KR20190020950A - Low irritating cosmetic composition for skin whitening comprising albutin - Google Patents

Abstract

The present invention relates to a skin whitening cosmetic composition comprising arbutin, niacinamide, an Aloe barbadensis leaf extract, a Malpighia emarginata fruit extract, a Camellia sinensis leaf extract, a Brassica oleracea extract, Simmondsia chinensis seed oil and an amino acid complex as active ingredients. The skin whitening cosmetic composition for according to the present invention exhibits a skin soothing effect that alleviates skin irritation which may be caused when arbutin and niacinamide are used, and has an excellent skin whitening effect.

Description

[0001] The present invention relates to a hypoallergic cosmetic composition for skin whitening comprising albutin,

The present invention relates to a hypoallergenic skin whitening cosmetic composition comprising arbutin, niacinamide and a skin soothing component as an active ingredient.

The skin color of a person is determined by the concentration and distribution of melanin in the skin. In addition to hereditary factors, it is also affected by environmental or physiological conditions such as sunlight, fatigue, and stress. Melanin is synthesized in melanocytes in the epidermis of the skin. In the melanosome of melanocytes, an enzyme called tyrosinase acts on tyrosine, a type of amino acid, resulting in dopa (DOPA), dopaquinone ), And then it is made through a non-enzymatic oxidation reaction. When such a synthesis of melanin occurs excessively in the skin, it darkens skin tone, and causes spots and freckles. Thus, inhibiting the activity of tyrosinase in the skin to inhibit the synthesis of melanin pigment not only makes it possible to whiten the skin tone to brighten the skin tone, but also to reduce skin irritation caused by ultraviolet rays, hormones and hereditary causes, It can improve constipation.

A variety of extracts including hydroquinone, ascorbic acid, kojic acid, glutathione, arbutin, and bark extract have been used as substances capable of inhibiting the activity of tyrosinase. However, they have problems in safety of skin and stability of cosmetic formulation, In the case of arbutin, side effects that cause skin irritation occur.

Under these circumstances, the inventors of the present invention have continued to develop a substance having a whitening effect and a less adverse side effect such as skin irritation. As a result, it has been found that it contains arbutin, niacinamide, aloe vera leaf extract, acerola extract, green tea extract and broccoli extract And the skin irritation is alleviated while exhibiting an excellent whitening effect of the cosmetic composition. Thus, the present invention has been completed.

Korean Patent No. 10-0923141 Korean Patent Publication No. 10-2010-0069759

Accordingly, an object of the present invention is to provide an extract of albutin, niacinamide, Aloe barbadensis leaf, Malpighia emarginata fruit, Camellia sinensis leaf, Extract and broccoli (Brassica oleracea var. Italica) extract as an active ingredient.

In order to accomplish the object of the present invention, the present invention provides a method for producing an extract of albutin, niacinamide, Aloe barbadensis leaf, Malpighia emarginata fruit, Camellia sinensis leaf, Extract and broccoli (Brassica oleracea var. Italica) extract as an active ingredient.

Also, the present invention provides a cosmetic composition for skin whitening comprising the cosmetic composition for skin whitening, further comprising a cosmetic composition comprising a cosmetic composition comprising a cosmetic composition comprising:

The cosmetic composition for skin whitening comprising arbutin, niacinamide, aloe vera leaf extract, acerola extract, green tea extract, broccoli extract, jojoba seed oil and amino acid complex of the present invention as an active ingredient can be used for skin Has a skin soothing effect to alleviate irritation, has an excellent skin whitening effect, and can be effectively used as a whitening cosmetic composition.

The present inventors have found that the extracts of albutin, niacinamide, Aloe barbadensis leaf, Malpighia emarginata fruit, Camellia sinensis leaf, Broccoli (Brassica oleracea var. Italica) The present invention has been accomplished by discovering that a cosmetic composition containing Simmondsia chinensis seed oil and an amino acid complex exhibits whitening effect as well as skin soothing effect.

Particularly, in the present invention, when a cosmetic composition prepared by mixing arbutin, niacinamide, aloe vera leaf extract, acerola extract, green tea extract and broccoli extract is used, the whitening effect is remarkably improved as compared with a composition containing a part of these components. (See Experimental Example 1).

