KR20190063115A - A chinese medicine for gastric ulcer treatment - Google Patents

A chinese medicine for gastric ulcer treatment Download PDF

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KR20190063115A
KR20190063115A KR1020170161964A KR20170161964A KR20190063115A KR 20190063115 A KR20190063115 A KR 20190063115A KR 1020170161964 A KR1020170161964 A KR 1020170161964A KR 20170161964 A KR20170161964 A KR 20170161964A KR 20190063115 A KR20190063115 A KR 20190063115A
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gastric ulcer
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yam
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밍츄 리
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밍츄 리
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/754Evodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • Y10S514/925

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Abstract

The present invention provides a Chinese medicine for treating gastric ulcers. The Chinese medicine provides not only long-term properties of regular medicines but also excellent effects for alleviating post-meal stomach pain. The Chinese medicine comprises, as main ingredients, Cyperus rotundus and Fructus evodiae, and combines the benefits of traditional medicine with products of modern pharmacological studies. In particular, the Chinese medicine comprises: 20-40 parts by weight of Cyperus rotundus; 10-20 parts by weight of Fructus evodiae; 6-8 parts by weight of Coptis chinensis; 8-12 parts by weight of Fructus aurantii; 4-8 parts by weight of tangerine peel; 4-6 parts by weight of yam; 1-3 parts by weight of Cyathula officinalis; and 1-3 parts by weight of liquorice. The Chinese medicine for treating gastric ulcers provided in the present invention can rapidly alleviate post-meal stomach pain caused by gastric ulcers, and provides remarkable benefits in treatment of gastric ulcers.

Description

위궤양 치료용 한방약제{A CHINESE MEDICINE FOR GASTRIC ULCER TREATMENT}{A CHINESE MEDICINE FOR GASTRIC ULCER TREATMENT}

본 발명은 위궤양 치료용 한방약제에 관한 것이다.The present invention relates to a herbal medicine for treating gastric ulcer.

궤양이나 소화성 궤양은 일반적인 소화성 질환 중 하나이며, 식도, 위, 십이지장, 위장-공장 문합(Gastro-jejunum Anastomosis) 근처 또는 위점막(Gastric Muscosa)을 포함하는 메켈 곁주머니(Meckel's diverticulum) 내부에 발생할 수 있다. 위궤양과 식도궤양이 매우 흔하기 때문에 일반적으로 소화성 궤양이라 함은 위궤양과 식도궤양을 의미한다. 위궤양과 식도궤양은 점막에서 위산과 펩신의 자가 소화에 의해 발생하는 것으로 알려져 있어 소화성 궤양으로 불린다. 그러나 위산과 펩신은 실제로 소화성 궤양을 발생시키는 주된 원인 중 하나일 뿐이며 다른 원인들 또한 소화성 궤양을 발생시킬 수 있다. 위궤양과 식도궤양의 병인학적, 임상적 증상은 매우 유사하여 둘 사이를 구분하는데 어려움이 있으며, 이 때문에 위 궤양들은 소화성 궤양, 위-식도 궤양으로 진단되고 있다. 만약 궤양 질환이 위에서 발생하는지 식도에서 발생하는지를 확실하게 할 수 있다면, 소화성 궤양을 직접적으로 위궤양 또는 식도궤양으로 진단할 수 있을 것이다.Ulcers or peptic ulcers are one of the common digestive diseases and can occur within the Meckel's diverticulum, including the esophagus, stomach, duodenum, gastro-jejunum anastomosis, or gastric muscle. have. Because gastric ulcers and esophageal ulcers are very common, peptic ulcers usually refer to gastric ulcers and esophageal ulcers. Stomach ulcers and esophageal ulcers are known to be caused by self-excretion of gastric acid and pepsin in the mucosa and are called peptic ulcers. However, gastric acid and pepsin are actually only one of the major causes of peptic ulcers, and other causes can also cause peptic ulcers. Stomach and clinical symptoms of gastric ulcer and esophageal ulcer are very similar and difficult to distinguish between them. So gastric ulcers are diagnosed as peptic ulcer and gastroesophageal ulcer. If ulcer disease can occur in the stomach or esophagus, a peptic ulcer can be diagnosed directly as a gastric ulcer or esophageal ulcer.

