KR20190143627A - Hair Cosmetic Composition containing melanoidin and caffeine - Google Patents

Abstract

The present invention relates to a hair cosmetic composition comprising melanoidin and caffeine as active components. More particularly, the present invention relates to a hair cosmetic composition which prevents the formation of gray hair and premature gray hair, and hair loss.

Description

Hair Cosmetic Composition containing melanoidin and caffeine

The present invention relates to a hair cosmetic composition comprising melanoidine and caffeine as an active ingredient, and more specifically, to prevent the production of gray hair and black hair, and to dye the hair and hair previously produced, and to prevent hair loss. It relates to a cosmetic composition.

Healthy hair is deeply related to the production of gray hair or marlin and hair loss in part or all of the scalp, and gray hair or marlin and hair loss are not only a direct reflection of the health of the scalp, but also a beautiful appearance. It is also directly related to

In general, gray hair is produced by aging the cells that produce melanin pigment due to aging. Satch is known to grow into white hair due to excessive production of hydrogen peroxide due to mental stress, heredity, hormone secretion, and the like. If you pull out such gray hair or black hair, it is desirable to dye the part including the black hair because the scalp may be irritated and hair loss may occur.

Generally, gray hair is known to occur with aging, but it is known that gray hair gradually ages due to deterioration of scalp health caused by increased stress and environmental pollution in modern people. Accordingly, the demand for various oxidative hair-related products such as colorants and coloring agents has increased as the demand for dyeing hair or hair beauty increases. However, these oxidative hair-related products contain a large amount of harmful components such as hydrogen peroxide, ammonia and aromatic amines, and it is reported that as the direct irritation to the scalp worsens the condition of the scalp, the age of hair loss is also accelerated. .

On the other hand, the most common cause of hair loss is genetic hair loss, but the recent increase in social stress, hair loss population is gradually increasing due to westernized eating habits such as environmental pollution and instant food, frequent perm and dyeing, and poor scalp management. . The hair loss prevention products known to date are available as commercially available ingredients for promoting blood circulation, inhibiting testosterone action, and strengthening hair root function, but they are not known to have a clear effect in terms of effects. It is a state.

Recently, caffeine has been shown to stimulate the metabolism of hair follicle cells, inhibiting the action of dihydrotestosterone, an active male hormone that stimulates hair follicle growth and shrinks hair follicles. However, too much caffeine content can affect hair follicle cells and cause necrosis, which may result in hair loss. However, the development of high efficacy and safe hair loss inhibitors is insufficient.

Although it is not reported that the production of gray hair and marlin has a direct causal relationship with the hair loss phenomenon, as described above, the hair loss phenomenon is proportional to the use age and demand of oxidative hair-related products such as dyes according to the production of gray hair and marlin. Inhibition of gray hair and marlin is closely related to the inhibition of hair loss. However, the technologies developed to date have little effect of suppressing the occurrence of gray hair and blackfish or at the same time have no effect of inhibiting hair loss, and have a problem of causing secondary scalp irritation by containing a synthetic compound or a metal compound.

Therefore, it is necessary to develop a technology that can prevent hair loss by removing scalp irritation through natural ingredients derived from nature, fundamentally blocking the occurrence of baldness and blackfish, and improving the health of the scalp.

It is an object of the present invention to provide a hair cosmetic composition which essentially inhibits the production of gray hair and marlin.

Another object of the present invention to provide a hair cosmetic composition that can prevent hair loss by improving the health of the scalp worsened by stress and environmental pollution.

Another object of the present invention to provide a hair cosmetic composition comprising a natural ingredient as an active ingredient that does not cause irritation of the scalp.

Another object of the present invention is to provide a hair cosmetic composition capable of inhibiting the production of gray hair and black hair, and at the same time achieving the dual effect of preventing hair loss.

Another object of the present invention is to provide a hair cosmetic composition with a greatly improved ease of use by providing a solution or a dispersed phase of the aqueous phase so that it can be easily applied to the scalp.

Hair cosmetic composition according to the present invention for achieving the above object comprises melanoidine and caffeine as an active ingredient.

In one embodiment of the present invention, the melanoidine may be a water-soluble polymer by Maillard reaction of a sugar and an amino acid.

In one embodiment of the present invention, melanoidine and caffeine may be included in a ratio of 1: 0.01 to 1: 1 by weight.

In one embodiment of the present invention, the melanoidine may be included in 0.001 to 1% by weight of the total weight of the composition.

In one aspect of the present invention, the hair cosmetic composition may further include methionine.

In one aspect of the present invention, the hair cosmetic composition may further include chlorogenic acid.

In one aspect of the present invention, the hair cosmetic composition may further include a C3-C10 polyhydric alcohol.

