KR20170050390A - Composition for anti-fine dust comprising negative charged material - Google Patents

Abstract

Disclosed is a dustproof composition comprising a negatively charged material. A polymer or an inorganic matter included in the dustproof composition as an active ingredient has a similar zeta potential to dust. Accordingly, the dustproof composition can minimize that dust is attached to the skin through electrostatic power and can easily remove dust from the skin even if the dust is temporarily attached to the skin. Especially, skin penetration of fine dust is prevented, and skin irritation and heavy metal accumulation can be minimized so the dustproof composition is helpful for skin health.

Description

TECHNICAL FIELD [0001] The present invention relates to a composition for anti-dust protection comprising a negative charge material,

Disclosed herein is a novel composition for dustproofing.

If the dust accumulates in the body, the body's immune system will drop, and it can cause various diseases such as heart disease and respiratory disease. Even causing bronchial stenosis and prolonged inhalation increase the prevalence of asthma and lung disease and increase early mortality.

The skin acts as a barrier between the organism and the environment at the outermost of our body, which is in direct contact with the dust. This barrier function is often impaired when exposed directly to pollution. In particular, fine dust is 20 times smaller than pores and can easily penetrate the skin. In fact, air pollutants such as fine dusts are known to have a profound effect on skin health. In the short term, it can lead to premature aging, lack of moisture, wrinkles and wrinkles, and serious illnesses such as skin cancer, with skin irreparable in the long run losing its ability to protect the body from environmental factors .

Therefore, there is a need for studies on cosmetics to prevent the adherence of dust, which is harmful to the skin and sometimes harmful to the human body, which is harmful substance, to the skin.

Health effects of fine dusts, Korea Medical Association, Shin Dongcheon, 175-182page, 2006.2.12

In one aspect, an object of the present invention is to prevent dust from adhering to the skin.

In another aspect, an object of the present invention is to easily remove dust adhering to the skin.

In another aspect, an object of the present invention is to minimize skin penetration of fine dust.

In another aspect, an object of the present invention is to prevent or minimize skin contamination due to fine dust.

In one aspect, the present invention provides a dustproofing composition comprising a negative charge material having a zeta potential value of -2 mV or lower in an aqueous solution of pH 7 as an active ingredient, and the negative charge material is a polymer or an inorganic material.

In one aspect, the dust-proofing composition of the present invention can minimize adhesion of dust, particularly fine dust, to the skin. Specifically, since a negative charge material contained in an antidustence composition as an effective component has a zeta potential of a negative charge similar to that of a dust, it is possible to minimize adherence of dust to the skin by electrostatic force, Even if attached, dust can easily be removed from the skin. In particular, it prevents skin infiltration of fine dust, thereby minimizing skin inflammation and accumulation of heavy metals, which is beneficial for skin health.

Figure 1 shows the results of a carbon black adsorption test on artificial leather treated with a composition comprising negative charge candidate materials (1: control, 2: PMAA-sodium salt (MW = 75100) Sodium salt (MW = 18500), 4: PMAA-sodium salt (MW = 7750), 5: phospholipone 100, 6: MPC-TiO ₂ , 7: PMAA-sodium solution, phone 90 containing, 9: titanium oxide (TiO ₂ (titanium oxide)) containing, 10: PMAA-TiO ₂ contained, 11: control group, 12: zinc oxide (ZnO, (zinc oxide)) containing, 13: aluminum (Al oxide ₂ O ₃ ), and 14: chitosan-containing).
FIG. 2 shows the results of a carbon black adsorption test on artificial hair treated with a composition comprising negative charge candidate materials (blank: control, sample 1: PMAA-sodium salt (mw = 75100) Containing MPC-TiO2, Sample 5: containing PMAA-sodium, Sample 6: containing PMAA-sodium salt (mw = 18500), Sample 3: containing phospholipone 100, Sample 4: containing MPC surface treated titanium dioxide Containing titanium dioxide (PMAA-TiO2).

