KR20170063722A - 선천적 면역 반응의 종양 유도된 면역억제를 차단하기 위한 방법으로서의 아넥신 v의 사용 - Google Patents

선천적 면역 반응의 종양 유도된 면역억제를 차단하기 위한 방법으로서의 아넥신 v의 사용 Download PDF

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KR20170063722A
KR20170063722A KR1020177010186A KR20177010186A KR20170063722A KR 20170063722 A KR20170063722 A KR 20170063722A KR 1020177010186 A KR1020177010186 A KR 1020177010186A KR 20177010186 A KR20177010186 A KR 20177010186A KR 20170063722 A KR20170063722 A KR 20170063722A
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annexin
cancer
tumor
cells
agents
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Korean (ko)
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프란시스 제라드 브란켄버그
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더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티
더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티
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Application filed by 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티, 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 filed Critical 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티
Publication of KR20170063722A publication Critical patent/KR20170063722A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
KR1020177010186A 2014-10-03 2015-10-02 선천적 면역 반응의 종양 유도된 면역억제를 차단하기 위한 방법으로서의 아넥신 v의 사용 Withdrawn KR20170063722A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462059669P 2014-10-03 2014-10-03
US62/059,669 2014-10-03
PCT/US2015/053828 WO2016054574A1 (en) 2014-10-03 2015-10-02 Use of annexin v as a method to block tumor induced immunosuppression of the innate immune response

Publications (1)

Publication Number Publication Date
KR20170063722A true KR20170063722A (ko) 2017-06-08

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KR1020177010186A Withdrawn KR20170063722A (ko) 2014-10-03 2015-10-02 선천적 면역 반응의 종양 유도된 면역억제를 차단하기 위한 방법으로서의 아넥신 v의 사용

Country Status (7)

Country Link
US (1) US11253568B2 (cg-RX-API-DMAC7.html)
EP (1) EP3200811A4 (cg-RX-API-DMAC7.html)
JP (1) JP2017530130A (cg-RX-API-DMAC7.html)
KR (1) KR20170063722A (cg-RX-API-DMAC7.html)
AU (1) AU2015327887A1 (cg-RX-API-DMAC7.html)
CA (1) CA2962255A1 (cg-RX-API-DMAC7.html)
WO (1) WO2016054574A1 (cg-RX-API-DMAC7.html)

Families Citing this family (11)

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Publication number Priority date Publication date Assignee Title
SG175993A1 (en) 2009-05-11 2011-12-29 Berg Biosystems Llc Methods for treatment of metabolic disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers
JP6092844B2 (ja) 2011-04-04 2017-03-08 バーグ エルエルシー 中枢神経系腫瘍の治療方法
MX380565B (es) 2013-04-08 2025-03-12 Berg Llc Terapias combinadas de coenzima q10 para el tratamiento de cáncer.
CN105705162A (zh) 2013-09-04 2016-06-22 博格有限责任公司 通过持续输注辅酶q10来治疗癌症的方法
US20170189350A1 (en) 2015-11-16 2017-07-06 Berg Llc Methods of treatment of temozolomide-resistant glioma using coenzyme q10
US20180021270A1 (en) * 2016-07-21 2018-01-25 Berg Llc Methods for the treatment of cancer using coenzyme q10 in combination with immune checkpoint modulators
US10874711B2 (en) 2017-07-05 2020-12-29 The Board Of Trustees Of The Leland Stanford Junior University Use of annexin V to reduce the spread of intracellular pathogens
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
CA3180886A1 (en) * 2020-07-09 2022-01-13 Cheng Luo Compositions and methods for inhibiting ythdf1
WO2022212352A1 (en) * 2021-03-29 2022-10-06 The Board Of Trustees Of The Leland Stanford Junior University Reversal of ctl exhaustion with annexin v
US20250049884A1 (en) * 2022-01-03 2025-02-13 The Board Of Trustees Of The Leland Stanford Junior University Blocking and reversing extracellular vesicle driven transcriptomic transformation with annexin v treatment

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7262167B2 (en) * 1995-11-06 2007-08-28 Exibona Ltd. Drug, in particular for modulating the immunological response for the control of viruses, tumors, bacteria and parasites
US6818213B1 (en) * 1998-07-13 2004-11-16 Board Of Regents, The University Of Texas System Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids
US7635680B2 (en) * 2001-02-21 2009-12-22 Alavita Pharmaceuticals, Inc. Attenuation of reperfusion injury
DE10145254A1 (de) 2001-09-13 2003-04-10 November Ag Molekulare Medizin Verwendung eines Proteins zur Herstellung eines Medikaments zur Stimulierung einer inflammatorischen zellulären Immunantwort
DE10302422A1 (de) * 2003-01-21 2004-07-29 Responsif Gmbh Medikament und Verwendung zur Tumortherapie
US8071545B2 (en) * 2005-03-15 2011-12-06 Lewis S. Coleman, Md, Inc. Therapies and compositions for controlling the stress mechanism and for stabilizing hemostasis in an organism
GB0911042D0 (en) 2009-06-25 2009-08-12 Istituto Superiore Di Sanito Treatment of tumorigenic cells in solid tumours

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Publication number Publication date
JP2017530130A (ja) 2017-10-12
EP3200811A1 (en) 2017-08-09
US20220160829A1 (en) 2022-05-26
AU2015327887A1 (en) 2017-04-13
CA2962255A1 (en) 2016-04-07
WO2016054574A1 (en) 2016-04-07
US11253568B2 (en) 2022-02-22
US20170202914A1 (en) 2017-07-20
EP3200811A4 (en) 2018-05-02

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Date Code Title Description
PA0105 International application

Patent event date: 20170414

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination