KR20180075537A - 다발성 경화증을 치료하기 위한 방법 - Google Patents

다발성 경화증을 치료하기 위한 방법 Download PDF

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Publication number
KR20180075537A
KR20180075537A KR1020187012496A KR20187012496A KR20180075537A KR 20180075537 A KR20180075537 A KR 20180075537A KR 1020187012496 A KR1020187012496 A KR 1020187012496A KR 20187012496 A KR20187012496 A KR 20187012496A KR 20180075537 A KR20180075537 A KR 20180075537A
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South Korea
Prior art keywords
antibody
exposure
dose
weeks
seq
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Ceased
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KR1020187012496A
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English (en)
Korean (ko)
Inventor
다피트 레페르트
아네-마리 리-크바이-호잉
미셸 리보나티
도나 마스터맨
예안-파울 페펜
크레이그 스미스
알기르다스 요나스 카카리카 바이스코프
지아멩 장
피터 에스. 친
히데키 가렌
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제넨테크, 인크.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57223757&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20180075537(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 제넨테크, 인크. filed Critical 제넨테크, 인크.
Priority to KR1020247020490A priority Critical patent/KR20240107346A/ko
Publication of KR20180075537A publication Critical patent/KR20180075537A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Spinning Or Twisting Of Yarns (AREA)
  • Treatment Of Fiber Materials (AREA)
  • Preliminary Treatment Of Fibers (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
KR1020187012496A 2015-10-06 2016-10-06 다발성 경화증을 치료하기 위한 방법 Ceased KR20180075537A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020247020490A KR20240107346A (ko) 2015-10-06 2016-10-06 다발성 경화증을 치료하기 위한 방법

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US201562238103P 2015-10-06 2015-10-06
US62/238,103 2015-10-06
US201562238674P 2015-10-07 2015-10-07
US62/238,674 2015-10-07
US201562271985P 2015-12-28 2015-12-28
US62/271,985 2015-12-28
US201662296049P 2016-02-16 2016-02-16
US62/296,049 2016-02-16
US201662322734P 2016-04-14 2016-04-14
US62/322,734 2016-04-14
US201662342633P 2016-05-27 2016-05-27
US62/342,633 2016-05-27
US201662355299P 2016-06-27 2016-06-27
US62/355,299 2016-06-27
PCT/US2016/055841 WO2017062682A2 (en) 2015-10-06 2016-10-06 Method for treating multiple sclerosis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020247020490A Division KR20240107346A (ko) 2015-10-06 2016-10-06 다발성 경화증을 치료하기 위한 방법

Publications (1)

Publication Number Publication Date
KR20180075537A true KR20180075537A (ko) 2018-07-04

Family

ID=57223757

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020187012496A Ceased KR20180075537A (ko) 2015-10-06 2016-10-06 다발성 경화증을 치료하기 위한 방법
KR1020247020490A Pending KR20240107346A (ko) 2015-10-06 2016-10-06 다발성 경화증을 치료하기 위한 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020247020490A Pending KR20240107346A (ko) 2015-10-06 2016-10-06 다발성 경화증을 치료하기 위한 방법

Country Status (18)

Country Link
US (3) US20180327505A1 (https=)
EP (3) EP4732904A2 (https=)
JP (4) JP2018529747A (https=)
KR (2) KR20180075537A (https=)
CN (1) CN108431038A (https=)
DK (1) DK3359572T3 (https=)
ES (1) ES3007182T3 (https=)
FI (1) FI3359572T3 (https=)
HK (1) HK1257072A1 (https=)
HR (1) HRP20250052T1 (https=)
HU (1) HUE069935T2 (https=)
IL (3) IL293708B2 (https=)
LT (1) LT3359572T (https=)
PL (1) PL3359572T3 (https=)
PT (1) PT3359572T (https=)
RS (1) RS66408B1 (https=)
SI (1) SI3359572T1 (https=)
WO (1) WO2017062682A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220389109A1 (en) * 2019-09-11 2022-12-08 Novartis Ag Management of conditions other than multiple sclerosis in ofatumumab-treated patients
WO2021173740A1 (en) * 2020-02-28 2021-09-02 Genentech, Inc. Methods of treating primary progressive multiple sclerosis using an inhibitor of bruton's tyrosine kinase
IL300415A (en) * 2020-08-14 2023-04-01 Hoffmann La Roche Methods for treating multiple sclerosis with ocralizumab
CN121358505A (zh) 2023-07-28 2026-01-16 株式会社实瞳 抗棘阿米巴用液剂

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