KR20190016688A - Composition for improvement and prevention of gastroesophageal reflux disease and method for preparing the same - Google Patents

Abstract

The present invention relates to jade salt, which comprises: bay salt; jade powder; and minerals obtained by evaporating water from natural alkaline-reduced water of pH 7.5-8.5 taken from a jade mine area. The present invention provides jade salt, and a method for producing the same, comprising the steps of: (a) mixing 30-55 parts by weight of bay salt, 1-5 parts by weight of jade powder, and 40-65 parts by weight of natural alkaline-reduced water of pH 7.5-8.5 taken from the jade mine area, and heating the same to produce a mixed melt; (b) solidifying the mixed melt produced in the step (a) by cooling; and (c) pulverizing the solidified salt produced in the step (b).

Description

BACKGROUND OF THE INVENTION [0002] The present invention relates to a process for the preparation of a compound of formula

The present invention relates to jade salts and processes for their preparation.

Salt is a substance that is essential for human body. It is not only used as a seasoning in food production, but also promotes metabolism, promotes digestion and supplies minerals. These salts can be roughly divided into sun salt and refined salt.

Among them, the better salt is sun-dried salt, and the sun-dried salt is trapped in the tidal flats and is naturally evaporated. Even if one of sunlight, seawater, tidal-flat, and salt is extinguished,

Salt produced between May and August, which is usually not much difference between day and night, is most suitable for edible because saltiness is strong and bitter taste does not occur.

In Korea, the sea salt erosion is mainly composed of reservoir, evaporation and deciduous ground. It opens the water gate at high tide and creates concentrated salt water from the evaporation ground and sends salt crystals to the crystal ground. If the wind is heavy and the crystal is small, and the temperature is low, the bitter taste or the quality of the salt will be lowered. It is better to pick the salt with a lot of sunshine and low wind.

The salt produced in Korea is alkaline and the salinity is about 88%.

Refined salt is a common salt, and the difference between salt and salt is the difference between natural seasoning and chemical seasoning.

Sun-salt, sea water, and tidal flats, which are made with natural conditions, are rich in minerals such as calcium, magnesium, zinc and potassium. However, since purified water is electrolyzed in ion exchange membrane to obtain sodium chloride and remove impurities, Is 99.8% high salt salt not contained.

Therefore, it is more beneficial to health than salty salts, where sodium chloride accounts for most of the constituents, and a variety of minerals and sodium salts are relatively low.

In addition to sun saliva and tablets, various kinds of processed salt fortified with nutrients or functionalities are distributed on the market. Bamboo salt, which has been used for a long time as a typical example, can be mentioned. In recent years, a method of mixing various materials with salt such as lemon salt and soy sauce salt has been actively studied.

However, when other materials are mixed with salt, the function of the salt itself may be weakened or, in severe cases, salt may be obtained which adversely affects the human body. Therefore, it is necessary to prepare the material through a sufficient test in a hygienic manner.

Korean Patent Publication No. 10-2017-0026850

The object of the present invention is to provide jade salt, jade powder, and jade salt containing minerals obtained by evaporating water from natural alkali reduced water having a pH of 7.5 to 8.5, collected in the jade mine area.

It is another object of the present invention to provide an oxalate obtained by adding a solution of anthraquinone enzyme to the above oxalate.

In order to achieve the above object,

Oxalate containing minerals obtained by evaporation of water from natural alkaline-reduced water of pH 7.5 to 8.5, taken from the sun-salt, jade powder, and jade mine area,

(a) 30 to 55 parts by weight of a salt of austenite, 1 to 5 parts by weight of a jade powder, and 40 to 65 parts by weight of a natural alkali-reduced water having a pH of 7.5 to 8.5, Producing a melt;

(b) cooling the mixed melt produced in step (a) to solidify the mixed melt; And

(c) pulverizing the solid salt prepared in the step (b).

The oxalate

(d) spraying a solution of the crude yam salt with the crude yam powder prepared in step (c) and drying; And

(e) aging the oxalate produced in the step (d).

In addition, the jade powder may be a nephrite powder.