Accordingly, the present invention relates to a composition comprising albutin, niacinamide, Aloe barbadensis leaf extract, Malpighia emarginata fruit extract, Camellia sinensis leaf extract and Broccoli (Brassica oleracea var. Italica) The present invention provides a cosmetic composition for skin whitening comprising an extract as an active ingredient.

The albutin of the present invention is a substance which is contained in a large amount in a mushroom and is effective for whitening. It is a chemical structure similar to hydroquinone, which is a melanin production inhibiting ingredient, and has antioxidant, skin conditioning agent, whitening improving effect And is widely used worldwide due to the stability of the formulation.

The niacinamide of the present invention is a kind of niacin, a vitamin B group, and niacinamide is a water-soluble vitamin B3, also known as nicotinamide. It has the effect of simultaneously promoting the synthesis of cholesterol and fatty acid necessary for formation of lamellar structure together with ceramides, thereby reducing moisture loss of the epidermis and improving the fat mass, and is used for obtaining a whitening effect in the field of cosmetics.

The aloe barbadensis leaf (Aloe Vera) of the present invention is originated from the Mediterranean region and Africa and contains vitamin A, C, D, E, B12, fatty acid, amino acid, selenium, calcium and aloin, And aloesin. It contains about 300 various components. The gel-like liquid contained in the leaves is known to have an effect of treating burns and arthritis. It is used for various purposes such as raw materials for cosmetics and pharmaceuticals, and for food. It neutralizes toxins caused by sterilization, fatigue and skin neutralization, And ulcers.

The above-mentioned acerola (Malpighia emarginata fruit (Acerola)) is a fruit produced in a shrub of a Malphigia family native to Brazil, and contains vitamins, minerals and the like, and is particularly rich in vitamin C. In addition, it is known that antioxidants such as anthocyanin and polyphenol are abundant, so that they have excellent aging suppressing effect, and have a skin cleansing effect, a moisturizing effect and a converging action.

The green tea (Camellia sinensis leaf) of the present invention is prepared by inactivating an oxidizing enzyme present in the leaves of a camellia sinensis using fire or steam using shoots or leaves of Camellia sinensis belonging to Camellia sinensis , Has been consumed as a symbol of tea since BC. As the pharmacological mechanism of the various ingredients in green tea is becoming more and more known, its value is recognized by the general public as well. Antioxidants, antiinflammation, antimutagenesis, prevention of heart disease, antiangiogenesis, apoptosis, Cholesterol lowering, atherosclerosis, anti-diabetic, antimicrobial, antiviral, and anti-aging.

The broccoli (Brassica oleracea var. Italica (Broccoli)) of the present invention is a plant belonging to the group of crucifers and contains a large amount of beta-carotene, rutin, ascorbic acid, selenium, quercetin, glutathione, Vitamin C, and folic acid. Broccoli is effective in increasing collagen synthesis in the skin, preventing aging of the skin, enhancing skin resistance from harmful substances, imparting tension to the skin, and helping the pore convergence.

The aloe vera leaf extract, acerola extract, green tea extract and broccoli extract according to the present invention can be obtained by extracting and extracting the extract using methods known in the art for extracting and isolating the extract, Can be extracted from the aloe vera leaves, acerola, green tea or broccoli using an appropriate solvent. Any suitable solvent that can be used to obtain the extract may be any of those accepted in the art, and water or an organic solvent may be used. Examples of the solvent include alcohols having 1 to 4 carbon atoms, acetone, ether, and the like, including purified water, methanol, ethanol, propanol, isopropanol, butanol, Various solvents such as benzene, chloroform, ethyl acetate, methylene chloride, hexane and cyclohexane may be used alone or in combination. But is not limited to.

As the extraction method, any one of the methods such as hot water extraction method, cold extraction method, reflux cooling extraction method, solvent extraction method, steam distillation method, ultrasonic extraction method, elution method and compression method can be selected and used. In addition, the desired extract may be further subjected to a conventional fractionation process or may be purified using a conventional purification method. There is no limitation on the method for producing the extract of the present invention, and any known method can be used.

For example, the aloe vera leaf, acerola, green tea and broccoli extracts contained in the composition of the present invention are subjected to centrifugation, filtration, concentration, freeze-drying, and stored in a refrigerated room And the primary extract may be prepared into a powder state by an additional process such as vacuum distillation and freeze-drying or spray-drying. In addition, the primary extract can be further fractionated using a variety of chromatographies, such as silica gel column chromatography, thin layer chromatography, high performance liquid chromatography, .

Therefore, in the present invention, the aloe vera leaf, acerola, green tea or broccoli extract is a concept including all the extracts, fractions and tablets obtained in each step of extraction, fractionation or purification, their diluted solutions, concentrates or dried products.

The cosmetic composition for skin whitening according to the present invention comprises 4.0 to 6.0 parts by weight of arbutin, 1.0 to 3.0 parts by weight of niacinamide, 0.05 to 0.15 part by weight of aloe vera leaf extract, 0.05 to 0.15 part by weight of acerola extract, 0.05 to 0.15 part by weight of green tea leaf extract and 0.05 to 0.15 part by weight of broccoli extract.

In addition, the cosmetic composition for skin whitening according to the present invention may further comprise a combination of jojoba seed oil (Simmondsia chinensis seed oil) and an amino acid complex.

The Jojoba seed oil (Simmondsia chinensis (jojoba) seed oil) of the present invention is an oil obtained by joining the seeds of jojoba by cold pressing, and its chemical structure is similar to skin sebum and penetrates well to the skin. It is known that it is effective for sensitive skin because it has excellent anti-skin effect on skin tissue regeneration by regulating sebum without blocking, anti-inflammatory function with good moisturizing effect and antioxidant effect without skin irritation.

The amino acid complex of the present invention is a complex of an amino acid that is the same as or similar to the amino acid composition in the stratum corneum of the skin. The amino acid complex plays an important role in maintaining moisturization by supplying nutrition to skin cells and activating skin fibroblasts .

The amino acid complexes according to the present invention may be used in combination with lysine, histidine, arginine, aspartic acid, threonine, serine, gluamic acid, proline, Selected from the group consisting of glycine, alanine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine and cysteine. Or more than two amino acids. Preferably, the above-mentioned 17 kinds of amino acids may be mixed by the same weight to prepare an amino acid complex.

The cosmetic composition for skin whitening according to the present invention may comprise 0.5 to 1.5 parts by weight of jojoba seed oil and 0.07 to 0.27 parts by weight of amino acid complex based on 100 parts by weight of the total cosmetic composition.

The amino acid conjugate according to the present invention may contain 0.005 to 0.015 part by weight of lysine, 0.005 to 0.015 part by weight of histidine, 0.005 to 0.015 part by weight of arginine, 0.005 to 0.015 part by weight of aspartic acid, 0.005 to 0.015 part by weight of glutamic acid, 0.005 to 0.015 part by weight of glutamic acid, 0.005 to 0.015 part by weight of proline, 0.005 to 0.015 part by weight of glycine, 0.005 to 0.015 part by weight of alanine, 0.005 to 0.015 part by weight of valine, 0.005 to 0.015 part by weight of isoleucine, 0.005 to 0.015 part by weight of leucine, 0.005 to 0.015 part by weight of tyrosine, 0.005 to 0.015 part by weight of phenylalanine and 0.005 to 0.015 part by weight of cysteine.

In the present invention, it was confirmed that the cosmetic composition comprising a combination of arbutin, niacinamide, aloe vera leaf extract, acerola extract, green tea extract and broccoli extract together with jojoba seed oil and amino acid complex was excellent in whitening effect, and arbutin and niacin (Experimental Example 1 and Experimental Example 2), and the skin soothing effect according to the content of each ingredient was compared to determine the optimal content range (See Experimental Example 3).

The cosmetic composition for skin whitening according to the present invention comprises 4.0 to 6.0 parts by weight of arbutin, 1.0 to 3.0 parts by weight of niacinamide, 0.08 to 0.12 parts by weight of aloe vera leaf extract, 0.08 to 0.12 parts by weight of acerola extract, 0.08 to 0.12 parts by weight of green tea leaf extract, 0.08 to 0.12 parts by weight of broccoli extract, 0.8 to 1.2 parts by weight of jojoba seed oil and 0.12 to 0.22 parts by weight of amino acid complex.

