KR20180081608A - 항-혈관형성, 항-림프관신생, 및 항-부종성 특성을 가진 펩티드 및 나노입자 제제 - Google Patents

항-혈관형성, 항-림프관신생, 및 항-부종성 특성을 가진 펩티드 및 나노입자 제제 Download PDF

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KR20180081608A
KR20180081608A KR1020187017365A KR20187017365A KR20180081608A KR 20180081608 A KR20180081608 A KR 20180081608A KR 1020187017365 A KR1020187017365 A KR 1020187017365A KR 20187017365 A KR20187017365 A KR 20187017365A KR 20180081608 A KR20180081608 A KR 20180081608A
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peptide
nanoparticle
seq
patient
administered
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에릭 엠. 브레슬러
조던 제이. 그린
니란잔 비. 펜디
알렉산더 에스. 포펠
론 비. 슈믈리
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아스클리픽스 테라퓨틱스, 엘엘씨.
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
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    • A61K47/6931—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer
    • A61K47/6935—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer the polymer being obtained otherwise than by reactions involving carbon to carbon unsaturated bonds, e.g. polyesters, polyamides or polyglycerol
    • A61K47/6937—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer the polymer being obtained otherwise than by reactions involving carbon to carbon unsaturated bonds, e.g. polyesters, polyamides or polyglycerol the polymer being PLGA, PLA or polyglycolic acid
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • C—CHEMISTRY; METALLURGY
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    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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    • C07K7/04—Linear peptides containing only normal peptide links
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    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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KR1020187017365A 2015-11-19 2016-11-18 항-혈관형성, 항-림프관신생, 및 항-부종성 특성을 가진 펩티드 및 나노입자 제제 Withdrawn KR20180081608A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562257569P 2015-11-19 2015-11-19
US62/257,569 2015-11-19
PCT/US2016/062816 WO2017087825A1 (en) 2015-11-19 2016-11-18 Peptides with anti-angiogenic, anti-lymphangiogenic, and anti-edemic properties and nanoparticle formulations

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KR20180081608A true KR20180081608A (ko) 2018-07-16

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US (1) US20180339024A1 (enExample)
EP (1) EP3377080B1 (enExample)
JP (1) JP2018535224A (enExample)
KR (1) KR20180081608A (enExample)
CN (1) CN108883150A (enExample)
AU (1) AU2016358125A1 (enExample)
BR (1) BR112018010052A2 (enExample)
CA (1) CA3005284A1 (enExample)
IL (1) IL259376A (enExample)
MX (1) MX2018006194A (enExample)
SG (2) SG11201804003VA (enExample)
WO (1) WO2017087825A1 (enExample)

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NZ771201A (en) 2017-04-06 2025-01-31 Sustain Holdings Llc Collagen Peptide-Based Medicament Compositions And Devices And Methods Of Production And Use Thereof
EP3661536A4 (en) 2017-08-03 2021-07-21 Asclepix Therapeutics, Inc. PROCESSES FOR IDENTIFYING AND PREPARING PHARMACEUTICAL AGENTS TO ACTIVATE THE TIE2 RECEPTOR
WO2019232203A2 (en) * 2018-05-31 2019-12-05 Yale University Methods and compositions to alleviate vascular permeability
KR20210146352A (ko) * 2019-03-26 2021-12-03 아스클리픽스 테라퓨틱스, 인크. 안구 질환 치료용 조성물 및 방법
PT3958889T (pt) 2019-04-22 2025-04-10 Sustain Holdings Llc Composições de péptidos miméticos de colagénio para o tratamento de uma doença ou perturbação ocular so segmento posterior que envolve a retina, os vasos sanguíneos da retina, os nervos retinianos ou o nervo ótico
US20230086800A1 (en) * 2020-03-06 2023-03-23 The Board Of Trustees Of The Leland Stanford Junior University Antibody fragments conjugated to peg-plga nanoparticles improve immunotherapy against cancer cells
GB202004514D0 (en) 2020-03-27 2020-05-13 Inst De Medicina Molecular Joaeo Lobo Antunes Treatment of Immunosuppressive Cancer

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EP3377080A1 (en) 2018-09-26
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CN108883150A (zh) 2018-11-23
IL259376A (en) 2018-07-31
MX2018006194A (es) 2018-12-06
AU2016358125A1 (en) 2018-07-05
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EP3377080B1 (en) 2024-02-14
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