KR20200073389A - A medicated plaster for treating rheumatism - Google Patents
A medicated plaster for treating rheumatism Download PDFInfo
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- 239000011505 plaster Substances 0.000 title claims abstract description 40
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000000203 mixture Substances 0.000 claims abstract description 6
- 238000000034 method Methods 0.000 claims abstract description 5
- 238000001816 cooling Methods 0.000 claims abstract description 4
- 239000004744 fabric Substances 0.000 claims abstract description 4
- 244000286838 Eclipta prostrata Species 0.000 claims abstract description 3
- 235000006679 Mentha X verticillata Nutrition 0.000 claims abstract description 3
- 235000002899 Mentha suaveolens Nutrition 0.000 claims abstract description 3
- 235000001636 Mentha x rotundifolia Nutrition 0.000 claims abstract description 3
- 241000219977 Vigna Species 0.000 claims abstract description 3
- 239000003814 drug Substances 0.000 claims description 55
- 229940079593 drug Drugs 0.000 claims description 48
- 238000011282 treatment Methods 0.000 claims description 41
- 239000002994 raw material Substances 0.000 claims description 6
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims description 5
- 235000019477 peppermint oil Nutrition 0.000 claims description 5
- 240000001417 Vigna umbellata Species 0.000 claims description 4
- 235000011453 Vigna umbellata Nutrition 0.000 claims description 4
- 238000010257 thawing Methods 0.000 claims description 3
- 239000003921 oil Substances 0.000 claims description 2
- 235000019198 oils Nutrition 0.000 claims description 2
- 235000011171 Thladiantha grosvenorii Nutrition 0.000 abstract description 2
- 239000004615 ingredient Substances 0.000 abstract description 2
- 241001409321 Siraitia grosvenorii Species 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 238000010298 pulverizing process Methods 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 description 28
- 230000000694 effects Effects 0.000 description 19
- 208000024891 symptom Diseases 0.000 description 11
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- 210000003739 neck Anatomy 0.000 description 5
- 206010030113 Oedema Diseases 0.000 description 3
- 230000002195 synergetic effect Effects 0.000 description 3
- 229940126585 therapeutic drug Drugs 0.000 description 3
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- 230000007812 deficiency Effects 0.000 description 2
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
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- 230000007721 medicinal effect Effects 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
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- 208000006820 Arthralgia Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000016285 Movement disease Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 244000185386 Thladiantha grosvenorii Species 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000003028 elevating effect Effects 0.000 description 1
- 210000003195 fascia Anatomy 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
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- 230000004054 inflammatory process Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 210000003041 ligament Anatomy 0.000 description 1
- 230000008338 local blood flow Effects 0.000 description 1
- 210000001365 lymphatic vessel Anatomy 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000001640 nerve ending Anatomy 0.000 description 1
- 231100000956 nontoxicity Toxicity 0.000 description 1
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- 230000000144 pharmacologic effect Effects 0.000 description 1
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- 230000011514 reflex Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 230000001839 systemic circulation Effects 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 230000010415 tropism Effects 0.000 description 1
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/483—Gleditsia (locust)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Abstract
Description
본 발명은 한약 분야에 관한 것으로, 특히 류마티즘 치료용 약물처리된 플라스터(Plaster)에 관한 것이다.The present invention relates to the field of Chinese medicine, and more particularly, to a drug-treated plaster for the treatment of rheumatism.
류마티스 통증은 주로 관절, 근육 및 뼈 주위의 연조직(근육의 힘줄, 인대, 점액낭, 근막 등)을 공격하는 질환에 의해 야기된 국소 또는 전신의 통증을 말한다. 류마티스 통증 질병은 마비의 일종으로, 풍(Windness) 질병 인자와 습(Wetness) 질병 인자의 조합에 의해 야기되는 전통 중국 의학 분야로 간주된다. 통증 이외에도, 관절 병변은 부종과 운동 장애가 동반되고, 악화(attack)와 차도(remission)가 번갈아 일어나는 만성적인 경과를 보여준다. 환자의 혈액순환이 원활하지 않기 때문에, 근육이나 조직에서 요구되는 영양분들이 혈액순환을 통해 운반될 수 없어, 환자의 근육의 영양분 부족을 야기하고, 근육의 노화를 가속시키며 및 근육을 뻣뻣하게 만든다. Rheumatoid pain refers to local or systemic pain caused mainly by diseases that attack soft tissues (muscle tendons, ligaments, mucous sacs, fascia, etc.) around joints, muscles, and bones. Rheumatoid pain disease is a type of paralysis and is considered to be a traditional field of Chinese medicine caused by a combination of wind and wet disease factors. In addition to pain, joint lesions show a chronic course with alternating edema and movement disorders, alternating attacks and remissions. Because the patient's blood circulation is not smooth, the nutrients required by the muscles or tissues cannot be transported through the blood circulation, causing deficiencies in the patient's muscles, accelerating aging of the muscles and making the muscles stiff.
류마티즘-치료용 약물처리된 플라스터를 도포하는 치료법은 전통 중국 의학 임상 적용에서 일반적으로 사용되는 외부 치료법 중 하나로, 류마티즘 치료용 약물처리된 플라스터는 피부를 통해 작용한다; 류마티즘-치료용 약물처리된 플라스터를 도포하는 치료법은 약효, 지시사항 및 중국 의학의 귀경이론(the channel tropism)은 물론, 중국 의학의 증후군 차별화 및 치료의 원칙을 따른다; 따라서, 류마티즘-치료용 약물처리된 플라스터를 도포하는 치료법은 한약 원재료의 시너지 효과를 충분히 발휘해 다의약품 화합물 처방을 제공할 수 있어, 좋은 의학적 효과를 얻을 수 있다. 류마티즘 치료용 약물처리된 플라스터는 체표면에서 체표면 상에 직접 도포되기 때문에, 류마티즘 치료용 약물처리된 플라스터를 만드는데 사용되는 대부분의 의약 원료는 향이 짙고, 향기로운 향을 가진 방향성 약제(channel-ushering medicine)이고, 이동성이 높은 약을 사용하고, 피부에 침투하여 경락(meridians)과 내장에 들어갈 수 있어, 기(Qi)와 혈(blodd)의 조절하고, 메리디안(meridians)을 끌어올리고, 냉-습(cold-dampness)을 없애고, 부종과 통증을 완화시키는 등의 효과를 달성할 수 있다.The treatment of applying rheumatism-therapeutic drug-treated plaster is one of the external treatments commonly used in traditional Chinese medical clinical applications, and the drug-treated plaster for rheumatism treatment acts through the skin; Treatment with rheumatism-therapeutic drug-treated plasters follows the principles of drug differentiation and treatment in Chinese medicine, as well as medicinal efficacy, instructions and the channel tropism of Chinese medicine; Therefore, the treatment method of applying rheumatism-therapeutic drug-treated plaster can sufficiently exert the synergistic effect of the Chinese medicine raw material and provide a prescription for a multi-drug compound, thereby obtaining a good medical effect. Since the drug-treated plaster for rheumatism treatment is applied directly from the body surface to the body surface, most of the pharmaceutical raw materials used to make the drug-treated plaster for rheumatism treatment are channel-ushering medicine with a strong aroma and a fragrant aroma. ), using highly mobile drugs, penetrating the skin and entering the meridians and intestines, regulating Qi and blood, elevating meridians, and cold-humidity (cold-dampness) can be eliminated, and edema and pain relief can be achieved.
체표면에 도포되는 류마티즘 치료용 약물처리된 플라스터는 신경 말단을 자극하여 신경 반사를 일으키고, 차례로 혈관을 확장시키고, 국소 혈액순환을 촉진하며, 주변 조직의 영양을 개선하여 부종과 염증을 감소시키고, 고통을 경감시키는 목적을 달성한다. 동시에, 상기 약제는 피부를 통해 감염된 부위의 피하 조직에 침투하고, 국소 약물 농도의 상대적인 이점을 낳음으로써 강한 약리적 효과를 발휘한다. 또한, 류마티즘 치료용 약물처리된 플라스터는 강렬한 자극을 일으킬 수 있는 자극적인 의약을 몇몇 포함하고 있고, 그러한 강한 자극은 신경 반사를 일으켜 신체 기능을 조절하고, 항체 형성을 촉진하며, 인간 면역기능을 향상시킨다. 약물처리된 플라스터의 약제는 피부와 점막을 침투한 후, 혈관과 림프관을 통해 전신 순환계로 들어와서, 전신적인 약효를 발휘한다.Drug-treated plaster for rheumatism treatment applied to the body surface stimulates nerve endings, causing nerve reflex, in turn, expanding blood vessels, promoting local blood circulation, improving nutrition of surrounding tissues, reducing edema and inflammation, Achieve the purpose of alleviating pain. At the same time, the medicament exerts a strong pharmacological effect by penetrating the subcutaneous tissue of the affected area through the skin and producing a relative advantage of local drug concentration. In addition, drug-treated plasters for the treatment of rheumatism contain some stimulating medications that can cause intense stimulation, and such strong stimuli cause neuroreflex to regulate body function, promote antibody formation, and enhance human immune function Order. After the drug-treated plaster has penetrated the skin and mucous membranes, it enters the systemic circulation through blood vessels and lymphatic vessels, exerting systemic effects.
선행기술에는 신속하고 안정적인 효과와 적은 부작용을 갖는 류마티즘 치료용 약물처리된 플라스터가 없다.In the prior art, there is no drug-treated plaster for the treatment of rheumatism with rapid and stable effects and few side effects.
발명의 요약Summary of the invention
본 발명의 목적은 상기 선행기술의 부족함을 극복하고, 신속하고 안정적인 효과 및 적은 부작용을 가지며, 류마티즘 통증을 완화시킬 수 있는 류마티즘 치료용 약물처리된 플라스터를 제공하는 것이다.An object of the present invention is to provide a drug-treated plaster for the treatment of rheumatism, which overcomes the deficiencies of the prior art, has a rapid and stable effect and has little side effects, and can relieve rheumatic pain.
상기 목적을 위해, 본 발명은 나한과(Momordica grosvenori) 30 내지 40 중량부; 한련초(Eclipta alba) 20 내지 30 중량부; 덩굴팥(Vigna umbellate) 15 내지 20 중량부; 조각자(Spina gleditsiae) 10 내지 15 중량부 및 박하유(Mint oil) 3 내지 7 중량부를 포함하는 류마티즘 치료용 약물처리된 플라스터를 제공하고;For the above purpose, the present invention is 30 to 40 parts by weight of Nahan (Momordica grosvenori); 20 to 30 parts by weight of Hannyeoncho (Eclipta alba); Vigna umbellate 15 to 20 parts by weight; Providing a drug-treated plaster for the treatment of rheumatism comprising 10 to 15 parts by weight of Spina gleditsiae and 3 to 7 parts by weight of Mint oil;
상기 류마티즘 치료용 약물처리된 플라스터는 상기 원료들을 모두 혼합하여 얻은 혼합물을 갈아 물과 혼합하여 페이스트를 얻는 단계; The drug-treated plaster for rheumatism treatment comprises grinding the mixture obtained by mixing all the raw materials and mixing with water to obtain a paste;
온화한 불에 페이스트 상태를 유지하기 위한 적절한 양의 물을 사용하여 상기 페이스트를 50 내지 70분 동안 달이는 단계; 및 Defrosting the paste for 50 to 70 minutes using an appropriate amount of water to maintain the paste on a mild fire; And
상기 가열된 페이스트를 냉각시켜 냉각된 약물처리된 페이스트를 얻고, 상기 냉각된 약물처리된 페이스트를 류마티즘 치료용 약물처리된 플라스터 천에 바르는 단계에 의해 제조된다.It is prepared by cooling the heated paste to obtain a cooled drug-treated paste, and applying the cooled drug-treated paste to a drug-treated plaster cloth for rheumatism treatment.
사용을 위하여, 상기 류마티즘 치료용 약물처리된 플라스터는 다양한 류마티즘으로 인한 각 부위의 통증을 효과적으로 완화시키기 위해 필요한 위치에 도포하기만 하면 된다.For use, the drug-treated plaster for the treatment of rheumatism needs only to be applied at a position necessary to effectively relieve pain in each area due to various rheumatism.
본 발명에 의해 제공되는 류마티즘 치료용 약물처리된 플라스터는 신속하고 안정적인 효과와 적은 부작용 등의 장점을 갖는다.The drug-treated plaster for rheumatism provided by the present invention has advantages such as rapid and stable effect and less side effects.
본 발명의 다른 특징 또는 장점은 후술할 특정 실시예에서 상세히 설명될 것이다.Other features or advantages of the present invention will be described in detail in specific embodiments described below.
