly Ala Phe Leu Gly Leu Lys
1 5 10 15
<210> 4128
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4128
Asn Leu Ile Ala Val Leu Gly Glu His Asp Leu Ser Glu His Asp Gly
1 5 10 15
Asp Glu Gln Ser Arg
20
<210> 4129
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4129
Asn Leu Ile Ala Val Leu Gly Glu His Asp Leu Ser Glu His Asp Gly
1 5 10 15
Asp Glu Gln Ser Arg Arg
20
<210> 4130
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4130
Asn Leu Ile Asp Arg
1 5
<210> 4131
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4131
Asn Leu Lys His Ile Asn Ile Asp Gln Phe Val Arg
1 5 10
<210> 4132
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4132
Asn Leu Leu Asp Arg
1 5
<210> 4133
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4133
Asn Leu Leu His Val Thr Asp Thr Gly Val Gly Met Thr Arg
1 5 10
<210> 4134
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4134
Asn Leu Leu Leu Val Arg Pro Leu Gly Pro Gln Ala Ser Ile Arg
1 5 10 15
<210> 4135
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4135
Asn Leu Leu Ser Val Ala Tyr Lys
1 5
<210> 4136
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4136
Asn Leu Met His Leu Asp Leu Lys
1 5
<210> 4137
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4137
Asn Leu Met Tyr Val Asp Ile Pro Ile Val Asp His Gln Lys
1 5 10
<210> 4138
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4138
Asn Leu Asn Glu Lys Asp Tyr Glu Leu Leu Cys Leu Asp Gly Thr Arg
1 5 10 15
<210> 4139
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4139
Asn Leu Pro Glu Gln Val Phe Arg
1 5
<210> 4140
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4140
Asn Leu Pro Asn Gly Asp Phe Arg
1 5
<210> 4141
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4141
Asn Leu Gln Asn Asn Ala Glu Trp Val Tyr Gln Gly Ala Ile Arg
1 5 10 15
<210> 4142
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4142
Asn Leu Gln Pro Ala Ser Glu Tyr Thr Val Ser Leu Val Ala Ile Lys
1 5 10 15
<210> 4143
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4143
Asn Leu Gln Pro Ala Ser Glu Tyr Thr Val Ser Leu Val Ala Ile Lys
1 5 10 15
Gly Asn Gln Glu Ser Pro Lys
20
<210> 4144
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4144
Asn Leu Ser Leu Asn Ser Gln Ala Leu Lys
1 5 10
<210> 4145
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4145
Asn Leu Ser Met Gln Lys
1 5
<210> 4146
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4146
Asn Leu Ser Val Glu Asp Ala Ala Arg
1 5
<210> 4147
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4147
Asn Leu Thr Asp Phe Ala Glu Gln Tyr Ser Ile Gln Asp Trp Ala Lys
1 5 10 15
<210> 4148
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4148
Asn Leu Thr Leu Thr Arg
1 5
<210> 4149
<211> 35
<212> PRT
<213> Homo sapiens
<400> 4149
Asn Leu Val Ile Asn Cys Glu Val Phe Asp Pro Gln Glu His Glu Asn
1 5 10 15
Ile Asn Gly Val Pro Pro His Leu Gly His Pro Phe His Trp Gly Gly
20 25 30
His Glu Arg
35
<210> 4150
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4150
Asn Leu Val Leu His Ser Ala Arg Pro Gly Ala Pro Pro Pro Gln Pro
1 5 10 15
Leu Asp Leu Gln His Arg
20
<210> 4151
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4151
Asn Leu Trp Glu Lys
1 5
<210> 4152
<211> 35
<212> PRT
<213> Homo sapiens
<400> 4152
Asn Met Ala Thr Arg Pro Tyr Ser Ile His Ala His Gly Val Gln Thr
1 5 10 15
Glu Ser Ser Thr Val Thr Pro Thr Leu Pro Gly Glu Thr Leu Thr Tyr
20 25 30
Val Trp Lys
35
<210> 4153
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4153
Asn Met Glu Gln Phe Gln Val Ser Val Ser Val Ala Pro Asn Ala Lys
1 5 10 15
<210> 4154
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4154
Asn Met Glu Val Phe Phe Pro Lys
1 5
<210> 4155
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4155
Asn Met Glu Val Ser Val Ala Thr Thr Thr Lys
1 5 10
<210> 4156
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4156
Asn Met Asn Lys Glu Asp Glu Gly Glu Ile Thr Lys
1 5 10
<210> 4157
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4157
Asn Met Gln Asp Leu Val Glu Asp Phe Lys
1 5 10
<210> 4158
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4158
Asn Met Gln Asp Met Val Glu Asp Tyr Arg
1 5 10
<210> 4159
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4159
Asn Asn Ala Leu Asp Phe Val Thr Lys
1 5
<210> 4160
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4160
Asn Asn Ala Asn Gly Val Asp Leu Asn Arg
1 5 10
<210> 4161
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4161
Asn Asn Glu Glu Tyr Leu Ala Leu Ile Phe Glu Lys
1 5 10
<210> 4162
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4162
Asn Asn Glu Gly Thr Tyr Tyr Ser Pro Asn Tyr Asn Pro Gln Ser Arg
1 5 10 15
<210> 4163
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4163
Asn Asn Phe Glu Gly Glu Val Thr Lys
1 5
<210> 4164
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4164
Asn Asn Phe Val Ile Arg
1 5
<210> 4165
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4165
Asn Asn Lys Asp Ser His Ser Leu Thr Thr Asn Ile Met Glu Ile Leu
1 5 10 15
Arg
<210> 4166
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4166
Asn Asn Leu Glu Leu Ser Thr Pro Leu Lys
1 5 10
<210> 4167
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4167
Asn Asn Leu Glu Leu Ser Thr Pro Leu Lys Ile Glu Thr Ile Ser His
1 5 10 15
Glu Asp Leu Gln Arg
20
<210> 4168
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4168
Asn Asn Leu Leu Leu Lys
1 5
<210> 4169
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4169
Asn Asn Pro Ser Lys Pro Leu His Val Ile Lys
1 5 10
<210> 4170
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4170
Asn Asn Gln Ile Asp His Ile Asp Glu Lys
1 5 10
<210> 4171
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4171
Asn Asn Arg Trp Glu Asp Ile Leu Ser Asp Glu Val Asn Val Ala Arg
1 5 10 15
<210> 4172
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4172
Asn Asn Thr Val Gly Leu Ile Gln Leu Asn Arg Pro Lys
1 5 10
<210> 4173
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4173
Asn Asn Val Pro Cys Ser Pro Lys
1 5
<210> 4174
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4174
Asn Asn Val Val Ser Val Asn Lys
1 5
<210> 4175
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4175
Asn Pro Ala Asp Pro Gln Arg Ile Pro Ser Asn Pro Ser His Arg
1 5 10 15
<210> 4176
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4176
Asn Pro Ala Asn Pro Val Gln Arg
1 5
<210> 4177
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4177
Asn Pro Asp Ala Asp Glu Lys Pro Trp Cys Phe Ile Lys
1 5 10
<210> 4178
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4178
Asn Pro Asp Asn Asp Glu Arg Pro Trp Cys Tyr Val Val Lys
1 5 10
<210> 4179
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4179
Asn Pro Asp Asn Asp Ile Arg Pro Trp Cys Phe Val Leu Asn Arg
1 5 10 15
<210> 4180
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4180
Asn Pro Asp Asn Asp Pro Gln Gly Pro Trp Cys Tyr Thr Thr Asp Pro
1 5 10 15
Glu Lys
<210> 4181
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4181
Asn Pro Asp Asn Asp Pro Gln Gly Pro Trp Cys Tyr Thr Thr Asp Pro
1 5 10 15
Glu Lys Arg
<210> 4182
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4182
Asn Pro Asp Pro Trp Ala Lys
1 5
<210> 4183
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4183
Asn Pro Phe Val Phe Ala Pro Thr Leu Leu Thr Val Ala Val His Phe
1 5 10 15
Glu Glu Val Ala Lys
20
<210> 4184
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4184
Asn Pro Gly Asn Gln Ala Ala Tyr Glu His Phe Glu Thr Met Lys
1 5 10 15
<210> 4185
<211> 59
<212> PRT
<213> Homo sapiens
<400> 4185
Asn Pro Gly Ser Ser Gly Thr Gly Gly Thr Ala Thr Trp Lys Pro Gly
1 5 10 15
Ser Ser Gly Pro Gly Ser Thr Gly Ser Trp Asn Ser Gly Ser Ser Gly
20 25 30
Thr Gly Ser Thr Gly Asn Gln Asn Pro Gly Ser Pro Arg Pro Gly Ser
35 40 45
Thr Gly Thr Trp Asn Pro Gly Ser Ser Glu Arg
50 55
<210> 4186
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4186
Asn Pro His Pro Ser Ser Ala Phe Leu Asn Leu Ile Gly Phe Val Ser
1 5 10 15
Arg
<210> 4187
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4187
Asn Pro Leu Pro Ser Lys
1 5
<210> 4188
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4188
Asn Pro Leu Pro Ser Lys Glu Thr Ile Glu Gln Glu Lys
1 5 10
<210> 4189
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4189
Asn Pro Leu Val Trp Val His Ala Ser Pro Glu His Val Val Val Thr
1 5 10 15
Arg
<210> 4190
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4190
Asn Pro Asn Gly Tyr Ser Phe Ser Ile Pro Val Lys
1 5 10
<210> 4191
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4191
Asn Pro Asn Pro Ser Ala Pro Arg
1 5
<210> 4192
<211> 29
<212> PRT
<213> Homo sapiens
<400> 4192
Asn Pro Arg Glu Asp Tyr Leu Asp Val Tyr Val Phe Gly Val Gly Pro
1 5 10 15
Leu Val Asn Gln Val Asn Ile Asn Ala Leu Ala Ser Lys
20 25
<210> 4193
<211> 30
<212> PRT
<213> Homo sapiens
<400> 4193
Asn Pro Ser Asp Pro Met Pro Gln Ala Pro Ala Leu Trp Ile Glu Thr
1 5 10 15
Thr Ala Tyr Ala Leu Leu His Leu Leu Leu His Glu Gly Lys
20 25 30
<210> 4194
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4194
Asn Pro Ser Ser Ala Gly Ser Trp Asn Ser Gly Ser Ser Gly Pro Gly
1 5 10 15
Ser Thr Gly Asn Arg
20
<210> 4195
<211> 80
<212> PRT
<213> Homo sapiens
<400> 4195
Asn Pro Ser Ser Ala Gly Ser Trp Asn Ser Gly Ser Ser Gly Pro Gly
1 5 10 15
Ser Thr Gly Asn Arg Asn Pro Gly Ser Ser Gly Thr Gly Gly Thr Ala
20 25 30
Thr Trp Lys Pro Gly Ser Ser Gly Pro Gly Ser Thr Gly Ser Trp Asn
35 40 45
Ser Gly Ser Ser Gly Thr Gly Ser Thr Gly Asn Gln Asn Pro Gly Ser
50 55 60
Pro Arg Pro Gly Ser Thr Gly Thr Trp Asn Pro Gly Ser Ser Glu Arg
65 70 75 80
<210> 4196
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4196
Asn Gln Asp His Ala Lys
1 5
<210> 4197
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4197
Asn Gln Asp Val His Ser Ile Asn Leu Pro Phe Phe Glu Thr Leu Gln
1 5 10 15
Glu Tyr Phe Glu Arg
20
<210> 4198
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4198
Asn Gln Phe Asn Asp Tyr Thr Ser Lys
1 5
<210> 4199
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4199
Asn Gln Phe Asn Asp Tyr Thr Ser Lys Lys
1 5 10
<210> 4200
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4200
Asn Gln Phe Ser Leu Lys
1 5
<210> 4201
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4201
Asn Gln Gly Ile Glu Glu Ala Leu Lys
1 5
<210> 4202
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4202
Asn Gln Gly Ile Leu Glu Phe Tyr Gly Asp Asp Ile Ala Leu Leu Lys
1 5 10 15
<210> 4203
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4203
Asn Gln Gly Asn Thr Trp Leu Thr Ala Phe Val Leu Lys
1 5 10
<210> 4204
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4204
Asn Gln Gly Asn Thr Trp Leu Thr Ala Phe Val Leu Lys Thr Phe Ala
1 5 10 15
Gln Ala Arg
<210> 4205
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4205
Asn Gln Leu Thr Ser Asn Pro Glu Asn Thr Val Phe Asp Ala Lys
1 5 10 15
<210> 4206
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4206
Asn Gln Thr Ala Glu Lys Glu Glu Phe Glu His Gln Gln Lys
1 5 10
<210> 4207
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4207
Asn Gln Thr Ala Asn Leu Thr Asn Gln Gly Lys
1 5 10
<210> 4208
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4208
Asn Gln Val Val Ile Ala Ala Gly Arg
1 5
<210> 4209
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4209
Asn Arg Asp Val Val Leu Thr Thr Thr Phe Val Asp Asp Ile Lys
1 5 10 15
<210> 4210
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4210
Asn Arg Asn Asn Ala Leu Asp Phe Val Thr Lys
1 5 10
<210> 4211
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4211
Asn Arg Asn Val His Ser Gly Ser Thr Phe Phe Lys
1 5 10
<210> 4212
<211> 26
<212> PRT
<213> Homo sapiens
<400> 4212
Asn Arg Gln Glu Gly Leu Met Ile Ala Ser Ser Leu Leu Asn Glu Gly
1 5 10 15
Tyr Leu Gln Pro Ala Gly Asp Met Ser Lys
20 25
<210> 4213
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4213
Asn Arg Val Val Leu Ala Lys
1 5
<210> 4214
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4214
Asn Ser Glu Glu Phe Ala Ala Ala Met Ser Arg
1 5 10
<210> 4215
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4215
Asn Ser Gly Leu Thr Glu Glu Glu Ala Lys
1 5 10
<210> 4216
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4216
Asn Ser Ile Glu Ile Ile Ile Lys
1 5
<210> 4217
<211> 42
<212> PRT
<213> Homo sapiens
<400> 4217
Asn Ser Ile Thr Leu Thr Asn Leu Thr Pro Gly Thr Glu Tyr Val Val
1 5 10 15
Ser Ile Val Ala Leu Asn Gly Arg Glu Glu Ser Pro Leu Leu Ile Gly
20 25 30
Gln Gln Ser Thr Val Ser Asp Val Pro Arg
35 40
<210> 4218
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4218
Asn Ser Lys Ile Glu Ile Ser Glu Leu Asn Arg
1 5 10
<210> 4219
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4219
Asn Ser Leu Phe Glu Tyr Gln Lys
1 5
<210> 4220
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4220
Asn Ser Leu Phe Glu Tyr Gln Lys Asn Asn Lys
1 5 10
<210> 4221
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4221
Asn Ser Leu Phe Phe Ser Ala Gln Pro Phe Glu Ile Thr Ala Ser Thr
1 5 10 15
Asn Asn Glu Gly Asn Leu Lys
20
<210> 4222
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4222
Asn Ser Leu Lys Ile Glu Ile Pro Leu Pro Phe Gly Gly Lys
1 5 10
<210> 4223
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4223
Asn Ser Leu Trp His Thr Gly Asp Thr Ser Asp Gln Val Arg
1 5 10
<210> 4224
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4224
Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg
1 5 10
<210> 4225
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4225
Asn Ser Asn Pro Ala Leu Asn Asp Asn Leu Glu Lys
1 5 10
<210> 4226
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4226
Asn Ser Arg Pro Glu Ala Asn Glu Ala Leu Glu Arg
1 5 10
<210> 4227
<211> 28
<212> PRT
<213> Homo sapiens
<400> 4227
Asn Ser Val Asp Glu Leu Asn Asn Asn Val Glu Ala Val Ser Gln Thr
1 5 10 15
Ser Ser Ser Ser Phe Gln Tyr Met Tyr Leu Leu Lys
20 25
<210> 4228
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4228
Asn Ser Val Ile Lys Val Pro Met Met Asn Ser Lys
1 5 10
<210> 4229
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4229
Asn Thr Ala Glu Trp Leu Leu Ser His Thr Lys
1 5 10
<210> 4230
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4230
Asn Thr Ala Ser Leu Lys Tyr Glu Asn Tyr Glu Leu Thr Leu Lys
1 5 10 15
<210> 4231
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4231
Asn Thr Glu Ile Leu Thr Gly Ser Trp Ser Asp Gln Thr Tyr Pro Glu
1 5 10 15
Gly Thr Gln Ala Ile Tyr Lys
20
<210> 4232
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4232
Asn Thr Glu Ile Ser Phe Ile Leu Gly Gln Glu Phe Asp Glu Val Thr
1 5 10 15
Ala Asp Asp Arg Lys
20
<210> 4233
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4233
Asn Thr Glu Gln Glu Glu Gly Gly Glu Ala Val His Glu Val Glu Val
1 5 10 15
Val Ile Lys
<210> 4234
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4234
Asn Thr Phe Ala Glu Val Thr Gly Leu Ser Pro Gly Val Thr Tyr Tyr
1 5 10 15
Phe Lys
<210> 4235
<211> 26
<212> PRT
<213> Homo sapiens
<400> 4235
Asn Thr Phe Ala Glu Val Thr Gly Leu Ser Pro Gly Val Thr Tyr Tyr
1 5 10 15
Phe Lys Val Phe Ala Val Ser His Gly Arg
20 25
<210> 4236
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4236
Asn Thr Gly Arg Glu Glu Phe Leu Thr Ala Phe Leu Gln Asn Tyr Gln
1 5 10 15
Leu Ala Tyr Ser Lys
20
<210> 4237
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4237
Asn Thr Leu Glu Leu Ser Asn Gly Val Ile Val Lys
1 5 10
<210> 4238
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4238
Asn Thr Leu Ile Ile Tyr Leu Asp Lys
1 5
<210> 4239
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4239
Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg
1 5 10
<210> 4240
<211> 28
<212> PRT
<213> Homo sapiens
<400> 4240
Asn Thr Val Leu Val Leu Asn Thr Gln Ser Leu Val Phe Val Gln Thr
1 5 10 15
Asp Lys Pro Met Tyr Lys Pro Gly Gln Thr Val Arg
20 25
<210> 4241
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4241
Asn Thr Val Val Pro Thr Lys Lys
1 5
<210> 4242
<211> 26
<212> PRT
<213> Homo sapiens
<400> 4242
Asn Thr Trp Ser Ile Leu His Thr Gln Gly Ala Leu Val Gln Gly Gly
1 5 10 15
Tyr Gly His Ser Ser Val Tyr Asp His Arg
20 25
<210> 4243
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4243
Asn Thr Tyr Ser Ser Leu Glu Gly Lys
1 5
<210> 4244
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4244
Asn Val Ala Leu Val Ser Gly Asp Thr Glu Asn Ala Lys
1 5 10
<210> 4245
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4245
Asn Val Asp Glu Phe Lys
1 5
<210> 4246
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4246
Asn Val Asp Leu Leu Ser Asp Met Val Gln Glu His Asp Glu Pro Ile
1 5 10 15
Leu Lys
<210> 4247
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4247
Asn Val Phe Ile Ile Gly Ala Thr Asn Arg Pro Asp Ile Ile Asp Pro
1 5 10 15
Ala Ile Leu Arg Pro Gly Arg
20
<210> 4248
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4248
Asn Val His Gly Ile Asn Phe Val Ser Pro Val Arg
1 5 10
<210> 4249
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4249
Asn Val His Ser Ala Gly Ala Ala Gly Ser Arg
1 5 10
<210> 4250
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4250
Asn Val His Ser Gly Ser Thr Phe Phe Lys
1 5 10
<210> 4251
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4251
Asn Val Ile Gly Leu Gln Met Gly Thr Asn Arg
1 5 10
<210> 4252
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4252
Asn Val Leu Ile Asn Lys
1 5
<210> 4253
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4253
Asn Val Leu Val Thr Leu Tyr Glu Arg Asp Glu Asp Asn Asn Leu Leu
1 5 10 15
Thr Glu Lys
<210> 4254
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4254
Asn Val Asn Phe Gln Lys
1 5
<210> 4255
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4255
Asn Val Asn Ile Phe Lys
1 5
<210> 4256
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4256
Asn Val Asn Ile Gln Asn Phe His Ile Ser Trp Lys
1 5 10
<210> 4257
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4257
Asn Val Asn Val Gln Asn Phe His Ile Ser Trp Lys
1 5 10
<210> 4258
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4258
Asn Val Pro Phe Ser Glu Leu Asn Leu Lys
1 5 10
<210> 4259
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4259
Asn Val Gln Ala Leu Glu Ile Glu Leu Gln Ser Gln Leu Ala Leu Lys
1 5 10 15
<210> 4260
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4260
Asn Val Gln Asp Ala Ile Ala Asp Ala Glu Gln Arg Gly Glu His Ala
1 5 10 15
Leu Lys
<210> 4261
<211> 33
<212> PRT
<213> Homo sapiens
<400> 4261
Asn Val Gln Phe Asn Tyr Pro His Thr Ser Val Thr Asp Val Thr Gln
1 5 10 15
Asn Asn Phe His Asn Tyr Phe Gly Gly Ser Glu Ile Val Val Ala Gly
20 25 30
Lys
<210> 4262
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4262
Asn Val Arg Pro Asp Tyr Leu Lys
1 5
<210> 4263
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4263
Asn Val Thr Asn Asn Leu Lys
1 5
<210> 4264
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4264
Asn Val Thr Ser Met Ile Asn Leu Lys
1 5
<210> 4265
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4265
Asn Val Val Phe Val Ile Asp Ile Ser Gly Ser Met Arg
1 5 10
<210> 4266
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4266
Asn Val Val Phe Val Ile Asp Lys
1 5
<210> 4267
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4267
Asn Val Trp Val His Leu Asp Gly Pro Gly Val Thr Arg Pro Met Lys
1 5 10 15
<210> 4268
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4268
Asn Trp Glu Thr Glu Ile Thr Ala Gln Pro Asp Gly Gly Lys
1 5 10
<210> 4269
<211> 28
<212> PRT
<213> Homo sapiens
<400> 4269
Asn Trp Glu Thr Glu Ile Thr Ala Gln Pro Asp Gly Gly Lys Thr Glu
1 5 10 15
Asn Cys Ala Val Leu Ser Gly Ala Ala Asn Gly Lys
20 25
<210> 4270
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4270
Asn Trp Gly Leu Gly Gly His Ala Phe Cys Arg
1 5 10
<210> 4271
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4271
Asn Trp Gly Leu Ser Phe Tyr Ala Asp Lys Pro Glu Thr Thr Lys
1 5 10 15
<210> 4272
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4272
Asn Trp Gly Leu Ser Val Tyr Ala Asp Lys Pro Glu Thr Thr Lys
1 5 10 15
<210> 4273
<211> 29
<212> PRT
<213> Homo sapiens
<400> 4273
Asn Trp Gly Leu Ser Val Tyr Ala Asp Lys Pro Glu Thr Thr Lys Glu
1 5 10 15
Gln Leu Gly Glu Phe Tyr Glu Ala Leu Asp Cys Leu Arg
20 25
<210> 4274
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4274
Asn Trp Ile Gln Tyr Lys
1 5
<210> 4275
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4275
Asn Trp Met Asn Ser Leu Gly Val Asn Pro Arg
1 5 10
<210> 4276
<211> 25
<212> PRT
<213> Homo sapiens
<400> 4276
Asn Trp Arg Asp Pro Asp Gln Thr Asp Gly Leu Gly Leu Ser Tyr Leu
1 5 10 15
Ser Ser His Ile Ala Asn Val Glu Arg
20 25
<210> 4277
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4277
Asn Tyr Ala Glu Ala Lys Asp Val Phe Leu Gly Met Phe Leu Tyr Glu
1 5 10 15
Tyr Ala Arg
<210> 4278
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4278
Asn Tyr Cys Gly Leu Pro Gly Glu Tyr Trp Leu Gly Asn Asp Lys
1 5 10 15
<210> 4279
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4279
Asn Tyr Glu Glu Glu Ile Leu Arg
1 5
<210> 4280
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4280
Asn Tyr Asn Leu Val Glu Ser Leu Lys
1 5
<210> 4281
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4281
Asn Tyr Asn Leu Val Glu Ser Leu Lys Leu Met Gly Ile Arg
1 5 10
<210> 4282
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4282
Asn Tyr Pro Met His Val Phe Ala Tyr Arg
1 5 10
<210> 4283
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4283
Asn Tyr Gln Leu Tyr Lys
1 5
<210> 4284
<211> 25
<212> PRT
<213> Homo sapiens
<400> 4284
Asn Tyr Ser Pro Tyr Tyr Asn Thr Ile Asp Asp Leu Lys Asp Gln Ile
1 5 10 15
Val Asp Leu Thr Val Gly Asn Asn Lys
20 25
<210> 4285
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4285
Asn Tyr Val Asp Trp Ile Met Lys
1 5
<210> 4286
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4286
Pro Met Phe Ile Val Asn Thr Asn Val Pro Arg
1 5 10
<210> 4287
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4287
Pro Pro Tyr Thr Val Val Tyr Phe Pro Val Arg
1 5 10
<210> 4288
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4288
Pro Tyr Glu Ile Lys
1 5
<210> 4289
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4289
Pro Tyr Gln Tyr Pro Ala Leu Thr Pro Glu Gln Lys
1 5 10
<210> 4290
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4290
Gln Ala Ala Ala Ser Ala Thr Gln Thr Ile Ala Ala Ala Gln His Ala
1 5 10 15
Ala Ser Thr Pro Lys
20
<210> 4291
<211> 28
<212> PRT
<213> Homo sapiens
<400> 4291
Gln Ala Ala Gly Ser Gly His Leu Leu Ala Leu Gly Thr Pro Glu Asn
1 5 10 15
Pro Ser Trp Leu Ser Leu His Leu Gln Asp Gln Lys
20 25
<210> 4292
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4292
Gln Ala Glu Ala Val Leu Lys
1 5
<210> 4293
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4293
Gln Ala Glu Ile Ser Ala Ser Ala Pro Thr Ser Leu Arg
1 5 10
<210> 4294
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4294
Gln Ala Gly Leu Gly Asn His Leu Ser Gly Ser Glu Arg
1 5 10
<210> 4295
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4295
Gln Ala Ile Gln Ala Ser His Lys
1 5
<210> 4296
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4296
Gln Ala Ile Gln Ala Ser His Lys Lys
1 5
<210> 4297
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4297
Gln Ala Leu Ala Gln Ser Glu Pro Gly Gln Leu Ala Asp Ser Lys
1 5 10 15
<210> 4298
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4298
Gln Ala Leu Glu Glu Phe Gln Lys
1 5
<210> 4299
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4299
Gln Ala Leu Glu Phe Gln Leu Lys
1 5
<210> 4300
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4300
Gln Ala Leu Glu Leu Lys
1 5
<210> 4301
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4301
Gln Ala Met Gly Glu Leu Ser Glu Leu Ser Phe His Tyr Leu Ile Met
1 5 10 15
Ala Lys
<210> 4302
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4302
Gln Ala Val Asp Thr Ala Val Asp Gly Val Phe Ile Arg
1 5 10
<210> 4303
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4303
Gln Cys Ser Lys Glu Asp Gly Gly Gly Trp Trp Tyr Asn Arg
1 5 10
<210> 4304
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4304
Gln Asp Glu Glu Lys Pro Leu His Ala Leu Leu His Gly Arg
1 5 10
<210> 4305
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4305
Gln Asp Gly His Leu Trp Cys Ser Thr Thr Ser Asn Tyr Glu Gln Asp
1 5 10 15
Gln Lys
<210> 4306
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4306
Gln Asp Gly Ser Val Asp Phe Phe Arg
1 5
<210> 4307
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4307
Gln Asp Gly Ser Val Asp Phe Gly Arg
1 5
<210> 4308
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4308
Gln Asp Gly Ser Val Asp Phe Gly Arg Lys
1 5 10
<210> 4309
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4309
Gln Asp Asn Glu Ile Leu Ile Phe Trp Ser Lys
1 5 10
<210> 4310
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4310
Gln Asp Pro Pro Ser Val Val Val Thr Ser His Gln Ala Pro Gly Glu
1 5 10 15
Lys
<210> 4311
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4311
Gln Asp Arg Asp Leu Glu Glu Pro Ile Asn Phe Arg
1 5 10
<210> 4312
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4312
Gln Asp Ser Gln Leu Gln Lys
1 5
<210> 4313
<211> 24
<212> PRT
<213> Homo sapiens
<400> 4313
Gln Glu Ala Leu Glu Leu Met Asn Gln Asn Leu Asp Ile Tyr Glu Gln
1 5 10 15
Gln Val Met Thr Ala Ala Gln Lys
20
<210> 4314
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4314
Gln Glu Asp Asp Leu Ala Asn Ile Asn Gln Trp Val Lys
1 5 10
<210> 4315
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4315
Gln Glu Glu Leu Cys Leu Ala Arg
1 5
<210> 4316
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4316
Gln Glu Ile Phe Arg
1 5
<210> 4317
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4317
Gln Glu Ile Asn Ser His Val Glu Met Gln Thr Lys
1 5 10
<210> 4318
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4318
Gln Glu Leu Phe Arg
1 5
<210> 4319
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4319
Gln Glu Pro Gly Glu Asn Ser Glu Ile Leu Pro Thr Leu Lys
1 5 10
<210> 4320
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4320
Gln Glu Tyr Asp Glu Ser Gly Pro Ser Ile Val His Arg
1 5 10
<210> 4321
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4321
Gln Glu Tyr Glu Gln Leu Ile Ala Lys
1 5
<210> 4322
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4322
Gln Phe Phe His Leu Asn
1 5
<210> 4323
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4323
Gln Phe Gly Pro Tyr Cys Gly His Gly Phe Pro Gly Pro Leu Asn Ile
1 5 10 15
Glu Thr Lys
<210> 4324
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4324
Gln Phe His Gly Leu Leu Val Lys
1 5
<210> 4325
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4325
Gln Phe Pro Ile Leu Leu Asp Phe Lys
1 5
<210> 4326
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4326
Gln Phe Pro Ile Leu Leu Asp Phe Lys Thr Lys
1 5 10
<210> 4327
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4327
Gln Phe Ser Phe Pro Leu Ser Ser Glu Pro Phe Gln Gly Ser Tyr Lys
1 5 10 15
<210> 4328
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4328
Gln Phe Thr Ser Ser Thr Ser Tyr Asn Arg
1 5 10
<210> 4329
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4329
Gln Phe Thr Ser Ser Thr Ser Tyr Asn Arg Gly Asp Ser Thr Phe Glu
1 5 10 15
Ser Lys
<210> 4330
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4330
Gln Phe Val His Ile Lys
1 5
<210> 4331
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4331
Gln Gly Ala Leu Glu Leu Ile Lys
1 5
<210> 4332
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4332
Gln Gly Ala Leu Glu Leu Ile Lys Lys
1 5
<210> 4333
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4333
Gln Gly Asp Val Glu Cys Gln Arg
1 5
<210> 4334
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4334
Gln Gly Glu Leu Asn Lys
1 5
<210> 4335
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4335
Gln Gly Glu Thr Leu Asn Phe Leu Glu Ile Gly Tyr Ser Arg
1 5 10
<210> 4336
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4336
Gln Gly Phe Phe Pro Asp Ser Val Asn Lys
1 5 10
<210> 4337
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4337
Gln Gly Phe Gly Asn Val Ala Thr Asn Thr Asp Gly Lys
1 5 10
<210> 4338
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4338
Gln Gly His Phe Tyr Gly Glu Thr Ala Ala Val Tyr Val Ala Val Glu
1 5 10 15
Glu Arg
<210> 4339
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4339
Gln Gly His Asn Ser Val Phe Leu Ile Lys
1 5 10
<210> 4340
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4340
Gln Gly His Asn Ser Val Phe Leu Ile Lys Gly Asp Lys
1 5 10
<210> 4341
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4341
Gln Gly Ile Pro Phe Phe Ala Gln Val Leu Leu Val Asp Gly Lys
1 5 10 15
<210> 4342
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4342
Gln Gly Ile Pro Phe Phe Gly Gln Val Arg
1 5 10
<210> 4343
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4343
Gln Gly Leu Leu Pro Val Leu Glu Ser Phe Lys
1 5 10
<210> 4344
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4344
Gln Gly Pro Val Asn Leu Leu Ser Asp Pro Glu Gln Gly Val Glu Val
1 5 10 15
Thr Gly Gln Tyr Glu Arg
20
<210> 4345
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4345
Gln Gly Ser Phe Gln Gly Gly Phe Arg
1 5
<210> 4346
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4346
Gln Gly Tyr Phe Val Glu Ala Gln Pro Lys
1 5 10
<210> 4347
<211> 27
<212> PRT
<213> Homo sapiens
<400> 4347
Gln Gly Tyr Gln Leu Ile Glu Gly Asn Gln Val Leu His Ser Phe Thr
1 5 10 15
Ala Val Cys Gln Asp Asp Gly Thr Trp His Arg
20 25
<210> 4348
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4348
Gln His Asp Met Gly His Met Met Arg
1 5
<210> 4349
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4349
Gln His Phe Ser Gln Glu Ala Leu Leu Ser Val Ala His Arg
1 5 10
<210> 4350
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4350
Gln His Phe Thr Thr Leu Ile Lys
1 5
<210> 4351
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4351
Gln His Ile Glu Ala Ile Asp Val Arg
1 5
<210> 4352
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4352
Gln His Leu Phe Val Lys
1 5
<210> 4353
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4353
Gln His Leu Gly Asp Val Leu Asn Phe Leu Pro Leu
1 5 10
<210> 4354
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4354
Gln His Leu Pro Leu Ile Lys
1 5
<210> 4355
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4355
Gln His Pro Val Pro Pro Pro Ala Gln Asn Gln Asn Gln Val Arg
1 5 10 15
<210> 4356
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4356
Gln His Gln Leu Gly Val Trp Pro Leu Leu Pro Gly Ser Phe Lys
1 5 10 15
<210> 4357
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4357
Gln His Val Val Ser Val Glu Glu Ala Leu Leu Ala Thr Gly Gln Trp
1 5 10 15
Lys
<210> 4358
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4358
Gln His Val Val Tyr Gly Pro Trp Asn Leu Pro Gln Ser Ser Tyr Ser
1 5 10 15
His Leu Thr Arg
20
<210> 4359
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4359
Gln His Trp Val Val Phe Lys
1 5
<210> 4360
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4360
Gln Ile Ala Thr Leu His Ala Gln Val Ala Asp Met Lys Lys
1 5 10
<210> 4361
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4361
Gln Ile Asp Asp Ile Asp Val Arg
1 5
<210> 4362
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4362
Gln Ile Asp Asn Pro Asp Tyr Lys
1 5
<210> 4363
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4363
Gln Ile Asp Tyr Lys
1 5
<210> 4364
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4364
Gln Ile Gly Ser Val Tyr Arg
1 5
<210> 4365
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4365
Gln Ile Asn Asp Leu Lys
1 5
<210> 4366
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4366
Gln Ile Asn Asp Tyr Val Ala Lys
1 5
<210> 4367
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4367
Gln Ile Asn Asp Tyr Val Glu Lys
1 5
<210> 4368
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4368
Gln Ile Asn Asp Tyr Val Glu Lys Gly Thr Gln Gly Lys
1 5 10
<210> 4369
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4369
Gln Ile Asn Ser Tyr Val Lys
1 5
<210> 4370
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4370
Gln Ile Asn Tyr Lys
1 5
<210> 4371
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4371
Gln Ile Gln Asn Ile Lys
1 5
<210> 4372
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4372
Gln Ile Gln Val Lys
1 5
<210> 4373
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4373
Gln Ile Thr Val Asn Asp Leu Pro Val Gly Arg
1 5 10
<210> 4374
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4374
Gln Ile Val Leu Leu Phe Ala Val Phe Asp Glu Ser Lys
1 5 10
<210> 4375
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4375
Gln Ile Val Val Asp Lys
1 5
<210> 4376
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4376
Gln Lys Phe Gln Ser Val Phe Thr Val Thr Arg
1 5 10
<210> 4377
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4377
Gln Lys Leu His Glu Leu Gln Glu Lys
1 5
<210> 4378
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4378
Gln Lys Leu Gln Thr Val Leu Glu Ala Val His Asp Leu Leu Arg Pro
1 5 10 15
Arg
<210> 4379
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4379
Gln Lys Leu Thr Pro Leu Tyr Glu Leu Val Lys
1 5 10
<210> 4380
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4380
Gln Lys Pro Asp Gly Val Phe Gln Glu Asp Ala Pro Val Ile His Gln
1 5 10 15
Glu Met Ile Gly Gly Leu Arg
20
<210> 4381
<211> 29
<212> PRT
<213> Homo sapiens
<400> 4381
Gln Lys Thr Gly Leu Asp Ser Pro Thr Gly Ile Asp Phe Ser Asp Ile
1 5 10 15
Thr Ala Asn Ser Phe Thr Val His Trp Ile Ala Pro Arg
20 25
<210> 4382
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4382
Gln Lys Val Glu Pro Leu Arg
1 5
<210> 4383
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4383
Gln Lys Trp Glu Ala Glu Pro Val Tyr Val Gln Arg
1 5 10
<210> 4384
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4384
Gln Leu Ala Val Leu Asp Lys
1 5
<210> 4385
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4385
Gln Leu Glu Asp Ala Leu Lys
1 5
<210> 4386
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4386
Gln Leu Glu Glu Gln Leu Arg
1 5
<210> 4387
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4387
Gln Leu Glu Ile Tyr Lys
1 5
<210> 4388
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4388
Gln Leu Glu Leu Tyr Leu Pro Lys
1 5
<210> 4389
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4389
Gln Leu Glu Asn Leu Lys
1 5
<210> 4390
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4390
Gln Leu Glu Gln Val Ile Ala Lys
1 5
<210> 4391
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4391
Gln Leu Glu Trp Gly Leu Glu Arg
1 5
<210> 4392
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4392
Gln Leu Phe His Pro Glu Gln Leu Ile Thr Gly Lys
1 5 10
<210> 4393
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4393
Gln Leu Gly Ala Gly Ser Ile Glu Glu Cys Ala Ala Lys
1 5 10
<210> 4394
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4394
Gln Leu Gly Lys Leu Leu Leu Ser Thr Leu Thr Leu Leu Ser Lys
1 5 10 15
<210> 4395
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4395
Gln Leu Gly Leu Pro Gly Pro Pro Asp Val Pro Asp His Ala Ala Tyr
1 5 10 15
His Pro Phe Arg
20
<210> 4396
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4396
Gln Leu Gly Leu Pro Gly Pro Pro Asp Val Pro Asp His Ala Ala Tyr
1 5 10 15
His Pro Phe Arg Arg
20
<210> 4397
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4397
Gln Leu His Gly Leu Leu Gln Ala Arg
1 5
<210> 4398
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4398
Gln Leu Ile Glu Glu Lys
1 5
<210> 4399
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4399
Gln Leu Leu Ala Glu Arg
1 5
<210> 4400
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4400
Gln Leu Leu Asp Ala Lys
1 5
<210> 4401
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4401
Gln Leu Leu Glu Glu Lys
1 5
<210> 4402
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4402
Gln Leu Leu Gly Ser Ala His Ala Val Glu Val Phe His Arg
1 5 10
<210> 4403
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4403
Gln Leu Leu Ser Glu Arg
1 5
<210> 4404
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4404
Gln Leu Asn Glu Ile Asn Tyr Glu Asp His Lys
1 5 10
<210> 4405
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4405
Gln Leu Asn Glu Ile Asn Tyr Glu Asp His Lys Leu Lys
1 5 10
<210> 4406
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4406
Gln Leu Asn Ile Lys
1 5
<210> 4407
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4407
Gln Leu Asn Leu Lys
1 5
<210> 4408
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4408
Gln Leu Asn Gln Gln His Ser Gln Ile Lys
1 5 10
<210> 4409
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4409
Gln Leu Asn Tyr Lys
1 5
<210> 4410
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4410
Gln Leu Asn Tyr Lys His Tyr Asp Gly Ser Tyr Ser Thr Phe Gly Glu
1 5 10 15
Arg
<210> 4411
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4411
Gln Leu Pro Gly Gly Gln Asn Pro Val Ser Tyr Val Tyr Leu Glu Val
1 5 10 15
Val Ser Lys
<210> 4412
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4412
Gln Leu Pro Gly Gly Gln Asn Pro Val Ser Tyr Val Tyr Leu Glu Val
1 5 10 15
Val Ser Lys His Phe Ser Lys
20
<210> 4413
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4413
Gln Leu Pro Asn His Arg Val Leu Ile Met Lys
1 5 10
<210> 4414
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4414
Gln Leu Ser Phe Glu Glu Phe Ile Met Leu Met Ala Arg
1 5 10
<210> 4415
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4415
Gln Leu Thr Pro Tyr Ala Gln Arg
1 5
<210> 4416
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4416
Gln Leu Thr Ser Gly Pro Asn Gln Glu Gln Val Ser Pro Leu Thr Leu
1 5 10 15
Leu Lys
<210> 4417
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4417
Gln Leu Val Glu Ile Glu Lys
1 5
<210> 4418
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4418
Gln Leu Val Phe His Ile Gly His Gly Asp Leu Gly Ser Pro Ala Val
1 5 10 15
Leu Val Ser Arg
20
<210> 4419
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4419
Gln Leu Val His His Phe Glu Ile Asp Val Asp Ile Phe Glu Pro Gln
1 5 10 15
Gly Ile Ser Lys
20
<210> 4420
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4420
Gln Leu Val Ile Lys
1 5
<210> 4421
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4421
Gln Leu Val Leu Lys
1 5
<210> 4422
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4422
Gln Leu Val Leu Lys Ala Pro Asp Lys
1 5
<210> 4423
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4423
Gln Leu Tyr Gly Asp Thr Gly Val Leu Gly Arg
1 5 10
<210> 4424
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4424
Gln Leu Tyr His Lys
1 5
<210> 4425
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4425
Gln Leu Tyr Asn Val Glu Ala Thr Ser Tyr Ala Leu Leu Ala Leu Leu
1 5 10 15
Gln Leu Lys
<210> 4426
<211> 29
<212> PRT
<213> Homo sapiens
<400> 4426
Gln Leu Tyr Asn Val Glu Ala Thr Ser Tyr Ala Leu Leu Ala Leu Leu
1 5 10 15
Gln Leu Lys Asp Phe Asp Phe Val Pro Pro Val Val Arg
20 25
<210> 4427
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4427
Gln Met Ser Lys Tyr Pro Ser Gly Glu Arg
1 5 10
<210> 4428
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4428
Gln Asn Cys Glu Leu Phe Glu Gln Leu Gly Glu Tyr Lys
1 5 10
<210> 4429
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4429
Gln Asn Asp Phe Asn Ser Val Glu Glu Lys
1 5 10
<210> 4430
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4430
Gln Asn Asp Phe Asn Ser Val Glu Glu Lys Lys
1 5 10
<210> 4431
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4431
Gln Asn Ile Asp Gly His Gly Ser Asp Asp Ser Lys
1 5 10
<210> 4432
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4432
Gln Asn Leu Glu Pro Leu Phe Glu Gln Tyr Ile Asn Asn Leu Arg Arg
1 5 10 15
<210> 4433
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4433
Gln Pro Phe Val Gln Gly Leu Ala Leu Tyr Thr Pro Val Val Leu Pro
1 5 10 15
Arg
<210> 4434
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4434
Gln Pro Gln Phe Ile Ser Arg
1 5
<210> 4435
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4435
Gln Pro Ser Ser Ala Phe Ala Ala Phe Val Lys
1 5 10
<210> 4436
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4436
Gln Pro Ser Ser Ala Phe Ala Ala Phe Val Lys Arg
1 5 10
<210> 4437
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4437
Gln Pro Trp Gln Ala Lys
1 5
<210> 4438
<211> 31
<212> PRT
<213> Homo sapiens
<400> 4438
Gln Pro Tyr Ser Tyr Asp Phe Pro Glu Asp Val Ala Pro Ala Leu Gly
1 5 10 15
Thr Ser Phe Ser His Met Leu Gly Ala Thr Asn Pro Thr Gln Lys
20 25 30
<210> 4439
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4439
Gln Gln Asp His Phe Phe Gln Ala Ala Phe Leu Glu Glu Arg
1 5 10
<210> 4440
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4440
Gln Gln Glu Glu Leu Met Lys
1 5
<210> 4441
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4441
Gln Gln Glu Gln Gln Gln Gln Gln Val Ala Arg
1 5 10
<210> 4442
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4442
Gln Gln Leu Asn Leu Arg
1 5
<210> 4443
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4443
Gln Gln Leu Thr Gly His Ser Lys
1 5
<210> 4444
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4444
Gln Gln Asn Ala Gln Gly Gly Phe Ser Ser Thr Gln Asp Thr Val Val
1 5 10 15
Ala Leu His Ala Leu Ser Lys
20
<210> 4445
<211> 31
<212> PRT
<213> Homo sapiens
<400> 4445
Gln Gln Asn Ala Gln Gly Gly Phe Ser Ser Thr Gln Asp Thr Val Val
