KR20200080439A - A Medicated Plaster for Treating Rheumatism - Google Patents
A Medicated Plaster for Treating Rheumatism Download PDFInfo
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- KR20200080439A KR20200080439A KR1020180169028A KR20180169028A KR20200080439A KR 20200080439 A KR20200080439 A KR 20200080439A KR 1020180169028 A KR1020180169028 A KR 1020180169028A KR 20180169028 A KR20180169028 A KR 20180169028A KR 20200080439 A KR20200080439 A KR 20200080439A
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- 239000011505 plaster Substances 0.000 title claims abstract description 44
- 239000003814 drug Substances 0.000 claims abstract description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 235000006679 Mentha X verticillata Nutrition 0.000 claims abstract description 9
- 235000002899 Mentha suaveolens Nutrition 0.000 claims abstract description 9
- 235000001636 Mentha x rotundifolia Nutrition 0.000 claims abstract description 9
- 239000000203 mixture Substances 0.000 claims abstract description 8
- 238000001816 cooling Methods 0.000 claims abstract description 4
- 238000011282 treatment Methods 0.000 claims description 38
- 239000002994 raw material Substances 0.000 claims description 8
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 claims description 7
- 244000035851 Chrysanthemum leucanthemum Species 0.000 claims description 7
- 240000002817 Leonurus sibiricus Species 0.000 claims description 3
- 239000004744 fabric Substances 0.000 claims description 3
- 238000010257 thawing Methods 0.000 claims description 3
- 235000012907 honey Nutrition 0.000 claims 3
- 244000118350 Andrographis paniculata Species 0.000 abstract description 2
- 240000002853 Nelumbo nucifera Species 0.000 abstract description 2
- 235000006508 Nelumbo nucifera Nutrition 0.000 abstract description 2
- 241000721329 Chrysanthemum boreale Species 0.000 abstract 1
- 235000008642 Chrysanthemum boreale Nutrition 0.000 abstract 1
- 241001317551 Prunella asiatica Species 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 238000010298 pulverizing process Methods 0.000 abstract 1
- 239000002759 woven fabric Substances 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 description 27
- 230000000694 effects Effects 0.000 description 19
- 208000024891 symptom Diseases 0.000 description 14
- 241000411851 herbal medicine Species 0.000 description 6
- 210000003205 muscle Anatomy 0.000 description 6
- 229940079593 drug Drugs 0.000 description 5
- 208000025747 Rheumatic disease Diseases 0.000 description 4
- 230000000552 rheumatic effect Effects 0.000 description 4
- 210000001503 joint Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- 230000002195 synergetic effect Effects 0.000 description 3
- 208000008035 Back Pain Diseases 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000011514 reflex Effects 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 229940124594 traditional oriental medicine Drugs 0.000 description 2
- 208000006820 Arthralgia Diseases 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000016285 Movement disease Diseases 0.000 description 1
- 206010028391 Musculoskeletal Pain Diseases 0.000 description 1
- 206010028836 Neck pain Diseases 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 244000179560 Prunella vulgaris Species 0.000 description 1
- 235000010674 Prunella vulgaris Nutrition 0.000 description 1
- 208000007613 Shoulder Pain Diseases 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 238000004378 air conditioning Methods 0.000 description 1
- 239000002269 analeptic agent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000010339 dilation Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 210000003195 fascia Anatomy 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 210000003041 ligament Anatomy 0.000 description 1
- 230000008338 local blood flow Effects 0.000 description 1
- 210000001365 lymphatic vessel Anatomy 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000001640 nerve ending Anatomy 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 231100000956 nontoxicity Toxicity 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 208000027753 pain disease Diseases 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000037368 penetrate the skin Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000001839 systemic circulation Effects 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 230000010415 tropism Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
본 발명은 한방 약제 분야에 관한 것이며, 특히 류머티즘 치료용 약제 플라스터에 관한 것이다.The present invention relates to the field of herbal medicine, and in particular to a pharmaceutical plaster for the treatment of rheumatism.