In the present specification, dustproof means to prevent dust from adhering to the skin or to prevent the dust temporarily adhering to the skin from being removed from the skin and penetrating into the skin. That is, when the dust-proofing composition of the present invention is applied to the skin, it is possible to minimize the adherence of dust to the skin, and even if dust adheres to the skin, it can be easily removed by physical force such as wind.

In the present specification, dust is a generic term of fine particles mixed in the air and means a suspended material having a particle diameter of usually 0.1 to 10 mm. Particularly, when the particle diameter is 10 μm or less, it is called fine dust, and when it is 0.1 μm or less, it is also called minute dust. Here, the particle size can mean the average value of the particle diameter of the fine dust particles. Dust is a material that is derived from nature, such as sand, soil, and pollen, or from industrial processes such as carbon, carbon burn, metal salts, and heavy metals. The presence of dust can be fume, mist, smoke, steam or mist. In general, the zeta potential of dust, especially fine dust, is negative.

In one aspect, the present invention is a composition for vibration damping, which comprises a negative charge material having a zeta potential value of -2 mV or lower in an aqueous solution of pH 7 as an effective component, and the negative charge material is a polymer or an inorganic material. In this specification, a negative charge substance may mean a substance having a negative zeta potential value. The zeta potential value can be measured by a conventionally known method.

The zeta potential value of the negative charge material may be -2 mV or less and may be -3 mV or less, -10 mV or less, -20 mV or less, -30 mV or less, -40 mV or less, -50 mV or less, -60 mV or less or -70 mV or less But is not limited to.

In this aspect, the negative charge material may have a zeta potential value in an aqueous solution of pH 7 of -50 mV to -10 mV. The zeta potential value is in the range of -50 mV to -10 mV, -45 mV to -10 mV, -40 mV to -10 mV, -35 mV to -10 mV, -30 mV to -10 mV, -25 mV to -10 mV, -50 mV to -40 mV, -50 mV to -20 mV, -50 mV to -25 mV, -50 mV to -30 mV, -50 mV to -35 mV, or -50 mV to -40 mV. Particularly, when the zeta potential of the polymer or the inorganic material is in the range of -45 mV to -10 mV, the fine dust-preventing effect is most excellent. Since the fine dust has a negative zeta potential, the skin adhesion may be minimized by the electrostatic repulsion force with the negative charge substance in the dustproof composition.

In this regard, the polymer may be, but is not limited to, phospholipid or poly (methacrylate).

In addition, the inorganic material may be silicon dioxide (SiO ₂ ) or titanium dioxide (TiO ₂ ), but is not limited thereto.

In addition, the phospholipid may be composed of phosphatidylglycerol, phosphatidylethanolamine, phosphatidylserine, polyethyleneglycol phospholipid, sphingomyelin, and phosphatidylcholine. But is not limited thereto.

In addition, the phosphatidylcholine may be hydrogenated phosphatidylcholine.

In one embodiment, the phosphatidylcholine is selected from the group consisting of phospholipon 50®, phospholipon 75® phospholipon 80H®, phospholipon 85G® phospholipone, 90G® (phospholipon90G®) phospholipon90H® phospholipon50® This can be a phospholipon50® or a phospholipon100®. These materials can be obtained from Sigma Aldrich.

In addition, the poly (methacrylate) may include a poly (methacrylic acid) sodium salt.

In one embodiment, the poly (methacrylic acid) sodium salt is selected from the group consisting of poly (methacrylic acid) -sodium salt (PMAA-Na Salt) (MW = 75100), poly Sodium salt (PMAA-Na salt) (MW = 18500), poly (methacrylic acid) -sodium salt (MW = 7750) or poly (methacrylic acid) Salt) (MW = 1270). These are available from Sigma Aldrich.

In addition, in the above-mentioned aspect, the inorganic material may be formed by 2-methacryloyloxy ethyl phosphorylcholine (MPC) or poly (methacrylic acid) It may be processed. This surface treatment can be carried out by reacting the surface of the inorganic material with a coupling agent and then reacting the biocompatible polymer 2-methacryloyloxyethylphosphorylcholine (MPC) or poly (methacrylic acid) But the surface treatment method is not limited thereto. For example, a known method such as the method disclosed in Korean Patent No. 2012-0065929 can be used.

In this respect, the negative charge material may be contained in an amount of 1 to 50% by weight based on the total weight of the composition. The content of the negative charge material is not limited and may be 1 to 40 wt%, 1 to 30 wt%, 1 to 20 wt%, 1 to 10 wt%, 1 to 8 wt%, 1 to 6 wt% or 1 to 4 wt% %. ≪ / RTI >

In the above aspect, the composition may be to dust the fine dust having a particle diameter of 10 mu m or less. The size of the particle size is not limited and may be 100 μm or less, 90 μm or less, 70 μm or less, 50 μm or less, 30 μm or less, 20 μm or less, 15 μm or less or 10 μm or less.

In the above aspects, the dust-proofing composition may be a cosmetic composition, and the cosmetic composition may be a cosmetic composition for make-up, particularly a powder or a powder.

As used herein, the term " cosmetic "may refer to any substance that, in addition to cosmetic functions, may have additional medical functions in addition to cosmetic functions.

Specifically, the cosmetic composition may be, for example, a basic cosmetic composition, a makeup cosmetic composition, a hair cosmetic composition, a body cosmetic composition or the like, and the formulation is not particularly limited and may be appropriately selected according to the purpose.

For example, the cosmetic composition can be formulated into a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation, But is not limited thereto. More specifically, the present invention relates to a cosmetic composition, which comprises at least one of a softening agent, a nutritional lotion, a lotion, a body lotion, a nutritional cream, a massage cream, a moisturizing cream, a hand cream, an essence, an eye cream, a cleansing cream, a cleansing foam, a cleansing water, Shampoos, rinses, body cleansers, toothpastes or mouthwashes, hair tonics, cosmetics, cosmetics, cosmetics, cosmetics, cosmetics, Gel or mousse, or a hair cosmetic composition such as a hair dye or a hair dye.

Hereinafter, the present invention will be described more specifically with reference to the following examples. However, the following embodiments are provided for illustrative purposes only in order to facilitate understanding of the present invention, and the scope and scope of the present invention are not limited thereto.

[Example 1] Analysis of zeta potential of fine dust and yellow sand standards and selection of fine dust substitute

In order to select the dust substitute material to be used in confirming the dustproof effect of the present invention, the zeta potential of the candidate group of fine dust, yellow dust, and dust substitute was analyzed. The zeta potential was measured using a Zetasizer nano instrument (Malvern). To avoid air bubbles in the Zeta cell, the zeta cell was inserted into the Zetasizer nano instrument, and the zeta potential was measured by filling the colloid or emulsion state with a syringe and closing the zeta cell with a plug.

The results are shown in Table 1 below.

division Sample Zeta Potential (mV) fine dust Fine dust (Hankuk University of Foreign Studies) -16.7 Yellow dust (Yangjae-dong) -21.2 European Standard Substance (Sigma Aldrich) -14.3 In vitro
test sample Carbon black (LC902) -18.3 Iron oxide (Mapico) -0.1 Charcoal powder -29.0

* Substances listed in parentheses are sources of each substance.

The fine dust is generally composed of 22% of organic carbon compounds, 8% of carbon element, 22% of nitrate, 15% of sulfate, 15% of soil perception component and 18% of other (National Academy of Sciences) Carbon black, which occupies about 30% (organic carbon compounds and carbon elements) and has zeta potential similar to that of fine dust, was selected as a substitute for the fine material.