The soybean enzyme solution

(I) 1 to 20% by weight of a bank, 1 to 20% by weight of a bellflower, 1 to 20% by weight of an aroma, 1 to 20% by weight of a crude oil, 1 to 20% 1 to 20% by weight of an acidic garlic, and 1 to 20% by weight of a hymenoptera;

(Ii) adding the sanitary ware washed in step (i) into a jar and adding 10 to 30 parts by weight of sugar which can be a food for the microorganism based on 100 parts by weight of the sanayasia;

(Iii) sealing the jar so that air can pass through and storing the jar in the shade; And

(Iv) squeezing out the fermented residue after 1 to 4 months, and aging for 3 to 10 months.

Further, according to the present invention,

(a) 30 to 55 parts by weight of a salt of austenite, 1 to 5 parts by weight of a jade powder, and 40 to 65 parts by weight of a natural alkali-reduced water having a pH of 7.5 to 8.5, Producing a mixed melt;

(b) cooling and solidifying the mixed melt produced in the step (a); And

and (c) pulverizing the solid salt produced in the step (b).

The process for producing oxalate according to the present invention comprises

(d) spraying and drying a solution of the legume enzyme on the pulverized solid salt prepared in the step (c); And

(e) aging the composition prepared in the step (d).

The oxalate of the present invention exhibits an excellent effect on reflux esophagitis by containing minerals obtained by evaporation of water from sodium salt, jade powder, and natural alkaline-reduced water of pH 7.5 to 8.5 collected in the area of jade mine. It also has excellent effects on strengthening the stomach, strengthening the detoxification, increasing the leukocyte, blood circulation, inflammation, improving the constitution, eliminating the smell, fever and promoting appetite.

In addition, it further enhances the effect when it further comprises a solution of the genus Sanjay enzyme.

Hereinafter, preferred embodiments of the present invention will be described with reference to the accompanying drawings. Prior to the description of the present invention, terms and words used in the present specification and claims to be described below should not be construed as limited to ordinary or dictionary terms. Therefore, the embodiments described in this specification and the configurations shown in the drawings are merely the most preferred embodiments of the present invention and do not represent all the technical ideas of the present invention. Therefore, It is to be understood that equivalents and modifications are possible.

The present invention is an oxalate containing minerals obtained by evaporating water from natural alkaline-reduced water having a pH of 7.5 to 8.5,

(a) 30 to 55 parts by weight of a salt of austenite, 1 to 5 parts by weight of a jade powder, and 40 to 65 parts by weight of a natural alkali-reduced water having a pH of 7.5 to 8.5, Producing a melt;

(b) cooling the mixed melt produced in step (a) to solidify the mixed melt; And

(c) pulverizing the solid salt produced in the step (b).

The oxalate

(d) spraying and drying a solution of the legume enzyme on the pulverized solid salt prepared in the step (c); And

(e) aging the composition prepared in the step (d).

The oxalate of the present invention shows an excellent effect on the reflux esophagitis. It also provides the following benefits:

1) Improvement of gastrointestinal diseases

Jade salt strengthens the stomach, which is the source of health, and provides a pharmacological effect to cure inflammatory diseases.

2) strong detoxification action

Jade salt removes toxins from our bodies. The strong detoxifying action of the jade salt is effective for the treatment of various diseases by washing the body poisoning rapidly (it is good for various allergies such as rhinitis, asthma, atopy).

3) Leukocyte enhancement and sterilization of germs

Jade salt plays an important role in increasing the number of white blood cells consuming germs and enhancing bactericidal power.

4)

Jade salt cleanses the blood, so it treats all diseases sickly and prevents various diseases.

5) Anti-inflammatory action

Jade salt has excellent efficacy in removing inflammation. Spread the jade salt directly on the affected area, the inflammation will be better.

6) Improvement of constitution

The jade salt turns the acidic constitution into a slightly alkaline constitution. These words soon develop immunity and resistance, which makes them stronger and more rigid than any disease.