In one aspect of the invention the hair cosmetic composition may be for hair dye.

In one aspect of the invention the hair cosmetic composition may be for preventing hair loss.

In one aspect of the present invention, the hair cosmetic composition may be for preventing sachets and gray hair.

In one embodiment of the present invention, the hair cosmetic composition further comprises water tonic, hair spray, hair serum, hair essence, hair conditioner, hair lotion, hair cream, hair mousse, hair wax, shampoo, rinse, ampoule, scalp It may be formulated into a pack, nourishing lotion, hair treatment, scalp treatment.

The hair cosmetic composition according to the present invention can be restrained from the roots of gray hair and blackfish to restore a healthy hair condition upon repeated application.

In addition, the hair cosmetic composition according to the present invention has an advantage of preventing hair loss by improving the deteriorated scalp health condition.

In addition, the hair cosmetic composition according to the present invention is safe to include natural ingredients as an active ingredient without including synthetic compounds or irritating harmful substances, and has the advantage of eliminating the irritation of the scalp at its source.

In addition, the hair cosmetic composition according to the present invention has the advantage of inhibiting the production of gray hair and black hair, and at the same time achieve a dual effect of preventing hair loss.

In addition, the hair cosmetic composition according to the present invention is provided as a solution or dispersion phase of the aqueous phase has the advantage that the ease of use is greatly improved.

1 is a coffee extract melanoidin powder according to the present invention.
Figure 2 is a photograph taken for each concentration of the aqueous solution of melanoidin according to the present invention.

DETAILED DESCRIPTION Hereinafter, the present invention will be described in more detail with reference to the accompanying examples or embodiments. However, the following specific examples or examples are only one reference for describing the present invention in detail, but the present invention is not limited thereto and may be implemented in various forms.

Also, unless defined otherwise, all technical and scientific terms have the same meanings as commonly understood by one of ordinary skill in the art to which this invention belongs. The terms used in the description in the present invention are only for effectively describing specific embodiments and are not intended to limit the present invention.

Also, the singular forms used in the specification and the appended claims may be intended to include the plural forms as well, unless the context clearly indicates otherwise.

In addition, unless otherwise defined in the specification and claims, the weight should be the basis, for example, it may be expressed in the form of weight percent or weight ratio.

Hair cosmetic composition according to the present invention relates to a composition comprising melanoidine and caffeine as an active ingredient.

Melanoidin is a high molecular weight polymer derived from sugars and amino acids. Melanoidine can be produced by the reaction of sugars and amino acids at low moisture content and high temperature, and is known to be included in various foods such as coffee, miso, soy sauce and dried fruits.

When the mixture of sugar and amino acid is treated while removing water at a high temperature, melanoidine may be produced as described above, and at this time, the molecular weight, color and water solubility of the melanoidin may be varied depending on the treatment temperature, moisture content, and treatment time. Aqueous solubility may vary.

The sugars may be all monosaccharides, disaccharides, polysaccharides or mixtures thereof or sugar-based compounds. The monosaccharide may be glucose, galactose, fructose, and the like, and the disaccharide may be sucrose, lactulose, lactose, maltose, trehalose, cellobiose, and the like, but this is not limited thereto. Examples of the saccharide compound include a monosaccharide or a compound of a disaccharide in a molecular structure, and examples of the non-limiting example may include a substance in which an aliphatic group is covalently bonded to a monosaccharide or a disaccharide.

The amino acid may be a natural amino acid or an artificial amino acid, for example glycine, alanine, valine, leucine, isoleucine, phenylalanine, tryptophan, methionine, cysteine, proline, serine, threonine, tyrosine, asparagine, glutamine, aspartic acid, Glutamic acid, lysine, arginine, histidine and derivatives thereof, which are examples of amino acids, but are not limited thereto.

The melanoidine is a high molecular weight polymer, the weight average molecular weight may be 1 kDa to 10,000 kDa, specifically 5 kDa to 5,000 kDa, more specifically 5 kDa to 500 kDa, but is not limited thereto.

The melanoidine may preferably be a water soluble polymer, and may be one that is dissolved or solubilized upon contact with water. When water-soluble melanoidine is dissolved in water, the solution may exhibit a transparent or slightly opaque dispersed phase, and the dispersed phase, which remains stable for a long time, should also be interpreted as being within the range of water solubility.

In one embodiment of the present invention, the melanoidine may be a water-soluble polymer by Maillard reaction of a sugar and an amino acid, for example, may have a structure represented by the following formula (1).

[Formula 1]

The Maillard reaction is a kind of aminocarbonyl reaction, a non-enzymatic reaction in which sugars and amino compounds, for example, amino acids, peptides, and proteins react to form a brown substance. Proceed. The Maillard reaction may proceed in a short time by heating, or may proceed for a long time at room temperature to form melanoidin.