위 질환들의 주된 증상은 상복부 통증이다. 이는 상복부에서 가장 흔하고 좌상복부, 하부 흉골(after sternum) 및 검상돌기 연골(Cartilago Ensiformis)에서도 나타날 수 있다. 상복부 통증은 종종 불의의 격통, 묵직한 통증, 격렬한 통증 및 불타는 통증을 수반한다. 위궤양 통증은 종종 식후 1시간 내에 발생하며, 한-두 시간 내에 점차 완화된다. 이와 같은 하나 또는 그 이상의 주기는 다음 식사까지 발생하지 않는다. 환자 중 일부에게는 증상이 없거나, 출혈이 있거나 천공이 발생할 수 있으며, 첫 증상으로 다른 합병증이 발생하기도 한다.The main symptom of gastric diseases is epigastric pain. It is most common in the upper abdomen and may also occur in the left upper abdomen, after sternum, and Cartilago Ensiformis. Upper abdominal pain often involves a pang of pain, heavy pain, intense pain, and burning pain. Ulcer pain often occurs within one hour after meals and gradually relieves within one to two hours. One or more such cycles do not occur until the next meal. Some patients may have no symptoms, bleeding or perforation, and other complications may be the first symptom.

그러므로, 식후 복통을 완화하고 나아가 위궤양을 치료하는 한방약제의 개발이 필요하다.Therefore, it is necessary to develop a herbal medicine that alleviates postprandial abdominal pain and further treats gastric ulcer.

본 발명의 목적은 위궤양 치료용 한방약제(Chinese medicine)를 제공하는 것이다. 장기간 약제의 일반적 특성을 유지하며 식후 위통을 완화하는데 우수한 효과가 있는 위궤양 치료용 한방약제의 적합성은 향부자와 오수유를 주 성분으로 하며, 전통 약제의 효능과 현대 의약연구의 성과를 결합한다.It is an object of the present invention to provide a Chinese medicine for the treatment of gastric ulcer. The suitability of oriental herbal medicine for the treatment of stomach ulcers, which maintains the general characteristics of long-term medicines and relieves post-prandial gastric emptying, combines the efficacy of traditional medicines with the achievements of modern medicinal research.

상기 목적을 위해, 본 발명은 향부자(Cyperus rotundus) 20 내지 40 중량부, 오수유(Fructus evodiae) 10 내지 20 중량부, 황련(Coptis chinensis) 6 내지 8 중량부, 지각(Fructus aurantii) 8 내지 12 중량부, 귤피(Tangerine Peel) 4 내지 8 중량부, 참마(Yam) 4 내지 6 중량부, 천우슬(Cyathula officinalis) 1 내지 3 중량부 및 감초(Liquorice) 1 내지 3 중량부를 포함하는 위궤양 치료용 한방약제(Chinese medicine)를 제공한다.To this end, the present invention relates to a composition comprising 20 to 40 parts by weight of a cyperus rotundus, 10 to 20 parts by weight of fructus evodiae, 6 to 8 parts by weight of Coptis chinensis, 8 to 12 parts by weight of fructus aurantii 4 to 8 parts by weight of Tangerine Peel, 4 to 6 parts by weight of Yam, 1 to 3 parts by weight of Cyathula officinalis and 1 to 3 parts by weight of Liquorice. Chinese medicine is provided.

본 발명의 일 실시예에 있어서, 위궤양 치료용 한방약제는 향부자 20 중량부, 오수유 10 중량부, 황련 6 중량부, 지각 8 중량부, 귤피 4 중량부, 참마 4 중량부, 천우슬 1 중량부 및 감초 1 중량부를 포함할 수 있다.In one embodiment of the present invention, the herbal medicine for treating gastric ulcer comprises 20 parts by weight of herbal supplement, 10 parts by weight of sour milk, 6 parts by weight of Rhodiola, 8 parts by weight of crust, 4 parts by weight of citrus fruit, 4 parts by weight of yam, And 1 part by weight of licorice.

본 발명의 일 실시예에 있어서, 위궤양 치료용 한방약제는 향부자 30 중량부, 오수유 15 중량부, 황련 7 중량부, 지각 10 중량부, 귤피 6 중량부, 참마 5 중량부, 천우슬 2 중량부 및 감초 2 중량부를 포함할 수 있다.In one embodiment of the present invention, the herbal medicine for treating gastric ulcer comprises 30 parts by weight of herbal supplement, 15 parts by weight of sour milk, 7 parts by weight of persimmon, 10 parts by weight of crust, 6 parts by weight of citrus fruit, 5 parts by weight of yam, And 2 parts by weight of licorice.

본 발명의 일 실시예에 있어서, 위궤양 치료용 한방약제는 향부자 40 중량부, 오수유 20 중량부, 황련 8 중량부, 지각 12 중량부, 귤피 8 중량부, 참마 6 중량부, 천우슬 3 중량부 및 감초 3 중량부를 포함할 수 있다.In one embodiment of the present invention, the herbal medicine for treatment of gastric ulcer comprises 40 parts by weight of a herbal supplement, 20 parts by weight of sour milk, 8 parts by weight of persimmon, 12 parts by weight of crust, 8 parts by weight of citrus fruit, 6 parts by weight of yam, And 3 parts by weight of licorice.

본 발명의 일 실시예에 있어서, 위궤양 치료용 한방약제는 사유(Snake Oil) 3 내지 8 중량부를 더 포함할 수 있다.In one embodiment of the present invention, the herbal medicine for treating gastric ulcer may further comprise 3 to 8 parts by weight of Snake Oil.

상술한 한방약제의의 제조 방법과 용법은 아래와 같다:The manufacturing method and usage of the herbal medicine described above are as follows:

상술한 모든 원료들을 상기 중량부에 따라 정량하고 거즈 백(gauze bag)으로 포장한다;All of the above-mentioned raw materials are quantified according to the weight parts and packaged in a gauze bag;

상기 원료들을 포장한 상기 거즈 백을 10 내지 20배 중량부의 순수에 침지한 후 10분 동안 끓이고 30분 동안 약하게 가열하여 달인 다음, 달인 용액을 상온에서 자연 냉각한다.The gauze bag packed with the raw materials is immersed in 10 to 20 parts by weight of pure water, boiled for 10 minutes, mildly heated for 30 minutes, and naturally cooled at room temperature.

상기 달인 용액을 거른 후 얻어진 상청액이 위궤양 치료용 한방약재 생성물에 해당한다.The supernatant obtained after the above-mentioned solution is filtered corresponds to the herbal medicine therapeutic product for treating gastric ulcer.

복용 시, 환자는 한 코스로 위궤양 치료용 한방약제 70mL를 하루 3회씩 3일 동안 복용하며, 인접한 코스와의 간격은 하루이다. 3 코스를 꾸준히 복용한 후 환자가 호전될 수 있다. 코스 중 일정한 시간에 한방약제를 복용할 경우 식후 위통이 효과적으로 완화될 수 있다.When taking the drug, the patient takes 70 mL of herbal medicine for the treatment of gastric ulcer three times a day for 3 days, and the distance from the adjacent course is one day. 3 After taking the course steadily, the patient can improve. If you take herbal medicines at certain times during the course, postprandial stomach pain can be effectively relieved.

본 발명에서 제공되는 위궤양 치료용 한방약제는 위궤양에 의한 식후 위통을 빠르게 완화할 수 있으며, 위궤양 치료에 탁월한 효과가 있다.The herbal medicine for treating gastric ulcer provided in the present invention can rapidly alleviate postprandial gastric emptying caused by gastric ulcer, and has an excellent effect in the treatment of gastric ulcer.

다른 특징들과 유리한 점들은 하기 발명을 실시하기 위한 구체적인 내용에서 상세히 설명한다.Other features and advantages will be described in detail in the following detailed description of the invention.

본 발명은 적용 가능한 창의적인 여러 개념들을 제공하며, 특정 문맥에서 구체화된다. 본 발명의 실시예에서 표현되는 특정 예들은 특정 구현예를 위한 예시일 뿐이고, 본 발명을 제한하는 의미는 아니다.The present invention provides several inventive concepts that are applicable, and are embodied in a specific context. The specific examples presented in the embodiments of the present invention are only illustrative for specific embodiments and are not meant to limit the present invention.

일반성을 잃지 않고, 본 발명은 향부자(Cyperus rotundus) 20 내지 40 중량부, 오수유(Fructus evodiae) 10 내지 20 중량부, 황련(Coptis chinensis) 6 내지 8 중량부, 지각(Fructus aurantii) 8 내지 12 중량부, 귤피(Tangerine Peel) 4 내지 8 중량부, 참마(Yam) 4 내지 6 중량부, 천우슬(Cyathula officinalis) 1 내지 3 중량부 및 감초(Liquorice) 1 내지 3 중량부를 포함하는 위궤양 치료용 한방약제를 제공한다.Without loss of generality, the present invention provides a composition comprising 20-40 parts by weight of Cyperus rotundus, 10-20 parts by weight of Fructus evidiae, 6-8 parts by weight of Coptis chinensis, 8-12 parts by weight of Fructus aurantii 4 to 8 parts by weight of Tangerine Peel, 4 to 6 parts by weight of Yam, 1 to 3 parts by weight of Cyathula officinalis and 1 to 3 parts by weight of Liquorice. Medicines.

상기 모든 원료는 시중에서 가공된 제품을 구매하여 얻거나 상기 원료를 건조 및 분쇄하여 흔히 이용되는 가루를 얻는 등의 종래의 가공 방법에 의해 얻을 수 있다. 건조 방법은 가열건조 또는 자연 일광일 수 있으며, 바람직하게는 자연 일광일 수 있다. 분쇄 방법은 전통 한방 약학 분야에서 한방약제를 가루로 분쇄하는 통상적인 방법일 수 있다. 바람직하게는, 요구되는 분쇄 상태는 원료를 평균 입자 크기가 20 내지 30 메쉬(mesh), 보다 바람직하게는 20 메쉬로 하여 얻을 수 있다.All of the above raw materials can be obtained by a conventional processing method such as purchasing a product processed in the market or obtaining a commonly used powder by drying and crushing the raw material. The drying method may be heat drying or natural daylight, preferably natural daylight. The pulverization method may be a conventional method for crushing herbal medicine into flour in the field of traditional oriental medicine. Preferably, the required grinding conditions are obtained with the raw material having an average particle size of 20 to 30 mesh, more preferably 20 mesh.

본 발명에서 제공되는 위궤양 치료용 한방약제는 위궤양에 의한 식후 위통을 빠르게 완화할 수 있으며, 위궤양 치료에 탁월한 효능을 갖는다.The herbal medicine for treating gastric ulcer provided by the present invention can rapidly alleviate postprandial gastric emptying by gastric ulcer and has excellent efficacy in the treatment of gastric ulcer.

상기 기술적 방안을 더 실시하기 위해, 본 발명에서 제공되는 위궤양 치료용 한방약제의 제조 방법과 용법은 아래와 같다:In order to further carry out the above technical solutions, a method and a preparation method of a herbal medicine for treating gastric ulcer provided in the present invention are as follows:

상술한 모든 원료들을 상기 중량부에 따라 정량하고 거즈 백(gauze bag)으로 포장한다;All of the above-mentioned raw materials are quantified according to the weight parts and packaged in a gauze bag;

상기 원료들을 포장한 상기 거즈 백을 10 내지 20배 중량부의 순수에 침지한 후 10분 동안 끓이고 30분 동안 약하게 가열하여 달인 다음, 달인 용액을 상온에서 자연 냉각한다.The gauze bag packed with the raw materials is immersed in 10 to 20 parts by weight of pure water, boiled for 10 minutes, mildly heated for 30 minutes, and naturally cooled at room temperature.

상기 달인 용액을 거른 후 얻어진 상청액이 위궤양 치료용 한방약재 생성물에 해당한다.The supernatant obtained after the above-mentioned solution is filtered corresponds to the herbal medicine therapeutic product for treating gastric ulcer.

복용 시, 환자는 한 코스로 위궤양 치료용 한방약제 70mL를 하루 3회씩 3일 동안 복용하며, 인접한 코스와의 간격은 하루이다. 3 코스를 꾸준히 복용한 후 환자가 호전될 수 있다. 코스 중 일정한 시간에 한방약제를 복용할 경우 식후 위통이 효과적으로 완화될 수 있다.When taking the drug, the patient takes 70 mL of herbal medicine for the treatment of gastric ulcer three times a day for 3 days, and the distance from the adjacent course is one day. 3 After taking the course steadily, the patient can improve. If you take herbal medicines at certain times during the course, postprandial stomach pain can be effectively relieved.

아래 실시예들에서 본 발명을 보다 상세히 설명한다.The present invention will be described in more detail in the following examples.

실시예 1 내지 5Examples 1 to 5

실시예 1 내지 5는 본 발명에서 제공되는 위궤양 치료용 한방약제를 설명하기 위한 것이다.Examples 1 to 5 are for illustrating herbal medicine for treating gastric ulcer provided in the present invention.

실시예 1 내지 5의 위궤양 치료용 한방약제는 표 1에 나타난 배분 방법에 따라 얻어진다.The herbal medicine for the treatment of gastric ulcer of Examples 1 to 5 is obtained according to the distribution method shown in Table 1.

실시예Example 향부자
(g)
Herbalist
(g)
오수유
(g)
Sour milk
(g)
황련
(g)
goldthread
(g)
지각
(g)
tardy
(g)
귤피
(g)
Citrus
(g)
참마
(g)
yam
(g)
천우슬
(g)
Cloth
(g)
감초
(g)
licorice
(g)
사유
(g)
Reason
(g)
실시예 1Example 1 2020 1010 66 88 44 44 1One 1One 00 실시예 2Example 2 3030 1515 77 1010 66 55 22 22 00 실시예 3Example 3 4040 2020 88 1212 88 66 33 33 00 실시예 4Example 4 3030 1515 77 1010 66 55 22 22 33 실시예 5Example 5 4040 2020 88 1212 88 66 33 33 88

실험예 1 내지 3은 본 발명에서 제공되는 위궤양 치료용 한방약제의 치료 효과를 설명하기 위한 것이다.Experimental Examples 1 to 3 are for explaining the therapeutic effect of the herbal medicine for treating gastric ulcer provided in the present invention.

실험예Experimental Example (1) 선천적 원인으로 인한 위궤양의 개선 (1) improvement of gastric ulcer due to congenital cause

