KR20180086301A - 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성 - Google Patents

기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성 Download PDF

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KR20180086301A
KR20180086301A KR1020187021160A KR20187021160A KR20180086301A KR 20180086301 A KR20180086301 A KR 20180086301A KR 1020187021160 A KR1020187021160 A KR 1020187021160A KR 20187021160 A KR20187021160 A KR 20187021160A KR 20180086301 A KR20180086301 A KR 20180086301A
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cells
platelets
stem cells
medium
megakaryocytes
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Korean (ko)
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펭 리
쉬-지앙 루
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스템 셀 앤드 리제너러티브 메디신 인터내셔날, 인크.
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    • C12N5/0644Platelets; Megakaryocytes
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KR1020187021160A 2009-12-04 2010-12-03 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성 Ceased KR20180086301A (ko)

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US26693909P 2009-12-04 2009-12-04
US61/266,939 2009-12-04
US38416510P 2010-09-17 2010-09-17
US61/384,165 2010-09-17
PCT/US2010/058990 WO2011069127A1 (en) 2009-12-04 2010-12-03 Large scale generation of functional megakaryocytes and platelets from human embryonic stem cells under stromal-free conditions

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KR1020127017368A Division KR20120128605A (ko) 2009-12-04 2010-12-03 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성

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KR1020197037186A Division KR20190142424A (ko) 2009-12-04 2010-12-03 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성

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KR1020187021160A Ceased KR20180086301A (ko) 2009-12-04 2010-12-03 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성
KR1020197037186A Ceased KR20190142424A (ko) 2009-12-04 2010-12-03 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성
KR1020127017368A Ceased KR20120128605A (ko) 2009-12-04 2010-12-03 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성
KR1020217016080A Ceased KR20210066020A (ko) 2009-12-04 2010-12-03 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성

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KR1020197037186A Ceased KR20190142424A (ko) 2009-12-04 2010-12-03 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성
KR1020127017368A Ceased KR20120128605A (ko) 2009-12-04 2010-12-03 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성
KR1020217016080A Ceased KR20210066020A (ko) 2009-12-04 2010-12-03 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성

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US (2) US9988603B2 (enExample)
EP (1) EP2507359A4 (enExample)
JP (4) JP2013512676A (enExample)
KR (4) KR20180086301A (enExample)
AU (4) AU2010325811A1 (enExample)
BR (1) BR112012013497A2 (enExample)
CA (2) CA3115233A1 (enExample)
IN (1) IN2012DN05054A (enExample)
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KR20230145494A (ko) 2006-04-14 2023-10-17 아스텔라스 인스티튜트 포 리제너러티브 메디슨 혈관 콜로니 형성 세포
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TWI812867B (zh) 2011-11-30 2023-08-21 安斯泰來再生醫藥協會 利用血管母細胞產生間葉基質細胞之方法
GB201210857D0 (en) 2012-06-19 2012-08-01 Cambridge Entpr Ltd Transcription factor mediated programming towards megakaryocytes
CA2876499C (en) 2012-07-12 2021-10-26 Imstem Biotechnology, Inc. Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof
US9074186B2 (en) 2012-08-15 2015-07-07 Boston Medical Center Corporation Production of red blood cells and platelets from stem cells
CN105101979B (zh) * 2012-12-21 2021-10-08 安斯泰来再生医药协会 由多能干细胞制备血小板的方法及其组合物
JP6580329B2 (ja) 2014-03-31 2019-09-25 シスメックス株式会社 未分化細胞から分化細胞および/または分化細胞の産生物を取得する方法
US10538738B2 (en) 2014-05-19 2020-01-21 Eleftherios Papoutsakis Megakaryocytic particles and microparticles for cell therapy and fate modification of stem and progenitor cells
AU2016242823A1 (en) * 2015-03-30 2017-09-21 Jeffrey Thomas Loh Methods for producing modified red blood cell compositions, compositions and uses thereof
IL299326A (en) 2015-08-18 2023-02-01 Astellas Inst For Regenerative Medicine Clinical formulations
KR102689261B1 (ko) * 2015-10-14 2024-07-30 가부시키가이샤 메가카리온 정제 혈소판의 제조 방법
CA3087344A1 (en) 2018-01-05 2019-07-11 Platelet Biogenesis, Inc. Compositions and methods for producing megakaryocytes
EP3813853A4 (en) 2018-06-29 2022-04-06 Platelet Biogenesis, Inc. DELIVERY COMPOSITIONS AND METHODS OF USE
JP2023526308A (ja) 2020-05-11 2023-06-21 ストーム バイオ インコーポレイテッド 巨核球由来細胞外小胞に関連する組成物及び方法
CA3213792A1 (en) 2021-04-26 2022-11-03 Jonathan Thon Compositions and methods related to megakaryocyte-derived extracellular vesicles for fanconi anemia

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WO2003004995A2 (en) * 2001-01-29 2003-01-16 Rich Ivan N High-throughput stem cell assay of hematopoietic stem and progenitor cell proliferation
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AU2017201995B2 (en) 2019-06-06
JP2016135138A (ja) 2016-07-28
JP2019122385A (ja) 2019-07-25
BR112012013497A2 (pt) 2016-05-31
KR20190142424A (ko) 2019-12-26
WO2011069127A1 (en) 2011-06-09
JP2022064953A (ja) 2022-04-26
EP2507359A1 (en) 2012-10-10
IN2012DN05054A (enExample) 2015-10-09
AU2017201995A1 (en) 2017-04-13
AU2010325811A1 (en) 2012-06-21
US9988603B2 (en) 2018-06-05
US20190002829A1 (en) 2019-01-03
RU2012127810A (ru) 2014-01-10
AU2019203670A1 (en) 2019-06-13
US20120315338A1 (en) 2012-12-13
CA2782013C (en) 2021-06-08
CA2782013A1 (en) 2011-06-09
KR20210066020A (ko) 2021-06-04
JP2013512676A (ja) 2013-04-18
KR20120128605A (ko) 2012-11-27
AU2022200188A1 (en) 2022-02-10
EP2507359A4 (en) 2015-05-13
CA3115233A1 (en) 2011-06-09
AU2019203670B2 (en) 2021-10-14

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