Scheme 1

The melanoidin neutralizes the hydrogen peroxide and the active oxygen in the body by showing an excellent antioxidant effect, and gives the effect of preventing the occurrence of gray hair and blackfish due to aging and stress. Specifically, gray hair is produced by the lack of melanin pigment, and the less the melanin pigment, the hair appears white. Melanoidine improves the production of melanin pigment by maintaining the activity of tyrosinase enzymes involved in melanin pigment production. It is very effective in preventing baldness.

In addition, the melanoidine can improve the dyeing effect when used in combination with oxidative hair products such as conventional coloring and coloring agents, and can alleviate the problem of scalp damage inevitably have oxidative hair products. That is, when used with an oxidizing dye or an oxidizing colorant, it is possible to minimize the problems of chemical dyes that damage the scalp, thereby enabling safe dyeing, and because it is a natural ingredient, there is no scalp irritation at all. Can have

In one embodiment of the present invention, the melanoidin can be obtained by the Maillard reaction of sugars and amino acids as described above, and for example, monosaccharides and amino acids, disaccharides and amino acids, monosaccharides and peptides, disaccharides and Various examples, such as reaction of a protein, may be possible.

It can be obtained by heat-treating a mixture of sugars and amino acids as described above to produce melanoidine, but preferably may be derived from natural products containing sugars and amino acids in the raw materials. At this time, the natural product may contain a large amount of sugar and amino acids to obtain a natural product that can obtain the highest amount of melanoidine within a unit time. A preferable example may be beans or green beans, which are preferable in that coffee beans contain a large amount of sugars and amino acids in a unit weight to produce the highest amount of melanoidine in a unit time during heat treatment. Do.

Coffee beans can be obtained by Maillard reaction during the heat treatment of coffee green beans, which contain a large amount of melanoidin. Melanoidine may be extracted by grinding coffee beans, and melanoidine may be a liquid solution obtained after extraction or particles which are spray-dried or lyophilized, but are not limited thereto. Preferably, it may be in the form of lyophilized particles or powder, which is less likely to decay of melanoidine, which is a natural substance, has high solubility in water after lyophilization, and caffeine, which is another active ingredient to maximize physiological activity as a hair cosmetic composition. When used together with the advantage of easy control of the content ratio.

As an example, coffee beans may be used with a moisture content of 5 to 15% by weight, and may be melanoidine by heating for 5 to 120 minutes in the range of 50 ℃ to 250 ℃. In detail, the heat treatment may include a first step of heating the furnace or the drum to a predetermined temperature and then pre-heating the green coffee beans; A second step of removing water contained in the green beans by applying a reduced pressure or a blower to the preheated heating furnace; Inducing a Maillard reaction in green beans; And a fourth step of increasing the temperature to increase the molecular weight of melanoidine.

More specifically, the first step may be performed at a temperature range of 105 ° C. to 120 ° C. for 2 to 5 minutes, and the second step may be performed at a temperature range of 110 ° C. to 120 ° C. for 3 to 7 minutes. have. The heat treatment temperature and time of the first step and the second step are illustrated as a non-limiting example, the heat treatment temperature and time is not limited to the numerical range in the range to achieve the purpose of preheating and removing moisture of the coffee beans.

The third step may be performed for 5 minutes to 10 minutes in the temperature range of 115 ℃ to 125 ℃, during the heat treatment at the temperature and time promotes the Maillard reaction between sugars and amino acids in the coffee beans during the heat treatment, so that a number of melanoidine precursors Can be generated. The fourth step may include performing a heat treatment for 5 minutes to 10 minutes at a temperature range of 135 ° C to 145 ° C, followed by heat treatment for 2 minutes to 5 minutes at a temperature range of 140 ° C to 150 ° C. It may be desirable to increase the molecular weight and the amount of the melanoidine through the heat treatment of the two steps. More preferably, after the third step is completed, a part or all of the heat-treated coffee beans may be ground and mixed to maximize the specific surface area of the heat-treated coffee beans and effectively induce evaporation of residual moisture. The heat-treated coffee green beans particles pulverized through the additional grinding step may then maintain the heat treatment temperature evenly to the inside of the particles in the fourth step, and the Maillard reaction occurs throughout the particles, so that the molecular weight of melanoidine is kept relatively constant and thus the molecular weight distribution. (polydispersity index) is constant, even though the high molecular weight has the advantage that the water solubility can be improved.

Optionally, after completion of the fourth step, a fifth step of ripening the coffee beans for 5 to 10 minutes in a temperature range 20 ° C to 30 ° C lower than the heat treatment temperature of the fourth step.