The cosmetic composition for skin whitening according to the present invention can be used as a skin whitening cosmetic composition according to the present invention as a cream whitening cream for skin whitening, It may be one or more formulations selected from the group consisting of essence, foundation, makeup base, pack, patch, gel, powder, soap, cleansing foam, cleansing lotion, cleansing cream, body lotion or body cleanser.

In the cosmetic composition of the present invention, components other than the above-mentioned essential components in the external preparation for each formulation can be appropriately selected and mixed by those skilled in the art according to the formulation or purpose of use of the external preparation.

In addition, the cosmetic composition of the present invention may further comprise a skin protecting agent which can provide skin care, such as a skin moisturizing agent, a skin softening agent, a moisture blocking agent, A preservative, a vitamin, a blocking agent, an antioxidant, an antioxidant, a preservative, a preservative, an antioxidant, an antioxidant, a preservative, a stabilizer, a pH adjuster, a foaming agent, Such as wetting agents, essential oils, fragrances, dyes, pigments, hydrophilic or lipophilic active agents, lipid vesicles or any other ingredients commonly used in cosmetics. These adjuvants are introduced in amounts commonly used in the cosmetics field.

Examples of the skin protection agent include extracts derived from bark extract, Indian oriental resin extract, squalane, hydrolyzed collagen, allantoin, caprylic hydroxamic acid, hyaluronic acid, rosemary extract, gossam extract, tocopheryl acetate, D- Can be used.

As the wetting agent, glycerin, butylene glycol, sodium hyaluronate, serine, sorbitol, mannitol, propylene glycol, ethylene glycol, cholesterol, cholesterol ester and the like can be used.

As the emulsifier, glyceryl stearate, phage-40 stearate, sorbitan sesquioleate, polysorbate 60, glycystearate / phage-100 stearate, pro-type glyceryl stearate and the like can be used.

Examples of softening agents include caprylic / capric triglyceride, cetearyl alcohol, cyclopentasiloxane, cetylhexylhexanoate, cyclohexasiloxane, caprylylglycol, trioctanoin, cetyl octanoate, stearic acid, Cyclomethicone, shea butter, lanolin, dimethicone, and the like.

As the pH adjusting agent, triethanolamine, citric acid, sodium citrate, malic acid, sodium malate, fumaric acid, sodium fumarate, succinic acid, sodium succinate, sodium hydroxide, sodium monohydrogen phosphate and the like can be used.

Examples of the thickener include carbomer, hydroxyethyl methacrylate / sodium acryloyldimethyl thioureate copolymer, etc. As the chelating agent, disodium edetate may be used. Examples of the solvent include purified water, 1,2-hexane Diol, and the like.

Hereinafter, the present invention will be described in more detail by way of examples. It will be apparent to those skilled in the art that these embodiments are merely illustrative of the present invention and that the scope of the present invention is not limited to these embodiments.

< Example  1> Arbutin, Niacinamide  And plant extract Cosmetics  Composition manufacturing

100 g of completely dried aloe vera leaves were pulverized and then extracted with 1 L of 70% ethanol (EtOH) aqueous solution using a solvent extraction method. The extracts were prepared by stirring for 48 hours using an agitator to increase the extraction efficiency. This was concentrated under reduced pressure at 50 DEG C or below and then lyophilized to obtain a powdery aloe vera leaf extract.

Using the same method as above, acerola extract, green tea leaf extract and broccoli extract were obtained.

Cosmetic composition (Example 1) was prepared with the obtained extract, arbutin and niacinamide in the composition shown in Table 1 below.

division Component (% by weight) Example 1 A Arbutin 5.00 Niacinamide 2.00 Aloe vera leaf extract 0.10 Acerola extract 0.10 Green tea leaf extract 0.10 Broccoli extract 0.10 B glycerin 5.00 Butylene glycol 2.00 Caprylic / capric triglyceride 4.00 Cetearyl alcohol 2.00 Cyclopentasiloxane 1.50 Cetyl hexanoate 1.00 Glyceryl stearate 2.00 FAGE-40 stearate 1.00 C Spices a very small amount Purified water Balance Sum 100.00

< Example  2> arbutin, Niacinamide , Plant extracts, Mr. Jooba  Preparation of cosmetic composition containing oil and amino acid complex

Amino acid complexes were prepared by mixing equal amounts of lysine, histidine, arginine, aspartic acid, threonine, serine, glutamic acid, proline glycine, alanine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine and cysteine.

