KR20190016507A - TGFβRII의 프레임시프트 돌연변이체를 인식하는 T-세포 수용체 - Google Patents
TGFβRII의 프레임시프트 돌연변이체를 인식하는 T-세포 수용체 Download PDFInfo
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K14/495—Transforming growth factor [TGF]
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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| PCT/EP2017/061087 WO2017194555A1 (en) | 2016-05-09 | 2017-05-09 | T-CELL RECEPTORS WHICH RECOGNISE FRAMESHIFT MUTANTS OF TGFßRII |
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| US10724043B2 (en) * | 2016-10-06 | 2020-07-28 | Nantbio, Inc. | Multi-pulse transfection methods and cells |
| WO2018104473A1 (en) | 2016-12-07 | 2018-06-14 | Oslo Universitetssykehus Hf | Compositions and methods for cell therapy |
| GB201713078D0 (en) * | 2017-08-15 | 2017-09-27 | Adaptimmune Ltd | T Cell Modification |
| EP3692058A1 (en) * | 2017-10-06 | 2020-08-12 | Oslo Universitetssykehus HF | Chimeric antigen receptors |
| SG11202102903QA (en) | 2018-09-21 | 2021-04-29 | Xlifesc Ltd | High affinity t cell receptor for recognizing afp antigen |
| US20220193137A1 (en) * | 2019-04-04 | 2022-06-23 | Umc Utrecht Holding B.V. | Modified immune receptor constructs |
| GB201907663D0 (en) | 2019-05-30 | 2019-07-17 | Ab Mavatar | Method for diagnosing colorectal cancer |
| AU2021351710A1 (en) * | 2020-10-02 | 2023-06-08 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Hla class ii-restricted dq t cell receptors against ras with g13d mutation |
| WO2023050063A1 (zh) * | 2021-09-28 | 2023-04-06 | 溧阳瑅赛生物医药有限公司 | 一种识别hla-a*02:01/e629-38的tcr及其应用 |
| WO2024050399A1 (en) | 2022-09-01 | 2024-03-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Single domain antibodies targeting hpv e6/e7 oncogenic peptide/mhc complexes |
| WO2024263818A2 (en) * | 2023-06-20 | 2024-12-26 | Immunova Therapeutics Llc | Synthetic t cell receptors for enhancing memory (stem) t cells using new transmembranes and signaling domains |
| WO2024260454A1 (zh) * | 2023-06-21 | 2024-12-26 | 北京可瑞生物科技有限公司 | 经修饰的tcr恒定区及其在tcr融合蛋白中的用途 |
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| NO315238B1 (no) * | 1998-05-08 | 2003-08-04 | Gemvax As | Peptider som stammer fra leserammeforskyvingsmutasjoner i TBF<beta>II- eller BAX-genet, og farmasöytiske sammensetninger inneholdende disse,nukleinsyresekvenser som koder for slike peptider, plasmider og virusvektoreromfattende slikenukleinsy |
| FR2779432A1 (fr) * | 1998-06-08 | 1999-12-03 | Transgene Sa | Sequence nucleique du recepteur rii du tgfb, peptide code, et utilisations |
| AU2010277629B2 (en) * | 2009-07-29 | 2016-05-19 | Glaxo Group Limited | Anti - TGF - beta receptor type II single domain antibodies |
| AU2012261933B2 (en) * | 2011-06-03 | 2017-06-15 | Xoma Technology Ltd. | Antibodies specific for TGF-beta |
| US9764037B2 (en) * | 2012-12-06 | 2017-09-19 | Victoria Link Limited | Conjugate compounds |
| WO2015169853A1 (en) * | 2014-05-06 | 2015-11-12 | Universitetet I Oslo | Engineered invariant chain molecule for improved mhc class i loading |
| WO2015189267A2 (en) * | 2014-06-10 | 2015-12-17 | Universitetet I Oslo | Engineered invariant chain molecule for improved mhc class i loading |
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| EP3455249A1 (en) | 2019-03-20 |
| WO2017194555A1 (en) | 2017-11-16 |
| GB201608052D0 (en) | 2016-06-22 |
| CA3024555A1 (en) | 2017-11-16 |
| EA201892217A1 (ru) | 2019-08-30 |
| US20190336529A1 (en) | 2019-11-07 |
| EP3455249B1 (en) | 2023-05-03 |
| MX2018013581A (es) | 2019-07-04 |
| JP2019517790A (ja) | 2019-06-27 |
| CN109328196B (zh) | 2022-11-01 |
| AU2017261684A1 (en) | 2018-12-13 |
| CN109328196A (zh) | 2019-02-12 |
| IL262873A (en) | 2019-01-31 |
| SG11201809716VA (en) | 2018-11-29 |
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