Melanoidine can be obtained through a conventional extraction process using the coffee beans heat-treated through the above steps. For example, the coffee beans may be ground and mixed with distilled water to extract melanoidine. For example, but not limited thereto, the solid extract may be recovered by stirring and warming with high temperature distilled water at 50 ° C. to 100 ° C. to remove solids. Can be. As another example, an extract obtained by grinding coffee beans mixed with hot distilled water may be recovered, which is an example of a conventional extraction process, and is not limited to the exemplary method.

Also optionally after the extraction process, it may further include a filter and purification step of the coffee bean extract. For example, the coffee bean extract may be permeated under a reduced pressure using a filter membrane to remove solid insolubles and to obtain purified melanoidine using a dialysis membrane, but this is only an example of purification and is not limited to the above purification method. Do not. By further comprising the purification step to obtain a high molecular weight melanoidine distribution of relatively constant molecular weight, when the melanoidine is dissolved in water to obtain a melanoidine aqueous solution having high phase stability without high precipitation even during long-term storage Can be.

The obtained coffee bean extract may be in liquid form, or may be obtained as melanoidin in the form of spray-dried or lyophilized particles, preferably in lyophilized particles or powder form.

In one embodiment of the present invention, the melanoidin may be included in 0.001 to 1% by weight, specifically 0.005 to 0.5% by weight, more specifically 0.01 to 0.1% by weight of the total weight of the composition, but is not limited thereto. Melanoidine in the above range is excellent in inhibiting the production of gray hair and grayfish while showing an excellent antioxidant effect, it is possible to maintain a stable aqueous phase without precipitation or phase separation in the aqueous solution. In particular, the water-soluble melanoidin obtained under the heat treatment conditions as described above is a high molecular weight water-soluble polymer, but the hydrophobic domain and the hydrophilic domain are formed during the polymerization process, so that the polymer can have an appropriate balance of hydrophobicity and hydrophilicity. Accordingly, melanoidine may have characteristics of a carrier capable of partially solubilizing the oil-soluble component through the formed hydrophobic domain, and has excellent advantages of penetration and absorption through the scalp and the pores of the scalp.

The melanoidine may have amphiphilicity by including the hydrophobic and hydrophilic properties in the polymer at the same time, preferably have the structure of the association.

The caffeine has been found to stimulate hair follicle growth by stimulating the metabolism of hair follicle cells as a phosphodiestearase inhibitor in relation to hair growth. It also confers the effect of inhibiting the action of testosterone, a testosterone that causes hair loss by atrophy of hair follicles, and dihydrotestosterone, an active male hormone produced therefrom.

Caffeine is known as an effective ingredient that inhibits hair loss, but has a poor solubility in water, and low solubility at low temperatures makes it difficult to contain a large amount in an aqueous solution composition. In particular, due to the nature of the cosmetic composition, the storage of the composition at a low temperature in order to prevent corruption or chemical denaturation may occur precipitation of the active ingredient in the formulation, this precipitation phenomenon not only shows a significant decrease in the biological activity effect, It has been a problem that is inhibited.

However, since caffeine is included in the composition together with the water-soluble melanoidine as an active ingredient, the caffeine having hydrophobicity is stably solubilized by the water-soluble melanoidine so that the caffeine can be stably contained in the composition without an increase in turbidity due to precipitation or precipitation. .

In addition, since the melanoidine and caffeine are included together as an active ingredient in the hair cosmetic composition, the melanoidine and caffeine can simultaneously exhibit a physiological activity effect is preferable. That is, the water-soluble melanoidin solubilizes caffeine stably by appropriate hydrophobicity, so that melanoidin and caffeine can be effectively absorbed into the scalp and scalp pores, and each absorbed component can neutralize hydrogen peroxide and active oxygen by powerful antioxidant effect. It can maintain the enzymatic activity of tyrosinase and at the same time activate hair follicle cells and strengthen hair roots to prevent hair loss.

That is, by using a high molecular weight water-soluble melanoidine and a low molecular weight hydrophobic caffeine, the solubility in water and the absorption of the scalp and the scalp into the pores can be significantly improved, which can result in a markedly improved hair loss prevention effect and the suppression of gray hair and sac.

When caffeine alone is used as an active ingredient for preventing hair loss, treatment with a low content of caffeine-containing composition has no or minimal hair loss prevention effect, and when treated with a high content of caffeine-containing composition, it acts as a cause of hair loss by necrosis of hair follicle cells. There was a problem. However, by including a high molecular weight water-soluble melanoidine and a hydrophobic caffeine according to the present invention, even if it contains a low content of caffeine may have a high hair loss prevention effect by interaction with the water-soluble melanoidin, the mechanism is not clear, but does not contain caffeine By including caffeine as compared to the melanoidine alone composition does not have more improved gray hair and sach inhibiting effect.