1 5 10 15
Ala Leu His Ala Leu Ser Lys Tyr Gly Ala Ala Thr Phe Thr Arg
20 25 30
<210> 4446
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4446
Gln Gln Asn Ala Gln Gly Gly Phe Ser Ser Thr Gln Asp Thr Val Val
1 5 10 15
Ala Leu His Ala Leu Ser Arg
20
<210> 4447
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4447
Gln Gln Thr Glu Trp Gln Ser Gly Gln Arg
1 5 10
<210> 4448
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4448
Gln Gln Thr His Met Leu Asp Val Met Gln Asp His Phe Ser Arg
1 5 10 15
<210> 4449
<211> 26
<212> PRT
<213> Homo sapiens
<400> 4449
Gln Arg Pro Pro Asp Leu Asp Thr Ser Ser Asn Ala Val Asp Leu Leu
1 5 10 15
Phe Phe Thr Asp Glu Ser Gly Asp Ser Arg
20 25
<210> 4450
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4450
Gln Arg Gln Glu Glu Leu Cys Leu Ala Arg
1 5 10
<210> 4451
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4451
Gln Arg Val Glu Ala Ser Ile Ser Lys
1 5
<210> 4452
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4452
Gln Ser Glu Asp Ser Thr Phe Tyr Leu Gly Glu Arg
1 5 10
<210> 4453
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4453
Gln Ser Glu Leu Ser Ala Lys
1 5
<210> 4454
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4454
Gln Ser Phe Asp Leu Ser Val Lys
1 5
<210> 4455
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4455
Gln Ser Gly Leu Tyr Phe Ile Lys Pro Leu Lys
1 5 10
<210> 4456
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4456
Gln Ser Ile Thr Asp Glu Leu Lys
1 5
<210> 4457
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4457
Gln Ser Lys Pro Gly Glu Asp Leu Lys
1 5
<210> 4458
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4458
Gln Ser Leu Glu Ala Ser Leu Ala Glu Thr Glu Gly Arg
1 5 10
<210> 4459
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4459
Gln Ser Leu Gly Glu Leu Ile Gly Thr Leu Asn Ala Ala Lys
1 5 10
<210> 4460
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4460
Gln Ser Leu Gly His Gly Gln His Gly Ser Gly Ser Gly Gln Ser Pro
1 5 10 15
Ser Pro Ser Arg
20
<210> 4461
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4461
Gln Ser Ser Glu Ile Thr Arg
1 5
<210> 4462
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4462
Gln Ser Ser Pro Asp Ser Val Lys
1 5
<210> 4463
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4463
Gln Ser Ser Ser Tyr Gly Pro His Gly Tyr Gly Ser Gly Arg
1 5 10
<210> 4464
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4464
Gln Ser Ser Ser Tyr Ser Phe Phe Lys
1 5
<210> 4465
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4465
Gln Ser Ser Ser Tyr Ser Phe Phe Lys Glu Glu Ile Ile Tyr Glu Cys
1 5 10 15
Asp Lys
<210> 4466
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4466
Gln Ser Thr Leu Asp Lys
1 5
<210> 4467
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4467
Gln Ser Thr Leu Asp Lys Glu Leu
1 5
<210> 4468
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4468
Gln Ser Thr Asn Ala Tyr Pro Asp Leu Arg
1 5 10
<210> 4469
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4469
Gln Ser Val Glu Ala Asp Ile Asn Gly Leu Arg Arg
1 5 10
<210> 4470
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4470
Gln Ser Val Glu His Phe Thr Lys
1 5
<210> 4471
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4471
Gln Thr Ala Cys Lys Pro Glu Ile Ala Tyr Ala Tyr Lys
1 5 10
<210> 4472
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4472
Gln Thr Ala Leu Val Glu Leu Val Lys
1 5
<210> 4473
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4473
Gln Thr Glu Ala Thr Met Thr Phe Lys
1 5
<210> 4474
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4474
Gln Thr His Gln Pro Pro Ala Pro Asn Ser Leu Ile Arg
1 5 10
<210> 4475
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4475
Gln Thr Ile Ile Val Val Leu Glu Asn Val Gln Arg
1 5 10
<210> 4476
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4476
Gln Thr Leu Glu Asn Glu Arg Gly Glu Leu Ala Asn Glu Val Lys
1 5 10 15
<210> 4477
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4477
Gln Thr Leu Ser Trp Thr Val Thr Pro Lys
1 5 10
<210> 4478
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4478
Gln Thr Gln Val Ser Val Leu Pro Glu Gly Gly Glu Thr Pro Leu Phe
1 5 10 15
Lys
<210> 4479
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4479
Gln Thr Val Glu Ala Met Lys
1 5
<210> 4480
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4480
Gln Thr Val Asn Leu Gln Leu Gln Pro Tyr Ser Leu Val Thr Thr Leu
1 5 10 15
Asn Ser Asp Leu Lys
20
<210> 4481
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4481
Gln Thr Val Ser Trp Ala Val Thr Pro Lys
1 5 10
<210> 4482
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4482
Gln Val Glu Gly Met Glu Asp Trp Lys
1 5
<210> 4483
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4483
Gln Val Glu Gly Met Glu Asp Trp Lys Gln Asp Ser Gln Leu Gln Lys
1 5 10 15
<210> 4484
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4484
Gln Val Phe Leu Tyr Pro Glu Lys Asp Glu Pro Thr Tyr Ile Leu Asn
1 5 10 15
Ile Lys
<210> 4485
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4485
Gln Val Lys Asp Asn Glu Asn Val Val Asn Glu Tyr Ser Ser Glu Leu
1 5 10 15
Glu Lys
<210> 4486
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4486
Gln Val Leu Leu Val Gly Ala Pro Thr Tyr Asp Asp Val Ser Lys
1 5 10 15
<210> 4487
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4487
Gln Val Asn Glu Pro His Ile Arg
1 5
<210> 4488
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4488
Gln Val Arg Pro Ile Val Gly Pro Phe His Ala Val Leu Lys
1 5 10
<210> 4489
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4489
Gln Val Ser Gly Pro Leu Thr Ser Lys
1 5
<210> 4490
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4490
Gln Val Thr Pro Leu Phe Ile His Phe Arg
1 5 10
<210> 4491
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4491
Gln Val Val Ala Gly Leu Asn Phe Arg
1 5
<210> 4492
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4492
Gln Val Val Glu Ser Ala Tyr Glu Val Ile Lys
1 5 10
<210> 4493
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4493
Gln Trp Ala Gly Leu Val Glu Lys
1 5
<210> 4494
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4494
Gln Trp Ile Asn Lys
1 5
<210> 4495
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4495
Gln Trp Leu Asn Lys
1 5
<210> 4496
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4496
Gln Tyr Ala Asp Thr Val Lys
1 5
<210> 4497
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4497
Gln Tyr Gly Phe Cys Lys
1 5
<210> 4498
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4498
Gln Tyr Leu Ile Met Gly Lys
1 5
<210> 4499
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4499
Gln Tyr Asn Val Gly Pro Ser Val Ser Lys
1 5 10
<210> 4500
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4500
Gln Tyr Asn Val Gly Pro Ser Val Ser Lys Tyr Pro Leu Arg
1 5 10
<210> 4501
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4501
Gln Tyr Arg Asn Gly Glu Ser Val Lys
1 5
<210> 4502
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4502
Gln Tyr Ser Leu Phe Lys
1 5
<210> 4503
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4503
Gln Tyr Thr Asp Ser Thr Phe Arg
1 5
<210> 4504
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4504
Gln Tyr Thr Asp Ser Thr Phe Arg Val Pro Val Glu Arg
1 5 10
<210> 4505
<211> 33
<212> PRT
<213> Homo sapiens
<400> 4505
Gln Tyr Trp Glu Tyr Gln Phe Gln His Gln Pro Ser Gln Glu Glu Cys
1 5 10 15
Glu Gly Ser Ser Leu Ser Ala Val Phe Glu His Phe Ala Met Met Gln
20 25 30
Arg
<210> 4506
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4506
Gln Tyr Tyr Glu Gly Ser Glu Ile Val Val Ala Gly Arg
1 5 10
<210> 4507
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4507
Arg Ala Pro Asp Leu Gln Asp Leu Pro Trp Gln Val Lys
1 5 10
<210> 4508
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4508
Arg Ala Pro Ser Thr Trp Leu Thr Ala Tyr Val Val Lys
1 5 10
<210> 4509
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4509
Arg Ala Pro Trp Cys His Thr Thr Asn Ser Gln Val Arg
1 5 10
<210> 4510
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4510
Arg Ala Pro Tyr Pro Asn Tyr Asp Arg
1 5
<210> 4511
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4511
Arg Ala Gln Leu Gly Asp Leu Pro Trp Gln Val Ala Ile Lys
1 5 10
<210> 4512
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4512
Arg Ala Thr Glu Glu Ile Ser Lys
1 5
<210> 4513
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4513
Arg Ala Thr Thr Val Thr Gly Thr Pro Cys Gln Asp Trp Ala Ala Gln
1 5 10 15
Glu Pro His Arg
20
<210> 4514
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4514
Arg Asp Phe Thr Phe Asp Leu Tyr Arg
1 5
<210> 4515
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4515
Arg Asp Gly Tyr Leu Phe Gln Leu Leu Arg
1 5 10
<210> 4516
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4516
Arg Asp Leu Glu Ile Glu Val Val Leu Phe His Pro Asn Tyr Asn Ile
1 5 10 15
Asn Gly Lys
<210> 4517
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4517
Arg Asp Pro Ser Pro Val Ser Gly Pro Val His Leu Phe Arg
1 5 10
<210> 4518
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4518
Arg Asp Ser Trp Leu Asp Lys
1 5
<210> 4519
<211> 39
<212> PRT
<213> Homo sapiens
<400> 4519
Arg Asp Thr Ala Asn Leu Phe Pro Gln Thr Ser Leu Thr Leu His Met
1 5 10 15
Trp Pro Asp Thr Glu Gly Thr Phe Asn Val Glu Cys Leu Thr Thr Asp
20 25 30
His Tyr Thr Gly Gly Met Lys
35
<210> 4520
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4520
Arg Asp Thr Met Val Glu Asp Leu Val Val Leu Val Arg
1 5 10
<210> 4521
<211> 26
<212> PRT
<213> Homo sapiens
<400> 4521
Arg Glu Asp Phe Asp Val Glu Ala Ala Asp Ser Ala Gly Asn Cys Leu
1 5 10 15
Asp Ser Leu Val Phe Val Ala Gly Asp Arg
20 25
<210> 4522
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4522
Arg Glu Asp Gly Ser Val Asn Phe Phe Arg
1 5 10
<210> 4523
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4523
Arg Glu Glu Ala Pro Ser Leu Arg Pro Ala Pro Pro Pro Ile Ser Gly
1 5 10 15
Gly Gly Tyr Arg
20
<210> 4524
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4524
Arg Glu Glu Phe Trp Leu Gly Leu Asp Asn Leu Asn Lys
1 5 10
<210> 4525
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4525
Arg Glu Leu Asp Glu Ser Leu Gln Val Ala Glu Arg
1 5 10
<210> 4526
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4526
Arg Glu Leu Leu Met Lys
1 5
<210> 4527
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4527
Arg Glu Pro Ala Val Gly Glu Pro Ala Glu Val Thr Thr Thr Val Leu
1 5 10 15
Val Arg
<210> 4528
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4528
Arg Glu Gln Pro Pro Ser Leu Thr Arg
1 5
<210> 4529
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4529
Arg Phe Asp Glu Ile Leu Glu Ala Ser Asp Gly Ile Met Val Ala Arg
1 5 10 15
<210> 4530
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4530
Arg Phe Glu Gln Leu Glu Leu Arg Pro Val Leu Tyr Asn Tyr Leu Asp
1 5 10 15
Lys
<210> 4531
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4531
Arg Phe Asn Ala Leu Gln Tyr Leu Arg
1 5
<210> 4532
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4532
Arg Phe Thr Val Glu Thr Pro Asp Lys
1 5
<210> 4533
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4533
Arg Gly Asp Ala Cys Glu Gly Asp Ser Gly Gly Pro Phe Val Met Lys
1 5 10 15
<210> 4534
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4534
Arg Gly Asp Leu Pro Phe Val Val Pro Arg
1 5 10
<210> 4535
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4535
Arg Gly Asp Ser Pro Trp Gln Val Val Leu Leu Asp Ser Lys
1 5 10
<210> 4536
<211> 26
<212> PRT
<213> Homo sapiens
<400> 4536
Arg Gly Glu Asn Leu Phe Ala Ile Thr Asp Glu Gly Met Asp Val Pro
1 5 10 15
Leu Ala Met Glu Glu Trp His His Glu Arg
20 25
<210> 4537
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4537
Arg Gly Glu Thr Glu Ser Glu Glu Phe Glu Lys
1 5 10
<210> 4538
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4538
Arg Gly His Leu Phe Leu Gln Thr Asp Gln Pro Ile Tyr Asn Pro Gly
1 5 10 15
Gln Arg
<210> 4539
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4539
Arg Gly Ile Ile Ser Ala Leu Leu Val Pro Pro Glu Thr Glu Glu Ala
1 5 10 15
Lys
<210> 4540
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4540
Arg Gly Ile Leu Thr Leu Lys
1 5
<210> 4541
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4541
Arg Gly Leu Glu Ser Asn Val Asn Val Glu Leu Leu Asn Ala Leu His
1 5 10 15
Ser His Met Ile Asn Lys
20
<210> 4542
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4542
Arg Gly Leu Gln Val Ala Leu Glu Glu Phe His Lys
1 5 10
<210> 4543
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4543
Arg Gly Pro Gly Gly Ala Trp Ala Ala Glu Val Ile Ser Asp Ala Arg
1 5 10 15
<210> 4544
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4544
Arg Gly Pro Gly Gly Ala Trp Ala Ala Glu Val Ile Ser Asn Ala Arg
1 5 10 15
<210> 4545
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4545
Arg Gly Ser Phe Asp Tyr Lys
1 5
<210> 4546
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4546
Arg His Leu Thr Gly Glu Phe Glu Lys
1 5
<210> 4547
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4547
Arg His Leu Val Pro Gly Ala Pro Phe Leu Leu Gln Ala Leu Val Arg
1 5 10 15
<210> 4548
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4548
Arg His Pro Asp Leu Ser Ile Pro Glu Leu Leu Arg
1 5 10
<210> 4549
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4549
Arg His Pro Asp Tyr Ser Val Val Leu Leu Leu Arg
1 5 10
<210> 4550
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4550
Arg His Pro Tyr Phe Tyr Ala Pro Glu Leu Leu Phe Phe Ala Lys
1 5 10 15
<210> 4551
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4551
Arg Ile Asp Ile Thr Leu Ser Ser Val Lys
1 5 10
<210> 4552
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4552
Arg Ile Glu Asp Ile His Leu Leu Val Glu Arg
1 5 10
<210> 4553
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4553
Arg Ile Glu Ser Leu Ile Asp Arg
1 5
<210> 4554
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4554
Arg Ile Phe Ser Pro Phe Ala Asp Leu Ser Glu Leu Ser Ala Thr Gly
1 5 10 15
Arg
<210> 4555
<211> 45
<212> PRT
<213> Homo sapiens
<400> 4555
Arg Ile His Glu Asp Ser Asp Ser Ala Leu Gln Leu Gln Asp Phe Tyr
1 5 10 15
Gln Glu Val Ala Asn Pro Leu Leu Thr Ala Val Thr Phe Glu Tyr Pro
20 25 30
Ser Asn Ala Val Glu Glu Val Thr Gln Asn Asn Phe Arg
35 40 45
<210> 4556
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4556
Arg Ile Leu Pro Leu Thr Val Cys Lys
1 5
<210> 4557
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4557
Arg Ile Leu Tyr Lys
1 5
<210> 4558
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4558
Arg Ile Pro Ile Glu Asp Gly Ser Gly Glu Val Val Leu Ser Arg
1 5 10 15
<210> 4559
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4559
Arg Ile Pro Leu Tyr Tyr Pro Asn Ala Gly Leu Thr Arg
1 5 10
<210> 4560
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4560
Arg Ile Gln Leu Val Glu Glu Glu Leu Asp Arg
1 5 10
<210> 4561
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4561
Arg Ile Val Ile Glu Tyr Val Asp Arg
1 5
<210> 4562
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4562
Arg Ile Tyr Gly Gly Phe Lys
1 5
<210> 4563
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4563
Arg Lys Pro Val Glu Gly Tyr Asp Ile Ser Phe Leu Ile Thr Asn Phe
1 5 10 15
His Thr Glu Gln Met Tyr Lys
20
<210> 4564
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4564
Arg Leu Asp Gly Ser Val Asp Phe Lys
1 5
<210> 4565
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4565
Arg Leu Glu Val Asp Ile Asp Ile Lys
1 5
<210> 4566
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4566
Arg Leu Phe Gln Pro Leu Thr His Leu Lys
1 5 10
<210> 4567
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4567
Arg Leu Gly Met Phe Asn Ile Gln His Cys Lys
1 5 10
<210> 4568
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4568
Arg Leu Gly Val Tyr Glu Leu Leu Leu Lys
1 5 10
<210> 4569
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4569
Arg Leu Ile Asp Gln Tyr Gly Thr His Tyr Leu Gln Ser Gly Ser Leu
1 5 10 15
Gly Gly Glu Tyr Arg
20
<210> 4570
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4570
Arg Leu Met Gln Cys Leu Pro Asn Pro Glu Asp Val Lys
1 5 10
<210> 4571
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4571
Arg Leu Met Val Glu Leu His Asn Leu Tyr Arg
1 5 10
<210> 4572
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4572
Arg Leu Met Val Lys
1 5
<210> 4573
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4573
Arg Leu Pro Asp Thr Gly Ser Lys
1 5
<210> 4574
<211> 24
<212> PRT
<213> Homo sapiens
<400> 4574
Arg Leu Pro Gly Asp Ile Gln Val Val Pro Ile Gly Val Gly Pro Asn
1 5 10 15
Ala Asn Val Gln Glu Leu Glu Arg
20
<210> 4575
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4575
Arg Leu Pro Ile Gly Ser Tyr Phe
1 5
<210> 4576
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4576
Arg Leu Pro Leu Glu Tyr Ser Tyr Gly Glu Tyr Arg
1 5 10
<210> 4577
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4577
Arg Leu Gln Ala Ala Gly Asn Ala Val Lys
1 5 10
<210> 4578
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4578
Arg Leu Gln Glu Ala Leu Glu Arg
1 5
<210> 4579
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4579
Arg Leu Ser Glu Asp Tyr Gly Val Leu Lys
1 5 10
<210> 4580
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4580
Arg Leu Ser Asn Glu Asn His Gly Ile Ala Gln Arg
1 5 10
<210> 4581
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4581
Arg Leu Thr Val Gly Ala Ala Gln Val Pro Ala Gln Leu Leu Val Gly
1 5 10 15
Ala Leu Arg
<210> 4582
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4582
Arg Leu Val Asn Ile Ala Val Asp Glu Arg
1 5 10
<210> 4583
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4583
Arg Leu Trp Trp Leu Asp Leu Lys
1 5
<210> 4584
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4584
Arg Leu Tyr Asp Val Leu Arg
1 5
<210> 4585
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4585
Arg Leu Tyr Gly Ser Glu Ala Phe Ala Thr Asp Phe Gln Asp Ser Ala
1 5 10 15
Ala Ala Lys
<210> 4586
<211> 27
<212> PRT
<213> Homo sapiens
<400> 4586
Arg Met Pro Ile Thr Tyr Asp Asn Gly Phe Leu Phe Ile His Thr Asp
1 5 10 15
Lys Pro Val Tyr Thr Pro Asp Gln Ser Val Lys
20 25
<210> 4587
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4587
Arg Met Val Val Pro Ala Ala Leu Lys
1 5
<210> 4588
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4588
Arg Asn Asp Tyr Leu Asp Ile Tyr Ala Ile Gly Val Gly Lys
1 5 10
<210> 4589
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4589
Arg Asn Phe Gly Tyr Thr Leu Arg
1 5
<210> 4590
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4590
Arg Asn His Met Gln Tyr Glu Ile Val Ile Lys
1 5 10
<210> 4591
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4591
Arg Asn Pro Phe Val Phe Ala Pro Thr Leu Leu Thr Val Ala Val His
1 5 10 15
Phe Glu Glu Val Ala Lys
20
<210> 4592
<211> 29
<212> PRT
<213> Homo sapiens
<400> 4592
Arg Asn Pro Pro Met Gly Gly Asn Val Val Ile Phe Asp Thr Val Ile
1 5 10 15
Thr Asn Gln Glu Glu Pro Tyr Gln Asn His Ser Gly Arg
20 25
<210> 4593
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4593
Arg Asn Ser Val Arg
1 5
<210> 4594
<211> 24
<212> PRT
<213> Homo sapiens
<400> 4594
Arg Asn Thr Glu Ile Leu Thr Gly Ser Trp Ser Asp Gln Thr Tyr Pro
1 5 10 15
Glu Gly Thr Gln Ala Ile Tyr Lys
20
<210> 4595
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4595
Arg Pro Ala Leu Asn Tyr Pro Val Tyr Gly Glu Thr Thr Gln Val Arg
1 5 10 15
<210> 4596
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4596
Arg Pro Ala Ser Pro Ile Ser Thr Ile Gln Pro Lys
1 5 10
<210> 4597
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4597
Arg Pro Cys Phe Glu Ser Leu Lys
1 5
<210> 4598
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4598
Arg Pro Cys Phe Ser Ala Leu Glu Val Asp Glu Thr Tyr Val Pro Lys
1 5 10 15
<210> 4599
<211> 27
<212> PRT
<213> Homo sapiens
<400> 4599
Arg Pro Cys Gly His Pro Gly Asp Thr Pro Phe Gly Thr Phe Thr Leu
1 5 10 15
Thr Gly Gly Asn Val Phe Glu Tyr Gly Val Lys
20 25
<210> 4600
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4600
Arg Pro Asp Ser Leu Gln His Val Leu Leu Pro Val Leu Asp Arg
1 5 10 15
<210> 4601
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4601
Arg Pro Phe Leu Ser Ile Ile Ser Ala Arg
1 5 10
<210> 4602
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4602
Arg Pro Gly Glu Ile Val Lys
1 5
<210> 4603
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4603
Arg Pro Gly Gly Glu Pro Ser Pro Glu Gly Thr Thr Gly Gln Ser Tyr
1 5 10 15
Asn Gln Tyr Ser Gln Arg
20
<210> 4604
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4604
Arg Pro Gly Val Tyr Thr Gln Val Thr Lys
1 5 10
<210> 4605
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4605
Arg Pro His Phe Phe Phe Pro Lys
1 5
<210> 4606
<211> 34
<212> PRT
<213> Homo sapiens
<400> 4606
Arg Pro Leu Glu Gln Gln Gln Pro His His Ile Pro Thr Ser Ala Pro
1 5 10 15
Val Tyr Gln Gln Pro Gln Gln Gln Pro Val Ala Gln Ser Tyr Gly Gly
20 25 30
Tyr Lys
<210> 4607
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4607
Arg Pro Pro Gly Phe Ser Pro Phe Arg
1 5
<210> 4608
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4608
Arg Pro Pro Leu Cys Tyr His Asn Gly Val Gln Tyr Arg
1 5 10
<210> 4609
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4609
Arg Pro Gln Asp Ala Lys Asn Thr Met Ile Leu Glu Ile Cys Thr Arg
1 5 10 15
<210> 4610
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4610
Arg Pro Gln Tyr Ile Lys
1 5
<210> 4611
<211> 28
<212> PRT
<213> Homo sapiens
<400> 4611
Arg Pro Ser Cys Asp Ile Asp Lys Pro Pro Pro Asn Ile Glu Leu Thr
1 5 10 15
Gly Asn Gly Tyr Asn Glu Leu Thr Gly Gln Phe Arg
20 25
<210> 4612
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4612
Arg Pro Ser Glu Ile Val Ile Gly Gln Cys Lys
1 5 10
<210> 4613
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4613
Arg Pro Ser Ser Gln Gly Trp Ala Ser Pro Gln Val Ala Gly Arg
1 5 10 15
<210> 4614
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4614
Arg Pro Thr Leu Thr Thr Phe Phe Gly Arg
1 5 10
<210> 4615
<211> 26
<212> PRT
<213> Homo sapiens
<400> 4615
Arg Pro Val Pro Ile Ser Tyr His Gln Leu Glu Ala Phe Tyr Ser Ile
1 5 10 15
Phe Thr Thr Glu Gln Gln Asp His Val Lys
20 25
<210> 4616
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4616
Arg Pro Trp Asn Val Ala Ser Leu Ile Tyr Glu Thr Lys
1 5 10
<210> 4617
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4617
Arg Pro Tyr Phe Pro Val Ala Val Gly Lys
1 5 10
<210> 4618
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4618
Arg Pro Tyr Leu Lys
1 5
<210> 4619
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4619
Arg Gln Ala Val Asp Thr Ala Val Asp Gly Val Phe Ile Arg
1 5 10
<210> 4620
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4620
Arg Gln Asp Gly Ser Val Asp Phe Phe Arg
1 5 10
<210> 4621
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4621
Arg Gln Asp Asn Glu Ile Leu Ile Phe Trp Ser Lys
1 5 10
<210> 4622
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4622
Arg Gln Gly Ala Leu Glu Leu Ile Lys
1 5
<210> 4623
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4623
Arg Gln Leu Glu Glu Ala Glu Glu Glu Ala Gln Arg
1 5 10
<210> 4624
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4624
Arg Gln Leu Thr Pro Tyr Ala Gln Arg
1 5
<210> 4625
<211> 26
<212> PRT
<213> Homo sapiens
<400> 4625
Arg Gln Asn Gly Ala Ala Leu Thr Ser Ala Ser Ile Leu Ala Gln Gln
1 5 10 15
Val Trp Gly Thr Leu Val Leu Leu Gln Arg
20 25
<210> 4626
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4626
Arg Gln Gln Pro Gly Pro Ser Glu His Ile Glu Arg
1 5 10
<210> 4627
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4627
Arg Gln Ser Glu Asp Ser Thr Phe Tyr Leu Gly Glu Arg
1 5 10
<210> 4628
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4628
Arg Ser Glu Asn Ile Asn His Asn Ser Ala Phe Lys
1 5 10
<210> 4629
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4629
Arg Ser Phe Leu Leu Asp Leu Leu Asn Ala Thr Gly Lys
1 5 10
<210> 4630
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4630
Arg Thr Asp Glu Ala Ala Phe Gln Lys
1 5
<210> 4631
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4631
Arg Thr Phe Val Leu Ser Ala Leu Gln Pro Ser Pro Thr His Ser Ser
1 5 10 15
Ser Asn Thr Gln Arg
20
<210> 4632
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4632
Arg Thr His Leu Pro Glu Val Phe Leu Ser Lys
1 5 10
<210> 4633
<211> 36
<212> PRT
<213> Homo sapiens
<400> 4633
Arg Thr Leu Thr Ser Val Ser Val Phe Val Asp His His Leu Ala Pro
1 5 10 15
Ser Phe Tyr Phe Val Ala Phe Tyr Tyr His Gly Asp His Pro Val Ala
20 25 30
Asn Ser Leu Arg
35
<210> 4634
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4634
Arg Thr Asn Ala Glu Asn Glu Phe Val Thr Ile Lys
1 5 10
<210> 4635
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4635
Arg Thr Pro His Glu Lys
1 5
<210> 4636
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4636
Arg Thr Pro Ile Thr Val Val Lys
1 5
<210> 4637
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4637
Arg Thr Thr Val Met Val Lys
1 5
<210> 4638
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4638
Arg Val Ala Glu Gly Thr Gln Val Leu Glu Leu Pro Phe Lys
1 5 10
<210> 4639
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4639
Arg Val Ala Gly Ser Val Thr Glu Leu Ile Gln Ala Ala Glu Ala Met
1 5 10 15
Lys
<210> 4640
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4640
Arg Val Asp Ala Asp Ala Asp Pro Arg
1 5
<210> 4641
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4641
Arg Val Asp Gly Ser Val Asp Phe Tyr Arg
1 5 10
<210> 4642
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4642
Arg Val Asp Thr Val Asp Pro Pro Tyr Pro Arg
1 5 10
<210> 4643
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4643
Arg Val Glu Asp Leu His Val Gly Ala Thr Val Ala Pro Ser Ser Arg
1 5 10 15
<210> 4644
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4644
Arg Val Glu Pro Tyr Gly Glu Asn Phe Asn Lys
1 5 10
<210> 4645
<211> 28
<212> PRT
<213> Homo sapiens
<400> 4645
Arg Val His Ala Asn Pro Leu Leu Ile Asp Val Val Thr Tyr Leu Val
1 5 10 15
Ala Leu Ile Pro Glu Pro Ser Ala Gln Gln Leu Arg
20 25
<210> 4646
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4646
Arg Val Ile Ile Ser Ala Pro Ser Ala Asp Ala Pro Met Phe Val Met
1 5 10 15
Gly Val Asn His Glu Lys
20
<210> 4647
<211> 31
<212> PRT
<213> Homo sapiens
<400> 4647
Arg Val Ile Asn Leu Pro Leu Asp Ser Met Ala Ala Pro Trp Glu Thr
1 5 10 15
Gly Asp Thr Phe Pro Asp Val Val Ala Ile Ala Pro Asp Val Arg
20 25 30
<210> 4648
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4648
Arg Val Leu Phe Ala Lys
1 5
<210> 4649
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4649
Arg Val Pro Phe Ser Leu Leu Arg
1 5
<210> 4650
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4650
Arg Val Gln Leu Tyr Asp Leu Gly Leu Gln Ile His Lys
1 5 10
<210> 4651
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4651
Arg Val Ser Leu Ala Thr Val Asp Lys
1 5
<210> 4652
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4652
Arg Val Ser Tyr Val Gly Leu Val Thr Val Arg
1 5 10
<210> 4653
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4653
Arg Val Trp Glu Leu Ser Lys
1 5
<210> 4654
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4654
Arg Val Trp Asn Tyr Phe Gln Arg
1 5
<210> 4655
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4655
Arg Trp Glu Leu Cys Asp Ile Pro Arg
1 5
<210> 4656
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4656
Arg Tyr Asp Leu Ser Ala Leu Val Arg
1 5
<210> 4657
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4657
Arg Tyr Ile Glu Thr Asp Pro Ala Asn Arg
1 5 10
<210> 4658
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4658
Arg Tyr Ser Ala Trp Ala Glu Ser Val Thr Asn Leu Pro Gln Val Ile
1 5 10 15
Lys
<210> 4659
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4659
Arg Tyr Thr Ile Ala Ala Leu Leu Ser Pro Tyr Ser Tyr Ser Thr Thr
1 5 10 15
Ala Val Val Thr Asn Pro Lys
20
<210> 4660
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4660
Arg Tyr Thr Leu Asn Ile Leu Glu Glu Ile Gly Gly Gly Gln Lys
1 5 10 15
<210> 4661
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4661
Ser Ala Ala Thr Leu Gln Gln Glu Lys
1 5
<210> 4662
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4662
Ser Ala Asp Phe Thr Asn Phe Asp Pro Arg
1 5 10
<210> 4663
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4663
Ser Ala Glu Ala Pro Gln Ser Pro Ala Val Tyr Ala Arg
1 5 10
<210> 4664
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4664
Ser Ala Gly Leu Val Lys
1 5
<210> 4665
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4665
Ser Ala Gly Leu Val Lys Ala Thr Gly Arg
1 5 10
<210> 4666
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4666
Ser Ala Gly Ser Val Glu Ser Pro Ser Val Ser Ser Thr His Arg
1 5 10 15
<210> 4667
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4667
Ser Ala Lys Pro Gly Gln Glu Glu Asp Gly Pro Leu Lys Gly Lys
1 5 10 15
<210> 4668
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4668
Ser Ala Lys Pro Thr Lys Pro Ala Ala Ser Asp Leu Pro Val Pro Ala
1 5 10 15
Glu Gly Val Arg
20
<210> 4669
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4669
Ser Ala Leu Phe Ala Gln Ile Asn Gln Gly Glu Ser Ile Thr His Ala
1 5 10 15
Leu Lys
<210> 4670
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4670
Ser Ala Leu Thr Trp His Gln Ala Arg
1 5
<210> 4671
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4671
Ser Ala Leu Val Leu Gln Tyr Leu Arg
1 5
<210> 4672
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4672
Ser Ala Ser Asp Leu Thr Trp Asp Asn Leu Lys
1 5 10
<210> 4673
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4673
Ser Ala Ser Leu His Leu Pro Lys
1 5
<210> 4674
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4674
Ser Ala Ser Asn Met Ala Ile Val Asp Val Lys
1 5 10
<210> 4675
<211> 24
<212> PRT
<213> Homo sapiens
<400> 4675
Ser Ala Ser Asn Met Ala Ile Val Asp Val Lys Met Val Ser Gly Phe
1 5 10 15
Ile Pro Leu Lys Pro Thr Val Lys
20
<210> 4676
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4676
Ser Ala Val Asp Ala Gly Phe Leu Gln Lys
1 5 10
<210> 4677
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4677
Ser Ala Val Thr Ala Leu Trp Gly Lys
1 5
<210> 4678
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4678
Ser Cys Ala Val Ala Glu Tyr Gly Val Tyr Val Lys
1 5 10
<210> 4679
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4679
Ser Cys Asp Ile Pro Val Phe Met Asn Ala Arg
1 5 10
<210> 4680
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4680
Ser Cys Glu Tyr Lys
1 5
<210> 4681
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4681
Ser Cys Gly Leu His Gln Leu Leu Arg
1 5
<210> 4682
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4682
Ser Cys His Thr Ala Val Gly Arg
1 5
<210> 4683
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4683
Ser Asp Asp Lys Val Thr Leu Glu Glu Arg
1 5 10
<210> 4684
<211> 41
<212> PRT
<213> Homo sapiens
<400> 4684
Ser Asp Glu His Val Val Ser Gly Asn Leu Val Thr Pro Leu Pro Val
1 5 10 15
Ile Leu Gly His Glu Ala Ala Gly Ile Val Glu Ser Val Gly Glu Gly
20 25 30
Val Thr Thr Val Lys Pro Gly Asp Lys
35 40
<210> 4685
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4685
Ser Asp Glu Asn Glu Gln His Leu Gly Val Lys
1 5 10
<210> 4686
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4686
Ser Asp Phe Ser Asn Glu Glu Arg
1 5
<210> 4687
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4687
Ser Asp Ile Ala Pro Val Ala Arg
1 5
<210> 4688
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4688
Ser Asp Ile Glu Ile Glu Asn Gly Phe Ile Ser Glu Ser Ser Ser Ile
1 5 10 15
Tyr Ile Leu Asn Lys
20
<210> 4689
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4689
Ser Asp Leu Ala Val Pro Ser Glu Leu Ala Leu Leu Lys
1 5 10
<210> 4690
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4690
Ser Asp Leu Glu Met Gln Tyr Glu Thr Leu Gln Glu Glu Leu Met Ala
1 5 10 15
Leu Lys Lys
<210> 4691
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4691
Ser Asp Leu Glu Val Ala His Tyr Lys
1 5
<210> 4692
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4692
Ser Asp Leu Glu Val Ala His Tyr Lys Leu Lys Pro Arg
1 5 10
<210> 4693
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4693
Ser Asp Asn Cys Glu Asp Thr Pro Glu Ala Gly Tyr Phe Ala Val Ala
1 5 10 15
Val Val Lys
<210> 4694
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4694
Ser Asp Asn Cys Glu Asp Thr Pro Glu Ala Gly Tyr Phe Ala Val Ala
1 5 10 15
Val Val Lys Lys
20
<210> 4695
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4695
Ser Asp Ser Leu Ser Pro Pro Arg
1 5
<210> 4696
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4696
Ser Asp Thr Val Pro Ser Pro Arg
1 5
<210> 4697
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4697
Ser Asp Val Gly Phe Leu Pro Pro Phe Pro Thr Leu Asp Pro Glu Glu
1 5 10 15
Lys
<210> 4698
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4698
Ser Asp Val Met Tyr Thr Asp Trp Lys
1 5
<210> 4699
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4699
Ser Asp Val Met Tyr Thr Asp Trp Lys Lys
1 5 10
<210> 4700
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4700
Ser Asp Val Val Tyr Thr Asp Trp Lys
1 5
<210> 4701
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4701
Ser Asp Val Val Tyr Thr Asp Trp Lys Lys
1 5 10
<210> 4702
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4702
Ser Glu Ala Leu Ala Val Asp Gly Ala Gly Lys Pro Gly Ala Glu Glu
1 5 10 15
Ala Gln Asp Pro Glu Gly Lys
20
<210> 4703
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4703
Ser Glu Ala Tyr Asn Thr Phe Ser Glu Arg
1 5 10
<210> 4704
<211> 34
<212> PRT
<213> Homo sapiens
<400> 4704
Ser Glu Asp Ala Gly Gly Ala Glu Gly Glu Thr Pro His Met Leu Leu
1 5 10 15
Arg Pro His Val Phe Met Pro Glu Val Thr Pro Asp Met Asp Tyr Leu
20 25 30
Pro Arg
<210> 4705
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4705
Ser Glu Asp Cys Phe Ile Leu Asp His Gly Lys
1 5 10
<210> 4706
<211> 25
<212> PRT
<213> Homo sapiens
<400> 4706
Ser Glu Glu Glu Asn Leu Phe Glu Ile Ile Thr Ala Asp Glu Val His
1 5 10 15
Tyr Phe Leu Gln Ala Ala Thr Pro Lys
20 25
<210> 4707
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4707
Ser Glu Glu Phe Leu Ile Ala Gly Lys
1 5
<210> 4708
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4708
Ser Glu Phe Pro Glu Ser Trp Leu Trp Asn Val Glu Asp Leu Lys
1 5 10 15
<210> 4709
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4709
Ser Glu Phe Pro Glu Ser Trp Leu Trp Asn Val Glu Asp Leu Lys Glu
1 5 10 15
Pro Pro Lys
<210> 4710
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4710
Ser Glu Phe Tyr Lys
1 5
<210> 4711
<211> 26
<212> PRT
<213> Homo sapiens
<400> 4711
Ser Glu Gly Ser Ser Val Asn Leu Ser Pro Pro Leu Glu Gln Cys Val
1 5 10 15
Pro Asp Arg Gly Gln Gln Tyr Gln Gly Arg
20 25
<210> 4712
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4712
Ser Glu Ile Asp Asn Val Lys
1 5
<210> 4713
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4713
Ser Glu Ile Asp Asn Val Lys Lys
1 5
<210> 4714
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4714
Ser Glu Ile Leu Ala His Trp Ser Pro Ala Lys
1 5 10
<210> 4715
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4715
Ser Glu Ile Leu Lys
1 5
<210> 4716
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4716
Ser Glu Ile Ser Glu Leu Arg Arg
1 5
<210> 4717
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4717
Ser Glu Ile Thr Glu Leu Arg
1 5
<210> 4718
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4718
Ser Glu Ile Thr Glu Leu Arg Arg
1 5
<210> 4719
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4719
Ser Glu Leu Ile Lys
1 5
<210> 4720
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4720
Ser Glu Leu Leu Lys
1 5
<210> 4721
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4721
Ser Glu Leu Thr Gln Gln Leu Asn Ala Leu Phe Gln Asp Lys
1 5 10
<210> 4722
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4722
Ser Glu Asn Ile Asn His Asn Ser Ala Phe Lys
1 5 10
<210> 4723
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4723
Ser Glu Asn Leu His Val Ser His Ile Leu Gln Lys
1 5 10
<210> 4724
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4724
Ser Glu Pro Ile Pro Glu Ser Asn Asp Gly Pro Val Lys
1 5 10
<210> 4725
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4725
Ser Glu Pro Leu Ile Gly Arg
1 5
<210> 4726
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4726
Ser Glu Thr Glu Ile His Gln Gly Phe Gln His Leu His Gln Leu Phe
1 5 10 15
Ala Lys
<210> 4727
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4727
Ser Glu Val Glu Val Asp Ile His Tyr Cys Gln Gly Lys
1 5 10
<210> 4728
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4728
Ser Glu Val Tyr Gly Pro Met Lys
1 5
<210> 4729
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4729
Ser Glu Tyr Gly Ala Ala Leu Ala Trp Glu Lys
1 5 10
<210> 4730
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4730
Ser Glu Tyr Met Glu Gly Asn Val Arg
1 5
<210> 4731
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4731
Ser Glu Tyr Gln Ala Asp Tyr Glu Ser Leu Arg
1 5 10
<210> 4732
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4732
Ser Phe Asp Tyr His Gln Phe Val Asp Glu Thr Asn Asp Lys
1 5 10
<210> 4733
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4733
Ser Phe Asp Tyr His Gln Phe Val Asp Glu Thr Asn Asp Lys Ile Arg
1 5 10 15
<210> 4734
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4734
Ser Phe Glu Gly Leu Gly Gln Leu Glu Val Leu Thr Leu Asp His Asn
1 5 10 15
Gln Leu Gln Glu Val Lys
20
<210> 4735
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4735
Ser Phe Glu Tyr Lys
1 5
<210> 4736
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4736
Ser Phe Phe Pro Glu Asn Trp Leu Trp Arg
1 5 10
<210> 4737
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4737
Ser Phe Gly Met Thr Pro Val Leu Pro Ala Phe Ala Gly His Val Pro
1 5 10 15
Glu Ala Val Thr Arg
20
<210> 4738
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4738
Ser Phe Leu Glu Asp Ile Arg Lys
1 5
<210> 4739
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4739
Ser Phe Met His Val Asn Thr Asn Ala Asn Phe Tyr Lys
1 5 10
<210> 4740
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4740
Ser Phe Met Leu Leu Ile Leu Glu Arg
1 5
<210> 4741
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4741
Ser Phe Asn Pro Asn Ser Pro Gly Lys
1 5
<210> 4742
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4742
Ser Phe Pro Thr Tyr Cys Gln Gln Lys
1 5
<210> 4743
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4743
Ser Phe Gln Thr Gly Leu Phe Thr Ala Ala Arg
1 5 10
<210> 4744
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4744
Ser Phe Arg Pro Phe Val Pro Arg
1 5
<210> 4745
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4745
Ser Phe Ser Ile Ile Gly Asp Phe Gln Asn Gly Lys Arg
1 5 10
<210> 4746
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4746
Ser Phe Thr Ile Lys Pro Val Gly Phe Lys
1 5 10
<210> 4747
<211> 35
<212> PRT
<213> Homo sapiens
<400> 4747
Ser Phe Val His Leu Glu Pro Met Ser His Glu Leu Pro Cys Gly His
1 5 10 15
Thr Gln Thr Val Gln Ala His Tyr Ile Leu Asn Gly Gly Thr Leu Leu
20 25 30
Gly Leu Lys
35
<210> 4748
<211> 36
<212> PRT
<213> Homo sapiens
<400> 4748
Ser Phe Val His Leu Glu Pro Met Ser His Glu Leu Pro Cys Gly His
1 5 10 15
Thr Gln Thr Val Gln Ala His Tyr Ile Leu Asn Gly Gly Thr Leu Leu
20 25 30
Gly Leu Lys Lys
35
<210> 4749
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4749
Ser Phe Tyr Ala Asn Asn His Cys Ile Gly Thr Asp Leu Asn Arg
1 5 10 15
<210> 4750
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4750
Ser Gly Ala Gly Thr Glu Asp Ser Ala Cys Ile Pro Trp Ala Tyr Tyr
1 5 10 15
Ser Thr Val Asp Gln Val Lys
20
<210> 4751
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4751
Ser Gly Ala Gln Ala Thr Trp Thr Glu Leu Pro Trp Pro His Glu Lys
1 5 10 15
<210> 4752
<211> 25
<212> PRT
<213> Homo sapiens
<400> 4752
Ser Gly Ala Gln Ala Thr Trp Thr Glu Leu Pro Trp Pro His Glu Lys
1 5 10 15
Val Asp Gly Ala Leu Cys Met Glu Lys
20 25
<210> 4753
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4753
Ser Gly Asp Arg Gly Glu Thr Gly Pro Ala Gly Pro Ala Gly Pro Val
1 5 10 15
Gly Pro Val Gly Ala Arg
20
<210> 4754
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4754
Ser Gly Phe Pro Gln Val Ser Met Phe Phe Thr His Thr Phe Pro Lys
1 5 10 15
<210> 4755
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4755
Ser Gly Phe Ser Phe Gly Phe Lys
1 5
<210> 4756
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4756
Ser Gly Gly Ala Ser His Ser Glu Leu Ile His Asn Leu Arg
1 5 10
<210> 4757
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4757
Ser Gly Gly Gly Gly Gly Gly Gly Leu Gly Ser Gly Gly Ser Ile Arg
1 5 10 15
<210> 4758
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4758
Ser Gly Ile Glu Cys Gln Leu Trp Arg
1 5
<210> 4759
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4759
Ser Gly Ile Pro Ile Val Thr Ser Pro Tyr Gln Ile His Phe Thr Lys
1 5 10 15
<210> 4760
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4760
Ser Gly Lys Pro Ala Glu Leu Leu Lys
1 5
<210> 4761
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4761
Ser Gly Lys Tyr Asp Leu Asp Phe Lys
1 5
<210> 4762
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4762
Ser Gly Leu Ser Thr Gly Trp Thr Gln Leu Ser Lys
1 5 10
<210> 4763