7) Air purification and deodorization

Jade salt is also used as a pesticide because it is a medicine for humans, but poisonous for pests. Various pollution foods, alcohol, tobacco, medicine, etc., accumulate waste in the body, and odor comes from the mouth and body. It removes the waste accumulated in the body, so it helps modern people suffering from civilization.

8)

When bacteria accumulate and inflammation occurs, heat is generated.

9) Promotes appetite

Jade salt produces stomach acid which is the raw material of stomach juice and improves appetite because it promotes digestion of food.

As the above-mentioned octane powder, a nephrite powder may be preferably used.

When the wound is scratched for several days with a nephrite powder, the main component of the nephrite is consistent with each element of the body, such as scars disappear and the skin is enriched. Is known to exert excellent efficacy.

The far-infrared rays inside the jade are effective for prevention of various adult diseases because the blood circulation of the body is energized and the heat is applied to the inside of the body. Further, the far-infrared rays function to maximize the activity of other components in the toothpaste.

According to Donguibogam, it makes the corn germs softer and makes the corn germs more radiant, expels waste in the body, eliminates the heat of the stomach and is effective in the digestive system. Also, when the corn is ingested, it becomes lighter and easier. It lubricates, helps the voice of the vocal cords, and is described as good for the throat.

It is preferable that the nephrite powder can be produced by using nephrite treated with remnants or wastes derived from mines or gemstones.

The average particle size of the nephrite powder may be 100 to 300 mesh.

The oxalate of the present invention is characterized in that it is prepared using a natural alkali reduced water (aka, 'oak water') having a pH of 7.5 to 8.5, which is collected in the above mine area. In other words, by adding the natural alkaline reducing water of pH 7.5 ~ 8.5 collected in the jade mine area and evaporating all pure water components, beneficial components such as minerals and minerals contained in the natural alkaline reducing water of pH 7.5-8.5 Can be included in all of the oxalates to be produced.

Groundwater produced in the Jade Mine area can be used as the natural alkaline water of pH 7.5 ~ 8.5 collected from the Jade mine area. The groundwater produced in the Jade Mine area is characterized by the mild nature of the water, its taste, and its clean nature. In addition, when people eat for a long time, the five-legged meat becomes rich, the waste in the body escapes, and the hair is not whitened. It is said that Chinese people have always been prone to jade because they have been directly influenced by the human body, stabilizing the nervous system and strengthening the functions of the five muscles.

Natural Alkali Reduced Water is water that is rarely known even in academia because it is rare in the world. In Korea or Japan, alkaline water is usually divided into alkaline water, which is produced by ionized water. Alkaline water is effective in chronic diarrhea, gastritis, gastric hyperplasia, dyspepsia, abnormal gastric fermentation, constipation, relieving fatigue, preventing colds, restoring appetite, hypertension, diabetes, allergies, rheumatism, relieving hangover, asthma and urticaria.

Most preferred is the use of the natural alkaline-reduced water of pH 7.5-8.5 taken from the above-mentioned jade mine area for the production of the jade salt of the present invention. However, natural alkaline reducing water having a natural pH of 7.5 to 8.5 may be used in the present invention.

The pH of the natural alkali reduced water is more preferably 8.0 to 8.5.

The soybean enzyme solution

(I) 1 to 20% by weight of a bank, 1 to 20% by weight of a bellflower, 1 to 20% by weight of an aroma, 1 to 20% by weight of a crude oil, 1 to 20% 1 to 20% by weight of an acidic garlic, and 1 to 20% by weight of a hymenoptera;

(Ii) adding the sanitary ware washed in step (i) into a jar and adding 10 to 30 parts by weight of sugar which can be a food for the microorganism based on 100 parts by weight of the sanayasia;

(Iii) sealing the jar so that air can pass through and storing the jar in the shade; And

(Iv) squeezing out the fermented fermented product after 1 to 4 months, and aging for 3 to 10 months.

The saccharide may be a mixture of honey and sugar at a weight ratio of 1: 3: 1 ~ 3.

It is preferable that the artillery yam is pushed back and forth, and it is preferable to invert the artillery yam once every 2 to 6 weeks.

