KR20180027611A - 목시플록사신을 귀에 도포하기 위한 방법 및 조성물 - Google Patents

목시플록사신을 귀에 도포하기 위한 방법 및 조성물 Download PDF

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Publication number
KR20180027611A
KR20180027611A KR1020187005804A KR20187005804A KR20180027611A KR 20180027611 A KR20180027611 A KR 20180027611A KR 1020187005804 A KR1020187005804 A KR 1020187005804A KR 20187005804 A KR20187005804 A KR 20187005804A KR 20180027611 A KR20180027611 A KR 20180027611A
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South Korea
Prior art keywords
moxifloxacin
fluid
eardrum
administration
concentration
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Ceased
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KR1020187005804A
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English (en)
Korean (ko)
Inventor
로날드 제이. 쇼우척
벨린다 더블유.와이. 청
지. 마이클 월
Original Assignee
리전츠 오브 더 유니버스티 오브 미네소타
노파르티스 아게
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44306169&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20180027611(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 리전츠 오브 더 유니버스티 오브 미네소타, 노파르티스 아게 filed Critical 리전츠 오브 더 유니버스티 오브 미네소타
Publication of KR20180027611A publication Critical patent/KR20180027611A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
KR1020187005804A 2010-01-07 2011-01-07 목시플록사신을 귀에 도포하기 위한 방법 및 조성물 Ceased KR20180027611A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29301910P 2010-01-07 2010-01-07
US61/293,019 2010-01-07
PCT/US2011/020531 WO2011085209A2 (en) 2010-01-07 2011-01-07 Methods and compositions for applying moxifloxacin to the ear

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020127020775A Division KR101835895B1 (ko) 2010-01-07 2011-01-07 목시플록사신을 귀에 도포하기 위한 방법 및 조성물

Publications (1)

Publication Number Publication Date
KR20180027611A true KR20180027611A (ko) 2018-03-14

Family

ID=44306169

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020127020775A Expired - Fee Related KR101835895B1 (ko) 2010-01-07 2011-01-07 목시플록사신을 귀에 도포하기 위한 방법 및 조성물
KR1020187005804A Ceased KR20180027611A (ko) 2010-01-07 2011-01-07 목시플록사신을 귀에 도포하기 위한 방법 및 조성물

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1020127020775A Expired - Fee Related KR101835895B1 (ko) 2010-01-07 2011-01-07 목시플록사신을 귀에 도포하기 위한 방법 및 조성물

Country Status (24)

Country Link
US (1) US20120289541A1 (enExample)
EP (2) EP3305280A1 (enExample)
JP (3) JP2013516485A (enExample)
KR (2) KR101835895B1 (enExample)
CN (2) CN106309356A (enExample)
AU (1) AU2011204275B2 (enExample)
BR (1) BR112012016809A2 (enExample)
CA (1) CA2786525A1 (enExample)
CL (1) CL2012001835A1 (enExample)
CY (1) CY1119493T1 (enExample)
DK (1) DK2521547T3 (enExample)
ES (1) ES2644826T3 (enExample)
HR (1) HRP20171592T1 (enExample)
HU (1) HUE035586T2 (enExample)
LT (1) LT2521547T (enExample)
MX (1) MX337419B (enExample)
NO (1) NO2521547T3 (enExample)
PH (1) PH12012501371A1 (enExample)
PL (1) PL2521547T3 (enExample)
PT (1) PT2521547T (enExample)
RU (2) RU2576029C2 (enExample)
SI (1) SI2521547T1 (enExample)
WO (1) WO2011085209A2 (enExample)
ZA (1) ZA201205965B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
EP3995160A1 (en) * 2012-06-28 2022-05-11 The Administrators of the Tulane Educational Fund Selectively polymerizable compositions
CN103869033B (zh) * 2012-12-14 2016-10-05 南京长澳医药科技有限公司 一种液相色谱法分离测定盐酸莫西沙星及其杂质的方法
JP6255134B1 (ja) * 2016-11-02 2017-12-27 ヴェローチェ・バイオファーマ・エルエルシー 耳炎の治療のための組成物および方法
JP7327817B2 (ja) * 2017-12-08 2023-08-16 ザ・ジョンズ・ホプキンス・ユニバーシティー 粘膜表面における活性薬剤の増強された輸送のための低張性ヒドロゲル製剤
CN108593696B (zh) * 2018-04-26 2020-11-03 南京明捷生物医药检测有限公司 一种利用定量核磁测定多肽中三氟乙酸残留的方法
CN117045593B (zh) * 2023-09-19 2024-05-28 上海市第六人民医院 一种用于慢性中耳炎治疗的抗菌温敏水凝胶及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6201072B1 (en) 1997-10-03 2001-03-13 Macromed, Inc. Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
AR020661A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US6740664B2 (en) * 1998-09-30 2004-05-25 Alcon, Inc. Methods for treating otic and ophthalmic infections
JP3450805B2 (ja) * 2000-08-08 2003-09-29 わかもと製薬株式会社 水性医薬組成物
US7220431B2 (en) * 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
WO2006065301A2 (en) * 2004-12-10 2006-06-22 Alcon, Inc. Compositions for treatment of ear infections
US8822410B2 (en) * 2008-05-19 2014-09-02 Children's Medical Center Corporation Tympanic membrane permeating ear drops and uses thereof

Also Published As

Publication number Publication date
PT2521547T (pt) 2017-11-17
KR20120114344A (ko) 2012-10-16
CN106309356A (zh) 2017-01-11
LT2521547T (lt) 2017-12-11
ES2644826T3 (es) 2017-11-30
EP2521547A2 (en) 2012-11-14
EP2521547A4 (en) 2014-03-26
PL2521547T3 (pl) 2018-01-31
CL2012001835A1 (es) 2013-03-22
CY1119493T1 (el) 2018-03-07
JP2013516485A (ja) 2013-05-13
HRP20171592T1 (hr) 2018-02-09
WO2011085209A2 (en) 2011-07-14
RU2016101214A (ru) 2018-11-21
DK2521547T3 (da) 2017-11-20
MX337419B (es) 2016-03-03
RU2012133568A (ru) 2014-02-20
HUE035586T2 (en) 2018-05-28
RU2576029C2 (ru) 2016-02-27
SI2521547T1 (en) 2018-02-28
CA2786525A1 (en) 2011-07-14
JP6267246B2 (ja) 2018-01-24
AU2011204275B2 (en) 2015-04-02
NO2521547T3 (enExample) 2018-01-13
EP2521547B1 (en) 2017-08-16
WO2011085209A3 (en) 2011-11-17
JP2018076352A (ja) 2018-05-17
US20120289541A1 (en) 2012-11-15
BR112012016809A2 (pt) 2017-09-26
PH12012501371A1 (en) 2012-10-22
JP2016155808A (ja) 2016-09-01
AU2011204275A1 (en) 2012-08-23
ZA201205965B (en) 2014-01-29
EP3305280A1 (en) 2018-04-11
MX2012007928A (es) 2012-11-22
KR101835895B1 (ko) 2018-03-07
CN102791270A (zh) 2012-11-21

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