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4763
Ser Gly Asn Glu Asn Gly Glu Phe Tyr Leu Arg
1 5 10
<210> 4764
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4764
Ser Gly Asn Met Leu Gly Arg
1 5
<210> 4765
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4765
Ser Gly Gln Ser Glu Asp Arg Gln Pro Val Pro Gly Gln Gln Met Thr
1 5 10 15
Leu Lys
<210> 4766
<211> 25
<212> PRT
<213> Homo sapiens
<400> 4766
Ser Gly Gln Ser Ser Tyr Gly Gln His Ser Ser Gly Ser Ser Gln Ser
1 5 10 15
Ser Gly Tyr Gly Gln His Gly Ser Arg
20 25
<210> 4767
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4767
Ser Gly Ser Asp Glu Val Gln Val Gly Gln Gln Arg
1 5 10
<210> 4768
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4768
Ser Gly Ser Ser Thr Ala Ser Trp Ile Gln Asn Val Asp Thr Lys
1 5 10 15
<210> 4769
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4769
Ser Gly Thr His Thr Leu Pro Val Glu Ser Gly Asp Met Lys
1 5 10
<210> 4770
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4770
Ser Gly Thr Leu Tyr Ser Leu Thr Leu Tyr Gly Leu Arg
1 5 10
<210> 4771
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4771
Ser Gly Thr Ser Glu Phe Leu Asn Lys
1 5
<210> 4772
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4772
Ser Gly Val Gln Met Asn Thr Asn Phe Phe His Glu Ser Gly Leu Glu
1 5 10 15
Ala His Val Ala Leu Lys
20
<210> 4773
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4773
Ser Gly Val Gln Gln Leu Ile Gln Tyr Tyr Gln Asp Gln Lys
1 5 10
<210> 4774
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4774
Ser Gly Val Tyr Gln His Val Thr Gly Glu Met Met Gly Gly His Ala
1 5 10 15
Ile Arg
<210> 4775
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4775
Ser Gly Trp Ala Ile Asp Pro Phe Gly His Ser Pro Thr Met Ala Tyr
1 5 10 15
Leu Leu Asn Arg
20
<210> 4776
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4776
Ser Gly Tyr Leu Leu His Gly Ser Asn Glu Ile Thr Cys Asn Arg
1 5 10 15
<210> 4777
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4777
Ser His Ala Leu Gln Leu Asn Asn Arg
1 5
<210> 4778
<211> 27
<212> PRT
<213> Homo sapiens
<400> 4778
Ser His Cys Ile Ala Glu Val Glu Asn Asp Glu Met Pro Ala Asp Leu
1 5 10 15
Pro Ser Leu Ala Ala Asp Phe Val Glu Ser Lys
20 25
<210> 4779
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4779
Ser His Glu Phe His Ala Ile Asn Gly Met Ile Tyr Ser Leu Pro Gly
1 5 10 15
Leu Lys
<210> 4780
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4780
Ser His Lys Pro Leu Asn Met Gly Lys
1 5
<210> 4781
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4781
Ser His Leu Ile Ile Ala Gln Val Ala Lys
1 5 10
<210> 4782
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4782
Ser His Ser Ala His Phe Phe Glu Phe Leu Thr Lys
1 5 10
<210> 4783
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4783
Ser Ile Ala Ala Ala Thr Ser Ala Leu Val Lys
1 5 10
<210> 4784
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4784
Ser Ile Ala Gln Tyr Trp Leu Gly Cys Pro Ala Pro Gly His Leu
1 5 10 15
<210> 4785
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4785
Ser Ile Asp Asp Leu Glu Glu Lys
1 5
<210> 4786
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4786
Ser Ile Asp Val Ala Cys His Pro Gly Tyr Ala Leu Pro Lys
1 5 10
<210> 4787
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4787
Ser Ile Glu Glu Val Leu Arg
1 5
<210> 4788
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4788
Ser Ile Glu His Leu Lys
1 5
<210> 4789
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4789
Ser Ile Glu Val Phe Gly Gln Phe Asn Gly Lys
1 5 10
<210> 4790
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4790
Ser Ile Glu Val Phe Gly Gln Phe Asn Gly Lys Arg
1 5 10
<210> 4791
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4791
Ser Ile Glu Val Lys
1 5
<210> 4792
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4792
Ser Ile Gly Asp Leu Asp Leu Lys
1 5
<210> 4793
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4793
Ser Ile Ile Gln Glu Lys
1 5
<210> 4794
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4794
Ser Ile Leu Asp Lys
1 5
<210> 4795
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4795
Ser Ile Leu Glu Asn Leu Arg
1 5
<210> 4796
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4796
Ser Ile Leu Phe Leu Gly Lys
1 5
<210> 4797
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4797
Ser Ile Leu Pro Lys
1 5
<210> 4798
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4798
Ser Ile Leu Gln Glu Lys
1 5
<210> 4799
<211> 28
<212> PRT
<213> Homo sapiens
<400> 4799
Ser Ile Leu Gln Met Ser Leu Asp His His Ile Val Thr Pro Leu Thr
1 5 10 15
Ser Leu Val Ile Glu Asn Glu Ala Gly Asp Glu Arg
20 25
<210> 4800
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4800
Ser Ile Pro Gln Val Ser Pro Val Arg
1 5
<210> 4801
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4801
Ser Ile Pro Gln Val Ser Pro Val Arg Arg
1 5 10
<210> 4802
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4802
Ser Ile Gln Asn Asn Val Arg
1 5
<210> 4803
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4803
Ser Ile Arg Pro Gly Leu Ser Pro Tyr Arg
1 5 10
<210> 4804
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4804
Ser Ile Ser Ala Ala Leu Glu His Lys
1 5
<210> 4805
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4805
Ser Ile Ser Ile Ser Val Ala Arg
1 5
<210> 4806
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4806
Ser Ile Ser Leu Ile Arg
1 5
<210> 4807
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4807
Ser Ile Ser Leu Leu Arg
1 5
<210> 4808
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4808
Ser Ile Ser Leu Pro Tyr Arg
1 5
<210> 4809
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4809
Ser Ile Thr Leu Phe Val Gln Glu Asp Arg
1 5 10
<210> 4810
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4810
Ser Ile Val Glu Lys
1 5
<210> 4811
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4811
Ser Ile Val Asn Tyr Lys Pro Lys
1 5
<210> 4812
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4812
Ser Ile Val Pro Gln Gly Gly Ser His Ser Leu Arg
1 5 10
<210> 4813
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4813
Ser Ile Val Ser Ala Leu Lys
1 5
<210> 4814
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4814
Ser Ile Val Ser Ala Leu Lys Arg
1 5
<210> 4815
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4815
Ser Ile Tyr Gly Glu Lys
1 5
<210> 4816
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4816
Ser Ile Tyr Gly Glu Lys Phe Glu Asp Glu Asn Phe Ile Leu Lys
1 5 10 15
<210> 4817
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4817
Ser Ile Tyr Lys Pro Gly Gln Thr Val Lys
1 5 10
<210> 4818
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4818
Ser Lys Ala Glu Ala Glu Ser Leu Tyr Gln Ser Lys
1 5 10
<210> 4819
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4819
Ser Lys Ala Ile Gly Tyr Leu Asn Thr Gly Tyr Gln Arg
1 5 10
<210> 4820
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4820
Ser Lys Asp His Glu Glu Leu Ser Leu Val Ala Ser Glu Ala Val Arg
1 5 10 15
<210> 4821
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4821
Ser Lys Glu Glu Ala Glu Ala Leu Tyr His Ser Lys
1 5 10
<210> 4822
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4822
Ser Lys Glu Glu Ser His Glu Gln Ser Ala Glu Gln Gly Lys
1 5 10
<210> 4823
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4823
Ser Lys Glu Phe Met Glu Glu Val Ile Gln Arg
1 5 10
<210> 4824
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4824
Ser Lys Glu Phe Gln Leu Phe Ser Ser Pro His Gly Lys
1 5 10
<210> 4825
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4825
Ser Lys Glu Leu Thr Thr Glu Ile Asp Asn Asn Ile Glu Gln Ile Ser
1 5 10 15
Ser Tyr Lys
<210> 4826
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4826
Ser Lys Glu Gln Leu Thr Pro Leu Ile Lys
1 5 10
<210> 4827
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4827
Ser Lys Phe Ser Pro Glu Asn Thr Arg
1 5
<210> 4828
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4828
Ser Lys Ile Gln Lys
1 5
<210> 4829
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4829
Ser Lys Ile Tyr Met Ala Asp Leu Glu Ser Ala Leu His Tyr Ile Leu
1 5 10 15
Arg
<210> 4830
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4830
Ser Lys Leu Pro Gly Ile Val Ala Glu Gly Arg
1 5 10
<210> 4831
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4831
Ser Lys Leu Gln Lys
1 5
<210> 4832
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4832
Ser Lys Pro Thr Val Ser Ser Ser Met Glu Phe Lys
1 5 10
<210> 4833
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4833
Ser Leu Ala Asp Glu Leu Ala Leu Val Asp Val Leu Glu Asp Lys
1 5 10 15
<210> 4834
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4834
Ser Leu Ala Glu Leu Gly Gly His Leu Asp Gln Gln Val Glu Glu Phe
1 5 10 15
Arg
<210> 4835
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4835
Ser Leu Ala Glu Leu Gly Gly His Leu Asp Gln Gln Val Glu Glu Phe
1 5 10 15
Arg Arg
<210> 4836
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4836
Ser Leu Ala Leu Gly Thr Phe Ala His Thr Pro Ala Leu Ala Ser Leu
1 5 10 15
Gly Leu Ser Asn Asn Arg
20
<210> 4837
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4837
Ser Leu Ala Pro Thr Ala Ala Ala Lys
1 5
<210> 4838
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4838
Ser Leu Ala Pro Thr Ala Ala Ala Lys Arg
1 5 10
<210> 4839
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4839
Ser Leu Ala Pro Tyr Ala Gln Asp Thr Gln Glu Lys
1 5 10
<210> 4840
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4840
Ser Leu Asp Glu His Tyr His Ile Arg
1 5
<210> 4841
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4841
Ser Leu Asp Glu Ile Ser Gln Pro Ala Gln Glu Leu Lys
1 5 10
<210> 4842
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4842
Ser Leu Asp Phe Thr Glu Leu Asp Val Ala Ala Glu Lys
1 5 10
<210> 4843
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4843
Ser Leu Asp Phe Thr Glu Leu Asp Val Ala Ala Glu Lys Ile Asp Arg
1 5 10 15
<210> 4844
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4844
Ser Leu Asp Leu Asp Ser Ile Ile Ala Glu Val Lys
1 5 10
<210> 4845
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4845
Ser Leu Asp Leu Ser Lys
1 5
<210> 4846
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4846
Ser Leu Glu Ala Ala Ser Glu Lys
1 5
<210> 4847
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4847
Ser Leu Glu Cys Leu His Pro Gly Thr Lys
1 5 10
<210> 4848
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4848
Ser Leu Glu Asp Lys Thr Glu Arg
1 5
<210> 4849
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4849
Ser Leu Glu Asp Leu Gln Leu Thr His Asn Lys
1 5 10
<210> 4850
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4850
Ser Leu Glu Val Thr Phe Thr Pro Val Ile Glu Asp Ile Gly Lys
1 5 10 15
<210> 4851
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4851
Ser Leu Glu Tyr Leu Asp Leu Ser Phe Asn Gln Ile Ala Arg
1 5 10
<210> 4852
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4852
Ser Leu Phe Thr Asp Leu Glu Ala Glu Asn Asp Val Leu His Cys Val
1 5 10 15
Ala Phe Ala Val Pro Lys
20
<210> 4853
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4853
Ser Leu Phe Thr Asp Leu Val Ala Glu Lys
1 5 10
<210> 4854
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4854
Ser Leu Phe Trp Glu Asn Ser His Leu Leu Val Asn Ser Phe Ala Asp
1 5 10 15
Asn Thr Arg Arg
20
<210> 4855
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4855
Ser Leu Gly Phe Cys Asp Thr Thr Asn Lys
1 5 10
<210> 4856
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4856
Ser Leu Gly Asn Val Ile Met Val Cys Arg
1 5 10
<210> 4857
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4857
Ser Leu Gly Trp Leu Lys
1 5
<210> 4858
<211> 29
<212> PRT
<213> Homo sapiens
<400> 4858
Ser Leu His Asp Pro Asp Gly Leu Val Ala Thr Tyr Ile Ser Glu Val
1 5 10 15
His Glu His Asp Gly His Leu Tyr Leu Gly Ser Phe Arg
20 25
<210> 4859
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4859
Ser Leu His Met Tyr Ala Asn Arg
1 5
<210> 4860
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4860
Ser Leu His Thr Leu Phe Gly Asp Lys
1 5
<210> 4861
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4861
Ser Leu His Thr Leu Phe Gly Asp Lys Leu Cys Thr Val Ala Thr Leu
1 5 10 15
Arg
<210> 4862
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4862
Ser Leu Lys Val Asn Cys Lys
1 5
<210> 4863
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4863
Ser Leu Leu Asp Gly Arg
1 5
<210> 4864
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4864
Ser Leu Leu His Gly Asp Phe His Ala Phe Ser Ala Gly Pro Gly Leu
1 5 10 15
Phe Ser Tyr Ile Arg
20
<210> 4865
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4865
Ser Leu Leu His Ile Lys
1 5
<210> 4866
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4866
Ser Leu Leu His Leu Lys
1 5
<210> 4867
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4867
Ser Leu Leu His Thr Leu Ala Leu Pro Ser Pro Lys
1 5 10
<210> 4868
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4868
Ser Leu Leu Pro Lys
1 5
<210> 4869
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4869
Ser Leu Leu Gln Pro Asn Lys
1 5
<210> 4870
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4870
Ser Leu Leu Gln Arg Val Arg
1 5
<210> 4871
<211> 25
<212> PRT
<213> Homo sapiens
<400> 4871
Ser Leu Leu Ser Asn Val Glu Gly Asp Asn Ala Val Pro Met Gln His
1 5 10 15
Asn Asn Arg Pro Thr Gln Pro Leu Lys
20 25
<210> 4872
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4872
Ser Leu Met Leu His Tyr Glu Phe Leu Gln Arg
1 5 10
<210> 4873
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4873
Ser Leu Met Leu Ser Tyr Asn Ala Ile Thr His Leu Pro Ala Gly Ile
1 5 10 15
Phe Arg
<210> 4874
<211> 49
<212> PRT
<213> Homo sapiens
<400> 4874
Ser Leu Met Pro Phe Ser Pro Tyr Glu Pro Leu Asn Phe His Ala Met
1 5 10 15
Phe Gln Pro Phe Leu Glu Met Ile His Glu Ala Gln Gln Ala Met Asp
20 25 30
Ile His Phe His Ser Pro Ala Phe Gln His Pro Pro Thr Glu Phe Ile
35 40 45
Arg
<210> 4875
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4875
Ser Leu Asn Glu Glu Ala Val Lys
1 5
<210> 4876
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4876
Ser Leu Asn Glu Glu Ala Val Lys Lys
1 5
<210> 4877
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4877
Ser Leu Asn Asn Gln Phe Ala Ser Phe Ile Asp Lys
1 5 10
<210> 4878
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4878
Ser Leu Asn Asn Gln Phe Ala Ser Phe Ile Asp Lys Val Arg
1 5 10
<210> 4879
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4879
Ser Leu Asn Pro Asn Arg
1 5
<210> 4880
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4880
Ser Leu Pro Ala Pro Trp Leu Ser Met Ala Pro Val Ser Trp Ile Thr
1 5 10 15
Pro Gly Leu Lys
20
<210> 4881
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4881
Ser Leu Pro Glu Gly Val Ala Asn Gly Ile Glu Val Tyr Ser Thr Lys
1 5 10 15
<210> 4882
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4882
Ser Leu Pro Gly Phe Ser His Met Ala Pro Leu Pro Lys
1 5 10
<210> 4883
<211> 37
<212> PRT
<213> Homo sapiens
<400> 4883
Ser Leu Pro Met Asp His Pro Asp Ser Ser Gln His Gly Pro Pro Phe
1 5 10 15
Glu Gly Gln Ser Gln Val Gln Pro Pro Pro Ser Gln Glu Ala Thr Pro
20 25 30
Leu Gln Gln Glu Lys
35
<210> 4884
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4884
Ser Leu Pro Val Ser Asp Ser Val Leu Ser Gly Phe Glu Gln Arg
1 5 10 15
<210> 4885
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4885
Ser Leu Gln Glu Met Lys
1 5
<210> 4886
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4886
Ser Leu Gln Glu Arg Ile Lys
1 5
<210> 4887
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4887
Ser Leu Gln Gly Asp Lys Leu Glu Val Ser Leu Lys
1 5 10
<210> 4888
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4888
Ser Leu Gln Leu His Leu Lys
1 5
<210> 4889
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4889
Ser Leu Ser Gly Thr Ala Phe Gly Gly Phe Leu Met Phe Lys
1 5 10
<210> 4890
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4890
Ser Leu Ser Leu Ile Arg
1 5
<210> 4891
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4891
Ser Leu Ser Asn Val Ile Ala His Glu Ile Ser His Ser Trp Thr Gly
1 5 10 15
Asn Leu Val Thr Asn Lys
20
<210> 4892
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4892
Ser Leu Ser Ser Met Thr Arg
1 5
<210> 4893
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4893
Ser Leu Thr Asn Asp Trp Glu Asp His Leu Ala Val Lys
1 5 10
<210> 4894
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4894
Ser Leu Thr Pro His Phe Ala Arg
1 5
<210> 4895
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4895
Ser Leu Val Gly Leu Gly Gly Thr Lys
1 5
<210> 4896
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4896
Ser Leu Trp Asp Phe Leu Lys
1 5
<210> 4897
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4897
Ser Leu Trp Asp Phe Leu Lys Leu Asp Val Thr Thr Ser Ile Gly Arg
1 5 10 15
<210> 4898
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4898
Ser Leu Tyr Gly Glu Lys
1 5
<210> 4899
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4899
Ser Leu Tyr Asn Leu Gly Gly Ser Lys Arg
1 5 10
<210> 4900
<211> 21
<212> PRT
<213> Homo sapiens
<400> 4900
Ser Leu Tyr Val Ser Ala Thr Val Ile Leu His Ser Gly Ser Asp Met
1 5 10 15
Val Gln Ala Glu Arg
20
<210> 4901
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4901
Ser Met Asp Glu Phe Leu Leu Lys
1 5
<210> 4902
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4902
Ser Met Gly Gly Lys Glu Asp Leu Ile Trp Glu Leu Leu Asn Gln Ala
1 5 10 15
Gln Glu His Phe Gly Lys
20
<210> 4903
<211> 39
<212> PRT
<213> Homo sapiens
<400> 4903
Ser Met Gln Gly Gly Leu Val Gly Asn Asp Glu Thr Val Ala Leu Thr
1 5 10 15
Ala Phe Val Thr Ile Ala Leu His His Gly Leu Ala Val Phe Gln Asp
20 25 30
Glu Gly Ala Glu Pro Leu Lys
35
<210> 4904
<211> 41
<212> PRT
<213> Homo sapiens
<400> 4904
Ser Met Gln Gly Gly Leu Val Gly Asn Asp Glu Thr Val Ala Leu Thr
1 5 10 15
Ala Phe Val Thr Ile Ala Leu His His Gly Leu Ala Val Phe Gln Asp
20 25 30
Glu Gly Ala Glu Pro Leu Lys Gln Arg
35 40
<210> 4905
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4905
Ser Asn Ala Leu Asp Ile Ile Phe Gln Thr Asp Leu Thr Gly Gln Lys
1 5 10 15
<210> 4906
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4906
Ser Asn Phe Ala Glu Ala Leu Ala Ala His Lys
1 5 10
<210> 4907
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4907
Ser Asn Phe Leu Asn Cys Tyr Val Ser Gly Phe His Pro Ser Asp Ile
1 5 10 15
Glu Val Asp Leu Leu Lys
20
<210> 4908
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4908
Ser Asn Leu Pro Ile Phe Leu Pro Arg
1 5
<210> 4909
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4909
Ser Asn Thr Val Ala Ser Leu His Thr Glu Lys
1 5 10
<210> 4910
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4910
Ser Asn Val Asp Met Asp Phe Glu Val Glu Asn Ala Val Leu Gly Lys
1 5 10 15
<210> 4911
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4911
Ser Asn Val Asp Met Asp Phe Glu Val Glu Asn Ala Val Leu Gly Lys
1 5 10 15
Asp Phe Lys
<210> 4912
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4912
Ser Asn Val Ser Asp Ala Val Ala Gln Ser Thr Arg
1 5 10
<210> 4913
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4913
Ser Pro Ala Phe Thr Asp Leu His Leu Arg
1 5 10
<210> 4914
<211> 28
<212> PRT
<213> Homo sapiens
<400> 4914
Ser Pro Cys Tyr Gly Tyr Gln Trp Val Ser Glu Glu His Glu Glu Ala
1 5 10 15
His His Thr Ala Tyr Leu Val Phe Ser Pro Ser Lys
20 25
<210> 4915
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4915
Ser Pro Asp Gly Asp Ser Ser Leu Ala Ala Ser Glu Arg
1 5 10
<210> 4916
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4916
Ser Pro Asp Val Ile Asn Gly Ser Pro Ile Ser Gln Lys
1 5 10
<210> 4917
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4917
Ser Pro Glu Leu Gln Ala Glu Ala Lys
1 5
<210> 4918
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4918
Ser Pro Glu Gln Gln Glu Thr Val Leu Asp Gly Asn Leu Ile Ile Arg
1 5 10 15
<210> 4919
<211> 25
<212> PRT
<213> Homo sapiens
<400> 4919
Ser Pro Glu Ser Asp Ser Ile Gln Trp Phe His Asn Gly Asn Leu Ile
1 5 10 15
Pro Thr His Thr Gln Pro Ser Tyr Arg
20 25
<210> 4920
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4920
Ser Pro Phe Ala Leu Arg Pro Leu Arg
1 5
<210> 4921
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4921
Ser Pro Phe Asn Asp Arg
1 5
<210> 4922
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4922
Ser Pro Phe Asn Asn Arg
1 5
<210> 4923
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4923
Ser Pro Phe Ser Val Ala Val Ser Pro Ser Leu Asp Leu Ser Lys
1 5 10 15
<210> 4924
<211> 29
<212> PRT
<213> Homo sapiens
<400> 4924
Ser Pro His Trp Gly Ser Thr Tyr Ser Val Ser Val Val Glu Thr Asp
1 5 10 15
Tyr Asp Gln Tyr Ala Leu Leu Tyr Ser Gln Gly Ser Lys
20 25
<210> 4925
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4925
Ser Pro Leu Phe Met Gly Lys
1 5
<210> 4926
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4926
Ser Pro Leu Gly Leu Lys
1 5
<210> 4927
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4927
Ser Pro Leu Asn Asp Phe Gln Val Leu Arg
1 5 10
<210> 4928
<211> 26
<212> PRT
<213> Homo sapiens
<400> 4928
Ser Pro Pro Glu Ile Ser His Gly Val Val Ala His Met Ser Asp Ser
1 5 10 15
Tyr Gln Tyr Gly Glu Glu Val Thr Tyr Lys
20 25
<210> 4929
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4929
Ser Pro Pro Gly Val Cys Ser Arg Asp Pro Thr Pro Glu Gln Thr His
1 5 10 15
Arg
<210> 4930
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4930
Ser Pro Pro His Leu Ile Lys
1 5
<210> 4931
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4931
Ser Pro Arg Pro Ser Ser Tyr Lys
1 5
<210> 4932
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4932
Ser Pro Ser Gln Ala Asp Ile Asn Lys
1 5
<210> 4933
<211> 52
<212> PRT
<213> Homo sapiens
<400> 4933
Ser Pro Ser Ser Ser Gln Pro Leu Pro Gln Val Pro Ala Pro Ala Gln
1 5 10 15
Ser Gln Thr Gln Phe His Val Gln Pro Gln Pro Gln Pro Lys Pro Gln
20 25 30
Val Gln Leu His Val Gln Ser Gln Thr Gln Pro Val Ser Leu Ala Asn
35 40 45
Thr Gln Pro Arg
50
<210> 4934
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4934
Ser Pro Val Gly Val Gln Pro Ile Leu Asn Glu His Thr Phe Cys Ala
1 5 10 15
Gly Met Ser Lys
20
<210> 4935
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4935
Ser Pro Val Thr Leu Leu Ala Ala Val Met Ser Leu Pro Glu Glu His
1 5 10 15
Asn Lys
<210> 4936
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4936
Ser Pro Tyr Ile Asp Lys
1 5
<210> 4937
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4937
Ser Pro Tyr Ile Asp Lys Ile Thr His Tyr Asn Tyr Leu Ile Leu Ser
1 5 10 15
Lys
<210> 4938
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4938
Ser Pro Tyr Gln Leu Val Leu Gln His Ser Arg
1 5 10
<210> 4939
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4939
Ser Gln Ala Ile Ala Thr Lys Lys
1 5
<210> 4940
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4940
Ser Gln Asp Glu Ala Pro Gly Asp Pro Ile Gln Gln Leu Asn Leu Lys
1 5 10 15
<210> 4941
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4941
Ser Gln Asp Ile Leu Leu Ser Val Glu Asn Thr Val Ile Tyr Arg
1 5 10 15
<210> 4942
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4942
Ser Gln Glu Phe Leu Glu Asp Ala Asp Arg Lys
1 5 10
<210> 4943
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4943
Ser Gln Phe Leu Ile Lys
1 5
<210> 4944
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4944
Ser Gln His Leu Asp Asn Phe Ser Asn Gln Ile Gly Lys
1 5 10
<210> 4945
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4945
Ser Gln Ile His Asp Ile Val Leu Val Gly Gly Ser Thr Arg
1 5 10
<210> 4946
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4946
Ser Gln Ile Leu Lys
1 5
<210> 4947
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4947
Ser Gln Leu Ile Lys
1 5
<210> 4948
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4948
Ser Gln Leu Leu Lys
1 5
<210> 4949
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4949
Ser Gln Leu Leu Pro Val Gly Arg
1 5
<210> 4950
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4950
Ser Gln Leu Val Tyr Gln Ser Arg
1 5
<210> 4951
<211> 44
<212> PRT
<213> Homo sapiens
<400> 4951
Ser Gln Pro Gly Ser Thr Pro Leu His Gly Gln Pro Leu Val Val Leu
1 5 10 15
Gln Gly Asn Asn Ile Ile Leu Glu His His Val Ala Gln Glu Pro Ser
20 25 30
Pro Gly Gln Pro Ser Thr Phe Ile Val Pro Phe Arg
35 40
<210> 4952
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4952
Ser Gln Pro Met Gly Leu Trp Arg
1 5
<210> 4953
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4953
Ser Gln Pro Ser Gln Pro Ser Asp His His Glu Thr Pro Pro Ala Ala
1 5 10 15
Pro Asp Arg
<210> 4954
<211> 25
<212> PRT
<213> Homo sapiens
<400> 4954
Ser Gln Pro Ser Gln Pro Ser Asp His His Glu Thr Pro Pro Ala Ala
1 5 10 15
Pro Asp Arg Asn Pro Gln Asn Ile Arg
20 25
<210> 4955
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4955
Ser Gln Val Glu Pro Glu Thr Arg
1 5
<210> 4956
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4956
Ser Gln Val Ile Ala Glu Lys
1 5
<210> 4957
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4957
Ser Gln Tyr Glu Gln Leu Ala Glu Gln Asn Arg
1 5 10
<210> 4958
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4958
Ser Gln Tyr Glu Gln Leu Ala Glu Gln Asn Arg Lys
1 5 10
<210> 4959
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4959
Ser Arg Ile Glu Val Leu Lys
1 5
<210> 4960
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4960
Ser Arg Ile Asn Pro Lys
1 5
<210> 4961
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4961
Ser Arg Leu Asp Thr Leu Ala Gln Glu Val Ala Leu Leu Lys
1 5 10
<210> 4962
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4962
Ser Arg Leu Ile Val Tyr Leu Ala Leu Leu Gly Ser Glu Asn Arg
1 5 10 15
<210> 4963
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4963
Ser Arg Pro Glu Phe Met Leu Pro Val His Phe Tyr Gly Lys
1 5 10
<210> 4964
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4964
Ser Arg Pro Ser Gln Val Leu Asp Ser Pro Phe Pro Thr Gly Ser Ala
1 5 10 15
Phe Gly Phe Ser Leu Arg
20
<210> 4965
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4965
Ser Arg Val Thr Ile Ser Val Asp Lys
1 5
<210> 4966
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4966
Ser Arg Trp Pro Ala Val Phe Thr Arg
1 5
<210> 4967
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4967
Ser Ser Ala Leu Asp Met Glu Asn Phe Arg
1 5 10
<210> 4968
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4968
Ser Ser Ala Leu Asp Met Glu Asn Phe Arg Thr Glu Val Asn Val Leu
1 5 10 15
Pro Gly Ala Lys
20
<210> 4969
<211> 17
<212> PRT
<213> Homo sapiens
<400> 4969
Ser Ser Phe Thr Val Gln Asp Leu Lys Pro Phe Thr Glu Tyr Val Phe
1 5 10 15
Arg
<210> 4970
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4970
Ser Ser Phe Val Ala Pro Leu Glu Lys
1 5
<210> 4971
<211> 14
<212> PRT
<213> Homo sapiens
<400> 4971
Ser Ser Phe Tyr Val Asn Gly Leu Thr Leu Gly Gly Gln Lys
1 5 10
<210> 4972
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4972
Ser Ser Gly Ala Phe Trp Lys
1 5
<210> 4973
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4973
Ser Ser Gly Gln Trp Gln Thr Pro Gly Ala Thr Arg
1 5 10
<210> 4974
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4974
Ser Ser Gly Ser Leu Leu Asn Asn Ala Ile Lys
1 5 10
<210> 4975
<211> 41
<212> PRT
<213> Homo sapiens
<400> 4975
Ser Ser Gly Ser Leu Leu Asn Asn Ala Ile Lys Gly Gly Val Glu Asp
1 5 10 15
Glu Val Thr Leu Ser Ala Tyr Ile Thr Ile Ala Leu Leu Glu Ile Pro
20 25 30
Leu Thr Val Thr His Pro Val Val Arg
35 40
<210> 4976
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4976
Ser Ser Gly Trp His Phe Val Val Lys
1 5
<210> 4977
<211> 20
<212> PRT
<213> Homo sapiens
<400> 4977
Ser Ser Ile Asp Ile Glu Asn Gly Phe Ile Ser Glu Ser Gln Tyr Thr
1 5 10 15
Tyr Ala Leu Lys
20
<210> 4978
<211> 22
<212> PRT
<213> Homo sapiens
<400> 4978
Ser Ser Ile Asp Ile Glu Asn Gly Phe Ile Ser Glu Ser Gln Tyr Thr
1 5 10 15
Tyr Ala Leu Lys Glu Lys
20
<210> 4979
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4979
Ser Ser Ile Ile Ile Arg
1 5
<210> 4980
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4980
Ser Ser Ile Ile Lys
1 5
<210> 4981
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4981
Ser Ser Ile Leu Lys
1 5
<210> 4982
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4982
Ser Ser Leu Ile Lys
1 5
<210> 4983
<211> 5
<212> PRT
<213> Homo sapiens
<400> 4983
Ser Ser Leu Leu Lys
1 5
<210> 4984
<211> 6
<212> PRT
<213> Homo sapiens
<400> 4984
Ser Ser Leu Leu Leu Arg
1 5
<210> 4985
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4985
Ser Ser Leu Leu Leu Val Leu Phe Arg
1 5
<210> 4986
<211> 13
<212> PRT
<213> Homo sapiens
<400> 4986
Ser Ser Leu Ser Val Pro Tyr Val Ile Val Pro Leu Lys
1 5 10
<210> 4987
<211> 10
<212> PRT
<213> Homo sapiens
<400> 4987
Ser Ser Met Ala Val His Ser Leu Phe Lys
1 5 10
<210> 4988
<211> 12
<212> PRT
<213> Homo sapiens
<400> 4988
Ser Ser Asn Leu Ile Ile Leu Glu Glu His Leu Lys
1 5 10
<210> 4989
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4989
Ser Ser Asn Asn Pro His Ser Pro Ile Val Glu Glu Phe Gln Val Pro
1 5 10 15
Tyr Asn Lys
<210> 4990
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4990
Ser Ser Asn Thr Tyr Thr Leu Thr Asp Val Arg
1 5 10
<210> 4991
<211> 18
<212> PRT
<213> Homo sapiens
<400> 4991
Ser Ser Pro Ala Ala Lys Pro Gly Ser Thr Pro Ser Arg Pro Ser Ser
1 5 10 15
Ala Lys
<210> 4992
<211> 19
<212> PRT
<213> Homo sapiens
<400> 4992
Ser Ser Pro Val Val Ile Asp Ala Ser Thr Ala Ile Asp Ala Pro Ser
1 5 10 15
Asn Leu Arg
<210> 4993
<211> 8
<212> PRT
<213> Homo sapiens
<400> 4993
Ser Ser Pro Tyr Tyr Ala Leu Arg
1 5
<210> 4994
<211> 11
<212> PRT
<213> Homo sapiens
<400> 4994
Ser Ser Gln Glu Ser Tyr Ala His Gly Thr Lys
1 5 10
<210> 4995
<211> 7
<212> PRT
<213> Homo sapiens
<400> 4995
Ser Ser Gln Met Glu Thr Lys
1 5
<210> 4996
<211> 23
<212> PRT
<213> Homo sapiens
<400> 4996
Ser Ser Gln Thr Val Ala Val His His Pro Gln Tyr Gly Phe Ser Val
1 5 10 15
Gln Gly Glu Tyr Gln Gly Arg
20
<210> 4997
<211> 15
<212> PRT
<213> Homo sapiens
<400> 4997
Ser Ser Ser Asn Glu Glu Val Met Phe Leu Thr Val Gln Val Lys
1 5 10 15
<210> 4998
<211> 9
<212> PRT
<213> Homo sapiens
<400> 4998
Ser Ser Ser Gln Glu Leu Gly Leu Lys
1 5
<210> 4999
<211> 16
<212> PRT
<213> Homo sapiens
<400> 4999
Ser Ser Ser Tyr Ser Lys Gln Phe Thr Ser Ser Thr Ser Tyr Asn Arg
1 5 10 15
<210> 5000
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5000
Ser Ser Thr Gly Pro Gly Glu Gln Leu Arg
1 5 10
<210> 5001
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5001
Ser Ser Thr Pro Glu Glu Val Lys
1 5
<210> 5002
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5002
Ser Ser Thr Pro Glu Glu Val Lys Lys
1 5
<210> 5003
<211> 30
<212> PRT
<213> Homo sapiens
<400> 5003
Ser Ser Thr Ser Pro Thr Thr Asn Val Leu Leu Ser Pro Leu Ser Val
1 5 10 15
Ala Thr Ala Leu Ser Ala Leu Ser Leu Gly Ala Glu Gln Arg
20 25 30
<210> 5004
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5004
Ser Ser Thr Thr Lys Pro Pro Phe Lys Pro His Gly Ser Arg
1 5 10
<210> 5005
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5005
Ser Ser Val Ala Ala Met His Trp Met Asp Gly Ser Val Val Thr Arg
1 5 10 15
<210> 5006
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5006
Ser Ser Trp Ser Met Arg
1 5
<210> 5007
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5007
Ser Thr Ala Ala Met Ser Thr Tyr Thr Gly Ile Phe Thr Asp Gln Val
1 5 10 15
Leu Ser Val Leu Lys
20
<210> 5008
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5008
Ser Thr Ala Ala Met Ser Thr Tyr Thr Gly Ile Phe Thr Asp Gln Val
1 5 10 15
Leu Ser Val Leu Lys Gly Glu Glu
20
<210> 5009
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5009
Ser Thr Ala Thr Ile Ser Gly Leu Lys Pro Gly Val Asp Tyr Thr Ile
1 5 10 15
Thr Val Tyr Ala Val Thr Gly Arg
20
<210> 5010
<211> 39
<212> PRT
<213> Homo sapiens
<400> 5010
Ser Thr Ala Thr Ile Ser Gly Leu Lys Pro Gly Val Asp Tyr Thr Ile
1 5 10 15
Thr Val Tyr Ala Val Thr Gly Arg Gly Asp Ser Pro Ala Ser Ser Lys
20 25 30
Pro Ile Ser Ile Asn Tyr Arg
35
<210> 5011
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5011
Ser Thr Asp Thr Ser Cys Val Asn Pro Pro Thr Val Gln Asn Ala His
1 5 10 15
Ile Leu Ser Arg
20
<210> 5012
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5012
Ser Thr Asp Tyr Gly Ile Phe Gln Ile Asn Ser Arg
1 5 10
<210> 5013
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5013
Ser Thr Gly Gly Ala Pro Thr Phe Asn Val Thr Val Thr Lys
1 5 10
<210> 5014
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5014
Ser Thr Gly Ser Trp Ser Thr Leu Lys
1 5
<210> 5015
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5015
Ser Thr His Gln Ala Ala Ile Val Ser Lys
1 5 10
<210> 5016
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5016
Ser Thr His Thr Leu Asp Leu Ser Arg
1 5
<210> 5017
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5017
Ser Thr Lys Glu Ile Pro Asp Glu Ile Ser Ile Leu Leu Leu Gly Val
1 5 10 15
Ala His Phe Lys
20
<210> 5018
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5018
Ser Thr Leu Glu Pro Val Glu Lys
1 5
<210> 5019
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5019
Ser Thr Met Lys Pro Val Gln Lys
1 5
<210> 5020
<211> 25
<212> PRT
<213> Homo sapiens
<400> 5020
Ser Thr Gln Asp Thr Val Ile Ala Leu Asp Ala Leu Ser Ala Tyr Trp
1 5 10 15
Ile Ala Ser His Thr Thr Glu Glu Arg
20 25
<210> 5021
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5021
Ser Thr Ser Ile Val Ile Met Leu Thr Asp Gly Asp Ala Asn Val Gly
1 5 10 15
Glu Ser Arg Pro Glu Lys
20
<210> 5022
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5022
Ser Thr Ser Pro Pro Lys Gln Ala Glu Ala Val Leu Lys
1 5 10
<210> 5023
<211> 35
<212> PRT
<213> Homo sapiens
<400> 5023
Ser Thr Thr Asp Asn Asp Ile Ala Leu Leu His Leu Ala Gln Pro Ala
1 5 10 15
Thr Leu Ser Gln Thr Ile Val Pro Ile Cys Leu Pro Asp Ser Gly Leu
20 25 30
Ala Glu Arg
35
<210> 5024
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5024
Ser Thr Thr Pro Asp Ile Thr Gly Tyr Arg
1 5 10
<210> 5025
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5025
Ser Thr Val Glu Gly Ile Gln Ala Ser Val Lys
1 5 10
<210> 5026
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5026
Ser Thr Val Glu Ile Phe Lys
1 5
<210> 5027
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5027
Ser Thr Val Glu Leu Phe Lys
1 5
<210> 5028
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5028
Ser Thr Val Glu Leu Phe Lys Phe Gln Glu Glu Glu Lys
1 5 10
<210> 5029
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5029
Ser Thr Val Leu Thr Ile Pro Glu Ile Ile Ile Lys
1 5 10
<210> 5030
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5030
Ser Thr Val Ser Ser Leu Leu Gln Lys
1 5
<210> 5031
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5031
Ser Val Ala Pro His Ala Pro Ala Ser Pro Ala Arg
1 5 10
<210> 5032
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5032
Ser Val Asp Glu Ala Leu Arg
1 5
<210> 5033
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5033
Ser Val Asp Ile Trp Leu Arg
1 5
<210> 5034
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5034
Ser Val Glu Thr Ile Lys
1 5
<210> 5035
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5035
Ser Val Glu Thr Leu Lys
1 5
<210> 5036
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5036
Ser Val Phe Leu His Ala Arg
1 5
<210> 5037
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5037
Ser Val Gly Phe His Leu Pro Ser Arg
1 5
<210> 5038
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5038
Ser Val Gly Ile Leu Ser Pro Ser Tyr Thr Leu Leu Tyr Arg Tyr Met
1 5 10 15
His Phe Leu Glu Asn Gln Val Arg
20
<210> 5039
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5039
Ser Val His Glu Leu Glu Lys
1 5
<210> 5040
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5040
Ser Val His Lys Val Glu Pro Ile Thr Lys
1 5 10
<210> 5041
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5041
Ser Val His Asn Gly Ala Pro Ala Pro Val Ser Gly Glu Lys
1 5 10
<210> 5042
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5042
Ser Val Ile Pro Ser Asp Gly Pro Ser Val Ala Cys Val Lys
1 5 10
<210> 5043
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5043
Ser Val Ile Pro Ser Asp Gly Pro Ser Val Ala Cys Val Lys Lys
1 5 10 15
<210> 5044
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5044
Ser Val Ile Arg Pro Ala Thr Gln Gln Ala Gln Lys
1 5 10
<210> 5045
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5045
Ser Val Leu Gly Gln Leu Gly Ile Thr Lys
1 5 10
<210> 5046
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5046
Ser Val Leu Pro Ser Phe Pro Asp Asp Thr Lys
1 5 10
<210> 5047
<211> 27
<212> PRT
<213> Homo sapiens
<400> 5047
Ser Val Leu Arg Pro Ser Gln Phe Gly Gly Gln Pro Cys Thr Ala Pro
1 5 10 15
Leu Val Ala Phe Gln Pro Cys Ile Pro Ser Lys
20 25
<210> 5048
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5048
Ser Val Met Ala Pro Phe Thr Met Thr Ile Asp Ala His Thr Asn Gly
1 5 10 15
Asn Gly Lys
<210> 5049
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5049
Ser Val Asn Asp Leu Tyr Ile Gln Lys
1 5
<210> 5050
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5050
Ser Val Asn Asp Leu Tyr Ile Gln Lys Gln Phe Pro Ile Leu Leu Asp
1 5 10 15
Phe Lys
<210> 5051
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5051
Ser Val Asn Ile Leu Phe Asn Leu Thr His Arg
1 5 10
<210> 5052
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5052
Ser Val Asn Asn Val Val Val Arg
1 5
<210> 5053
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5053
Ser Val Pro Met Val Pro Pro Gly Ile Lys
1 5 10
<210> 5054
<211> 23
<212> PRT
<213> Homo sapiens
<400> 5054
Ser Val Pro Pro Ser Ala Ser His Val Ala Pro Thr Glu Thr Phe Thr
1 5 10 15
Tyr Glu Trp Thr Val Pro Lys
20
<210> 5055
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5055
Ser Val Gln Glu Ile Gln Ala Thr Phe Phe Tyr Phe Thr Pro Asn Lys
1 5 10 15
<210> 5056
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5056
Ser Val Gln Leu Thr Glu Lys
1 5
<210> 5057
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5057
Ser Val Gln Tyr Asp Asp Val Pro Glu Tyr Lys Asp Arg
1 5 10
<210> 5058
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5058
Ser Val Ser Asp Gly Ile Ala Ala Leu Asp Leu Asn Ala Val Ala Asn
1 5 10 15
Lys
<210> 5059
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5059
Ser Val Ser Leu Pro Ser Leu Asp Pro Ala Ser Ala Lys
1 5 10
<210> 5060
<211> 26
<212> PRT
<213> Homo sapiens
<400> 5060
Ser Val Ser Tyr Pro Ser Leu Leu Ser His Ile Thr Ser Ser Leu Met
1 5 10 15
Asn His Pro Val Ile Pro Met Ala Asn Lys
20 25
<210> 5061
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5061
Ser Val Thr Glu Gln Gly Ala Glu Leu Ser Asn Glu Glu Arg
1 5 10
<210> 5062
<211> 29
<212> PRT
<213> Homo sapiens
<400> 5062
Ser Val Thr Leu Phe Gly Glu Ser Ala Gly Ala Ala Ser Val Ser Leu
1 5 10 15
His Leu Leu Ser Pro Gly Ser His Ser Leu Phe Thr Arg
20 25
<210> 5063
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5063
Ser Val Thr Leu Asn Gln Arg
1 5
<210> 5064
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5064
Ser Val Thr Val Ala Glu Gly Leu Ile Glu Asp His Phe Asp Val Thr
1 5 10 15
Val Lys
<210> 5065
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5065
Ser Val Val Leu Ile Pro Leu Gly Ala Val Asp Asp Gly Glu His Ser
1 5 10 15
Gln Asn Glu Lys
20
<210> 5066
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5066
Ser Val Val Leu Met Ser His Leu Gly Arg Pro Asp Gly Val Pro Met
1 5 10 15
Pro Asp Lys
<210> 5067
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5067
Ser Val Val Met Pro Met Glu Lys
1 5
<210> 5068
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5068
Ser Trp Phe Glu Pro Leu Val Glu Asp Met Gln Arg
1 5 10
<210> 5069
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5069
Ser Trp Leu Ala Glu Leu Gln Gln Trp Leu Lys Pro Gly Leu Lys
1 5 10 15
<210> 5070
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5070
Ser Trp Asn Leu Met Lys
1 5
<210> 5071
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5071
Ser Trp Val Pro His Thr Phe Glu Ser Glu Leu Ser Asp Pro Val Glu
1 5 10 15
Leu Leu Val Ala Glu Ser
20
<210> 5072
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5072
Ser Trp Tyr Leu Glu Asp Asn Ile Asn Lys
1 5 10
<210> 5073
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5073
Ser Tyr Ala Asp Lys
1 5
<210> 5074
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5074
Ser Tyr Phe Glu Lys
1 5
<210> 5075
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5075
Ser Tyr Phe Pro Glu Ser Trp Leu Trp Glu Val His Leu Val Pro Arg
1 5 10 15
<210> 5076
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5076
Ser Tyr Ile Phe Ile Asp Glu Ala His Ile Thr Gln Ser Leu Thr Trp
1 5 10 15
Leu Ser Gln Met Gln Lys
20
<210> 5077
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5077
Ser Tyr Pro Asp Lys
1 5
<210> 5078
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5078
Ser Tyr Pro Glu Ile Leu Thr Leu Lys
1 5
<210> 5079
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5079
Ser Tyr Pro Pro Asp Leu Arg
1 5
<210> 5080
<211> 32
<212> PRT
<213> Homo sapiens
<400> 5080
Ser Tyr Gln Leu Leu Val Val Glu Asn Thr Val Glu Val Ala Gln Phe
1 5 10 15
Ile Asn Asn Asn Pro Glu Phe Leu Gln Leu Ala Glu Pro Phe Trp Lys
20 25 30
<210> 5081
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5081
Ser Tyr Gln Trp Lys
1 5
<210> 5082
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5082