류머티즘성 통증은 주로 관절 주위의 연조직(근육 건(muscle tendon), 인대(ligament), 점액성 윤활주머니(mucous bursae), 근막(fascia) 등), 근육, 뼈, 및 관절에 발병하는 질환에 의해 야기되는 국소적 또는 전신적 통증을 일컫는다. 상기 류머티즘성 통증 질환은, 전통 한의학 분야에서 풍성 병원성 요인(windiness pathogenic factor) 및 습성 병원성 요인(wetness pathogenic factor)의 조합에 의해 야기되는 것으로 여겨지는 일종의 마비(paralysis)이다. 통증 뿐만 아니라, 관절 병변(joint lesion)에는 발작 및 완화를 교대(alternation)로 하는 만성적인 경과를 보이는, 부기 및 운동 장애가 동반된다. 환자의 혈액 순환이 원활하지 않기 때문에, 근육 또는 조직에 필요한 영양소가 혈액 순환을 통해 수송될 수 없어, 환자의 근육에 영양소 부족을 야기함으로써, 근육의 노화를 가속화하고 근육을 경직시킨다.Rheumatoid pain is mainly caused by diseases that affect the soft tissues around the joints (muscle tendon, ligament, mucous bursae, fascia, etc.), muscles, bones, and joints. Refers to local or systemic pain caused. The rheumatic pain disease is a kind of paralysis considered to be caused by a combination of a windiness pathogenic factor and a wetness pathogenic factor in the traditional oriental medicine field. In addition to pain, joint lesions are accompanied by swelling and movement disorders, with a chronic course of alternating seizures and relief. Because the patient's blood circulation is not smooth, the nutrients needed by the muscles or tissues cannot be transported through the blood circulation, causing the patient's muscles to lack nutrients, accelerating aging of the muscles and stiffening the muscles.
류머티즘 치료용 약제 플라스터가 피부를 통해 작용하는 류머티즘 치료용 약제 플라스터 적용 치료법은, 전통 한의학 임상 적용에서 일반적으로 사용되는 외용 치료법 중 하나이며; 상기 류머티즘 치료용 약제 플라스터 적용 치료법은 한방 약제에서의 변증(syndrome differentiation) 및 치료의 원리와, 한방 약제의 효능, 적응증(indication) 및 채널 트로피즘(channel tropism)을 따르고; 이에 따라 상기 류머티즘 치료용 약제 플라스터 적용 치료법은 모든 한방 약제 원료의 시너지 효과를 충분히 발휘하여 다중-약제 화합물 처방을 제공함으로써, 좋은 의학적 효과를 달성한다. 상기 류머티즘 치료용 약제 플라스터는 신체 표면 상에 직접적으로 적용되며, 류머티즘 치료용 약제 플라스터를 만드는데 사용되는 약용 원료의 대부분은 냄새가 진하고, 향이 향기롭고 이동성이 높은 채널 인도성 약제(channel-ushering medicine)가 추가적으로 사용되므로, 그들은 피부 내에 침투하고 경락(meridian) 및 장기(viscera)에 들어가, 기(Qi) 및 혈액을 조절하고, 경락을 훑고(dredge), 냉습(cold-dampness)을 없애며, 부기 및 통증을 완화시키는 등의 효과를 달성한다.The pharmaceutical plaster application treatment method for rheumatism treatment, in which the pharmaceutical plaster for rheumatism acts through the skin, is one of the external treatments generally used in traditional oriental medicine clinical applications; The rheumatism treatment drug plaster application treatment method follows the principle of syndrome differentiation and treatment in herbal medicine, and the efficacy, indication and channel tropism of herbal medicine; Accordingly, the treatment method for applying pharmaceutical plaster for rheumatism treatment sufficiently exerts a synergistic effect of all herbal medicine raw materials to provide a multi-drug compound prescription, thereby achieving a good medical effect. The rheumatism treatment drug plaster is applied directly on the surface of the body, and most of the medicinal raw materials used to make the rheumatism treatment medicine plaster have a strong odor, fragrant fragrance, and high mobility channel-ushering medicine. As it is additionally used, they penetrate the skin and enter the meridians and visceras, regulating Qi and blood, dredge, eliminate cold-dampness, swelling and pain To achieve the effect, such as to ease.
