CN106266939A - A kind of Chinese medicine composition, the transdermal patch for neck waist rehabilitation comprising this Chinese medicine composition and preparation and application - Google Patents

A kind of Chinese medicine composition, the transdermal patch for neck waist rehabilitation comprising this Chinese medicine composition and preparation and application Download PDF

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Publication number
CN106266939A
CN106266939A CN201610703109.0A CN201610703109A CN106266939A CN 106266939 A CN106266939 A CN 106266939A CN 201610703109 A CN201610703109 A CN 201610703109A CN 106266939 A CN106266939 A CN 106266939A
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China
Prior art keywords
parts
radix
rhizoma
plaster
chinese medicine
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CN201610703109.0A
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Chinese (zh)
Inventor
王如昌
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Shandong Rendi Biological Engineering Co Ltd
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Shandong Rendi Biological Engineering Co Ltd
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Priority to CN201610703109.0A priority Critical patent/CN106266939A/en
Publication of CN106266939A publication Critical patent/CN106266939A/en
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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Abstract

The invention discloses a kind of Chinese medicine composition, the transdermal patch for neck waist rehabilitation comprising this Chinese medicine composition and preparation and application, described Chinese medicine composition includes the components such as the Radix Rehmanniae, Rhizoma Atractylodis, Radix Aconiti, Radix Aconiti Kusnezoffii, there is removing blood stasis stimulate the menstrual flow, the effect such as dispersing cold for relieving pain, dispeiling pathogenic wind and removing dampness, the rehabilitation of neck LBT can be effective to, the most also have quickly effectively, be difficult to recurrence, adapt to wide, bioavailability is high and to advantages such as human zero damages.Meanwhile, the transdermal patch for neck waist rehabilitation comprising this Chinese medicine composition of the present invention is a kind of to comprise female plaster and the externally applied transdermal patch of sub-plaster.Obtained transdermal patch acts on SHENYU acupoint and Weizhong point, it is possible to getting through governor vessel, relaxing muscles and tendons to promote blood circulation, activate neuron, activate two bladder warps, blood circulation promoting, the rehabilitation to neck waist relevant disease has good effect.The preparation method of the transdermal patch for neck waist rehabilitation disclosed by the invention, has the advantages such as preparation method simplicity, the good instant effect of drug absorption.

Description

A kind of Chinese medicine composition, comprise the transdermal for neck waist rehabilitation of this Chinese medicine composition Patch and preparation and application
Technical field
The present invention relates to Chinese medicine composition field, more particularly, to a kind of Chinese medicine composition, comprise this Chinese medicine composition The transdermal patch for neck waist rehabilitation and preparation method.
Background technology
Epidemiological study shows, neck lumbago is the disease that sickness rate is only second to flu, and almost all of people is in its all one's life In neck lumbago all can occur.Common neck lumbago is many because straining and caused by regression, belongs to flesh muscular rheumatism disease and osteoarthrosis arthromyodynia etc. The regression of spinal column be in human body in all histoorgans the earliest, the soonest, the most serious.Wherein neck lumbar vertebra is the upper and lower of physical activity Hinge, its regression is the fastest.
The common sympton of cervical pain discomfort includes the abnormal sensories such as head, neck, shoulder pain, and with corresponding pressure pain point. Feature is that Wry Neck, uncomfortable, pain and activity are dumb.The palm of serious patient or disease of hand, pain, grip Weakening, sometimes all think do not have power by cup, when being in a bad way, pain has difficulty in going to sleep whole night.The symptom also having patient is inclined head Bitterly, dizzy, dim eyesight, tinnitus, or uncomfortable in chest, chest pain, tachycardia, precordialgia etc..The common sympton that flank pain is uncomfortable Including chronic back pain, the course of disease is longer, touching difficulty more, the many dull pain of waist or ache.Often improper because of position, to overwork, weather becomes The factors such as change and increase the weight of.Meanwhile, lumbago can have lower waist to buttocks, thigh rear, little leg outer side until the radiating pain of foot, In the case of the abdominal pressure such as sneeze and cough increases, pain can be aggravated.Also show as stool, urine obstacle, perineum and crissum and feel different Often.Also there will be upper limb, lower limb pain, alter the nervous symptoms such as picotement.Serious neck pain in the lumbar region pain can give patient orthobiosis and Work causes serious impact, and physiology and psychology to patient cause dual torment, bring huge misery to patient.
Prior art mainly uses the sides such as expectant treatment, minimally-invasive treatment and operative treatment for the treatment of neck waist disease Formula.Physical therapy mode and the medicine Chinese medicine for oral administration external applications etc. such as expectant treatment includes massaging, draws, massages, acupuncture, the former is the most effective Slowly, the course for the treatment of is long, spends height, and final curative effect is not the most it is obvious that and substantially can not effect a radical cure, the long-term orthobiosis affecting patient. Medicine is for oral administration can not directly act on affected part, and curative effect is the most inconspicuous, and cure rate is the highest, and easily recurs, and first pass effect also can The dose making entrance body circulate reduces, drug effect reduces.External application of Chinese medicine great majority are the simple affected part that acts on, alleviating pain, Can not fundamentally treat and cure neck waist relevant disease, especially the most ill patient simply be cured the symptoms, not the disease.Wicresoft controls Treatment includes collagenase nucleolysis, Ozone ablation art, percutaneous rotary-cut art, PLDD etc..Although wound is little, but Have strict indication, to a lot of as strain, rheumatism because of etc. the waist neck pain that causes do not reach therapeutic effect, application surface mistake Narrow.Operative treatment is complicated, in irregular shape due to the anatomical structure of spinal column, has important spinal cord and nerve root in the canalis spinalis of spinal column Traveling, the strictest indication, there is great risk simultaneously, patients' neural may be caused to damage if there is unexpected or Directly result in paralysis and wait more serious consequence.
Therefore, exploitation can be used in neck waist rehabilitation the most effective, economical and practical, be difficult to recurrence, adapt to wide, targeting Good, bioavailability high and medicine to human zero damage, is also increasingly becoming the emphasis of research and development.
In view of this, the special proposition present invention.
Summary of the invention
It is an object of the present invention to provide a kind of Chinese medicine composition, described compositions has removing blood stasis by selection and leads to Warp, the pure Chinese drug-treated group distribution of the effects such as dispersing cold for relieving pain, dispeiling pathogenic wind and removing dampness, resolving depression of regulating the flow of vital energy, scattered blood and dissolving stasis, regulating qi and activating blood, easing joint movement 5 use, and the medical material used by each component and proportioning thereof are adjusted by the clinical trial repeatedly through decades, thus obtain Chinese medicine composition of the present invention.The present composition can be effective to the rehabilitation of neck LBT, the most also has quickly Effectively, economical and practical, be difficult to recurrence, adapt to wide, targeting good, bioavailability is high and to advantages such as human zero damages.
Second object of the present invention be to provide a kind of by described Chinese medicine composition be prepared from for neck waist rehabilitation Transdermal patch, in the present invention, described in the application of the invention, Chinese medicine composition is as raw material, can prepare a kind of for neck waist Rehabilitation comprise female plaster and the externally applied transdermal patch of sub-plaster.Obtained transdermal patch acts on SHENYU acupoint and Weizhong point, energy Enough play and get through governor vessel, relaxing muscles and tendons to promote blood circulation, activate neuron, activate the effect of two bladder warps, blood circulation promoting, to neck waist phase The rehabilitation of related disorders has good effect, and instant effect, is difficult to recurrence.
Third object of the present invention is to provide the preparation method of a kind of described transdermal patch for neck waist rehabilitation, should With Chinese medicine composition of the present invention as raw material in method, use the methods such as decoction, extraction that effective ingredient in compositions is carried out Extraction and application, allows medicament to preferably permeate from crust by mixing transdermal agent, enters body circulation, thus raw material is greatly improved The utilization rate of medicine, keeps the activity of crude drug effective ingredient.There is the advantages such as preparation method simplicity, the good instant effect of drug absorption.