Ser Tyr Ser Cys Gln Val Met His Glu Gly Ser Thr Val Glu Lys
1 5 10 15
<210> 5083
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5083
Ser Tyr Ser Cys Gln Val Thr His Glu Gly Ser Thr Val Glu Lys
1 5 10 15
<210> 5084
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5084
Ser Tyr Thr Ile His Tyr Ser Glu Gln Gly Val Glu Trp Lys Pro Tyr
1 5 10 15
Arg
<210> 5085
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5085
Ser Tyr Thr Ile Thr Gly Leu Gln Pro Gly Thr Asp Tyr Lys
1 5 10
<210> 5086
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5086
Ser Tyr Thr Ser His Thr Asn Glu Ile His Lys
1 5 10
<210> 5087
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5087
Ser Tyr Thr Ser His Thr Asn Glu Ile His Lys Gly Lys
1 5 10
<210> 5088
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5088
Ser Tyr Thr Val Ala Ile Ala Gly Tyr Ala Leu Ala Gln Met Gly Arg
1 5 10 15
<210> 5089
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5089
Ser Tyr Tyr Trp Ile Gly Ile Arg
1 5
<210> 5090
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5090
Thr Ala Ala Glu Asn Asp Phe Val Thr Leu Lys Lys
1 5 10
<210> 5091
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5091
Thr Ala Ala Glu Asn Glu Phe Val Thr Leu Lys Lys
1 5 10
<210> 5092
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5092
Thr Ala Ala Ile Ser Gly Tyr Ser Phe Lys
1 5 10
<210> 5093
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5093
Thr Ala Ala Gln Asn Leu Tyr Glu Lys
1 5
<210> 5094
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5094
Thr Ala Asp Gly Ile Val Ser His Leu Lys Lys
1 5 10
<210> 5095
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5095
Thr Ala Glu Asp Tyr Gln Ala Leu Asn Lys
1 5 10
<210> 5096
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5096
Thr Ala Glu Tyr Asp Val Ala Tyr Gly Glu Ser His Leu Phe Arg
1 5 10 15
<210> 5097
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5097
Thr Ala Phe Asp Glu Ala Ile Ala Glu Leu Asp Thr Leu Asn Glu Glu
1 5 10 15
Ser Tyr Lys
<210> 5098
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5098
Thr Ala Phe Asp Glu Ala Ile Ala Glu Leu Asp Thr Leu Ser Glu Glu
1 5 10 15
Ser Tyr Lys
<210> 5099
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5099
Thr Ala Phe Ile Ser Asp Phe Ala Val Thr Ala Asp Gly Asn Ala Phe
1 5 10 15
Ile Gly Asp Ile Lys
20
<210> 5100
<211> 23
<212> PRT
<213> Homo sapiens
<400> 5100
Thr Ala Phe Ile Ser Asp Phe Ala Val Thr Ala Asp Gly Asn Ala Phe
1 5 10 15
Ile Gly Asp Ile Lys Asp Lys
20
<210> 5101
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5101
Thr Ala Phe Gln Glu Ala Leu Asp Ala Ala Gly Asp Lys
1 5 10
<210> 5102
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5102
Thr Ala Phe Tyr Leu Ala Glu Phe Phe Val Asn Glu Ala Arg
1 5 10
<210> 5103
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5103
Thr Ala Gly Leu Val Lys
1 5
<210> 5104
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5104
Thr Ala Gly Trp Asn Ile Pro Met Gly Leu Leu Tyr Asn Lys
1 5 10
<210> 5105
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5105
Thr Ala His Ile Asp Val His Phe Leu Lys
1 5 10
<210> 5106
<211> 28
<212> PRT
<213> Homo sapiens
<400> 5106
Thr Ala Leu Leu Asp Ala Ala Gly Val Ala Ser Leu Leu Thr Thr Ala
1 5 10 15
Glu Val Val Val Thr Glu Ile Pro Lys Glu Glu Lys
20 25
<210> 5107
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5107
Thr Ala Pro Asp Thr Lys Pro Ser Pro Arg
1 5 10
<210> 5108
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5108
Thr Ala Gln Glu Gly Asp His Gly Ser His Val Tyr Thr Lys
1 5 10
<210> 5109
<211> 29
<212> PRT
<213> Homo sapiens
<400> 5109
Thr Ala Gln Glu Gly Asp His Gly Ser His Val Tyr Thr Lys Ala Leu
1 5 10 15
Leu Ala Tyr Ala Phe Ala Leu Ala Gly Asn Gln Asp Lys
20 25
<210> 5110
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5110
Thr Ala Arg Leu Lys
1 5
<210> 5111
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5111
Thr Ala Ser Asp Phe Ile Thr Lys
1 5
<210> 5112
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5112
Thr Ala Ser Thr Pro Thr Pro Asp Asp Lys
1 5 10
<210> 5113
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5113
Thr Ala Ser Thr Pro Thr Pro Asp Asp Lys Leu Phe Gln Lys
1 5 10
<210> 5114
<211> 23
<212> PRT
<213> Homo sapiens
<400> 5114
Thr Ala Thr Glu Ser Phe Ala Ser Asp Pro Ile Leu Tyr Arg Pro Val
1 5 10 15
Ala Val Ala Leu Asp Thr Lys
20
<210> 5115
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5115
Thr Ala Thr Pro Gln Gln Ala Gln Glu Val His Glu Lys
1 5 10
<210> 5116
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5116
Thr Ala Thr Ser Glu Tyr Gln Thr Phe Phe Asn Pro Arg
1 5 10
<210> 5117
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5117
Thr Cys Pro Lys Pro Asp Asp Leu Pro Phe Ser Thr Val Val Pro Leu
1 5 10 15
Lys
<210> 5118
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5118
Thr Cys Gln Val Asn Gly Arg
1 5
<210> 5119
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5119
Thr Asp Ala Gly Phe Thr Leu Arg
1 5
<210> 5120
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5120
Thr Asp Ala Ser Asp Val Lys Pro Cys
1 5
<210> 5121
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5121
Thr Asp Cys Leu Ser Leu Pro Ser Phe Glu Asn Ala Ile Pro Met Gly
1 5 10 15
Glu Lys
<210> 5122
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5122
Thr Asp Glu Gly Ile Ala Tyr Arg
1 5
<210> 5123
<211> 29
<212> PRT
<213> Homo sapiens
<400> 5123
Thr Asp Glu Leu Pro Gln Leu Val Thr Leu Pro His Pro Asn Leu His
1 5 10 15
Gly Pro Glu Ile Leu Asp Val Pro Ser Thr Val Gln Lys
20 25
<210> 5124
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5124
Thr Asp Phe Tyr Lys
1 5
<210> 5125
<211> 42
<212> PRT
<213> Homo sapiens
<400> 5125
Thr Asp Gly Glu Gly Ala Leu Ser Glu Pro Ser Ala Thr Val Thr Ile
1 5 10 15
Glu Glu Leu Ala Ala Pro Pro Pro Pro Val Leu Met His His Gly Glu
20 25 30
Ser Ser Gln Val Leu His Pro Gly Asn Lys
35 40
<210> 5126
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5126
Thr Asp Leu Phe Pro Lys
1 5
<210> 5127
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5127
Thr Asp Gln Val Ile Gln Ser Leu Ile Ala Leu Val Asn Asp Pro Gln
1 5 10 15
Pro Glu His Pro Leu Arg
20
<210> 5128
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5128
Thr Asp Arg Ile Leu Met Lys
1 5
<210> 5129
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5129
Thr Asp Thr Ser His His Asp Gln Asp His Pro Thr Phe Asn Lys
1 5 10 15
<210> 5130
<211> 29
<212> PRT
<213> Homo sapiens
<400> 5130
Thr Asp Thr Ser His His Asp Gln Asp His Pro Thr Phe Asn Lys Ile
1 5 10 15
Thr Pro Asn Leu Ala Glu Phe Ala Phe Ser Leu Tyr Arg
20 25
<210> 5131
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5131
Thr Glu Ala Leu Thr Ser Ala Lys
1 5
<210> 5132
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5132
Thr Glu Cys Ile Lys Pro Val Val Gln Glu Val Leu Thr Ile Thr Pro
1 5 10 15
Phe Gln Arg
<210> 5133
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5133
Thr Glu Asp Ser Ser Ser Phe Leu Ile Asp Lys
1 5 10
<210> 5134
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5134
Thr Glu Asp Thr Ile Phe Leu Arg
1 5
<210> 5135
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5135
Thr Glu Gly Asp Gly Val Tyr Thr Leu Asn Asp Lys
1 5 10
<210> 5136
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5136
Thr Glu Gly Asp Gly Val Tyr Thr Leu Asn Asp Lys Lys
1 5 10
<210> 5137
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5137
Thr Glu Gly Asp Gly Val Tyr Thr Leu Asn Asn Glu Lys
1 5 10
<210> 5138
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5138
Thr Glu Gly Gln Phe Val Asp Leu Thr Gly Asn Arg
1 5 10
<210> 5139
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5139
Thr Glu His Gly Ser Glu Met Leu Phe Phe Gly Asn Ala Ile Glu Gly
1 5 10 15
Lys
<210> 5140
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5140
Thr Glu His Ile Asn Ile His Gln Leu Arg
1 5 10
<210> 5141
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5141
Thr Glu His Pro Phe Thr Val Glu Glu Phe Val Leu Pro Lys
1 5 10
<210> 5142
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5142
Thr Glu His Tyr Glu Glu Gln Ile Glu Ala Phe Lys
1 5 10
<210> 5143
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5143
Thr Glu Ile Asp Lys Pro Ser Gln Met Gln Val Thr Asp Val Gln Asp
1 5 10 15
Asn Ser Ile Ser Val Lys
20
<210> 5144
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5144
Thr Glu Leu Arg Pro Gly Glu Thr Leu Asn Val Asn Phe Leu Leu Arg
1 5 10 15
<210> 5145
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5145
Thr Glu Leu Val Glu Pro Thr Glu Tyr Leu Val Val His Leu Lys
1 5 10 15
<210> 5146
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5146
Thr Glu Asn Glu Leu Leu Arg
1 5
<210> 5147
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5147
Thr Glu Asn Leu Asn Asp Asp Glu Lys
1 5
<210> 5148
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5148
Thr Glu Gln Trp Ser Thr Leu Pro Pro Glu Thr Lys
1 5 10
<210> 5149
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5149
Thr Glu Gln Trp Ser Thr Leu Pro Pro Glu Thr Lys Asp His Ala Val
1 5 10 15
Asp Leu Ile Gln Lys
20
<210> 5150
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5150
Thr Glu Arg Glu Leu Leu Glu Ser Tyr Ile Asp Gly Arg
1 5 10
<210> 5151
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5151
Thr Glu Ser Ile Ile His Arg
1 5
<210> 5152
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5152
Thr Glu Val Asn Val Leu Pro Gly Ala Lys
1 5 10
<210> 5153
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5153
Thr Glu Val Ser Ser Asn His Val Leu Ile Tyr Leu Asp Lys
1 5 10
<210> 5154
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5154
Thr Phe Ala His Tyr Ala Thr Phe Arg
1 5
<210> 5155
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5155
Thr Phe Ala Gln Ala Arg
1 5
<210> 5156
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5156
Thr Phe Ala Ser Lys
1 5
<210> 5157
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5157
Thr Phe Asp Ile Glu Glu Lys
1 5
<210> 5158
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5158
Thr Phe Asp Leu Glu Glu Lys
1 5
<210> 5159
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5159
Thr Phe Phe Phe Lys
1 5
<210> 5160
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5160
Thr Phe Gly Ser Gly Glu Ala Asp Cys Gly Leu Arg Pro Leu Phe Glu
1 5 10 15
Lys
<210> 5161
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5161
Thr Phe His Glu Ala Ser Glu Asp Cys Ile Ser Arg
1 5 10
<210> 5162
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5162
Thr Phe His Phe Asn Thr Val Glu Glu Val His Ser Arg
1 5 10
<210> 5163
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5163
Thr Phe His Ile Phe Tyr Tyr Leu Leu Ser Gly Ala Gly Glu His Leu
1 5 10 15
Lys
<210> 5164
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5164
Thr Phe Ile Ala Ile Lys Pro Asp Gly Val Gln Arg
1 5 10
<210> 5165
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5165
Thr Phe Ile Glu Asp Val Asn Lys
1 5
<210> 5166
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5166
Thr Phe Ile Ser Pro Ile Lys
1 5
<210> 5167
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5167
Thr Phe Lys Asp Leu His Phe Leu Glu Glu Leu Gln Leu Gly His Asn
1 5 10 15
Arg
<210> 5168
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5168
Thr Phe Pro Gly Phe Phe Ser Pro Met Leu Gly Glu Phe Val Ser Glu
1 5 10 15
Thr Glu Ser Arg
20
<210> 5169
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5169
Thr Phe Ser Glu Trp Leu Glu Ser Val Lys
1 5 10
<210> 5170
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5170
Thr Phe Ser His Glu Leu Ser Asp Phe Gly Leu Glu Ser Thr Ala Gly
1 5 10 15
Glu Ile Pro Val Val Ala Ile Arg
20
<210> 5171
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5171
Thr Phe Thr Leu Leu Asp Pro Lys
1 5
<210> 5172
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5172
Thr Phe Thr Pro Gln Pro Pro Gly Leu Glu Arg
1 5 10
<210> 5173
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5173
Thr Phe Thr Thr Gln Glu Thr Ile Thr Asn Ala Glu Thr Ala Lys
1 5 10 15
<210> 5174
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5174
Thr Phe Val Leu Asn Phe Ile Lys
1 5
<210> 5175
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5175
Thr Phe Val Leu Ser Ala Leu Gln Pro Ser Pro Thr His Ser Ser Ser
1 5 10 15
Asn Thr Gln Arg
20
<210> 5176
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5176
Thr Phe Val Asn Ile Thr Pro Ala Glu Val Gly Val Leu Val Gly Lys
1 5 10 15
<210> 5177
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5177
Thr Phe Tyr Glu Pro Gly Glu Glu Ile Thr Tyr Ser Cys Lys Pro Gly
1 5 10 15
Tyr Val Ser Arg
20
<210> 5178
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5178
Thr Phe Tyr Ser Cys Thr Thr Glu Gly Arg
1 5 10
<210> 5179
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5179
Thr Gly Ala Gln Glu Leu Leu Arg
1 5
<210> 5180
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5180
Thr Gly Ala Val Ser Gly His Ser Leu Lys
1 5 10
<210> 5181
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5181
Thr Gly Asp Glu Ile Thr Tyr Gln Cys Arg
1 5 10
<210> 5182
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5182
Thr Gly Asp Ile Val Glu Phe Val Cys Lys
1 5 10
<210> 5183
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5183
Thr Gly Glu Ala Val Ala Glu Lys
1 5
<210> 5184
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5184
Thr Gly Glu Ala Val Ala Glu Lys Asp Ser Glu Ile Thr Phe Ile Lys
1 5 10 15
<210> 5185
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5185
Thr Gly Glu Ser Ala Glu Phe Val Cys Lys Arg
1 5 10
<210> 5186
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5186
Thr Gly Glu Ser Val Glu Phe Val Cys Lys
1 5 10
<210> 5187
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5187
Thr Gly Glu Ser Val Glu Phe Val Cys Lys Arg
1 5 10
<210> 5188
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5188
Thr Gly His Leu Leu Ile Gln Gly Arg
1 5
<210> 5189
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5189
Thr Gly Ile Ser Pro Leu Ala Leu Ile Lys
1 5 10
<210> 5190
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5190
Thr Gly Ile Val Ser Gly Phe Gly Arg
1 5
<210> 5191
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5191
Thr Gly Lys Ala Ala Gln Val Thr Ile Gln Ser Ser Gly Thr Phe Ser
1 5 10 15
Ser Lys
<210> 5192
<211> 27
<212> PRT
<213> Homo sapiens
<400> 5192
Thr Gly Leu Asp Ser Pro Thr Gly Ile Asp Phe Ser Asp Ile Thr Ala
1 5 10 15
Asn Ser Phe Thr Val His Trp Ile Ala Pro Arg
20 25
<210> 5193
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5193
Thr Gly Leu Lys Glu Phe Leu Lys
1 5
<210> 5194
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5194
Thr Gly Leu Leu Leu Leu Ser Asp Pro Asp Lys
1 5 10
<210> 5195
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5195
Thr Gly Leu Leu Leu Leu Ser Asp Pro Asp Lys Val Thr Ile Gly Leu
1 5 10 15
Leu Phe Trp Asp Gly Arg
20
<210> 5196
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5196
Thr Gly Leu Gln Glu Val Glu Val Lys
1 5
<210> 5197
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5197
Thr Gly Pro Asn Leu His Gly Leu Phe Gly Arg
1 5 10
<210> 5198
<211> 29
<212> PRT
<213> Homo sapiens
<400> 5198
Thr Gly Ser Gly Gly Pro Gly Asn His Pro His Gly Pro Asp Ala Ser
1 5 10 15
Ala Glu Gly Leu Asn Pro Tyr Gly Leu Val Ala Pro Arg
20 25
<210> 5199
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5199
Thr Gly Thr His Gly Leu Leu Val Lys
1 5
<210> 5200
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5200
Thr Gly Thr His Gly Leu Leu Val Lys Gln Glu Asp Met Lys
1 5 10
<210> 5201
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5201
Thr Gly Thr Thr Leu Lys
1 5
<210> 5202
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5202
Thr Gly Val Ala Val Asn Lys Pro Ala Glu Phe Thr Val Asp Ala Lys
1 5 10 15
<210> 5203
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5203
Thr Gly Val Glu Leu Gly Lys Pro Thr His Phe Thr Val Asn Ala Lys
1 5 10 15
<210> 5204
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5204
Thr Gly Val Ile Thr Ser Pro Asp Phe Pro Asn Pro Tyr Pro Lys
1 5 10 15
<210> 5205
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5205
Thr Gly Tyr Tyr Phe Asp Gly Ile Ser Arg
1 5 10
<210> 5206
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5206
Thr His Ala Val Leu Val Ala Leu Lys
1 5
<210> 5207
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5207
Thr His Ala Val Leu Val Ala Leu Lys Arg
1 5 10
<210> 5208
<211> 35
<212> PRT
<213> Homo sapiens
<400> 5208
Thr His Gly Leu Leu Gly Gln Phe Phe His Pro Ile Gly Phe Glu Val
1 5 10 15
Ser Asp Ile His Pro Gly Ser Asp Pro Thr Lys Pro Asp Ala Thr Met
20 25 30
Val Val Arg
35
<210> 5209
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5209
Thr His Gly Met Leu Pro Gly Leu Glu Pro Phe Ser His Tyr Thr Leu
1 5 10 15
Asn Val Arg
<210> 5210
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5210
Thr His Ile Leu Leu Phe Leu Pro Lys
1 5
<210> 5211
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5211
Thr His Leu Ala Pro Tyr Ser Asp Glu Leu Arg
1 5 10
<210> 5212
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5212
Thr His Leu Pro Glu Val Phe Leu Ser Lys
1 5 10
<210> 5213
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5213
Thr His Met Thr His His Pro Ile Ser Asp His Glu Ala Thr Leu Arg
1 5 10 15
<210> 5214
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5214
Thr His Asn Leu Glu Pro Tyr Phe Glu Ser Phe Ile Asn Asn Leu Arg
1 5 10 15
<210> 5215
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5215
Thr His Asn Leu Glu Pro Tyr Phe Glu Ser Phe Ile Asn Asn Leu Arg
1 5 10 15
Arg
<210> 5216
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5216
Thr His Pro Gln Phe Arg
1 5
<210> 5217
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5217
Thr His Val Thr His His Pro Ile Ser Asp His Glu Ala Thr Leu Arg
1 5 10 15
<210> 5218
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5218
Thr His Val Thr His His Pro Leu Ser Asp His Glu Ala Thr Leu Arg
1 5 10 15
<210> 5219
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5219
Thr Ile Ala Pro Ala Leu Val Ser Lys
1 5
<210> 5220
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5220
Thr Ile Ala Tyr Glu Asn Lys
1 5
<210> 5221
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5221
Thr Ile Asp Asp Leu Glu Asp Lys Leu Lys
1 5 10
<210> 5222
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5222
Thr Ile Asp Asp Leu Glu Glu Lys
1 5
<210> 5223
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5223
Thr Ile Asp Asp Leu Glu Glu Thr Leu Ala Ser Ala Lys
1 5 10
<210> 5224
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5224
Thr Ile Asp Asp Leu Lys
1 5
<210> 5225
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5225
Thr Ile Glu Gln Ile Lys
1 5
<210> 5226
<211> 28
<212> PRT
<213> Homo sapiens
<400> 5226
Thr Ile Glu Ser Ile Leu Glu Pro Val Ala Gln Gln Ile Ser His Leu
1 5 10 15
Val Ile Met His Glu Glu Gly Glu Val Asp Gly Lys
20 25
<210> 5227
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5227
Thr Ile His Asp Leu His Leu Phe Ile Glu Asn Ile Asp Phe Asn Lys
1 5 10 15
<210> 5228
<211> 38
<212> PRT
<213> Homo sapiens
<400> 5228
Thr Ile His Leu Thr Met Pro Gln Leu Val Leu Gln Gly Ser Tyr Asp
1 5 10 15
Leu Gln Asp Leu Leu Ala Gln Ala Glu Leu Pro Ala Ile Leu His Thr
20 25 30
Glu Leu Asn Leu Gln Lys
35
<210> 5229
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5229
Thr Ile Ile Gln Lys
1 5
<210> 5230
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5230
Thr Ile Lys Pro Asp Val Arg
1 5
<210> 5231
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5231
Thr Ile Leu Ala Val Thr Arg Pro Phe Ile Ser Ser Lys
1 5 10
<210> 5232
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5232
Thr Ile Leu Asp Asp Leu Arg
1 5
<210> 5233
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5233
Thr Ile Leu Asp Asp Leu Arg Ala Glu Asp His Phe Ser Val Ile Asp
1 5 10 15
Phe Asn Gln Asn Ile Arg
20
<210> 5234
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5234
Thr Ile Leu Gly Thr Met Pro Ala Phe Glu Val Ser Leu Gln Ala Leu
1 5 10 15
Gln Lys
<210> 5235
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5235
Thr Ile Leu Ile Ser Ala His Gly Asn Ser Ser Arg
1 5 10
<210> 5236
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5236
Thr Ile Leu Gln Lys
1 5
<210> 5237
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5237
Thr Ile Met Val Asp Asp Ser Lys
1 5
<210> 5238
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5238
Thr Ile Asn Ile Ala Lys
1 5
<210> 5239
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5239
Thr Ile Asn Val Pro Leu Arg
1 5
<210> 5240
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5240
Thr Ile Asn Val Pro Leu Arg Arg
1 5
<210> 5241
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5241
Thr Ile Gln Gln Ile Lys
1 5
<210> 5242
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5242
Thr Ile Gln Gln Leu Lys
1 5
<210> 5243
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5243
Thr Ile Arg Tyr Pro Asp Pro Leu Ile Lys
1 5 10
<210> 5244
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5244
Thr Ile Thr Leu Glu Val Glu Pro Ser Asp Thr Ile Glu Asn Val Lys
1 5 10 15
<210> 5245
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5245
Thr Ile Thr Thr Thr Glu Ile Met Asn Lys Pro Glu Glu Thr Ala Lys
1 5 10 15
Pro Lys
<210> 5246
<211> 26
<212> PRT
<213> Homo sapiens
<400> 5246
Thr Ile Val Arg Phe Asn Arg Pro Phe Leu Met Ile Ile Val Pro Thr
1 5 10 15
Asp Thr Gln Asn Ile Phe Phe Met Ser Lys
20 25
<210> 5247
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5247
Thr Ile Val Thr Thr Leu Gln Asp Ser Ile Arg
1 5 10
<210> 5248
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5248
Thr Ile Tyr Glu Tyr His Arg
1 5
<210> 5249
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5249
Thr Ile Tyr Thr Pro Gly Ser Thr Val Leu Tyr Arg
1 5 10
<210> 5250
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5250
Thr Lys Glu Glu Tyr Gly His Ser Glu Val Val Glu Tyr Tyr Cys Asn
1 5 10 15
Pro Arg
<210> 5251
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5251
Thr Lys Phe Ala Lys
1 5
<210> 5252
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5252
Thr Lys Gly Leu Cys Val Ala Thr Pro Val Gln Leu Arg
1 5 10
<210> 5253
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5253
Thr Lys Leu Glu Glu His Leu Glu Gly Ile Val Asn Ile Phe His Gln
1 5 10 15
Tyr Ser Val Arg
20
<210> 5254
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5254
Thr Lys Asn Asp Phe Thr Trp Phe Lys
1 5
<210> 5255
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5255
Thr Lys Pro Ser Asp Glu Glu Met Leu Phe Ile Tyr Gly His Tyr Lys
1 5 10 15
<210> 5256
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5256
Thr Lys Pro Tyr Ile Gln Val Asp Ile Gly Gly Gly Gln Thr Lys
1 5 10 15
<210> 5257
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5257
Thr Lys Thr Glu Thr Ile Thr Gly Phe Gln Val Asp Ala Val Pro Ala
1 5 10 15
Asn Gly Gln Thr Pro Ile Gln Arg
20
<210> 5258
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5258
Thr Lys Val Phe Gln Leu Lys
1 5
<210> 5259
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5259
Thr Lys Tyr Glu Thr Glu Leu Asn Leu Arg
1 5 10
<210> 5260
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5260
Thr Leu Ala Asp Leu Thr Leu Leu Asp Ser Pro Ile Lys
1 5 10
<210> 5261
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5261
Thr Leu Ala Glu Ser Ala Leu Gln Leu Leu Tyr Thr Ala Lys
1 5 10
<210> 5262
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5262
Thr Leu Ala Phe Pro Leu Thr Ile Arg
1 5
<210> 5263
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5263
Thr Leu Ala Gly Ala Val Ser Asp Leu Leu Lys
1 5 10
<210> 5264
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5264
Thr Leu Ala Gln Leu Asn Pro Glu Ser Ser Leu Phe Ile Ile Ala Ser
1 5 10 15
Lys
<210> 5265
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5265
Thr Leu Asp Asp Leu Lys
1 5
<210> 5266
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5266
Thr Leu Asp Leu Ile Asn Lys
1 5
<210> 5267
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5267
Thr Leu Glu Ala Gln Leu Thr Pro Arg
1 5
<210> 5268
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5268
Thr Leu Glu Glu Glu Ala Lys
1 5
<210> 5269
<211> 23
<212> PRT
<213> Homo sapiens
<400> 5269
Thr Leu Glu Gly Pro Val Pro Leu Glu Val Ile Val Ile Asp Gln Asn
1 5 10 15
Asp Asn Arg Pro Ile Phe Arg
20
<210> 5270
<211> 23
<212> PRT
<213> Homo sapiens
<400> 5270
Thr Leu Glu Ile Pro Gly Asn Ser Asp Pro Asn Met Ile Pro Asp Gly
1 5 10 15
Asp Phe Asn Ser Tyr Val Arg
20
<210> 5271
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5271
Thr Leu Phe Gly Leu His Leu Ser Gln Lys
1 5 10
<210> 5272
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5272
Thr Leu Phe Val His Ala Arg
1 5
<210> 5273
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5273
Thr Leu His Pro Asp Leu Gly Thr Asp Lys
1 5 10
<210> 5274
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5274
Thr Leu Ile Phe Pro Pro Ser Met His Phe Phe Gln Ala Lys
1 5 10
<210> 5275
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5275
Thr Leu Lys Gln Glu Glu Glu Thr His Ile Arg
1 5 10
<210> 5276
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5276
Thr Leu Leu Ala Glu His His Ile Thr Asn Leu Gly Trp His Thr Leu
1 5 10 15
Thr Leu Pro Ser Ser Gly Leu Arg
20
<210> 5277
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5277
Thr Leu Leu Ala Val Thr Arg Pro Phe Ile Ser Ser Lys
1 5 10
<210> 5278
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5278
Thr Leu Leu Glu Ala Glu Asn Ser Arg
1 5
<210> 5279
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5279
Thr Leu Leu Glu Gly Glu Glu Ser Arg
1 5
<210> 5280
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5280
Thr Leu Leu Gly Asp Gly Pro Val Val Thr Asp Pro Lys
1 5 10
<210> 5281
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5281
Thr Leu Leu Leu Val Gly Ser Pro Thr Trp Lys
1 5 10
<210> 5282
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5282
Thr Leu Leu Pro Val Ser Lys Pro Glu Ile Arg
1 5 10
<210> 5283
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5283
Thr Leu Leu Ser Asn Leu Glu Glu Ala Lys
1 5 10
<210> 5284
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5284
Thr Leu Leu Ser Asn Leu Glu Glu Ala Lys Lys
1 5 10
<210> 5285
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5285
Thr Leu Leu Val Glu Ala Glu Gly Ile Glu Gln Glu Lys
1 5 10
<210> 5286
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5286
Thr Leu Leu Val Phe Glu Val Gln Gln Pro Phe Leu Phe Val Leu Trp
1 5 10 15
Asp Gln Gln His Lys
20
<210> 5287
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5287
Thr Leu Met Phe Gly Ser Tyr Leu Asp Asp Glu Lys
1 5 10
<210> 5288
<211> 27
<212> PRT
<213> Homo sapiens
<400> 5288
Thr Leu Met Phe Gly Ser Tyr Leu Asp Asp Glu Lys Asn Trp Gly Leu
1 5 10 15
Ser Phe Tyr Ala Asp Lys Pro Glu Thr Thr Lys
20 25
<210> 5289
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5289
Thr Leu Met Asn Leu Gly Gly Leu Ala Val Ala Arg
1 5 10
<210> 5290
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5290
Thr Leu Asn Ala His Glu His Phe Val Thr Ser Leu Asp Phe His Lys
1 5 10 15
<210> 5291
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5291
Thr Leu Asn Asp Met Arg Gln Glu Tyr Glu Gln Leu Ile Ala Lys
1 5 10 15
<210> 5292
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5292
Thr Leu Asn Ile Cys Glu Val Gly Thr Ile Arg
1 5 10
<210> 5293
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5293
Thr Leu Asn Leu Ala Lys
1 5
<210> 5294
<211> 27
<212> PRT
<213> Homo sapiens
<400> 5294
Thr Leu Asn Leu Ala Gln Asn Leu Leu Ala Gln Leu Pro Glu Glu Leu
1 5 10 15
Phe His Pro Leu Thr Ser Leu Gln Thr Leu Lys
20 25
<210> 5295
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5295
Thr Leu Asn Asn Asp Ile Met Leu Ile Lys
1 5 10
<210> 5296
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5296
Thr Leu Asn Gln Pro Asp Ser Gln Leu Gln Leu Thr Thr Gly Asn Gly
1 5 10 15
Leu Phe Leu Ser Glu Gly Leu Lys
20
<210> 5297
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5297
Thr Leu Pro Glu Cys Ser Lys Leu Pro Asn Asn Val Leu Gln Glu Lys
1 5 10 15
<210> 5298
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5298
Thr Leu Pro Arg Asn Ser Lys
1 5
<210> 5299
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5299
Thr Leu Gln Ala Leu Glu Phe His Thr Val Pro Phe Gln Leu Leu Ala
1 5 10 15
Arg
<210> 5300
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5300
Thr Leu Gln Glu Leu Lys
1 5
<210> 5301
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5301
Thr Leu Gln Glu Leu Lys Lys
1 5
<210> 5302
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5302
Thr Leu Gln Gly Ile Pro Gln Met Ile Gly Glu Val Ile Arg Lys
1 5 10 15
<210> 5303
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5303
Thr Leu Gln Gln Ile Lys
1 5
<210> 5304
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5304
Thr Leu Gln Ser Lys Pro Ser Ala Pro Pro Gln Asp Val Lys
1 5 10
<210> 5305
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5305
Thr Leu Ser Asp Val Leu Gln Tyr Val Lys
1 5 10
<210> 5306
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5306
Thr Leu Ser Gly Thr Pro Glu Glu Ser Lys Arg
1 5 10
<210> 5307
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5307
Thr Leu Ser Gly Thr Pro Glu Val His Ser Asn Lys Arg
1 5 10
<210> 5308
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5308
Thr Leu Ser His Pro Gln Gln Met Ala Leu Leu Asp Gln Thr Lys
1 5 10 15
<210> 5309
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5309
Thr Leu Ser Pro Val Leu Glu Ser Pro Arg
1 5 10
<210> 5310
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5310
Thr Leu Thr Leu Leu Ser Val Thr Arg
1 5
<210> 5311
<211> 35
<212> PRT
<213> Homo sapiens
<400> 5311
Thr Leu Thr Ser Val Ser Val Phe Val Asp His His Leu Ala Pro Ser
1 5 10 15
Phe Tyr Phe Val Ala Phe Tyr Tyr His Gly Asp His Pro Val Ala Asn
20 25 30
Ser Leu Arg
35
<210> 5312
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5312
Thr Leu Val Leu Leu Met Gly Lys
1 5
<210> 5313
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5313
Thr Leu Val Val His Glu Lys
1 5
<210> 5314
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5314
Thr Leu Tyr Glu Thr Glu Val Phe Ser Thr Asp Phe Ser Asn Ile Ser
1 5 10 15
Ala Ala Lys
<210> 5315
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5315
Thr Met Glu Gln Phe Thr Ile His Leu Thr Val Asn Pro Gln Ser Lys
1 5 10 15
<210> 5316
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5316
Thr Met Gly Tyr Gln Asp Phe Ala Asp Val Val Cys Tyr Thr Gln Lys
1 5 10 15
<210> 5317
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5317
Thr Met Lys Leu Ile Lys
1 5
<210> 5318
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5318
Thr Met Leu Leu Gln Pro Ala Gly Ser Leu Gly Ser Tyr Ser Tyr Arg
1 5 10 15
<210> 5319
<211> 23
<212> PRT
<213> Homo sapiens
<400> 5319
Thr Met Gln Ala Leu Pro Tyr Ser Thr Val Gly Asn Ser Asn Asn Tyr
1 5 10 15
Leu His Leu Ser Val Leu Arg
20
<210> 5320
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5320
Thr Met Gln Glu Asn Ser Thr Pro Arg Glu Asp
1 5 10
<210> 5321
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5321
Thr Met Ser Gly Leu Glu Cys Gln Ala Trp Asp Ser Gln Ser Pro His
1 5 10 15
Ala His Gly Tyr Ile Pro Ser Lys
20
<210> 5322
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5322
Thr Met Thr Ile His Asn Gly Met Phe Phe Ser Thr Tyr Asp Arg
1 5 10 15
<210> 5323
<211> 26
<212> PRT
<213> Homo sapiens
<400> 5323
Thr Met Thr Ile His Asn Gly Met Phe Phe Ser Thr Tyr Asp Arg Asp
1 5 10 15
Asn Asp Gly Trp Leu Thr Ser Asp Pro Arg
20 25
<210> 5324
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5324
Thr Asn Ala Glu Asn Glu Phe Val Thr Ile Lys
1 5 10
<210> 5325
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5325
Thr Asn Ala Glu Asn Glu Phe Val Thr Ile Lys Lys
1 5 10
<210> 5326
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5326
Thr Asn Glu Glu Leu Leu Arg
1 5
<210> 5327
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5327
Thr Asn Phe Asp Asn Asp Ile Ala Leu Val Arg
1 5 10
<210> 5328
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5328
Thr Asn Ile Ile Lys
1 5
<210> 5329
<211> 27
<212> PRT
<213> Homo sapiens
<400> 5329
Thr Asn Ile Ser Asp Glu Glu Ser Glu Gln Ala Thr Glu Met Leu Val
1 5 10 15
His Asn Ala Gln Asn Leu Met Gln Ser Val Lys
20 25
<210> 5330
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5330
Thr Asn Leu Glu Ser Ile Leu Ser Tyr Pro Lys
1 5 10
<210> 5331
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5331
Thr Asn Leu Leu Lys
1 5
<210> 5332
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5332
Thr Asn Leu Asn Met Pro His Ser Leu Pro Gln Arg
1 5 10
<210> 5333
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5333
Thr Asn Asn His Ile Met Lys
1 5
<210> 5334
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5334
Thr Asn Gln Val Asn Ser Gly Gly Val Leu Leu Arg
1 5 10
<210> 5335
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5335
Thr Asn Tyr Ile Gly His Lys
1 5
<210> 5336
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5336
Thr Pro Ala Leu His Phe Lys
1 5
<210> 5337
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5337
Thr Pro Glu Gly Leu Thr Leu Leu Phe Lys
1 5 10
<210> 5338
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5338
Thr Pro Glu Asn Phe Pro Cys Lys
1 5
<210> 5339
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5339
Thr Pro Glu Pro Arg Pro Ser Leu Ser His Leu Leu Ser Gln Tyr Tyr
1 5 10 15
Gly Ala Gly Val Ala Arg
20
<210> 5340
<211> 39
<212> PRT
<213> Homo sapiens
<400> 5340
Thr Pro Phe Val Thr His Pro Gly Tyr Asp Thr Gly Asn Gly Ile Gln
1 5 10 15
Leu Pro Gly Thr Ser Gly Gln Gln Pro Ser Val Gly Gln Gln Met Ile
20 25 30
Phe Glu Glu His Gly Phe Arg
35
<210> 5341
<211> 40
<212> PRT
<213> Homo sapiens
<400> 5341
Thr Pro Phe Val Thr His Pro Gly Tyr Asp Thr Gly Asn Gly Ile Gln
1 5 10 15
Leu Pro Gly Thr Ser Gly Gln Gln Pro Ser Val Gly Gln Gln Met Ile
20 25 30
Phe Glu Glu His Gly Phe Arg Arg
35 40
<210> 5342
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5342
Thr Pro Gly Ala Ala Ala Asn Leu Glu Leu Ile Phe Val Gly Pro Gln
1 5 10 15
His Ala Gly Asn Tyr Arg
20
<210> 5343
<211> 32
<212> PRT
<213> Homo sapiens
<400> 5343
Thr Pro Gly Ile Trp Leu Leu His Cys His Val Thr Asp His Ile His
1 5 10 15
Ala Gly Met Glu Thr Thr Tyr Thr Val Leu Gln Asn Glu Asp Thr Lys
20 25 30
<210> 5344
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5344
Thr Pro His Asp Leu Phe Ser Ser Gly Leu Phe Arg
1 5 10
<210> 5345
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5345
Thr Pro Ile Thr Phe Arg
1 5
<210> 5346
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5346
Thr Pro Ile Thr Val Val Lys
1 5
<210> 5347
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5347
Thr Pro Leu Val Ala Arg
1 5
<210> 5348
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5348
Thr Pro Asn Lys Ile Asp Leu Tyr Asp Val Arg
1 5 10
<210> 5349
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5349
Thr Pro Ser Ala Ala Tyr Leu Trp Val Gly Thr Gly Ala Ser Glu Ala
1 5 10 15
Glu Lys
<210> 5350
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5350
Thr Pro Trp His Val Thr Ile Lys Pro Lys
1 5 10
<210> 5351
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5351
Thr Gln Ala Tyr Gln Asp Gln Lys Pro Gly Thr Ser Gly Leu Arg
1 5 10 15
<210> 5352
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5352
Thr Gln Phe Asn Asn Asn Glu Tyr Ser Gln Asp Leu Asp Ala Tyr Asn
1 5 10 15
Thr Lys
<210> 5353
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5353
Thr Gln Phe Asn Asn Asn Glu Tyr Ser Gln Asp Leu Asp Ala Tyr Asn
1 5 10 15
Thr Lys Asp Lys
20
<210> 5354
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5354
Thr Gln Ile Asp Ser Pro Leu Asn Gly Lys
1 5 10
<210> 5355
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5355
Thr Gln Ile Leu Ser Ile Lys Lys
1 5
<210> 5356
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5356
Thr Gln Ile Leu Val Gly Val Asn Lys
1 5
<210> 5357
<211> 25
<212> PRT
<213> Homo sapiens
<400> 5357
Thr Gln Ile Leu Val Gly Val Asn Lys Asp Glu Gly Thr Ala Phe Leu
1 5 10 15
Val Tyr Gly Ala Pro Gly Phe Ser Lys
20 25
<210> 5358
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5358
Thr Gln Leu Val Ser Asn Leu Lys Lys
1 5
<210> 5359
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5359
Thr Gln Asn Leu Ala Ala Leu Leu His Ala Ile Ala Arg
1 5 10
<210> 5360
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5360
Thr Gln Pro Asn Leu Asp Asn Cys Pro Phe His Asp Gln Pro His Leu
1 5 10 15
Lys
<210> 5361
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5361
Thr Gln Ser Gly Leu Gln Ser Tyr Leu Leu Gln Phe His Gly Leu Val
1 5 10 15
Arg
<210> 5362
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5362
Thr Gln Val Ala Asp Ala Lys
1 5
<210> 5363
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5363
Thr Gln Val Asn Arg Leu Gly Arg
1 5
<210> 5364
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5364
Thr Gln Val Ser Thr Gln Ala Glu Gln Leu Arg
1 5 10
<210> 5365
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5365
Thr Gln Val Ser Thr Gln Ala Glu Gln Leu Arg Arg
1 5 10
<210> 5366
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5366
Thr Gln Trp Ile His Phe Phe Lys
1 5
<210> 5367
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5367
Thr Arg Leu Glu Gln Glu Ile Ala Thr Tyr Arg
1 5 10
<210> 5368
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5368
Thr Arg Pro Val Val Ala Ala Gly Ala Val Gly Leu Ala Gln Arg
1 5 10 15
<210> 5369
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5369
Thr Ser Ala Leu Ser Ala Lys
1 5
<210> 5370
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5370
Thr Ser Ala Pro Pro Ser Arg Pro Pro Pro Pro Arg
1 5 10
<210> 5371
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5371
Thr Ser Cys Leu Leu Phe Met Gly Arg
1 5
<210> 5372
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5372
Thr Ser Asp Phe Leu Lys
1 5
<210> 5373
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5373
Thr Ser Asp Gln Ile His Phe Phe Phe Ala Lys
1 5 10
<210> 5374
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5374
Thr Ser Asp Gln Ile His Phe Phe Phe Ala Lys Leu Asn Cys Arg
1 5 10 15
<210> 5375
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5375
Thr Ser Glu Ser Gly Glu Leu His Gly Leu Thr Thr Glu Glu Glu Phe
1 5 10 15
Val Glu Gly Ile Tyr Lys
20
<210> 5376
<211> 28
<212> PRT
<213> Homo sapiens
<400> 5376
Thr Ser Glu Ser Gly Glu Leu His Gly Leu Thr Thr Glu Glu Glu Phe
1 5 10 15
Val Glu Gly Ile Tyr Lys Val Glu Ile Asp Thr Lys
20 25
<210> 5377
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5377
Thr Ser Glu Ser Gly Leu Pro Ser Thr Arg
1 5 10
<210> 5378
<211> 26
<212> PRT
<213> Homo sapiens
<400> 5378
Thr Ser Glu Ser Gly Thr Pro Ser Ser Ser Thr Pro Gln Glu Asn Thr
1 5 10 15
Ile Ser Gly Tyr Ser Leu Leu Thr Cys Lys
20 25
<210> 5379
<211> 23
<212> PRT
<213> Homo sapiens
<400> 5379
Thr Ser Glu Thr Lys His Asp Thr Ser Leu Lys Pro Ile Ser Val Ser
1 5 10 15
Tyr Asn Pro Ala Thr Ala Lys
20
<210> 5380
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5380
Thr Ser Gly Val His Asp Gly Ser Leu His Lys
1 5 10
<210> 5381
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5381
Thr Ser Leu Glu Asp Phe Tyr Leu Asp Glu Glu Arg
1 5 10
<210> 5382
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5382
Thr Ser Leu Glu Val Ser Pro Asn Pro Glu Pro Pro Glu Lys Pro Val
1 5 10 15
Arg
<210> 5383
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5383
Thr Ser Leu Gln Val Pro Met Met His Gln Lys
1 5 10
<210> 5384
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5384
Thr Ser Leu Thr Val Val Leu Leu Arg
1 5
<210> 5385
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5385
Thr Ser Asn Phe Asn Ala Ala Ile Ser Leu Lys
1 5 10
<210> 5386
<211> 26
<212> PRT
<213> Homo sapiens
<400> 5386
Thr Ser Asn Pro Tyr Arg Val Pro Ala Asn Leu Glu Asn Val Gly Phe
1 5 10 15
Glu Val Gln Thr Ala Glu Asp Asp Leu Lys
20 25
<210> 5387
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5387
Thr Ser Pro Val Asp Glu Lys
1 5
<210> 5388
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5388
Thr Ser Gln Asp Pro Leu Met Ile Lys
1 5
<210> 5389
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5389
Thr Ser Ser Phe Ala Leu Asn Leu Pro Thr Leu Pro Glu Val Lys
1 5 10 15
<210> 5390
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5390
Thr Ser Ser Phe Ala Leu Asn Leu Pro Thr Leu Pro Glu Val Lys Phe
1 5 10 15
Pro Glu Val Asp Val Leu Thr Lys
20
<210> 5391
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5391
Thr Ser Ser Ser Phe Glu Val Arg
1 5
<210> 5392
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5392
Thr Ser Thr Ala Asp Tyr Ala Met Phe Lys
1 5 10
<210> 5393
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5393
Thr Ser Thr Pro Glu Asp Phe Ile Arg
1 5
<210> 5394
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5394
Thr Ser Thr Ser Glu Glu Val Cys Ser Phe Tyr Leu Lys
1 5 10
<210> 5395
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5395
Thr Thr Asp Val Thr Gln Thr Phe Gly Ile Glu Lys
1 5 10
<210> 5396
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5396
Thr Thr Phe Asp Pro Lys
1 5
<210> 5397
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5397
Thr Thr Phe Asp Pro Lys Lys
1 5
<210> 5398
<211> 30
