KR20200039707A - 건강한 및 병든 심근세포의 성숙 상태를 향상시키기 위한 조성물 및 방법 - Google Patents

건강한 및 병든 심근세포의 성숙 상태를 향상시키기 위한 조성물 및 방법 Download PDF

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KR20200039707A
KR20200039707A KR1020207006161A KR20207006161A KR20200039707A KR 20200039707 A KR20200039707 A KR 20200039707A KR 1020207006161 A KR1020207006161 A KR 1020207006161A KR 20207006161 A KR20207006161 A KR 20207006161A KR 20200039707 A KR20200039707 A KR 20200039707A
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cardiomyocytes
derived
stem cell
cell
cells
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김덕호
제시 마카당당
알렉 에스.티. 스미스
한넬 루오홀라-베이커
제이슨 웨인 미클라스
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유니버시티 오브 워싱톤
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    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells
    • A—HUMAN NECESSITIES
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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KR1020207006161A 2017-08-16 2018-08-16 건강한 및 병든 심근세포의 성숙 상태를 향상시키기 위한 조성물 및 방법 Withdrawn KR20200039707A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762546438P 2017-08-16 2017-08-16
US62/546,438 2017-08-16
PCT/IB2018/056169 WO2019035032A2 (en) 2017-08-16 2018-08-16 COMPOSITIONS AND METHODS FOR ENHANCING THE MATURATION OF HEALTHY AND ILL HEART CARDIOMYCYTES

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KR20200039707A true KR20200039707A (ko) 2020-04-16

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KR1020207006161A Withdrawn KR20200039707A (ko) 2017-08-16 2018-08-16 건강한 및 병든 심근세포의 성숙 상태를 향상시키기 위한 조성물 및 방법

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US (1) US20200224168A1 (https=)
EP (1) EP3664821A4 (https=)
JP (1) JP2020535791A (https=)
KR (1) KR20200039707A (https=)
CN (1) CN111246863A (https=)
WO (1) WO2019035032A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022010049A1 (ko) * 2020-07-09 2022-01-13 주식회사 티앤알바이오팹 인간 전분화능줄기세포 유래 심근세포를 이용한 SARS-CoV-2 바이러스 대상 후보 약물의 심근세포 독성 평가용 조성물 및 이를 이용한 심근세포 독성 평가 방법

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200096610A (ko) * 2017-12-08 2020-08-12 유니버시티 오브 워싱톤 카르디올리핀 리모델링 및 심근세포 성숙을 검출 및 촉진하기 위한 방법 및 조성물 및 미토콘드리아 기능장애를 치료하는 관련 방법
WO2020190939A1 (en) * 2019-03-18 2020-09-24 University Of Washington Methods of promoting cellular maturation with ampk activators
US12173322B2 (en) 2020-12-09 2024-12-24 The University Of Queensland Genome-edited induced pluripotent stem cells, and cells derived therefrom, and uses thereof
JP2022104813A (ja) * 2020-12-29 2022-07-11 アイ ピース，インコーポレイテッド リプログラミング因子を導入された細胞の培養方法
WO2023183371A2 (en) * 2022-03-22 2023-09-28 The Trustees Of Columbia University In The City Of New York Engineered heart tissue model of restrictive cardiomyopathy for drug discovery

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JP2016518117A (ja) * 2013-03-15 2016-06-23 ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャリゼーション 導電性細胞のためのマイクロ電極アレイを含むデバイスおよび方法
WO2014201254A1 (en) * 2013-06-12 2014-12-18 University Of Washington Through Its Center For Commercialization Methods for maturing cardiomyocytes and uses thereof
EP3152300A1 (en) * 2014-06-06 2017-04-12 Pluriomics B.v. Cardiomyocyte maturation
CN106148284A (zh) * 2015-03-23 2016-11-23 苏州博瑞斯坦生物医药有限公司 小分子定向组织和器官再生的多能人类干细胞技术、方法和产品

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022010049A1 (ko) * 2020-07-09 2022-01-13 주식회사 티앤알바이오팹 인간 전분화능줄기세포 유래 심근세포를 이용한 SARS-CoV-2 바이러스 대상 후보 약물의 심근세포 독성 평가용 조성물 및 이를 이용한 심근세포 독성 평가 방법

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Publication number Publication date
WO2019035032A2 (en) 2019-02-21
EP3664821A4 (en) 2021-06-09
CN111246863A (zh) 2020-06-05
WO2019035032A3 (en) 2019-04-25
EP3664821A2 (en) 2020-06-17
JP2020535791A (ja) 2020-12-10
US20200224168A1 (en) 2020-07-16

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