선천적 원인으로 인한 위궤양을 겪고 있는 150명의 남녀 환자를 30 내지 55세 범위에서 선택하고 5개 그룹으로 나누었다(그룹 당 30명씩). 5개 그룹의 환자들은 한 코스로 위궤양 치료용 한방약제 70mL를 하루 3회씩 3일 동안 복용하였으며, 인접한 코스와의 간격은 하루였다. 3 코스를 꾸준히 복용한 후 복용 전과 비교하여 효과를 관찰하였으며, 어떠한 증상도 없는 경우(증상이 없어진 경우) O로 표시하였다. 증상이 눈에 띄게 완화된 경우는 △로 표시하였다. 증상의 개선이 거의 없는 경우는 X로 표시하였으며, 치료 효과를 표 2에 나타내었다.150 male and female patients suffering from gastric ulcers due to congenital causes were selected from 30 to 55 years old and divided into 5 groups (30 per group). Patients in five groups took 70 mL of Oriental medicine for gastric ulcer treatment three times a day for 3 days, and the distance from the adjacent course was one day. The effect of 3 courses was observed compared with before taking, and when there was no symptom (symptom disappearance), O was marked. When the symptom was remarkably alleviated, it was indicated as?. The symptom improvement was scarcely indicated by X, and the treatment effect was shown in Table 2.

그룹group 효과effect OO XX 1One 2222 44 44 22 2323 55 22 33 2525 33 22 44 2727 22 1One 55 2626 22 22

실험예Experimental Example (2) 생활적 요인에 의한 위궤양의 개선 (2) Improvement of gastric ulcer due to living factors

생활적 요인으로 인한 위궤양을 겪고 있는 150명의 남녀 환자를 30 내지 55세 범위에서 선택하고 5개 그룹으로 나누었다(그룹 당 30명씩). 5개 그룹의 환자들은 한 코스로 위궤양 치료용 한방약제 70mL를 하루 3회씩 3일 동안 복용하였으며, 인접한 코스와의 간격은 하루였다. 3 코스를 꾸준히 복용한 후 복용 전과 비교하여 효과를 관찰하였으며, 어떠한 증상도 없는 경우(증상이 없어진 경우) O로 표시하였다. 증상이 눈에 띄게 완화된 경우는 △로 표시하였다. 증상의 개선이 거의 없는 경우는 X로 표시하였으며, 치료 효과를 표 3에 나타내었다.150 men and women suffering from gastric ulcers due to life-threatening factors were selected from 30 to 55 years old and divided into 5 groups (30 per group). Patients in five groups took 70 mL of Oriental medicine for gastric ulcer treatment three times a day for 3 days, and the distance from the adjacent course was one day. The effect of 3 courses was observed compared with before taking, and when there was no symptom (symptom disappearance), O was marked. When the symptom was remarkably alleviated, it was indicated as?. The symptom improvement was scarcely indicated as X, and the treatment effect was shown in Table 3.

그룹group 효과effect OO XX 1One 1818 99 33 22 2020 88 22 33 2323 44 33 44 2525 44 1One 55 2222 77 1One

실험예Experimental Example (3) 감염성 인자에 의한 위궤양의 개선 (3) Improvement of gastric ulcer by infectious factor

감염성 인자에 인한 위궤양을 겪고 있는 150명의 남녀 환자를 30 내지 55세 범위에서 선택하고 5개 그룹으로 나누었다(그룹 당 30명씩). 5개 그룹의 환자들은 한 코스로 위궤양 치료용 한방약제 70mL를 하루 3회씩 3일 동안 복용하였으며, 인접한 코스와의 간격은 하루였다. 3 코스를 꾸준히 복용한 후 복용 전과 비교하여 효과를 관찰하였으며, 어떠한 증상도 없는 경우(증상이 없어진 경우) O로 표시하였다. 증상이 눈에 띄게 완화된 경우는 △로 표시하였다. 증상의 개선이 거의 없는 경우는 X로 표시하였으며, 치료 효과를 표 4에 나타내었다.150 male and female patients with gastric ulcers due to infectious agents were selected from the age range of 30 to 55 years and divided into 5 groups (30 per group). Patients in five groups took 70 mL of Oriental medicine for gastric ulcer treatment three times a day for 3 days, and the distance from the adjacent course was one day. The effect of 3 courses was observed compared with before taking, and when there was no symptom (symptom disappearance), O was marked. When the symptom was remarkably alleviated, it was indicated as?. The symptom improvement was scarcely indicated by X, and the treatment effect was shown in Table 4.

그룹group 효과effect OO XX 1One 1717 1010 33 22 1919 99 22 33 2020 66 44 44 2525 44 1One 55 2727 22 1One

상기 실험예들의 시험 결과로부터 본 발명에서 제공되는 위궤양 치료용 한방약제가 식후 위통을 완화하고 위궤양을 치료하는 데 탁월한 효능을 갖는 것을 알 수 있었다.From the test results of the above Experimental Examples, it was found that the herbal remedy herbal medicine provided in the present invention has excellent efficacy in relieving postprandial gastric pain and treating gastric ulcer.

Claims (5)

향부자(Cyperus rotundus) 20 내지 40 중량부, 오수유(Fructus evodiae) 10 내지 20 중량부, 황련(Coptis chinensis) 6 내지 8 중량부, 지각(Fructus aurantii) 8 내지 12 중량부, 귤피(Tangerine Peel) 4 내지 8 중량부, 참마(Yam) 4 내지 6 중량부, 천우슬(Cyathula officinalis) 1 내지 3 중량부 및 감초(Liquorice) 1 내지 3 중량부를 포함하는 위궤양 치료용 한방약제.
20 to 40 parts by weight of Cyperus rotundus, 10 to 20 parts by weight of Fructus evodiae, 6 to 8 parts by weight of Coptis chinensis, 8 to 12 parts by weight of Fructus aurantii, Tangerine Peel 4 To 8 parts by weight, Yam (Yam) 4 to 6 parts by weight, Cyathula officinalis 1 to 3 parts by weight and Liquorice 1 to 3 parts by weight.
청구항 1에 있어서, 향부자 20 중량부, 오수유 10 중량부, 황련 6 중량부, 지각 8 중량부, 귤피 4 중량부, 참마 4 중량부, 천우슬 1 중량부 및 감초 1 중량부를 포함하는 위궤양 치료용 한방약제.
The composition for treating gastric ulcer according to claim 1, which comprises 20 parts by weight of herbal supplement, 10 parts by weight of sour milk, 6 parts by weight of Rhodiola, 8 parts by weight of crust, 4 parts by weight of citrus fruit, 4 parts by weight of yam, 1 part by weight of licorice, Oriental medicine.
청구항 1에 있어서, 향부자 30 중량부, 오수유 15 중량부, 황련 7 중량부, 지각 10 중량부, 귤피 6 중량부, 참마 5 중량부, 천우슬 2 중량부 및 감초 2 중량부를 포함하는 위궤양 치료용 한방약제.
A method for treating gastric ulcer, comprising the steps of: applying 30 parts by weight of herbal supplement, 15 parts by weight of sour milk, 7 parts by weight of Rhodiola, 10 parts by weight of crust, 6 parts by weight of citrus fruit, 5 parts by weight of yam, Oriental medicine.
청구항 1에 있어서, 향부자 40 중량부, 오수유 20 중량부, 황련 8 중량부, 지각 12 중량부, 귤피 8 중량부, 참마 6 중량부, 천우슬 3 중량부 및 감초 3 중량부를 포함하는 위궤양 치료용 한방약제.
A method for treating gastric ulcer comprising the steps of: (1) preparing a composition comprising 40 parts by weight of a perfume, 20 parts by weight of sour oil, 8 parts by weight of Rhodiola, 12 parts by weight of crust, 8 parts by weight of citrus fruit, 6 parts by weight of yam, Oriental medicine.
청구항 1 내지 4 중 어느 한 항에 있어서, 사유(Snake Oil) 3 내지 8 중량부를 더 포함하는 위궤양 치료용 한방약제.
The herbal medicine for treating gastric ulcer according to any one of claims 1 to 4, further comprising 3 to 8 parts by weight of Snake Oil.
KR1020170161964A 2017-11-29 2017-11-29 A chinese medicine for gastric ulcer treatment KR20190063115A (en)

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