<212> PRT
<213> Homo sapiens
<400> 5398
Thr Thr Gly Ile Val Met Asp Ser Gly Asp Gly Val Thr His Thr Val
1 5 10 15
Pro Ile Tyr Glu Gly Tyr Ala Leu Pro His Ala Ile Leu Arg
20 25 30
<210> 5399
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5399
Thr Thr Ile Glu Lys
1 5
<210> 5400
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5400
Thr Thr Ile Glu Lys Pro Val Trp Leu Gly Phe Leu Gly Pro Ile Ile
1 5 10 15
Lys
<210> 5401
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5401
Thr Thr Lys Pro Tyr Pro Ala Asp Ile Val Val Gln Phe Lys
1 5 10
<210> 5402
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5402
Thr Thr Leu Glu Lys
1 5
<210> 5403
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5403
Thr Thr Leu Leu Ala Gly Asp Ile Glu His Pro Arg
1 5 10
<210> 5404
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5404
Thr Thr Leu Thr Ala Phe Gly Phe Ala Ser Ala Asp Leu Ile Glu Ile
1 5 10 15
Gly Leu Glu Gly Lys
20
<210> 5405
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5405
Thr Thr Met Lys Ile Ile Pro Phe Asn Arg
1 5 10
<210> 5406
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5406
Thr Thr Asn Ile Gln Gly Ile Asn Leu Leu Phe Ser Ser Arg
1 5 10
<210> 5407
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5407
Thr Thr Asn Ile Gln Gly Ile Asn Leu Leu Phe Ser Ser Arg Arg
1 5 10 15
<210> 5408
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5408
Thr Thr Pro Lys Asp Phe Tyr Val Asp Glu Asn Thr Thr Val Arg
1 5 10 15
<210> 5409
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5409
Thr Thr Ser Gly Ile His Pro Lys
1 5
<210> 5410
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5410
Thr Thr Val Met Val Lys
1 5
<210> 5411
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5411
Thr Thr Val Met Val Lys Asn Glu Asp Ser Leu Val Phe Val Gln Thr
1 5 10 15
Asp Lys
<210> 5412
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5412
Thr Val Ala Ala Cys Asn Leu Pro Ile Val Arg
1 5 10
<210> 5413
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5413
Thr Val Ala Ala Gly Ala Leu Ala Ser Leu Ser His Leu Lys
1 5 10
<210> 5414
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5414
Thr Val Ala Ile Leu Leu Lys Asp Asp Tyr Phe Val Ser Gly Ala Gly
1 5 10 15
Leu Pro Gly Arg
20
<210> 5415
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5415
Thr Val Glu Ala Glu Ala Ala His Gly Thr Val Thr Arg
1 5 10
<210> 5416
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5416
Thr Val Glu Ser Ile Thr Asp Ile Arg
1 5
<210> 5417
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5417
Thr Val Phe Gly Thr Glu Pro Asp Met Ile Arg
1 5 10
<210> 5418
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5418
Thr Val Gly Ser Asp Thr Phe Tyr Ser Phe Lys
1 5 10
<210> 5419
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5419
Thr Val Gly Ser Asp Thr Phe Tyr Ser Phe Lys Tyr Glu Ile Lys
1 5 10 15
<210> 5420
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5420
Thr Val Ile Glu Val Asp Glu Arg
1 5
<210> 5421
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5421
Thr Val Ile Gly Pro Asp Gly His Lys
1 5
<210> 5422
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5422
Thr Val Ile Gly Pro Asp Gly His Lys Glu Val Thr Lys
1 5 10
<210> 5423
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5423
Thr Val Ile Pro Gly Arg
1 5
<210> 5424
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5424
Thr Val Ile Ser Gln Ser Leu Ser Lys
1 5
<210> 5425
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5425
Thr Val Met Val Asn Ile Glu Asn Pro Glu Gly Ile Pro Val Lys
1 5 10 15
<210> 5426
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5426
Thr Val Pro Val Pro Glu Lys
1 5
<210> 5427
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5427
Thr Val Gln Ala Val Leu Thr Val Pro Lys
1 5 10
<210> 5428
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5428
Thr Val Ser Asp Ser Ile Lys
1 5
<210> 5429
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5429
Thr Val Ser Asp Ser Ile Lys Lys
1 5
<210> 5430
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5430
Thr Val Val Leu Gln Lys
1 5
<210> 5431
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5431
Thr Val Val Thr Met Ala Ser Ala Arg
1 5
<210> 5432
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5432
Thr Val Trp Ser Ala His Ser Gly Pro Thr Arg
1 5 10
<210> 5433
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5433
Thr Trp Lys Pro Thr Leu Val Ile Leu Arg
1 5 10
<210> 5434
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5434
Thr Trp Pro Ser Ser His Asn Trp Phe Phe Ala Lys
1 5 10
<210> 5435
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5435
Thr Trp Gln Asp Cys Glu Tyr Lys
1 5
<210> 5436
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5436
Thr Trp Gln Asp Tyr Lys
1 5
<210> 5437
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5437
Thr Trp Arg Asn Asp Leu Ile Ser Ala Thr Lys
1 5 10
<210> 5438
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5438
Thr Trp Tyr Pro Glu Val Pro Lys
1 5
<210> 5439
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5439
Thr Tyr Ala Met Gly His Leu Ile Gln Arg
1 5 10
<210> 5440
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5440
Thr Tyr Cys Ser Glu Pro Glu Lys
1 5
<210> 5441
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5441
Thr Tyr Cys Ser Glu Pro Glu Lys Val Asp Lys
1 5 10
<210> 5442
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5442
Thr Tyr Glu Thr Thr Leu Glu Lys
1 5
<210> 5443
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5443
Thr Tyr Phe Gly Lys
1 5
<210> 5444
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5444
Thr Tyr Phe Pro His Phe Asp Leu Ser His Gly Ser Ala Gln Val Lys
1 5 10 15
<210> 5445
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5445
Thr Tyr Gly Ala Asp Leu Ala Ser Val Asp Phe Gln His Ala Ser Glu
1 5 10 15
Asp Ala Arg
<210> 5446
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5446
Thr Tyr Gly Val Ser Phe Phe Leu Val Lys
1 5 10
<210> 5447
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5447
Thr Tyr His Val Gly Glu Gln Trp Gln Lys
1 5 10
<210> 5448
<211> 28
<212> PRT
<213> Homo sapiens
<400> 5448
Thr Tyr Ile Tyr Asp His Gly Phe Pro Tyr Thr Asp Pro Val Gly Val
1 5 10 15
Leu Tyr Glu Asp Gly Asp Asp Thr Val Ala Thr Arg
20 25
<210> 5449
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5449
Thr Tyr Leu Phe Lys
1 5
<210> 5450
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5450
Thr Tyr Leu Pro Ala Val Asp Glu Lys
1 5
<210> 5451
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5451
Thr Tyr Met Leu Ala Phe Asp Val Asn Asp Glu Lys
1 5 10
<210> 5452
<211> 27
<212> PRT
<213> Homo sapiens
<400> 5452
Thr Tyr Met Leu Ala Phe Asp Val Asn Asp Glu Lys Asn Trp Gly Leu
1 5 10 15
Ser Val Tyr Ala Asp Lys Pro Glu Thr Thr Lys
20 25
<210> 5453
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5453
Thr Tyr Asn Val Leu Asp Met Lys
1 5
<210> 5454
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5454
Thr Tyr Gln Glu Val Ala Gln Lys
1 5
<210> 5455
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5455
Thr Tyr Ser Asp His Pro Glu Lys
1 5
<210> 5456
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5456
Thr Tyr Ser Thr Ser Phe Thr Pro Met Tyr His Ala Val Thr Lys
1 5 10 15
<210> 5457
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5457
Thr Tyr Ser Val Glu Tyr Leu Asp Ser Ser Lys
1 5 10
<210> 5458
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5458
Thr Tyr Tyr Ile Ala Ala Val Glu Val Glu Trp Asp Tyr Ser Pro Gln
1 5 10 15
Arg
<210> 5459
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5459
Thr Tyr Tyr Ile Ala Ala Val Glu Val Glu Trp Asp Tyr Ser Pro Gln
1 5 10 15
Arg Glu Trp Glu Lys
20
<210> 5460
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5460
Val Ala Ala Gly Ala Phe Gln Gly Leu Arg
1 5 10
<210> 5461
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5461
Val Ala Ala Gln Asn Ser Asp Lys
1 5
<210> 5462
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5462
Val Ala Ala Tyr Asp Lys Leu Glu Lys
1 5
<210> 5463
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5463
Val Ala Cys Glu Glu Pro Pro Phe Ile Glu Asn Gly Ala Ala Asn Leu
1 5 10 15
His Ser Lys
<210> 5464
<211> 29
<212> PRT
<213> Homo sapiens
<400> 5464
Val Ala Asp Ala Leu Thr Asn Ala Val Ala His Val Asp Asp Met Pro
1 5 10 15
Asn Ala Leu Ser Ala Leu Ser Asp Leu His Ala His Lys
20 25
<210> 5465
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5465
Val Ala Glu Gly Thr Gln Val Leu Glu Leu Pro Phe Lys
1 5 10
<210> 5466
<211> 28
<212> PRT
<213> Homo sapiens
<400> 5466
Val Ala Glu Gly Thr Gln Val Leu Glu Leu Pro Phe Lys Gly Asp Asp
1 5 10 15
Ile Thr Met Val Leu Ile Leu Pro Lys Pro Glu Lys
20 25
<210> 5467
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5467
Val Ala Glu Tyr Met Asp Trp Ile Leu Glu Lys
1 5 10
<210> 5468
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5468
Val Ala Phe Leu Thr Val Thr Leu His Gln Gly Gly Ala Thr Arg
1 5 10 15
<210> 5469
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5469
Val Ala Phe Pro Leu Glu Val Val Gln Lys
1 5 10
<210> 5470
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5470
Val Ala Gly Gly Arg Ala Ala Ala Leu Arg
1 5 10
<210> 5471
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5471
Val Ala His Glu Ile Asn His Gly Ile Gly Gln Ala Gly Lys
1 5 10
<210> 5472
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5472
Val Ala His Gln Leu Gln Ala Leu Arg
1 5
<210> 5473
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5473
Val Ala Ile Ile Ile Pro Phe Arg
1 5
<210> 5474
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5474
Val Ala Ile Leu Ile Pro Phe Arg
1 5
<210> 5475
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5475
Val Ala Ile Val Val Gly Ala Pro Arg
1 5
<210> 5476
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5476
Val Ala Leu Thr Glu Asp Arg
1 5
<210> 5477
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5477
Val Ala Leu Val Thr Phe Asn Ser Ala Ala His Asn Lys Pro Ser Leu
1 5 10 15
Ile Arg
<210> 5478
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5478
Val Ala Asn Pro Cys Val Lys
1 5
<210> 5479
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5479
Val Ala Asn Pro Ser Arg
1 5
<210> 5480
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5480
Val Ala Asn Tyr Phe Asp Trp Ile Ser Tyr His Val Gly Arg Pro Phe
1 5 10 15
Ile Ser Gln Tyr Asn Val
20
<210> 5481
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5481
Val Ala Pro Ala Pro Ala Arg Pro Ser Gly Pro Ser Lys
1 5 10
<210> 5482
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5482
Val Ala Pro Glu Glu His Pro Val Leu Leu Thr Glu Ala Pro Leu Asn
1 5 10 15
Pro Lys
<210> 5483
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5483
Val Ala Gln Leu Glu Ala Gln Cys Gln Glu Pro Cys Lys Asp Thr Val
1 5 10 15
Gln Ile His Asp Ile Thr Gly Lys
20
<210> 5484
<211> 23
<212> PRT
<213> Homo sapiens
<400> 5484
Val Ala Gln Val Ile Ile Pro Ser Thr Tyr Val Pro Gly Thr Thr Asn
1 5 10 15
His Asp Ile Ala Leu Leu Arg
20
<210> 5485
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5485
Val Ala Ser Tyr Gly Val Lys Pro Arg
1 5
<210> 5486
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5486
Val Ala Thr Thr Val Ile Ser Lys
1 5
<210> 5487
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5487
Val Ala Val Ile Val Ser Asn Asp His Ala Gly Lys
1 5 10
<210> 5488
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5488
Val Ala Val Asn Asp Ala His Leu Leu Gln Tyr Asn His Arg
1 5 10
<210> 5489
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5489
Val Ala Val Val Glu Tyr His Asp Gly Ser His Ala Tyr Ile Gly Leu
1 5 10 15
Lys
<210> 5490
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5490
Val Ala Val Val Gln Tyr Ser Gly Thr Gly Gln Gln Arg Pro Glu Arg
1 5 10 15
<210> 5491
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5491
Val Ala Trp His Tyr Asp Glu Glu Lys
1 5
<210> 5492
<211> 23
<212> PRT
<213> Homo sapiens
<400> 5492
Val Ala Trp His Tyr Asp Glu Glu Lys Ile Glu Phe Glu Trp Asn Thr
1 5 10 15
Gly Thr Asn Val Asp Thr Lys
20
<210> 5493
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5493
Val Ala Tyr Asp Leu Val Tyr Tyr Val Arg
1 5 10
<210> 5494
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5494
Val Cys Asn Arg Tyr Glu Phe Leu Asn Gly Arg
1 5 10
<210> 5495
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5495
Val Cys Pro Phe Ala Gly Ile Leu Glu Asn Gly Ala Val Arg
1 5 10
<210> 5496
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5496
Val Cys Ser Gln Tyr Ala Ala Tyr Gly Glu Lys
1 5 10
<210> 5497
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5497
Val Cys Ser Ser Pro Pro Ile His Met Lys
1 5 10
<210> 5498
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5498
Val Asp Glu Val Ile Lys
1 5
<210> 5499
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5499
Val Asp Phe Thr Leu Ser Ser Glu Arg
1 5
<210> 5500
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5500
Val Asp Phe Thr Leu Ser Ser Glu Arg Asp Phe Ala Leu Leu Ser Leu
1 5 10 15
Gln Val Pro Leu Lys
20
<210> 5501
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5501
Val Asp Gly Ala Leu Cys Met Glu Lys
1 5
<210> 5502
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5502
Val Asp Gly Ala Val Ser Ser Trp Phe Arg
1 5 10
<210> 5503
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5503
Val Asp His His Thr Asp Lys Tyr Glu Asn Asn Lys
1 5 10
<210> 5504
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5504
Val Asp Lys Asp Leu Gln Ser Leu Glu Asp Ile Leu His Gln Val Glu
1 5 10 15
Asn Lys
<210> 5505
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5505
Val Asp Lys Asp Asn Glu Asp Phe Gln Glu Ser Asn Arg
1 5 10
<210> 5506
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5506
Val Asp Leu Leu Asn Gln Glu Ile Glu Phe Leu Lys
1 5 10
<210> 5507
<211> 31
<212> PRT
<213> Homo sapiens
<400> 5507
Val Asp Leu Ser Phe Ser Pro Ala Gln Ser Pro Pro Ala Ser His Ala
1 5 10 15
His Leu Gln Val Ala Ala Ala Pro Gln Ser Leu Cys Ala Leu Arg
20 25 30
<210> 5508
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5508
Val Asp Leu Ser Phe Ser Pro Ser Gln Ser Leu Pro Ala Ser His Ala
1 5 10 15
His Leu Arg
<210> 5509
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5509
Val Asp Leu Val Asp Phe Glu Asp Asn Tyr Gln Phe Ala Lys
1 5 10
<210> 5510
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5510
Val Asp Pro Glu Ile Gln Asn Val Lys
1 5
<210> 5511
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5511
Val Asp Pro Val Asn Phe Lys
1 5
<210> 5512
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5512
Val Asp Gln Leu Lys
1 5
<210> 5513
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5513
Val Asp Arg Asp Val Ala Pro Gly Thr Leu Cys Asp Val Ala Gly Trp
1 5 10 15
Gly Ile Val Asn His Ala Gly Arg
20
<210> 5514
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5514
Val Asp Arg Pro Phe His Phe Met Ile Tyr Glu Glu Thr Ser Gly Met
1 5 10 15
Leu Leu Phe Leu Gly Arg
20
<210> 5515
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5515
Val Asp Ser His Phe Arg
1 5
<210> 5516
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5516
Val Asp Thr Val Asp Pro Pro Tyr Pro Arg
1 5 10
<210> 5517
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5517
Val Asp Val Ile Pro Val Asn Leu Pro Gly Glu His Gly Gln Arg
1 5 10 15
<210> 5518
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5518
Val Asp Val Gln Ala Gly Ala Cys Glu Gly Lys
1 5 10
<210> 5519
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5519
Val Asp Val Gln Ala Gly Ala Cys Glu Gly Lys Leu Glu Leu Ser Val
1 5 10 15
Asp Gly Ala Lys
20
<210> 5520
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5520
Val Glu Ala Asp Ile Pro Gly His Gly Gln Glu Val Leu Ile Arg
1 5 10 15
<210> 5521
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5521
Val Glu Ala Ser Ile Ser Lys
1 5
<210> 5522
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5522
Val Glu Asp Ile Pro Leu Ala Arg
1 5
<210> 5523
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5523
Val Glu Glu Glu Ala Ala Gln Lys
1 5
<210> 5524
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5524
Val Glu Glu Val Thr Lys
1 5
<210> 5525
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5525
Val Glu Phe Leu Arg Pro Ser Phe Thr Asp Gly Thr Ile Arg
1 5 10
<210> 5526
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5526
Val Glu Phe Val Leu Lys
1 5
<210> 5527
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5527
Val Glu Gly Leu Thr Phe Gln Gln Asn Ser Leu Asn Trp Met Lys
1 5 10 15
<210> 5528
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5528
Val Glu His Gly Ser Val Ala Leu Pro Ala Ile Met Arg
1 5 10
<210> 5529
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5529
Val Glu His Ser Asp Leu Ser Phe Ser Lys
1 5 10
<210> 5530
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5530
Val Glu Ile Asp Thr Lys
1 5
<210> 5531
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5531
Val Glu Ile Glu Ala Lys
1 5
<210> 5532
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5532
Val Glu Ile Phe Tyr Arg
1 5
<210> 5533
<211> 27
<212> PRT
<213> Homo sapiens
<400> 5533
Val Glu Lys Phe Asp Leu Val Pro Val Pro Thr Asn Leu Tyr Gly Asp
1 5 10 15
Phe Phe Thr Gly Asp Ala Tyr Val Ile Leu Lys
20 25
<210> 5534
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5534
Val Glu Lys Pro Thr Ala Asp Ala Glu Ala Tyr Val Phe Thr Pro Asn
1 5 10 15
Met Ile Cys Ala Gly Gly Glu Lys
20
<210> 5535
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5535
Val Glu Leu Ala Pro Leu Pro Ser Trp Gln Pro Val Gly Lys
1 5 10
<210> 5536
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5536
Val Glu Leu Glu Ala Lys
1 5
<210> 5537
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5537
Val Glu Leu Glu Asp Phe Asn Gly Asn Arg
1 5 10
<210> 5538
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5538
Val Glu Leu Glu Asp Trp Ala Gly Asn Glu Ala Tyr Ala Glu Tyr His
1 5 10 15
Phe Arg
<210> 5539
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5539
Val Glu Leu Glu Asp Trp Asn Gly Arg
1 5
<210> 5540
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5540
Val Glu Leu Glu Asp Trp Asn Gly Arg Thr Ser Thr Ala Asp Tyr Ala
1 5 10 15
Met Phe Lys
<210> 5541
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5541
Val Glu Leu Leu His Asn Pro Ala Phe Cys Ser Leu Ala Thr Thr Lys
1 5 10 15
<210> 5542
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5542
Val Glu Leu Thr Pro Leu Lys
1 5
<210> 5543
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5543
Val Glu Pro Leu Arg
1 5
<210> 5544
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5544
Val Glu Pro Leu Arg Ala Glu Leu Gln Glu Gly Ala Arg
1 5 10
<210> 5545
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5545
Val Glu Pro Leu Tyr Glu Leu Val Thr Ala Thr Asp Phe Ala Tyr Ser
1 5 10 15
Ser Thr Val Arg
20
<210> 5546
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5546
Val Glu Pro Tyr Gly Glu Asn Phe Asn Lys
1 5 10
<210> 5547
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5547
Val Glu Ser Glu Ile Lys
1 5
<210> 5548
<211> 28
<212> PRT
<213> Homo sapiens
<400> 5548
Val Glu Thr Asn Met Ala Phe Ser Pro Phe Ser Ile Ala Ser Leu Leu
1 5 10 15
Thr Gln Val Leu Leu Gly Ala Gly Glu Asn Thr Lys
20 25
<210> 5549
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5549
Val Glu Val Glu Ala Gly Lys
1 5
<210> 5550
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5550
Val Glu Val Glu Gln Lys
1 5
<210> 5551
<211> 34
<212> PRT
<213> Homo sapiens
<400> 5551
Val Glu Tyr Glu Leu Ser Glu Glu Gly Asp Glu Pro Gln Tyr Leu Asp
1 5 10 15
Leu Pro Ser Thr Ala Thr Ser Val Asn Ile Pro Asp Leu Leu Pro Gly
20 25 30
Arg Lys
<210> 5552
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5552
Val Glu Tyr Gly Phe Gln Val Lys
1 5
<210> 5553
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5553
Val Glu Tyr Gly Phe Gln Val Lys Val Leu Arg
1 5 10
<210> 5554
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5554
Val Phe Ala Lys Pro Lys
1 5
<210> 5555
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5555
Val Phe Ala Leu Asp Gln Lys
1 5
<210> 5556
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5556
Val Phe Ala Val Ser His Gly Arg
1 5
<210> 5557
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5557
Val Phe Cys Gln Pro Trp Gln Arg
1 5
<210> 5558
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5558
Val Phe Asp Glu Phe Lys Pro Leu Val Glu Glu Pro Gln Asn Leu Ile
1 5 10 15
Lys
<210> 5559
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5559
Val Phe Glu His Ile Gly Lys Lys
1 5
<210> 5560
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5560
Val Phe Glu Val His Val Arg Pro Lys
1 5
<210> 5561
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5561
Val Phe Phe Ala Ser Trp Arg
1 5
<210> 5562
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5562
Val Phe Gly Ala Leu Lys
1 5
<210> 5563
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5563
Val Phe His Leu Leu Gly Val Asp Thr Leu Val Val Thr Asn Ala Ala
1 5 10 15
Gly Gly Leu Asn Pro Lys
20
<210> 5564
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5564
Val Phe His Ser Leu Ala Lys
1 5
<210> 5565
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5565
Val Phe Ile Pro His Gly Leu Ile Met Asp Arg
1 5 10
<210> 5566
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5566
Val Phe Lys Asp Val Phe Leu Glu Met Asn Ile Pro Tyr Ser Val Val
1 5 10 15
Arg
<210> 5567
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5567
Val Phe Leu Gln Asn Leu Leu Ser Val Ser Gln Ala Arg
1 5 10
<210> 5568
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5568
Val Phe Asn Asp Met Lys
1 5
<210> 5569
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5569
Val Phe Asn Pro Arg
1 5
<210> 5570
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5570
Val Phe Pro Gly Gly Ser His Thr Tyr Val Trp Gln Val Leu Lys
1 5 10 15
<210> 5571
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5571
Val Phe Gln Phe Leu Glu Lys
1 5
<210> 5572
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5572
Val Phe Gln Leu Lys
1 5
<210> 5573
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5573
Val Phe Gln Leu Lys Arg
1 5
<210> 5574
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5574
Val Phe Gln Ser Leu Pro His Glu Asn Lys Pro Leu Thr Leu Ser Asn
1 5 10 15
Tyr Gln Thr Asn Lys
20
<210> 5575
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5575
Val Phe Gln Tyr Ile Asp Leu His Gln Asp Glu Phe Val Gln Thr Leu
1 5 10 15
Lys
<210> 5576
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5576
Val Phe Arg Glu Phe His Leu His Leu Arg
1 5 10
<210> 5577
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5577
Val Phe Ser Gly Asp Gly Lys
1 5
<210> 5578
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5578
Val Phe Ser Gly Asp Gly Lys Asp Phe Tyr Arg
1 5 10
<210> 5579
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5579
Val Phe Ser Ile Pro Phe His Lys
1 5
<210> 5580
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5580
Val Phe Ser Leu Gln Trp Gly Glu Val Lys
1 5 10
<210> 5581
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5581
Val Phe Ser Asn Gly Ala Asp Leu Ser Gly Val Thr Glu Glu Ala Pro
1 5 10 15
Leu Lys
<210> 5582
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5582
Val Phe Ser Asn Gly Ala Asp Leu Ser Gly Val Thr Glu Glu Ala Pro
1 5 10 15
Leu Lys Leu Ser Lys
20
<210> 5583
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5583
Val Phe Val Asp Gly His Gln Leu Phe Asp Phe Tyr His Arg
1 5 10
<210> 5584
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5584
Val Phe Val Phe Pro Arg
1 5
<210> 5585
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5585
Val Phe Tyr Leu Lys
1 5
<210> 5586
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5586
Val Gly Ala His Ala Gly Glu Tyr Gly Ala Glu Ala Leu Glu Arg
1 5 10 15
<210> 5587
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5587
Val Gly Ala Val Lys
1 5
<210> 5588
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5588
Val Gly Asp Ala Ile Pro Ala Val Glu Val Phe Glu Gly Glu Pro Gly
1 5 10 15
Asn Lys
<210> 5589
<211> 23
<212> PRT
<213> Homo sapiens
<400> 5589
Val Gly Asp Arg Asn Thr Glu Gln Glu Glu Gly Gly Glu Ala Val His
1 5 10 15
Glu Val Glu Val Val Ile Lys
20
<210> 5590
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5590
Val Gly Asp Thr Leu Asn Leu Asn Leu Arg
1 5 10
<210> 5591
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5591
Val Gly Asp Thr Tyr Glu Arg Pro Lys
1 5
<210> 5592
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5592
Val Gly Glu Phe Ser Gly Ala Asn Lys
1 5
<210> 5593
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5593
Val Gly Glu Val Leu Lys
1 5
<210> 5594
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5594
Val Gly Glu Tyr Ser Leu Tyr Ile Gly Arg
1 5 10
<210> 5595
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5595
Val Gly Phe Leu Lys Pro Val Gly Pro Lys Pro Ile Asn Leu Pro Lys
1 5 10 15
<210> 5596
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5596
Val Gly Phe Tyr Glu Ser Asp Val Met Gly Arg
1 5 10
<210> 5597
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5597
Val Gly Gly His Leu Arg Pro Gly Ile Val Gln Ser Gly Gly Val Val
1 5 10 15
Arg
<210> 5598
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5598
Val Gly Gly Asn Ser Lys Gly Thr Leu Lys
1 5 10
<210> 5599
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5599
Val Gly Ile Val Ala Trp His Pro Thr Ala Arg
1 5 10
<210> 5600
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5600
Val Gly Leu Phe Asn Ala Glu Leu Leu Glu Ala Leu Leu Asn Tyr Tyr
1 5 10 15
Ile Leu Asn Thr Phe Tyr Pro Lys
20
<210> 5601
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5601
Val Gly Leu Asn Glu Leu Tyr Asn Gly Gln Ile Leu Glu Thr Ile Gly
1 5 10 15
Gly Lys
<210> 5602
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5602
Val Gly Leu Ser Asp Ala Phe Val Val Val His Arg
1 5 10
<210> 5603
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5603
Val Gly Leu Ser Gly Met Ala Ile Ala Asp Val Thr Leu Leu Ser Gly
1 5 10 15
Phe His Ala Leu Arg
20
<210> 5604
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5604
Val Gly Pro Glu Ala Asp Lys
1 5
<210> 5605
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5605
Val Gly Pro Glu Ala Asp Lys Tyr Arg
1 5
<210> 5606
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5606
Val Gly Gln Leu Gln Leu Ser His Asn Leu Ser Leu Val Ile Leu Val
1 5 10 15
Pro Gln Asn Leu Lys
20
<210> 5607
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5607
Val Gly Ser Ala Lys Pro Gly Leu Gln Lys
1 5 10
<210> 5608
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5608
Val Gly Ser Ala Leu Phe Leu Ser His Asn Leu Lys
1 5 10
<210> 5609
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5609
Val Gly Ser Ala Leu Phe Leu Ser His Asn Leu Lys Phe Leu Ala Lys
1 5 10 15
<210> 5610
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5610
Val Gly Ser Ala Met Val Asn Ala Lys
1 5
<210> 5611
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5611
Val Gly Ser Pro Asn Ala Ala Val Leu Trp Leu Trp Ser Ser His Asn
1 5 10 15
Arg
<210> 5612
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5612
Val Gly Trp Glu Gln Leu Leu Thr Thr Ile Ala Arg
1 5 10
<210> 5613
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5613
Val Gly Tyr Val Ser Gly Trp Gly Gln Ser Asp Asn Phe Lys
1 5 10
<210> 5614
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5614
Val Gly Tyr Val Ser Gly Trp Gly Arg
1 5
<210> 5615
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5615
Val Gly Tyr Val Ser Gly Trp Gly Arg Asn Ala Asn Phe Lys
1 5 10
<210> 5616
<211> 27
<212> PRT
<213> Homo sapiens
<400> 5616
Val His Ala Asn Pro Leu Leu Ile Asp Val Val Thr Tyr Leu Val Ala
1 5 10 15
Leu Ile Pro Glu Pro Ser Ala Gln Gln Leu Arg
20 25
<210> 5617
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5617
Val His Ala Tyr Ile Ile Ser Ser Leu Lys
1 5 10
<210> 5618
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5618
Val His Ala Tyr Ile Ile Ser Ser Leu Lys Lys
1 5 10
<210> 5619
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5619
Val His Asp Val Asn Asp Asn Trp Pro Val Phe Thr His Arg
1 5 10
<210> 5620
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5620
Val His Gly Pro Gly Ile Gln Ser Gly Thr Thr Asn Lys Pro Asn Lys
1 5 10 15
<210> 5621
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5621
Val His Ile Gln Ser Ser Gln Thr Val Glu Ser Ser Gly Leu Tyr Thr
1 5 10 15
Leu Gln Ser Ile Leu Lys
20
<210> 5622
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5622
Val His Leu Ile Val Gln Val Ser Pro Lys
1 5 10
<210> 5623
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5623
Val His Leu Thr Pro Glu Glu Lys
1 5
<210> 5624
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5624
Val His Leu Val Gly Ile Asp Ile Phe Thr Gly Lys
1 5 10
<210> 5625
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5625
Val His Leu Val Val Phe Asn Asn Leu Gln Leu Ala Asp Gly Arg
1 5 10 15
<210> 5626
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5626
Val His Leu Val Val Phe Asn Asn Leu Gln Leu Ala Asp Gly Arg Arg
1 5 10 15
<210> 5627
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5627
Val His Pro Val Ser Thr Met Ile Lys
1 5
<210> 5628
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5628
Val His Gln Tyr Phe Asn Val Glu Leu Ile Gln Pro Gly Ala Val Lys
1 5 10 15
<210> 5629
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5629
Val His Ser Phe Pro Thr Leu Lys
1 5
<210> 5630
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5630
Val His Ser Ile Phe Pro Ala Arg
1 5
<210> 5631
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5631
Val His Ser Pro Ser Gly Ala Leu Glu Glu Cys Tyr Val Thr Glu Ile
1 5 10 15
Asp Gln Asp Lys
20
<210> 5632
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5632
Val His Val Ile Phe Asn Tyr Lys
1 5
<210> 5633
<211> 32
<212> PRT
<213> Homo sapiens
<400> 5633
Val His Val Ser Glu Glu Gly Thr Glu Pro Glu Ala Met Leu Gln Val
1 5 10 15
Leu Gly Pro Lys Pro Ala Leu Pro Ala Gly Thr Glu Asp Thr Ala Lys
20 25 30
<210> 5634
<211> 38
<212> PRT
<213> Homo sapiens
<400> 5634
Val His Val Ser Glu Glu Gly Thr Glu Pro Glu Ala Met Leu Gln Val
1 5 10 15
Leu Gly Pro Lys Pro Ala Leu Pro Ala Gly Thr Glu Asp Thr Ala Lys
20 25 30
Glu Asp Ala Ala Asn Arg
35
<210> 5635
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5635
Val His Tyr Thr Val Cys Ile Trp Arg
1 5
<210> 5636
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5636
Val Ile Ala Asp Asn Val Lys
1 5
<210> 5637
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5637
Val Ile Ala Thr Arg
1 5
<210> 5638
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5638
Val Ile Asp Ala Val Arg
1 5
<210> 5639
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5639
Val Ile Asp Ile Thr Arg
1 5
<210> 5640
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5640
Val Ile Asp Leu Thr Arg
1 5
<210> 5641
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5641
Val Ile Glu His Ile Met Glu Asp Leu Asp Thr Asn Ala Asp Lys
1 5 10 15
<210> 5642
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5642
Val Ile Glu Lys Val Gln His Ile Gln Leu Leu Gln Lys
1 5 10
<210> 5643
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5643
Val Ile Phe Gly Leu Phe Gly Lys
1 5
<210> 5644
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5644
Val Ile Phe Ile Arg
1 5
<210> 5645
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5645
Val Ile Gly Asn Met Gly Gln Thr Met Glu Gln Leu Thr Pro Glu Leu
1 5 10 15
Lys
<210> 5646
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5646
Val Ile Gly Thr Leu Lys
1 5
<210> 5647
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5647
Val Ile His Asp Asn Phe Gly Ile Val Glu Gly Leu Met Thr Thr Val
1 5 10 15
His Ala Ile Thr Ala Thr Gln Lys
20
<210> 5648
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5648
Val Ile Leu Gly Ala His Gln Glu Val Asn Leu Glu Pro His Val Gln
1 5 10 15
Glu Ile Glu Val Ser Arg
20
<210> 5649
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5649
Val Ile Leu His Leu Lys
1 5
<210> 5650
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5650
Val Ile Asn Met Ser Tyr His Pro Arg
1 5
<210> 5651
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5651
Val Ile Asn Thr Lys
1 5
<210> 5652
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5652
Val Ile Gln Tyr Leu Ala Tyr Val Ala Ser Ser His Lys
1 5 10
<210> 5653
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5653
Val Ile Ser Phe His Val Thr Arg
1 5
<210> 5654
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5654
Val Ile Val Ile Pro Val Gly Ile Gly Pro His Ala Asn Leu Lys
1 5 10 15
<210> 5655
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5655
Val Ile Val Val Ser Met Asn Tyr Arg
1 5
<210> 5656
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5656
Val Ile Tyr Thr Gln Leu Ser Lys
1 5
<210> 5657
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5657
Val Lys Ala Asp Gln Asp Ser Glu Ala Met Lys
1 5 10
<210> 5658
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5658
Val Lys Ala His Tyr Gly Gly Phe Thr Val Gln Asn Glu Ala Asn Lys
1 5 10 15
<210> 5659
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5659
Val Lys Asp Ile Ser Glu Val Val Thr Pro Arg
1 5 10
<210> 5660
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5660
Val Lys Asp Leu Ala Thr Val Tyr Val Asp Val Leu Lys
1 5 10
<210> 5661
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5661
Val Lys Glu Glu Ile Ile Glu Ala Phe Val Gln Glu Leu Arg
1 5 10
<210> 5662
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5662
Val Lys Glu Glu Val Phe Ile Gln Gln Arg
1 5 10
<210> 5663
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5663
Val Lys Glu Asn Phe Asp Lys
1 5
<210> 5664
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5664
Val Lys Ile Asp Gln Thr Val Glu Glu Leu Arg
1 5 10
<210> 5665
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5665
Val Lys Ile Glu Gln Lys
1 5
<210> 5666
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5666
Val Lys Ile Ile Phe Lys
1 5
<210> 5667
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5667
Val Lys Ile Gln Glu Lys
1 5
<210> 5668
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5668
Val Lys Leu Ile Ala Asn Thr Leu Cys Asn Ser Arg
1 5 10
<210> 5669
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5669
Val Lys Pro Leu Leu Gln Val Ser Arg
1 5
<210> 5670
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5670
Val Lys Pro Val Leu Met Asn Ser Lys
1 5
<210> 5671
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5671
Val Lys Val Glu Leu Lys
1 5
<210> 5672
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5672
Val Lys Val Glu Pro Leu Tyr Glu Leu Val Thr Ala Thr Asp Phe Ala
1 5 10 15
Tyr Ser Ser Thr Val Arg
20
<210> 5673
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5673
Val Lys Val Glu Pro Ser His Asp Ala Ser Lys
1 5 10
<210> 5674
<211> 27
<212> PRT
<213> Homo sapiens
<400> 5674
Val Lys Trp Tyr Leu Phe Gly Met Gly Asn Glu Val Asp Val His Ala
1 5 10 15
Ala Phe Phe His Gly Gln Ala Leu Thr Asn Lys
20 25
<210> 5675
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5675
Val Leu Ala Asp Lys Phe Ile Ile Pro Gly Leu Lys
1 5 10
<210> 5676
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5676
Val Leu Ala Lys Pro Gln Asn Thr Ala Glu Val Gln Lys
1 5 10
<210> 5677
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5677
Val Leu Ala Gln Leu Leu Arg
1 5
<210> 5678
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5678
Val Leu Ala Thr Arg
1 5
<210> 5679
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5679
Val Leu Asp Ala Leu Gln Ala Ile Lys
1 5
<210> 5680
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5680
Val Leu Asp Ala Val Arg
1 5
<210> 5681
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5681
Val Leu Asp Glu Leu Thr Leu Thr Lys
1 5
<210> 5682
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5682
Val Leu Asp Phe Glu His Phe Leu Pro Met Leu Gln Thr Val Ala Lys
1 5 10 15
<210> 5683
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5683
Val Leu Asp Leu Thr Arg
1 5
<210> 5684
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5684
Val Leu Glu Asp Asn Ser Ala Leu Asp Lys
1 5 10
<210> 5685
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5685
Val Leu Glu Asp Arg Pro Leu Ser Asp Lys
1 5 10
<210> 5686
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5686
Val Leu Glu Asp Ser Asp Leu Lys
1 5
<210> 5687
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5687
Val Leu Glu Glu Glu Glu Gln Arg
1 5
<210> 5688
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5688
Val Leu Glu Glu Leu His Lys
1 5
<210> 5689
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5689
Val Leu Glu Ile Gln Lys
1 5
<210> 5690
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5690
Val Leu Glu Leu Glu Lys
1 5
<210> 5691
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5691
Val Leu Glu Pro Thr Leu Lys
1 5
<210> 5692
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5692
Val Leu Phe Ala Lys
1 5
<210> 5693
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5693
Val Leu Phe Leu Arg
1 5
<210> 5694
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5694
Val Leu Phe Tyr Val Asp Ser Glu Lys
1 5
<210> 5695
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5695
Val Leu Phe Tyr Val Asp Ser Glu Lys Leu Lys
1 5 10
<210> 5696
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5696
Val Leu Gly Ala Phe Ser Asp Gly Leu Ala His Leu Asp Asn Leu Lys
1 5 10 15
<210> 5697
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5697
Val Leu Gly Gln Val Asn Lys
1 5
<210> 5698
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5698
Val Leu His Gly Asp Leu Ile Asp Phe Val Cys Lys
1 5 10
<210> 5699
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5699
Val Leu His Pro Leu Glu Gly Ala Val Val Ile Ile Phe Lys
1 5 10
<210> 5700
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5700
Val Leu His Pro Leu Glu Gly Ala Val Val Ile Ile Phe Lys Lys
1 5 10 15
<210> 5701
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5701
Val Leu Ile Ala Ala His Gly Asn Ser Leu Arg
1 5 10
<210> 5702
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5702
Val Leu Ile Phe Gln Glu Glu Asn Glu Ile Pro Ala Ser Val Phe Val
1 5 10 15
Lys
<210> 5703
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5703
Val Leu Ile Phe Ser Gln Met Val Arg
1 5
<210> 5704
<211> 31
<212> PRT
<213> Homo sapiens
<400> 5704
Val Leu Lys Asp Gln Val Asn Thr Phe Asp Asn Ile Phe Ile Ala Pro
1 5 10 15
Val Gly Ile Ser Thr Ala Met Gly Met Ile Ser Leu Gly Leu Lys
20 25 30
<210> 5705
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5705
Val Leu Leu Asp Gly Val Gln Asn Pro Arg
1 5 10
<210> 5706
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5706
Val Leu Leu Glu Ser Ile Gly Ser His Glu Glu Leu Thr Gln Asp Ser
1 5 10 15
Arg
<210> 5707
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5707
Val Leu Leu His Phe Val Gln Lys
1 5
<210> 5708
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5708
Val Leu Leu Gln Gly Lys
1 5
<210> 5709
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5709
Val Leu Leu Thr Arg Pro Gly Glu Gly Gly Thr Gly Leu Pro Gly Pro
1 5 10 15
Pro Leu Ile Thr Arg
20
<210> 5710
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5710
Val Leu Leu Tyr Met Ala Phe Met Thr Ile Met Ile Lys
1 5 10
<210> 5711
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5711
Val Leu Met Ser Val Leu Asn Asp Asn Ser Arg
1 5 10
<210> 5712
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5712
Val Leu Asn Ile Leu Glu Lys
1 5
<210> 5713
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5713
Val Leu Asn Gln Gln Leu Thr Asn His Ile Arg
1 5 10
<210> 5714
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5714
Val Leu Asn Thr Glu Ala Asn Val Val Arg
1 5 10
<210> 5715
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5715
Val Leu Asn Thr Lys
1 5
<210> 5716
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5716
Val Leu Asn Tyr Val Asp Trp Ile Lys
1 5
<210> 5717
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5717
Val Leu Asn Tyr Val Asp Trp Ile Lys Lys
1 5 10
<210> 5718
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5718
Val Leu Pro Gly His Ser Ala Gly Pro Arg
1 5 10
<210> 5719
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5719
Val Leu Pro Leu Ala Tyr Ser Gln Glu Thr Val Ser Phe Tyr Glu Asp
1 5 10 15
Leu Lys
<210> 5720
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5720
Val Leu Pro Pro Asp Leu Lys
1 5
<210> 5721
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5721
Val Leu Pro Thr His Asp Ala Ser Lys
1 5
<210> 5722
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5722
Val Leu Gln Ile Glu Lys
1 5
<210> 5723
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5723
Val Leu Gln Leu Glu Lys
1 5
<210> 5724
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5724
Val Leu Arg Glu Asn Ala Asp Ser Leu Gln Ala Ser Leu Arg Pro His
1 5 10 15
Ala Asp Glu Leu Lys
20
<210> 5725
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5725
Val Leu Arg Ser Ile Leu Glu Asn Leu Arg
1 5 10
<210> 5726
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5726
Val Leu Ser Ala Leu Gln Ala Val Gln Gly Leu Leu Val Ala Gln Gly
1 5 10 15
Arg
<210> 5727
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5727
Val Leu Ser Ala Pro Pro His Phe His Phe Gly Gln Thr Asn Arg
