KR20190114010A - 주사비 징후들의 치료용 옥시메타졸린의 약학 크림 조성물들 - Google Patents

주사비 징후들의 치료용 옥시메타졸린의 약학 크림 조성물들 Download PDF

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Publication number
KR20190114010A
KR20190114010A KR1020197028285A KR20197028285A KR20190114010A KR 20190114010 A KR20190114010 A KR 20190114010A KR 1020197028285 A KR1020197028285 A KR 1020197028285A KR 20197028285 A KR20197028285 A KR 20197028285A KR 20190114010 A KR20190114010 A KR 20190114010A
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KR
South Korea
Prior art keywords
cream
oxymethazolin
certain embodiments
pharmaceutically acceptable
skin
Prior art date
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KR1020197028285A
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English (en)
Korean (ko)
Inventor
스튜어트 디. 쉔러
크리스토퍼 포왈라
Original Assignee
어클라리스 쎄라퓨틱스, 인코포레이티드
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Publication of KR20190114010A publication Critical patent/KR20190114010A/ko
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
KR1020197028285A 2011-02-15 2012-02-14 주사비 징후들의 치료용 옥시메타졸린의 약학 크림 조성물들 Withdrawn KR20190114010A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161443210P 2011-02-15 2011-02-15
US61/443,210 2011-02-15
PCT/US2012/025068 WO2012112566A1 (en) 2011-02-15 2012-02-14 Pharmaceutical cream compositions of oxymetazoline for treating symptoms of rosacea

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020137024232A Division KR102058756B1 (ko) 2011-02-15 2012-02-14 주사비 징후들의 치료용 옥시메타졸린의 약학 크림 조성물들

Publications (1)

Publication Number Publication Date
KR20190114010A true KR20190114010A (ko) 2019-10-08

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020197028285A Withdrawn KR20190114010A (ko) 2011-02-15 2012-02-14 주사비 징후들의 치료용 옥시메타졸린의 약학 크림 조성물들
KR1020137024232A Active KR102058756B1 (ko) 2011-02-15 2012-02-14 주사비 징후들의 치료용 옥시메타졸린의 약학 크림 조성물들

Family Applications After (1)

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KR1020137024232A Active KR102058756B1 (ko) 2011-02-15 2012-02-14 주사비 징후들의 치료용 옥시메타졸린의 약학 크림 조성물들

Country Status (11)

Country Link
US (4) US20120208858A1 (enExample)
EP (2) EP2675449B1 (enExample)
JP (3) JP6225030B2 (enExample)
KR (2) KR20190114010A (enExample)
CN (2) CN107007546A (enExample)
AU (3) AU2012217858A1 (enExample)
BR (1) BR112013020770A2 (enExample)
CA (1) CA2827373C (enExample)
ES (1) ES2742273T3 (enExample)
RU (1) RU2648439C2 (enExample)
WO (1) WO2012112566A1 (enExample)

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Also Published As

Publication number Publication date
JP6389534B2 (ja) 2018-09-12
JP2017066162A (ja) 2017-04-06
CN103458897A (zh) 2013-12-18
KR102058756B1 (ko) 2020-01-22
AU2017202726A1 (en) 2017-05-18
AU2019203993B2 (en) 2020-05-28
RU2013141845A (ru) 2015-03-27
ES2742273T3 (es) 2020-02-13
AU2019203993A1 (en) 2019-06-27
CN107007546A (zh) 2017-08-04
US20200276108A1 (en) 2020-09-03
US20140113947A1 (en) 2014-04-24
JP2018193399A (ja) 2018-12-06
EP2675449B1 (en) 2019-04-24
US11541000B2 (en) 2023-01-03
JP6225030B2 (ja) 2017-11-01
WO2012112566A1 (en) 2012-08-23
CA2827373C (en) 2019-05-14
RU2648439C2 (ru) 2018-03-26
BR112013020770A2 (pt) 2019-08-27
US20190167566A1 (en) 2019-06-06
JP2014505733A (ja) 2014-03-06
EP3578178A1 (en) 2019-12-11
KR20140020912A (ko) 2014-02-19
AU2012217858A1 (en) 2013-09-05
US20120208858A1 (en) 2012-08-16
EP2675449A1 (en) 2013-12-25
AU2017202726B2 (en) 2019-03-07
CA2827373A1 (en) 2012-08-23

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A107 Divisional application of patent
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20190926

Application number text: 1020137024232

Filing date: 20130913

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid