KR20170033436A - 다낭성 신장병의 바이오마커 및 그의 용도 - Google Patents

다낭성 신장병의 바이오마커 및 그의 용도 Download PDF

Info

Publication number
KR20170033436A
KR20170033436A KR1020177005740A KR20177005740A KR20170033436A KR 20170033436 A KR20170033436 A KR 20170033436A KR 1020177005740 A KR1020177005740 A KR 1020177005740A KR 20177005740 A KR20177005740 A KR 20177005740A KR 20170033436 A KR20170033436 A KR 20170033436A
Authority
KR
South Korea
Prior art keywords
pkd
patient
cyclin
level
leu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020177005740A
Other languages
English (en)
Korean (ko)
Inventor
옥사나 베스크로브나야
니콜라이 부카노브
사라 모레노
Original Assignee
젠자임 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 젠자임 코포레이션 filed Critical 젠자임 코포레이션
Publication of KR20170033436A publication Critical patent/KR20170033436A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/492Determining multiple analytes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
KR1020177005740A 2014-08-04 2015-08-03 다낭성 신장병의 바이오마커 및 그의 용도 Withdrawn KR20170033436A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462033031P 2014-08-04 2014-08-04
US62/033,031 2014-08-04
PCT/US2015/043497 WO2016022500A2 (en) 2014-08-04 2015-08-03 Biomarkers of polycystic kidney disease and uses thereof

Publications (1)

Publication Number Publication Date
KR20170033436A true KR20170033436A (ko) 2017-03-24

Family

ID=54035292

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177005740A Withdrawn KR20170033436A (ko) 2014-08-04 2015-08-03 다낭성 신장병의 바이오마커 및 그의 용도

Country Status (12)

Country Link
US (1) US10871495B2 (https=)
EP (1) EP3177932B1 (https=)
JP (2) JP6730252B2 (https=)
KR (1) KR20170033436A (https=)
CN (1) CN106716136B (https=)
AU (1) AU2015301278A1 (https=)
BR (1) BR112017002003A2 (https=)
CO (1) CO2017001596A2 (https=)
MX (1) MX2017001648A (https=)
RU (1) RU2017106891A (https=)
SG (1) SG11201700290SA (https=)
WO (1) WO2016022500A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210063203A (ko) * 2019-11-22 2021-06-01 서울대학교산학협력단 Opn 검출용 제제를 포함하는, 다낭신의 진단용 조성물 및 이의 이용

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018006250A (es) 2015-11-18 2018-09-05 Genzyme Corp Biomarcador de enfermedad poliquistica renal y usos del mismo.
GB201719520D0 (en) * 2017-11-24 2018-01-10 Univ College Cardiff Consultants Ltd Neuroprotectvie peptide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60039601D1 (de) 1999-05-24 2008-09-04 Avi Biopharma Inc Antisense gegen c-myc zur behandlung von polyzystischer nierenkrankheit
WO2006012394A1 (en) 2004-07-21 2006-02-02 Tulane University Health Sciences Center Treatment of renal dysfunction and multiple myeloma using pacap compounds
EP1808694A1 (en) 2006-01-17 2007-07-18 Universitätsklinikum Freiburg Method for diagnosing polycystic kidney disease
US20120077263A1 (en) * 2009-06-05 2012-03-29 Mayo Foundation For Medical Education And Research Methods and materials for isolating exosomes
CN102018702B (zh) * 2009-09-16 2012-07-18 北京大学 银杏内酯b的一种用途
WO2012042061A1 (en) * 2010-10-01 2012-04-05 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the progression and treating a chronic kidney disease in a patient
US20130276513A1 (en) * 2010-10-14 2013-10-24 The Regents Of The University Of California Methods for diagnosing and assessing kidney disease
WO2014006093A1 (en) 2012-07-03 2014-01-09 Boletta Alessandra Compounds for use in polycystic kidney disease
MA37975B2 (fr) 2012-09-11 2021-03-31 Genzyme Corp Inhibiteurs de synthase de glucosylcéramide