신체 표면에 적용되는 상기 류머티즘 치료용 약제 플라스터는 신경 말단을 자극하고 신경 반사를 야기하여, 결과적으로 혈관을 확장시키고, 국소적인 혈액순환을 촉진하며, 주변 조직의 영양을 개선하여, 부기 및 염증을 감소시키고 통증을 완화시키는 목적을 달성한다. 동시에, 약제는 작용 부위에서 피부를 통해 피하조직을 관통하고, 국소적 약제 농축의 상대적인 이점을 발생시킴으로써, 강한 약리 효과를 발휘한다. 또한, 상기 류머티즘 치료용 약제 플라스터는 강한 자극을 발생시킬 수 있는 일부 강한 자극성 약제를 함유하고, 이러한 강한 자극은 신경 반사를 야기할 수 있어, 결과적으로 인체의 기능을 조절하고, 항체의 형성을 촉진하며, 인간의 면역을 개선한다. 상기 약제 플라스터 내의 약제는, 피부 및 점막을 관통한 후, 혈관 또는 림프관을 통하여 체순환(systemic circulation)에 들어가, 전신성(systemic) 약효를 발휘한다.The pharmaceutical plaster for the treatment of rheumatism applied to the surface of the body stimulates the nerve endings and causes nerve reflex, resulting in dilation of blood vessels, promoting local blood circulation, improving nutrition of surrounding tissues, reducing swelling and inflammation And achieve the purpose of alleviating pain. At the same time, the drug exerts a strong pharmacological effect by penetrating the subcutaneous tissue through the skin at the site of action and generating the relative advantage of local drug concentration. In addition, the pharmaceutical plaster for the treatment of rheumatism contains some strong stimulant agents capable of generating strong stimuli, and such strong stimuli may cause neural reflexes, consequently regulating the function of the human body and promoting the formation of antibodies And improve human immunity. The medicine in the medicine plaster, after penetrating the skin and mucous membrane, enters a systemic circulation through a blood vessel or a lymphatic vessel, and exerts a systemic effect.
종래 기술에서는, 효과가 빠르고 안정적이며 부작용이 적은 류머티즘 치료용 약제 플라스터가 부족하다.In the prior art, there is a shortage of pharmaceutical plasters for the treatment of rheumatism with fast, stable and low side effects.
본 발명의 목적은 상기 종래 기술의 단점을 극복하고, 효과가 빠르고 안정적이며 부작용이 적고 류머티즘성 통증을 완화시킬 수 있는 류머티즘 치료용 약제 플라스터를 제공하는 것이다.An object of the present invention is to provide a pharmaceutical plaster for rheumatism treatment that overcomes the disadvantages of the prior art, has a fast and stable effect, has fewer side effects, and can relieve rheumatic pain.
이러한 목적을 위해, 본 발명은 For this purpose, the present invention
연자심(Lotus Plumule) 30 내지 40 중량부, 들국화(Wild Chrysanthemum) 20 내지 30 중량부, 천심련(Andrographis paniculata) 15 내지 20 중량부, 꿀풀(Prunella vulgaris) 10 내지 15 중량부 및 민트 오일(mint oil) 3 내지 7 중량부를 포함하는 류머티즘 치료용 약제 플라스터로서,30 to 40 parts by weight of Lotus Plumule, 20 to 30 parts by weight of Wild Chrysanthemum, 15 to 20 parts by weight of Andrographis paniculata, 10 to 15 parts by weight of Prunella vulgaris, and mint oil (mint) oil) as a pharmaceutical plaster for rheumatism treatment containing 3 to 7 parts by weight,
상기 류머티즘 치료용 약제 플라스터는The rheumatism treatment plaster is
상기 원료들 모두를 혼합하여 혼합물을 얻고, 물을 첨가하여 상기 혼합물을 갈아 페이스트를 얻는 단계; Mixing all the raw materials to obtain a mixture, and adding water to grind the mixture to obtain a paste;
상기 페이스트를 약불에서 50 내지 70분 동안 물로 달이는 단계로서, 상기 물은 페이스트의 상태를 유지하기에 적절한 양으로 존재하는 단계; 및Defrosting the paste with water for about 50 to 70 minutes on low heat, wherein the water is present in an amount suitable to maintain the state of the paste; And
상기 가열된 페이스트를 냉각하여 냉각된 페이스트 약제를 얻고, 상기 냉각된 페이스트 약제를 류머티즘 치료용 약제 플라스터 직물 상에 도포하는 단계에 의해 제조되는 것인 류머티즘 치료용 약제 플라스터를 제공한다.Provided is a pharmaceutical plaster for rheumatism treatment, which is prepared by cooling the heated paste to obtain a cooled paste medicine, and applying the cooled paste medicine on a pharmaceutical plaster fabric for rheumatism treatment.
사용시, 상기 류머티즘 치료용 약제 플라스터를 필요한 부위에 적용하기만 하여도, 다양한 류머티즘에 의해 발생하는 각 부위의 통증을 효과적으로 완화시킬 수 있다.In use, it is possible to effectively relieve pain in each part caused by various rheumatism by simply applying the pharmaceutical plaster for treating rheumatism to the necessary site.