Although no separate microorganism is added in the above method, known microorganisms used in this field may be added in the step (ii).

The plant fermentation enzyme solution may be sprayed in an amount of 2 to 15% by weight based on the total weight of the pulverized solid composition in the step (d).

The oxalate of the present invention may be a health functional food composition. The oxalate itself can be used as a health functional food composition, and can be prepared in various forms by further adding a carrier, an excipient, or a diluent. Examples of the carrier, excipient and diluent include crystalline glucose, trehalose, xanthan gum, gum arabic, guar gum, skim milk powder, maltodextrin, gelatin, lactose, dextrose, sucrose, sorbitol, mannitol, xylitol, erythritol, maltitol, starch, The present invention relates to a method for producing a microcapsule comprising a microcapsule containing at least one selected from the group consisting of acacia rubber, alginate, calcium phosphate, calcium silicate, cellulose, methylcellulose, microcrystalline cellulose, polyvinylpyrrolidone, water, methylhydroxybenzoate, propylhydroxybenzoate, talc, magnesium stearate, .

The health functional food composition may be formulated in the form of powders, granules, tablets, capsules, suspensions, emulsions, syrups, solutions, expansions, tea, jellies, aerosols, drinks and the like.

The health functional food composition may contain various nutrients, vitamins, minerals (electrolytes), flavors such as synthetic flavors and natural flavors, colorants and heavies (cheese, chocolate etc.), pectic acid and its salts, alginic acid and its salts , Organic acids, protective colloid thickeners, pH adjusting agents, stabilizers, preservatives, glycerin, alcohols, carbonating agents used in carbonated drinks, and the like.

The present invention also relates to

(a) 30 to 55 parts by weight of a salt of austenite, 1 to 5 parts by weight of a jade powder, and 40 to 65 parts by weight of a natural alkali-reduced water having a pH of 7.5 to 8.5, Producing a mixed melt;

(b) cooling and solidifying the mixed melt produced in the step (a); And

and (c) pulverizing the solid salt prepared in the step (b).

The production method of the above oxalate

(d) spraying and drying a solution of the legume enzyme on the pulverized solid salt prepared in the step (c); And

(e) aging the composition prepared in step (d).

All of the above-mentioned contents of the above-mentioned oxalate can be applied to the above-mentioned production method. Therefore, duplicate content is omitted.

The dose of the oxazatol of the present invention is not particularly limited, but it is preferable that the daily dose does not exceed 50 g, and it is preferable to take 1 to 5 g at a time frequently without water or with water frequently.

Hereinafter, the present invention will be described in more detail by way of examples, but the present invention is not limited to the following examples.

Manufacturing example  1: Sanayachi Enzyme solution  Produce

10 wt.% Of bank, 10 wt.% Of anchovy, 10 wt.% Of sea tangle, 10 wt.% Of dodeca, 10 wt.% Of mulberry, 10 wt. I completely removed the water.

The washed yamatsu yamatsu were placed in a dried jar and 20 parts by weight of honey and brown sugar as a sugar which can be fed to microorganisms were added at a weight ratio of 1: 1 based on 100 parts by weight of the yamatsuya. Then the jar was sealed to allow air to pass through and stored in the shade. It was fermented for 3 months while giving back to the farmland once a month. Then, the fermented residue was squeezed out and squeezed for 9 months to prepare a solution of Sanjayo enzyme.

Example  One: Jade salt

150 g of nephrite powder having an average particle size of 200 mesh in 5 kg of sun salts and 5 liters of natural alkaline reducing water of pH 7.5-8.5, manufactured by Daeil Mining Co., Ltd., were taken and mixed well. Next, the cauldron was heated to 850 to 900 DEG C to prepare a mixed melt, followed by cooling and solidification. The solid composition prepared above was ground to produce oxalate.

Example  2: Jade salt (Sanayachi Enzyme solution  adding)

150 g of nephrite powder having an average particle size of 200 mesh in 5 kg of sun salts and 5 liters of natural alkaline reducing water of pH 7.5-8.5, manufactured by Daeil Mining Co., Ltd., were taken and mixed well. Next, the cauldron was heated to 850 to 900 DEG C to prepare a mixed melt, followed by cooling and solidification. After the solid composition prepared above was pulverized, 500 ml of the crude oil solution prepared in Preparation Example 1 was sprayed on the pulverized solid composition and dried. Next, the dried pulverized solid composition was aged for three months in the absence of direct sunlight to produce oxalate.

Test Example : Jade  Effect evaluation

10 male and 10 female subjects with symptoms of reflux esophagitis were selected as the experimental group. The oxalate prepared in Examples 1 and 2 was administered at intervals of 2 to 3 hours with 1.5 g / The degree of improvement of reflux esophagitis was evaluated on days 10, 20, and 30, and the results are shown in Table 1 below. As a control group, one adult male and one female with symptoms of reflux esophagitis were treated with bamboo salt in the same manner as above, and the degree of improvement was evaluated.

<Evaluation Criteria>

◎: 80% improved

○: 50% improved

△: 20% improvement

X: No change

××: worse

Subject After 10 days After 20 days After 30 days Control Male 1 × △ △ Control Female 1 × × △ Male 1 (Example 1 taking oxalate) △ ○ ◎ Male 2 (Example 1 taking oxalate) △ △ ○ Male 3 (Example 1 oxo-salt administration) △ ○ ○ Male 4 (Example 2 taking oxalate) △ ○ ◎ Male 5 (Example 2 taking oxo-salt) △ ○ ◎ Female 1 (Example 1 oxo-salt ingestion) △ ○ ◎ Female 2 (Example 1 oxo-salt ingestion) △ △ ○ Female 3 (Example 1 oxo-salt ingestion) △ ○ ○ Female 4 (Example 2 taking oxo-salt) △ ○ ◎ Female 5 (Example 2 taking oxo-salt) △ ○ ◎

From the results shown in the above Table 1, it was confirmed that the subjects receiving the oxalate according to the present invention had significantly improved reflux esophagitis than the control subjects taking bamboo salt only. No side effects were observed at all.

Claims (6)

Oxalate containing minerals obtained by evaporation of water from natural alkaline-reduced water of pH 7.5 to 8.5, taken from the sun-salt, jade powder, and jade mine area,
(a) 30 to 55 parts by weight of a salt of austenite, 1 to 5 parts by weight of a jade powder, and 40 to 65 parts by weight of a natural alkali-reduced water having a pH of 7.5 to 8.5, Producing a melt;
(b) cooling the mixed melt produced in step (a) to solidify the mixed melt; And
(c) pulverizing the solid salt prepared in the step (b). The method according to claim 1,
(d) spraying a solution of the crude yam salt with the crude yam powder prepared in step (c) and drying; And
(e) aging the oxalate prepared in the step (d). The method according to claim 1,
Wherein the jade powder is a nephrite powder. The method of claim 2,
The soybean enzyme solution
(I) 1 to 20% by weight of a bank, 1 to 20% by weight of a bellflower, 1 to 20% by weight of an aroma, 1 to 20% by weight of a crude oil, 1 to 20% 1 to 20% by weight of an acidic garlic, and 1 to 20% by weight of a hymenoptera;
(Ii) adding the sanitary ware washed in step (i) into a jar and adding 10 to 30 parts by weight of sugar which can be a food for the microorganism based on 100 parts by weight of the sanayasia;
(Iii) sealing the jar so that air can pass through and storing the jar in the shade; And
(Iv) squeezing out the fermented fermented product after 1 to 4 months, and aging the product for 3 to 10 months. (a) 30 to 55 parts by weight of a salt of austenite, 1 to 5 parts by weight of a jade powder, and 40 to 65 parts by weight of a natural alkali-reduced water having a pH of 7.5 to 8.5, Producing a mixed melt;
(b) cooling and solidifying the mixed melt produced in the step (a); And
(c) pulverizing the solid salt produced in the step (b). The method of claim 5,
(d) spraying and drying a solution of the legume enzyme on the pulverized solid salt prepared in the step (c); And
(e) aging the composition prepared in the step (d).