In one aspect of the invention, the melanoidine and caffeine may be 1: 0.01 to 1: 1, specifically 1: 0.05 to 1: 0.5 by weight. Preferably melanoidine and caffeine may be included in the composition in a ratio of 1: 0.05 to 1: 0.1 by weight. By having a melanoidine and caffeine weight ratio in the above range, the melanoidine in the hair cosmetic composition easily solubilizes caffeine, and the two components can more effectively interact with each other to have an excellent hair loss prevention effect and gray hair and anti-scarring effect.

In one aspect of the invention the composition may further comprise methionine. Methionine is one of the amino acids that form hair, and it is effective in preventing hair loss by affecting hair follicles, promoting hair growth, and keeping the scalp and hair healthy. Methionine may have an effect of preventing hair loss by being absorbed into the scalp, but may be effective in inhibiting the occurrence of gray hair and blackfish by promoting the expression of tyrosinase.

Specifically, tyrosinase is a major enzyme involved in melanin production and is known to regulate the expression of pigments by regulating the activity of the tyrosinase. By maintaining the activity of tyrosinase, it is known that quinones are produced by enzymatic reactions and quinones are converted to melanin. This mechanism of action is also closely related to hair depigmentation, ie the production of gray hair and swordfish. The production of gray hair and marlin has been associated with a decrease in melanin pigmentation in hair follicles and a decrease in melanocyte populations in hair follicles.

Typically, the pigmentation mechanism in the skin is known that melanocytes express tyrosinase and that melanin produced by tyrosinase is transferred to keratinocytes so that pigments are deposited on the skin by melanin granules. Similarly, healthy hair follicles contain melanocytes in the outer root sheath (ORS), while fewer melanocytes are found in the outer hair follicles of hair follicles where baldness or gray hair occurs. In other words, the increase in gray hair and marlin strongly suggests that the number of melanocytes present in hair follicles and the activity of tyrosinase are closely related.

In particular, methionine located at the active site of tyrosinase by hydrogen peroxide may be oxidized to methionine sulfoxide, and the enzyme activity may disappear. When methionine is delivered to hair follicles, methionine reacts with hydrogen peroxide competitively against tyrosinase and preferentially oxidizes, thereby reducing the loss of activity of tyrosinase. By maintaining the activity of tyrosinase by the addition of methionine as described above, melanocytes can stably produce pigments, and can suppress the occurrence of gray and gray hair.

The methionine may be included in 10 to 200% by weight, specifically 50 to 150% by weight relative to the total weight of melanoidine in the hair cosmetic composition. Methionine is a water-soluble amino acid, so it does not need to be solubilized in an aqueous solution, but can be enhanced in the hair follicle by being contained in the composition with a melanoidine derived from a sugar and an amino acid. It may be desirable.

In one aspect of the invention the composition may further comprise chlorogenic acid. Chlorogenic acid is a polyphenol contained in plant extracts, and has an excellent antioxidant effect, preventing the damage caused by free radicals of hair and giving the effect of suppressing the occurrence of gray hair and blackfish. The content of the chlorogenic acid may be included in 1 to 50% by weight, specifically 5 to 20% by weight relative to the total weight of melanoidine in the hair cosmetic composition, but is not limited thereto. As the chlorogenic acid is included in the above range, it can neutralize hydrogen peroxide and active oxygen by giving synergistic effect to the antioxidant effect of melanoidin, and can be very effective in suppressing the occurrence of gray hair and blackfish by maintaining the activity of catalase and tyrosinase enzymes. .

Hair cosmetic composition according to an aspect of the present invention may further include a C3-C10 polyhydric alcohol, and may be used without limitation as long as it is a polyhydric alcohol commonly used in the art. As a non-limiting example, the C3-C10 polyhydric alcohol may include 2 to 8 hydroxyl groups in one molecule, and may be a material having high solubility in water. The polyhydric alcohol is specifically, for example, erythritol, xylitol, sorbitol, malitol, glycol, glycerin, 1,2-propanediol, 1,3-propanediol, 1,3-butylene glycol, 1,2-pentanediol , 1,2-hexanediol, 1,2-octanediol, dipropylene glycol may be any one or a mixture of two or more, but this is only an example and is not limited thereto. The C3-C10 polyhydric alcohol may be included in 0.1 to 10% by weight, specifically 1 to 5% by weight of the total weight of the hair cosmetic composition, but is not limited thereto. Preferably, the polyhydric alcohol may be a C4-C8 polyhydric alcohol, more preferably, using 1,2-hexanediol as the polyhydric alcohol may impart an antiseptic effect.

In one aspect of the invention the hair cosmetic composition may be for hair dye. Specifically, oxidative hair products, such as conventional coloring and coloring agents, contain a large amount of harmful components such as hydrogen peroxide, ammonia and aromatic amines, and when applied to the hair can cause direct irritation to the scalp. However, as the hair dye cosmetic composition includes melanoidine and caffeine, it can alleviate the problem of scalp damage that oxidative hair products inevitably have. In other words, when used with an oxidizing dye or an oxidizing colorant, it is possible to minimize the problems of chemical dyes that damage the scalp, thereby enabling safe dyeing. Since melanoidine and caffeine are naturally derived ingredients, there is no scalp irritation at all and color development is also improved. You can.

Dyeing or coloring agents can induce hair dyeing and coloration in a short period of time through chemical reactions in the hair, but is not an essential way to prevent hair decolorization, the hair cosmetic composition according to the present invention is used in combination with a dyeing or coloring agent In this case, a more advantageous effect can be obtained. In other words, the hair is dyed and colored, and as described above, melanoidin and caffeine are absorbed into the hair follicles to suppress the production of gray hair and marlin, and the oxidative stress caused by the contact of the coloring and coloring agents with the scalp and hair follicles is also remarkable. Can be reduced.

Dyeing agents and coloring agents can be used without limitation as long as it is a known composition, non-limiting examples of dyeing agents may include ammonia, hydrogen peroxide, aromatic amine-based compounds, etc. may be included in the first agent and the second agent, if necessary have. Coloring agents may include a phenolic compound, a heteroaryl compound, an aromatic amine compound, and the like, but this is only an example and is not limited thereto.

Specifically, the dyeing method may be carried out by applying a known dyeing or coloring agent composition to the hair and left for 1 to 30 minutes, depending on the components and content of the dyeing or coloring agent composition, the dyeing may be performed even with a short standing time of 1 to 15 minutes. Effectively, but this is only an example and not limited thereto. The method of application is also not particularly limited and may be applied to the hair separately before or after the treatment of the colorant or colorant, or may be applied to the hair together with the colorant or colorant. For example, the hair cosmetic composition according to the present invention may be mixed with a known dyeing or coloring agent composition, and then a method such as dipping hair or spraying the composition on the hair may be used.

In a more specific aspect according to the present invention, the hair dye cosmetic composition is selected from surfactants, pH adjusters, direct dyes, swelling agents, buffers, preservatives, flavoring agents, humectants, viscosity regulators, aliphatic alcohols and vitamins, etc. It may further include any one or two or more.

The surfactant may be used without particular limitation as long as it is commonly used in the art, and for example, cationic surfactants, anionic surfactants, nonionic surfactants, amphoteric surfactants, or mixtures thereof. Among the known surfactants, it can be appropriately selected and used to achieve the effect of the present invention. More specifically, for example, the surfactants include alkyl sulfates, alkyl ether sulfates, sodium alkane sulfonates, alkyl trimethyl ammonium halides, alkyl pyridinium halides, alkyl imimidazole salt halides, polyethylene oxide surfactants, and polyvinyl water-soluble polymers. And one or two selected from, but not limited to, sodium dodecyl sulfate, sodium octylbenzene sulfonate, sodium dodecylbenzene sulfonate, ammonium lauryl sulfate, triton X-100, polyvinylpyrrolidone, and the like. The mixture may be, but is not limited thereto.

The pH adjusting agent is to give a pH control of the composition is not particularly limited as long as it is commonly used in the art, any one or two or more selected from sodium hydroxide, potassium hydroxide, triethanolamine, citric acid and sodium citrate, etc. It may be a mixture, but is not limited thereto.

The direct dye may be used without particular limitation as long as it is commonly used in the art, but vegetable dyes such as henna or indigo may be used, but are not limited thereto.

The swelling agent can be used without particular limitation as long as it is commonly used in the art, any one or two or more selected from urea, thiourea, urea peroxide, polyoxymethylene urea, hydroxyethyl urea, ammonia and salts thereof It may be a mixture, but is not limited thereto.

The buffer may be used without particular limitation as long as it is commonly used in the art, but may be any one or a mixture of two or more selected from salicylic acid, sodium salicylate, lactic acid and sodium lactate, but is not limited thereto. .

The preservative may be used without particular limitation as long as it is commonly used in the art, and may include any one or a mixture of two or more selected from methyl paraben, propyl paraben, phenoxyethanol, methyl paraoxybenzoate, and paraoxybenzoate. The fragrance may be used without particular limitation as long as it is conventionally used in the art, and may be selected from natural or artificial synthetic fragrances.