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210063203A (ko) * 2019-11-22 2021-06-01 서울대학교산학협력단 Opn 검출용 제제를 포함하는, 다낭신의 진단용 조성물 및 이의 이용

Also Published As

Publication number Publication date
CO2017001596A2 (es) 2017-05-19
AU2015301278A1 (en) 2017-02-09
RU2017106891A (ru) 2018-09-06
SG11201700290SA (en) 2017-02-27
US10871495B2 (en) 2020-12-22
JP7005695B2 (ja) 2022-02-04
CN106716136A (zh) 2017-05-24
WO2016022500A3 (en) 2016-04-07
JP2017525955A (ja) 2017-09-07
JP6730252B2 (ja) 2020-07-29
MX2017001648A (es) 2017-04-27
JP2020170013A (ja) 2020-10-15
WO2016022500A2 (en) 2016-02-11
CN106716136B (zh) 2020-06-23
RU2017106891A3 (https=) 2019-03-14
EP3177932B1 (en) 2021-07-14
US20170227551A1 (en) 2017-08-10
BR112017002003A2 (pt) 2017-12-12
EP3177932A2 (en) 2017-06-14

Similar Documents

Publication Publication Date Title
US12150938B2 (en) Biomarker of polycystic kidney disease and uses thereof
Wang et al. Mesenchymal stem cells ameliorate lipid metabolism through reducing mitochondrial damage of hepatocytes in the treatment of post-hepatectomy liver failure
JP7005695B2 (ja) 多発性嚢胞腎のバイオマーカーおよびその使用
RU2720988C2 (ru) ИНГИБИТОРЫ GATA-3 ДЛЯ ПРИМЕНЕНИЯ В ЛЕЧЕНИИ Th2-ИНДУЦИРОВАННОЙ АСТМЫ
García-Marchena et al. Psychiatric comorbidity and plasma levels of 2-acyl-glycerols in outpatient treatment alcohol users. Analysis of gender differences
JP5680744B2 (ja) 併用療法及び治療耐性評価方法
Spencer et al. Neuropathological profile of long‐duration amyotrophic lateral sclerosis in military veterans
Cains et al. Addressing a folate imbalance in fetal cerebrospinal fluid can decrease the incidence of congenital hydrocephalus
Pellegrini et al. Lack of p62 impairs glycogen aggregation and exacerbates pathology in a mouse model of myoclonic epilepsy of Lafora
Wang et al. Lymphocyte α-kinase is a gout-susceptible gene involved in monosodium urate monohydrate-induced inflammatory responses
Chen et al. Pip5k1γ promotes anabolism of nucleus pulposus cells and intervertebral disc homeostasis by activating CaMKII‐Ampk pathway in aged mice
JP2019502902A5 (https=)
TW202112368A (zh) 用於治療有關dux4表現之疾病的抑制劑組合
Park et al. Regulation of phosphorylation of glycogen synthase kinase 3α and the correlation with sperm motility in human
JP2017525955A5 (https=)
US20250170129A1 (en) Senotherapeutic agents and alpha-klotho polypeptides
Yongman et al. Renoprotective effect of benazepril on diabetic nephropathy mediated by P42/44MAPK
JP2024541901A (ja) レビー小体型認知症を有する患者の選択的集団の処置
WO2022122889A1 (en) Methods and compositions for detecting the activation of mtor pathway
CN119492868A (zh) 一种系膜增生性肾小球肾炎的潜在生物标志物及其应用
Harmon Serotonin Receptor 2-Induced Mitochondrial Biogenesis as a Therapeutic Strategy for the Treatment of Multiple Pathologies
HK1230980B (en) Gata-3 inhibitors for use in the treatment of th2-driven asthma
WO2014168508A1 (ru) Способ диагностики нефротоксичности циклосоприна а у детей с нефротическим синдромом

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20170228

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination