KR20200043583A - A medicated plaster - Google Patents
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- KR20200043583A KR20200043583A KR1020180123918A KR20180123918A KR20200043583A KR 20200043583 A KR20200043583 A KR 20200043583A KR 1020180123918 A KR1020180123918 A KR 1020180123918A KR 20180123918 A KR20180123918 A KR 20180123918A KR 20200043583 A KR20200043583 A KR 20200043583A
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- 239000011505 plaster Substances 0.000 title claims abstract description 30
- 239000002994 raw material Substances 0.000 claims abstract description 15
- 239000003814 drug Substances 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 244000144725 Amygdalus communis Species 0.000 claims abstract description 8
- 235000020224 almond Nutrition 0.000 claims abstract description 8
- 239000000203 mixture Substances 0.000 claims abstract description 8
- 235000011437 Amygdalus communis Nutrition 0.000 claims abstract description 6
- 238000001816 cooling Methods 0.000 claims abstract description 5
- 238000010298 pulverizing process Methods 0.000 claims abstract description 4
- 241000007126 Codonopsis pilosula Species 0.000 claims abstract description 3
- 244000241838 Lycium barbarum Species 0.000 claims abstract description 3
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 3
- 235000006679 Mentha X verticillata Nutrition 0.000 claims abstract description 3
- 235000002899 Mentha suaveolens Nutrition 0.000 claims abstract description 3
- 235000001636 Mentha x rotundifolia Nutrition 0.000 claims abstract description 3
- 239000004744 fabric Substances 0.000 claims abstract description 3
- 241000208340 Araliaceae Species 0.000 claims description 7
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 7
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 7
- 235000008434 ginseng Nutrition 0.000 claims description 7
- 244000163122 Curcuma domestica Species 0.000 claims description 5
- 235000003392 Curcuma domestica Nutrition 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 235000003373 curcuma longa Nutrition 0.000 claims description 5
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims description 5
- 235000019477 peppermint oil Nutrition 0.000 claims description 5
- 235000013976 turmeric Nutrition 0.000 claims description 5
- 239000003921 oil Substances 0.000 claims description 2
- 235000019198 oils Nutrition 0.000 claims description 2
- 230000000694 effects Effects 0.000 description 19
- 208000024891 symptom Diseases 0.000 description 13
- 208000010040 Sprains and Strains Diseases 0.000 description 8
- 241000411851 herbal medicine Species 0.000 description 8
- 229940079593 drug Drugs 0.000 description 5
- 230000006378 damage Effects 0.000 description 4
- 230000002195 synergetic effect Effects 0.000 description 4
- 230000000472 traumatic effect Effects 0.000 description 4
- 241000402754 Erythranthe moschata Species 0.000 description 3
- 206010024453 Ligament sprain Diseases 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 230000008736 traumatic injury Effects 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 230000011514 reflex Effects 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000008338 local blood flow Effects 0.000 description 1
- 210000001365 lymphatic vessel Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000001640 nerve ending Anatomy 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 231100000956 nontoxicity Toxicity 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000037368 penetrate the skin Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 239000002602 strong irritant Substances 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000001839 systemic circulation Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000010415 tropism Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
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Abstract
Description
본 발명은 한방약 (Chinese medicine)의 분야에 관한 것이며, 특히 약용 고약 (medicated plaster)에 관한 것이다. The present invention relates to the field of Chinese medicine, and particularly to medicated plaster.
