KR20180000513A - Cosmetics Composition - Google Patents
Cosmetics Composition Download PDFInfo
- Publication number
- KR20180000513A KR20180000513A KR1020160078583A KR20160078583A KR20180000513A KR 20180000513 A KR20180000513 A KR 20180000513A KR 1020160078583 A KR1020160078583 A KR 1020160078583A KR 20160078583 A KR20160078583 A KR 20160078583A KR 20180000513 A KR20180000513 A KR 20180000513A
- Authority
- KR
- South Korea
- Prior art keywords
- weight
- parts
- extract
- filtrate
- root
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
Description
The present invention relates to the field of Chinese medicine cosmetics, and more particularly to cosmetic compositions containing herbal extracts.
In modern societies, several factors, such as emotional changes due to work stress, insufficient diet, reduced irregular sleep and in vivo toxicity elimination, may result in insufficient qi-blood circulation, Accumulate and rise to the surface of the skin, thereby generating various color spots.
In addition, other factors such as environmental dust pollution, insufficient recovery after surgery or postpartum, gynecological inflammation, liver and kidney function deficiency, insufficient hemicycle circulation and the like lead to the generation of yellow skin and wrinkles due to deficiency of the supply of blood, I can give trouble to women.
Excretion dysfunction of the liver and spleen may result in the development of papules by closing the skin pits. People with these symptoms are characterized by dysthesia, insomnia, dry mouth, bitter taste, ozostomia, strong body odor, yellow urine, and oily skin.
The above-mentioned color spots, pigmentation, papules, wrinkles and skin characteristics of yellow skin are common in many women, and they have a long-term disease and affect the appearance of the patient, It causes more pain.
Today, many skin care products contain an endless variety of herbal ingredients. However, because the herbal ingredients contained therein have a large molecular weight or other influencing factors, various ingredients of skin care products have incompatible dissolution rates, resulting in inconsistent absorption and poor absorption of herbal skin care products do. Therefore, they have no meaningful skin protection effect and can not exhibit the beneficial effects of whitening, oil control, rejuvenation, allergy resistance, anti-aging, wrinkle removal, and color spots removal.
The present invention is capable of eliminating facial toxins and local pigmentation, eliminating dampness and heat, alleviating dampness and relieving restlessness, A cosmetic composition which can remove, remove skin spots, whiten skin, and restore glossy skin.
The cosmetic composition according to the present invention includes herbal extracts obtained from the following raw materials: Lilium brownii, black sesame seed powder, Radix Stemonae, Folium Artemisiae Argyi, Fructus Gardeniae, Cordyceps sinensis, Radix Paeoniae Alba, Lotus Plumule, Houttuynia cordata, and Thatch root.
Preferably, the herbal extract is obtained from the following ingredients: 4 to 18 parts by weight of a lily, 4 to 18 parts by weight of black sesame seed powder, 4 to 18 parts by weight of a whiteness, 4 to 18 parts by weight of a liana, 4 to 18 parts by weight of Cordyceps sinensis, 4 to 18 parts by weight of peony root, 4 to 18 parts by weight of undiluted root, 4 to 18 parts by weight of cordierite, and 4 to 18 parts by weight of batten root.
Preferably, the medicinal herb extract is obtained from the following raw materials: 5 to 10 parts by weight of lilies, 5 to 10 parts by weight of black sesame seed powder, 5 to 10 parts by weight of backbone, 5 to 10 parts by weight of rhizome, 5 to 10 parts of gardenia 5 to 10 parts by weight of Cordyceps sinensis, 5 to 10 parts by weight of peony root, 5 to 10 parts by weight of mandarin, 5 to 10 parts by weight of cordate, and 1 to 5 parts by weight of batten root.
Preferably, the method for preparing the medicinal herb extract comprises the steps of: mixing and pulverizing raw materials to obtain a medicinal powder; performing supercritical carbon dioxide extraction on the medicinal material powder using anhydrous ethanol as a solvent; Performing vacuum concentration while recirculating to obtain an ethanol extract concentrated solution and a pharma- ceutical residue; Decoction and secondary dehydration of the medicinal material residue using water and water to obtain a first filtrate and a second filtrate, mixing the first filtrate and the second filtrate to obtain a filtrate mixture , The filtrate mixture is concentrated at 50 DEG C to obtain an extract solution having a relative density of 1.30 to 1.50, and the extract solution is dried to obtain a solid extract, and the solid extract is concentrated using a macroporous adsorption resin to obtain a powder And extracting the herbal medicine extract of the present invention by mixing the powder with the ethanol extract concentrated solution, wherein the primary diol is performed for 30 to 50 minutes using water in an amount of 8 to 10 times the weight of the drug residue, Wherein said secondary dessication is performed for 80 to 90 minutes with water in an amount of 9 to 12 times the weight of the pharma- ceutical residue.