본 발명은 나한과 30 내지 40 중량부; 한련초 20 내지 30 중량부; 덩굴팥 15 내지 20 중량부; 조각자 10 내지 15 중량부 및 박하유 3 내지 7 중량부를 포함하는 류마티즘 치료용 약물처리된 플라스터를 제공하고;The present invention is 30 to 40 parts by weight of Nahan; 20-30 parts by weight of Hannyeoncho; 15-20 parts by weight of red beans; Providing a drug-treated plaster for rheumatism treatment comprising 10 to 15 parts by weight of the engraver and 3 to 7 parts by weight of peppermint oil;
상기 류마티즘 치료용 약물처리된 플라스터는 상기 원료들을 모두 혼합하여 얻은 혼합물을 갈아 물과 혼합하여 페이스트를 얻는 단계; The drug-treated plaster for rheumatism treatment comprises grinding the mixture obtained by mixing all the raw materials and mixing with water to obtain a paste;
온화한 불에 페이스트 상태를 유지하기 위한 적절한 양의 물을 사용하여 상기 페이스트를 50 내지 70분 동안 달이는 단계; 및 Defrosting the paste for 50 to 70 minutes using an appropriate amount of water to maintain the paste on a mild fire; And
상기 가열된 페이스트를 냉각시켜 냉각된 약물처리된 페이스트를 얻고, 상기 냉각된 약물처리된 페이스트를 류마티즘 치료용 약물처리된 플라스터 천에 바르는 단계에 의해 제조된다.It is prepared by cooling the heated paste to obtain a cooled drug-treated paste, and applying the cooled drug-treated paste to a drug-treated plaster cloth for rheumatism treatment.
사용을 위하여, 상기 류마티즘 치료용 약물처리된 플라스터는 다양한 류마티즘으로 인한 각 부위의 통증을 효과적으로 완화시키기 위해 필요한 위치에 도포하기만 하면 된다.For use, the drug-treated plaster for the treatment of rheumatism needs only to be applied at a position necessary to effectively relieve pain in each area due to various rheumatism.
이하, 실시예를 들어 본 발명을 상세히 설명한다. Hereinafter, the present invention will be described in detail with reference to Examples.
실시예 1 내지 5Examples 1 to 5
실시예 1 내지 5는 본 발명에 의해 제공된 류마티즘 치료용 약물처리된 플라스터를 설명하기 위해 사용된다.Examples 1 to 5 are used to describe drug-treated plasters for rheumatism treatment provided by the present invention.
실시예 1 내지 5에서, 류마티즘 1 내지 5를 치료하기 위한 약물처리된 플라스터가 표 1의 원료 비율에 따라 제조된다.In Examples 1 to 5, drug-treated plasters for treating rheumatism 1 to 5 are prepared according to the raw material ratios in Table 1.
실험예 1 내지 3Experimental Examples 1-3
실험예 1 내지 3은 본 발명이 제공하는 류마티즘 치료용 약물처리된 플라스터의 통증 완화 효과를 설명하기 위해 사용된 것이다.Experimental Examples 1 to 3 are used to explain the pain relief effect of the drug-treated plaster for rheumatism treatment provided by the present invention.
(1) 류머티즘으로 인한 허리 통증 완화(1) Relieving back pain due to rheumatism
다른 정도의 허리 류머티즘 통증을 겪는 남성 또는 여성 실험자 150명(25세 내지 40세)을 선택하였고, 실시예 1 내지 5에 해당하는 5개 그룹(각 그룹당 30명의 실험자)으로 무작위로 나누었다. 본 발명이 제공하는 류마티즘 치료용 약물처리된 플라스터를 5개 그룹에 각각 도포하였다. 1주 후, 효과가 관찰되었다. 도포 전의 상태와 비교하여, 통증 증상이 완전히 사라진 실험자는 ○으로 표시하였고, 통증 증상이 현저하게 완화된 실험자는 △로 표시하였으며, 통증 증상이 현저하게 완화되지 않은 실험자는 Х로 표시하였다. 그 효과를 표 2에 나타내었다.150 male or female experimenters (25 to 40 years old) suffering from different degrees of back rheumatism pain were selected and randomly divided into 5 groups corresponding to Examples 1 to 5 (30 experimenters in each group). The drug-treated plaster for rheumatism treatment provided by the present invention was applied to 5 groups, respectively. After 1 week, the effect was observed. Compared to the condition before application, the experimenter in which the pain symptom disappeared completely was denoted by ○, the experimenter in which the pain symptom was significantly relieved was indicated by △, and the experimenter in which the pain symptom was not significantly relieved was indicated by Х. Table 2 shows the effect.