피부를 통해 작용하는 약용 고약의 적용 요법은, 전통 한방약 임상 적용에서 일반적으로 사용되는 외부 치료 방법 중 하나이며; 약용 고약-적용 요법은 한방약에서 징후 (syndrome)의 판별 (differentiation) 및 치료뿐만 아니라 효험의 원칙, 징후 및 채널 향성 (channel tropism)을 따르고; 약용 고약-적용 요법은, 우수한 효과를 달성하도록, 모든 한방약 원료의 상승적 효과를 충분히 발휘할 수 있고, 다수의-약제 화합물 처방 (multi-medicine compound prescription)을 제공할 수 있다. 약용 고약은 신체 표면 상에 직접 적용되기 때문에, 약용 고약의 제조에 사용되는 대부분의 약제 (medicine)는 냄새가 진하고 (thick), 향기로운 향 및 고도의 이동성 (high migration)을 갖는 채널-어셔링 (channel-ushering) 약제가 추가로 사용되며, 이들은 기 (Qi) 및 혈액 조절 효과, 경선 준설 (dredging meridians), 오한 (cold-dampness) 해소, 부기 및 통증 완화 등의 효과를 달성하도록 피부에 스며들어 경선 (meridian) 및 내장으로 진입한다. The application therapy of medicinal plasters acting through the skin is one of the external treatment methods commonly used in traditional herbal medicine clinical applications; Medicinal plaster-applied therapies follow the principles of efficacy, signs and channel tropism as well as differentiation and treatment of syndrome in herbal medicine; The medicinal plaster-applied therapy can sufficiently exert the synergistic effect of all herbal medicine raw materials to achieve an excellent effect, and can provide a multi-medicine compound prescription. Since medicinal plasters are applied directly on the body surface, most of the medicines used in the manufacture of medicinal plasters are channel-asserting with a thick, fragrant aroma and high migration. Channel-ushering agents are additionally used, and these are impregnated into the skin to achieve effects such as Qi and blood control, dredging meridians, relieving cold-dampness, and relief from swelling and pain. Enter the meridians and viscera.
한방약 외과용 (surgical) 약용 고약은, 우수한 효과를 달성하도록, 한방약 채널 향성 원리를 따르며, 한방약 원료의 상승적 효과를 활용하고, 다수의-약제 화합물 처방을 제공한다. 약용 고약은 피부 바깥쪽에 직접 적용되며, 약용 고약은 냄새가 진한 약제를 사용하고, 울체 (stagnation)를 제거하고 병소 (nidus)에 직접 작용하도록 약제를 유도할 수 있는 유도-약제 (guide-medicine)를 추가로 포함한다. 따라서, 약용 고약은 피부에 스며들어 염증 감소, 통증 완화, 혈액순환 활성화로 인한 울혈 제거, 경선 준설, 소생 (resuscitation) 유도 및 골 관통 (bone penetrating), 오한 해소 등의 효과를 달성할 수 있다. 신체 표면에 적용되는 약용 고약은, 부기 및 염증을 감소시키고 통증을 완화시키는 목적을 달성하기 위하여, 신경 말단 (nerve ending)을 자극하고 신경 반사 (nervous reflex)를 일으켜, 결국에는 혈관을 확장시키고, 국소 혈액 순환을 촉진시키며, 주변 조직의 영양 작용 (nutrition)을 개선시킨다. 동시에, 약제는 피부를 통하여 이환된 부위의 피하 조직으로 침투하고, 국소 약제 농도의 상대적인 이점을 창출하여, 강력한 약리학적 효과를 발휘한다. 또한, 약용 고약은 강력한 자극을 발생시킬 수 있는 강한 자극성 약제 (irritant medicine)를 일부 함유하며, 이러한 강력한 자극은 신경 반사를 일으켜, 결국에는 신체 기능을 조절하고, 항체 형성을 촉진시키고, 인간 면역을 강화시킨다. 약제가 피부 및 점막을 침투한 후, 이들은 혈관 또는 림프관을 통하여 체순환 (systemic circulation)으로 진입하고, 전신 약제 효과를 발휘한다. Herbal Medicine Surgical medicinal plasters follow the herbal medicine channel scent principle to achieve excellent effects, utilize the synergistic effects of herbal medicine raw materials, and provide multiple-pharmaceutical compound prescriptions. Medicinal plasters are applied directly to the outside of the skin, and medicinal plasters are guide-medicine that can be used to induce medicaments to remove stagnation and act directly on the nidus. It further includes. Therefore, the medicinal plaster can penetrate the skin to reduce inflammation, relieve pain, remove congestion due to blood circulation activation, dredge meridian, induce resuscitation, and achieve bone penetrating, cooling chills, and the like. Medicinal plasters applied to the body surface, to achieve the purpose of reducing swelling and inflammation and alleviating pain, stimulate nerve endings and cause nerve reflex, eventually expanding blood vessels, It promotes local blood circulation and improves nutrition of surrounding tissues. At the same time, the drug penetrates into the subcutaneous tissue of the affected area through the skin and creates a relative advantage of local drug concentration, exerting a strong pharmacological effect. In addition, medicinal plasters contain some strong irritant medicines that can generate strong stimuli, and these powerful stimuli cause neural reflexes, which eventually regulate body function, promote antibody formation, and promote human immunity. Strengthen. After the drug penetrates the skin and mucous membranes, they enter the systemic circulation through blood vessels or lymphatic vessels and exert a systemic drug effect.
종래 기술에서 대부분의 약용 고약은 사향 (musk)을 함유한다. 사향은 인체, 특히 임산부에게 특정한 부작용을 갖는다. Most medicinal plasters in the prior art contain musk. Musk has certain side effects for the human body, especially pregnant women.
본 발명에 의해 제공되는 약용 고약은 경구 투여를 필요로 하지 않으며, 단지 외용을 필요로 하고, 최소한의 부작용을 갖는다. The medicinal plaster provided by the present invention does not require oral administration, only external use and has minimal side effects.
본 발명의 목적은 종래 기술에서의 약용 고약의 건강-관리 효험 부족을 극복하고, 류마티스 (rheumatism) 및 외상성 손상 (traumatic injury)으로 유발된 통증을 효과적으로 경감시킬 수 있는, 사향을 함유하지 않는 약용 고약을 제공하는 것이다. The object of the present invention is to overcome the lack of health-care efficacy of medicinal plasters in the prior art, and to effectively relieve pain caused by rheumatism and traumatic injury, medicinal plasters containing no musk. Is to provide
이러한 목적으로, 본 발명은, 중량부 기준으로 (by weight parts), 하기 원료를 포함하는 약용 고약을 제공하며: 영하구기자 (Lycium barbarum L.) 20 내지 30 중량부; 만삼 (Codonopsis pilosula) 20 내지 30 중량부; 울금 (Radix curcumae) 15 내지 20 중량부; 아몬드 (Almond) 10 내지 15 중량부 및 박하유 (mint oil) 2 내지 4 중량부;For this purpose, the present invention, by weight parts (by weight parts), provides a medicinal plaster containing the following raw materials: 20 to 30 parts by weight (Lycium barbarum L.); 20 to 30 parts by weight of ginseng (Codonopsis pilosula); 15-20 parts by weight of Radix curcumae; Almond 10 to 15 parts by weight and mint oil 2 to 4 parts by weight;
상기 약용 고약은 하기의 단계로 제조된다:The medicinal plaster is prepared in the following steps:
상기의 모든 원료를 혼합하여 혼합물을 수득하고, 물을 첨가함으로써 상기 혼합물을 분쇄하여 반죽 (paste)을 수득하는 단계; Mixing all of the above ingredients to obtain a mixture, and pulverizing the mixture by adding water to obtain a paste;
상기 반죽을 약불 (gentle fire) 하에서 40 내지 60분 동안 물과 함께 달이는 (decocting) 단계로서, 여기서, 상기 물이 상기 반죽의 상태를 유지하기에 적절한 양인 것인, 단계;Decocting the dough with water for 40 to 60 minutes under gentle fire, wherein the water is in an amount suitable to maintain the state of the dough;
상기 가열된 반죽을 냉각시켜 냉각된 반죽 약제 (paste medicine)를 수득하는 단계; 및Cooling the heated dough to obtain cooled dough medicine; And
상기 냉각된 반죽 약제를 약용 고약 천 (medicated plaster cloth)에 적용하는 단계. Applying the cooled dough agent to a medicated plaster cloth.
사용을 위하여, 상기 약용 고약은 단지 필요한 위치에 적용되는 것을 필요로 하며, 류마티스, 염좌 (sprain), 외상성 손상에 의해 유발된 이러한 위치에서의 통증을 효과적으로 완화시킬 수 있다. For use, the medicinal plaster only needs to be applied at the required location and can effectively relieve pain at these locations caused by rheumatism, sprains, and traumatic damage.
본 발명에 의해 제공되는 약용 고약은 빠른 효과, 비 의존성 (no dependency)등의 이점을 갖는다. The medicinal plaster provided by the present invention has the advantages of quick effect, no dependency, and the like.
본 발명의 다른 특징 및 이점은 하기의 구체적인 실시형태에 상세히 예시될 것이다.Other features and advantages of the invention will be illustrated in detail in the following specific embodiments.