The cosmetic composition (Example 2) was prepared from the amino acid complex and the jojoba seed oil, the extract obtained in Example 1, arbutin and niacinamide in the composition shown in Table 2 below.

division Component (% by weight) Example 2 A Arbutin 5.00 Niacinamide 2.00 Aloe vera leaf extract 0.10 Acerola extract 0.10 Green tea leaf extract 0.10 Broccoli extract 0.10 Jojoba seed oil 1.00 Amino acid complex 0.17 B glycerin 5.00 Butylene glycol 2.00 Caprylic / capric triglyceride 4.00 Cetearyl alcohol 2.00 Cyclopentasiloxane 1.50 Cetyl hexanoate 1.00 Glyceryl stearate 2.00 FAGE-40 stearate 1.00 C Spices a very small amount Purified water Balance Sum 100.00

< Comparative Example  1> Arbutin and Niacin Amide  contain Cosmetics  Composition manufacturing

The cosmetic compositions (Comparative Examples 1 to 3) were prepared from the plant extracts, arbutin, niacinamide, jojoba seed oil and amino acid complexes of Example 1 or Example 2 in the composition shown in Table 3 below.

division Component (% by weight) Comparative Example 1 Comparative Example 2 Comparative Example 3 A Arbutin 5.00 5.00 5.00 Niacinamide 2.00 2.00 2.00 Aloe vera leaf extract - 0.10 - Acerola extract - 0.10 0.10 Green tea leaf extract - - 0.10 Broccoli extract - - 0.10 Jojoba seed oil - 1.00 - Amino acid complex - - 0.17 B glycerin 5.00 5.00 5.00 Butylene glycol 2.00 2.00 2.00 Caprylic / capric triglyceride 4.00 4.00 4.00 Cetearyl alcohol 2.00 2.00 2.00 Cyclopentasiloxane 1.50 1.50 1.50 Cetyl hexanoate 1.00 1.00 1.00 Glyceryl stearate 2.00 2.00 2.00 FAGE-40 stearate 1.00 1.00 1.00 C Spices a very small amount a very small amount a very small amount Purified water Balance Balance Balance Sum 100.00 100.00 100.00

< Experimental Example  1> Cosmetics  Whitening effect of composition and analysis of skin irritation

To confirm the whitening effect of the cosmetic compositions of Examples 1 and 2 and Comparative Examples 1 to 3, artificial pigmentation was induced in women 19 to 22 years old with healthy skin selected randomly, After using the above-mentioned cosmetic composition for weeks, skin whitening effect and skin irritation were evaluated.

Specifically, skin whitening effect was evaluated before use of the cosmetic composition and at 1, 2, 4, and 6 weeks after use. The criteria for evaluation were 1 to 7 points, 0 for no pigmentation, 1 for no or light pigmentation, 2 for light pigmentation, 3 for light or moderate pigmentation 4 points for 'normal pigmentation', 5 points for 'normal or severe pigmentation', 6 points for 'severe pigmentation', and 7 points for 'very severe pigmentation'. Two observers evaluated the whitening effect of each cosmetic composition at each time point, and the experimental results are shown in the following Tables 4 and 5 as the average scores of the subjects to be evaluated. Table 4 shows the results of visual evaluation by observer 1, and Table 5 shows results of visual evaluation by observer 2. The presence or absence of skin irritation was evaluated by (number of stimuli) / (total number of test subjects).

division N 0 weeks 1 week 2 weeks 4 weeks 6 weeks Skin irritation Example 1 10 6.4 5.7 5.1 4.5 3.6 2/10 Example 2 10 6.5 5.5 5.0 4.4 3.1 0/10 Comparative Example 1 10 6.5 5.7 5.2 4.6 4.3 8/10 Comparative Example 2 10 6.4 5.8 5.2 4.6 4.2 6/10 Comparative Example 3 10 6.3 5.6 5.3 4.5 4.0 5/10

division N 0 weeks 1 week 2 weeks 4 weeks 6 weeks Skin irritation Example 1 10 6.5 5.4 5.1 4.3 3.2 2/10 Example 2 10 6.5 5.6 5.0 4.2 2.8 0/10 Comparative Example 1 10 6.6 5.7 5.2 4.5 4.2 8/10 Comparative Example 2 10 6.4 5.6 5.1 4.4 4.1 6/10 Comparative Example 3 10 6.4 5.7 5.1 4.4 4.0 5/10

As a result, the cosmetic compositions of Examples 1 and 2 showed a better whitening effect than the cosmetic compositions of Comparative Examples 1 to 3, and it was confirmed that the whitening effect was the most excellent when Example 2 was used .

Even when Comparative Examples 1 to 3 were used, whitening effect was shown. However, when cosmetic compositions containing only arbutin and niacinamide (Comparative Example 1) were used, skin irritation was largely induced, and Comparative Examples 2 and 3 were also used Compared with Examples 1 and 2, stimulation was strong and there was a fear of skin irritation for long-term use. However, the cosmetic composition according to the present invention (Examples 1 and 2) showed little skin irritation. From these results, it was confirmed that the cosmetic composition of Example 1 or 2 not only showed a whitening effect but also relieved skin irritation caused by arbutin and niacinamide.

< Experimental Example  2> Cosmetics  Analysis of skin soothing effect of composition

The present invention relates to a cosmetic composition containing a complex fermented extract according to the present invention and a cosmetic composition containing the complex fermented extract according to the present invention, The degree to which stimulation induced by applying a cosmetic composition not contained was calibrated relative to each other. First, taping was repeated 30 times with a scotch tape on both sides of the underbody to cause skin erythema. After erythema was induced, the cosmetic compositions of Example 1, Example 2 and Comparative Examples 1 to 3 were applied at all times and the degree of skin soothing was evaluated 3 hours after application.

The criteria for evaluation were 1 to 5, 0 for no response, 1 for very mild erythema, 2 for faint or mild erythema, and 1 for weak erythema 4 points for 'marked erythema', and 5 points for 'severe erythema'. The experimental results are shown in Table 6 as the average score of 10 subjects.

division Skin irritation (erythema) degree Left Right Example 1 2.4 2.2 Example 2 0.2 0.3 Comparative Example 1 3.9 3.8 Comparative Example 2 3.3 3.4 Comparative Example 3 3.2 3.1

As shown in Table 6, cosmetic composition containing all of arbutin, niacinamide, aloe vera leaf extract, acerola extract, green tea leaf extract, broccoli extract, jojoba seed oil and amino acid complex according to Example 2 of the present invention , It was confirmed that the skin soothing effect was superior to that of Example 1 or Comparative Example.

< Experimental Example  3> Cosmetics  Analysis of skin soothing effect according to the content of each ingredient in the composition

In order to confirm the skin soothing effect according to the content of each ingredient, the cosmetic composition of Example 2, which has the best skin whitening and skin soothing effect, is selected from aloe vera leaf extract, acerola extract, green tea leaf extract, broccoli extract, Amino acid complexes were prepared in the same manner as in Experimental Example 2, and the skin soothing effects of the respective cosmetic compositions were evaluated in the same manner as in Experimental Example 2. At this time, the contents of the components other than the above components were mixed in the same manner as in Example 2.

(unit:
weight%) Arbutin
Niacinamide
Aloe vera leaf extract Acerola extract
Green tea extract
Broccoli extract
Jojoba seed oil
Amino acid complex
Skin irritation
(Erythema) degree Left Right Example 3 5.00 2.00 0.05 0.10 0.10 0.10 1.00 0.17 2.8 2.9 Example 4 5.00 2.00 0.08 0.10 0.10 0.10 1.00 0.17 0.4 0.5 Example 2 5.00 2.00 0.10 0.10 0.10 0.10 1.00 0.17 0.2 0.3 Example 5 5.00 2.00 0.12 0.10 0.10 0.10 1.00 0.17 0.5 0.4 Example 6 5.00 2.00 0.15 0.10 0.10 0.10 1.00 0.17 2.7 2.6

(unit:
weight%) Arbutin
Niacinamide
Aloe vera leaf extract Acerola extract
Green tea extract
Broccoli extract
Jojoba seed oil
Amino acid complex
Skin irritation
(Erythema) degree Left Right Example 7 5.00 2.00 0.10 0.05 0.10 0.10 1.00 0.17 2.9 3.0 Example 8 5.00 2.00 0.10 0.08 0.10 0.10 1.00 0.17 0.4 0.6 Example 2 5.00 2.00 0.10 0.10 0.10 0.10 1.00 0.17 0.2 0.3 Example 9 5.00 2.00 0.10 0.12 0.10 0.10 1.00 0.17 0.6 0.5 Example 10 5.00 2.00 0.10 0.15 0.10 0.10 1.00 0.17 2.8 2.7

(unit:
weight%) Arbutin
Niacinamide
Aloe vera leaf extract Acerola extract
Green tea extract
Broccoli extract
Jojoba seed oil
Amino acid complex
Skin irritation
(Erythema) degree Left Right Example 11 5.00 2.00 0.10 0.10 0.05 0.10 1.00 0.17 2.7 2.9 Example 12 5.00 2.00 0.10 0.10 0.08 0.10 1.00 0.17 0.4 0.5 Example 2 5.00 2.00 0.10 0.10 0.10 0.10 1.00 0.17 0.2 0.3 Example 13 5.00 2.00 0.10 0.10 0.12 0.10 1.00 0.17 0.5 0.5 Example 14 5.00 2.00 0.10 0.10 0.15 0.10 1.00 0.17 2.8 2.8

(unit:
weight%) Arbutin
Niacinamide
Aloe vera leaf extract Acerola extract
Green tea extract
Broccoli extract
Jojoba seed oil
Amino acid complex
Skin irritation
(Erythema) degree Left Right Example 15 5.00 2.00 0.10 0.10 0.10 0.05 1.00 0.17 2.8 2.7 Example 16 5.00 2.00 0.10 0.10 0.10 0.08 1.00 0.17 0.6 0.5 Example 2 5.00 2.00 0.10 0.10 0.10 0.10 1.00 0.17 0.2 0.3 Example 17 5.00 2.00 0.10 0.10 0.10 0.12 1.00 0.17 0.3 0.4 Example 18 5.00 2.00 0.10 0.10 0.10 0.15 1.00 0.17 2.8 2.9

(unit:
weight%) Arbutin
Niacinamide
Aloe vera leaf extract Acerola extract
Green tea extract
Broccoli extract
Jojoba seed oil
Amino acid complex
Skin irritation
(Erythema) degree Left Right Example 19 5.00 2.00 0.10 0.10 0.10 0.10 0.50 0.17 3.1 3.0 Example 20 5.00 2.00 0.10 0.10 0.10 0.10 0.80 0.17 0.5 0.4 Example 2 5.00 2.00 0.10 0.10 0.10 0.10 1.00 0.17 0.2 0.3 Example 21 5.00 2.00 0.10 0.10 0.10 0.10 1.20 0.17 0.6 0.7 Example 22 5.00 2.00 0.10 0.10 0.10 0.10 1.50 0.17 2.7 2.8

(unit:
weight%) Arbutin
Niacinamide
Aloe vera leaf extract Acerola extract
Green tea extract
Broccoli extract
Jojoba seed oil
Amino acid complex
Skin irritation
(Erythema) degree Left Right Example 23 5.00 2.00 0.10 0.10 0.10 0.10 1.00 0.07 2.9 3.0 Example 24 5.00 2.00 0.10 0.10 0.10 0.10 1.00 0.12 0.3 0.4 Example 2 5.00 2.00 0.10 0.10 0.10 0.10 1.00 0.17 0.2 0.3 Example 25 5.00 2.00 0.10 0.10 0.10 0.10 1.00 0.22 0.5 0.6 Example 26 5.00 2.00 0.10 0.10 0.10 0.10 1.00 0.27 2.8 3.0

As a result, 0.08 to 0.12 wt% of aloe vera leaf extract, 0.08 to 0.12 wt% of acerola extract, 0.08 to 0.12 wt% of green tea extract, 0.08 to 0.12 wt% of broccoli extract, 0.80 to 1.20 wt% of broccoli extract, The present invention relates to a cosmetic composition comprising 0.1% by weight of aloe vera leaf extract, 0.10% by weight of acerola extract, 0.10% by weight of green tea extract, 0.1% by weight of broccoli extract, 0.10 wt.%, Jojoba seed oil 1.00 wt.% And amino acid complex 0.17 wt.%.

The present invention has been described with reference to the preferred embodiments. It will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims. Therefore, the disclosed embodiments should be considered in an illustrative rather than a restrictive sense. The scope of the present invention is defined by the appended claims rather than by the foregoing description, and all differences within the scope of equivalents thereof should be construed as being included in the present invention.

Claims (8)

The extracts of albutin, niacinamide, Aloe barbadensis leaf, Malpighia emarginata fruit, Camellia sinensis leaf and Broccoli (Brassica oleracea var. Italica) Wherein the cosmetic composition is a cosmetic composition for skin whitening. The method according to claim 1,
Wherein the cosmetic composition for skin whitening further comprises a combination of jojoba seed oil (Simmondsia chinensis seed oil) and an amino acid complex. The method according to claim 1,
4.0 to 6.0 parts by weight of arbutin, 1.0 to 3.0 parts by weight of niacinamide, 0.05 to 0.15 part by weight of aloe vera leaf extract, 0.05 to 0.15 part by weight of acerola extract, 0.05 to 0.15 part by weight of green tea leaf extract, 0.15 parts by weight of the extract and 0.05 to 0.15 parts by weight of the broccoli extract. 3. The method of claim 2,
0.5 to 1.5 parts by weight of jojoba seed oil and 0.07 to 0.27 part by weight of amino acid complex based on 100 parts by weight of the total amount of the skin whitening cosmetic composition. 5. The method according to any one of claims 1 to 4,
4.0 to 6.0 parts by weight of arbutin, 1.0 to 3.0 parts by weight of niacinamide, 0.08 to 0.12 part by weight of aloe vera leaf extract, 0.08 to 0.12 part by weight of acerola extract, 0.08 part by weight of green tea leaf extract, 0.12 parts by weight of a broccoli extract, 0.08 to 0.12 parts by weight of a broccoli extract, 0.8-1.2 parts by weight of a jojoba seed oil and 0.12-0.22 parts by weight of an amino acid complex. 3. The method of claim 2,
The amino acid complex may be selected from the group consisting of lysine, histidine, arginine, aspartic acid, threonine, serine, gluamic acid, proline, glycine, (S) selected from the group consisting of alanine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine and cysteine. Wherein the cosmetic composition comprises an amino acid. 3. The method of claim 2,
0.005 to 0.015 parts by weight of lysine, 0.005 to 0.015 part by weight of histidine, 0.005 to 0.015 part by weight of arginine, 0.005 to 0.015 part by weight of aspartic acid, 0.005 to 0.015 part by weight of threonine, 0.005 to 0.015 part by weight of glutamic acid, 0.005 to 0.015 part by weight of proline, 0.005 to 0.015 part by weight of glycine, 0.005 to 0.015 part by weight of alanine, 0.005 to 0.015 part by weight of valine, 0.005 to 0.015 part by weight of methionine, 0.015 to 0.015 part by weight of leucine, 0.005 to 0.015 part by weight of leucine, 0.005 to 0.015 part by weight of tyrosine, 0.005 to 0.015 part by weight of phenylalanine and 0.005 to 0.015 part by weight of cysteine. The method according to claim 1,
The cosmetic composition for skin whitening may be at least one selected from the group consisting of cream, nutritional cream, moisturizing cream, hand cream, massage cream, nutritional lotion, Wherein the composition is at least one formulation selected from the group consisting of a makeup base, a pack, a patch, a gel, a powder, a soap, a cleansing foam, a cleansing lotion, a cleansing cream, a body lotion or a body cleanser.