본 발명에 의해 제공되는 류머티즘 치료용 약제 플라스터는 효과가 빠르고 안정적이며, 부작용이 적은 것 등의 이점을 갖는다.The pharmaceutical plaster for rheumatism provided by the present invention has advantages such as fast and stable effect and less side effects.
본 발명의 다른 특징 및 이점들은 하기 구체적인 실시형태들에서 자세히 설명될 것이다.Other features and advantages of the invention will be described in detail in the following specific embodiments.
본 발명은The present invention
연자심 30 내지 40 중량부, 들국화 20 내지 30 중량부, 천심련 15 내지 20 중량부, 꿀풀 10 내지 15 중량부 및 민트 오일 3 내지 7 중량부를 포함하는 류머티즘 치료용 약제 플라스터로서,As a pharmaceutical plaster for the treatment of rheumatism comprising 30 to 40 parts by weight of soft magnetic core, 20 to 30 parts by weight of wild chrysanthemum, 15 to 20 parts by weight of Cheonseom Rye, 10 to 15 parts by weight of honeyweed, and 3 to 7 parts by weight of mint oil,
상기 류머티즘 치료용 약제 플라스터는The rheumatism treatment plaster is
상기 원료들 모두를 혼합하여 혼합물을 얻고, 물을 첨가하여 상기 혼합물을 갈아 페이스트를 얻는 단계; Mixing all the raw materials to obtain a mixture, and adding water to grind the mixture to obtain a paste;
상기 페이스트를 약불에서 50 내지 70분 동안 물로 달이는 단계로서, 상기 물은 페이스트의 상태를 유지하기에 적절한 양으로 존재하는 단계; 및Defrosting the paste with water for about 50 to 70 minutes on low heat, wherein the water is present in an amount suitable to maintain the state of the paste; And
상기 가열된 페이스트를 냉각하여 냉각된 페이스트 약제를 얻고, 상기 냉각된 페이스트 약제를 류머티즘 치료용 약제 플라스터 직물 상에 도포하는 단계에 의해 제조되는 것인 류머티즘 치료용 약제 플라스터를 제공한다.Provided is a pharmaceutical plaster for rheumatism treatment, which is prepared by cooling the heated paste to obtain a cooled paste medicine, and applying the cooled paste medicine on a pharmaceutical plaster fabric for rheumatism treatment.
사용시, 상기 류머티즘 치료용 약제 플라스터를 필요한 부위에 적용하기만 하여도, 다양한 류머티즘에 의해 발생하는 각 부위의 통증을 효과적으로 완화시킬 수 있다.In use, it is possible to effectively relieve pain in each part caused by various rheumatism by simply applying the pharmaceutical plaster for treating rheumatism to the necessary site.
이하, 본 발명은 실시예들을 참조로 자세하게 설명될 것이다.Hereinafter, the present invention will be described in detail with reference to embodiments.
실시예 1 내지 5Examples 1 to 5
실시예 1 내지 5는 본 발명에 의해 제공되는 류머티즘 치료용 약제 플라스터를 설명하는 데 사용된다.Examples 1 to 5 are used to describe the pharmaceutical plaster for rheumatism treatment provided by the present invention.
실시예 1 내지 5에서, 표 1의 원료 비율에 따라 류머티즘 치료용 약제 플라스터 1 내지 5를 제조하였다.In Examples 1 to 5, pharmaceutical plasters 1 to 5 for rheumatism treatment were prepared according to the raw material ratios in Table 1.
실험예 1 내지 3Experimental Examples 1-3
실험예 1 내지 3은 본 발명에 의해 제공되는 류머티즘 치료용 약제 플라스터의 통증 완화 효과를 설명하는 데 사용된다.Experimental Examples 1 to 3 are used to explain the pain relief effect of the pharmaceutical plaster for rheumatism provided by the present invention.
(1) 류머티즘에 의해 발생하는 허리 통증의 완화(1) Relief of back pain caused by rheumatism
서로 다른 강도의 허리 류머티즘성 통증 증상을 겪고 있는 (25 내지 40세의) 150명의 남성 또는 여성 실험자를 선택하고, 무작위로 실시예 1 내지 5에 상응하는 (각 그룹 당 30명의 실험자가 있는) 5개의 그룹으로 나누었다. 본 발명에 의해 제공되는 상기 류머티즘 치료용 약제 플라스터가 상기 5개의 그룹에 의하여 각각 적용되었다. 1주 후, 효과를 관찰하였다. 적용 전의 상태와 비교했을 때, 통증 증상이 완전히 사라진 실험자는 ○로 표시하였으며, 통증 증상이 현저히 완화된 실험자는 △로 표시하였고, 통증 증상에 현저한 완화가 없었던 실험자는 Х로 표시하였다. 그 효과를 표 2에 나타내었다.150 male or female subjects (25 to 40 years of age) suffering from different rheumatic rheumatoid pain symptoms were selected and randomly corresponded to Examples 1 to 5 (with 30 experimenters in each group) Divided into groups of dogs. The pharmaceutical plaster for rheumatism provided by the present invention was applied to each of the five groups. After 1 week, the effect was observed. When compared with the state before application, the experimenter in which the pain symptoms completely disappeared was denoted by ○, the experimenter in which the pain symptom was significantly relieved was indicated by △, and the experimenter who had no significant relief in the pain symptom was denoted by Х. Table 2 shows the effect.
상기 실험 결과로부터, 본 발명에 의해 제공되는 류머티즘 치료용 약제 플라스터는 인체에서 류머티즘을 효과적으로 제거할 수 있으며, 류머티즘에 의해 발생하는 허리 통증을 완화시키는 좋은 기술적 효과를 달성할 수 있음을 알 수 있다. 본 발명에 의해 제공되는 류머티즘 치료용 약제 플라스터의 1주 적용 후, 허리의 류머티즘 통증 증상이 효과적으로 완화되거나 제거될 수 있음이 입증되었다.From the above experimental results, it can be seen that the pharmaceutical plaster for rheumatism treatment provided by the present invention can effectively remove rheumatism from the human body and achieve a good technical effect of alleviating back pain caused by rheumatism. After one week of application of the pharmaceutical plaster for rheumatism treatment provided by the present invention, it has been demonstrated that the symptoms of rheumatic pain in the lower back can be effectively relieved or eliminated.
(2) 어깨 및 목의 류머티즘 통증의 완화(2) Rheumatism pain relief of shoulder and neck
어깨 및 목 부위는 에어컨에 의해 발생하는 풍습(wind dampness)으로 인한 류머티즘이 발생하기 쉽다. 어깨 및 목의 류머티즘 통증을 겪고 있는 환자들 중에, 서로 다른 강도의 어깨 및 목 통증 증상이 있는 (20 내지 35세의) 150명의 남성 또는 여성 환자들을 선택하여, 무작위로 실시예 1 내지 5에 대응되는 (각 그룹 당 30명의 환자들이 있는) 5개의 그룹으로 나누었다. 본 발명에 의해 제공되는 상기 류머티즘 치료용 약제 플라스터가 상기 5개의 그룹에 의하여 각각 적용되었다. 1주 후, 효과를 관찰하였다. 적용 전의 상태와 비교했을 때, 통증 증상이 완전히 사라진 환자는 ○로 표시하였으며, 통증 증상이 현저히 완화된 환자는 △로 표시하였고, 통증 증상에 현저한 완화가 없었던 환자는 Х로 표시하였다. 그 효과를 표 3에 나타내었다.Rheumatism due to wind dampness caused by air conditioning is likely to occur in the shoulder and neck areas. Among patients suffering from rheumatism pain in the shoulder and neck, 150 male or female patients (ages 20 to 35) with different intensity of shoulder and neck pain symptoms were selected and randomly corresponded to Examples 1 to 5 Divided into 5 groups (with 30 patients in each group). The rheumatoid therapeutic plaster provided by the present invention was applied by each of the five groups. After 1 week, the effect was observed. When compared to the condition before application, patients with complete pain symptoms were denoted by ○, patients with significantly relieved pain symptoms were denoted by △, patients with no significant relief from pain symptoms were denoted by Х. Table 3 shows the effect.
상기 실험 결과로부터, 본 발명에 의해 제공되는 류머티즘 치료용 약제 플라스터는 모든 한방 약제 원료의 시너지 효과를 충분히 발휘할 수 있으며, 어깨 및 목 류머티즘 부위에 직접적으로 작용할 수 있어, 환자들의 통증 증상을 효과적으로 완화시킬 수 있음을 알 수 있다.From the above experimental results, the pharmaceutical plaster for rheumatism treatment provided by the present invention can sufficiently exert the synergistic effect of all herbal medicine raw materials, and can directly act on the rheumatism area of the shoulder and neck, effectively alleviating the pain symptoms of patients You can see that you can.