보편성을 잃지 않으면서, 본 발명은, 중량부 기준으로, 하기의 원료를 포함하는 약용 고약을 제공하며: 영하구기자 20 내지 30 중량부; 만삼 20 내지 30 중량부; 울금 15 내지 20 중량부; 아몬드 10 내지 15 중량부 및 박하유 2 내지 4 중량부;Without losing universality, the present invention provides, on a weight part basis, a medicinal plaster containing the following raw materials: 20 to 30 parts by weight of a reporter; 20 to 30 parts by weight of ginseng; Turmeric 15 to 20 parts by weight; 10 to 15 parts by weight of almonds and 2 to 4 parts by weight of peppermint oil;
상기 약용 고약은 하기의 단계로 제조된다:The medicinal plaster is prepared in the following steps:
상기의 모든 원료를 혼합하여 혼합물을 수득하고, 물을 첨가함으로써 상기 혼합물을 분쇄하여 반죽을 수득하는 단계; Mixing all of the above raw materials to obtain a mixture, and pulverizing the mixture by adding water to obtain a dough;
상기 반죽을 약불 하에서 40 내지 60분 동안 물과 함께 달이는 단계로서, 여기서, 상기 물이 상기 반죽의 상태를 유지하기에 적절한 양인 것인, 단계;Defrosting the dough with water for about 40 to 60 minutes under low heat, wherein the water is in an amount suitable to maintain the state of the dough;
상기 가열된 반죽을 냉각시켜 냉각된 반죽 약제를 수득하는 단계; 및Cooling the heated dough to obtain a cooled dough agent; And
상기 냉각된 반죽 약제를 약용 고약 천에 적용하는 단계. Applying the cooled dough agent to a medicinal plaster.
사용을 위하여, 상기 약용 고약은 단지 필요한 위치에 적용되는 것을 필요로 하며, 류마티스, 염좌, 외상성 손상 등에 의해 유발된 이러한 위치에서의 통증을 효과적으로 완화시킬 수 있다. For use, the medicinal plaster only needs to be applied at the required location and can effectively relieve pain at these locations caused by rheumatism, sprains, traumatic damage, and the like.
이후에, 본 발명은 실시예를 참조하여 상세히 설명될 것이다.Hereinafter, the present invention will be described in detail with reference to examples.
실시예 1 내지 5Examples 1 to 5
실시예 1 내지 5는 본 발명에 의해 제공되는 약용 고약을 예시하기 위하여 사용된다. Examples 1 to 5 are used to illustrate medicinal plasters provided by the present invention.
실시예 1 내지 5에서, 약용 고약 1 내지 5는 표 1의 원료 비율 (중량 기준)에 따라 제조된다.In Examples 1 to 5, medicinal plasters 1 to 5 are prepared according to the raw material ratio (by weight) in Table 1.
(g)Reporter
(g)
(g)Ginseng
(g)
(g)Turmeric
(g)
(g)almond
(g)
(g)peppermint oil
(g)
실험예 1 내지 5Experimental Examples 1 to 5
실험예 1 내지 5는 본 발명에 의해 제공되는 약용 고약의 통증 완화 효과를 예시하기 위하여 사용된다.Experimental Examples 1 to 5 are used to illustrate the pain relief effect of the medicinal plaster provided by the present invention.
(1) 류마티스에 의해 유발된 통증의 완화(1) Relief of pain caused by rheumatism
상이한 정도의 류마티스 통증 증상 (pain symptom)을 앓는 150명의 남성 또는 여성 실험자 (25 내지 40세)를 선택하고, 실시예 1 내지 5에 해당하는 5개 그룹 (각 그룹 당 30명의 실험자)으로 임의로 나눴다. 본 발명에 의해 제공되는 약용 고약을 5개 그룹에 각각 적용하였다. 1주 후, 효과를 관찰하였다. 적용 이전과 병증 (condition)을 비교하여, 통증 증상이 완전히 사라진 실험자를 ○로 표시하고, 통증 증상이 현저하게 완화된 실험자를 △로 표시하고, 통증 증상이 현저하게 완화되지 않은 실험자를 Х로 표시하였다. 효과를 표 2에 도시하였다. 150 male or female subjects (25-40 years old) with different degrees of rheumatic pain symptoms were selected and randomly divided into 5 groups corresponding to Examples 1-5 (30 subjects per group). . The medicinal plasters provided by the present invention were each applied to 5 groups. After 1 week, the effect was observed. By comparing the condition with the condition before application, the experimenter whose pain symptoms completely disappeared is indicated by ○, the experimenter with significantly relieved pain symptoms is indicated by △, and the experimenter with not significantly relieved pain symptoms is indicated by Х. Did. The effects are shown in Table 2.