상기 실험 결과로부터, 본 발명이 제공하는 류마티즘 치료용 약물처리된 플라스터는 인체의 류마티즘을 효과적으로 제거할 수 있고, 류마티즘에 의한 허리 통증을 경감시키는 우수한 기술적 효과를 달성할 수 있음을 알 수 있다. 본 발명이 제공하는 류마티즘 치료용 약물처리된 플라스터의 1주간 적용 후, 허리 류마티즘 통증 증상이 효과적으로 완화되거나 제거될 수 있음이 증명되었다.From the results of the experiment, it can be seen that the drug-treated plaster for rheumatism treatment provided by the present invention can effectively remove rheumatism of the human body and achieve excellent technical effects of reducing back pain caused by rheumatism. After one week of application of the drug-treated plaster for rheumatism treatment provided by the present invention, it has been demonstrated that the symptoms of back rheumatism pain can be effectively alleviated or eliminated.
(2) 어깨와 목의 류마티즘 통증 완화(2) Rheumatism pain relief of shoulder and neck
어깨와 목의 위치는 에어 컨디셔너로 인한 바람의 습기로 인해 류머티즘에 약하다. 어깨와 목의 류마티즘 통증을 겪는 환자 중, 다른 정도의 어깨와 목의 류머티즘 통증을 겪는 남성 또는 여성 실험자 150명(25세 내지 35세)을 선택하고 무작위로 실시예 1 내지 5에 해당하는 5개 그룹(각 그룹당 30명의 환자)으로 나누었다. 본 발명이 제공하는 류마티즘 치료용 약물처리된 플라스터를 5개 그룹에 각각 도포하였다. 1주 후, 효과를 관찰하였다. 도포 전의 상태와 비교하여, 통증 증상이 완전히 사라진 환자는 ○으로 표시하였고, 통증 증상이 현저하게 완화된 환자는 △로 표시하였으며, 통증 증상이 현저하게 완화되지 않은 환자는 Х로 표시하였다. 그 효과를 표 3에 나타내었다.The position of the shoulders and neck is vulnerable to rheumatism due to wind moisture caused by the air conditioner. Among patients suffering from rheumatism pain in the shoulder and neck, 150 male or female experimenters (25 to 35 years old) with rheumatism pain in different shoulders and necks were selected and randomly selected from 5 corresponding to Examples 1 to 5 It was divided into groups (30 patients per group). The drug-treated plaster for rheumatism treatment provided by the present invention was applied to 5 groups, respectively. After 1 week, the effect was observed. Compared to the condition before application, patients with complete pain symptoms were denoted by ○, patients with severe pain symptoms were denoted by △, and patients with severe pain symptoms were denoted by Х. Table 3 shows the effect.
상기 실험 결과로부터, 본 발명이 제공하는 류마티즘 치료용 약물처리된 플라스터는 모든 한약 원료들과 시너지 효과를 충분히 발휘할 수 있고, 어깨와 목의 류마티즘 부위에 직접 작용할 수 있음을 알 수 있으며, 이로써 환자의 통증 증상을 효과적으로 완화시킨다.From the results of the experiment, it can be seen that the drug-treated plaster for rheumatism treatment provided by the present invention can fully exhibit synergistic effects with all herbal ingredients and can directly act on the rheumatism area of the shoulder and neck, whereby the patient Effectively relieve pain symptoms.
(3) 관절 류마티즘 통증 완화(3) Relieve joint rheumatism pain
류마티즘에 의한 관절통을 겪는 남성 또는 여성 테스터 150명(25세 내지 50세)을 선택하고, 실시예 1 내지 5에 해당하는 5개 그룹(각 그룹당 30명의 테스터)으로 무작위로 나누었다. 본 발명이 제공하는 류마티즘 치료용 약물처리된 플라스터를 5개 그룹에 각각 도포하였다. 1주 후, 효과를 관찰하였다. 도포 전의 상태와 비교하여, 통증 증상이 완전히 사라진 환자는 ○으로 표시하였고, 통증 증상이 현저하게 완화된 환자는 △로 표시하였으며, 통증 증상이 현저하게 완화되지 않은 환자는 Х로 표시하였다. 그 효과를 표 4에 나타내었다.150 male or female testers (25 to 50 years old) suffering from joint pain due to rheumatism were selected and randomly divided into 5 groups corresponding to Examples 1 to 5 (30 testers in each group). The drug-treated plaster for rheumatism treatment provided by the present invention was applied to 5 groups, respectively. After 1 week, the effect was observed. Compared to the condition before application, patients with complete pain symptoms were denoted by ○, patients with severe pain symptoms were denoted by △, and patients with severe pain symptoms were denoted by Х. Table 4 shows the effect.