(3) 관절 류머티즘 통증의 완화(3) Relief of joint rheumatism pain
류머티즘에 의해 발생된 관절 통증 증상을 겪고 있는 (20 내지 50세의) 150명의 남성 또는 여성 시험자를 선택하고, 무작위로 실시예 1 내지 5에 상응하는 (각 그룹 당 30명의 테스터가 있는) 5개의 그룹으로 나누었다. 본 발명에 의해 제공되는 상기 류머티즘 치료용 약제 플라스터가 상기 5개의 그룹에 의하여 각각 적용되었다. 1주 후, 효과를 관찰하였다. 적용 전의 상태와 비교했을 때, 통증 증상이 완전히 사라진 시험자를 ○로 표시하였으며, 통증 증상이 현저히 완화된 시험자를 △로 표시하였고, 통증 증상에 현저한 완화가 없었던 시험자를 Х로 표시하였다. 그 효과를 표 4에 나타내었다.150 male or female subjects (from 20 to 50 years of age) suffering from joint pain symptoms caused by rheumatism were selected and 5 randomly (with 30 testers in each group) corresponding to Examples 1 to 5 Divided into groups. The rheumatoid therapeutic plaster provided by the present invention was applied by each of the five groups. After 1 week, the effect was observed. When compared with the state before application, the tester who completely disappeared from the pain symptoms was marked with ○, and the tester with significantly relieved pain symptoms was marked with △, and the tester who had no significant relief from the pain symptoms was marked with Х. Table 4 shows the effect.
상기 실험 결과로부터, 본 발명에 의해 제공되는 류머티즘 치료용 약제 플라스터가 관절 류머티즘 통증의 치료에 좋은 효과를 가지며, 각각의 한방 약제 원료의 약제 특성 및 그의 시너지 효과를 효과적으로 발휘할 수 있고, 외용만으로도 시험자의 통증을 현저히 완화시킬 수 있으며; 본 발명에 의해 제공되는 류머티즘 치료용 약제 플라스터가 독성 및 부작용이 없음을 알 수 있다.From the above experimental results, the pharmaceutical plaster for rheumatism treatment provided by the present invention has a good effect on the treatment of rheumatoid pain in the joint, and can effectively exert the pharmaceutical properties and synergistic effect of each herbal medicine raw material, and the external use of the tester Can significantly relieve pain; It can be seen that the pharmaceutical plaster for rheumatism provided by the present invention has no toxicity and side effects.
결론적으로, 상기 류머티즘 치료용 약제 플라스터는 필요한 부위에 적용하기만 하여도, 다양한 류머티즘에 의해 발생하는 각 부위의 통증을 효과적으로 완화시킬 수 있다.In conclusion, the pharmaceutical plaster for the treatment of rheumatism can effectively relieve pain in each region caused by various rheumatism by simply applying it to the necessary region.
Claims (4)
상기 류머티즘 치료용 약제 플라스터는
상기 원료들 모두를 혼합하여 혼합물을 얻고, 물을 첨가하여 상기 혼합물을 갈아 페이스트를 얻는 단계;
상기 페이스트를 약불에서 50 내지 70분 동안 물로 달이는 단계로서, 상기 물은 페이스트의 상태를 유지하기에 적절한 양으로 존재하는 단계; 및
상기 가열된 페이스트를 냉각하여 냉각된 페이스트 약제를 얻고, 상기 냉각된 페이스트 약제를 류머티즘 치료용 약제 플라스터 직물 상에 도포하는 단계에 의해 제조되는, 류머티즘 치료용 약제 플라스터.30 to 40 parts by weight of soft magnetic core; Wild chrysanthemum 20 to 30 parts by weight; 15 to 20 parts by weight of CheonShimRyun; A pharmaceutical plaster for rheumatism treatment comprising 10 to 15 parts by weight of honeyweed and 3 to 7 parts by weight of mint oil,
The rheumatism treatment plaster is
Mixing all the raw materials to obtain a mixture, and adding water to grind the mixture to obtain a paste;
Defrosting the paste with water for about 50 to 70 minutes on low heat, wherein the water is present in an amount suitable to maintain the state of the paste; And
Cooling the heated paste to obtain a cooled paste medicament, and is prepared by the step of applying the cooled paste medicament on a pharmaceutical plaster fabric for rheumatism treatment, pharmaceutical plaster for rheumatism treatment.
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CN115737256A (en) * | 2021-09-03 | 2023-03-07 | 李泓胜 | Therapeutic device based on rheumatism Miao medicine and formula thereof |
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