For reaching above-mentioned purpose, the present invention uses following technical proposals:
A kind of Chinese medicine composition, is combined by two kinds of components being used in conjunction with each other of A and B;
Described component A is made up of the raw material of following weight portion: Radix Rehmanniae 4-14 part, Rhizoma Atractylodis 4-14 part, Fructus Aurantii 4-14 part, slender acanthopanax Skin 4-14 part, Rhizoma Curcumae 4-14 part, Semen Persicae 4-14 part, Rhizoma Kaempferiae 4-14 part, Radix Angelicae Sinensis 4-14 part, Pericarpium Citri Reticulatae 4-14 part, Radix Linderae 4-14 part, three Rib 4-14 part, Radix Et Rhizoma Rhei 4-14 part, Radix Polygoni Multiflori 4-14 part, Radix Bupleuri 4-14 part, Radix Saposhnikoviae 4-14 part, Herba Artemisiae Anomalae 4-14 part, Rhizoma Chuanxiong 4-14 part, Rhizoma Et Radix Notopterygii 4-14 part, Radix Clematidis 4-14 part, Radix Paeoniae Rubra 4-14 part, Rhizoma Cyperi 4-14 part, Herba Schizonepetae 4-14 part, white positive 4-14 part, Caulis Piperis Kadsurae 4- 14 parts, Rhizoma Ligustici 4-14 part, Radix Dipsaci 4-14 part, Rhizoma Alpiniae Officinarum 4-14 part, Radix Angelicae Pubescentis 4-14 part, Herba Ephedrae 4-14 part, dry and soft 4-14 part, Fructus Forsythiae 4- 14 parts, Radix Aucklandiae 2-10 part, Radix Aconiti Lateralis Preparata 2-10 part, Flos Carthami 5-15 part;
Described B component is made up of the raw material of following weight portion: Radix Aconiti 4-14 part, Radix Aconiti Kusnezoffii 4-14 part, Fructus Gleditsiae Abnormalis 4-14 part, Cortex Cinnamomi 4-14 part, Rhizoma Arisaematis 4-14 part, Fructus Foeniculi 4-14 part, Olibanum 4-14 part, Myrrha 4-14 part, Herba Asari 4-14 part, Crinis Carbonisatus 30-90 Part.
In the above-mentioned Chinese medicine composition of the present invention, selected raw material effect and effect are as follows:
Radix Aconiti: acrid in the mouth, warm in nature.Hands is returned to faint the moon, shaoyin channel.There is dispelling cold and dampness, dissipate ailment said due to cold or exposure, effect of antalgic.For Anemofrigid-damp arthralgia.Severe and migratory arthralgia pain, spasm of the limbs.
Radix Aconiti Kusnezoffii: bitter in the mouth is pungent, extremely hot in nature.Return liver, spleen, lung three warp.Have and search wind prevailing over dampness, effect of dispersing cold for relieving pain.For wind Cold-damp numbness, paralysis due to windstroke.
Fructus Gleditsiae Abnormalis: acrid in the mouth is bitter, property heat.Return liver, stomach two warp.Have sensible, search effect of wind.For apoplexy locked mouth, obstruction and rejection is not Logical.
Cortex Cinnamomi: bitter in the mouth is pungent, property heat.GUIXIN, spleen, lung, kidney four warp.There is complement positive, warming the spleen and stomach, removing accumulated cold, promoting blood circulation Effect.For decline of the fire from the gate of life, chills and pain of the waist and kness.
Rhizoma Arisaematis: sweet in the mouth, warm in nature.Return lung, liver, spleen three warp.There is drying dampness to eliminate phlegm, expelling wind for relieving convulsion, effect of dispersing swelling and dissipating binds. Mould for middle wind-phlegm, facial hemiparalysis, fall and flutter injured.
Fructus Foeniculi: acrid in the mouth, warm in nature.For dispersing cold for relieving pain, regulating qi-flowing for harmonizing stomach.
Olibanum: acrid in the mouth is bitter, warm in nature.GUIXIN, liver, spleen three warp.There is regulating qi and activating blood, analgesic therapy, chase after effect of poison.For trusted subordinate Cold type of pain, traumatic injury.
Myrrha: bitter in the mouth is pungent, warm in nature.Return spleen, kidney two warp.There is scattered blood and dissolving stasis, effect of subduing swelling and relieving pain.For falling damage, muscle Bone, all pains of trusted subordinate.
Herba Asari: acrid in the mouth, warm in nature.Return lung, kidney two warp.Have and dispel the wind, cold expelling, row water, the effect having one's ideas straightened out.For air-cooled head Bitterly, rheumatic arthralgia.
Crinis Carbonisatus: bitter in the mouth, warm in nature.GUIXIN, liver, kidney three warp.There is repercussive, effect of hemostasis.
The Radix Rehmanniae: sweet in the mouth, cold in nature.GUIXIN, liver, kidney channel.Curing mainly lumbar and pedal pain, seasonal epidemic pathogens pyretic toxicity, excessive thirst is had a headache, and break the muscle damages bone, logical Passages through which vital energy circulates, qi-restoratives is weak
Rhizoma Atractylodis: acrid in the mouth is bitter, warm in nature.Return spleen, stomach warp.There is stomach invigorating to pacify spleen, dampness diaphoresis, dissipate effect of wind QI invigorating.
Fructus Aurantii: bitter in the mouth, acid, cold nature.Return lung, spleen, stomach, large intestine four warp;There is dispelling the stagnated QI, row expectorant, removing food stagnancy, control wind, tonneau The effects such as joint.For distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, pruritus due to wind pathogen paralysis, tetraparesis.
Cortex Acanthopancis: acrid in the mouth, hardship, warm in nature.Return liver, kidney channel.There is the merits such as wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, blood circulation promoting and blood stasis dispelling Effect.For rheumatic arthralgia, muscles and bones flaccidity is soft, lumbago, flaccidity of the lower limbs, children's's walking retardation in children, and body void is weak, edema, tinea pedis.
Rhizoma Curcumae: bitter in the mouth is pungent, warm in nature.Return liver, spleen channel.There is removing blood stasis circulation of qi promoting, effect of removing food stagnancy pain relieving.For traumatic injury, Eating accumulation.
Semen Persicae: bitter in the mouth, property is put down.Return hands, meridian of Foot-JUE YIN.There is blood stasis removing and clots absorbing, moisturize effect of laxation.Store for calentura Blood, traumatic injury, congestion swells and ache.
Rhizoma Kaempferiae: acrid in the mouth, sweet, warm in nature.Return foot sun the moon bright, big, JUE YIN meridian.There is warming middle-JIAO, help digestion, effect of pain relieving.For Trusted subordinate's cold type of pain, stops dyspepsia, traumatic injury.
Radix Angelicae Sinensis: bitter in the mouth, warm in nature.GUIXIN, liver, lung three warp.There is effect of benefiting blood and regulating blood circulation.Cure mainly headache due to deficiency of blood, fall and flutter damage Wound.
Rhizoma Sparganii: bitter in the mouth, property is put down.Return lung, spleen two warp.There is removing blood stasis circulation of qi promoting, effect of removing food stagnancy pain relieving.For coagulation of QI-blood, Traumatic injury.
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature.Return stomach, large intestine, liver three warp, there is the poison that purges heat, removing mass stagnant, effect of blood stasis expelling blood.For reality Hot constipation, the stasis of blood close down through.
The Radix Polygoni Multiflori: sweet-bitter flavor, warm in nature.Return liver, kidney two warp.There is nourishing the blood and yin, loosening bowel to relieve constipation dispel the wind removing toxic substances effect.For Blood deficiency is dizzy, soreness of the waist and knees.
Radix Bupleuri: sweet in the mouth, cold in nature.GUIXIN, liver, spleen three warp.There is reconciling superficies and interior, effect of soothing the liver yang invigorating.Past for cold and heat Come, headache and dizziness.
Radix Saposhnikoviae: sweet in the mouth, warm in nature.Return bladder, lung, spleen three warp.Have and deliver, dispel the wind, win wet, effect of pain relieving.For outward Sense wind and cold, headache and dizziness, anemofrigid-damp arthralgia, joint is ached.
Herba Artemisiae Anomalae: bitter in the mouth, warm in nature.GUIXIN, spleen two warp.There is removing blood stasis stimulate the menstrual flow, effect of healing up sore and subduing swelling.Swollen for chest and abdomen Bitterly, traumatic injury, gold creates blood.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder two warp.There is activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, effect of promoting blood circulation and stopping pain.For Air-cooled headache, arthralgia due to cold clonic spasm of the muscle, tumbling and swelling.
Rhizoma Et Radix Notopterygii: bitter in the mouth is pungent, warm in nature.Return bladder, kidney two warp.There is scattered exterior cold, wind-damp dispelling, the effect in profit joint.For head The most lossless, anemofrigid-damp arthralgia, joint aches, edema due to wind pathogen edema.
Radix Angelicae Pubescentis: acrid in the mouth is bitter, warm in nature.Return kidney, bladder two warp.Have and dispel the wind, win wet, cold expelling, effect of pain relieving.For wind and cold Arthralgia chiefly caused by damp pathogen, soreness of waist and knee joint, the twin pain of trick.
Radix Clematidis: acrid in the mouth is salty, warm in nature.Return lung, kidney two warp.There is wind-damp dispelling, the meridian dredging, expectorant saliva, dissipate effect of the hypochondriac lump. For gout, insensitive impediment, chills and pain of the waist and kness.
Radix Paeoniae Rubra: sour in the mouth is bitter, cool in nature.Return liver, spleen two warp.There is clots absorbing pain relieving, effect of removing heat from blood detumescence.For stasis of blood stagnate-closed Warp, discharging fresh blood stool.