1 5 10 15
<210> 5728
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5728
Val Leu Ser Ile Ala Gln Ala His Ser Pro Ala Phe Ser Cys Glu Gln
1 5 10 15
Val Arg
<210> 5729
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5729
Val Leu Ser Leu Ala Gln Glu Gln Val Gly Gly Ser Pro Glu Lys
1 5 10 15
<210> 5730
<211> 42
<212> PRT
<213> Homo sapiens
<400> 5730
Val Leu Ser Leu Ala Gln Glu Gln Val Gly Gly Ser Pro Glu Lys Leu
1 5 10 15
Gln Glu Thr Ser Asn Trp Leu Leu Ser Gln Gln Gln Ala Asp Gly Ser
20 25 30
Phe Gln Asp Leu Ser Pro Val Ile His Arg
35 40
<210> 5731
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5731
Val Leu Ser Pro Ala Asp Lys
1 5
<210> 5732
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5732
Val Leu Ser Tyr Val Asp Trp Ile Lys
1 5
<210> 5733
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5733
Val Leu Thr Asp Glu Leu Lys
1 5
<210> 5734
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5734
Val Leu Thr Gly Asn Pro Arg
1 5
<210> 5735
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5735
Val Leu Thr Pro Asp Ala Phe Val Cys Arg
1 5 10
<210> 5736
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5736
Val Leu Val Asp His Phe Gly Tyr Thr Lys
1 5 10
<210> 5737
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5737
Val Leu Val Asp His Phe Gly Tyr Thr Lys Asp Asp Lys
1 5 10
<210> 5738
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5738
Val Leu Val Glu Asp Thr Lys
1 5
<210> 5739
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5739
Val Leu Val Glu Asn Glu His Arg
1 5
<210> 5740
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5740
Val Leu Val Trp His Thr Arg
1 5
<210> 5741
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5741
Val Leu Tyr Asn Leu Phe Thr Lys
1 5
<210> 5742
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5742
Val Leu Tyr Gln Ser His Leu Leu Lys Gln Ile Leu Leu Lys
1 5 10
<210> 5743
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5743
Val Met Asp Lys Tyr Thr Phe Glu Leu Ser Arg
1 5 10
<210> 5744
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5744
Val Met Leu Gly Glu Thr Asn Pro Ala Asp Ser Lys Pro Gly Thr Ile
1 5 10 15
Arg
<210> 5745
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5745
Val Met Asn His Ile Cys Ser Lys
1 5
<210> 5746
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5746
Val Met Asn Met Lys
1 5
<210> 5747
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5747
Val Met Pro Ile Cys Leu Pro Ser Lys
1 5
<210> 5748
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5748
Val Met Pro Ile Cys Leu Pro Ser Lys Asp Tyr Ala Glu Val Gly Arg
1 5 10 15
<210> 5749
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5749
Val Met Tyr Thr Gln Tyr Glu Asp Glu Ser Phe Thr Lys
1 5 10
<210> 5750
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5750
Val Asn Ala Ile Pro Phe Thr Tyr Glu Gln Leu Asp Val Leu Lys
1 5 10 15
<210> 5751
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5751
Val Asn Ala Pro Tyr Asn Lys
1 5
<210> 5752
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5752
Val Asn Asp Ala Gln Glu Tyr Arg
1 5
<210> 5753
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5753
Val Asn Asp Ala Gln Glu Tyr Arg Arg
1 5
<210> 5754
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5754
Val Asn Asp Glu Ser Thr Glu Gly Lys
1 5
<210> 5755
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5755
Val Asn Asp Glu Ser Thr Glu Gly Lys Thr Ser Tyr Arg
1 5 10
<210> 5756
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5756
Val Asn Phe Leu Ala Ser Asn Ile His Tyr Pro Ser Lys
1 5 10
<210> 5757
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5757
Val Asn Phe Leu Ala Ser Asn Ile His Tyr Pro Ser Lys Lys
1 5 10
<210> 5758
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5758
Val Asn Gly Ser Pro Val Asp Asn His Pro Phe Ala Gly Asp Val Val
1 5 10 15
Phe Pro Arg
<210> 5759
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5759
Val Asn His Leu Tyr Ser Asp Leu Ser Asp Ala Leu Val Ile Phe Gln
1 5 10 15
Leu Tyr Glu Lys
20
<210> 5760
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5760
Val Asn His Val Thr Leu Ser Gln Pro Lys
1 5 10
<210> 5761
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5761
Val Asn Ile Pro Leu Val Thr Asn Glu Glu Cys Gln Lys
1 5 10
<210> 5762
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5762
Val Asn Ile Pro Leu Val Thr Asn Glu Glu Cys Gln Lys Arg
1 5 10
<210> 5763
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5763
Val Asn Ile Val Lys
1 5
<210> 5764
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5764
Val Asn Lys Asp Asp Glu Glu Phe Ile Glu Ser Asn Lys
1 5 10
<210> 5765
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5765
Val Asn Lys Pro Pro Tyr Pro Lys
1 5
<210> 5766
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5766
Val Asn Leu Val Lys
1 5
<210> 5767
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5767
Val Asn Leu Val Lys Thr Ile His Asp Leu His Leu Phe Ile Glu Asn
1 5 10 15
Ile Asp Phe Asn Lys
20
<210> 5768
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5768
Val Asn Met Leu Lys
1 5
<210> 5769
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5769
Val Asn Pro Cys Ile Gly Gly Val Ile Leu Phe His Glu Thr Leu Tyr
1 5 10 15
Gln Lys
<210> 5770
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5770
Val Asn Pro Phe Arg Pro Gly Asp Ser Glu Pro Pro Pro Ala Pro Gly
1 5 10 15
Ala Gln Arg
<210> 5771
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5771
Val Asn Gln Asn Leu Val Tyr Glu Ser Gly Ser Leu Asn Phe Ser Lys
1 5 10 15
<210> 5772
<211> 36
<212> PRT
<213> Homo sapiens
<400> 5772
Val Asn Gln Asn Leu Val Tyr Glu Ser Gly Ser Leu Asn Phe Ser Lys
1 5 10 15
Leu Glu Ile Gln Ser Gln Val Asp Ser Gln His Val Gly His Ser Val
20 25 30
Leu Thr Ala Lys
35
<210> 5773
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5773
Val Asn Arg Asn Asn Leu Glu Leu Ser Thr Pro Leu Lys
1 5 10
<210> 5774
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5774
Val Asn Ser Phe Phe Ser Thr Phe Lys
1 5
<210> 5775
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5775
Val Asn Ser Gln Ser Leu Ser Pro Tyr Leu Phe Arg
1 5 10
<210> 5776
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5776
Val Asn Val Asp Glu Val Gly Gly Glu Ala Leu Gly Arg
1 5 10
<210> 5777
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5777
Val Asn Val Gly Ala Gly Ser His Pro Asn Lys
1 5 10
<210> 5778
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5778
Val Asn Val Gly Ala Gly Ser His Pro Asn Lys Val Lys
1 5 10
<210> 5779
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5779
Val Asn Val Gly Asp Pro Lys
1 5
<210> 5780
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5780
Val Asn Val Pro Val Ile Gly Gly His Ala Gly Lys
1 5 10
<210> 5781
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5781
Val Asn Trp Glu Glu Glu Ala Ala Ser Gly Leu Leu Thr Ser Leu Lys
1 5 10 15
<210> 5782
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5782
Val Asn Trp Glu Glu Glu Ala Ala Ser Gly Leu Leu Thr Ser Leu Lys
1 5 10 15
Asp Asn Val Pro Lys
20
<210> 5783
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5783
Val Pro Ala His Ala Val Val Val Arg
1 5
<210> 5784
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5784
Val Pro Ala Asn Leu Glu Asn Val Gly Phe Glu Val Gln Thr Ala Glu
1 5 10 15
Asp Asp Leu Lys
20
<210> 5785
<211> 25
<212> PRT
<213> Homo sapiens
<400> 5785
Val Pro Ala Asn Leu Glu Asn Val Gly Phe Glu Val Gln Thr Ala Glu
1 5 10 15
Asp Asp Leu Lys Thr Asp Phe Tyr Lys
20 25
<210> 5786
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5786
Val Pro Asp Glu Ala Pro Lys
1 5
<210> 5787
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5787
Val Pro Glu Ala Arg Pro Asn Ser Met Val Val Glu His Pro Glu Phe
1 5 10 15
Leu Lys
<210> 5788
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5788
Val Pro Glu Asn Thr Met His Ala Met Gln Gln Lys
1 5 10
<210> 5789
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5789
Val Pro Glu Val Arg
1 5
<210> 5790
<211> 28
<212> PRT
<213> Homo sapiens
<400> 5790
Val Pro Phe Asp Ala Ala Thr Leu His Thr Ser Thr Ala Met Ala Ala
1 5 10 15
Gln His Gly Met Asp Asp Asp Gly Thr Gly Gln Lys
20 25
<210> 5791
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5791
Val Pro Gly His Glu Asp Gly Val Thr Ile Ser Gly Leu Glu Pro Asp
1 5 10 15
His Lys
<210> 5792
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5792
Val Pro Gly Leu His His Thr Tyr Asp Val Leu Phe Leu Gly Thr Gly
1 5 10 15
Asp Gly Arg
<210> 5793
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5793
Val Pro Gly Leu Tyr Tyr Phe Thr Tyr His Ala Ser Ser Arg
1 5 10
<210> 5794
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5794
Val Pro Gly Thr Ser Thr Ser Ala Thr Leu Thr Gly Leu Thr Arg
1 5 10 15
<210> 5795
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5795
Val Pro His Asp Leu Asp Met Leu Leu Arg
1 5 10
<210> 5796
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5796
Val Pro Leu Ala Leu Phe Ala Leu Asn Arg
1 5 10
<210> 5797
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5797
Val Pro Leu Val Asp Arg
1 5
<210> 5798
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5798
Val Pro Met Glu Val Val Leu Leu Lys Lys
1 5 10
<210> 5799
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5799
Val Pro Met Met Lys
1 5
<210> 5800
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5800
Val Pro Met Met Leu Gln Asp Gln Glu His His Trp Tyr Leu His Asp
1 5 10 15
Arg
<210> 5801
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5801
Val Pro Met Met Asn Ser Lys
1 5
<210> 5802
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5802
Val Pro Met Met Ser Asp Pro Lys
1 5
<210> 5803
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5803
Val Pro Met Met Tyr Gly Ala Gly Lys
1 5
<210> 5804
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5804
Val Pro Pro Glu Trp Lys
1 5
<210> 5805
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5805
Val Pro Pro Pro Arg Asp Phe His Ile Asn Leu Phe Arg
1 5 10
<210> 5806
<211> 32
<212> PRT
<213> Homo sapiens
<400> 5806
Val Pro Gln Ile Pro Phe Gly Ser Ser Val His Ile Glu Pro Tyr Thr
1 5 10 15
Glu Leu Tyr His Tyr Ser Thr Ser Val Ile Thr Ser Ser Ser Thr Arg
20 25 30
<210> 5807
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5807
Val Pro Gln Thr Asp Met Thr Phe Arg
1 5
<210> 5808
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5808
Val Pro Gln Val Ser Thr Pro Thr Leu Val Glu Val Ser Arg
1 5 10
<210> 5809
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5809
Val Pro Ser His Leu Gln Ala Glu Thr Leu Val Gly Lys
1 5 10
<210> 5810
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5810
Val Pro Ser Val Tyr Pro Leu Asp Arg Leu Glu Ile Glu Leu Leu Lys
1 5 10 15
<210> 5811
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5811
Val Pro Ser Tyr Thr Leu Ile Leu Pro Ser Leu Glu Leu Pro Val Leu
1 5 10 15
His Val Pro Arg
20
<210> 5812
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5812
Val Pro Thr Ala Asp Leu Glu Asp Val Leu Pro Leu Ala Glu Asp Ile
1 5 10 15
Thr Asn Ile Leu Ser Lys
20
<210> 5813
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5813
Val Pro Val Ala Lys
1 5
<210> 5814
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5814
Val Pro Val Ala Val Gln Gly Glu Asp Thr Val Gln Ser Leu Thr Gln
1 5 10 15
Gly Asp Gly Val Ala Lys
20
<210> 5815
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5815
Val Pro Val Asp Pro Ala Thr Tyr Gly Gln Phe Tyr Gly Gly Asp Ser
1 5 10 15
Tyr Ile Ile Leu Tyr Asn Tyr Arg
20
<210> 5816
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5816
Val Pro Val Glu Arg
1 5
<210> 5817
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5817
Val Pro Val His Asp Val Thr Asp Ala Ser Lys
1 5 10
<210> 5818
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5818
Val Pro Val Lys Lys
1 5
<210> 5819
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5819
Val Pro Val Asn Lys
1 5
<210> 5820
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5820
Val Pro Val Ser Gln Pro Ile Val Lys
1 5
<210> 5821
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5821
Val Gln Ala Leu Glu Glu Ala Asn Asn Asp Leu Glu Asn Lys Ile Gln
1 5 10 15
Asp Trp Tyr Asp Lys
20
<210> 5822
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5822
Val Gln Ala Met Lys
1 5
<210> 5823
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5823
Val Gln Glu Ala His Leu Thr Glu Asp Gln Ile Phe Tyr Phe Pro Lys
1 5 10 15
<210> 5824
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5824
Val Gln Phe Glu Leu His Tyr Gln Glu Val Lys
1 5 10
<210> 5825
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5825
Val Gln Phe Glu Leu His Tyr Gln Glu Val Lys Trp Arg
1 5 10
<210> 5826
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5826
Val Gln Gly Asn Asp His Ser Ala Thr Arg
1 5 10
<210> 5827
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5827
Val Gln Gly Val Glu Phe Ser His Arg
1 5
<210> 5828
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5828
Val Gln His Ile Gln Leu Leu Gln Lys
1 5
<210> 5829
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5829
Val Gln His Ile Gln Leu Leu Gln Lys Asn Val Arg
1 5 10
<210> 5830
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5830
Val Gln His Leu Gln Asn Glu Leu Ile Arg
1 5 10
<210> 5831
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5831
Val Gln Ile Asn Asp Lys
1 5
<210> 5832
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5832
Val Gln Ile Gln Glu Ser Val Arg
1 5
<210> 5833
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5833
Val Gln Ile Tyr His Asn Pro Thr Ala Asn Ser Phe Arg
1 5 10
<210> 5834
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5834
Val Gln Leu Ser Asn Asp Phe Asp Glu Tyr Ile Met Ala Ile Glu Gln
1 5 10 15
Thr Ile Lys
<210> 5835
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5835
Val Gln Leu Tyr Asp Leu Gly Leu Gln Ile His Lys
1 5 10
<210> 5836
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5836
Val Gln Pro Tyr Leu Asp Asp Phe Gln Lys
1 5 10
<210> 5837
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5837
Val Gln Pro Tyr Leu Asp Asp Phe Gln Lys Lys
1 5 10
<210> 5838
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5838
Val Gln Gln Pro Asp Cys Arg
1 5
<210> 5839
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5839
Val Gln Ser Thr Ile Thr Ser Arg
1 5
<210> 5840
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5840
Val Gln Ser Trp Lys
1 5
<210> 5841
<211> 24
<212> PRT
<213> Homo sapiens
<400> 5841
Val Gln Ser Trp Lys Gly Ser Leu Val Gln Ala Ser Glu Ala Asn Leu
1 5 10 15
Gln Ala Ala Gln Asp Phe Val Arg
20
<210> 5842
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5842
Val Gln Thr Ala His Phe Lys
1 5
<210> 5843
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5843
Val Gln Val Leu Leu Gly Ala His Ser Leu Ser Gln Pro Glu Pro Ser
1 5 10 15
Lys
<210> 5844
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5844
Val Gln Val Leu Leu Gly Ala His Ser Leu Ser Gln Pro Glu Pro Ser
1 5 10 15
Lys Arg
<210> 5845
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5845
Val Gln Val Val Ala Gly Lys
1 5
<210> 5846
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5846
Val Gln Val Val Ala Gly Lys Lys
1 5
<210> 5847
<211> 41
<212> PRT
<213> Homo sapiens
<400> 5847
Val Arg Glu Glu Val Val Thr Val Gly Asn Ser Val Asn Glu Gly Leu
1 5 10 15
Asn Gln Pro Thr Asp Asp Ser Cys Phe Asp Pro Tyr Thr Val Ser His
20 25 30
Tyr Ala Val Gly Asp Glu Trp Glu Arg
35 40
<210> 5848
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5848
Val Arg Glu Ser Asp Glu Glu Thr Gln Ile Lys
1 5 10
<210> 5849
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5849
Val Arg Glu Tyr Tyr Phe Ala Glu Ala Gln Ile Ala Asp Phe Ser Asp
1 5 10 15
Pro Ala Phe Ile Ser Lys
20
<210> 5850
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5850
Val Arg Pro Gln Gln Leu Val Lys
1 5
<210> 5851
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5851
Val Ser Ala Leu Leu Thr Pro Ala Glu Gln Thr Gly Thr Trp Lys
1 5 10 15
<210> 5852
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5852
Val Ser Ala Gln Gln Val Gln Gly Val His Ala Arg
1 5 10
<210> 5853
<211> 20
<212> PRT
<213> Homo sapiens
<400> 5853
Val Ser Asp Ile Arg Pro Gly Ser Asp Pro Thr Lys Pro Asp Ala Thr
1 5 10 15
Leu Val Val Lys
20
<210> 5854
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5854
Val Ser Glu Ala Asp Ser Ser Asn Ala Asp Trp Val Thr Lys
1 5 10
<210> 5855
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5855
Val Ser Glu Asp Leu Arg
1 5
<210> 5856
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5856
Val Ser Glu Gly Asn His Asp Ile Ala Leu Ile Lys
1 5 10
<210> 5857
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5857
Val Ser Glu His Phe Ser Ala Met Phe Lys
1 5 10
<210> 5858
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5858
Val Ser Glu Pro Val Ser Ala Gly Arg
1 5
<210> 5859
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5859
Val Ser Phe Glu Leu Phe Ala Asp Lys
1 5
<210> 5860
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5860
Val Ser Phe Phe Cys Lys
1 5
<210> 5861
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5861
Val Ser Phe Leu Ser Ala Leu Glu Glu Tyr Thr Lys
1 5 10
<210> 5862
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5862
Val Ser Phe Asn Lys Pro Asp Ser His Gly Gly Val Pro Ile His His
1 5 10 15
Tyr Gln Val Asp Val Lys
20
<210> 5863
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5863
Val Ser Gly Leu Gly Glu Lys
1 5
<210> 5864
<211> 22
<212> PRT
<213> Homo sapiens
<400> 5864
Val Ser Gly Gln Gly Leu His Glu Gly His Thr Phe Glu Pro Ala Glu
1 5 10 15
Phe Ile Ile Asp Thr Arg
20
<210> 5865
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5865
Val Ser His Leu Leu Gly Ile Asn Val Thr Asp Phe Thr Arg
1 5 10
<210> 5866
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5866
Val Ser His Ser Glu Asp Asp Cys Leu Ala Phe Lys
1 5 10
<210> 5867
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5867
Val Ser His Val Leu Ala Ala Leu Gln Ala Gly Asn Arg
1 5 10
<210> 5868
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5868
Val Ser Ile Leu Trp Arg
1 5
<210> 5869
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5869
Val Ser Ile Thr Ser Ile Thr Val Glu Asn Val Phe Val Lys
1 5 10
<210> 5870
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5870
Val Ser Leu Ala Thr Val Asp Lys
1 5
<210> 5871
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5871
Val Ser Leu Phe Lys
1 5
<210> 5872
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5872
Val Ser Leu Phe Lys Lys
1 5
<210> 5873
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5873
Val Ser Leu Asn Ile Leu Pro Pro Glu Glu Glu Glu Glu Thr His Lys
1 5 10 15
<210> 5874
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5874
Val Ser Met Met Gln Thr Lys
1 5
<210> 5875
<211> 25
<212> PRT
<213> Homo sapiens
<400> 5875
Val Ser Asn Gly Ala Gly Thr Met Ser Val Ser Leu Val Ala Asp Glu
1 5 10 15
Asn Pro Phe Ala Gln Gly Ala Leu Lys
20 25
<210> 5876
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5876
Val Ser Asn Leu Glu Glu Arg
1 5
<210> 5877
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5877
Val Ser Asn Gln Thr Leu Ser Leu Phe Phe Thr Val Leu Gln Asp Val
1 5 10 15
Pro Val Arg
<210> 5878
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5878
Val Ser Pro Ala Ala Pro Glu Arg
1 5
<210> 5879
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5879
Val Ser Pro His Ser Gly Val Val Ala Leu Thr Lys Pro Val Pro Glu
1 5 10 15
Pro Arg
<210> 5880
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5880
Val Ser Pro Leu Thr Phe Gly Arg
1 5
<210> 5881
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5881
Val Ser Gln Glu Gly Leu Lys
1 5
<210> 5882
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5882
Val Ser Gln Met Ala Gln Tyr Phe Glu Pro Leu Thr Leu Ala Ala Val
1 5 10 15
Gly Ala Ala Ser Lys
20
<210> 5883
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5883
Val Ser Arg Pro Thr Lys
1 5
<210> 5884
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5884
Val Ser Ser Asp Asn Val Ala Asp Leu His Glu Lys
1 5 10
<210> 5885
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5885
Val Ser Ser Phe Glu Glu Lys
1 5
<210> 5886
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5886
Val Ser Ser Phe Arg
1 5
<210> 5887
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5887
Val Ser Ser Phe Tyr Ala Lys
1 5
<210> 5888
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5888
Val Ser Ser Val Glu Glu Cys Gln Lys
1 5
<210> 5889
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5889
Val Ser Thr Ala Phe Val Tyr Thr Lys
1 5
<210> 5890
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5890
Val Ser Thr Ala Phe Val Tyr Thr Lys Asn Pro Asn Gly Tyr Ser Phe
1 5 10 15
Ser Ile Pro Val Lys
20
<210> 5891
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5891
Val Ser Val Phe Val Asp Trp Ile His Lys
1 5 10
<210> 5892
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5892
Val Ser Val Phe Val Asp Trp Ile His Lys Val Met Arg
1 5 10
<210> 5893
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5893
Val Ser Val Gly Gly Glu Lys
1 5
<210> 5894
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5894
Val Ser Val Gly Gly Glu Lys Arg
1 5
<210> 5895
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5895
Val Ser Val His Pro Asp Tyr Arg
1 5
<210> 5896
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5896
Val Ser Val Asn Glu Arg
1 5
<210> 5897
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5897
Val Ser Val Gln Leu Glu Ala Ser Pro Ala Phe Leu Ala Val Pro Val
1 5 10 15
Glu Lys
<210> 5898
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5898
Val Ser Val Ser Gln Thr Ser Lys
1 5
<210> 5899
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5899
Val Ser Tyr Val Gly Leu Val Thr Val Arg
1 5 10
<210> 5900
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5900
Val Thr Ala Ala Pro Gln Ser Val Cys Ala Leu Arg
1 5 10
<210> 5901
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5901
Val Thr Ala Phe Leu Lys
1 5
<210> 5902
<211> 26
<212> PRT
<213> Homo sapiens
<400> 5902
Val Thr Ala Ser Asp Pro Leu Asp Thr Leu Gly Ser Glu Gly Ala Leu
1 5 10 15
Ser Pro Gly Gly Val Ala Ser Leu Leu Arg
20 25
<210> 5903
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5903
Val Thr Ala Trp Lys
1 5
<210> 5904
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5904
Val Thr Cys Thr Asn Ala Glu Leu Val Lys
1 5 10
<210> 5905
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5905
Val Thr Glu Glu Asn Lys Glu Leu Ala Asn Glu Leu Arg
1 5 10
<210> 5906
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5906
Val Thr Glu Gly Gly Glu Pro Tyr Arg
1 5
<210> 5907
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5907
Val Thr Phe Glu Leu Thr Tyr Glu Glu Leu Leu Lys
1 5 10
<210> 5908
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5908
Val Thr Phe Glu Leu Thr Tyr Glu Glu Leu Leu Lys Arg
1 5 10
<210> 5909
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5909
Val Thr Phe His Asn Lys
1 5
<210> 5910
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5910
Val Thr Phe His Asn Lys Gly Ala Tyr Pro Leu Ser Ile Glu Pro Ile
1 5 10 15
Gly Val Arg
<210> 5911
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5911
Val Thr Phe Lys Ala Asn Arg Pro Phe Leu Val Phe Ile Arg
1 5 10
<210> 5912
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5912
Val Thr Phe Gln Leu Thr Tyr Glu Glu Val Leu Lys
1 5 10
<210> 5913
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5913
Val Thr Phe Gln Leu Thr Tyr Glu Glu Val Leu Lys Arg
1 5 10
<210> 5914
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5914
Val Thr Gly Glu Gly Cys Val Tyr Leu Gln Thr Ser Leu Lys
1 5 10
<210> 5915
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5915
Val Thr Gly Glu Ser His Ile Gly Gly Val Leu Leu Lys
1 5 10
<210> 5916
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5916
Val Thr Gly Val Asp Thr Asp Pro His Phe Ile Ile His Val Pro Gln
1 5 10 15
Lys
<210> 5917
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5917
Val Thr Gly Val Val Leu Phe Arg
1 5
<210> 5918
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5918
Val Thr Gly Trp Gly Asn Leu Lys
1 5
<210> 5919
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5919
Val Thr Gly Trp Gly Asn Leu Lys Glu Thr Trp Thr Ala Asn Val Gly
1 5 10 15
Lys
<210> 5920
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5920
Val Thr His Thr Val Asn Lys Gly Asp Thr Ala Val Leu Ser Ala Arg
1 5 10 15
<210> 5921
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5921
Val Thr Ile Gly Leu Leu Phe Trp Asp Gly Arg
1 5 10
<210> 5922
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5922
Val Thr Ile Gly Leu Leu Phe Trp Asp Gly Arg Gly Glu Gly Leu Arg
1 5 10 15
<210> 5923
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5923
Val Thr Ile Lys Pro Ala Pro Glu Thr Glu Lys
1 5 10
<210> 5924
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5924
Val Thr Ile Leu Gly His Val Gln Arg
1 5
<210> 5925
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5925
Val Thr Ile Met Trp Thr Pro Pro Glu Ser Ala Val Thr Gly Tyr Arg
1 5 10 15
<210> 5926
<211> 31
<212> PRT
<213> Homo sapiens
<400> 5926
Val Thr Ile Met Trp Thr Pro Pro Glu Ser Ala Val Thr Gly Tyr Arg
1 5 10 15
Val Asp Val Ile Pro Val Asn Leu Pro Gly Glu His Gly Gln Arg
20 25 30
<210> 5927
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5927
Val Thr Ile Ser Val Asp Lys
1 5
<210> 5928
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5928
Val Thr Ile Thr Cys Arg
1 5
<210> 5929
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5929
Val Thr Leu Glu Glu Arg
1 5
<210> 5930
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5930
Val Thr Leu Arg Pro Tyr Leu Thr Pro Asn Asp Arg
1 5 10
<210> 5931
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5931
Val Thr Leu Thr Ser Glu Glu Glu Ala Arg
1 5 10
<210> 5932
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5932
Val Thr Met Gln Asn Leu Asn Asp Arg
1 5
<210> 5933
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5933
Val Thr Asn Pro Lys
1 5
<210> 5934
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5934
Val Thr Pro Asn Leu Met Gly His Leu Cys Gly Asn Gln Arg
1 5 10
<210> 5935
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5935
Val Thr Pro Pro Glu Gly Tyr Glu Val Val Thr Val Phe Pro Lys
1 5 10 15
<210> 5936
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5936
Val Thr Gln Ala Ile Gln Ser Phe Cys Leu Glu Lys
1 5 10
<210> 5937
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5937
Val Thr Gln Glu Phe His Met Lys
1 5
<210> 5938
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5938
Val Thr Ser Asp His Ile Asn Phe Asp Pro Val Tyr Lys
1 5 10
<210> 5939
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5939
Val Thr Ser Gly Ser Thr Thr Thr Thr Arg
1 5 10
<210> 5940
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5940
Val Thr Ser Gly Ser Thr Thr Thr Thr Arg Arg
1 5 10
<210> 5941
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5941
Val Thr Ser Ile Gln Asp Trp Val Gln Lys
1 5 10
<210> 5942
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5942
Val Thr Ser Ile Gln His Trp Val Gln Lys
1 5 10
<210> 5943
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5943
Val Thr Ser Val Leu His Lys
1 5
<210> 5944
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5944
Val Thr Thr His Pro Leu Ala Lys
1 5
<210> 5945
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5945
Val Thr Thr Pro Asp Thr Ser Thr Thr Gln His Asn Lys
1 5 10
<210> 5946
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5946
Val Thr Thr Ser Gln Asp Met Leu Ser Ile Met Glu Lys
1 5 10
<210> 5947
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5947
Val Thr Thr Thr Pro Lys
1 5
<210> 5948
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5948
Val Thr Thr Thr Pro Lys Asn Gly Pro Gly Pro Thr Lys
1 5 10
<210> 5949
<211> 23
<212> PRT
<213> Homo sapiens
<400> 5949
Val Thr Thr Val Ala Ser His Thr Ser Asp Ser Asp Val Pro Ser Gly
1 5 10 15
Val Thr Glu Val Val Val Lys
20
<210> 5950
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5950
Val Thr Val Phe Pro Ile Gly Ile Gly Asp Arg
1 5 10
<210> 5951
<211> 18
<212> PRT
<213> Homo sapiens
<400> 5951
Val Thr Val Phe Pro Ile Gly Ile Gly Asp Arg Tyr Asp Ala Ala Gln
1 5 10 15
Leu Arg
<210> 5952
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5952
Val Thr Val Leu Phe Ala Gly Gln His Ile Ala Lys
1 5 10
<210> 5953
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5953
Val Thr Val Leu Gly His Val Gln Arg
1 5
<210> 5954
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5954
Val Thr Val Leu Gly Gln Pro Lys
1 5
<210> 5955
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5955
Val Thr Trp Ala Pro Pro Pro Ser Ile Asp Leu Thr Asn Phe Leu Val
1 5 10 15
Arg
<210> 5956
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5956
Val Thr Tyr Asp Val Ser Arg
1 5
<210> 5957
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5957
Val Thr Tyr Thr Ser Gln Glu Asp Leu Val Glu Lys
1 5 10
<210> 5958
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5958
Val Thr Tyr Thr Ser Gln Glu Asp Leu Val Glu Lys Lys
1 5 10
<210> 5959
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5959
Val Val Ala Glu Gly Phe Asp Phe Ala Asn Gly Ile Asn Ile Ser Pro
1 5 10 15
Asp Gly Lys
<210> 5960
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5960
Val Val Ala Gly Val Ala Asn Ala Leu Ala His Lys
1 5 10
<210> 5961
<211> 14
<212> PRT
<213> Homo sapiens
<400> 5961
Val Val Ala Gly Val Ala Asn Ala Leu Ala His Lys Tyr His
1 5 10
<210> 5962
<211> 36
<212> PRT
<213> Homo sapiens
<400> 5962
Val Val Ala Gln Gly Val Gly Ile Pro Glu Asp Ser Ile Phe Thr Met
1 5 10 15
Ala Asp Arg Gly Glu Cys Val Pro Gly Glu Gln Glu Pro Glu Pro Ile
20 25 30
Leu Ile Pro Arg
35
<210> 5963
<211> 12
<212> PRT
<213> Homo sapiens
<400> 5963
Val Val Asp Leu Met Ala His Met Ala Ser Lys Glu
1 5 10
<210> 5964
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5964
Val Val Asp Pro Thr Lys Pro
1 5
<210> 5965
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5965
Val Val Asp Val Leu Asp Ser Ile Lys
1 5
<210> 5966
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5966
Val Val Glu Glu Gln Glu Ser Arg
1 5
<210> 5967
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5967
Val Val Glu Glu Ser Glu Leu Ala Arg
1 5
<210> 5968
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5968
Val Val Glu His Pro Glu Phe Leu Lys
1 5
<210> 5969
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5969
Val Val Glu Ile Lys
1 5
<210> 5970
<211> 5
<212> PRT
<213> Homo sapiens
<400> 5970
Val Val Glu Leu Lys
1 5
<210> 5971
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5971
Val Val Glu Pro Pro Glu Lys Asp Asp Gln Leu Val Val Leu Phe Pro
1 5 10 15
Val Gln Lys Pro Lys
20
<210> 5972
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5972
Val Val Glu Val Gly Ser Lys
1 5
<210> 5973
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5973
Val Val Phe Leu Asn Thr Gln Leu Cys Gln Phe Arg Pro Asp Ala Phe
1 5 10 15
Gly Gly Leu Pro Arg
20
<210> 5974
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5974
Val Val Gly Gly Cys Val Ala His Pro His Ser Trp Pro Trp Gln Val
1 5 10 15
Ser Leu Arg
<210> 5975
<211> 21
<212> PRT
<213> Homo sapiens
<400> 5975
Val Val Gly Gly Glu Asp Ala Lys Pro Gly Gln Phe Pro Trp Gln Val
1 5 10 15
Val Leu Asn Gly Lys
20
<210> 5976
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5976
Val Val Gly Gly His Pro Gly Asn Ser Pro Trp Thr Val Ser Leu Arg
1 5 10 15
<210> 5977
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5977
Val Val Gly Gly Leu Val Ala Leu Arg
1 5
<210> 5978
<211> 23
<212> PRT
<213> Homo sapiens
<400> 5978
Val Val Gly Leu Ile Gln Asp Leu Lys Pro Asn Thr Ile Met Val Leu
1 5 10 15
Val Asn Tyr Ile His Phe Lys
20
<210> 5979
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5979
Val Val Gly Ser Pro Lys
1 5
<210> 5980
<211> 6
<212> PRT
<213> Homo sapiens
<400> 5980
Val Val His Ala Ala Lys
1 5
<210> 5981
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5981
Val Val His Phe Ile Tyr Ile Ala Ile Leu Ser Gln Lys
1 5 10
<210> 5982
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5982
Val Val His Phe Ile Tyr Ile Ala Ile Leu Ser Gln Lys Phe Pro Lys
1 5 10 15
<210> 5983
<211> 13
<212> PRT
<213> Homo sapiens
<400> 5983
Val Val Leu Ala Gly Gly Val Ala Pro Ala Leu Phe Arg
1 5 10
<210> 5984
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5984
Val Val Leu Ala Tyr Glu Pro Val Trp Ala Ile Gly Thr Gly Lys
1 5 10 15
<210> 5985
<211> 9
<212> PRT
<213> Homo sapiens
<400> 5985
Val Val Leu Gly Asp Gln Asp Leu Lys
1 5
<210> 5986
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5986
Val Val Leu Gly Asp Gln Asp Leu Lys Lys
1 5 10
<210> 5987
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5987
Val Val Leu His Pro Asn Tyr His Gln Val Asp Ile Gly Leu Ile Lys
1 5 10 15
<210> 5988
<211> 16
<212> PRT
<213> Homo sapiens
<400> 5988
Val Val Leu His Pro Asn Tyr Ser Gln Val Asp Ile Gly Leu Ile Lys
1 5 10 15
<210> 5989
<211> 10
<212> PRT
<213> Homo sapiens
<400> 5989
Val Val Leu Lys Gly Asp Val Ser Leu Lys
1 5 10
<210> 5990
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5990
Val Val Leu Ser Gln Gly Ser Lys
1 5
<210> 5991
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5991
Val Val Leu Val Ala Val Asp Lys
1 5
<210> 5992
<211> 15
<212> PRT
<213> Homo sapiens
<400> 5992
Val Val Leu Val Ala Val Asp Lys Gly Val Phe Val Leu Asn Lys
1 5 10 15
<210> 5993
<211> 17
<212> PRT
<213> Homo sapiens
<400> 5993
Val Val Leu Val Ser Leu Gln Ser Gly Tyr Leu Phe Ile Gln Thr Asp
1 5 10 15
Lys
<210> 5994
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5994
Val Val Met Tyr Glu Gly Lys
1 5
<210> 5995
<211> 19
<212> PRT
<213> Homo sapiens
<400> 5995
Val Val Asn Asn Ser Pro Gln Pro Gln Asn Val Val Phe Asp Val Gln
1 5 10 15
Ile Pro Lys
<210> 5996
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5996
Val Val Asn Pro Thr Gln Lys
1 5
<210> 5997
<211> 7
<212> PRT
<213> Homo sapiens
<400> 5997
Val Val Pro Glu Gly Val Lys
1 5
<210> 5998
<211> 8
<212> PRT
<213> Homo sapiens
<400> 5998
Val Val Pro Glu Gly Val Lys Arg
1 5
<210> 5999
<211> 11
<212> PRT
<213> Homo sapiens
<400> 5999
Val Val Pro Gly Tyr Gly His Ala Val Leu Arg
1 5 10
<210> 6000
<211> 23
<212> PRT
<213> Homo sapiens
<400> 6000
Val Val Gln Gly Lys Glu Pro Ala His Leu Met Ser Leu Phe Gly Gly
1 5 10 15
Lys Pro Met Ile Ile Tyr Lys
20
<210> 6001
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6001
Val Val Gln Gly Leu His His Gly Val Ser Gln Ala Gly Arg
1 5 10
<210> 6002
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6002
Val Val Ser Gly Phe Ser Leu Lys
1 5
<210> 6003
<211> 24
<212> PRT
<213> Homo sapiens
<400> 6003
Val Val Ser Met Asp Glu Asn Phe His Pro Leu Asn Glu Leu Ile Pro
1 5 10 15
Leu Val Tyr Ile Gln Asp Pro Lys
20
<210> 6004
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6004
Val Val Ser Ser Ile Glu Gln Lys
1 5
<210> 6005
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6005
Val Val Ser Thr Asn Tyr Asn Gln His Ala Met Val Phe Phe Lys
1 5 10 15
<210> 6006
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6006
Val Val Ser Val Asp Glu Asn Phe Arg Pro Arg
1 5 10
<210> 6007
<211> 22
<212> PRT
<213> Homo sapiens
<400> 6007
Val Val Thr Phe Cys Asp Tyr Ala Tyr Asn Thr Phe Gln Val Thr Thr
1 5 10 15
Gly Gly Met Val Leu Lys
20
<210> 6008
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6008
Val Val Thr Phe Cys Gly His Thr Ser Lys
1 5 10
<210> 6009
<211> 28
<212> PRT
<213> Homo sapiens
<400> 6009
Val Val Thr Pro Leu Ser Pro Pro Thr Asn Leu His Leu Glu Ala Asn
1 5 10 15
Pro Asp Thr Gly Val Leu Thr Val Ser Trp Glu Arg
20 25
<210> 6010
<211> 23
<212> PRT
<213> Homo sapiens
<400> 6010
Val Val Thr Val Phe Ser Val Ala Asp Gly Tyr Ser Glu Asn Asn Val
1 5 10 15
Phe Tyr Gly His His Ala Lys
20
<210> 6011
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6011
Val Val Val Ala Glu Asn Phe Asp Glu Ile Val Asn Asn Glu Asn Lys
1 5 10 15
<210> 6012
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6012
Val Val Val His Pro Asp Tyr Arg
1 5
<210> 6013
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6013
Val Val Val Gln Lys
1 5
<210> 6014
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6014
Val Val Val Gln Lys Lys
1 5
<210> 6015
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6015
Val Val Val Gln Thr Glu Ser Gly Gly Arg
1 5 10
<210> 6016
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6016
Val Trp Glu Leu Ser Lys
1 5
<210> 6017
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6017
Val Trp Phe Glu Leu Thr Gln Gly Ser Ile Thr Lys Arg
1 5 10
<210> 6018
<211> 32
<212> PRT
<213> Homo sapiens
<400> 6018
Val Trp Pro Gln Gln Pro Ser Gly Glu Leu Phe Glu Ile Glu Ile Asp
1 5 10 15
Thr Leu Glu Thr Thr Cys His Val Leu Asp Pro Thr Pro Val Ala Arg
20 25 30
<210> 6019
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6019
Val Trp Ser Pro Leu Val Thr Glu Glu Gly Lys Arg
1 5 10
<210> 6020
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6020
Val Trp Val Tyr Pro Pro Glu Lys
1 5
<210> 6021
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6021
Val Trp Val Tyr Pro Pro Glu Lys Lys
1 5
<210> 6022
<211> 21
<212> PRT
<213> Homo sapiens
<400> 6022
Val Tyr Asp Tyr Tyr Glu Thr Asp Glu Phe Ala Ile Ala Glu Tyr Asn
1 5 10 15
Ala Pro Cys Ser Lys
20
<210> 6023
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6023
Val Tyr Glu Gly Glu Arg Pro Leu Thr Lys
1 5 10
<210> 6024
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6024
Val Tyr Phe Ala Gly Phe Pro Arg
1 5
<210> 6025
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6025
Val Tyr Phe Asp Leu Arg
1 5
<210> 6026
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6026
Val Tyr Phe Phe Lys
1 5
<210> 6027
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6027
Val Tyr Phe Phe Lys Gly Lys
1 5
<210> 6028
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6028
Val Tyr Lys Pro Ser Ala Gly Asn Asn Ser Leu Tyr Arg
1 5 10
<210> 6029
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6029
Val Tyr Leu Leu Tyr Arg Pro Gly His Tyr Asp Ile Leu Tyr Lys
1 5 10 15
<210> 6030
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6030
Val Tyr Leu Pro Trp Ser Arg
1 5
<210> 6031
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6031
Val Tyr Leu Ser Glu Cys Lys
1 5
<210> 6032
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6032
Val Tyr Leu Tyr Glu Gly Leu Leu Gly Arg
1 5 10
<210> 6033
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6033
Val Tyr Pro His Thr Pro Thr Ser Phe Lys
1 5 10
<210> 6034
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6034
Val Tyr Ser Ile Gly Arg
1 5
<210> 6035
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6035
Val Tyr Ser Leu Asn Asp Asp Leu Lys Pro Ala Lys
1 5 10
<210> 6036
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6036
Val Tyr Ser Leu Asn Asp Asp Leu Lys Pro Ala Lys Arg
1 5 10
<210> 6037
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6037
Val Tyr Ser Thr Ser Val Thr Gly Ser Arg
1 5 10
<210> 6038
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6038
Val Tyr Val His Leu Lys
1 5
<210> 6039
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6039
Val Tyr Val Tyr Asn Gly Lys
1 5
<210> 6040
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6040
Val Tyr Trp Thr Asn Trp His Thr Gly Thr Ile Ser Tyr Arg
1 5 10
<210> 6041
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6041
Trp Ala Asp Leu Ser Gly Ile Thr Lys
1 5
<210> 6042
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6042
Trp Ala Asn Phe Ala Lys
1 5
<210> 6043
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6043
Trp Cys Ala Val Ser Glu His Glu Ala Thr Lys
1 5 10
<210> 6044
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6044
Trp Cys Gly Thr Thr Gln Asn Tyr Asp Ala Asp Gln Lys
1 5 10
<210> 6045
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6045
Trp Cys His Asp Asn Gly Val Asn Tyr Lys
1 5 10
<210> 6046
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6046
Trp Asp Ala Gln Ile Pro His Gln His Arg
1 5 10
<210> 6047
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6047
Trp Asp Glu Glu Leu Ala Ala Phe Ala Lys
1 5 10
<210> 6048
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6048
Trp Asp Leu Gln His Pro His Gln His Pro Phe Glu Pro Gly Lys
1 5 10 15
<210> 6049
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6049
Trp Asp Pro Tyr Lys
1 5
<210> 6050
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6050
Trp Asp Pro Tyr Lys Gln Gly Phe Gly Asn Val Ala Thr Asn Thr Asp
1 5 10 15
Gly Lys
<210> 6051
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6051
Trp Asp Arg Glu Leu Ile Ser Glu Arg
1 5
<210> 6052
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6052
Trp Glu Ala Glu Pro Val Tyr Val Gln Arg
1 5 10
<210> 6053
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6053
Trp Glu Asp Pro Gly Lys
1 5
<210> 6054
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6054
Trp Glu His Gly Asp Gly Tyr Pro Phe Asp Gly Lys
1 5 10
<210> 6055
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6055
Trp Glu Leu Ala Leu Gly Arg
1 5
<210> 6056
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6056
Trp Glu Leu Cys Asp Ile Pro Arg
1 5
<210> 6057
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6057
Trp Glu Met Pro Phe Asp Pro Gln Asp Thr His Gln Ser Arg
1 5 10
<210> 6058