The moisturizing agent may be used without particular limitation as long as it is commonly used in the art, and includes, but is not limited to, polymeric glycols such as polyethylene glycol; Low molecular weight glycols such as glycerol, propylene glycol and butanediol; And components commonly used, such as oils.

In one aspect of the invention the hair cosmetic composition may be for preventing hair loss.

In the cosmetic composition for preventing hair loss according to an aspect of the present invention, the composition may further include a component that is effective in preventing hair loss. For example, tocopherol and its derivatives, nicotinic acid and its derivatives, natural oils, blood circulation promoters and the like may be further included one or two or more. Preferably, it may be a natural oil, and the natural oil may further include, but is not limited to, any one or two or more selected from camellia oil, cardamom oil, cypress leaf oil, peppermint oil, and the like.

The natural oils are effective in preventing hair loss, but because of their low solubility in water, they have to be used with surfactants solubilized or included in emulsion formulations. However, melanoidine is a high molecular weight water soluble polymer, but by including an appropriate hydrophobic domain and a hydrophilic domain in the polymer, it can have a surface active ability to partially solubilize the oil soluble component, thereby stably solubilizing the natural oil. As the natural oil is solubilized stably by the melanoidine, the melanoidine may have the properties of a carrier for the natural oil, and exhibit excellent hair loss prevention effect by effectively absorbing the natural oil through the scalp and the pores of the scalp.

The content of the natural oil in the composition may be included in 1 to 10% by weight, specifically 2 to 5% by weight relative to the total weight of melanoidine, when included in the range can be solubilized natural oil without additional surfactant, long-term storage In addition, since turbidity increase and precipitation do not occur, it may be preferable.

In one aspect of the present invention, the hair cosmetic composition may be for preventing sachets and gray hair.

In the hair cosmetic composition for preventing black hair and gray hair according to an aspect of the present invention, the composition may further include a component that has an effect on the prevention of gray hair and black hair, and specifically, for example, green tea extract, black tea as the component. Extracts, peony extracts, Astragalus extract, vitamin C and derivatives thereof, any one selected from antioxidants such as erythorbic acid, dibutyl hydroxytoluene, or mixtures thereof, but is not limited thereto. The antioxidant may be included in 0.01 to 10% by weight, specifically 0.05 to 5% by weight of the total weight of the anti-atch hair cosmetic composition. When the antioxidant is included in the above range it is preferable because it can further improve the anti-atch effect of the hair cosmetic composition according to the present invention.

In one aspect of the invention the hair cosmetic composition may be an aqueous or aqueous cosmetic composition further comprises water. Specific examples include hair tonic, hair spray, hair serum, hair essence, hair conditioner, hair lotion, hair cream, hair mousse, hair wax, shampoo, conditioner, ampoule, scalp pack, nutrition lotion, hair treatment, scalp treatment It may be formulated. In detail, the hair cosmetic composition according to the present invention can be added to a conventional cosmetic formulation including water, and the present invention can provide a hair product comprising the composition. More specifically, the amount of the cosmetic composition for hair is not particularly limited, but may be added in an amount of 1 to 50 parts by weight based on 100 parts by weight of the formulation including water.

Hereinafter, the present invention will be described in more detail with reference to Examples and Comparative Examples. However, the following Examples and Comparative Examples are only examples for explaining the present invention in more detail, the present invention is not limited by the following Examples and Comparative Examples.

[Production Example 1]

Put 10 Kg of Arabica coffee beans into the oven preheated to 105 ℃, heat-treat for 3 minutes, heat up at a rate of 5 ℃ / min, and blow air at 115 ℃ for 5 minutes to cause cracks in green beans, Removed. Thereafter, the temperature was raised at a rate of 5 ° C./min, heat treated at 120 ° C. for 7 minutes, and then ground in an oven at an average temperature of about 1 mm with an average particle diameter. The ground coffee beans were heated at a rate of 10 ° C./min, heat treated for 7 minutes in an oven at 140 ° C., and heated at a rate of 10 ° C./min, and heat treated for 3 minutes in an oven at 145 ° C. The coffee beans after the heat treatment were again ground to an average particle diameter of about 0.5 mm using a grinder, added to 10 liters of hot water at 100 ° C., and extracted three times for 1 hour to obtain 2.4 Kg of coffee extract.

[Production Example 2]

1 Kg of the coffee extract prepared in Preparation Example 1 was added to 50 L of water at 70 ° C, and stirred for 10 minutes to dissolve. The dissolved coffee extract was cooled to 10 ° C., centrifuged at 10,000 rpm for 2 minutes to remove precipitates, and the filter was repeated three times under reduced pressure using a vacuum pump using a nylon filter membrane having a size of 0.45 micropores. The filtered coffee extract was dialyzed in distilled water for 3 days using a dialysis membrane (molecular weight: 12-14 kDa) and then lyophilized to obtain 250 g of brown melanoidine powder of FIG.