Rhizoma Cyperi: the micro-sweetness and bitterness of acrid in the mouth, property is put down.Return liver, three burnt two warps.There is the effect of resolving depression pain relieving regulating menstruation of regulating the flow of vital energy.For liver Discomfort in the stomach, depression of QI.
Herba Schizonepetae: acrid in the mouth, warm in nature.Return lung, liver two warp.Have and deliver, dispel the wind, effect for the treatment of blood disorders.For cold, fever, head Bitterly, apoplexy.
Bai Zheng: acrid in the mouth, warm in nature.Return lung, spleen, stomach three warp.There is wind-damp dispelling, evacuation of pus of invigorating blood circulation, effect of granulation promoting pain relieving.For Headache, toothache, hemorrhoidal hamorrhage anal fistula.
Caulis Piperis Kadsurae: acrid in the mouth is bitter, warm in nature.Return Liver Channel.There is wind-damp dispelling, the meridian dredging, the effect regulated the flow of vital energy.For anemofrigid-damp arthralgia, Arthralgia, muscle arteries and veins contracture, traumatic injury.
Rhizoma Ligustici: acrid in the mouth, warm in nature.Return bladder warp.There is effect of dispersing wind and cold damp.For headche due to wind-cold, cold-damp is suffered from abdominal pain.
Radix Dipsaci: bitter in the mouth is pungent, warm in nature.Return liver, kidney two warp.There is invigorating the liver and kidney, reuniting the fractured tendons and bones, effect of blood circulation regulating.For back Ache, the foot and knee being feeble, traumatic injury.
Rhizoma Alpiniae Officinarum: acrid in the mouth, warm in nature.Return spleen, stomach two warp.There is dispersing cold for relieving pain, effect of warming middle-JIAO to arrest vomiting.For cold syndrome of the stomach cold type of pain.
Herba Ephedrae: acrid in the mouth is bitter, warm in nature.Return lung, bladder two warp.There is diaphoresis, relieving asthma, effect of diuretic.It is real for typhoid fever table, Arthralgia, edema due to wind pathogen edema.
Dry and soft: sweet in the mouth, warm in nature.GUIXIN, spleen two warp.There is regulating QI to relieve pain, effect of activating spleen and strengthening stomach.For having a stomachache, chest and abdomen Distension, headache.
Fructus Forsythiae: bitter in the mouth, cold in nature.Return lung, the heart two warp.There is heat-clearing and toxic substances removing, effect of dispersing swelling and dissipating binds.For anemopyretic cold, Epidemic febrile disease.
The Radix Aucklandiae: there are promoting the circulation of QI to relieve pain, effect of strengthening the spleen to promote digestion.
Radix Aconiti Lateralis Preparata: sweet in the mouth, extremely hot in nature.GUIXIN, spleen, kidney three warp.There is recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, effect of dispelling cold and removing dampness. For preponderance of YIN refusing yang, trusted subordinate's cold type of pain, anemofrigid-damp arthralgia.
Flos Carthami: acrid in the mouth, warm in nature.GUIXIN, Liver Channel.There is promoting blood circulation to restore menstrual flow, effect of eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, dislike Revealing not all right, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, breast side of body twinge, injury from falling down, skin infection swells and ache.
Above material combination uses, and has removing blood stasis and stimulates the menstrual flow, dispersing cold for relieving pain, dispeiling pathogenic wind and removing dampness, resolving depression of regulating the flow of vital energy, scattered blood and dissolving stasis, tune Effects such as gas is invigorated blood circulation, easing joint movement, it is possible to be effective to the rehabilitation of neck LBT, the most also have the most effective, economical and practical, Be difficult to recurrence, adapt to wide, targeting good, bioavailability is high and to advantages such as human zero damages.
Preferably, component A of the present invention is made up of the raw material of following weight portion:: Radix Rehmanniae 7-11 part, Rhizoma Atractylodis 7-11 part, Fructus Aurantii 7-11 part, Cortex Acanthopancis 7-11 part, Rhizoma Curcumae 7-11 part, Semen Persicae 7-11 part, Rhizoma Kaempferiae 7-11 part, Radix Angelicae Sinensis 7-11 part, Pericarpium Citri Reticulatae 7-11 Part, Radix Linderae 7-11 part, Rhizoma Sparganii 7-11 part, Radix Et Rhizoma Rhei 7-11 part, Radix Polygoni Multiflori 7-11 part, Radix Bupleuri 7-11 part, Radix Saposhnikoviae 7-11 part, Herba Artemisiae Anomalae 7- 11 parts, Rhizoma Chuanxiong 7-11 part, Rhizoma Et Radix Notopterygii 7-11 part, Radix Clematidis 7-11 part, Radix Paeoniae Rubra 7-11 part, Rhizoma Cyperi 7-11 part, Herba Schizonepetae 7-11 part, Bai Zheng 7-11 part, Caulis Piperis Kadsurae 7-11 part, Rhizoma Ligustici 7-11 part, Radix Dipsaci 7-11 part, Rhizoma Alpiniae Officinarum 7-11 part, Radix Angelicae Pubescentis 7-11 part, Herba Ephedrae 7-11 part, dry Pine 7-11 part, Fructus Forsythiae 7-11 part, Radix Aucklandiae 5-7 part, Radix Aconiti Lateralis Preparata 5-7 part, Flos Carthami 8-12 part;
Described B component is made up of the raw material of following weight portion: Radix Aconiti 7-11 part, Radix Aconiti Kusnezoffii 7-11 part, Fructus Gleditsiae Abnormalis 7-11 part, Cortex Cinnamomi 7-11 part, Rhizoma Arisaematis 7-11 part, Fructus Foeniculi 7-11 part, Olibanum 7-11 part, Myrrha 7-11 part, Herba Asari 7-11 part, Crinis Carbonisatus 50-70 Part.
Preferably, component A of the present invention is made up of the raw material of following weight portion: 9 parts of the Radix Rehmanniae, Rhizoma Atractylodis 9 parts, Fructus Aurantii 9 parts, Cortex Acanthopancis 9 parts, Rhizoma Curcumae 9 parts, 9 parts of Semen Persicae, Rhizoma Kaempferiae 9 parts, Radix Angelicae Sinensis 9 parts, Pericarpium Citri Reticulatae 9 parts, Radix Linderae 9 parts, Rhizoma Sparganii 9 parts, Radix Et Rhizoma Rhei 9 parts, head Crow 9 parts, Radix Bupleuri 9 parts, Radix Saposhnikoviae 9 parts, Herba Artemisiae Anomalae 9 parts, Rhizoma Chuanxiong 9 parts, Rhizoma Et Radix Notopterygii 9 parts, Radix Clematidis 9 parts, Radix Paeoniae Rubra 9 parts, Rhizoma Cyperi 9 parts, chaste tree 9 parts of mustard, the most positive 9 parts, Caulis Piperis Kadsurae 9 parts, Rhizoma Ligustici 9 parts, Radix Dipsaci 9 parts, Rhizoma Alpiniae Officinarum 9 parts, Radix Angelicae Pubescentis 9 parts, 9 parts of Herba Ephedrae, dry and soft 9 parts, Fructus Forsythiae 9 Part, the Radix Aucklandiae 6 parts, Radix Aconiti Lateralis Preparata 6 parts, 10 parts of Flos Carthami;
Described B component is made up of the raw material of following weight portion: Radix Aconiti 9 parts, Radix Aconiti Kusnezoffii 9 parts, Fructus Gleditsiae Abnormalis 9 parts, Cortex Cinnamomi 9 part, day south 9 parts of star, Fructus Foeniculi 9 parts, Olibanum 9 parts, Myrrha 9 parts, Herba Asari 9 parts, Crinis Carbonisatus 60 parts.
In the present invention, by adjusting further and optimizing each Chinese medicinal components consumption, thus optimize this further Effect of bright compositions.
Further, described Chinese medicine composition is also prepared as the transdermal patch for neck waist rehabilitation by the present invention, described Transdermal patch by with the use of female plaster and sub-plaster form, described female plaster is by breathing freely patch and be attached to described Breathable paste Chinese medicine composition on cloth is constituted, and described sub-plaster is by patch and the Chinese medicine composition structure that is attached in described ventilative patch of breathing freely Become.
Preferably, described in described transdermal patch, on female plaster, the Chinese medicine composition of attachment is component A, described sub-plaster The Chinese medicine composition of upper attachment is B component.
Transdermal patch prepared by the Chinese medicine composition in the present invention is by treated in vitro, directly acts on affected part, is not subject to Gastric emptying rates etc. affect, it is to avoid in the metabolism that the organs such as the intestines and stomach, liver, kidney are unnecessary, improve drug utilization efficiency larger; Its effect is soft, significantly reduces the side effect of long-term prescription, without tackifiers such as Colophonium, little to skin irritation;User Just, without pain, dosage is accurate, and absorption area is fixed, and blood drug level is stable;Use the means of point application, it is possible to play Get through passages through which vital energy circulates, the effect of blood circulation promoting, improves the rehabilitation efficiency of neck LBT, reduces the misery of patient.
The present invention provide comprise with the use of female plaster and the transdermal patch of sub-plaster, in use, by mother's plaster Sticking in SHENYU acupoint, this acupuncture point is through belonging to bladder meridian.Shen shu, kidney, kidney is also;Yu, defeated also.Shen shu name means kidney Cold-damp aqueous vapor thus outer defeated bladder warp.Cold then first rush down the moxibustion mending afterwards or mend it, heat then rushes down it.Under the effect of the efficacy of a drug, by patient The cold-damp aqueous vapor passed over by kidney in internal SHENYU acupoint stops outer defeated bladder warp, and by discharging body after renal blood flow metabolism Outward.In addition massage SHENYU acupoint can be with waist pain-relieving., being pasted on Weizhong point by sub-plaster, Weizhong point is positioned at human body meanwhile Band midpoint, when the centre of biceps femoral muscle Yu semitendinosus m. tendon, this acupuncture point is through belonging to bladder meridian;In committee, committee, pile up Also.In, refer in cave QI and blood place be day middle part on three, people ground also.This cave name means that the damp and hot aqueous vapor of bladder warp is assembled at this. This cave material is bladder through the wet gas of water that each cave, portion at one's knees is up, for the up gas after heat absorption, at the shape that this cave is gathering, In therefore named committee.The disease that cures mainly in this cave is: sciatica, little leg fatigue, belly pain, neck pain, flank pain or tired Labor.
By the present invention provide a kind of for neck waist rehabilitation comprise with the use of female plaster and the transdermal of sub-plaster Patch, its female plaster sticks in stoping in SHENYU acupoint the cold-damp aqueous vapor passed over by kidney and stops outer defeated bladder warp, and by Excrete after renal blood flow metabolism.Meanwhile, sub-plaster is by gas damp eliminating cold expelling wet for the water coming into bladder warp, and promoting the circulation of blood Dredge the meridian passage.The two combines and SHENYU point can be made to form blood circulation stream with Weizhong point position, plays and gets through governor vessel, and relaxing muscles and tendons is lived Blood, activates neuron, activates effect of two bladder warps.So-called " getting through " is exactly to allow more QI and blood flow into.Governor vessel mainly follows Row is in human body posterior midline and head median line.The branch of governor vessel, goes together with bladder meridian, from inner canthus (inner eye corner) Go upward to volume, intersect at top, mountain peak, enter network in brain;Exiting again lower item, follow inside row omoplate, hold spinal column under the arm and arrive in waist, network is in kidney. The channels of governor vessel, from the beginning of the Changqiang acupoint of trunk foot, inside spinal column, spreads on head;The branch at back is from scapula Bladder meridian is moved towards in left and right.Therefore, governor vessel is the closest with bladder meridian relation, common connection kidney and brain.From following Seeing on walking along the street line, governor vessel, mainly at back, is carried on the back as sun, and therefore governor vessel has, to whole body yang channel arteries and veins gas, the effect commanded, supervise.Bladder Through being a toxin expelling passage maximum in health, it plays eliminating toxin, regulation internal organs, the effect of beauty and health care, is also health Resisting the important barrier of extraneous wind and cold, but bladder is through simply passage, unpowered operation itself, the support obtaining kidney qi can rise To resisting cold, effect of toxin expelling.The transdermal patch of the present invention can make SHENYU point form blood circulation stream with Weizhong point position, gets through and superintends and directs Arteries and veins, activates two bladder warps, plays exogenous cold and be difficult to invade, effect that endogenous toxin is discharged in time, thus reaches to make neck waist relevant disease The thoroughly purpose of rehabilitation.
Preferably, during described ventilative patch is elastical cloth, spun laced fabric, the waterproof patch of PU film or grey cotton fiber blend cloth Any one.
Further, present invention also offers the preparation method of a kind of described transdermal patch, specifically comprise the following steps that
(1) by 4-14 part Radix Rehmanniae, 4-14 part Rhizoma Atractylodis, 4-14 part Fructus Aurantii, 4-14 part Cortex Acanthopancis, 4-14 part Rhizoma Curcumae, 4-14 part Semen Persicae, 4-14 part Rhizoma Kaempferiae, 4-14 part Radix Angelicae Sinensis, 4-14 part Pericarpium Citri Reticulatae, 4-14 part Radix Linderae, 4-14 part Rhizoma Sparganii, 4-14 part Radix Et Rhizoma Rhei, 4-14 part The Radix Polygoni Multiflori, 4-14 part Radix Bupleuri, 4-14 part Radix Saposhnikoviae, 4-14 part Herba Artemisiae Anomalae, 4-14 part Rhizoma Chuanxiong, 4-14 part Rhizoma Et Radix Notopterygii, 4-14 part Radix Clematidis, 4- 14 parts of Radix Paeoniae Rubra, 4-14 part Rhizoma Cyperi, 4-14 part Herba Schizonepetae, 4-14 part are white the most just, 4-14 part Caulis Piperis Kadsurae, 4-14 part Rhizoma Ligustici, 4-14 part Radix Dipsaci, 4-14 part Rhizoma Alpiniae Officinarum, 4-14 part Radix Angelicae Pubescentis, 4-14 part Herba Ephedrae, 4-14 part are dry and soft, 4-14 part Fructus Forsythiae, 2-10 part Radix Aucklandiae, 2-10 part Radix Aconiti Lateralis Preparata, 5-15 part Flos Carthami mixes after pulverizing, and in mixture after boiling 70-100 minute, is cooled to 24-20 DEG C, filters First filtrate;
(2) described first filtrate extraction is obtained the first medicine extraction agent;
(3) in described first medicine extraction agent, add transdermal agent, be mixed to get the first ointment;
(4) described first ointment is coated in ventilative patch makes female plaster;
(5) by 4-14 part Radix Aconiti, 4-14 part Radix Aconiti Kusnezoffii, 4-14 part Fructus Gleditsiae Abnormalis, 4-14 part Cortex Cinnamomi, 4-14 part Rhizoma Arisaematis, 4-14 part Fructus Foeniculi, 4-14 part Olibanum, 4-14 part Myrrha, 4-14 part Herba Asari, 30-90 part Crinis Carbonisatus mix after pulverizing, and add water in mixture After decocting 40-55 minute, it is cooled to 24-20 DEG C, filters to obtain the second filtrate;
(6) described second filtrate extraction is obtained the second medicine extraction agent;
(7) in described second medicine extraction agent, add transdermal agent, be mixed to get the second ointment;
(8) described second ointment is coated in ventilative patch makes sub-plaster.
Preferably, described transdermal agent is laurocapram.
Preferably, the consumption of described laurocapram and the gross weight of each raw material are than being (0.1:10)-(1.5:10).
Preferably, the consumption of described laurocapram and the gross weight of each raw material are than being (0.6:10)-(1.0:10).
The present invention provide prepare a kind of for neck waist rehabilitation comprise with the use of female plaster and the transdermal of sub-plaster The method of patch, simple to operate, practical, economical and practical, environmental protection, the characteristic of the various ingredient of close fit, press Concoct according to suitable method, the utilization rate of crude drug can be greatly improved by the method, keep the work of crude drug effective ingredient Property, its crude drug effective rate of utilization reaches 90%.
Further, present invention also offers the using method of a kind of described transdermal patch, for waist relevant disease During rehabilitation, female plaster is applied to SHENYU acupoint, and sub-plaster is applied to Weizhong point;When the rehabilitation of cervical region relevant disease, female plaster Being applied to SHENYU acupoint, sub-plaster is applied to painful area.
Often patch can be applied ointment or plaster 4-7 days continuously.Use without taboo.
Beneficial effects of the present invention is as follows:
(1) Chinese medicine composition of the present invention can be effective to the rehabilitation of neck LBT, the most also have the most effectively, Economical and practical, be difficult to recurrence, adapt to wide, targeting good, bioavailability is high and to advantages such as human zero damages.
(2) Chinese medicine composition described in the application of the invention is as raw material, can prepare and comprise mother for neck waist rehabilitation The externally applied transdermal patch of plaster and sub-plaster.Obtained transdermal patch acts on SHENYU acupoint and Weizhong point, it is possible to plays to get through and superintends and directs Arteries and veins, relaxing muscles and tendons to promote blood circulation, activates neuron, activates the effect of two bladder warps, blood circulation promoting, collect two groups of drug influences and acupuncture point Effect is in one, and the rehabilitation to neck waist relevant disease has good effect, and instant effect, is difficult to recurrence.
(3) preparation method of the transdermal patch for neck waist rehabilitation of the present invention, with in of the present invention in the method Drug composition is raw material, uses the methods such as decoction, extraction to utilize extracts active ingredients in compositions, is made by mixing transdermal agent Medicine can preferably permeate from crust, enters body circulation, thus the utilization rate of crude drug is greatly improved, and keeps crude drug effective The activity of composition.There is the advantages such as preparation method simplicity, the good instant effect of drug absorption.
Detailed description of the invention
In order to be illustrated more clearly that the present invention, below in conjunction with preferred embodiment, the present invention is described further.Ability Field technique personnel should be appreciated that following specifically described content is illustrative and be not restrictive, and should not limit this with this The protection domain of invention.Unreceipted actual conditions person in embodiment, the condition advised according to normal condition or manufacturer is carried out.Institute With reagent or instrument unreceipted production firm person, being can be by the commercially available conventional products bought and obtain.
Embodiment 1
According to following prescription, weigh appropriate raw material, wherein, component A according to parts by weight respectively: 4 parts of the Radix Rehmanniae, Rhizoma Atractylodis 4 parts, Fructus Aurantii 4 parts, Cortex Acanthopancis 4 parts, Rhizoma Curcumae 4 parts, 4 parts of Semen Persicae, Rhizoma Kaempferiae 4 parts, Radix Angelicae Sinensis 4 parts, Pericarpium Citri Reticulatae 4 parts, Radix Linderae 4 parts, Rhizoma Sparganii 4 parts, big Huang 4 parts, the Radix Polygoni Multiflori 4 parts, Radix Bupleuri 4 parts, Radix Saposhnikoviae 4 parts, Herba Artemisiae Anomalae 4 parts, Rhizoma Chuanxiong 4 parts, Rhizoma Et Radix Notopterygii 4 parts, Radix Clematidis 4 parts, Radix Paeoniae Rubra 4 parts, perfume Attached 4 parts, Herba Schizonepetae 4 parts, the most positive 4 parts, Caulis Piperis Kadsurae 4 parts, Rhizoma Ligustici 4 parts, Radix Dipsaci 4 parts, Rhizoma Alpiniae Officinarum 4 parts, Radix Angelicae Pubescentis 4 parts, 4 parts of Herba Ephedrae, dry and soft 4 Part, Fructus Forsythiae 4 parts, the Radix Aucklandiae 2 parts, Radix Aconiti Lateralis Preparata 2 parts, 5 parts of Flos Carthami.When preparing female plaster by above compositions, the transdermal agent added is Laurocapram, the mass parts of added laurocapram is 2 parts.
B component: Radix Aconiti 4 parts, Radix Aconiti Kusnezoffii 4 parts, Fructus Gleditsiae Abnormalis 4 parts, Cortex Cinnamomi 4 parts, Rhizoma Arisaematis 4 parts, Fructus Foeniculi 4 parts, Olibanum 4 parts, do not have Medicine 4 parts, Herba Asari 4 parts, Crinis Carbonisatus 30 parts.When preparing sub-plaster by above compositions, the transdermal agent added is laurocapram, added The mass parts entering laurocapram is 1 part.
Use prepared comprise with the use of female plaster and the transdermal patch of sub-plaster for the health of waist relevant disease Time multiple, first by SHENYU acupoint and Weizhong point 75% alcohol disinfecting, mother's plaster being applied to SHENYU acupoint at normal temperatures, sub-plaster is applied ointment or plaster In Weizhong point.Often patch can be applied ointment or plaster 4-7 days continuously.Use without taboo.
Embodiment 2
According to following prescription, weigh appropriate raw material, wherein, component A according to parts by weight respectively: 4 parts of the Radix Rehmanniae, Rhizoma Atractylodis 4 parts, Fructus Aurantii 4 parts, Cortex Acanthopancis 4 parts, Rhizoma Curcumae 4 parts, 4 parts of Semen Persicae, Rhizoma Kaempferiae 4 parts, Radix Angelicae Sinensis 4 parts, Pericarpium Citri Reticulatae 4 parts, Radix Linderae 4 parts, Rhizoma Sparganii 4 parts, big Huang 4 parts, the Radix Polygoni Multiflori 4 parts, Radix Bupleuri 4 parts, Radix Saposhnikoviae 4 parts, Herba Artemisiae Anomalae 4 parts, Rhizoma Chuanxiong 4 parts, Rhizoma Et Radix Notopterygii 4 parts, Radix Clematidis 4 parts, Radix Paeoniae Rubra 4 parts, perfume Attached 4 parts, Herba Schizonepetae 4 parts, the most positive 4 parts, Caulis Piperis Kadsurae 4 parts, Rhizoma Ligustici 4 parts, Radix Dipsaci 4 parts, Rhizoma Alpiniae Officinarum 4 parts, Radix Angelicae Pubescentis 4 parts, 4 parts of Herba Ephedrae, dry and soft 4 Part, Fructus Forsythiae 4 parts, the Radix Aucklandiae 2 parts, Radix Aconiti Lateralis Preparata 2 parts, 5 parts of Flos Carthami.When preparing female plaster by above compositions, the transdermal agent added is Laurocapram, the mass parts of added laurocapram is 2 parts.
B component: Radix Aconiti 4 parts, Radix Aconiti Kusnezoffii 4 parts, Fructus Gleditsiae Abnormalis 4 parts, Cortex Cinnamomi 4 parts, Rhizoma Arisaematis 4 parts, Fructus Foeniculi 4 parts, Olibanum 4 parts, do not have Medicine 4 parts, Herba Asari 4 parts, Crinis Carbonisatus 30 parts.When preparing sub-plaster by above compositions, the transdermal agent added is laurocapram, added The mass parts entering laurocapram is 1 part.
Use prepared comprise with the use of female plaster and the transdermal patch of sub-plaster for the health of cervical region relevant disease Time multiple, first by SHENYU acupoint and pain spot 75% alcohol disinfecting, mother's plaster being applied to SHENYU acupoint at normal temperatures, sub-plaster is applied to Sore place.Often patch can be applied ointment or plaster 4-7 days continuously.Use without taboo.
Embodiment 3
According to following prescription, weigh appropriate raw material, wherein, component A according to parts by weight respectively: 9 parts of the Radix Rehmanniae, Rhizoma Atractylodis 9 parts, Fructus Aurantii 9 parts, Cortex Acanthopancis 9 parts, Rhizoma Curcumae 9 parts, 9 parts of Semen Persicae, Rhizoma Kaempferiae 9 parts, Radix Angelicae Sinensis 9 parts, Pericarpium Citri Reticulatae 9 parts, Radix Linderae 9 parts, Rhizoma Sparganii 9 parts, big Huang 9 parts, the Radix Polygoni Multiflori 9 parts, Radix Bupleuri 9 parts, Radix Saposhnikoviae 9 parts, Herba Artemisiae Anomalae 9 parts, Rhizoma Chuanxiong 9 parts, Rhizoma Et Radix Notopterygii 9 parts, Radix Clematidis 9 parts, Radix Paeoniae Rubra 9 parts, perfume Attached 9 parts, Herba Schizonepetae 9 parts, the most positive 9 parts, Caulis Piperis Kadsurae 9 parts, Rhizoma Ligustici 9 parts, Radix Dipsaci 9 parts, Rhizoma Alpiniae Officinarum 9 parts, Radix Angelicae Pubescentis 9 parts, 9 parts of Herba Ephedrae, dry and soft 9 Part, Fructus Forsythiae 9 parts, the Radix Aucklandiae 6 parts, Radix Aconiti Lateralis Preparata 6 parts, 10 parts of Flos Carthami.When preparing female plaster by above compositions, the transdermal agent added is Laurocapram, the mass parts of added laurocapram is 11 parts.
B component: Radix Aconiti 9 parts, Radix Aconiti Kusnezoffii 9 parts, Fructus Gleditsiae Abnormalis 9 parts, Cortex Cinnamomi 9 parts, Rhizoma Arisaematis 9 parts, Fructus Foeniculi 9 parts, Olibanum 9 parts, do not have Medicine 9 parts, Herba Asari 9 parts, Crinis Carbonisatus 60 parts.When preparing sub-plaster by above compositions, the transdermal agent added is laurocapram, added The mass parts entering laurocapram is 5 parts.
Use prepared comprise with the use of female plaster and the transdermal patch of sub-plaster for the health of waist relevant disease Time multiple, first by SHENYU acupoint and Weizhong point 75% alcohol disinfecting, mother's plaster being applied to SHENYU acupoint at normal temperatures, sub-plaster is applied ointment or plaster In Weizhong point.Often patch can be applied ointment or plaster 4-7 days continuously.Use without taboo.
Embodiment 4
According to following prescription, weigh appropriate raw material, wherein, component A according to parts by weight respectively: 9 parts of the Radix Rehmanniae, Rhizoma Atractylodis 9 parts, Fructus Aurantii 9 parts, Cortex Acanthopancis 9 parts, Rhizoma Curcumae 9 parts, 9 parts of Semen Persicae, Rhizoma Kaempferiae 9 parts, Radix Angelicae Sinensis 9 parts, Pericarpium Citri Reticulatae 9 parts, Radix Linderae 9 parts, Rhizoma Sparganii 9 parts, big Huang 9 parts, the Radix Polygoni Multiflori 9 parts, Radix Bupleuri 9 parts, Radix Saposhnikoviae 9 parts, Herba Artemisiae Anomalae 9 parts, Rhizoma Chuanxiong 9 parts, Rhizoma Et Radix Notopterygii 9 parts, Radix Clematidis 9 parts, Radix Paeoniae Rubra 9 parts, perfume Attached 9 parts, Herba Schizonepetae 9 parts, the most positive 9 parts, Caulis Piperis Kadsurae 9 parts, Rhizoma Ligustici 9 parts, Radix Dipsaci 9 parts, Rhizoma Alpiniae Officinarum 9 parts, Radix Angelicae Pubescentis 9 parts, 9 parts of Herba Ephedrae, dry and soft 9 Part, Fructus Forsythiae 9 parts, the Radix Aucklandiae 6 parts, Radix Aconiti Lateralis Preparata 6 parts, 10 parts of Flos Carthami.When preparing female plaster by above compositions, the transdermal agent added is Laurocapram, the mass parts of added laurocapram is 11 parts.
B component: Radix Aconiti 9 parts, Radix Aconiti Kusnezoffii 9 parts, Fructus Gleditsiae Abnormalis 9 parts, Cortex Cinnamomi 9 parts, Rhizoma Arisaematis 9 parts, Fructus Foeniculi 9 parts, Olibanum 9 parts, do not have Medicine 9 parts, Herba Asari 9 parts, Crinis Carbonisatus 60 parts.When preparing sub-plaster by above compositions, the transdermal agent added is laurocapram, added The mass parts entering laurocapram is 5 parts.
Use prepared comprise with the use of female plaster and the transdermal patch of sub-plaster for the health of cervical region relevant disease Time multiple, first by SHENYU acupoint and pain spot 75% alcohol disinfecting, mother's plaster being applied to SHENYU acupoint at normal temperatures, sub-plaster is applied to Sore place.Often patch can be applied ointment or plaster 4-7 days continuously.Use without taboo.
Embodiment 5
According to following prescription, weigh appropriate raw material, wherein, component A according to parts by weight respectively: 14 parts of the Radix Rehmanniae, Rhizoma Atractylodis 14 Part, Fructus Aurantii 14 parts, Cortex Acanthopancis 14 parts, Rhizoma Curcumae 14 parts, 14 parts of Semen Persicae, Rhizoma Kaempferiae 14 parts, Radix Angelicae Sinensis 14 parts, Pericarpium Citri Reticulatae 14 parts, Radix Linderae 14 parts, Rhizoma Sparganii 14 parts, Radix Et Rhizoma Rhei 14 parts, the Radix Polygoni Multiflori 14 parts, Radix Bupleuri 14 parts, Radix Saposhnikoviae 14 parts, Herba Artemisiae Anomalae 14 parts, Rhizoma Chuanxiong 14 parts, Rhizoma Et Radix Notopterygii 14 parts, prestige Radix Clematidis 14 parts, Radix Paeoniae Rubra 14 parts, Rhizoma Cyperi 14 parts, Herba Schizonepetae 14 parts, the most positive 14 parts, Caulis Piperis Kadsurae 14 parts, Rhizoma Ligustici 14 parts, Radix Dipsaci 14 parts, good Rhizoma Zingiberis Recens 14 parts, Radix Angelicae Pubescentis 14 parts, 14 parts of Herba Ephedrae, dry and soft 14 parts, Fructus Forsythiae 14 parts, the Radix Aucklandiae 10 parts, Radix Aconiti Lateralis Preparata 10 parts, 15 parts of Flos Carthami.More than with During the female plaster of compositions preparation, the transdermal agent added is laurocapram, and the mass parts of added laurocapram is 20 parts.
B component: Radix Aconiti 14 parts, Radix Aconiti Kusnezoffii 14 parts, Fructus Gleditsiae Abnormalis 14 parts, Cortex Cinnamomi 14 parts, Rhizoma Arisaematis 14 parts, Fructus Foeniculi 14 parts, Olibanum 14 parts, Myrrha 14 parts, Herba Asari 14 parts, Crinis Carbonisatus 90 parts.When preparing sub-plaster by above compositions, the transdermal agent added is Laurel Azone, the mass parts of added laurocapram is 10 parts.
Use prepared comprise with the use of female plaster and the transdermal patch of sub-plaster for the health of waist relevant disease Time multiple, first by SHENYU acupoint and Weizhong point 75% alcohol disinfecting, mother's plaster being applied to SHENYU acupoint at normal temperatures, sub-plaster is applied ointment or plaster In Weizhong point.Often patch can be applied ointment or plaster 4-7 days continuously.Use without taboo.
Embodiment 6
According to following prescription, weigh appropriate raw material, wherein, component A according to parts by weight respectively: 14 parts of the Radix Rehmanniae, Rhizoma Atractylodis 14 Part, Fructus Aurantii 14 parts, Cortex Acanthopancis 14 parts, Rhizoma Curcumae 14 parts, 14 parts of Semen Persicae, Rhizoma Kaempferiae 14 parts, Radix Angelicae Sinensis 14 parts, Pericarpium Citri Reticulatae 14 parts, Radix Linderae 14 parts, Rhizoma Sparganii 14 parts, Radix Et Rhizoma Rhei 14 parts, the Radix Polygoni Multiflori 14 parts, Radix Bupleuri 14 parts, Radix Saposhnikoviae 14 parts, Herba Artemisiae Anomalae 14 parts, Rhizoma Chuanxiong 14 parts, Rhizoma Et Radix Notopterygii 14 parts, prestige Radix Clematidis 14 parts, Radix Paeoniae Rubra 14 parts, Rhizoma Cyperi 14 parts, Herba Schizonepetae 14 parts, the most positive 14 parts, Caulis Piperis Kadsurae 14 parts, Rhizoma Ligustici 14 parts, Radix Dipsaci 14 parts, good Rhizoma Zingiberis Recens 14 parts, Radix Angelicae Pubescentis 14 parts, 14 parts of Herba Ephedrae, dry and soft 14 parts, Fructus Forsythiae 14 parts, the Radix Aucklandiae 10 parts, Radix Aconiti Lateralis Preparata 10 parts, 15 parts of Flos Carthami.More than with During the female plaster of compositions preparation, the transdermal agent added is laurocapram, and the mass parts of added laurocapram is 20 parts.
B component: Radix Aconiti 14 parts, Radix Aconiti Kusnezoffii 14 parts, Fructus Gleditsiae Abnormalis 14 parts, Cortex Cinnamomi 14 parts, Rhizoma Arisaematis 14 parts, Fructus Foeniculi 14 parts, Olibanum 14 parts, Myrrha 14 parts, Herba Asari 14 parts, Crinis Carbonisatus 90 parts.When preparing sub-plaster by above compositions, the transdermal agent added is Laurel Azone, the mass parts of added laurocapram is 10 parts.
Use prepared comprise with the use of female plaster and the transdermal patch of sub-plaster for the health of cervical region relevant disease Time multiple, first by SHENYU acupoint and pain spot 75% alcohol disinfecting, mother's plaster being applied to SHENYU acupoint at normal temperatures, sub-plaster is applied to Sore place.Often patch can be applied ointment or plaster 4-7 days continuously.Use without taboo.
The preparation method of the transdermal patch described in any one example of above-described embodiment 1 to 6 comprises the steps:
(1) mixing after each for the Chinese medicine composition in A group component being pulverized, in mixture, boiling 70-100 divides Zhong Hou, is cooled to 24-20 DEG C, filters to obtain the first filtrate;
(2) described first filtrate extraction is obtained the first medicine extraction agent;
(3) in described first medicine extraction agent, add Laurel nitrogen paulownia, be mixed to get the first ointment;
(4) described first ointment is coated in ventilative patch makes female plaster;
(5) mix after in B group, each component of Chinese medicine composition is pulverized, boiling 40-55 minute in mixture After, it is cooled to 20-24 DEG C, filters to obtain the second filtrate;
(6) described second filtrate extraction is obtained the second medicine extraction agent;
(7) in described second medicine extraction agent, add Laurel nitrogen paulownia, be mixed to get the second ointment;
(8) described second ointment is coated on the perverse cloth of water makes sub-plaster.
Ventilative patch in preparation method of the present invention can select elastical cloth, spun laced fabric, the waterproof patch of PU film and grey cotton Any one in fiber blend cloth.