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6058
Trp Glu Arg Pro Phe Glu Val Lys
1 5
<210> 6059
<211> 24
<212> PRT
<213> Homo sapiens
<400> 6059
Trp Glu Arg Pro Phe Glu Val Lys Asp Thr Glu Glu Glu Asp Phe His
1 5 10 15
Val Asp Gln Val Thr Thr Val Lys
20
<210> 6060
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6060
Trp Glu Tyr Cys Lys
1 5
<210> 6061
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6061
Trp Glu Tyr Cys Asn Leu Lys
1 5
<210> 6062
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6062
Trp Glu Tyr Cys Asn Leu Lys Lys
1 5
<210> 6063
<211> 21
<212> PRT
<213> Homo sapiens
<400> 6063
Trp Phe Gly Ser Gly Ala Leu Leu Ser Ala Ser Trp Ile Leu Thr Ala
1 5 10 15
Ala His Val Leu Arg
20
<210> 6064
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6064
Trp Phe Leu Leu Glu Gln Pro Glu Ile Gln Val Ala His Phe Pro Phe
1 5 10 15
Lys
<210> 6065
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6065
Trp Phe Leu Gln His Arg Pro Gln Val Gly Tyr Ile Arg
1 5 10
<210> 6066
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6066
Trp Phe Tyr Ile Ala Ser Ala Phe Arg
1 5
<210> 6067
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6067
Trp Gly Tyr Cys Leu Glu Pro Lys
1 5
<210> 6068
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6068
Trp His Trp Ser Ser Gly Ser Leu Val Ser Tyr Lys
1 5 10
<210> 6069
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6069
Trp Ile Asp Ile Lys
1 5
<210> 6070
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6070
Trp Ile Ile Glu Lys Tyr Arg
1 5
<210> 6071
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6071
Trp Ile Ile Ser Ser Leu Thr Pro Lys
1 5
<210> 6072
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6072
Trp Ile Leu Thr Ala Ala His Thr Ile Tyr Pro Lys
1 5 10
<210> 6073
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6073
Trp Ile Leu Thr Ala Ala His Thr Leu Tyr Pro Lys
1 5 10
<210> 6074
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6074
Trp Ile Gln Tyr Lys
1 5
<210> 6075
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6075
Trp Ile Ser Asp His Glu Tyr Leu Tyr Lys
1 5 10
<210> 6076
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6076
Trp Ile Val Thr Ala Ala His Cys Val Glu Thr Gly Val Lys
1 5 10
<210> 6077
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6077
Trp Lys Glu Ala Thr Ile Pro Gly His Leu Asn Ser Tyr Thr Ile Lys
1 5 10 15
<210> 6078
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6078
Trp Lys Glu Thr Leu Phe Ser Val Met Pro Gly Leu Lys
1 5 10
<210> 6079
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6079
Trp Lys Asn Phe Pro Ser Pro Val Asp Ala Ala Phe Arg
1 5 10
<210> 6080
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6080
Trp Lys Thr Thr Phe Asp Pro Lys
1 5
<210> 6081
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6081
Trp Leu Asp Ile Lys
1 5
<210> 6082
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6082
Trp Leu Asp Leu Lys
1 5
<210> 6083
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6083
Trp Leu Asp Leu Ser His Asn Arg
1 5
<210> 6084
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6084
Trp Leu Asn Val Gln Leu Ser Pro Arg
1 5
<210> 6085
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6085
Trp Leu Pro Ser Ser Ser Pro Val Thr Gly Tyr Arg
1 5 10
<210> 6086
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6086
Trp Leu Gln Ala Lys Arg
1 5
<210> 6087
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6087
Trp Leu Gln Ala Gln Lys
1 5
<210> 6088
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6088
Trp Leu Gln Tyr Lys
1 5
<210> 6089
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6089
Trp Leu Ser Glu Glu Gln Arg
1 5
<210> 6090
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6090
Trp Leu Thr Phe Ser Leu Gly Lys
1 5
<210> 6091
<211> 19
<212> PRT
<213> Homo sapiens
<400> 6091
Trp Leu Thr Pro Phe Asp Pro Val Phe Thr Glu Val Asp Thr Phe His
1 5 10 15
Leu Asp Lys
<210> 6092
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6092
Trp Leu Val Gly Glu Met His Cys Gln Lys
1 5 10
<210> 6093
<211> 26
<212> PRT
<213> Homo sapiens
<400> 6093
Trp Met His Ser Phe Asn Phe Val Leu Ser Ala Asn Leu His Gly Gly
1 5 10 15
Ala Val Val Ala Asn Tyr Pro Tyr Asp Lys
20 25
<210> 6094
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6094
Trp Asn Phe Glu Lys
1 5
<210> 6095
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6095
Trp Asn Phe Tyr Tyr Ser Pro Gln Ser Ser Pro Asp Lys
1 5 10
<210> 6096
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6096
Trp Asn Phe Tyr Tyr Ser Pro Gln Ser Ser Pro Asp Lys Lys
1 5 10
<210> 6097
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6097
Trp Asn Asn Leu Leu Arg
1 5
<210> 6098
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6098
Trp Asn Asn Tyr Met Met Asp Trp Lys
1 5
<210> 6099
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6099
Trp Asn Thr Glu Asp Lys
1 5
<210> 6100
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6100
Trp Asn Tyr Ile Glu Gly Thr Lys
1 5
<210> 6101
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6101
Trp Pro Ala Val Phe Thr Arg
1 5
<210> 6102
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6102
Trp Pro Glu Pro Val Phe Gly Arg
1 5
<210> 6103
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6103
Trp Pro Thr Ser Gly Gln Leu Phe Leu Gly His Pro Lys
1 5 10
<210> 6104
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6104
Trp Gln Glu Glu Met Glu Leu Tyr Arg
1 5
<210> 6105
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6105
Trp Gln Ser Ile Pro Leu Cys Val Glu Lys
1 5 10
<210> 6106
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6106
Trp Arg Asp Ser Leu Glu Phe Arg
1 5
<210> 6107
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6107
Trp Arg Pro Lys Asn Ser Val Gly Arg
1 5
<210> 6108
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6108
Trp Ser Ala Gly Leu Thr Ser Ser Gln Val Asp Leu Tyr Ile Pro Lys
1 5 10 15
<210> 6109
<211> 32
<212> PRT
<213> Homo sapiens
<400> 6109
Trp Ser Gly Pro Leu Ser Leu Gln Glu Val Asp Glu Gln Pro Gln His
1 5 10 15
Pro Leu His Val Thr Tyr Ala Gly Ala Ala Val Asp Glu Leu Gly Lys
20 25 30
<210> 6110
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6110
Trp Ser His Pro Pro Ser Cys Ile Lys
1 5
<210> 6111
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6111
Trp Ser Asn Ser Lys
1 5
<210> 6112
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6112
Trp Ser Pro Glu Met Lys
1 5
<210> 6113
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6113
Trp Ser Arg Pro Gln Ala Pro Ile Thr Gly Tyr Arg
1 5 10
<210> 6114
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6114
Trp Ser Ser Thr Ser Pro His Arg Pro Arg
1 5 10
<210> 6115
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6115
Trp Ser Thr Phe Leu Asp Leu Lys
1 5
<210> 6116
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6116
Trp Ser Val Leu Pro Arg Pro Asp Leu His His Asp Val Asn Arg
1 5 10 15
<210> 6117
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6117
Trp Thr Gly Arg Pro Thr Cys Arg
1 5
<210> 6118
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6118
Trp Thr Leu Thr Ala Pro Pro Gly Tyr Arg
1 5 10
<210> 6119
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6119
Trp Thr Asn Gln Gln Lys
1 5
<210> 6120
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6120
Trp Thr Ser Phe Leu Lys
1 5
<210> 6121
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6121
Trp Val Phe Lys Glu Glu Asp Pro Ile His Leu Arg
1 5 10
<210> 6122
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6122
Trp Val Leu Thr Ala Ala His Cys Leu Leu Tyr Pro Pro Trp Asp Lys
1 5 10 15
<210> 6123
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6123
Trp Val Met Val Pro Met Met Ser Leu His His Leu Thr Ile Pro Tyr
1 5 10 15
Phe Arg
<210> 6124
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6124
Trp Trp His Thr Gly Ala Leu Tyr Arg
1 5
<210> 6125
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6125
Trp Tyr Glu Ile Glu Lys
1 5
<210> 6126
<211> 25
<212> PRT
<213> Homo sapiens
<400> 6126
Trp Tyr Leu Phe Gly Met Gly Asn Glu Val Asp Val His Ala Ala Phe
1 5 10 15
Phe His Gly Gln Ala Leu Thr Asn Lys
20 25
<210> 6127
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6127
Trp Tyr Gln Met Gly Ile Val Ser Trp Gly Glu Gly Cys Asp Arg Asp
1 5 10 15
Gly Lys
<210> 6128
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6128
Trp Tyr Ser Met Lys
1 5
<210> 6129
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6129
Trp Tyr Ser Met Lys Lys
1 5
<210> 6130
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6130
Trp Tyr Val Pro Val Lys
1 5
<210> 6131
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6131
Tyr Ala Ala Glu Leu His Leu Val His Trp Asn Pro Lys
1 5 10
<210> 6132
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6132
Tyr Ala Ala Glu Leu His Leu Val His Trp Asn Thr Lys
1 5 10
<210> 6133
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6133
Tyr Ala Ala Ser Ser Tyr Leu Ser Leu Thr Pro Glu Gln Trp Lys
1 5 10 15
<210> 6134
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6134
Tyr Ala Ala Ser Ser Tyr Leu Ser Leu Thr Pro Glu Gln Trp Lys Ser
1 5 10 15
His Arg
<210> 6135
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6135
Tyr Ala Phe Glu Leu Lys
1 5
<210> 6136
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6136
Tyr Ala Phe Glu Leu Lys Glu Lys
1 5
<210> 6137
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6137
Tyr Ala Phe Val Asn Trp Ile Asn Lys
1 5
<210> 6138
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6138
Tyr Ala Gly Asp Ile Ile Lys
1 5
<210> 6139
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6139
Tyr Ala Gly Ser Gln Val Ala Ser Thr Ser Glu Val Leu Lys
1 5 10
<210> 6140
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6140
Tyr Ala Leu Pro Leu Val Gly His Arg
1 5
<210> 6141
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6141
Tyr Ala Leu Tyr Asp Ala Thr Tyr Glu Thr Lys
1 5 10
<210> 6142
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6142
Tyr Ala Pro Ser Glu Ala Gly Leu His Glu Met Asp Ile Arg
1 5 10
<210> 6143
<211> 28
<212> PRT
<213> Homo sapiens
<400> 6143
Tyr Ala Val Asp Asp Val Gln Tyr Val Asp Glu Ile Ala Ser Val Leu
1 5 10 15
Thr Ser Gln Lys Pro Ser Val Leu Leu Thr Leu Arg
20 25
<210> 6144
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6144
Tyr Ala Val Ser Glu Ala Ala Ala His Lys
1 5 10
<210> 6145
<211> 19
<212> PRT
<213> Homo sapiens
<400> 6145
Tyr Ala Val Ser Glu Ala Ala Ala His Lys Tyr Gly Ile Asp Trp Ala
1 5 10 15
Ser Gly Arg
<210> 6146
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6146
Tyr Ala Tyr Leu Leu Gln Pro Ser Gln Phe His Gly Glu Pro Cys Asn
1 5 10 15
Phe Ser Asp Lys
20
<210> 6147
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6147
Tyr Cys Asp Arg Glu Tyr Ala Val Lys
1 5
<210> 6148
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6148
Tyr Asp Ala Ala Gln Leu Arg
1 5
<210> 6149
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6149
Tyr Asp Asp Leu Val Arg
1 5
<210> 6150
<211> 24
<212> PRT
<213> Homo sapiens
<400> 6150
Tyr Asp Lys Asn Gln Asp Val His Ser Ile Asn Leu Pro Phe Phe Glu
1 5 10 15
Thr Leu Gln Glu Tyr Phe Glu Arg
20
<210> 6151
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6151
Tyr Asp Leu Ala Phe Val Val Ala Ser Gln Ala Thr Lys
1 5 10
<210> 6152
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6152
Tyr Asp Leu Asp Phe Lys
1 5
<210> 6153
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6153
Tyr Asp Asn Ser Leu Lys
1 5
<210> 6154
<211> 19
<212> PRT
<213> Homo sapiens
<400> 6154
Tyr Asp Pro Ser Leu Lys Pro Leu Ser Val Ser Tyr Asp Gln Ala Thr
1 5 10 15
Ser Leu Arg
<210> 6155
<211> 19
<212> PRT
<213> Homo sapiens
<400> 6155
Tyr Asp Arg Leu Glu Ile Trp Asp Gly Phe Pro Asp Val Gly Pro His
1 5 10 15
Ile Gly Arg
<210> 6156
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6156
Tyr Asp Ser Thr Cys Glu Arg
1 5
<210> 6157
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6157
Tyr Asp Val Asp Thr Gln Met Trp Thr Ile Leu Lys
1 5 10
<210> 6158
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6158
Tyr Asp Val Asp Thr Gln Met Trp Thr Ile Leu Lys Asp Ser Arg
1 5 10 15
<210> 6159
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6159
Tyr Asp Val Glu Asn Cys Leu Ala Asn Lys
1 5 10
<210> 6160
<211> 29
<212> PRT
<213> Homo sapiens
<400> 6160
Tyr Asp Val Glu Asn Cys Leu Ala Asn Lys Val Asp Leu Ser Phe Ser
1 5 10 15
Pro Ser Gln Ser Leu Pro Ala Ser His Ala His Leu Arg
20 25
<210> 6161
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6161
Tyr Asp Tyr Val Glu Val Phe Asp Gly Glu Asn Glu Asn Gly His Phe
1 5 10 15
Arg
<210> 6162
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6162
Tyr Glu Ala Ser Ile Leu Thr His Asp Ser Ser Ile Arg
1 5 10
<210> 6163
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6163
Tyr Glu Asp Gly Thr Leu Ser Leu Thr Ser Thr Ser Asp Leu Gln Ser
1 5 10 15
Gly Ile Ile Lys
20
<210> 6164
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6164
Tyr Glu Glu Glu Ile Lys
1 5
<210> 6165
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6165
Tyr Glu Glu Leu Gln Ile Thr Ala Gly Arg
1 5 10
<210> 6166
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6166
Tyr Glu Phe Ile Leu Lys
1 5
<210> 6167
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6167
Tyr Glu Phe Ile Leu Lys Glu Tyr Glu Ser Tyr Ser Asp Phe Glu Arg
1 5 10 15
<210> 6168
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6168
Tyr Glu Phe Leu Asn Gly Arg
1 5
<210> 6169
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6169
Tyr Glu Gly Gly Arg Glu His Val Ala His Leu Leu Phe Leu Arg
1 5 10 15
<210> 6170
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6170
Tyr Glu Ile Phe Lys
1 5
<210> 6171
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6171
Tyr Glu Ile Asn Lys
1 5
<210> 6172
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6172
Tyr Glu Ile Thr Thr Ile His Asn Leu Phe Arg
1 5 10
<210> 6173
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6173
Tyr Glu Ile Val Val Glu Ala Arg
1 5
<210> 6174
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6174
Tyr Glu Lys Pro Asp Gly Ser Pro Val Phe Ile Ala Phe Arg
1 5 10
<210> 6175
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6175
Tyr Glu Lys Pro Gly Ser Pro Pro Arg
1 5
<210> 6176
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6176
Tyr Glu Leu Phe Lys
1 5
<210> 6177
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6177
Tyr Glu Leu Leu Tyr Leu Ala Glu Gln Phe Ala Gly Val Val Leu Tyr
1 5 10 15
Leu Lys
<210> 6178
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6178
Tyr Glu Met His Glu Leu Leu Arg
1 5
<210> 6179
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6179
Tyr Glu Met Tyr Leu Lys
1 5
<210> 6180
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6180
Tyr Glu Asn Glu Val Ala Leu Arg
1 5
<210> 6181
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6181
Tyr Glu Asn Tyr Glu Leu Thr Leu Lys
1 5
<210> 6182
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6182
Tyr Glu Pro Gln Leu Pro Asp His Trp Glu Lys
1 5 10
<210> 6183
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6183
Tyr Glu Val Gln Gly Glu Val Phe Thr Lys Pro Gln Leu Trp Pro
1 5 10 15
<210> 6184
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6184
Tyr Glu Val Ser Val Tyr Ala Leu Lys
1 5
<210> 6185
<211> 31
<212> PRT
<213> Homo sapiens
<400> 6185
Tyr Glu Val Ser Val Tyr Ala Leu Lys Asp Thr Leu Thr Ser Arg Pro
1 5 10 15
Ala Gln Gly Val Val Thr Thr Leu Glu Asn Val Ser Pro Pro Arg
20 25 30
<210> 6186
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6186
Tyr Glu Tyr Leu Glu Gly Gly Asp Arg
1 5
<210> 6187
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6187
Tyr Phe Glu Ile Thr Asp Glu Ser Pro Tyr Val His Tyr Leu Asn Thr
1 5 10 15
Phe Ser Ser Lys
20
<210> 6188
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6188
Tyr Phe Phe Thr Ser Val Ser Arg Pro Gly Arg
1 5 10
<210> 6189
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6189
Tyr Phe His His Asn Ser Asp Phe His Ile Pro Lys
1 5 10
<210> 6190
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6190
Tyr Phe His His Asn Ser Asp Phe Tyr Ile Pro Lys
1 5 10
<210> 6191
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6191
Tyr Phe His Leu Ile Asn Arg
1 5
<210> 6192
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6192
Tyr Phe Ile Asp Phe Val Ala Arg
1 5
<210> 6193
<211> 24
<212> PRT
<213> Homo sapiens
<400> 6193
Tyr Phe Lys Pro Gly Met Pro Phe Asp Leu Met Val Phe Val Thr Asn
1 5 10 15
Pro Asp Gly Ser Pro Ala Tyr Arg
20
<210> 6194
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6194
Tyr Phe Asn Tyr Lys
1 5
<210> 6195
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6195
Tyr Phe Gln Phe Gln Glu Glu Gly Lys Glu Gly Glu Asn Arg
1 5 10
<210> 6196
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6196
Tyr Phe Gln His Leu Leu Gly Lys
1 5
<210> 6197
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6197
Tyr Phe Tyr Asn Lys
1 5
<210> 6198
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6198
Tyr Phe Tyr Ser Arg
1 5
<210> 6199
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6199
Tyr Gly Ala Ala Thr Phe Thr Arg
1 5
<210> 6200
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6200
Tyr Gly Ala Glu Val Lys
1 5
<210> 6201
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6201
Tyr Gly Asp Phe Asn Lys
1 5
<210> 6202
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6202
Tyr Gly Asp Asn Asn His Ser Gln Gly Val Asn Trp Phe His Trp Lys
1 5 10 15
<210> 6203
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6203
Tyr Gly Phe Cys Glu Ala Ala Asp Gln Phe His Val Leu Asp Glu Val
1 5 10 15
Arg
<210> 6204
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6204
Tyr Gly Phe Cys Glu Ala Ala Asp Gln Phe His Val Leu Asp Glu Val
1 5 10 15
Arg Arg
<210> 6205
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6205
Tyr Gly Phe Ile Glu Gly His Val Val Ile Pro Arg
1 5 10
<210> 6206
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6206
Tyr Gly Phe Tyr Thr His Val Phe Arg
1 5
<210> 6207
<211> 26
<212> PRT
<213> Homo sapiens
<400> 6207
Tyr Gly Gly Gly Phe Tyr Ser Thr Gln Asp Thr Ile Asn Ala Ile Glu
1 5 10 15
Gly Leu Thr Glu Tyr Ser Leu Leu Val Lys
20 25
<210> 6208
<211> 29
<212> PRT
<213> Homo sapiens
<400> 6208
Tyr Gly Gly Gly Phe Tyr Ser Thr Gln Asp Thr Ile Asn Ala Ile Glu
1 5 10 15
Gly Leu Thr Glu Tyr Ser Leu Leu Val Lys Gln Leu Arg
20 25
<210> 6209
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6209
Tyr Gly Gly Leu Lys
1 5
<210> 6210
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6210
Tyr Gly Gly Pro Asn His His Leu Pro Leu Pro Asp Asn Trp Lys
1 5 10 15
<210> 6211
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6211
Tyr Gly Gly Pro Tyr His Ile Gly Gly Ser Pro Phe Lys
1 5 10
<210> 6212
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6212
Tyr Gly His Ser Leu Ala Leu Tyr Lys
1 5
<210> 6213
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6213
Tyr Gly His Ser Leu Ala Leu Tyr Lys Asp Lys
1 5 10
<210> 6214
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6214
Tyr Gly Ile Asp Trp Ala Ser Gly Arg
1 5
<210> 6215
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6215
Tyr Gly Ile Tyr Thr Lys
1 5
<210> 6216
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6216
Tyr Gly Leu Asp Ser Asp Leu Ser Cys Lys
1 5 10
<210> 6217
<211> 24
<212> PRT
<213> Homo sapiens
<400> 6217
Tyr Gly Leu His Asn Ile Gln Ile Ser His Leu Ser Ile Ala Ser Ser
1 5 10 15
Gln Val Glu Leu Val Glu Ala Lys
20
<210> 6218
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6218
Tyr Gly Leu Val Thr Tyr Ala Thr Tyr Pro Lys
1 5 10
<210> 6219
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6219
Tyr Gly Met Val Ala Gln Val Thr Gln Thr Leu Lys
1 5 10
<210> 6220
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6220
Tyr Gly Met Trp Thr Ile Lys
1 5
<210> 6221
<211> 21
<212> PRT
<213> Homo sapiens
<400> 6221
Tyr Gly Asn Gln Val Ser Glu His Thr Leu Gly Thr Val His Thr His
1 5 10 15
Ser Ala His Phe Lys
20
<210> 6222
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6222
Tyr Gly Pro Ile Ile Lys
1 5
<210> 6223
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6223
Tyr Gly Gln Pro Leu Pro Gly Tyr Thr Thr Lys
1 5 10
<210> 6224
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6224
Tyr Gly Gln Thr Ile Arg Pro Ile Cys Leu Pro Cys Thr Glu Gly Thr
1 5 10 15
Thr Arg
<210> 6225
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6225
Tyr Gly Arg Asn Gln Gly Asn Thr Trp Leu Thr Ala Phe Val Leu Lys
1 5 10 15
<210> 6226
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6226
Tyr Gly Thr Leu Phe Thr Met Asp Arg
1 5
<210> 6227
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6227
Tyr Gly Val Tyr Ser Tyr Ile His His Asn Lys
1 5 10
<210> 6228
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6228
Tyr Gly Tyr Thr His Leu Ser Thr Gly Asp Leu Leu Arg
1 5 10
<210> 6229
<211> 25
<212> PRT
<213> Homo sapiens
<400> 6229
Tyr His Phe Glu Ala Leu Ala Asp Thr Gly Ile Ser Ser Glu Phe Tyr
1 5 10 15
Asp Asn Ala Asn Asp Leu Leu Ser Lys
20 25
<210> 6230
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6230
Tyr His Phe Phe Leu Tyr Lys
1 5
<210> 6231
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6231
Tyr His Phe Pro Ser Leu Phe Phe Arg
1 5
<210> 6232
<211> 22
<212> PRT
<213> Homo sapiens
<400> 6232
Tyr His Phe Val Thr Pro Leu Thr Ser Met Val Val Thr Lys Pro Glu
1 5 10 15
Asp Asn Glu Asp Glu Arg
20
<210> 6233
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6233
Tyr His Gly Asp Pro Met Pro Cys Pro Lys
1 5 10
<210> 6234
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6234
Tyr His Gly Tyr Ile Phe Gly Phe Tyr Lys
1 5 10
<210> 6235
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6235
Tyr His Ile Gly Asp Glu Ile Leu Val Ser Gly Gly Ile Gly Ala Leu
1 5 10 15
Val Arg
<210> 6236
<211> 27
<212> PRT
<213> Homo sapiens
<400> 6236
Tyr His Gln Asp Thr Gln Gly Trp Gly Asp Ile Gly Tyr Ser Phe Val
1 5 10 15
Val Gly Ser Asp Gly Tyr Val Tyr Glu Gly Arg
20 25
<210> 6237
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6237
Tyr His Trp Glu His Thr Gly Leu Thr Leu Arg
1 5 10
<210> 6238
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6238
Tyr Ile Ala Gln Leu Lys
1 5
<210> 6239
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6239
Tyr Ile Ala Tyr Leu Val Arg
1 5
<210> 6240
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6240
Tyr Ile Cys Glu Asn Gln Asp Ser Ile Ser Ser Lys
1 5 10
<210> 6241
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6241
Tyr Ile Asp Gln Glu Glu Leu Asn Lys
1 5
<210> 6242
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6242
Tyr Ile Glu Asp Lys
1 5
<210> 6243
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6243
Tyr Ile Glu Thr Asp Pro Ala Asn Arg Asp Arg
1 5 10
<210> 6244
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6244
Tyr Ile Phe Phe Lys
1 5
<210> 6245
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6245
Tyr Ile Phe His Asn Phe Met Glu Arg
1 5
<210> 6246
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6246
Tyr Ile Phe Ser Asp Asp Ser Ser Gln Leu Thr Ile Lys
1 5 10
<210> 6247
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6247
Tyr Ile Ile Leu Leu Leu Gly Lys
1 5
<210> 6248
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6248
Tyr Ile Leu Val Ser Leu Ile Leu Leu Gly Lys
1 5 10
<210> 6249
<211> 21
<212> PRT
<213> Homo sapiens
<400> 6249
Tyr Ile Pro Tyr Thr Leu Tyr Ser Val Phe Asn Pro Ser Asp His Asp
1 5 10 15
Leu Val Leu Ile Arg
20
<210> 6250
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6250
Tyr Ile Ser Lys Tyr Glu Leu Asp Lys
1 5
<210> 6251
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6251
Tyr Ile Ser Gln Met Lys
1 5
<210> 6252
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6252
Tyr Ile Tyr Gly Lys Pro Val Gln Gly Val Ala Tyr Val Arg
1 5 10
<210> 6253
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6253
Tyr Ile Tyr Pro Leu Asp Ser Leu Thr Trp Ile Glu Tyr Trp Pro Arg
1 5 10 15
<210> 6254
<211> 25
<212> PRT
<213> Homo sapiens
<400> 6254
Tyr Lys Ala Glu Glu His Thr Val Val Leu Thr Val Thr Gly Glu Pro
1 5 10 15
Cys His Phe Pro Phe Gln Tyr His Arg
20 25
<210> 6255
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6255
Tyr Lys Ala Thr Leu Leu Asp Ile Tyr Lys
1 5 10
<210> 6256
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6256
Tyr Lys Glu Asp Phe Ser Thr Thr Gly Thr Ala Tyr Phe Glu Val Lys
1 5 10 15
<210> 6257
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6257
Tyr Lys Glu Glu Asn Asp Asp Phe Ala Ser Phe Arg
1 5 10
<210> 6258
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6258
Tyr Lys Leu Gln Asp Phe Ser Asp Gln Leu Ser Asp Tyr Tyr Glu Lys
1 5 10 15
<210> 6259
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6259
Tyr Lys Pro Glu Ser Glu Glu Leu Thr Ala Glu Arg
1 5 10
<210> 6260
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6260
Tyr Lys Pro Thr Pro Ile Pro Ile Lys
1 5
<210> 6261
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6261
Tyr Leu Ala Ala Leu Gln Leu Leu Gln Lys
1 5 10
<210> 6262
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6262
Tyr Leu Ala Glu Phe Ala Thr Gly Asn Asp Arg Lys
1 5 10
<210> 6263
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6263
Tyr Leu Ala Glu Val Ala Ala Gly Asp Asp Lys
1 5 10
<210> 6264
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6264
Tyr Leu Ala Glu Val Ala Ala Gly Asp Asp Lys Lys
1 5 10
<210> 6265
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6265
Tyr Leu Ala Glu Val Ala Thr Gly Glu Lys
1 5 10
<210> 6266
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6266
Tyr Leu Asp Glu Lys
1 5
<210> 6267
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6267
Tyr Leu Asp Phe Val Phe Ala Val Lys
1 5
<210> 6268
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6268
Tyr Leu Asp Lys Thr Glu Gln Trp Ser Thr Leu Pro Pro Glu Thr Lys
1 5 10 15
<210> 6269
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6269
Tyr Leu Asp Ser Thr Phe Thr Lys
1 5
<210> 6270
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6270
Tyr Leu Asp Trp Ile His Gly His Ile Arg
1 5 10
<210> 6271
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6271
Tyr Leu Glu Asp Lys
1 5
<210> 6272
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6272
Tyr Leu Glu Ser Ala Gly Ala Arg
1 5
<210> 6273
<211> 23
<212> PRT
<213> Homo sapiens
<400> 6273
Tyr Leu Glu Val Gln Tyr Lys Pro Gln Val His Ile Gln Met Thr Tyr
1 5 10 15
Pro Leu Gln Gly Leu Thr Arg
20
<210> 6274
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6274
Tyr Leu Phe Leu Asn Gly Asn Lys
1 5
<210> 6275
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6275
Tyr Leu Phe Gln Ile Leu Arg
1 5
<210> 6276
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6276
Tyr Leu Gly Glu Glu Tyr Val Lys
1 5
<210> 6277
<211> 45
<212> PRT
<213> Homo sapiens
<400> 6277
Tyr Leu His Thr Ala Val Ile Val Ser Gly Thr Met Leu Val Phe Gly
1 5 10 15
Gly Asn Thr His Asn Asp Thr Ser Met Ser His Gly Ala Lys Cys Phe
20 25 30
Ser Ser Asp Phe Met Ala Tyr Asp Ile Ala Cys Asp Arg
35 40 45
<210> 6278
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6278
Tyr Leu Ile Val Val Arg Pro Ala Pro Pro Pro Ser Gln Lys
1 5 10
<210> 6279
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6279
Tyr Leu Leu Lys Gly Glu Tyr Val Gly Lys
1 5 10
<210> 6280
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6280
Tyr Leu Leu Arg Pro Leu Gly Pro His Gly Leu Leu Ser Lys
1 5 10
<210> 6281
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6281
Tyr Leu Pro Cys Ser Val Leu Arg
1 5
<210> 6282
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6282
Tyr Leu Gln Glu Ile Tyr Asn Ser Asn Asn Gln Lys
1 5 10
<210> 6283
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6283
Tyr Leu Gln Gly Ser Ser Val Gln Leu Arg
1 5 10
<210> 6284
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6284
Tyr Leu Gln Thr Leu Thr Thr Ile Ala Ala Glu Lys
1 5 10
<210> 6285
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6285
Tyr Leu Ser Asp His Ser Phe Leu Val Ser Gln Gly Asp Arg
1 5 10
<210> 6286
<211> 34
<212> PRT
<213> Homo sapiens
<400> 6286
Tyr Leu Ser Asp His Ser Phe Leu Val Ser Gln Gly Asp Arg Glu Gln
1 5 10 15
Ala Pro Asn Leu Val Tyr Met Val Thr Gly Asn Pro Ala Ser Asp Glu
20 25 30
Ile Lys
<210> 6287
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6287
Tyr Leu Ser Phe His Phe Lys
1 5
<210> 6288
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6288
Tyr Leu Ser Gln Leu Lys
1 5
<210> 6289
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6289
Tyr Leu Ser Gln Met Lys
1 5
<210> 6290
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6290
Tyr Leu Thr Leu Asn Thr Glu Ser Thr Arg
1 5 10
<210> 6291
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6291
Tyr Leu Thr Ser Glu Met His Gly Ala Arg Pro Gly Ala Ser Lys
1 5 10 15
<210> 6292
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6292
Tyr Leu Thr Val Ala Ala Val Phe Arg
1 5
<210> 6293
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6293
Tyr Leu Trp Leu His Leu Arg
1 5
<210> 6294
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6294
Tyr Leu Tyr Glu Ile Ala Arg
1 5
<210> 6295
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6295
Tyr Leu Tyr His Gly Gln Thr Leu Glu Thr Leu Gly Gly Lys
1 5 10
<210> 6296
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6296
Tyr Leu Tyr His Gly Gln Thr Leu Glu Thr Leu Gly Gly Lys Lys
1 5 10 15
<210> 6297
<211> 25
<212> PRT
<213> Homo sapiens
<400> 6297
Tyr Leu Tyr Ile Ala Val Thr Val Ile Glu Ser Thr Gly Gly Phe Ser
1 5 10 15
Glu Glu Ala Glu Ile Pro Gly Ile Lys
20 25
<210> 6298
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6298
Tyr Leu Tyr Leu Arg Asn Asn Gln Ile Asp His Ile Asp Glu Lys
1 5 10 15
<210> 6299
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6299
Tyr Asn Ala Glu Lys Pro Lys
1 5
<210> 6300
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6300
Tyr Asn Ala Leu Asp Leu Thr Asn Asn Gly Lys
1 5 10
<210> 6301
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6301
Tyr Asn Glu Leu Leu Lys
1 5
<210> 6302
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6302
Tyr Asn Glu Gln His Val Pro Gly Ser Pro Phe Thr Ala Arg
1 5 10
<210> 6303
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6303
Tyr Asn Phe Ser Phe Arg
1 5
<210> 6304
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6304
Tyr Asn Ile Leu Pro Glu Lys
1 5
<210> 6305
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6305
Tyr Asn Ile Leu Pro Glu Lys Glu Asp Ser Pro Phe Ala Leu Lys
1 5 10 15
<210> 6306
<211> 27
<212> PRT
<213> Homo sapiens
<400> 6306
Tyr Asn Ile Leu Pro Glu Lys Glu Glu Phe Pro Phe Ala Leu Gly Val
1 5 10 15
Gln Thr Leu Pro Gln Thr Cys Asp Glu Pro Lys
20 25
<210> 6307
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6307
Tyr Asn Leu Leu Pro Glu Lys
1 5
<210> 6308
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6308
Tyr Asn Pro Gly His Leu Leu Pro His Lys
1 5 10
<210> 6309
<211> 22
<212> PRT
<213> Homo sapiens
<400> 6309
Tyr Asn Pro Ile Pro Ser Val Gln Leu Met Gly Asn Gly Phe His Phe
1 5 10 15
Leu Ala Gly Glu Pro Arg
20
<210> 6310
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6310
Tyr Asn Pro Ser Leu Lys
1 5
<210> 6311
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6311
Tyr Asn Pro Val Val Ile Asp Phe Glu Met Gln Pro Ile His Glu Val
1 5 10 15
Leu Arg
<210> 6312
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6312
Tyr Asn Gln Ala Thr Pro Asn Phe His Gln Trp Arg
1 5 10
<210> 6313
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6313
Tyr Asn Ser Gln Asn Gln Ser Asn Asn Gln Phe Val Leu Tyr Arg
1 5 10 15
<210> 6314
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6314
Tyr Asn Trp Arg Glu Asn Leu Asp Arg
1 5
<210> 6315
<211> 22
<212> PRT
<213> Homo sapiens
<400> 6315
Tyr Pro Ala Leu His Lys Pro Glu Asn Gln Asp Ile Asp Trp Gly Ala
1 5 10 15
Leu Glu Gly Glu Thr Arg
20
<210> 6316
<211> 25
<212> PRT
<213> Homo sapiens
<400> 6316
Tyr Pro Ala Leu His Lys Pro Glu Asn Gln Asp Ile Asp Trp Gly Ala
1 5 10 15
Leu Glu Gly Glu Thr Arg Glu Glu Arg
20 25
<210> 6317
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6317
Tyr Pro Gly Ile Lys
1 5
<210> 6318
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6318
Tyr Pro His Tyr Phe Pro Leu Leu Lys
1 5
<210> 6319
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6319
Tyr Pro Ile Glu His Gly Ile Ile Thr Asn Trp Asp Asp Met Glu Lys
1 5 10 15
<210> 6320
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6320
Tyr Pro Leu Val Val Phe Ser His Gly Leu Gly Ala Phe Arg
1 5 10
<210> 6321
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6321
Tyr Pro Leu Tyr Val Leu Lys
1 5
<210> 6322
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6322
Tyr Pro Pro Thr Val Ser Met Val Glu Gly Gln Gly Glu Lys
1 5 10
<210> 6323
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6323
Tyr Pro Gln Glu Asn Lys
1 5
<210> 6324
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6324
Tyr Pro Ser Ile Gly Gln Leu Lys
1 5
<210> 6325
<211> 19
<212> PRT
<213> Homo sapiens
<400> 6325
Tyr Pro Ser Leu Ser Ile His Gly Ile Glu Gly Ala Phe Asp Glu Pro
1 5 10 15
Gly Thr Lys
<210> 6326
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6326
Tyr Pro Val Ala His Phe Ile Asp Gln Thr Leu Lys
1 5 10
<210> 6327
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6327
Tyr Pro Val Gly Val His Phe Leu Pro Lys
1 5 10
<210> 6328
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6328
Tyr Pro Val Tyr Gly Val Gln Trp His Pro Glu Lys
1 5 10
<210> 6329
<211> 19
<212> PRT
<213> Homo sapiens
<400> 6329
Tyr Gln Ala Glu Phe Pro Met Ser Pro Val Thr Ser Ala His Ala Gly
1 5 10 15
Thr Tyr Arg
<210> 6330
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6330
Tyr Gln Phe Phe Val Tyr Leu Gln Glu Gly Lys
1 5 10
<210> 6331
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6331
Tyr Gln Ile Ser Val Asn Lys
1 5
<210> 6332
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6332
Tyr Gln Ile Ser Val Asn Lys Tyr Arg
1 5
<210> 6333
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6333
Tyr Gln Ile Trp Thr Thr Val Val Asp Trp Ile His Pro Asp Leu Lys
1 5 10 15
<210> 6334
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6334
Tyr Gln Ile Trp Thr Thr Val Val Asp Trp Ile His Pro Asp Leu Lys
1 5 10 15
Arg
<210> 6335
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6335
Tyr Gln Ser His Asp Tyr Ala Phe Ser Ser Val Glu Lys
1 5 10
<210> 6336
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6336
Tyr Gln Tyr Asn Thr Asp Val Val Phe Asp Ser Gln Gly Lys
1 5 10
<210> 6337
<211> 28
<212> PRT
<213> Homo sapiens
<400> 6337
Tyr Arg Gly Asp Gln Asp Ala Thr Met Ser Ile Leu Asp Ile Ser Met
1 5 10 15
Met Thr Gly Phe Ala Pro Asp Thr Asp Asp Leu Lys
20 25
<210> 6338
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6338
Tyr Ser Ala Glu Leu His Val Ala His Trp Asn Ser Ala Lys
1 5 10
<210> 6339
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6339
Tyr Ser Ala Trp Ala Glu Ser Val Thr Asn Leu Pro Gln Val Ile Lys
1 5 10 15
<210> 6340
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6340
Tyr Ser Asp Val Ile Ala Gly Gln Phe Tyr Gly His Thr His Arg
1 5 10 15
<210> 6341
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6341
Tyr Ser Phe Cys Thr Asp His Thr Val Leu Val Gln Thr Arg
1 5 10
<210> 6342
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6342
Tyr Ser Phe Thr Ile Glu Leu Arg
1 5
<210> 6343
<211> 19
<212> PRT
<213> Homo sapiens
<400> 6343
Tyr Ser His Tyr Asn Glu Arg Asp Glu Ile Pro His Asn Asp Ile Ala
1 5 10 15
Leu Leu Lys
<210> 6344
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6344
Tyr Ser Leu Glu Leu Lys
1 5
<210> 6345
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6345
Tyr Ser Leu Glu Pro Val Ala Val Glu Leu Lys
1 5 10
<210> 6346
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6346
Tyr Ser Leu Asn Ser Gly Ala Val Lys
1 5
<210> 6347
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6347
Tyr Ser Leu Thr Tyr Ile Tyr Thr Gly Leu Ser Lys
1 5 10
<210> 6348
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6348
Tyr Ser Leu Trp Phe Lys
1 5
<210> 6349
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6349
Tyr Ser Pro Gly Gly Thr Pro Thr Ala Ile Lys
1 5 10
<210> 6350
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6350
Tyr Ser Pro Val Lys
1 5
<210> 6351
<211> 50
<212> PRT
<213> Homo sapiens
<400> 6351
Tyr Ser Pro Val Lys Asn Glu Glu Asp Val Ala Glu Leu Ser Ile Ser
1 5 10 15
Pro Ser Asp Asn Ala Val Val Leu Thr Asn Leu Leu Pro Gly Thr Glu
20 25 30
Tyr Val Val Ser Val Ser Ser Val Tyr Glu Gln His Glu Ser Thr Pro
35 40 45
Leu Arg
50
<210> 6352
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6352
Tyr Ser Ser Leu Ala Glu Ala Ala Ser Lys
1 5 10
<210> 6353
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6353
Tyr Ser Val Asp Glu Lys
1 5
<210> 6354
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6354
Tyr Thr Ala Cys Glu Thr Ala Arg
1 5
<210> 6355
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6355
Tyr Thr Ala Ser Gly Val His Lys
1 5
<210> 6356
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6356
Tyr Thr Cys Leu Pro Gly Tyr Val Arg
1 5
<210> 6357
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6357
Tyr Thr Phe Glu Leu Ser Arg
1 5
<210> 6358
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6358
Tyr Thr Gly Asn Thr Tyr Arg
1 5
<210> 6359
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6359
Tyr Thr His Phe Leu Thr Gln His Tyr Asp Ala Lys Pro Gln Gly Arg
1 5 10 15
<210> 6360
<211> 27
<212> PRT
<213> Homo sapiens
<400> 6360
Tyr Thr His Gly His Gly Ser Glu Thr Leu Tyr Leu Ala Pro Gly Gly
1 5 10 15
Gly Asp Asp Trp Ile Tyr Asp Leu Gly Ile Lys
20 25
<210> 6361
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6361
Tyr Thr His Leu Lys
1 5
<210> 6362
<211> 22
<212> PRT
<213> Homo sapiens
<400> 6362
Tyr Thr Ile Ala Ala Leu Leu Ser Pro Tyr Ser Tyr Ser Thr Thr Ala
1 5 10 15
Val Val Thr Asn Pro Lys
20
<210> 6363
<211> 23
<212> PRT
<213> Homo sapiens
<400> 6363
Tyr Thr Ile Ala Ala Leu Leu Ser Pro Tyr Ser Tyr Ser Thr Thr Ala
1 5 10 15
Val Val Thr Asn Pro Lys Glu
20
<210> 6364
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6364
Tyr Thr Leu Phe Gln Ile Phe Ser Lys
1 5
<210> 6365
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6365
Tyr Thr Leu Asn Ile Leu Glu Glu Ile Gly Gly Gly Gln Lys
1 5 10
<210> 6366
<211> 5
<212> PRT
<213> Homo sapiens
<400> 6366
Tyr Thr Leu Asn Lys
1 5
<210> 6367
<211> 22
<212> PRT
<213> Homo sapiens
<400> 6367
Tyr Thr Pro Ser Gly Gln Ala Gly Ala Ala Ala Ser Glu Ser Leu Phe
1 5 10 15
Val Ser Asn His Ala Tyr
20
<210> 6368
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6368
Tyr Thr Thr Glu Ile Ile Lys
1 5
<210> 6369
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6369
Tyr Thr Thr Thr Met Gly Val Asn Thr Tyr Lys
1 5 10
<210> 6370
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6370
Tyr Thr Thr Thr Met Gly Val Asn Thr Tyr Lys Ala Arg
1 5 10
<210> 6371
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6371
Tyr Thr Val Asn Gln Cys Arg
1 5
<210> 6372
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6372
Tyr Thr Tyr Asn Tyr Glu Ala Glu Ser Ser Ser Gly Val Pro Gly Thr
1 5 10 15
Ala Asp Ser Arg
20
<210> 6373
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6373
Tyr Val Ala Thr Leu Gly Val Glu Val His Pro Leu Val Phe His Thr
1 5 10 15
Asn Arg
<210> 6374
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6374
Tyr Val Gly Gly Gln Glu His Phe Ala His Leu Leu Ile Leu Arg
1 5 10 15
<210> 6375
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6375
Tyr Val Gly Gly Gln Glu His Phe Ala His Leu Leu Ile Leu Arg Asp
1 5 10 15
Thr Lys
<210> 6376
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6376
Tyr Val Gly Asn Met His Gly Asn Glu Ala Leu Gly Arg
1 5 10
<210> 6377
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6377
Tyr Val His Gly Val Arg
1 5
<210> 6378
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6378
Tyr Val Leu Pro Asn Phe Glu Val Lys
1 5
<210> 6379
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6379
Tyr Val Leu Ser Pro Tyr Lys
1 5
<210> 6380
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6380
Tyr Val Asn Glu Ala Val Lys
1 5
<210> 6381
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6381
Tyr Val Asn Trp Ile Lys
1 5
<210> 6382
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6382
Tyr Val Gln Gly Leu Lys
1 5
<210> 6383
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6383
Tyr Val Arg Pro Gly Gly Gly Phe Val Pro Asn Phe Gln Leu Phe Glu
1 5 10 15
Lys
<210> 6384
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6384
Tyr Val Ser Glu Leu His Leu Thr Arg
1 5
<210> 6385
<211> 23
<212> PRT
<213> Homo sapiens
<400> 6385
Tyr Val Ser His Phe Glu Thr Glu Gly Pro His Val Leu Leu Tyr Phe
1 5 10 15
Asp Ser Val Pro Thr Ser Arg
20
<210> 6386
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6386
Tyr Val Val Ile Ser Gln Gly Leu Asp Lys Pro Arg
1 5 10
<210> 6387
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6387
Tyr Val Tyr Ile Ala Glu Leu Leu Ala His Lys
1 5 10
<210> 6388
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6388
Tyr Val Tyr Ile Ala Glu Leu Leu Ala His Lys Ile His Val Tyr Glu
1 5 10 15
Lys
<210> 6389
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6389
Tyr Trp Gly Val Ala Ser Phe Leu Gln Lys
1 5 10
<210> 6390
