CN116270748A - A Chinese medicinal composition for treating esophageal ulcer and esophageal cancer, and its preparation method - Google Patents

Abstract

The invention provides a traditional Chinese medicine composition for treating esophageal ulcers and esophageal cancers and a preparation method thereof, wherein the effective components of the traditional Chinese medicine composition comprise centipedes and pearls, and the ratio of the raw material medicines of the effective components is as follows: 2.0-5.0 parts of centipede and 0.5-1.5 parts of pearl; the parts are mass parts. The treatment principle of the invention is that the invention has the functions of counteracting toxic substances, expelling toxin, softening hardness, dissipating stagnation, promoting granulation and removing tumor; wherein, the centipede has the functions of dispelling wind, relieving spasm, dredging channels and collaterals, relieving pain, eliminating toxin, resolving masses and removing lumps; pearl has effects of nourishing yin, calming endogenous wind, clearing heat, removing toxic substance, promoting granulation, and removing toxic substance. The invention has precise and appropriate compatibility, can rapidly improve the related symptoms of patients with esophageal ulcer and esophageal cancer, such as eating difficulty, can heal after continuously taking a plurality of treatment courses, and has no adverse reaction.

Description

A Chinese medicinal composition for treating esophageal ulcer and esophageal cancer, and its preparation method

Technical Field

The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine composition for treating esophageal ulcers and esophageal cancers and a preparation method thereof.

Background

Esophageal ulcers are clinically common gastric disorders, often occurring in patients with reflux esophagitis and sliding hiatal hernias with esophageal reflux. Ulcers may occur on squamous or columnar epithelium, as well as after esophageal-gastric anastomosis or esophageal-jejunostomy.

Esophageal cancer, also known as esophageal cancer, is a malignancy that occurs in the epithelium of the esophagus, accounting for 2% of all malignant tumors, and about 30 tens of thousands die annually worldwide. The Chinese is a country with high esophageal cancer incidence in the world, and is one of countries with high esophageal cancer mortality in the world, and the average annual mortality rate is 1.3-90.9/10 ten thousand.

At present, the treatment of esophageal ulcer mainly adopts western medicine treatment, has quick curative effect but is easy to relapse, and usually has side effects. The treatment for esophagus cancer mainly comprises operation treatment, radiation treatment, chemotherapy and the like. Among them, surgical treatment is still the first method for treating esophageal cancer, but some complications generated after esophageal cancer surgery often cause malnutrition, anemia and hypoproteinemia, and affect the survival quality of patients. In addition, because early esophageal cancer is difficult to find, patients often have middle and late stages in their treatment, and often lose the opportunity of surgical treatment. Radiotherapy and chemotherapy have the same problems of great side effects and reduced life quality of patients.

Therefore, in order to alleviate the suffering of the disease of the patient, a safe and effective medicament is needed for treating esophageal ulcers and cancers.

Disclosure of Invention

Aiming at the problems existing in the prior art, the invention aims to provide a traditional Chinese medicine composition for treating esophageal ulcers and esophageal cancers and a preparation method thereof, wherein the traditional Chinese medicine composition can rapidly improve relevant symptoms of patients with esophageal ulcers and esophageal cancers, including eating difficulties, and can heal after continuously taking a plurality of treatment courses of symptoms.

The invention aims at realizing the following technical scheme:

according to modern Chinese medicine theory and combined with clinical treatment experience, the first aspect of the invention provides a traditional Chinese medicine composition for treating esophageal ulcers and esophageal cancers, wherein the effective components of the traditional Chinese medicine composition comprise centipedes and pearls, and the ratio of the raw materials of the effective components is as follows:

2.0-5.0 parts of centipede

0.5-1.5 parts of pearl;

the parts are mass parts.

Further, the effective component of the centipede is powder obtained by baking the centipede with slow fire and grinding the centipede.

Further, the active ingredients of the pearl are powder obtained by cleaning, airing and grinding the pearl.

The second aspect of the invention provides a preparation method of a traditional Chinese medicine composition for treating esophageal ulcers and esophageal cancers, which comprises the following steps:

selecting a plurality of centipedes with big size, long length, red head, reddish brown feet, black green body and complete head and feet, cleaning, airing, baking with slow fire, and grinding into centipede powder;

selecting a plurality of pearls, cleaning, packaging with gauze, boiling with bean curd for 1-3 hours, taking out the pearls, cleaning, airing and grinding into pearl powder;

the centipede powder and the pearl powder are respectively weighed according to the proportion of the raw materials, and are uniformly mixed to obtain the traditional Chinese medicine composition for treating the esophageal ulcer and the esophageal cancer.

Compared with the prior art, the invention has the beneficial effects that:

1. aiming at the pathogenesis of esophageal ulcer and esophageal cancer, the treatment principle of the traditional Chinese medicine composition is to attack toxin, expel toxin, soften hardness, dissipate stagnation, promote tissue regeneration and remove tumor; wherein, the centipede has the functions of dispelling wind, relieving spasm, dredging channels and collaterals, relieving pain, eliminating toxin, resolving masses and removing lumps; pearl has effects of nourishing yin, calming endogenous wind, clearing heat, removing toxic substance, promoting granulation, and removing toxic substance. The invention has precise and appropriate compatibility, can rapidly improve the related symptoms of patients with esophageal ulcer and esophageal cancer, including eating difficulty, and can heal after continuously taking a plurality of treatment courses.

2. The traditional Chinese medicine composition is powder, is orally taken twice a day, and is orally taken after being mixed with water; twenty days is a treatment course, and the medicine does not hurt qi, blood and viscera and has no adverse reaction after long-term administration.

Drawings

The invention is further illustrated by the following examples in conjunction with the accompanying drawings:

FIG. 1 is a diagram showing the results of gastroscopy report before taking medicine in case 1 in the example;

FIGS. 2 and 3 are graphs showing the results of two gastroscopies after taking the medicine in case 1 according to the examples;

FIG. 4 is a diagram showing the results of gastroscopy before taking medicine in case 2 in the example;

fig. 5 is a diagram showing the results of gastroscopy after taking medicine in case 2 described in the example.

Detailed Description

Example 1

The embodiment provides a traditional Chinese medicine composition for treating esophageal ulcers and esophageal cancers, wherein the effective components of the traditional Chinese medicine composition comprise centipedes and pearls, and the ratio of the raw materials of the effective components is as follows: scolopendra (two pieces removed from the head) 3.0g, margarita 1.0g. The preparation method of the traditional Chinese medicine composition comprises the following steps:

selecting a plurality of centipedes with big size, long length, red head, reddish brown feet, black green body and complete head and feet, cleaning, airing, baking with slow fire, and grinding into centipede powder.

Selecting multiple pearls, cleaning, wrapping with gauze, decocting with bean curd for 2 hr, taking out pearls, cleaning, air drying, and grinding into pearl powder. The pearl effect can be effectively improved after the pearl is boiled together with the bean curd.

According to the proportion of the raw materials, 3.0g of centipede powder and 1.0g of pearl powder are respectively weighed and evenly mixed to obtain the traditional Chinese medicine composition for treating esophageal ulcer and esophageal cancer.

The treatment method comprises the following steps: the medicine is taken orally twice a day after being mixed with water; generally 21 days is a treatment course (after a treatment course, stopping the medicine for 4-5 days). Patients with esophageal ulcer take 1-2 courses of treatment, and patients with esophageal cancer take 2-5 courses of treatment.

The contraindications of taking the traditional Chinese medicine composition include: spicy (wine), fishy, egg, and fowl meat.

Example 2

The embodiment provides a traditional Chinese medicine composition for treating esophageal ulcers and esophageal cancers, which comprises centipedes and pearls in the following proportions: 2.0g of centipede and 1.5g of pearl.

The preparation method, administration contraindications and the like are the same as those of example 1.

Example 3

The embodiment provides a traditional Chinese medicine composition for treating esophageal ulcers and esophageal cancers, which comprises centipedes and pearls in the following proportions: 5.0g of centipede and 0.5g of pearl.

The preparation method, administration contraindications and the like are the same as those of example 1.

Clinical cases and efficacy analysis:

case 1:

yellow to a certain age, female, 54 years old. For half a year of dysphagia, gastroscopy was performed in 1/5/2006 to the tumor hospital in Paeonia suffruticosa, and pathological examination was performed as shown in FIG. 1, to confirm esophageal cancer (three tumors in lower esophageal segment) and esophageal ulcer. The patient did not take any treatment, and the traditional Chinese medicine composition (taken with water and twice a day) described in the example 1 was taken after 26 months in 2006, and the disease symptoms were greatly improved and the feeding was changed to normal for more than ten days. The patient continuously takes medicine for one treatment course, the subjective state of illness is improved, and the patient goes to the peony river city tumor hospital again for gastroscopy on 3 months and 2 days in 2006, and as shown in figure 2, three tumors disappear two, one is not obvious, and the esophageal ulcer is healed. Continuing the second course of medication, the patient had a disease cured from 14 days 4 months 2006 to the peony river tumor hospital for gastroscopy as shown in figure 3. The patient had healed 17 years since 2006.

Case 2:

liu is somewhere, woman is 63 years old, self-feel heart and mouth pain, heartburn, acid regurgitation and choking during eating. Gastroscopy was performed at the people hospitals in the city of dongning at 3 and 4 of 2022, and as shown in fig. 4, reflux esophagitis, esophageal ulcer erosion and chronic atrophic gastritis were diagnosed. After diagnosis, the patients are treated for a long time, and the disease condition is not improved. The patient started taking the traditional Chinese medicine composition described in example 2 for treatment (water-adjusted oral administration twice a day) at the month of 2022, and after oral treatment for one course of treatment, gastroscopy was performed at the second people hospital from the city of Paeonia suffruticosa at the month of 2022 at the month of 12 at the month of 29, as shown in fig. 5, the esophageal ulcer healed and all symptoms were substantially disappeared.

Case 3:

wang Mou after men, 76 years old, dysphagia is caused by gastroscopy from 11/8/2008 to forestry hospital in Paeonia river, and esophageal cancer is confirmed. After diagnosis, radiotherapy treatment and chemotherapy are not performed. The treatment of the traditional Chinese medicine composition described in example 3 was taken orally (water-adjusted oral administration twice a day) from 12 months and 22 days 2008. After two weeks of treatment the condition was significantly improved and eating was essentially normal.

After four courses of oral treatment and normal diet, the patient goes to the forestry hospital in the city of Paeonia suffruticosa again to carry out gastroscopy, and the esophagus cancer is healed.

Finally, it should be noted that the above only illustrates the technical solution of the present invention and is not limiting, and although the present invention has been described in detail with reference to the preferred arrangement, it should be understood by those skilled in the art that modifications and equivalents may be made to the technical solution of the present invention without departing from the spirit and scope of the technical solution of the present invention.

Claims (7)

1. The Chinese medicinal composition for treating esophageal ulcer and esophageal cancer is characterized in that the Chinese medicinal composition comprises the following active ingredients of centipede and pearl:

2.0-5.0 parts of centipede

0.5-1.5 parts of pearl;

the parts are mass parts.

2. The traditional Chinese medicine composition for treating esophageal ulcers and cancers according to claim 1, wherein the ratio of the active ingredients is as follows:

scolopendra 3.0 parts

1.0 part of pearl.

3. The traditional Chinese medicine composition for treating esophageal ulcers and cancers according to claim 1, wherein the ratio of the active ingredients is as follows:

centipede 2.0 parts

1.5 parts of pearl.

4. The traditional Chinese medicine composition for treating esophageal ulcers and cancers according to claim 1, wherein the ratio of the active ingredients is as follows:

5.0 parts of centipede

0.5 part of pearl.

5. The Chinese medicinal composition for treating esophageal ulcers and cancers according to any one of claims 1-4, wherein the effective component of centipede is powder obtained by baking and grinding the centipede with slow fire.

6. The Chinese medicinal composition for treating esophageal ulcers and cancers as claimed in any one of claims 1-4, wherein the active ingredients of the pearl are powders obtained by washing, air drying and grinding the pearl.

7. A method for preparing the traditional Chinese medicine composition for treating esophageal ulcers and cancers according to any one of claims 1-6, which is characterized by comprising the following steps:

selecting a plurality of centipedes with big size, long length, red head, reddish brown feet, black green body and complete head and feet, cleaning, airing, baking with slow fire, and grinding into centipede powder;

selecting a plurality of pearls, cleaning, packaging with gauze, boiling with bean curd for 1-3 hours, taking out the pearls, cleaning, airing and grinding into pearl powder;

the Chinese medicinal composition for treating esophageal ulcer and esophageal cancer is prepared by respectively weighing Scolopendra powder and Margarita powder according to the ratio of the raw materials of any one of claims 1-4, and mixing.

Images