KR20200037851A - 장내 항생제 내성 박테리아를 탈콜론화하기 위한 조성물 및 방법 - Google Patents

장내 항생제 내성 박테리아를 탈콜론화하기 위한 조성물 및 방법 Download PDF

Info

Publication number
KR20200037851A
KR20200037851A KR1020207006802A KR20207006802A KR20200037851A KR 20200037851 A KR20200037851 A KR 20200037851A KR 1020207006802 A KR1020207006802 A KR 1020207006802A KR 20207006802 A KR20207006802 A KR 20207006802A KR 20200037851 A KR20200037851 A KR 20200037851A
Authority
KR
South Korea
Prior art keywords
bacterial
pharmaceutical composition
rrna sequence
bacterial strains
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020207006802A
Other languages
English (en)
Korean (ko)
Inventor
마리나 산티아고
케빈 롤로프스
Original Assignee
핀치 테라퓨틱스, 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 핀치 테라퓨틱스, 인코포레이티드 filed Critical 핀치 테라퓨틱스, 인코포레이티드
Publication of KR20200037851A publication Critical patent/KR20200037851A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/25Shigella (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • C12R1/01
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020207006802A 2017-08-07 2018-08-07 장내 항생제 내성 박테리아를 탈콜론화하기 위한 조성물 및 방법 Ceased KR20200037851A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762542033P 2017-08-07 2017-08-07
US62/542,033 2017-08-07
PCT/US2018/045592 WO2019032572A1 (en) 2017-08-07 2018-08-07 COMPOSITIONS AND METHODS FOR DECOLONIZING ANTIBIOTIC-RESISTANT BACTERIA IN INTESTINES

Publications (1)

Publication Number Publication Date
KR20200037851A true KR20200037851A (ko) 2020-04-09

Family

ID=65272652

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207006802A Ceased KR20200037851A (ko) 2017-08-07 2018-08-07 장내 항생제 내성 박테리아를 탈콜론화하기 위한 조성물 및 방법

Country Status (8)

Country Link
US (2) US20200093870A1 (enExample)
EP (1) EP3665181A4 (enExample)
JP (1) JP2020530493A (enExample)
KR (1) KR20200037851A (enExample)
CN (1) CN111328331A (enExample)
AU (1) AU2018313765A1 (enExample)
CA (1) CA3072029A1 (enExample)
WO (1) WO2019032572A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240072307A (ko) * 2022-11-09 2024-05-24 주식회사 굿바이옴텍 베타-락탐계 항생제 내성 유전자 blaCTX-M-229 및 퀴놀론계 항생제 내성 유전자 qnrS를 갖는 신규한 다제내성 대장균 균주 및 이의 용도

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性t細胞の増殖または集積を誘導する作用を有する組成物
JP6306507B2 (ja) 2011-12-01 2018-04-18 国立大学法人 東京大学 制御性t細胞の増殖または集積を誘導するヒト由来細菌
WO2019032573A1 (en) 2017-08-07 2019-02-14 Finch Therapeutics, Inc. COMPOSITIONS AND METHODS FOR MAINTAINING AND RESTORING A HEALTHY INTESTINAL BARRIER
WO2019079629A1 (en) * 2017-10-18 2019-04-25 Ascus Biosciences, Inc. IMPROVING POULTRY PRODUCTION BY ADMINISTERING A SYNTHETIC BIO-ASSEMBLY OF MICROBES OR PURIFIED STEM THEREFOR
CN113038957A (zh) 2018-04-10 2021-06-25 谢尔塔治疗公司 微生物群
WO2020132098A1 (en) * 2018-12-19 2020-06-25 Healthy Cow Corporation Ready-to-use probiotic compositions and uses thereof
BR112022000875A2 (pt) 2019-07-19 2022-03-29 Finch Therapeutics Holdings Llc Métodos e produtos para tratamento de distúrbios gastrointestinais
EP4021467A4 (en) 2019-08-28 2023-09-13 Xbiome Inc. COMPOSITIONS CONTAINING BACTERIAL SPECIES AND ASSOCIATED METHODS
AU2020354581A1 (en) 2019-09-24 2022-03-03 Prolacta Bioscience, Inc. Compositions and methods for treatment of inflammatory and immune diseases
KR20220108765A (ko) 2019-10-07 2022-08-03 시올타 테라퓨틱스, 인크. 치료용 약학 조성물
GB201915144D0 (en) * 2019-10-18 2019-12-04 Multigerm Uk Entpr Ltd Method of promoting SCFA production by gut microbiota
KR20220101637A (ko) * 2019-10-18 2022-07-19 핀치 테라퓨틱스 홀딩스 엘엘씨 박테리아 대사산물을 대상체에 전달하기 위한 조성물 및 방법
EP3838281A1 (en) * 2019-12-20 2021-06-23 4D Pharma Research Limited Compositions comprising bacterial strains
WO2021231804A2 (en) * 2020-05-13 2021-11-18 President And Fellows Of Harvard College Methods and compositions for suppressing inflammation induced by gut microbes
GB202007452D0 (en) * 2020-05-19 2020-07-01 Microbiotica Ltd Threrapeutic bacterial composition
MX2023001743A (es) 2020-08-14 2023-04-21 Prolacta Bioscience Inc Composiciones de oligosacáridos de la leche humana para usarse con bacterioterapias.
EP4209577A4 (en) * 2020-09-01 2024-06-26 Tohoku University AGENT FOR INCREASING THE CONTENT OF IGA ANTIBODIES IN MILK
EP4223868A4 (en) * 2020-09-30 2025-02-12 National Cancer Center ENHANCEMENT OF THE ANTITUMOR EFFECT OF AN IMMUNE CHECKPOINT INHIBITOR BY ADMINISTRATION OF AN INTESTINAL RUMINOCOCCACEAE BACTERIUM
JP2023550652A (ja) * 2020-11-25 2023-12-04 セレス セラピューティクス インコーポレイテッド 移植片対宿主病を処置するための設計された細菌組成物
US20230149483A1 (en) * 2021-11-12 2023-05-18 Iowa State University Research Foundation, Inc. Short-chain fatty acid use to mitigate antimicrobial resistance and virulence gene transfer in the gut
EP4442264A4 (en) * 2021-12-02 2025-07-16 Univ Tohoku THERAPEUTIC AGENT FOR DIARRHEA AND METHOD FOR TREATING BOVINE DIARRHEA
CN116747227B (zh) * 2023-08-12 2025-07-25 杭州市第一人民医院 泊马度胺在制备抗细菌感染药物中的应用
WO2025093780A1 (en) * 2023-11-05 2025-05-08 Human Biome Institute S.A. The concept of drugs made with the gut microbiota and its components and the method of their administration to obtain effective therapeutic effects
WO2025093778A1 (en) 2023-11-05 2025-05-08 Human Biome Institute S.A. Functional compositions and methods of use thereof in eradication and/or decolonization of antibiotic-resistant bacteria and restoration of healthy microbiota

