CN1883576A - Externally applied medicine for treating hyperosteogeny and intervertebral disc protrusion - Google Patents
Externally applied medicine for treating hyperosteogeny and intervertebral disc protrusion Download PDFInfo
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- CN1883576A CN1883576A CN 200610083253 CN200610083253A CN1883576A CN 1883576 A CN1883576 A CN 1883576A CN 200610083253 CN200610083253 CN 200610083253 CN 200610083253 A CN200610083253 A CN 200610083253A CN 1883576 A CN1883576 A CN 1883576A
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Abstract
Disclosed is a medicament for treating osteoproliferation and disc herniation, which comprises the following characterized in that it is prepared from the following Chinese medicinal materials (by weight proportion): honeysuckle flower 10-30, Chinese angelica root 5-15, eucommia bark 5-15, buck grass 10-30, sappan wood 5-15, dandehon herb 10-30, spatholobus stem 10-30, and cinnamon twig 10-30.
Description
Technical field
The invention belongs to external Chinese medicine technical field of pharmaceuticals, relate in particular to a kind of external used medicine that is used for the treatment of hyperosteogeny, intervertebral disc prolapse.
Background technology
Bone matrix hyperplasia belongs to the traditional Chinese medical science " arthromyodynia " category, also claims " rheumatism involving the bone ".The traditional Chinese medical science thinks that primary disease is relevant with wound, strain, obstruction of collaterals by blood stasis, the damp that is affected by the cold, phlegm resistance, caused by liver and kidney deficiency etc.Doctor trained in Western medicine claims the disease of hyperosteogeny and initiation thereof to be called osteoarthritis change, hypertrophic arthropathy change, osteoarthritis, degenerative bone change or the like.Lumbar vertebra hyperosteogeny can be oppressed contiguous neural blood vessel, causes sciatic nerve paralysis pain, and severe patient can cause lower extremity paralysis or muscle atrophia; Hyperosteogeny of cervical vertebra can be oppressed cervical plexus, shoulder plexus and vertebral artery, causes two handss, omoplate, giddy, headache, severe patient to make the not enough anoxia of blood supply in brain, causes a series of clinical symptoms.
The traditional Chinese medical science is thought intervertebral disk hernia and deficiency in origin and is marked reality. the wet exopathogen person that is affected by the cold, and how real its card is, and how anxious morbidity is; Because person due to the deficiency of the kidney, how empty its card is, and how slow morbidity is.Intervertebral disk hernia is divided into: bulging, give prominence to, deviate from, symptom is varied.Intervertebral disc is between adjacent two vertebral bodys, and by inside and outside bipartition, the outside is a fibrous ring, is made up of the fibrocartilaginous ring that multilamellar is arranged in the form of a ring, be centered around vertebral pulp around, can prevent that vertebral pulp is outwards outstanding, tenacity fiber and flexible; Inside is vertebral pulp, is a kind of whippy colloid substance, and the ballistic effect of mitigation is arranged.Adult intervertebral disc generation degenerative change, glass degeneration so that eventual failure take place in the fibre thickening in the fibrous ring, make intervertebral disc lose original elasticity, can not undertake the pressure that bore originally.In excessive strain, the position cataclysm, action or violence are clashed into sudden force, and vertebral pulp is outwards outstanding through the crack of disruptive fibrous ring, forms intervertebral disk hernia.
The therapeutic modality of bone matrix hyperplasia and intervertebral disc prolapse has multiple, generally adopts unidirectional current ion medicine introductory technique, massage and pull needle moxibustion therapy, surgical therapy and Chinese medicine method to treat both at home and abroad.
Summary of the invention
The purpose of this invention is to provide a kind of treatment hyperosteogeny and intervertebral disc prolapse Chinese medicine externally used compound, it can effectively cure various hyperosteogenys and neck, prolapse of lumbar intervertebral disc from the morbidity source.
