KR20180077343A - 단백질 가수분해 처리된 폴리펩티드의 제조방법 - Google Patents

단백질 가수분해 처리된 폴리펩티드의 제조방법 Download PDF

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KR20180077343A
KR20180077343A KR1020187018705A KR20187018705A KR20180077343A KR 20180077343 A KR20180077343 A KR 20180077343A KR 1020187018705 A KR1020187018705 A KR 1020187018705A KR 20187018705 A KR20187018705 A KR 20187018705A KR 20180077343 A KR20180077343 A KR 20180077343A
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polypeptide
lys
asn
ile
leu
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안드레아스 럼멜
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입센 바이오이노베이션 리미티드
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
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    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C—CHEMISTRY; METALLURGY
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    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
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    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
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KR1020187018705A 2012-11-21 2012-11-21 단백질 가수분해 처리된 폴리펩티드의 제조방법 Ceased KR20180077343A (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2012/073283 WO2014079495A1 (en) 2012-11-21 2012-11-21 Methods for the manufacture of proteolytically processed polypeptides

Related Parent Applications (1)

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KR1020157004071A Division KR102083371B1 (ko) 2012-11-21 2012-11-21 단백질 가수분해 처리된 폴리펩티드의 제조방법

Publications (1)

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KR20180077343A true KR20180077343A (ko) 2018-07-06

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KR1020187018705A Ceased KR20180077343A (ko) 2012-11-21 2012-11-21 단백질 가수분해 처리된 폴리펩티드의 제조방법
KR1020157004071A Active KR102083371B1 (ko) 2012-11-21 2012-11-21 단백질 가수분해 처리된 폴리펩티드의 제조방법
KR1020177012803A Active KR102083373B1 (ko) 2012-11-21 2012-11-21 단백질 가수분해 처리된 폴리펩티드의 제조방법
KR1020157016356A Ceased KR20150085844A (ko) 2012-11-21 2013-11-21 단백질 가수분해 처리된 폴리펩티드의 제조방법

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KR1020157004071A Active KR102083371B1 (ko) 2012-11-21 2012-11-21 단백질 가수분해 처리된 폴리펩티드의 제조방법
KR1020177012803A Active KR102083373B1 (ko) 2012-11-21 2012-11-21 단백질 가수분해 처리된 폴리펩티드의 제조방법
KR1020157016356A Ceased KR20150085844A (ko) 2012-11-21 2013-11-21 단백질 가수분해 처리된 폴리펩티드의 제조방법

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Country Link
US (4) US10087432B2 (https=)
JP (3) JP6156954B2 (https=)
KR (4) KR20180077343A (https=)
CN (5) CN111454931A (https=)
AR (3) AR093578A1 (https=)
AU (2) AU2012395188B2 (https=)
BR (2) BR112015003591B1 (https=)
CA (2) CA2880897C (https=)
IN (1) IN2015DN01449A (https=)
MX (3) MX363788B (https=)
RU (2) RU2673910C2 (https=)
TW (5) TWI709649B (https=)
UA (2) UA111795C2 (https=)
WO (2) WO2014079495A1 (https=)

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US10408837B2 (en) * 2013-12-09 2019-09-10 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Peptide substrates recognizable by type E botulinum neurotoxin
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GB201517450D0 (en) 2015-10-02 2015-11-18 Ipsen Biopharm Ltd Method
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KR102480965B1 (ko) 2016-09-13 2022-12-26 알레간 인코포레이티드 안정화된 비단백질 클로스트리듐 독소 조성물
JP7524058B2 (ja) * 2017-10-13 2024-07-29 ウィスコンシン アラムニ リサーチ ファンデーション ボツリヌス神経毒素ａサブタイプ６および薬理学的使用方法
US11707510B2 (en) * 2018-02-16 2023-07-25 Preclinics Discovery Gmbh Nucleic acid-based botulinum neurotoxin for therapeutic use
GB201815817D0 (en) 2018-09-28 2018-11-14 Ispen Biopharm Ltd Clostridial neurotoxins comprising and exogenous activation loop
KR102246906B1 (ko) * 2019-04-29 2021-04-30 주식회사 바이오셀트란 피부 또는 세포 투과능이 우수한 피부주름 방지 또는 개선용 화장료 조성물
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