[Embodiment 2] Measurement of dustproof effect

[Example 2-1] Leather experiment

The zeta potential values of the candidate materials to be used in the antivibration composition are as shown in Table 2 below.

division Sample Zeta Potential (mV) (-) charge
Candidate material
PMAA-sodium salt (PMAA-Na Salt) (MW = 75100) -34.9 PMAA-sodium salt (PMAA-Na Salt) (MW = 18500) -30.6 PMAA-sodium salt (PMAA-Na Salt) (MW = 7750) -24.6 PMAA-sodium salt (PMAA-Na Salt) (MW = 1270) -8.79 Phospholipon 100 (R) (Sigma Aldrich) -17.9 MPC Surface treated Titanium Dioxide (MPC-TiO _{2 )} -10.7 PMAA-Na solution (PMAA-Na solution) -6.7 Phospholipon 90 (Sigma Aldrich) -6.46 Phospholipon 75 (Sigma Aldrich) -6.21 PMAA surface treated titanium dioxide (PMAA-TiO ₂ ) -2.65 (+) charge
Candidate material
Zinc oxide (ZnO) 21 Aluminum oxide 29 Chitosan 4.9

(1: control, 2: PMAA-sodium salt (MW = 75100) containing 3: PMAA 5: containing phospholipone 100, 6: containing MPC-TiO ₂ , 7: containing PMAA-sodium solution, 8: containing sodium salt (MW = 18500), 4: containing PMAA-sodium salt Poly phone 90 containing, 9: titanium oxide (TiO ₂ (titanium oxide)) containing, 10: PMAA-containing TiO _2, 11: control group, 12: chitosan-containing): ZnO-containing, 13: an aluminum-containing, oxide 14. PMAA-Na salt (MW = 75100), PMAA-Na salt (MW = 18500) and PMAA-Na salt (PMAA-Na salt) MW = 7750), PMAA-Na salt (MW = 1270), PMAA-Na solution (434507 ALDRICH), Phospholipon 100®, Phospholipone 90 (Phospholipon 90®) and Phospholipon 75® were obtained from Sigma Aldrich. In MPC-TiO ₂ and PMAA-TiO ₂ , a coupling agent is reacted with a surface of TiO ₂ having an -OH functional group, and 0.1 to 10 wt% of each of MPC polymer and PMAA polymer is coated (more specifically, 3 wt% , Followed by filtration and pulverization.

Each of these compositions was evenly applied to each of the artificial leathers and was dried for 10 minutes and then placed in a convection box containing 3.125 g of carbon black (which is 500,000 times the level of the fine dust alarm of Korean vapor iron) After sufficiently convecting the air in the convection box with the convection circulation device, the carbon black remaining on the artificial leather was visually confirmed. As a result, it was found that the carbon black was least detected in the leather to which the cosmetic composition containing the PMAA-sodium salt (mw = 75100) having the largest absolute negative charge of zeta potential was applied, and PMAA-sodium salt (mw = 75100), PMAA Sodium salt (mw = 18500), PMAA-sodium salt (mw = 7750), PMAA-sodium salt solution and Phospholipon 100® were found to have a dust-proofing effect.

[Example 2-2] Artificial hair test

(Blank: control group, sample 1: PMAA-sodium salt (mw = 75100), sample 2: PMAA- (MPC-TiO2), Sample 5 contains PMAA-sodium, Sample 6 contains PMAA-treated sodium dioxide (mw = 18500), Sample 3 contains phospholipone 100, Sample 4 contains MPC- Titanium (PMAA-TiO2). The hair mists were sprayed on each of the same hair samples, treated with carbon black in a convection box under the same conditions as in Example 2-1, and the mass of the hair was measured. The larger the absolute value of the zeta potential negative charge, the smaller the increase in the mass of hair, and the larger the magnitude of the zeta potential negative charge, the better the dust protection effect.

Hereinafter, a formulation example of the composition according to the present invention will be described. However, the pharmaceutical composition and the cosmetic composition can be applied to various formulations, which are not intended to limit the present invention but merely to illustrate the present invention.