The technical solution used in the present invention is as follows;
A kind of external used medicine for the treatment of hyperosteogeny, intervertebral disc prolapse is characterized in that this medicine is made up of following Chinese medicine raw materials by weight proportion:
Flos Lonicerae 10～30 Radix Angelicae Sinensis 5～15 Cortexs Eucommiae 5～15
Radix Clematidis 2～8 Flos Carthamis 10～30 Herba speranskiae tuberculataes 5～15
Herba Lycopodii 10～30 Lignum Sappans 5～15 Herba Taraxacis 10～30
Caulis Spatholobi 10～30 Ramulus Cinnamomi 10～30
The external used medicine of this treatment hyperosteogeny, intervertebral disc prolapse is made up of Chinese medicine raw materials by weight proportion specific as follows:
Flos Lonicerae 20 Radix Angelicae Sinensis 10 Cortexs Eucommiae 10
Radix Clematidis 5 Flos Carthamis 20 Herba speranskiae tuberculataes 10
Herba Lycopodii 20 Lignum Sappans 10 Herba Taraxacis 20
Caulis Spatholobi 20 Ramulus Cinnamomi 20
This medicine is that raw material of Chinese medicine adds the externally used paste that vegetable oil and Plumbum preparatium or Hydrocerussitum (Ceruse) etc. are refined through high temperature.
In the employed raw material of Chinese medicine of external used medicine of the present invention, Flos Lonicerae is the dry flower of caprifoliaceae plant Radix Ophiopogonis, Flos Lonicerae, Flos Lonicerae or hair style Radix Ophiopogonis or the flower that band is just opened.Sweet in the mouth, cold in nature, return lung, the heart, stomach warp.Heat-clearing and toxic substances removing is arranged, the function of wind-heat dissipating.When the dry root that is classified as umbelliferae angelica, sweet in the mouth, suffering, warm in nature, return liver, the heart, spleen channel.Can enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.The Cortex Eucommiae is the dry bark of the Eucommiaceae plant Cortex Eucommiae.Sweet in the mouth, warm in nature, return liver, kidney channel.The energy invigorating the liver and kidney, bone and muscle strengthening, antiabortive.Radix Clematidis is the dry root and rhizome of ranunculaceae plant Radix Clematidis, cotton-wool iron wire or northeast clematis.Acrid in the mouth, salty, warm in nature, return urinary bladder channel.Has expelling wind and removing dampness, the effect of removing obstruction in the collateral to relieve pain.Flos Carthami is the dried floral of feverfew Flos Carthami.Acrid in the mouth, warm in nature, GUIXIN, Liver Channel.But promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Herba speranskiae tuberculatae claims MANSHANXIANG again, is the stem and leaf of ericad Yunnan Gaultheria.Acrid in the mouth, warm in nature, cure mainly expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral.Herba Lycopodii is the dry herb of lycopsid Lycopodium clavatum.Mildly bitter flavor, suffering, warm in nature, return the liver,spleen,kidney warp.The energy expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.Lignum Sappan is the dry duramen of leguminous plant Lignum Sappan.Sweet in the mouth, salty, property is flat, GUIXIN, liver, spleen channel.Energy promoting the circulation of blood blood stasis dispelling, reducing swelling and alleviating pain.Herba Taraxaci is feverfew Herba Taraxaci, alkali ground Herba Taraxaci or the dry herb that belongs to several plants together.Bitter in the mouth, sweet, cold in nature.Return liver, stomach warp.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.Caulis Spatholobi is the dry rattan of leguminous plant spatholobus suberectus.Bitter in the mouth, sweet, warm in nature, return liver, kidney channel.Have and enrich blood, invigorate blood circulation, the effect of collateral dredging.Ramulus Cinnamomi is the cinnamomic dry twig of canella.Acrid in the mouth, sweet, warm in nature.GUIXIN, lung, urinary bladder channel.But the diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.
This external used medicine is from eliminating the paathogenic factor of hyperosteogeny, intervertebral disk hernia, caused by liver and kidney deficiency, wound and strain just, affection of exogenous wind-cold damp, phlegm resistance and acute and chronic wound are started with, directly be affixed on the part, functions of detumescence, relieving inflammation be can reach, compressing, replenishing essence bone strengthening, benefiting vital QI and blood, expel wind to dredge collateral, damp eliminating cold expelling, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving removed the adjacent nerve blood vessel, thereby blood circulation promoting effectively, repair the tissue of local damage, thoroughly eliminate its intrinsic factor, reach the effect for the treatment of both the principal and the secondary aspects of a disease at the same time.
The dosage form of this external used medicine can be general unguentum, is about to effective Chinese medicinal components and refines the black plaster that obtains with Plumbum preparatium or Hydrocerussitum (Ceruse) high temperature in vegetable oil; Also can be to be the Colophonium plaster of substrate with Colophonium.The glossy exquisiteness of its outward appearance is to the skin nonirritant.
It is effective ingredient that the external used medicine of this treatment hyperosteogeny, intervertebral disc prolapse adopts Chinese herbal medicine, can fundamentally eliminate the paathogenic factor and the clinical symptoms of hyperosteogeny, intervertebral disk hernia, reaches the purpose of thorough healing.Its medication is simple, the cure rate height, and have the advantage that has no side effect.This external used medicine can be used for treating hyperosteogeny, neck prolapse of lumbar intervertebral disc and spinal canal stenosis disease.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment and application experiment.
Embodiment 1 gets each component of this external used medicine by following weight:
The Flos Lonicerae 200 gram Radix Angelicae Sinensis 100 gram Cortexs Eucommiae 100 grams
Radix Clematidis 50 gram Flos Carthamis 200 gram Herba speranskiae tuberculataes 100 grams
Herba Lycopodii 200 gram Lignum Sappans 100 gram Herba Taraxacis 200 grams
Caulis Spatholobi 200 gram Ramulus Cinnamomi 200 gram Oleum sesami 2000 grams
Plumbum preparatium 400 grams
Above-mentioned raw materials is refined into the black unguentum of external by traditional handicraft, make externally applied ointment with kraft paper or cloth, the weight of whenever forcing on is 50 grams, and its active drug content is 43%.
The inventor carries out the multiple dosing skin irritation test to this external medicine preparation, repeatedly contacts the local excitation reaction that produces behind this medicine unguentum to observe intact skin.
10 of adult healthy white mouse are selected in experiment for use, with white mouse spinal column both sides unhairing, check after the unhairing whether skin of unhairing damages before the administration.Undamaged skin is made the administration irritant experiment.It is softening earlier this plaster to be added the excipient Oleum sesami before the experiment, sticks this plaster 6 grams then, and area is about 30m
2Every animal sub-cage rearing, after the administration 5 days, remove residual ointment with the warm water washing, removing medicine detects by an unaided eye after 1 hour and writes down medicine and smear the position and have or not erythema and water kind situation, observe subsides medicine position simultaneously whether situations such as pigmentation, petechia, pachylosis and epidermatic atrophy are arranged, successive administration 6 times each 5 days, was observed after the drug withdrawal 5 again.Experimental result shows, sticks this medicine unguentum continuously after 6 days, has 2 inadequate visible erythema and visible edema to occur in 10 white mouse, is removing this medicine unguentum after 1 day, erythema and edematous condition complete obiteration.The external used medicine unguentum that this shows this treatment hyperosteogeny and intervertebral disk hernia repeatedly belongs to " nonirritant " to the local excitation reaction that intact skin produced after the medication.
The external medicine preparation that inventor's Application Example 1 provides carries out the clinical treatment experiment to hyperosteogeny and intervertebral disk hernia patient.Patient's 349 examples of seeing and treating patients altogether, the age between 35～75 years old, lumbar vertebra hyperosteogeny patient 86 examples wherein, hyperosteogeny of cervical vertebra patient 134 examples, prolapse of lumbar intervertebral disc patient's 129 examples.Therapeutic Method is for to stick this external used medicine unguentum at lesions position, and every dose is about 50 grams, every dose 7 days, 5 to paste be a course of treatment, treatment time needs 35 altogether.
Diagnosis, healing, produce effects and the invalid standard of treatment are as follows:
1. the diagnostic criteria of hyperosteogeny of cervical vertebra disease (cervical spondylosis): with the shoulder back pain, the feeling of numbness of acupuncture sample or electric shock sample is arranged behind patient's the neck; Restriction of neck motion, numbness of the fingers or pain, grasp weakness, the finger activity is ineffective, fine movement difficulty etc.Headache, dizzy, cerebral ischemia appear sometimes; When head turns to a certain orientation, promptly feel dizzy, nauseating, vomiting, tinnitus, deafness, blurring of vision etc.; Suddenly numb limbs and tense tendons, paraesthesia, it is unable or symptom such as fall down suddenly to hold thing.The X line is taken the photograph the sheet inspection: the physiology curvature of cervical vertebra changes.
2. the diagnostic criteria of prolapse of lumbar intervertebral disc: the X line is taken the photograph the sheet inspection: scoliosis, and waist physiology lordosis disappears, and neighboring edge has osteophytosis.Scoliosis, the lumbar vertebra physiologic radian disappears, and the diseased region vertebra is other tenderness, and to lower limb radiation, waist limitation of activity.Have half patient to show as skelalgia after the first lumbago approximately, have 1/3 patient painful and have a pain in the leg and take place simultaneously for the back approximately, it is painful to occur the back after having a pain in the leg then appears earlier in other small part patients.
Criterion of cure: various symptom complete obiterations, functional rehabilitation is normal, takes the photograph the sheet inspection through the X line, and the hypertrophy hyperosteogeny disappears or dwindles.
The produce effects standard: various symptoms partly disappear or are eased, but complete obiteration not yet.
Invalid standard: symptom does not have any improvement.
Observe through clinical diagnosis, treatment, use this external Chinese medicine above-mentioned disease be the results are shown in Table 1.
This external used medicine of table 1 is to the therapeutic outcome of hyperosteogeny and intervertebral disc prolapse
| Cure example | Cure rate | The produce effects example | Obvious effective rate | Invalid example | Inefficiency | Total effective rate | |
| Hyperosteogeny of cervical vertebra | 75 | 87.2％ | 11 | 12.8％ | 0 | 0％ | 100％ |
| Lumbar vertebra hyperosteogeny | 116 | 86.6％ | 12 | 9.0％ | 6 | 4.4％ | 95.6％ |
| Prolapse of lumbar intervertebral disc | 112 | 86.8％ | 15 | 11.6％ | 2 | 1.6％ | 98.4％ |
As can be seen from the above table, all more than 85%, total effective rate is all more than 95% to the cure rate of hyperosteogeny and intervertebral disc prolapse for this external used medicine.The inventor finds that invalid example is older, and the patient that the course of disease is long analyzes its reason, may be that the adhesion and the fibrosis of pathological changes local organization is heavier, or prolapse of lumbar intervertebral disc is bigger, and simultaneously with due to the bone matrix hyperplasia.
Embodiment 2 gets each component of this external used medicine by following weight:
The Flos Lonicerae 100 gram Radix Angelicae Sinensis 150 gram Cortexs Eucommiae 50 grams
Radix Clematidis 80 gram Flos Carthamis 300 gram Herba speranskiae tuberculataes 150 grams
Herba Lycopodii 100 gram Lignum Sappans 50 gram Herba Taraxacis 100 grams
Caulis Spatholobi 300 gram Ramulus Cinnamomi 100 gram Colophonium 1000 grams
Above-mentioned raw materials is refined into external Colophonium cream by traditional handicraft, make externally applied ointment with cloth, the weight of whenever forcing on is 50 grams, and its active drug content is about 65%.
Embodiment 3 gets each component of this external used medicine by following weight:
The Flos Lonicerae 300 gram Radix Angelicae Sinensis 50 gram Cortexs Eucommiae 150 grams
Radix Clematidis 20 gram Flos Carthamis 100 gram Herba speranskiae tuberculataes 50 grams
Herba Lycopodii 300 gram Lignum Sappans 150 gram Herba Taraxacis 300 grams
Caulis Spatholobi 100 gram Ramulus Cinnamomi 300 gram Oleum sesami 1500 grams
Hydrocerussitum (Ceruse) 50 grams
Above-mentioned raw materials is refined into the white cream of external by traditional handicraft, make externally applied ointment with cloth, the weight of whenever forcing on is 50 grams, and its active drug content is about 45%.
Claims (3)
1. external used medicine for the treatment of hyperosteogeny, intervertebral disc prolapse is characterized in that this medicine is made up of following Chinese medicine raw materials by weight proportion:
Flos Lonicerae 10～30 Radix Angelicae Sinensis 5～15 Cortexs Eucommiae 5～15
Radix Clematidis 2～8 Flos Carthamis 10～30 Herba speranskiae tuberculataes 5～15
Herba Lycopodii 10～30 Lignum Sappans 5～15 Herba Taraxacis 10～30
Caulis Spatholobi 10～30 Ramulus Cinnamomi 10～30
2. the external used medicine of treatment hyperosteogeny according to claim 1, intervertebral disc prolapse is characterized in that this medicine is made up of Chinese medicine raw materials by weight proportion specific as follows:
Flos Lonicerae 20 Radix Angelicae Sinensis 10 Cortexs Eucommiae 10
Radix Clematidis 5 Flos Carthamis 20 Herba speranskiae tuberculataes 10
Herba Lycopodii 20 Lignum Sappans 10 Herba Taraxacis 20
Caulis Spatholobi 20 Ramulus Cinnamomi 20
3. the external used medicine of treatment hyperosteogeny according to claim 1, intervertebral disc prolapse is characterized in that this medicine is that raw material of Chinese medicine adds the externally used paste that vegetable oil and Plumbum preparatium or Hydrocerussitum (Ceruse) etc. are refined through high temperature.
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| CN 200610083253 CN1883576A (en) | 2006-06-01 | 2006-06-01 | Externally applied medicine for treating hyperosteogeny and intervertebral disc protrusion |
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| CN 200610083253 CN1883576A (en) | 2006-06-01 | 2006-06-01 | Externally applied medicine for treating hyperosteogeny and intervertebral disc protrusion |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101422531B (en) * | 2007-10-29 | 2011-04-06 | 严现坤 | Wind-expelling pain-assuaging paste capable of treating lumbar intervertebral disc protrusion |
| CN103301216A (en) * | 2013-06-26 | 2013-09-18 | 陈黎光 | Ant cervical spondylosis recovering oil liniment and preparation method thereof |
| CN104127633A (en) * | 2014-07-24 | 2014-11-05 | 黄武 | Traditional Chinese medicine composition extract for treating hyperosteogeny and preparation method thereof |
| CN104208317A (en) * | 2014-09-03 | 2014-12-17 | 杨国军 | External-use linimentum for treating hyperostosis and rheumatism cold-and-heat diseases and preparation method of external-use linimentum |
| CN104383139A (en) * | 2014-10-23 | 2015-03-04 | 蒋法林 | Traditional Chinese medicine for treating lumbar disc protrusion |
| CN109674863A (en) * | 2019-03-06 | 2019-04-26 | 黄玉清 | A kind of composition for treating waist cervical vertebra |
-
2006
- 2006-06-01 CN CN 200610083253 patent/CN1883576A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101422531B (en) * | 2007-10-29 | 2011-04-06 | 严现坤 | Wind-expelling pain-assuaging paste capable of treating lumbar intervertebral disc protrusion |
| CN103301216A (en) * | 2013-06-26 | 2013-09-18 | 陈黎光 | Ant cervical spondylosis recovering oil liniment and preparation method thereof |
| CN103301216B (en) * | 2013-06-26 | 2014-07-16 | 陈黎光 | Ant cervical spondylosis recovering oil liniment and preparation method thereof |
| CN104127633A (en) * | 2014-07-24 | 2014-11-05 | 黄武 | Traditional Chinese medicine composition extract for treating hyperosteogeny and preparation method thereof |
| CN104208317A (en) * | 2014-09-03 | 2014-12-17 | 杨国军 | External-use linimentum for treating hyperostosis and rheumatism cold-and-heat diseases and preparation method of external-use linimentum |
| CN104208317B (en) * | 2014-09-03 | 2017-10-24 | 杨国军 | Treat externally-applied liniment of osteoproliferation and the cold febrile illness of rheumatism and preparation method thereof |
| CN104383139A (en) * | 2014-10-23 | 2015-03-04 | 蒋法林 | Traditional Chinese medicine for treating lumbar disc protrusion |
| CN109674863A (en) * | 2019-03-06 | 2019-04-26 | 黄玉清 | A kind of composition for treating waist cervical vertebra |
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