Applicant use of the present invention comprise with the use of female plaster and the transdermal patch of sub-plaster for neck waist During relevant disease rehabilitation, randomly drawing treatment case 200 example, wherein cervical region related disorder patients 87 example, waist is correlated with Disease 113 example, in these cases, effect shows author 179 example, responder 19 example, nonresponder 2 example, and a total of efficiency reaches To 99%.Instant effect good effect after wherein majority of cases clinical practice patient uses.After Patients with Cervical Spondylopathy note, about five hours, Dizziness, headache that blood supply insufficiency causes can be alleviated, and gradually take a turn for the better;The cervical vertebra intercalated disc person of highlighting, applies ointment or plaster five days continuously, pain Pain shape is substantially alleviated;For the waist neck pain caused because of rheumatism, the first note pain relief, often changing a patch all can have bright Aobvious improvement;After pasting the diseases such as hyperostosis survivor, scapulohumeral periarthritis, lumbar muscle strain five days, symptom can significantly be alleviated, and adheres to Apply ointment or plaster and can thoroughly cure;Neck lumbar strain is dampened patient, and a patch gets final product rehabilitation, if any swelling, and after patch 3-5 days can be gradually Detumescence;Stiff neck patient alleviates improvement in 3-5 hour.
Now enumerate model case as follows:
Example 1
Wang, man, 62 years old.Right buttocks pain is radiated 2 years to right thigh and heel, and waist is straight, after stretch the most limited, waist tenderness Inconspicuous, outside right leg, consciousness weakens, and X-ray shows extensive hypertrophy, and Intervertebral space narrows, and is diagnosed as lumbar spondylosis.Use The transdermal patch of the embodiment of the present invention 3, the double movable muscles and bones of period rest, to apply ointment or plaster continuously two months, above symptom all disappears.Extremely The present does not recurs.
Example 2
Liu, man 55 years old.Neck and shoulder pain half a year, channel, physical therapy are without obvious curative effects.Cervical region activity is the most limited.Cervical vertebra 5-6 spine There is tenderness on prominent left side, and RHG is weak.X-ray display cervical vertebra 5-6 saves hypertrophy, its narrowing of intervertebral space.It is diagnosed as cervical spondylosis.Through stopping Breath, physical exercise therapy and the transdermal patch of the use embodiment of the present invention 2, i.e. fully recover for 40 days.Follow up a case by regular visits to 2 years have no recurrence.
Example 3
Zhang, female, 32 years old.Because of its job demand, keep seat for a long time, cause waist to be ached distending pain, time tingle, live Dynamic excessive or chance climate change all increases the weight of the state of an illness, can not bend over to tie the shoelace, be diagnosed as lumbar muscle strain after examination in hospital time serious. Using the transdermal patch of the embodiment of the present invention 1, after a patch, pain substantially alleviates, and after 20 days, above condition of illness all disappears.Follow up a case by regular visits to A year and a half has no recurrence.
Example 4
The Qin, female, 57 years old.Sensation cervical region is cold and cool, and both sides muscle is stiff, neck limitation of activity more than 2 years, and often feels head Dizzy, headache.It is diagnosed as cervical fascia type rheumatism through hospital.Use the transdermal patch of the embodiment of the present invention 4, after one day, dizzy Headache syndromes takes a turn for the better, and applies ointment or plaster continuously two months, and above symptom all disappears.So far do not recur.
Example 5
Chen, man, 64 years old.Accidentally by lumbar sprain in labor service operation, lumbago at once, limitation of activity, take a turn for the better after rest, Activity postemphasis.After three months, the radiation of pain lower limb to the left, is diagnosed as waist 4-5 intervertebral disk hernia on inspection.Through lying up, managing The therapies such as treatment, traction, DeGrain, symptom is day by day aggravated.Use the transdermal patch of the embodiment of the present invention 5, pain after five days Symptom is alleviated, and applies ointment or plaster continuously 50 days, and above condition of illness all disappears.Follow up a case by regular visits to 2 years have no recurrence.
Obviously, the above embodiment of the present invention is only for clearly demonstrating example of the present invention, and is not right The restriction of embodiments of the present invention, for those of ordinary skill in the field, the most also may be used To make other changes in different forms, cannot all of embodiment be given exhaustive here, every belong to this What bright technical scheme was extended out obviously changes or changes the row still in protection scope of the present invention.

Claims (10)

1. a Chinese medicine composition, it is characterised in that described Chinese medicine composition includes two kinds of components being used in conjunction with each other of A and B;
Described component A is made up of the raw material of following weight portion: Radix Rehmanniae 4-14 part, Rhizoma Atractylodis 4-14 part, Fructus Aurantii 4-14 part, Cortex Acanthopancis 4- 14 parts, Rhizoma Curcumae 4-14 part, Semen Persicae 4-14 part, Rhizoma Kaempferiae 4-14 part, Radix Angelicae Sinensis 4-14 part, Pericarpium Citri Reticulatae 4-14 part, Radix Linderae 4-14 part, Rhizoma Sparganii 4- 14 parts, Radix Et Rhizoma Rhei 4-14 part, Radix Polygoni Multiflori 4-14 part, Radix Bupleuri 4-14 part, Radix Saposhnikoviae 4-14 part, Herba Artemisiae Anomalae 4-14 part, Rhizoma Chuanxiong 4-14 part, Rhizoma Et Radix Notopterygii 4-14 part, Radix Clematidis 4-14 part, Radix Paeoniae Rubra 4-14 part, Rhizoma Cyperi 4-14 part, Herba Schizonepetae 4-14 part, white positive 4-14 part, Caulis Piperis Kadsurae 4-14 part, Rhizoma Ligustici 4-14 part, Radix Dipsaci 4-14 part, Rhizoma Alpiniae Officinarum 4-14 part, Radix Angelicae Pubescentis 4-14 part, Herba Ephedrae 4-14 part, dry and soft 4-14 part, Fructus Forsythiae 4-14 part, Radix Aucklandiae 2-10 part, Radix Aconiti Lateralis Preparata 2-10 part, Flos Carthami 5-15 part;
Described B component is made up of the raw material of following weight portion: Radix Aconiti 4-14 part, Radix Aconiti Kusnezoffii 4-14 part, Fructus Gleditsiae Abnormalis 4-14 part, Cortex Cinnamomi 4-14 Part, Rhizoma Arisaematis 4-14 part, Fructus Foeniculi 4-14 part, Olibanum 4-14 part, Myrrha 4-14 part, Herba Asari 4-14 part, Crinis Carbonisatus 30-90 part.
Chinese medicine composition the most according to claim 1, it is characterised in that:
Described component A is made up of the raw material of following weight portion: Radix Rehmanniae 7-11 part, Rhizoma Atractylodis 7-11 part, Fructus Aurantii 7-11 part, Cortex Acanthopancis 7- 11 parts, Rhizoma Curcumae 7-11 part, Semen Persicae 7-11 part, Rhizoma Kaempferiae 7-11 part, Radix Angelicae Sinensis 7-11 part, Pericarpium Citri Reticulatae 7-11 part, Radix Linderae 7-11 part, Rhizoma Sparganii 7- 11 parts, Radix Et Rhizoma Rhei 7-11 part, Radix Polygoni Multiflori 7-11 part, Radix Bupleuri 7-11 part, Radix Saposhnikoviae 7-11 part, Herba Artemisiae Anomalae 7-11 part, Rhizoma Chuanxiong 7-11 part, Rhizoma Et Radix Notopterygii 7-11 part, Radix Clematidis 7-11 part, Radix Paeoniae Rubra 7-11 part, Rhizoma Cyperi 7-11 part, Herba Schizonepetae 7-11 part, white positive 7-11 part, Caulis Piperis Kadsurae 7-11 part, Rhizoma Ligustici 7-11 part, Radix Dipsaci 7-11 part, Rhizoma Alpiniae Officinarum 7-11 part, Radix Angelicae Pubescentis 7-11 part, Herba Ephedrae 7-11 part, dry and soft 7-11 part, Fructus Forsythiae 7-11 part, Radix Aucklandiae 5-7 part, Radix Aconiti Lateralis Preparata 5-7 part, Flos Carthami 8-12 part;
Described B component is made up of the raw material of following weight portion: Radix Aconiti 7-11 part, Radix Aconiti Kusnezoffii 7-11 part, Fructus Gleditsiae Abnormalis 7-11 part, Cortex Cinnamomi 7-11 Part, Rhizoma Arisaematis 7-11 part, Fructus Foeniculi 7-11 part, Olibanum 7-11 part, Myrrha 7-11 part, Herba Asari 7-11 part, Crinis Carbonisatus 50-70 part.