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6727061B2 (en) * 1997-02-20 2004-04-27 Cabtec, Inc. Methods for identifying species or Shigella and E. coli using operon sequence analysis
JP2003516151A (ja) * 1999-11-29 2003-05-13 エイブイアイ バイオファーマ, インコーポレイテッド 細菌16Sおよび23SrRNAに標的化された、荷電していないアンチセンスオリゴヌクレオチド、ならびにその使用
AU2012225305B2 (en) * 2011-03-09 2017-06-08 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
JP6306507B2 (ja) * 2011-12-01 2018-04-18 国立大学法人 東京大学 制御性t細胞の増殖または集積を誘導するヒト由来細菌
US8921335B2 (en) * 2012-01-31 2014-12-30 The Regents Of The University Of California Oral delivery of nucleic acid-based gene interfering agents by Salmonella
HK1220326A1 (zh) * 2013-03-15 2017-05-05 Seres Therapeutics, Inc. 基於网络微生物组成和方法
PT3003330T (pt) * 2013-06-05 2018-10-10 Rebiotix Inc Terapêutica da restauração da microbiota (trm), composições e processos de fabrico
MA41020A (fr) * 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
GB201519088D0 (en) * 2015-10-28 2015-12-09 Metabogen Ab The use of bacteria formulations
WO2019032573A1 (en) * 2017-08-07 2019-02-14 Finch Therapeutics, Inc. COMPOSITIONS AND METHODS FOR MAINTAINING AND RESTORING A HEALTHY INTESTINAL BARRIER

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240072307A (ko) * 2022-11-09 2024-05-24 주식회사 굿바이옴텍 베타-락탐계 항생제 내성 유전자 blaCTX-M-229 및 퀴놀론계 항생제 내성 유전자 qnrS를 갖는 신규한 다제내성 대장균 균주 및 이의 용도

Also Published As

Publication number Publication date
CA3072029A1 (en) 2019-02-14
JP2020530493A (ja) 2020-10-22
CN111328331A (zh) 2020-06-23
US20200093870A1 (en) 2020-03-26
WO2019032572A1 (en) 2019-02-14
AU2018313765A1 (en) 2020-02-27
US20240307460A1 (en) 2024-09-19
EP3665181A4 (en) 2021-06-09
EP3665181A1 (en) 2020-06-17

Similar Documents

Publication Publication Date Title
KR20200037851A (ko) 장내 항생제 내성 박테리아를 탈콜론화하기 위한 조성물 및 방법
AU2021204574B2 (en) Probiotic and prebiotic compositions, and methods of use thereof for modulation of the microbiome
AU2020202312B2 (en) Compositions and methods for inhibition of pathogenic bacterial growth
KR20200038506A (ko) 건강한 장 장벽을 유지 및 회복시키기 위한 조성물 및 방법
AU2021200287B2 (en) Synergistic bacterial compositions and methods of production and use thereof
KR102426653B1 (ko) 상승작용적 박테리아 조성물, 그리고 이의 제조 방법 및 용도
AU2018338647B2 (en) Novel platforms for co-stimulation, novel car designs and other enhancements for adoptive cellular therapy
KR102869944B1 (ko) 조작된 면역자극성 박테리아 균주 및 이의 용도
AU2014232370B2 (en) Network-based microbial compositions and methods
AU2017235661B2 (en) Oligonucleotide probes and uses thereof
AU2021218133A1 (en) Ammonia-oxidizing nitrosomonas eutropha strain D23
TW202237826A (zh) 基因編輯的自然殺手細胞
AU2014338859B2 (en) Phage therapy of Pseudomonas infections
AU2024201593A1 (en) A genetically modified Lactobacillus and uses thereof
AU2019316556B2 (en) Methods for assessing the risk of developing progressive multifocal leukoencephalopathy caused by john cunningham virus by genetic testing
KR20220004959A (ko) 종양, 종양-상주 면역 세포, 및 종양 미세환경을 콜로니화하기 위해 조작된 면역자극성 박테리아
CN111867608A (zh) 用于痤疮和生物膜的噬菌体治疗
RU2825990C1 (ru) Композиции и способы
RU2804664C2 (ru) Hpv-специфические связывающие молекулы

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20200306

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20210720

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20230703

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20230906

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20230703

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I