Flexible longevity (skin lotion) Compounding ingredient weight% Purified water Balance Negative charge substance 10.0 Ethyleniminametetraacetic acid 0.02 glycerin 5.0 Butylene glycol 3.0 Pigment / PPGI-17/6 Copolymer (Copolymer) 3.0 ethanol 5.0 Polyoxyethylene hydrogencarbonate
Castor oil 0.4 Methyl paraben 0.1 Fragrance 0.1 Preservative, coloring, fragrance Suitable amount

Flexible longevity (milk lotion) Compounding ingredient content Purified water Balance Negative charge substance 10.0 Wax 4.0 Polysorbate 60 1.5 Sorbitan sesquioleate 1.5 Liquid paraffin 0.5 Caprylic / capric triglyceride 5.0 glycerin 3.0 Butylene glycol 3.0 Propylene glycol 3.0 Carboxyvinyl polymer 0.1 Triethanolamine 0.2 Preservative, coloring, fragrance Suitable amount

Powder or fact cosmetic Compounding ingredient weight% Negative charge substance 10.0 Nylon Powder 5.0 Modified starch 3.0 Titanium dioxide 3.0 Mica 25.0 Squalene 0.5 Dimethicone 0.8 Preservative, coloring, fragrance Suitable amount Silicone-treated talc to 100

Hair Mist Compounding ingredient content Purified water TO 100 Negative charge substance 10 glycerin 5.0 Butylene glycol 5.0 Phenoxyethanol 0.5 PEG / PPG block copolymer 1.5 Sodium chloride 0.3 ethanol 3.0 Dimethicone 10.0

The hair mists were prepared using homogenizer without emulsification process.

Nourishing cream Compounding ingredient content Purified water Balance Negative charge substance 5.0 Wax 10.0 Polysorbate 60 1.5 PEG60 hardened castor oil 2.0 Sorbitan sesquioleate 0.5 Liquid paraffin 10.0 Squalane 5.0 Caprylic / capric triglyceride 5.0 glycerin 5.0 Butylene glycol 3.0 Propylene glycol 3.0 Triethanolamine 0.2 Preservative, coloring, fragrance Suitable amount

Claims (14)

a negative charge substance having a zeta potential value of -2 mV or lower in an aqueous solution of pH 7 as an active ingredient,
Wherein the negative charge material is a polymer or an inorganic material. The method according to claim 1,
The negative charge material,
wherein the zeta potential value in an aqueous solution of pH 7 is not more than -10 mV. 3. The method of claim 2,
The negative charge material,
wherein the zeta potential value in an aqueous solution of pH 7 is from -50 mV to -10 mV. The method according to claim 1,
The polymer may be,
Wherein the composition is a phospholipid or poly (methacrylate). The method according to claim 1,
The above-
Silicon dioxide (SiO ₂₎ or titanium dioxide (TiO ₂₎ in the composition for anti-vibration. 5. The method of claim 4,
The phospholipid,
Wherein the composition is selected from the group consisting of phosphatidylglycerol, phosphatidylethanolamine, phosphatidylserine, polyethyleneglycol phospholipid, sphingomyelin and phosphatidylcholine. Composition. The method according to claim 6,
The phosphatidylcholine,
A composition for preventing dust, comprising hydrogenated phophatidylcholine. 5. The method of claim 4,
Wherein the poly (methacrylate) comprises a poly (methacrylic acid) sodium salt. The method according to claim 1,
The above-
Wherein the composition is surface-treated with 2-methacryloyloxy ethyl phosphorylcholine (MPC) or poly (methacrylic acid). The method according to claim 1,
Negative charge substances,
1 to 50% by weight, based on the total weight of the composition. The method according to claim 1,
The composition may comprise,
Wherein the fine dust having a particle diameter of 10 mu m or less is dustproofed. 12. The method according to any one of claims 1 to 11,
Wherein the composition for vibration damping is a cosmetic composition. 13. The method of claim 12,
The cosmetic composition is a makeup composition. 14. The method of claim 13,
The makeup composition is a powder or a cosmetic composition.

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