Preferably, the carbon dioxide supercritical extraction is carried out at a temperature of 60 to 70 DEG C under a pressure of 30 to 40 MPa for 0.5 to 1 hour.
Preferably, the cosmetic composition may be a cosmetic mask solution, an essence, a skin care condensation, a face cream, and an emulsion.
The cosmetic compositions of the present invention provide a continuous supply of nutrients to the facial skin, are suitable for any skin, and are particularly suitable for dry skin and aged skin.
[Detailed Description of Embodiments]
Hereinafter, specific embodiments of the present invention will be described.
Example One
A herbal extract is obtained from the following ingredients in parts by weight:
5 grams of lily, 5 grams of black sesame seed powder, 5 grams of 5 centipede, 5 grams of louse, 5 grams of gardenia, 5 grams of caterpillar fungus, 5 grams of peony root, 5 grams of seeds, 5 grams of cod liver,
The medicinal material extract is prepared by the following steps: The raw materials are weighed according to their weights, and the raw materials are mixed and pulverized to obtain a medicinal material powder. The medicinal material powder is obtained by using anhydrous ethanol as a solvent at a temperature of 60 DEG C under a pressure of 30 MPa Performing carbon dioxide supercritical extraction on the pharmaceutical powder for 0.5 hours and performing vacuum concentration while recirculating ethanol under a pressure of 10 MPa at a temperature of 20 ° C to obtain an ethanol extract concentrated solution and a medicinal material residue, Ethanol is used as a solvent in an amount of 2 ml / g of the pharmaceutical powder; The first filtrate and the second filtrate are mixed to obtain a filtrate mixture, and the filtrate is subjected to filtration to obtain a filtrate mixture at 50 DEG C Concentrating the filtrate mixture to obtain an extract solution having a relative density of 1.30 to 1.50 and drying the extract solution to obtain a solid extract, wherein the primary diaspore is water in an amount of 8 to 10 times the weight of the drug residue, For 30 minutes to 50 minutes, and the second pouring is carried out using water in an amount of 9 to 12 times the weight of the medicinal material residue for 80 minutes to 90 minutes; The solid extract was diluted with an appropriate amount of water to obtain a solid extract-water mixture. The solid extract-water mixture was uniformly mixed with a D-101 macroporous adsorption resin at a volume ratio of 1: 1, / Resin ratio, or other non-polar, weakly polar or mesoporous macroporous adsorption resin column for 15 minutes followed by collection of 60-70% ethanol eluate Concentrating the solid extract by sequentially eluting with 10 times column volumes of ethanol at different concentrations to obtain a brown powder; And mixing the powder with a pale brown oily ethanol extract concentrated solution obtained from a carbon dioxide supercritical extraction step to obtain a medicinal herb extract of the present invention.
Example 2
10 g of black liquor, 10 g of white sesame seeds, 10 g of lobster, 10 g of gardenia, 10 g of garden mackerel, 10 g of pampas grass, 10 g of uncooked mackerel, 10 g of mung bean sprout, and 5 g of pickled roots are obtained from the following raw materials represented by parts by weight.
The method of producing the medicinal herb extract is the same as that of Example 1.
Example 3
8 g of lily, 8 g of black sesame seed powder, 9 g of white sesame seeds, 5 to 10 g of liana, 6 g of gardenia, 6 g of Chinese caterpillar fungus, 6 g of peony root, 7 g of uncooked root, 8 g of fish sauce and 2 g of pickled root.
The method of producing the medicinal herb extract is the same as that of Example 1.
Example 4
The herb extract is obtained from the following ingredients in weight parts: 9 grams of lilies, 7 grams of black sesame seed powder, 9 grams of backbone, 5 to 10 grams of head lice, 6 grams of gardenia, 6 grams of Chinese cabbage, 8 grams of Chinese cabbage, 7 grams of fresh Chinese cabbage, 8 grams of Chinese cabbage,
The method of producing the medicinal herb extract is the same as that of Example 1.
Example 5
The extract of the medicinal herb is obtained from the following ingredients, expressed in parts by weight: 20 g of lily, 20 g of black sesame seed powder, 30 g of white sesame seeds, 10 g of lobster, 10 g of gardenia, 10 g of caterpillar fungus, 10 g of peony root, 10 g of radish seeds,
The method of producing the medicinal herb extract is the same as that of Example 1.
A chromatosis model induced by UVB is adopted and the herbal extract of the present invention is administered as follows.
Three separate areas (2 x 2 cm 2 ) of the back skin of each guinea pig were selected, and the covered hairs were completely removed. The skin of the area was then treated with SS-04B type ultraviolet light treatment device for 20 minutes at a time 2 weeks to investigate, investigate the dose of 200mJ / cm 2 per day, and check out the accumulated dose of 2800mJ / cm 2 2 weeks. The ultraviolet lamp is equipped with a UVB light source and has a spectral peak value of 310 to 315 nm. Before irradiation, the irradiating light intensity should be measured using a UVB ultraviolet measuring device. The skin of the selected site is administered with the herbal medicine extract of the present invention at 2 hours after the irradiation, and after the completion of the irradiation for 2 weeks, the skin is continuously administered for 2 weeks, and then the skin tissue of the site is examined pathologically.
The number of melanin granule cells and the number of dioxyphenylalanine positive melanin cells for the first group, the second group and the third group are obtained through optical microscopic observation.
The first group of normal guinea pig back skin was used as a control group; The second group of guinea pigs is irradiated with ultraviolet rays but no medicines are administered; Guinea pigs and the like are irradiated with ultraviolet rays, and then the herbal medicine extracts of Examples 1 to 5 are applied at a concentration of 0.5 mg / ml and 1 mg / ml, respectively.
Dyeing method
1) HE staining method: HE stain a skin sample (2 cm x 2 cm) obtained from guinea pigs in the form of a normal paraffin section.
2) Schmorl staining method
The method comprises the steps of: (1) washing the skin slices, such as guinea pigs, with water; (2) The washed guinea pig skin slices were suspended in 30 ml of a newly prepared 0.037mol / L (1%) ferric chloride solution, 4 ml of freshly prepared 0.03mol / L (1%) potassium ferricyanide Treating the mixture with a mixture of 6 ml of distilled water for 10 minutes; And (3) washing with the running water such as the guinea pig treated. As a result, the melanin granule cells are stained with yellowish brown and black.
3) Imokawa dyeing method
(1) A skin sample (2 cm x 2 cm) is taken from a guinea pig back area, the sample is washed with a 0.1 mol / LPBS solution (pH 6.8), the sample is washed with 37 Lt; 0 > C for 5 hours with 1 mol / L sodium bromide solution; (2) separating the epidermis and dermis of the sample; (3) fixing the epidermis with 3.33 mol / L (10%) cold neutral formalin solution, and washing the epidermis twice with 0.1 mol / LPBS solution (pH 6.8); And (4) dyeing the epidermis with 0.1% dioxyphenylalanine (0.1 mol / L PBS solution) (pH 6.8) for 5 hours. As a result, the melanocytes are dyed in dark brown.
Observation through optical microscope
1) Determination of melanin granule cell count: Using Schmorl staining method, the number of melanocyte granules per 1 mm 3 of epidermal basal layer in each sample was measured by a net-shaped eyepiece micrometer single blind method under a high magnification lens .
2) Measurement of dioxyphenylalanine-positive melanocyte count: Using Imokawa staining method, the number of melanocytes positive for dioxyphenylalanine per 1 mm 3 of epidermal basal layer in each sample was measured with a net-shaped eyepiece micro- Meter is measured by a single blind method.
As can be seen from the above Table 1, the number of melanin granule cells and the number of dioxyphenylalanine positive melanin cells in the UVB irradiation group were significantly increased compared to the control group, and the UVB-induced pigmentation Similar) skin model is successfully obtained. The herbal medicine extract of the present invention can significantly reduce the number of melanin granule cells and the number of dioxyphenylalanine-positive melanin cells, so that the herbal medicine extract of the present invention has a good effect of whitening skin and removing color spots Able to know.
While the foregoing embodiments are being used to illustrate the present invention in detail, it should be understood that they are not intended to limit the scope of the present invention, and any equivalents or variations that do not depart from the spirit of the present invention are within the scope of the technical solution of the present invention. do.
Claims (5)
Mixing and pulverizing the raw materials to obtain a pharmaceutical powder, performing supercritical carbon dioxide extraction on the pharmaceutical powder using anhydrous ethanol as a solvent, and performing vacuum concentration while recycling ethanol to obtain an ethanol extract concentrated solution and a pharmaceutical residue step; And
The first filtrate and the second filtrate are mixed to obtain a filtrate mixture, and the filtrate is subjected to filtration to obtain a filtrate mixture at 50 DEG C The filtrate mixture is concentrated to obtain an extract solution having a relative density of 1.30 to 1.50, the extract solution is dried to obtain a solid extract, and the solid extract is concentrated using a macroporous adsorption resin to obtain a powder, Extracting the herbal medicine extract of the present invention by mixing with the ethanol extract concentrated solution, wherein the primary diol is performed for 30 to 50 minutes using water in an amount of 8 to 10 times the weight of the drug residue, Wherein the treatment is carried out for 80 to 90 minutes with water in an amount of 9 to 12 times the weight of the pharmaceutical residue.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020160078583A KR20180000513A (en) | 2016-06-23 | 2016-06-23 | Cosmetics Composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020160078583A KR20180000513A (en) | 2016-06-23 | 2016-06-23 | Cosmetics Composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20180000513A true KR20180000513A (en) | 2018-01-03 |
Family
ID=61002405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020160078583A KR20180000513A (en) | 2016-06-23 | 2016-06-23 | Cosmetics Composition |
Country Status (1)
| Country | Link |
|---|---|
| KR (1) | KR20180000513A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102046167B1 (en) | 2018-05-24 | 2019-11-18 | 농업회사법인 참솔(주) | A functional cosmetic composition comprising the chi-ja fermentation product |
| CN112386622A (en) * | 2020-11-05 | 2021-02-23 | 珀莱雅化妆品股份有限公司 | Preparation method and application of efficient freckle-removing active substance |
-
2016
- 2016-06-23 KR KR1020160078583A patent/KR20180000513A/en unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102046167B1 (en) | 2018-05-24 | 2019-11-18 | 농업회사법인 참솔(주) | A functional cosmetic composition comprising the chi-ja fermentation product |
| CN112386622A (en) * | 2020-11-05 | 2021-02-23 | 珀莱雅化妆品股份有限公司 | Preparation method and application of efficient freckle-removing active substance |
| CN112386622B (en) * | 2020-11-05 | 2021-11-09 | 珀莱雅化妆品股份有限公司 | Preparation method and application of freckle-removing active substance |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104622776B (en) | A kind of cosmetic composition containing Chinese medicine extraction liquid | |
| CN101394900A (en) | Combination or plant extract comprising verbascoside and luteolin and their use in a cosmetically or pharmaceutical composition for pigmentation modulation | |
| CN109602686A (en) | A kind of aqueous gelled cosmetic compositions and preparation method thereof | |
| CN101804185B (en) | Chinese medicinal compound extract for whitening and removing freckles and preparation method thereof | |
| CN104784507A (en) | Traditional Chinese medicine composition with multiple cosmetic effects and application | |
| KR100564108B1 (en) | Cosmetic composition comprising plant extract having anti-aging effect | |
| KR20180000513A (en) | Cosmetics Composition | |
| KR20180000553A (en) | Cosmetics composition | |
| KR100544024B1 (en) | Skin whitening compound | |
| KR100515418B1 (en) | Anti-wrinkle cosmetics composition comprising natural herb extracts | |
| KR101139373B1 (en) | Cosmetic composition for skinwhitening and manufacturing method thereof and mask-pack containing this | |
| CN101360478B (en) | Cosmetic composition containing extracts of pinus koraiensis as active ingredient | |
| CN108938511A (en) | The composition of natural plant extracts and the application in skin moisture-keeping product for resolving poxes | |
| CN104224656B (en) | A kind of electric power work high above the ground anti-sunburn preparation | |
| KR20110063912A (en) | A topical composition comprising the extract of platycodi radix, bupleuri radix and ginseng radix and the purified fractions therefrom inhibiting skin aging and wrinkle formation | |
| KR20180002314A (en) | Cosmetics composition | |
| KR20080111299A (en) | Whitening composition for external applications to the skin containing premature kaempferol-3,7-o-alpha-l-dirhamnopyranoside | |
| CN105616295B (en) | It is a kind of with the folium artemisiae argyi composition of whitening function and its application | |
| KR20180044538A (en) | Facial mask | |
| CN104666147A (en) | Chinese herbal medicine compound for repairing ultraviolet damage and application of Chinese herbal medicine compound in cosmetics | |
| KR20180033673A (en) | Facial mask | |
| CN104188891B (en) | A kind of preparation method of electric operating sunscreen | |
| KR20170142334A (en) | Cosmetics composition | |
| CN108379175A (en) | A kind of preparation method of the suncream containing natural sun-prevention component | |
| KR102137952B1 (en) | Cosmetic composition with skin soothing effect |