상기의 실험 결과로부터, 본 발명에 의해 제공되는 약용 고약이 인체에서 류마티스를 효과적으로 경감시킬 수 있고, 류마티스에 의해 유발된 통증을 완화시키는 뛰어난 기술적 효과를 달성할 수 있다는 것을 알 수 있다. 이로써, 본 발명에 의해 제공되는 고약의 1주 적용 후, 류마티스 통증 증상이 효과적으로 완화되거나 또는 제거될 수 있다는 것이 증명되었다. From the above experimental results, it can be seen that the medicinal plaster provided by the present invention can effectively relieve rheumatism in the human body and achieve excellent technical effects for alleviating pain caused by rheumatism. Thus, it has been demonstrated that, after one week of application of the plaster provided by the present invention, rheumatoid pain symptoms can be effectively alleviated or eliminated.
(2) 염좌에 의해 유발된 통증의 완화(2) Relieve pain caused by sprains
다리, 발, 손, 허리 등의 위치에 염좌를 앓는 환자 중, 상이한 정도의 염좌 증상 (sprain symptom)을 갖는 150명의 남성 또는 여성 환자 (25 내지 35세)를 선택하고, 실시예 1 내지 5에 해당하는 5개 그룹 (각 그룹 당 30명의 환자)으로 임의로 나눴다. 본 발명에 의해 제공되는 약용 고약을 5개 그룹에 각각 적용하였다. 1주 후, 효과를 관찰하였다. 적용 이전과 병증을 비교하여, 통증 증상이 완전히 사라진 환자를 ○로 표시하고, 통증 증상이 현저하게 완화된 환자를 △로 표시하고, 통증 증상이 현저하게 완화되지 않은 환자를 Х로 표시하였다. 효과를 표 3에 도시하였다. Among patients suffering from sprains in the positions of legs, feet, hands, and back, 150 male or female patients (25 to 35 years old) with different degrees of sprain symptoms were selected, and in Examples 1 to 5 They were randomly divided into the corresponding 5 groups (30 patients per group). The medicinal plasters provided by the present invention were each applied to 5 groups. After 1 week, the effect was observed. Patients who had completely disappeared from the pain symptoms were marked with ○, and patients with significantly relieved pain symptoms were indicated by △, and patients with not significantly relieved pain symptoms were marked with Х. The effects are shown in Table 3.
상기의 실험 결과로부터, 다양한 염좌 증상이 효과적으로 완화될 수 있도록, 본 발명에 의해 제공되는 약용 고약이 모든 한방약 원료의 상승적 효과를 충분히 발휘할 수 있고, 염좌 위치에 직접 작용할 수 있다는 것을 알 수 있다. From the above experimental results, it can be seen that the medicinal plaster provided by the present invention can sufficiently exert a synergistic effect of all herbal medicine raw materials and directly act on the sprain position, so that various sprain symptoms can be effectively alleviated.
(3) 외상성 손상에 의해 유발된 통증의 완화(3) Pain relief caused by traumatic injury
(낙하 (falling down), 충돌 또는 외력으로 유발되는) 외상성 손상을 앓는 150명의 남성 또는 여성 시험자 (25 내지 40세)를 선택하고, 실시예 1 내지 5에 해당하는 5개 그룹 (각 그룹 당 30명의 시험자)으로 임의로 나눴다. 본 발명에 의해 제공되는 약용 고약을 5개 그룹에 각각 적용하였다. 1주 후, 효과를 관찰하였다. 적용 이전과 병증을 비교하여, 통증 증상이 완전히 사라진 환자를 ○로 표시하고, 통증 증상이 현저하게 완화된 환자를 △로 표시하고, 통증 증상이 현저하게 완화되지 않은 환자를 Х로 표시하였다. 효과를 표 4에 도시하였다. 150 male or female subjects (25-40 years old) suffering from traumatic injury (caused by falling down, collision or external forces) were selected and 5 groups corresponding to Examples 1-5 (30 per group) (Test subjects). The medicinal plasters provided by the present invention were each applied to 5 groups. After 1 week, the effect was observed. Patients who had completely disappeared from the pain symptoms were marked with ○, and patients with significantly relieved pain symptoms were indicated by △, and patients with not significantly relieved pain symptoms were marked with Х. The effects are shown in Table 4.
상기의 실험 결과로부터, 본 발명에 의해 제공되는 약용 고약이 외상성 손상에 의해 유발된 통증의 강력한 치료 및 완화 효과를 가지며, 각각의 한방약 원료의 의약적 특성 및 이의 상승적 효과를 충분히 발휘할 수 있고, 단지 외용으로써 시험자의 통증을 현저하게 완화시킬 수 있고; 본 발명에 의해 제공되는 약용 고약이 독성 및 부작용이 없다는 것을 알 수 있다. From the above experimental results, the medicinal plaster provided by the present invention has a powerful treatment and relieving effect of pain caused by traumatic damage, and can fully exhibit the medicinal properties and synergistic effects of each herbal medicine raw material, only External use can significantly relieve the pain of the investigator; It can be seen that the medicinal plaster provided by the present invention has no toxicity and side effects.
사용을 위하여, 상기 약용 고약은 단지 필요한 위치에 적용되는 것을 필요로 하며, 류마티스, 염좌, 외상성 손상 등에 의해 유발된 이러한 위치에서의 통증을 효과적으로 완화시킬 수 있다. For use, the medicinal plaster only needs to be applied at the required location and can effectively relieve pain at these locations caused by rheumatism, sprains, traumatic damage, and the like.
Claims (4)
영하구기자 (Lycium barbarum L.) 20 내지 30 중량부; 만삼 (Codonopsis pilosula) 20 내지 30 중량부; 울금 (Radix curcumae) 15 내지 20 중량부; 아몬드 (Almond) 10 내지 15 중량부 및 박하유 (mint oil) 2 내지 4 중량부;
상기 약용 고약은 다음의 단계로 제조되는, 약용 고약:
상기의 모든 원료를 혼합하여 혼합물을 수득하고, 물을 첨가함으로써 상기 혼합물을 분쇄하여 반죽 (paste)을 수득하는 단계;
약불 하에서 40 내지 60분 동안 상기 반죽을 물과 함께 달이는 (decocting) 단계로서, 여기서, 상기 물은 상기 반죽의 상태를 유지하기에 적절한 양인 것인, 단계;
상기 가열된 반죽을 냉각시켜 냉각된 반죽 약제 (paste medicine)를 수득하는 단계; 및
상기 냉각된 반죽 약제를 약용 고약 천 (medicated plaster cloth)에 적용하는 단계.By weight, as a medicated plaster comprising the following raw materials:
Journalist (Lycium barbarum L.) 20 to 30 parts by weight; 20 to 30 parts by weight of ginseng (Codonopsis pilosula); 15-20 parts by weight of Radix curcumae; Almond 10 to 15 parts by weight and mint oil 2 to 4 parts by weight;
The medicinal plaster is prepared by the following steps, medicinal plaster:
Mixing all the above raw materials to obtain a mixture, and pulverizing the mixture by adding water to obtain a paste;
Decocting the dough with water for 40 to 60 minutes under low heat, wherein the water is in an amount suitable to maintain the condition of the dough;
Cooling the heated dough to obtain cooled dough medicine; And
Applying the cooled dough agent to a medicated plaster cloth.
중량부 기준으로, 다음의 원료: 영하구기자 25 중량부; 만삼 25 중량부; 울금 16 중량부; 아몬드 12 중량부 및 박하유 2 중량부를 포함하는, 약용 고약. According to claim 1,
On the basis of parts by weight, the following raw materials: tertiary reporter 25 parts by weight; 25 parts by weight of ginseng; Turmeric 16 parts by weight; A medicinal plaster comprising 12 parts by weight of almond and 2 parts by weight of peppermint oil.
중량부 기준으로, 다음의 원료: 영하구기자 28 중량부; 만삼 25 중량부; 울금 17 중량부; 아몬드 12 중량부 및 박하유 3 중량부를 포함하는, 약용 고약. According to claim 1,
On the basis of parts by weight, the following raw materials: territorial reporter 28 parts by weight; 25 parts by weight of ginseng; Turmeric 17 parts by weight; A medicinal plaster, comprising 12 parts by weight of almond and 3 parts by weight of peppermint oil.
중량부 기준으로, 다음의 원료: 영하구기자 28 중량부; 만삼 26 중량부; 울금 17 중량부; 아몬드 13 중량부 및 박하유 4 중량부를 포함하는, 약용 고약.
According to claim 1,
On the basis of parts by weight, the following raw materials: territorial reporter 28 parts by weight; 26 parts by weight of ginseng; Turmeric 17 parts by weight; A medicinal plaster, comprising 13 parts by weight of almonds and 4 parts by weight of peppermint oil.
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