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6390
Tyr Trp Leu Tyr Tyr Leu His Pro Val Leu Gln Arg
1 5 10
<210> 6391
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6391
Tyr Tyr Ala Asp Ser Val Lys
1 5
<210> 6392
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6392
Tyr Tyr Ala Gly Gly Cys Ser Pro His Tyr Ile Leu Asn Thr Arg
1 5 10 15
<210> 6393
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6393
Tyr Tyr Cys Phe Gln Gly Asn Gln Phe Leu Arg
1 5 10
<210> 6394
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6394
Tyr Tyr Asp Phe Lys Asn Pro Ile Ile Glu Lys
1 5 10
<210> 6395
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6395
Tyr Tyr Glu Leu Glu Glu Lys
1 5
<210> 6396
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6396
Tyr Tyr Ile Ala Ala Ser Tyr Val Lys
1 5
<210> 6397
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6397
Tyr Tyr Ile Glu Gln Lys
1 5
<210> 6398
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6398
Tyr Tyr Leu Gln Gly Ala Lys
1 5
<210> 6399
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6399
Tyr Tyr Pro Tyr Gln Ser Phe Gln Thr Pro Gln His Pro Ser Phe Leu
1 5 10 15
Phe Gln Asp Lys
20
<210> 6400
<211> 21
<212> PRT
<213> Homo sapiens
<400> 6400
Tyr Tyr Pro Tyr Gln Ser Phe Gln Thr Pro Gln His Pro Ser Phe Leu
1 5 10 15
Phe Gln Asp Lys Arg
20
<210> 6401
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6401
Tyr Tyr Arg Ala Gly Leu Leu Gln Lys
1 5
<210> 6402
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6402
Tyr Tyr Thr Tyr Leu Ile Met Asn Lys
1 5
<210> 6403
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6403
Tyr Tyr Trp Gly Gly Gln Tyr Thr Trp Asp Met Ala Lys
1 5 10
<210> 6404
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6404
Tyr Tyr Tyr Asp Gly Lys
1 5
<210> 6405
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6405
Tyr Tyr Tyr Asp Gly Lys Asp Tyr Ile Glu Phe Asn Lys
1 5 10
<210> 6406
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6406
Ala Ala Leu Gly Val Leu Gly Pro Glu Val Glu Lys
1 5 10
<210> 6407
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6407
Ala Cys Ile Asp Ser Asn Glu Asp Gly Asp Leu Ser Lys
1 5 10
<210> 6408
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6408
Ala Phe Gly Phe Ser His Leu Glu Ala Leu Leu Asp Asp Ser Lys
1 5 10 15
<210> 6409
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6409
Ala Phe Ile Asp Val Thr Ala Ala Ala Glu Asn Ile Arg
1 5 10
<210> 6410
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6410
Ala Phe Ser Gly Tyr Leu Gly Thr Asp Gln Ser Lys
1 5 10
<210> 6411
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6411
Ala Ile Asn Pro Ile Asn Thr Phe Thr Lys
1 5 10
<210> 6412
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6412
Ala Ile Tyr Pro Phe Asp Gly His Asn Glu Gly Thr Leu Ala Met Lys
1 5 10 15
<210> 6413
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6413
Ala Leu Gly Gln Asn Pro Thr Asn Ala Glu Val Leu Lys
1 5 10
<210> 6414
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6414
Ala Leu Pro Phe Trp Asn Glu Glu Ile Val Pro Gln Ile Lys
1 5 10
<210> 6415
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6415
Ala Met Glu Ala Val Ala Ala Gln Gly Lys
1 5 10
<210> 6416
<211> 23
<212> PRT
<213> Homo sapiens
<400> 6416
Ala Met Leu Ala Ala Val Leu Glu Gln Glu Leu Pro Ala Leu Ala Glu
1 5 10 15
Asn Leu His Gln Glu Gln Lys
20
<210> 6417
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6417
Ala Pro Phe Ala Ala Pro Ser Pro Phe Ala Glu Leu Val Leu Pro Pro
1 5 10 15
Gln Gln
<210> 6418
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6418
Ala Ser Ala Gln Thr Leu Leu Gly Asp Pro Phe Leu Gln Pro Gly Lys
1 5 10 15
<210> 6419
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6419
Ala Thr Asp Ala Glu Ala Asp Val Ala Ser Leu Asn Arg
1 5 10
<210> 6420
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6420
Ala Val Ala Ile Asp Leu Pro Gly Leu Gly His Ser Lys
1 5 10
<210> 6421
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6421
Ala Tyr Asp Tyr Leu Val Gln Asn Thr Ser Phe Ala Asn Lys
1 5 10
<210> 6422
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6422
Cys Gly Asp Leu Glu Glu Glu Leu Lys Asn Val Thr Asn Asn Leu Lys
1 5 10 15
<210> 6423
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6423
Cys Ser Gln Ala Val Tyr Ala Ala Glu Lys
1 5 10
<210> 6424
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6424
Cys Tyr Thr Ala Val Val Pro Leu Val Tyr Gly Gly Glu Thr Lys
1 5 10 15
<210> 6425
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6425
Asp Ala Gly Pro Leu Leu Ile Ser Leu Lys
1 5 10
<210> 6426
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6426
Asp Ala Val Pro Ala Phe Ile Glu Pro Asn Val Arg
1 5 10
<210> 6427
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6427
Asp Phe Asn Val Pro Leu Ser Ile Ser Arg
1 5 10
<210> 6428
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6428
Asp Gly Gly Leu Ile Cys Thr Ser Cys Arg
1 5 10
<210> 6429
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6429
Asp Gly Asn Gly Tyr Ile Ser Ala Ala Glu Leu Arg
1 5 10
<210> 6430
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6430
Asp Gly Trp Gln Asp Ile Val Ile Gly Ala Pro Gln Tyr Phe Asp Arg
1 5 10 15
<210> 6431
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6431
Asp Ile Ala Ala Asn Glu Glu Asn Arg
1 5
<210> 6432
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6432
Asp Ile Ala Leu Glu Ile Thr Val Thr Asn Ser Pro Ser Asn Pro Arg
1 5 10 15
<210> 6433
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6433
Asp Ile Ile Gly Leu Tyr Leu Glu Gln Lys
1 5 10
<210> 6434
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6434
Asp Leu Val Val Gln Gln Leu Val Asn Val Ser Arg
1 5 10
<210> 6435
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6435
Asp Met Ala His Gln Val Gln Glu Leu Phe Arg
1 5 10
<210> 6436
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6436
Asp Asn Ser Gln Val Asn Ala Val Thr Val Leu Thr Leu Leu Asp Lys
1 5 10 15
<210> 6437
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6437
Asp Pro Asn Asn Leu Leu Asn Asp Trp Ser Gln Lys
1 5 10
<210> 6438
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6438
Asp Gln Gly Thr Tyr Glu Asp Tyr Val Glu Gly Leu Arg
1 5 10
<210> 6439
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6439
Asp Arg Pro Phe Phe Pro Gly Leu Val Lys
1 5 10
<210> 6440
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6440
Asp Ser Thr Leu Ile Met Gln Leu Leu Arg
1 5 10
<210> 6441
<211> 19
<212> PRT
<213> Homo sapiens
<400> 6441
Asp Val Thr Ala Thr Val Asp Ser Leu Pro Leu Ile Thr Ala Ser Ile
1 5 10 15
Leu Ser Lys
<210> 6442
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6442
Asp Val Thr Phe Ser Pro Ala Thr Ile Glu Asn Glu Leu Ile Lys
1 5 10 15
<210> 6443
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6443
Glu Ala Ser Met Val Ile Thr Glu Ser Pro Ala Ala Leu Gln Leu Arg
1 5 10 15
<210> 6444
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6444
Glu Gly Glu Val Leu Tyr Ile Ile Glu Glu Asp Lys
1 5 10
<210> 6445
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6445
Glu Gly His Val Glu Thr Val Leu Ala Leu Leu Glu Lys
1 5 10
<210> 6446
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6446
Glu Gly Met Asn Ile Val Glu Ala Met Glu Arg
1 5 10
<210> 6447
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6447
Glu Gly Asn Gly Thr Val Met Gly Ala Glu Ile Arg
1 5 10
<210> 6448
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6448
Glu Gly Thr Ile Gln Val Gln Gly Gln Ala Leu Phe Phe Arg
1 5 10
<210> 6449
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6449
Glu His Leu Pro Leu Ile Gly Lys
1 5
<210> 6450
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6450
Glu His Val Asn Val Val Phe Ile Gly His Val Asp Ala Gly Lys
1 5 10 15
<210> 6451
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6451
Glu Ile His Thr Val Pro Asp Met Gly Lys
1 5 10
<210> 6452
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6452
Glu Leu Phe Leu Thr His Gly Asn Leu Glu Glu Val Ala Glu Lys
1 5 10 15
<210> 6453
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6453
Glu Leu Gly Thr Gly Gln Phe Gly Val Val Lys
1 5 10
<210> 6454
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6454
Glu Leu His Ile Gln Gly Asn Arg
1 5
<210> 6455
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6455
Glu Leu Leu Met Asn Gly Thr Ser Ser Thr Ala Glu Ala Ile Gly Leu
1 5 10 15
Lys
<210> 6456
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6456
Glu Asn Ala Gln Leu Leu Asn Met Pro Val Val Lys
1 5 10
<210> 6457
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6457
Glu Pro Val Gln Ile Glu Leu Ser Pro Pro Met Glu Val Val Gln Lys
1 5 10 15
<210> 6458
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6458
Glu Gln Ala Glu Ala Glu Val Ala Ser Leu Asn Arg
1 5 10
<210> 6459
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6459
Glu Ser Ala Gly Leu Ile Pro Ser Pro Glu Leu Gln Glu Trp Arg
1 5 10 15
<210> 6460
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6460
Glu Ser Gln Val Tyr Leu Leu Gly Thr Gly Leu Arg
1 5 10
<210> 6461
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6461
Glu Thr Ser Gly Asn Leu Glu Gln Leu Leu Leu Ala Val Val Lys
1 5 10 15
<210> 6462
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6462
Glu Thr Thr Gly Val Met Val Leu Ala Trp Asp Lys
1 5 10
<210> 6463
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6463
Glu Val Ala Gly Phe Val Leu Asn Arg
1 5
<210> 6464
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6464
Glu Val Pro Phe Ala Asp Leu Ser Asn Met Glu Ile Gly Met Lys
1 5 10 15
<210> 6465
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6465
Glu Tyr Ala Glu Asp Asp Asn Ile Tyr Gln Gln Lys
1 5 10
<210> 6466
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6466
Phe Ala Thr Gly Asp Ile Ile Gln Ile Ile Asn Lys
1 5 10
<210> 6467
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6467
Phe Cys Gly Trp Phe Asp Ala Glu Leu Ser Glu Lys
1 5 10
<210> 6468
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6468
Phe Glu Gln Ser Ala Ser Asn Phe Tyr Gln Gln Gln Ala Glu Gly His
1 5 10 15
Lys
<210> 6469
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6469
Phe Phe Glu His Phe Ile Glu Gly Gly Arg
1 5 10
<210> 6470
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6470
Phe Gly Gly Ala Ala Val Phe Pro Asn Gln Glu Gln Ala Arg
1 5 10
<210> 6471
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6471
Phe Gly Ser Cys Gln Gln Gly Val Ala Ala Thr Phe Thr Lys
1 5 10
<210> 6472
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6472
Phe Gly Ser Leu Leu Pro Ile His Pro Val Thr Ser Gly
1 5 10
<210> 6473
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6473
Phe Leu Ala Thr Glu Val Ser Gln Phe Ser Pro Ser Leu Ile Ser Glu
1 5 10 15
Lys
<210> 6474
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6474
Phe Leu Leu Gln His Gln Ala Asp Val Asn Ala Lys
1 5 10
<210> 6475
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6475
Phe Leu Asn Leu Thr Glu Asn Asp Ile Gln Lys
1 5 10
<210> 6476
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6476
Phe Asn Ser Val Glu Lys
1 5
<210> 6477
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6477
Phe Gln Asp Asn Leu Asp Phe Ile Gln Trp Phe Lys
1 5 10
<210> 6478
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6478
Phe Ser Ser Glu Thr Trp Gln Asn Leu Gly Thr Leu His Arg
1 5 10
<210> 6479
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6479
Phe Thr Asn Ser Glu Thr Ala Glu His Ile Ala Gln Gly Leu Arg
1 5 10 15
<210> 6480
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6480
Gly Ala Glu Glu Met Glu Thr Val Ile Pro Val Asp Val Met Arg
1 5 10 15
<210> 6481
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6481
Gly Ala Gly Pro Gly Cys Tyr Leu Ala Gly Ser Leu Thr Leu Ser Lys
1 5 10 15
<210> 6482
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6482
Gly Asp Asn Val Leu Ile Asn Thr Phe Ser Gly Leu Leu Lys
1 5 10
<210> 6483
<211> 19
<212> PRT
<213> Homo sapiens
<400> 6483
Gly Glu Glu Gln Ser Ala Ile Pro Tyr Phe Pro Phe Ile Pro Asp Gln
1 5 10 15
Pro Phe Arg
<210> 6484
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6484
Gly Glu Gly Gly Thr Thr Asn Pro His Ile Phe Pro Glu Gly Ser Glu
1 5 10 15
Pro Lys
<210> 6485
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6485
Gly Gly Ala Gly Gly Gly Pro Ser Gly Asp
1 5 10
<210> 6486
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6486
Gly His Ile Ile Ser Asp Gly Gly Cys Ser Cys Pro Gly Asp Val Ala
1 5 10 15
Lys
<210> 6487
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6487
Gly His Thr Gly Ile Lys Ser Asp Ser Leu Thr Leu Ser Glu Phe Val
1 5 10 15
Lys
<210> 6488
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6488
Gly Ile Leu His Leu Ser Pro Asp Val Tyr Gln Glu Met Glu Ala Ser
1 5 10 15
Arg
<210> 6489
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6489
Gly Leu Gly Thr Asp Glu Glu Ser Ile Leu Thr Leu Leu Thr Ser Arg
1 5 10 15
<210> 6490
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6490
Gly Leu Val Gly Glu Ile Ile Lys
1 5
<210> 6491
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6491
Gly Asn Thr Ser Gly Val Leu Val Val Leu Thr Lys
1 5 10
<210> 6492
<211> 19
<212> PRT
<213> Homo sapiens
<400> 6492
Gly Pro Gly Thr Ser Phe Glu Phe Ala Leu Ala Ile Val Glu Ala Leu
1 5 10 15
Asn Gly Lys
<210> 6493
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6493
Gly Pro Pro Ala Ser Ser Pro Ala Pro Ala Pro Lys
1 5 10
<210> 6494
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6494
Gly Gln Gly Thr Tyr Glu Asp Tyr Leu Glu Gly Phe Arg
1 5 10
<210> 6495
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6495
Gly Ser Ala Gln Met Asp Pro Pro Gln Met Gly Pro Ala Pro Thr Glu
1 5 10 15
Ala Val Gln Lys
20
<210> 6496
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6496
Gly Ser Gly Asp Ser Ser Gln Val Thr Gln Val Ser Pro Gln Arg
1 5 10 15
<210> 6497
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6497
Gly Thr Leu Thr Glu Ala Phe Pro Val Leu Gly Gly Lys
1 5 10
<210> 6498
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6498
Gly Thr Val Thr Asp Phe Pro Gly Phe Asp Glu Arg
1 5 10
<210> 6499
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6499
Gly Val Thr Phe Asn Val Thr Thr Val Asp Thr Lys
1 5 10
<210> 6500
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6500
Gly Val Val Asp Ser Glu Asp Leu Pro Leu Asn Ile Ser Arg
1 5 10
<210> 6501
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6501
Gly Tyr Gly Tyr Gly Gln Gly Ala Gly Thr Leu Ser Thr Asp Lys
1 5 10 15
<210> 6502
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6502
His Phe Thr Ile Leu Asp Ala Pro Gly His Lys
1 5 10
<210> 6503
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6503
His Phe Tyr Val Val Ile Pro Gln Ile Tyr Lys
1 5 10
<210> 6504
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6504
His Gly Leu Ala Val Gly Ala Asn Thr Ile Leu Leu Thr Lys
1 5 10
<210> 6505
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6505
His Gly Val Met Val Asp Ala Thr Thr Arg
1 5 10
<210> 6506
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6506
His Ile Phe Ala Leu Phe Asn Thr Glu Gln Arg
1 5 10
<210> 6507
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6507
His Leu Ile Glu Gln Asp Phe Pro Gly Met Arg
1 5 10
<210> 6508
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6508
His Leu Val Asn Val Tyr Tyr Leu Glu Glu Ala Ala Gln Gly Gln Glu
1 5 10 15
<210> 6509
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6509
His Gln Ile Val Glu Val Ala Gly Asp Asp Lys
1 5 10
<210> 6510
<211> 26
<212> PRT
<213> Homo sapiens
<400> 6510
His Ser Asp Leu Ala Ala Leu Tyr Thr Ile Val Ala Val Phe Pro Ser
1 5 10 15
Pro Leu Ala Ala Gln Asn Ala Ser Leu Arg
20 25
<210> 6511
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6511
His Ser Gln Phe Ile Gly Tyr Pro Ile Thr Leu Phe Val Glu Lys
1 5 10 15
<210> 6512
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6512
His Ser Ser Ile Phe Asp Gln Leu Asp Val Val Ser Tyr Glu Glu Val
1 5 10 15
Val Arg
<210> 6513
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6513
His Val Leu Gln Thr Phe Gly Pro Ile Pro Glu Phe Ser Arg
1 5 10
<210> 6514
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6514
His Val Leu Thr Thr Leu Gly Glu Lys
1 5
<210> 6515
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6515
His Val Leu Val Thr Leu Gly Glu Lys
1 5
<210> 6516
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6516
His Val Met Thr Asn Leu Gly Glu Lys
1 5
<210> 6517
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6517
Ile Cys Leu Asp Leu Gln Ala Pro Leu Tyr Lys
1 5 10
<210> 6518
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6518
Ile Phe Gly Leu Gly Trp Ala Ile Ile Leu Lys
1 5 10
<210> 6519
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6519
Ile Phe Ser Tyr Leu Asp Ala Val Ser Leu Leu Cys Thr Gly Cys Val
1 5 10 15
Ser Arg
<210> 6520
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6520
Ile Gly Asp Thr Val Ser Phe Ser Ile Glu Ala Lys
1 5 10
<210> 6521
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6521
Ile Ile Pro Gly Phe Met Cys Gln Gly Gly Asp Phe Thr Arg
1 5 10
<210> 6522
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6522
Ile Leu Ala His Leu Thr Gly Thr Glu Phe Met Gln Asp Pro Asp Glu
1 5 10 15
Glu His Leu Lys
20
<210> 6523
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6523
Ile Leu Asp Asp Trp Gly Glu Thr Cys Lys
1 5 10
<210> 6524
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6524
Ile Leu Tyr Ser Gln Cys Gly Asp Val Met Arg
1 5 10
<210> 6525
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6525
Ile Met Gly Ile Pro Glu Glu Glu Gln Met Gly Leu Leu Arg
1 5 10
<210> 6526
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6526
Ile Asn Phe Asp Ser His Glu Pro Leu Gln Ser Val Thr Asn Lys
1 5 10 15
<210> 6527
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6527
Ile Asn Gln Asp Gly Thr Phe Leu Val Arg
1 5 10
<210> 6528
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6528
Ile Gln Ala Leu Gln Gln Gln Ala Asp Glu Ala Glu Asp Arg
1 5 10
<210> 6529
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6529
Ile Gln Ala Ser Phe Arg
1 5
<210> 6530
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6530
Ile Gln Gly Phe Gln Ala Ala Leu Ser Ala Leu Lys
1 5 10
<210> 6531
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6531
Ile Gln Gln Glu Ile Ala Val Gln Asn Pro Leu Val Ser Glu Arg
1 5 10 15
<210> 6532
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6532
Ile Gln Ser Pro Thr Glu Glu Thr Glu Ile Phe Tyr His Arg
1 5 10
<210> 6533
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6533
Ile Gln Thr Leu Ser Ala Ile Asp Thr Ile Lys
1 5 10
<210> 6534
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6534
Ile Gln Val Leu Gln Gln Gln Ala Asp Asp Ala Glu Glu Arg
1 5 10
<210> 6535
<211> 21
<212> PRT
<213> Homo sapiens
<400> 6535
Ile Ser Ser Asp Cys Asp Asp Ile Leu His Leu Val Thr Asn Gln Ser
1 5 10 15
Gln Met Ile Val Lys
20
<210> 6536
<211> 10
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<220>
<221> MOD_RES
<222> (9)..(9)
<223> Oxidation
<400> 6536
Ile Ser Ser Leu Thr Ser Glu Ile Met Lys
1 5 10
<210> 6537
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6537
Ile Thr Phe Asp Ser Glu Gln Leu Gln Glu Ala Val Lys
1 5 10
<210> 6538
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6538
Lys Pro Leu Pro Pro Thr Pro Glu Glu Asp Gln Ile Leu Lys
1 5 10
<210> 6539
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6539
Leu Ala Ala Pro Gln Leu Ile Met Leu Ala Asn Val Ala Leu Thr Gly
1 5 10 15
Glu
<210> 6540
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6540
Leu Ala Leu Gln Ala Gln Pro Val Pro Asp Glu Leu Val Thr Lys
1 5 10 15
<210> 6541
<211> 23
<212> PRT
<213> Homo sapiens
<400> 6541
Leu Cys Tyr Val Ala Leu Asp Phe Glu Gln Glu Met Ala Thr Ala Ala
1 5 10 15
Ser Ser Ser Ser Leu Glu Lys
20
<210> 6542
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6542
Leu Asp Phe Lys Asp Val Leu Leu Arg Pro Lys
1 5 10
<210> 6543
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6543
Leu Glu Thr Thr Ser Asn Gln Asp Asn Leu Ala Pro Ile Thr Ala Lys
1 5 10 15
<210> 6544
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6544
Leu Glu Val Asp Ser His Ser Leu His Gly Pro Val Asn Asp Glu Glu
1 5 10 15
Ser Ser Thr Lys
20
<210> 6545
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6545
Leu Glu Val Glu Gly Lys
1 5
<210> 6546
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6546
Leu Gly Val Gly Ala Glu Leu Leu Val Asp Val Gly Gln Arg
1 5 10
<210> 6547
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6547
Leu His Gln Glu Asp Asn Asp Tyr Ile Asn Ala Ser Leu Ile Lys
1 5 10 15
<210> 6548
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6548
Leu Ile His His Pro Asp Val Ser Val Gln Ser Val Ala Asp Gln Pro
1 5 10 15
Lys
<210> 6549
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6549
Leu Leu Asp Thr Val Asp Asp Met Leu Ala Asn Asp Ile Ala Arg
1 5 10 15
<210> 6550
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6550
Leu Leu Thr Ser Gly Tyr Leu Gln Arg
1 5
<210> 6551
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6551
Leu Asn His Leu Leu Thr Asp Ile Leu Ala Asp Val Lys
1 5 10
<210> 6552
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6552
Leu Asn Val Ala Glu Val Thr Gln Ser Glu Ile Gly Gln Lys
1 5 10
<210> 6553
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6553
Leu Pro Glu Gly Asp Leu Gly Lys
1 5
<210> 6554
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6554
Leu Thr Asp Glu Glu Val Asp Glu Met Ile Arg
1 5 10
<210> 6555
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6555
Leu Val Ile Ile Glu Gly Asp Leu Glu Arg
1 5 10
<210> 6556
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6556
Leu Val Ile Asn Gly Asn Pro Ile Thr Ile Phe Gln Glu Arg
1 5 10
<210> 6557
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6557
Leu Val Pro Leu Val Gln Ala Thr Phe Pro Glu Asn Ala Val Thr Lys
1 5 10 15
<210> 6558
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6558
Leu Tyr Asp Ile Glu Gln Gln Gln Ile Arg
1 5 10
<210> 6559
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6559
Met Glu Val Asp Tyr Ser Ala Thr Val Asp Gln Arg
1 5 10
<210> 6560
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6560
Met Gly Leu Ile Gln Thr Ala Asp Gln Leu Arg
1 5 10
<210> 6561
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6561
Met Met Asn Gly Gly His Tyr Thr Tyr Ser Glu Asn Arg
1 5 10
<210> 6562
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6562
Met Tyr Ala Pro Ala Trp Val Ala Pro Glu Ala Leu Gln Lys
1 5 10
<210> 6563
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6563
Asn Ala Ala Glu Ala Met Leu Leu Gln Leu Gly Tyr Lys
1 5 10
<210> 6564
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6564
Asn Asp Ala Ser His Leu Leu Val Phe Thr Thr Asp Ala Lys
1 5 10
<210> 6565
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6565
Asn Gly Val Ala Pro Gly Ala Gln Ile Leu Ser Ile Lys
1 5 10
<210> 6566
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6566
Asn His Glu Glu Phe Phe Ser Asn Met Asp Cys Thr Gln Glu Glu Lys
1 5 10 15
<210> 6567
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6567
Asn Leu Asp Ser Thr Thr Val Ala Val His Gly Glu Glu Ile Tyr Cys
1 5 10 15
Lys
<210> 6568
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6568
Asn Pro Glu Gln Glu Pro Ile Pro Ile Val Leu Arg
1 5 10
<210> 6569
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6569
Asn Ser Thr Ile Val Phe Pro Leu Pro Ile Asp Met Leu Gln Gly Ile
1 5 10 15
Ile Gly Ala Lys
20
<210> 6570
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6570
Asn Ser Val Ser Gln Ile Ser Val Leu Ser Gly Gly Lys
1 5 10
<210> 6571
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6571
Asn Val Thr Glu Leu Asn Glu Pro Leu Ser Asn Glu Glu Arg
1 5 10
<210> 6572
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6572
Gln Asp His Leu Ser Trp Glu Trp Asn Leu Ser Ile Lys
1 5 10
<210> 6573
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6573
Gln Phe Ser Glu Gln Gly Leu Asp Pro Ile Asp Gly Ala Met Asn Ile
1 5 10 15
Glu Lys
<210> 6574
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6574
Gln Gly Gln Asp Ala Ile Pro Pro Pro Asp Pro Gly Glu Gln Ile Phe
1 5 10 15
Asn Leu Pro Lys
20
<210> 6575
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6575
Gln Ile Asp Leu Ser Thr Val Asp Leu Lys
1 5 10
<210> 6576
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6576
Gln Leu Glu Glu Asp Leu Tyr Asp Gly Gln Val Leu Gln Lys
1 5 10
<210> 6577
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6577
Gln Leu Glu Leu Glu Asn Leu Thr Thr Gln Glu Thr Arg
1 5 10
<210> 6578
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6578
Gln Leu Ile Leu Pro Ala Leu Gly Ser Gly Lys
1 5 10
<210> 6579
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6579
Gln Leu Leu Cys Thr Asn Glu Asp Val Ser Ser Pro Ala Ser Ala Asp
1 5 10 15
Gln Arg
<210> 6580
<211> 19
<212> PRT
<213> Homo sapiens
<400> 6580
Gln Asn Gly Glu Glu Gly Tyr Val Pro Thr Ser Tyr Ile Asp Val Thr
1 5 10 15
Leu Glu Lys
<210> 6581
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6581
Gln Gln Asp Val Leu Gly Phe Leu Glu Ala Asn Lys
1 5 10
<210> 6582
<211> 6
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
peptide"
<220>
<221> MOD_RES
<222> (1)..(1)
<223> Deamidated
<400> 6582
Gln Gln Leu Asn Leu Arg
1 5
<210> 6583
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6583
Ser Ala Ser Thr Asp Leu Gly Thr Ala Asp Val Val Leu Gly Arg
1 5 10 15
<210> 6584
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6584
Ser Cys Phe Leu Cys Met Val Cys Lys
1 5
<210> 6585
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6585
Ser Gly Phe Glu Pro Pro Gly Asp Phe Pro Phe Glu Asp Tyr Ser Gln
1 5 10 15
His Ile Tyr Arg
20
<210> 6586
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6586
Ser Gly Lys Pro Ile Leu Glu Gly Ala Ala Leu Asp Glu Ala Leu Lys
1 5 10 15
<210> 6587
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6587
Ser Gly Ser Trp Ala Ala Ile Tyr Gln Asp Ile Arg
1 5 10
<210> 6588
<211> 22
<212> PRT
<213> Homo sapiens
<400> 6588
Ser Gly Tyr His Gln Ser Ala Ser Glu His Gly Leu Val Val Ile Ala
1 5 10 15
Pro Asp Thr Ser Pro Arg
20
<210> 6589
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6589
Ser Leu Ala Thr Val His Pro Asp Ser Ser Asn Leu Ile Pro Lys
1 5 10 15
<210> 6590
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6590
Ser Leu Met Ala Ser Glu Glu Glu Tyr Ser Thr Lys
1 5 10
<210> 6591
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6591
Ser Ser Glu Asp Pro Asn Glu Asp Ile Val Glu Arg
1 5 10
<210> 6592
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6592
Ser Thr Cys Thr Tyr Val Gly Ala Ala Lys
1 5 10
<210> 6593
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6593
Ser Thr Ile Gly Gly Gln Ile Met Tyr Leu Thr Gly Met Val Asp Lys
1 5 10 15
<210> 6594
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6594
Ser Val Met Ile Asp Glu Asp Met Thr Ala Arg
1 5 10
<210> 6595
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6595
Ser Tyr Glu Leu Pro Asp Gly Gln Val Ile Thr Ile Gly Asn Glu Arg
1 5 10 15
<210> 6596
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6596
Ser Tyr Pro Gly Ser Gln Leu Asp Ile Leu Ile Asp Gln Gly Lys
1 5 10 15
<210> 6597
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6597
Thr Ala Thr Val Ser Ser Pro Leu Thr Ser Pro Thr Ser Pro Ser Thr
1 5 10 15
Leu Ser Leu Lys
20
<210> 6598
<211> 22
<212> PRT
<213> Homo sapiens
<400> 6598
Thr Glu Gly Asn Ile Phe Asp Ser Leu Ile Gly Gly Asn Ala Ser Ala
1 5 10 15
Glu Gly Pro Glu Gly Lys
20
<210> 6599
<211> 6
<212> PRT
<213> Homo sapiens
<400> 6599
Thr Glu Thr Gln Glu Lys
1 5
<210> 6600
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6600
Thr Phe Asp Ala Gln Ile Val Ile Ile Glu His Lys
1 5 10
<210> 6601
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6601
Thr Gly Leu Phe Thr Pro Asp Met Ala Phe Glu Ala Ile Val Lys
1 5 10 15
<210> 6602
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6602
Thr Gln Ile Ala Ile Cys Pro Asn Asn His Glu Val His Ile Tyr Glu
1 5 10 15
Lys
<210> 6603
<211> 21
<212> PRT
<213> Homo sapiens
<400> 6603
Thr Ser Leu Asp Ser Gly Val Pro His Tyr Ser Val Thr Glu Pro Gln
1 5 10 15
Val Ala Val Asn Lys
20
<210> 6604
<211> 8
<212> PRT
<213> Homo sapiens
<400> 6604
Thr Thr Ser Gln Val Arg Pro Arg
1 5
<210> 6605
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6605
Thr Val Tyr Phe Ala Glu Glu Val Gln Cys Glu Gly Asn Ser Phe His
1 5 10 15
Lys
<210> 6606
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6606
Val Ala Ala Tyr Phe Gly Met Asp His Asn Val Asp Gln Thr Gly Lys
1 5 10 15
<210> 6607
<211> 20
<212> PRT
<213> Homo sapiens
<400> 6607
Val Ala Ser Met Ala Gln Ser Ala Pro Ser Glu Ala Pro Ser Cys Ser
1 5 10 15
Pro Phe Gly Lys
20
<210> 6608
<211> 10
<212> PRT
<213> Homo sapiens
<400> 6608
Val Asp Asp Gln Ile Ala Ile Val Phe Lys
1 5 10
<210> 6609
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6609
Val Asp Phe Glu Thr Phe Leu Pro Met Leu Gln Ala Val Ala Lys
1 5 10 15
<210> 6610
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6610
Val Glu Ile Leu Cys Glu His Pro Arg
1 5
<210> 6611
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6611
Val His Leu Ser Phe Gly Leu Asp Cys Pro Ile Leu Gly Asp His Lys
1 5 10 15
<210> 6612
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6612
Val Ile Ala Ala Glu Gly Glu Met Asn Ala Ser Arg
1 5 10
<210> 6613
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6613
Val Ile Ser Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys
1 5 10
<210> 6614
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6614
Val Lys Pro Phe Met Thr Gly Ala Ala Glu Gln Ile Lys
1 5 10
<210> 6615
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6615
Val Leu Glu Val Thr Asp Leu Pro Glu Gly Ile Thr Arg
1 5 10
<210> 6616
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6616
Val Leu Leu Asp Trp Ile Asn Asp Val Leu Val Glu Glu Arg
1 5 10
<210> 6617
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6617
Val Leu Pro Gly Val Asp Ala Leu Ser Asn Ile
1 5 10
<210> 6618
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6618
Val Pro Asp Asp Pro Glu His Leu Ala Ala Arg
1 5 10
<210> 6619
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6619
Val Pro Thr Ala Asn Val Ser Val Val Asp Leu Thr Cys Arg
1 5 10
<210> 6620
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6620
Val Pro Val Gly Asp Gln Pro Pro Asp Ile Glu Tyr Gln Ile Arg
1 5 10 15
<210> 6621
<211> 18
<212> PRT
<213> Homo sapiens
<400> 6621
Val Arg Gly Thr Asp Pro Val Ser Thr Val Thr Leu Ser Leu Leu Glu
1 5 10 15
Pro Glu
<210> 6622
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6622
Val Ser Glu Asp Asp Glu Thr Gln Pro Glu Lys
1 5 10
<210> 6623
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6623
Val Ser Leu Val Leu Ala Pro Ala Leu Ala Ala Cys Gly Cys Lys
1 5 10 15
<210> 6624
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6624
Val Ser Ser Gly Tyr Val Pro Pro Pro Val Ala Thr Pro Phe Ser Ser
1 5 10 15
Lys
<210> 6625
<211> 15
<212> PRT
<213> Homo sapiens
<400> 6625
Val Ser Val Gly Glu Phe Ser Ala Glu Gly Glu Gly Asn Ser Lys
1 5 10 15
<210> 6626
<211> 12
<212> PRT
<213> Homo sapiens
<400> 6626
Val Val Leu Glu Gly Pro Ala Pro Trp Gly Phe Arg
1 5 10
<210> 6627
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6627
Val Tyr Ile Ala Ser Ser Ser Gly Ser Thr Ala Ile Lys
1 5 10
<210> 6628
<211> 21
<212> PRT
<213> Homo sapiens
<400> 6628
Trp Gly Asp Ala Gly Ala Glu Tyr Val Val Glu Ser Thr Gly Val Phe
1 5 10 15
Thr Thr Met Glu Lys
20
<210> 6629
<211> 7
<212> PRT
<213> Homo sapiens
<400> 6629
Trp His Ser Leu Ile Ala Lys
1 5
<210> 6630
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6630
Trp Ser Ala Ser Gly Pro Trp Ile Arg
1 5
<210> 6631
<211> 13
<212> PRT
<213> Homo sapiens
<400> 6631
Trp Ser Thr Leu Val Glu Asp Tyr Gly Met Glu Leu Arg
1 5 10
<210> 6632
<211> 9
<212> PRT
<213> Homo sapiens
<400> 6632
Tyr Ala Gly Gly Val Ala Glu Tyr Arg
1 5
<210> 6633
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6633
Tyr Ala Gly Leu Lys Pro Gly Glu Leu Pro Thr Cys Glu Ser Leu Lys
1 5 10 15
<210> 6634
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6634
Tyr Glu Asp Ile Cys Pro Ser Thr His Asn Met Asp Val Pro Asn Ile
1 5 10 15
Lys
<210> 6635
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6635
Tyr Glu Gly Ser Tyr Ala Leu Thr Ser Glu Glu Ala Glu Arg
1 5 10
<210> 6636
<211> 17
<212> PRT
<213> Homo sapiens
<400> 6636
Tyr Leu Ser Gln Glu Glu Gln Ser Thr Ala Ala Leu Thr Leu Tyr Thr
1 5 10 15
Lys
<210> 6637
<211> 16
<212> PRT
<213> Homo sapiens
<400> 6637
Tyr Pro Ile Glu His Gly Ile Val Thr Asn Trp Asp Asp Met Glu Lys
1 5 10 15
<210> 6638
<211> 11
<212> PRT
<213> Homo sapiens
<400> 6638
Tyr Thr Phe Ala Pro Ser Val Ser Leu Asn Lys
1 5 10
<210> 6639
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6639
Tyr Val Leu Asp Asp Glu Tyr Thr Ser Ser Val Gly Ser Lys
1 5 10
<210> 6640
<211> 14
<212> PRT
<213> Homo sapiens
<400> 6640
Tyr Tyr Thr Ser Ala Ser Gly Asp Glu Met Val Ser Leu Lys
1 5 10
<210> 6641
<211> 15
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
heavy-isotope-labeled peptide"
<400> 6641
Thr Gly Glu Gly Phe Leu Cys Val Phe Ala Ile Asn Asn Thr Lys
1 5 10 15
<210> 6642
<211> 9
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
heavy-isotope-labeled peptide"
<400> 6642
Ser Phe Glu Asp Ile His His Tyr Arg
1 5
<210> 6643
<211> 13
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
heavy-isotope-labeled peptide"
<400> 6643
Asp Ser Glu Asp Val Pro Met Val Leu Val Gly Asn Lys
1 5 10
<210> 6644
<211> 12
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
heavy-isotope-labeled peptide"
<400> 6644
Ser Tyr Gly Ile Pro Phe Ile Glu Thr Ser Ala Lys
1 5 10
<210> 6645
<211> 10
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
heavy-isotope-labeled peptide"
<400> 6645
Val Glu Asp Ala Phe Tyr Thr Leu Val Arg
1 5 10
<210> 6646
<211> 11
<212> PRT
<213> Artificial Sequence
<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
heavy-isotope-labeled peptide"
<400> 6646
Leu Val Val Val Gly Ala Asp Gly Val Gly Lys
1 5 10
Claims (25)
- 난소암을 치료하기 위한 방법에 있어서, 상기 방법은
포유동물로부터 획득된 혈액 표본 내에 펩티딜-프로릴 시스-트랜스 이성화효소 A (PPIA) 폴리펩티드로부터 유래된 펩티드 단편을 포함하는 상승된 수준의 하나 또는 그 이상의 펩티드 생물마커를 검출하는 단계, 그리고
한 가지 또는 그 이상의 암 치료를 상기 포유동물에게 투여하는 단계를 포함하는, 방법 - 청구항 제 1항에 있어서, 상기 한 가지 또는 그 이상의 암 치료는 수술, 화학요법, 호르몬 요법, 표적화된 요법, 방사선요법, 그리고 이들의 조합으로 구성된 군에서 선택되는, 방법.
- 포유동물이 난소암을 겪는 것으로 확인하기 위한 방법에 있어서, 상기 방법은
상기 포유동물로부터 획득된 혈액 표본 내에 펩티딜-프로릴 시스-트랜스 이성화효소 A (PPIA) 폴리펩티드로부터 유래된 펩티드 단편을 포함하는 하나 또는 그 이상의 혈액 펩티드 생물마커의 수준을 검출하는 단계, 그리고
상승된 수준의 하나 또는 그 이상의 혈액 펩티드 생물마커가 상기 혈액 표본에서 검출될 때, 상기 포유동물이 난소암을 겪는 것으로 진단하는 단계를 포함하는, 방법. - 청구항 제 1항 내지 제 3항 중 어느 한 항에 있어서, 상기 포유동물은 인간인, 방법.
- 청구항 제 1항 내지 제 4항 중 어느 한 항에 있어서, 상기 혈액 표본은 혈장 표본인, 방법.
- 청구항 제 1항 내지 제 5항 중 어느 한 항에 있어서, 상기 PPIA 펩티드 단편은 아미노산 서열 VSFELFADK (서열 번호: 1)를 포함하는, 방법.
- 청구항 제 1항 내지 제 5항 중 어느 한 항에 있어서, 상기 PPIA 펩티드 단편은 아미노산 서열 FEDENFILK (서열 번호: 2)를 포함하는, 방법.
- 펩티드 생물마커를 확인하기 위한 방법에 있어서, 상기 방법은
질환 혈액 표본 내에 존재하는 폴리펩티드를 소화시켜 질환 펩티드 단편을 획득하는 단계;
상기 질환 펩티드 단편을 첫 번째 중동위원소로 표지화하여 표지화된 질환 펩티드 단편을 획득하는 단계;
참조 혈액 표본 내에 존재하는 폴리펩티드를 소화시켜 참조 펩티드 단편을 획득하는 단계;
상기 참조 펩티드 단편을 두 번째 중동위원소로 표지화하여 표지화된 참조 펩티드 단편을 획득하는 단계;
표지화된 질환 펩티드 단편 및 표지화된 참조 펩티드 단편을 질량 분광분석법에 종속시켜 펩티드 생물마커를 확인하는 단계를 포함하고, 여기서 상기 펩티드 생물마커의 수준은 표지화된 참조 펩티드 단편에 비하여 표지화된 질환 펩티드 단편에서 상승되는, 방법. - 청구항 제 8항에 있어서, 상기 질환 혈액 표본은 상기 질환을 겪는 한 마리 또는 그 이상의 포유동물로부터 획득된 혈액을 포함하는, 방법.
- 청구항 제 9항에 있어서, 상기 질환 혈액 표본은 상기 질환을 겪는 복수의 포유동물로부터 획득된 혈액을 포함하는, 방법.
- 청구항 제 8항 내지 제 10항 중 어느 한 항에 있어서, 상기 참조 혈액 표본은 한 마리 또는 그 이상의 건강한 포유동물로부터 획득된 혈액을 포함하는, 방법.
- 청구항 제 11항에 있어서, 상기 참조 혈액 표본은 복수의 건강한 포유동물로부터 획득된 혈액을 포함하는, 방법.
- 청구항 제 8항 내지 제 12항 중 어느 한 항에 있어서, 상기 방법은 각 표본으로부터 한 가지 또는 그 이상의 매우 풍부한 혈액 단백질을 고갈시키는 단계를 더욱 포함하는, 방법.
- 청구항 제 13항에 있어서, 상기 매우 풍부한 혈액 단백질은 알부민, IgG, α1-항트립신, IgA, IgM, 트랜스페린, 합토글로빈, α2-마크로글로불린, 피브리노겐, 보체 C3, α1-산 당단백질, 아포지질단백질 A-I, 아포지질단백질 A-II, 아포지질단백질 B, 그리고 이들의 조합으로 구성된 군에서 선택되는, 방법.
- 청구항 제 8항 내지 제 14항 중 어느 한 항에 있어서, 상기 방법은 각 소화 단계에 앞서, 각 표본에서 당단백질을 농축하는 단계를 더욱 포함하는, 방법.
- 청구항 제 8항 내지 제 15항 중 어느 한 항에 있어서, 상기 질량 분광분석법은 Orbitrap 질량분광계를 이용하여 수행되는, 방법.
- 펩티드 생물마커를 검증하기 위한 방법에 있어서, 상기 방법은
상기 펩티드 생물마커를 포함하는 복수의 펩티드를 염기성 pH 역상 액체 크로마토그래피 (bRPLC)에 종속시켜 복수의 분획물을 획득하는 단계;
상기 복수의 분획물을 복수의 분획물 군으로 조직화하되, 분획물의 숫자가 분획물 군의 숫자보다 많은 단계;
각 분획물 군에서 펩티드 생물마커를 산성 pH에서 직교 고성능 액체 크로마토그래피 (HPLC)에 의해 분리하여 연속 HPLC 용리액을 획득하는 단계; 그리고
상기 펩티드 생물마커에 대한 미리 최적화된 트랜지션 및 미리 최적화된 체류 시간을 포함하는 선별된 반응 모니터링 (SRM) 방법을 이용하여 상기 연속 HPLC 용리액을 분석하여, 상기 펩티드 생물마커의 강도를 결정하는 단계를 포함하고;
여기서 펩티드 생물마커는 이러한 펩티드 생물마커가 상기 SRM 방법을 이용하여, 참조 표본에 비하여 질환 표본에서 상승된 수준에서 검출되고 정량될 때 검증되는, 방법. - 펩티드 생물마커를 확인하고 검증하기 위한 방법에 있어서, 상기 방법은 하기를 포함하고:
A. 후보 펩티드 생물마커의 확인, 여기서 상기 확인은
i 질환 혈액 표본 내에 존재하는 폴리펩티드를 소화시켜 질환 펩티드 단편을 획득하는 단계;
ii. 상기 질환 펩티드 단편을 첫 번째 중동위원소로 표지화하여 표지화된 질환 펩티드 단편을 획득하는 단계;
iii. 참조 혈액 표본 내에 존재하는 폴리펩티드를 소화시켜 참조 펩티드 단편을 획득하는 단계;
iv. 상기 참조 펩티드 단편을 두 번째 중동위원소로 표지화하여 표지화된 참조 펩티드 단편을 획득하는 단계;
v. 표지화된 질환 펩티드 단편 및 표지화된 참조 펩티드 단편을 질량 분광분석법에 종속시켜 후보 펩티드 생물마커를 확인하는 단계를 포함하고, 여기서 상기 후보 펩티드 생물마커의 수준은 표지화된 참조 펩티드 단편에 비하여 표지화된 질환 펩티드 단편에서 상승되고;
B. SAFE-SRM 방법의 구축, 여기서 상기 구축은
i. 상기 후보 펩티드 생물마커를 합성하는 단계;
ii. 상기 합성 후보 펩티드 생물마커를 질량 분광분석법에 종속시켜 후보 펩티드 생물마커 트랜지션을 결정하되, 상기 트랜지션이 가장 강한 강도를 갖는 선구 이온-생성 이온 쌍을 확인하고 상기 선구 이온-생성 이온 쌍을 생산하는 충돌 에너지 (CE)를 확인함으로써 결정되는 단계;
iii. 상기 후보 펩티드 생물마커를 포함하는 복수의 펩티드를 염기성 pH 역상 액체 크로마토그래피 (bRPLC)에 종속시켜 복수의 분획물을 획득하되, 상기 복수의 분획물이 본질적으로 동등한 양의 각 펩티드로 구성되는 단계;
iv. 상기 복수의 분획물을 복수의 분획물 군으로 조직화하되, 분획물의 숫자가 분획물 군의 숫자보다 많은 단계;
v. 후보 펩티드 생물마커 트랜지션 및 고정된 체류 시간을 이용하여, 상기 분획물 군 각각에서 상기 후보 펩티드 생물마커의 강도를 결정하는 단계; 그리고
vi. 이들 트랜지션을 높은 pH에서 그들의 소수성에 따라서 재조립함으로써 체류 시간을 최적화하는 단계를 포함하고; 그리고
C. 상기 후보 펩티드 생물마커의 검증, 여기서 상기 검증은
i. 상기 질환 혈액 표본에서 상기 후보 펩티드 생물마커를 정량하되, 상기 정량이
a. 상기 후보 펩티드 생물마커를 포함하는 상기 질환 펩티드 단편을 bRPLC에 종속시켜 복수의 분획물을 획득하고;
b. 상기 복수의 분획물을 복수의 분획물 군으로 조직화하고, 여기서 분획물의 숫자가 분획물 군의 숫자보다 많고;
c. 각 분획물 군에서 펩티드를 산성 pH에서 직교 HPLC에 의해 분리하여 연속 HPLC 용리액을 획득하고; 그리고
d. 상기 후보 펩티드 생물마커 트랜지션 및 상기 최적화된 체류 시간을 포함하는 SRM 방법을 이용하여 상기 연속 HPLC 용리액을 분석하는 것을 포함하는 단계; 그리고
ii. 상기 참조 혈액 표본에서 상기 후보 펩티드 마커를 정량하되, 상기 정량이
a. 상기 참조 펩티드 단편을 bRPLC에 종속시켜 복수의 분획물을 획득하고;
b. 상기 복수의 분획물을 복수의 분획물 군으로 조직화하고, 여기서 분획물의 숫자가 분획물 군의 숫자보다 많고;
c. 각 분획물 군에서 펩티드를 산성 pH에서 직교 HPLC에 의해 분리하여 연속 HPLC 용리액을 획득하고;
d. 상기 후보 펩티드 생물마커 트랜지션 및 상기 최적화된 체류 시간을 포함하는 상기 SRM 방법을 이용하여 상기 연속 HPLC 용리액을 분석하는 것을 포함하는 단계; 그리고
iii. 후보 펩티드 생물마커가 상기 참조 표본에 비하여 상기 질환 표본에서 상승된 수준에서 정량될 때, 상기 후보 펩티드 생물마커를 검증하는 단계를 포함하는, 방법. - 청구항 제 18항에 있어서, 상기 합성된 후보 펩티드 생물마커는 중동위원소로 표지화되지 않는, 방법.
- 청구항 제 19항에 있어서, 펩티드 생물마커에 대한 최적화된 체류 시간은 개체로부터 획득된 표본 내에 존재하는 스파이킹된 합성 생물마커 펩티드를 이용하여 결정되는, 방법.
- 청구항 제 17항 내지 제 20항 중 어느 한 항에 있어서, 펩티드 생물마커에 대한 상기 최적화된 체류 시간은 이러한 펩티드 생물마커의 강도에 역비례하는, 방법.
- 청구항 제 17항 내지 제 21항 중 어느 한 항에 있어서, 상기 HPLC는 질량분광계에 연계되는 장치로 수행되는, 방법.
- 청구항 제 22항에 있어서, 상기 질량분광계는 삼중 4극 질량분광계인, 방법.
- 청구항 제 17항 내지 제 23항 중 어느 한 항에 있어서, 충돌 에너지는 데이터세트 S5에서 진술된 충돌 에너지 중에서 한 가지인, 방법.
- 청구항 제 17항 내지 제 23항 중 어느 한 항에 있어서, 체류 시간은 데이터세트 S5에서 진술된 체류 시간 중에서 한 가지인, 방법.
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| CA2487314A1 (en) * | 2002-06-03 | 2003-12-11 | The Institute For Systems Biology | Methods for quantitative proteome analysis of glycoproteins |
| KR20070049637A (ko) * | 2004-07-09 | 2007-05-11 | 트리패스 이미징, 인코포레이티드 | 난소 질환 검출 방법 및 조성물 |
| WO2009075883A2 (en) * | 2007-12-12 | 2009-06-18 | University Of Georgia Research Foundation, Inc. | Glycoprotein cancer biomarker |
| WO2009124403A1 (en) | 2008-04-10 | 2009-10-15 | The University Of British Columbia | Methods of diagnosing chronic cardiac allograft rejection |
| US9796761B2 (en) * | 2009-07-14 | 2017-10-24 | National Institute Of Advanced Industrial Science And Technology | Glycan markers as measure of disease state of hepatic diseases |
| WO2013019634A1 (en) * | 2011-07-29 | 2013-02-07 | University Of Georgia Research Foundation, Inc. | Alpha toxin detection of gpi anchored proteins |
| JP6082026B2 (ja) | 2011-12-21 | 2017-02-15 | インテグレイティド ダイアグノスティクス，インコーポレイティド | 肺癌診断用の組成物、方法及びキット |
| JP2016029335A (ja) * | 2012-12-17 | 2016-03-03 | 国立研究開発法人医薬基盤・健康・栄養研究所 | 大腸がんの判定方法 |
| WO2014210031A1 (en) | 2013-06-25 | 2014-12-31 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Proteomic biomarkers of sepsis in elderly patients |
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2018
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- 2018-11-20 KR KR1020207017422A patent/KR20200100644A/ko not_active Application Discontinuation
- 2018-11-20 AU AU2018370339A patent/AU2018370339A1/en active Pending
- 2018-11-20 US US16/765,343 patent/US20210063401A1/en not_active Abandoned
- 2018-11-20 CN CN201880087156.4A patent/CN111630385A/zh active Pending
- 2018-11-20 EP EP18825819.8A patent/EP3714272A1/en active Pending
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- 2018-11-20 WO PCT/US2018/062007 patent/WO2019100059A1/en unknown
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2020
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| WO2019100059A1 (en) | 2019-05-23 |
| US20210063401A1 (en) | 2021-03-04 |
| CN111630385A (zh) | 2020-09-04 |
| CA3083018A1 (en) | 2019-05-23 |
| JP2021503607A (ja) | 2021-02-12 |
| AU2018370339A1 (en) | 2020-06-04 |
| IL274714A (en) | 2020-07-30 |
| JP7312464B2 (ja) | 2023-07-21 |
| EP3714272A1 (en) | 2020-09-30 |
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