Chinese medicine composition the most according to claim 1, it is characterised in that:
Described component A is made up of the raw material of following weight portion: 9 parts of the Radix Rehmanniae, Rhizoma Atractylodis 9 parts, Fructus Aurantii 9 parts, Cortex Acanthopancis 9 parts, Rhizoma Curcumae 9 Part, 9 parts of Semen Persicae, Rhizoma Kaempferiae 9 parts, Radix Angelicae Sinensis 9 parts, Pericarpium Citri Reticulatae 9 parts, Radix Linderae 9 parts, Rhizoma Sparganii 9 parts, Radix Et Rhizoma Rhei 9 parts, the Radix Polygoni Multiflori 9 parts, Radix Bupleuri 9 parts, anti- Wind 9 parts, Herba Artemisiae Anomalae 9 parts, Rhizoma Chuanxiong 9 parts, Rhizoma Et Radix Notopterygii 9 parts, Radix Clematidis 9 parts, Radix Paeoniae Rubra 9 parts, Rhizoma Cyperi 9 parts, Herba Schizonepetae 9 parts, the most positive 9 parts, sea Radix seu Caulis fici Martinii 9 parts, Rhizoma Ligustici 9 parts, Radix Dipsaci 9 parts, Rhizoma Alpiniae Officinarum 9 parts, Radix Angelicae Pubescentis 9 parts, 9 parts of Herba Ephedrae, dry and soft 9 parts, Fructus Forsythiae 9 parts, the Radix Aucklandiae 6 parts, Radix Aconiti Lateralis Preparata 6 Part, 10 parts of Flos Carthami;
Described B component is made up of the raw material of following weight portion: Radix Aconiti 9 parts, Radix Aconiti Kusnezoffii 9 parts, Fructus Gleditsiae Abnormalis 9 parts, Cortex Cinnamomi 9 parts, Rhizoma Arisaematis 9 Part, Fructus Foeniculi 9 parts, Olibanum 9 parts, Myrrha 9 parts, Herba Asari 9 parts, Crinis Carbonisatus 60 parts.
4. comprise the transdermal patch for neck waist rehabilitation of Chinese medicine composition described in claims 1 to 3 any one, its Be characterised by, described transdermal patch by with the use of female plaster and sub-plaster form, described female plaster is by breathing freely patch and attached Chinese medicine composition in described ventilative patch to constitute, described sub-plaster is by breathing freely patch and being attached in described ventilative patch Chinese medicine composition constitute.
Transdermal patch the most according to claim 4, it is characterised in that on described female plaster, the Chinese medicine composition of attachment is A Component, on described sub-plaster, the Chinese medicine composition of attachment is B component.
Transdermal patch the most according to claim 4, it is characterised in that described ventilative patch is elastical cloth, spun laced fabric, PU film Any one in waterproof patch and grey cotton fiber blend cloth.
7. the preparation method of the transdermal patch as described in claim 4 to 6 any one, it is characterised in that the method include with Lower step:
(1) by 4-14 part Radix Rehmanniae, 4-14 part Rhizoma Atractylodis, 4-14 part Fructus Aurantii, 4-14 part Cortex Acanthopancis, 4-14 part Rhizoma Curcumae, 4-14 part Semen Persicae, 4-14 part Rhizoma Kaempferiae, 4-14 part Radix Angelicae Sinensis, 4-14 part Pericarpium Citri Reticulatae, 4-14 part Radix Linderae, 4-14 part Rhizoma Sparganii, 4-14 part Radix Et Rhizoma Rhei, 4-14 part Radix Polygoni Multiflori, 4-14 part Radix Bupleuri, 4-14 part Radix Saposhnikoviae, 4-14 part Herba Artemisiae Anomalae, 4-14 part Rhizoma Chuanxiong, 4-14 part Rhizoma Et Radix Notopterygii, 4-14 part Radix Clematidis, 4-14 part Radix Paeoniae Rubra, 4-14 part Rhizoma Cyperi, 4-14 part Herba Schizonepetae, 4-14 part are white the most just, 4-14 part Caulis Piperis Kadsurae, 4-14 part Rhizoma Ligustici, 4-14 part Radix Dipsaci, 4-14 Part Rhizoma Alpiniae Officinarum, 4-14 part Radix Angelicae Pubescentis, 4-14 part Herba Ephedrae, 4-14 part are dry and soft, 4-14 part Fructus Forsythiae, 2-10 part Radix Aucklandiae, 2-10 part Radix Aconiti Lateralis Preparata, 5-15 Part Flos Carthami mixes after pulverizing, and in mixture after boiling 70-100 minute, is cooled to 24-20 DEG C, filter first Filtrate;
(2) described first filtrate extraction is obtained the first medicine extraction agent;
(3) in described first medicine extraction agent, add transdermal agent, be mixed to get the first ointment;
(4) described first ointment is coated in ventilative patch makes female plaster;
(5) by 4-14 part Radix Aconiti, 4-14 part Radix Aconiti Kusnezoffii, 4-14 part Fructus Gleditsiae Abnormalis, 4-14 part Cortex Cinnamomi, 4-14 part Rhizoma Arisaematis, 4-14 part Fructus Foeniculi Perfume, 4-14 part Olibanum, 4-14 part Myrrha, 4-14 part Herba Asari, 30-90 part Crinis Carbonisatus mix after pulverizing, boiling in mixture After 40-55 minute, it is cooled to 24-20 DEG C, filters to obtain the second filtrate;
(6) described second filtrate extraction is obtained the second medicine extraction agent;
(7) in described second medicine extraction agent, add transdermal agent, be mixed to get the second ointment;
(8) described second ointment is coated in ventilative patch makes sub-plaster.
Preparation method the most according to claim 7, it is characterised in that described transdermal agent is laurocapram.
Preparation method the most according to claim 8, it is characterised in that the consumption of described laurocapram and the gross weight of each raw material Than for (0.1:10)-(1.5:10), it is preferable that the gross weight of the consumption of described laurocapram and each raw material than for (0.6:10)- (1.0:10)。
10. the using method of the transdermal patch as described in claim 4 to 6 any one, it is characterised in that be correlated with for waist During the rehabilitation of disease, female plaster is applied to SHENYU acupoint, and sub-plaster is applied to Weizhong point;When the rehabilitation of cervical region relevant disease, Female plaster is applied to SHENYU acupoint, and sub-plaster is applied to painful area.
CN201610703109.0A 2016-08-22 2016-08-22 A kind of Chinese medicine composition, the transdermal patch for neck waist rehabilitation comprising this Chinese medicine composition and preparation and application Pending CN106266939A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108567831A (en) * 2018-07-24 2018-09-25 苏石 A kind of Chinese herbs paste, preparation method and its usage
TWI707691B (en) * 2019-03-29 2020-10-21 傅柏舜 Composition for permeating macromolecular drugs through the skin
CN112316083A (en) * 2020-11-13 2021-02-05 山东仁迪生物工程集团有限公司 Collapsed medicinal mud moxibustion for dispelling dampness and expelling cold and application method thereof
CN113209239A (en) * 2021-06-08 2021-08-06 陈奕历 Bone rheumatism plaster for removing blood stasis and relieving pain and preparation method thereof

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CN1329895A (en) * 2000-06-27 2002-01-09 王喜 Exterior-applied ointment for treating hyperosteogeny
CN1621051A (en) * 2003-11-29 2005-06-01 陈景彦 Hyperosteogeny plaster
CN104383436A (en) * 2014-11-03 2015-03-04 贾祥远 Child-mother plaster for treating headache, arthralgia, rhinitis and trachitis by using foamed traditional Chinese medicines
CN104546983A (en) * 2014-12-16 2015-04-29 王如昌 Primary and secondary plaster for treating rheumatism and preparation method thereof

Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
CN1329895A (en) * 2000-06-27 2002-01-09 王喜 Exterior-applied ointment for treating hyperosteogeny
CN1621051A (en) * 2003-11-29 2005-06-01 陈景彦 Hyperosteogeny plaster
CN104383436A (en) * 2014-11-03 2015-03-04 贾祥远 Child-mother plaster for treating headache, arthralgia, rhinitis and trachitis by using foamed traditional Chinese medicines
CN104546983A (en) * 2014-12-16 2015-04-29 王如昌 Primary and secondary plaster for treating rheumatism and preparation method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108567831A (en) * 2018-07-24 2018-09-25 苏石 A kind of Chinese herbs paste, preparation method and its usage
CN108567831B (en) * 2018-07-24 2021-03-23 苏石 Traditional Chinese medicine patch, preparation method and application thereof
TWI707691B (en) * 2019-03-29 2020-10-21 傅柏舜 Composition for permeating macromolecular drugs through the skin
CN112316083A (en) * 2020-11-13 2021-02-05 山东仁迪生物工程集团有限公司 Collapsed medicinal mud moxibustion for dispelling dampness and expelling cold and application method thereof
CN113209239A (en) * 2021-06-08 2021-08-06 陈奕历 Bone rheumatism plaster for removing blood stasis and relieving pain and preparation method thereof

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