상기 실험 결과로부터, 본 발명의 류마티즘 치료용 약물처리된 플라스터는 관절 류마티즘 통증의 치료 효과가 우수하고, 각 한약재의 약성 및 이들과의 시너지 효과가 충분히 발휘될 수 있으며, 외부 사용 만에 의해서 테스터의 통증을 현저히 경감시킬 수 있고, 본 발명이 제공하는 류마티즘 치료용 약물처리된 플라스터는 독성 및 부작용이 없음을 알 수 있다.결론적으로, 상기 류마티즘 치료용 약물처리된 플라스터는 다양한 류마티즘으로 인한 각 부위의 통증을 효과적으로 완화하기 위해 필요한 부위에 적용하는 것 만이 필요하다.From the above experimental results, the drug-treated plaster for rheumatism treatment of the present invention has excellent treatment effect of joint rheumatism pain, the medicinal properties of each herbal medicine and the synergistic effect with them can be sufficiently exhibited, and the tester can be used only by external use. It can be significantly relieved pain, it can be seen that the drug-treated plaster for rheumatism treatment provided by the present invention has no toxicity and side effects. In conclusion, the drug-treated plaster for rheumatism treatment can be used for the treatment of various areas due to various rheumatism. It is only necessary to apply it to the area needed to effectively relieve the pain.
Claims (4)
상기 류마티즘 치료용 약물처리된 플라스터는
상기 원료들을 모두 혼합하여 혼합물을 얻고, 물을 첨가하여 상기 혼합물을 분쇄하여 페이스트를 얻는 단계;
온화한 불에 물과 함께 상기 페이스트를 50 내지 70분 동안 달이는 단계로서, 상기 물은 페이스트 상태를 유지하기 위한 적절한 양인, 단계; 및
상기 가열된 페이스트를 냉각시켜 냉각된 약물처리된 페이스트를 얻고, 상기 냉각된 약물처리된 페이스트를 류마티즘 치료용 약물처리된 플라스터 천에 바르는 단계에 의해 제조되는, 류마티즘 치료용 약물처리된 플라스터.
30-40 parts by weight of Mohandica grosvenori; 20 to 30 parts by weight of Hannyeoncho (Eclipta alba); Vigna umbellate 15 to 20 parts by weight; A drug-treated plaster for the treatment of rheumatism comprising 10 to 15 parts by weight of Spina gleditsiae and 3 to 7 parts by weight of Mint oil;
The rheumatism treatment drug-treated plaster
Mixing all the raw materials to obtain a mixture, and adding water to pulverize the mixture to obtain a paste;
Defrosting the paste with mild fire water for 50 to 70 minutes, wherein the water is an appropriate amount to maintain the paste state; And
Cooling the heated paste to obtain a cooled drug-treated paste, and manufactured by the step of applying the cooled drug-treated paste to a drug-treated plaster fabric for rheumatism treatment, the drug-treated plaster for rheumatism treatment.
The method according to claim 1, Nahan and 30 parts by weight; 20 parts by weight of Hannyeoncho; 15 parts by weight of red beans; Drug-treated plaster for the treatment of rheumatism, including 10 parts by weight of engraver and 3 parts by weight of peppermint oil.
The method according to claim 1, Nahan and 35 parts by weight; 25 parts by weight of Hannyeoncho; 17 parts by weight of red beans; A drug-treated plaster for the treatment of rheumatism comprising 12 parts by weight of an engraver and 5 parts by weight of peppermint oil.
The method according to claim 1, Nahan and 40 parts by weight; 30 parts by weight of Hannyeoncho; 20 parts by weight of red beans; A drug-treated plaster for rheumatism treatment comprising 15 parts by weight of engraver and 7 parts by weight of peppermint oil.
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