[Examples 1-3]

The compositions of Examples 1 to 3 were prepared by combining the melanoidines obtained from Preparation Example 2 with the components shown in Table 1 below. The amount of purified water was added to the balance so that the total weight was 100 g.

Example 4

Example 2 was mixed in the same manner as in Table 1, except that the peppermint oil was solubilized by mixing for 2 minutes and sonication.

Comparative Example 1

Except for the caffeine component in Example 1 was the same.

Comparative Example 2

Except for the melanoidine component in Example 1 it was carried out in the same manner.

Example 1 Example 2 Example 3 Example 4 Comparative Example 1 Comparative Example 2 Melanoidine 1 g 1 g 1 g 1 g One - Caffeine 0.1g 0.1g 0.1g 0.1g - 0.1g Methionine - 1 g 1 g 1 g - - Chlorogenic acid - - 0.15 g - - - Peppermint Oil - - - 0.02 g - - Panthenol 0.1g 0.1g 0.1g 0.1g 0.1g 0.1g 1,2-hexanediol 2.0 g 2.0 g 2.0 g 2.0 g 2.0 g 2.0 g Purified water balance balance balance balance balance balance

Test Example 1 Hair Growth Effect Test

A hair growth effect test was conducted to test the hair loss prevention effect. The hair growth effect test was carried out by removing the hair at the back region using a 7-week-old mouse (C57BL / 6, female), and divided into 10 groups per material group. After the adaptation period of one day, the composition of Examples and Comparative Examples was applied to the hair removal site of the mouse from the next day once a day, 100 μl for 21 days. The degree of hair growth was visually determined, and the ratio of the area in which the newborn hair was grown to the area from which hair was removed was shown in Table 2 below.

sample Effective area (%) Control 21 Example 1 48 Example 2 49 Example 3 58 Example 4 75 Comparative Example 1 24 Comparative Example 2 36

As shown in Table 2, Examples 1 to 4 containing melanoidine and caffeine as active ingredients in the present invention had a significant hair growth promoting effect compared to the comparative example containing only melanoidine or caffeine. Specifically, an excellent level of hair growth was observed in Example 3 containing chlorogenic acid, and a higher level of hair growth was observed in Example 4 containing solubilized peppermint oil than Example 3 containing chlorogenic acid.

The hair growth effect is due to the synergistic action of melanoidin and caffeine, especially in the case of peppermint oil that is not dissolved in water, melanoidin effectively solubilizes the oil and transfers it into hair follicles, which is higher than peppermint oil alone. Means that the hair growth effect has been brought. No unusual skin irritation was found in all treatment groups during the 21 day trial.

Test Example 2 Satch Improvement Test

In the head of ten males in their 40s with mixed hair all over the head, the observation site was specified in the range of 1 cm × 1 cm, and the compositions of Examples and Comparative Examples were applied to the site twice a day by 1.0 ml. As a result of observing the condition of the hair after 30 days, it was confirmed that the proportion of white hair was reduced and the proportion of black hair was increased in Examples 1 to 4, and in particular, it was observed that the proportion of black hair was the highest in Example 3. In Comparative Example 1, the proportion of gray hair was slightly decreased, but in Comparative Example 2, the proportion of gray hair was slightly increased.

Claims (11)

Hair cosmetic composition comprising melanoidine and caffeine as an active ingredient. The method of claim 1,
The melanoidine is a hair cosmetic composition is a water-soluble polymer by the Maillard reaction of sugars and amino acids. The method of claim 1,
The melanoidine and caffeine in the hair cosmetic composition comprising a ratio of 1: 0.01 to 1: 1 by weight. The method of claim 1,
The melanoidine is a hair cosmetic composition comprising 0.001 to 1% by weight of the total weight of the composition. The method of claim 1,
The composition is a hair cosmetic composition further comprises methionine. The method of claim 1,
The composition is a hair cosmetic composition further comprises chlorogenic acid (chlorogenic acid). The method of claim 1,
The composition further comprises a C3-C10 polyhydric alcohol hair cosmetic composition. The method of claim 1,
The composition is a hair cosmetic composition for hair dye. The method of claim 1,
The composition is a hair cosmetic composition for preventing hair loss. The method of claim 1,
The composition is a hair cosmetic composition for prevention of gray hair and gray hair. The method of claim 1,
The composition further comprises water tonic, hair spray, hair serum, hair essence, hair conditioner, hair lotion, hair cream, hair mousse, hair wax, shampoo, rinse, ampoule, scalp pack, nourishing lotion, hair treatment Hair cosmetic composition is formulated as a scalp treatment.

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