KR20170005121A - 폼일 펩타이드 수용체 조절제로서의 이미다졸 유도체 - Google Patents
폼일 펩타이드 수용체 조절제로서의 이미다졸 유도체 Download PDFInfo
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- KR20170005121A KR20170005121A KR1020167035670A KR20167035670A KR20170005121A KR 20170005121 A KR20170005121 A KR 20170005121A KR 1020167035670 A KR1020167035670 A KR 1020167035670A KR 20167035670 A KR20167035670 A KR 20167035670A KR 20170005121 A KR20170005121 A KR 20170005121A
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Classifications
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- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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Landscapes
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- Engineering & Computer Science (AREA)
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Applications Claiming Priority (3)
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| PCT/US2015/032069 WO2015179707A1 (en) | 2014-05-21 | 2015-05-21 | Imidazole derivatives as formyl peptide receptor modulators |
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| US12478503B2 (en) | 2009-05-18 | 2025-11-25 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| UA115043C2 (uk) | 2011-10-26 | 2017-09-11 | Аллерган, Інк. | Амідні похідні n-карбамідзаміщених амінокислот як модулятори формілпептидного рецептора 1 (fprl-1) |
| RU2696487C2 (ru) * | 2013-03-06 | 2019-08-02 | Аллерган, Инк. | Применение агонистов формилпептидного рецептора 2 для лечения дерматологических заболеваний |
| AU2014352922B2 (en) | 2013-11-21 | 2018-06-07 | Allergan, Inc. | Phenylcarbamate derivatives as formyl peptide receptor modulators |
| CA2948876A1 (en) | 2014-05-21 | 2015-11-26 | Allergan, Inc. | Imidazole derivatives as formyl peptide receptor modulators |
| AU2017249047B2 (en) * | 2016-04-12 | 2021-08-05 | Allergan, Inc. | Phenyl urea derivatives as N-formyl peptide receptor modulators |
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| FR2533210A1 (fr) | 1982-09-17 | 1984-03-23 | Lyon I Universite Claude | Edulcorants de synthese |
| WO2005047899A2 (en) | 2003-11-07 | 2005-05-26 | Acadia Pharmaceuticals Inc. | Use of the lipoxin receptor, fprl1, as a tool for identifying compounds effective in the treatment of pain and inflammation |
| PL1723128T3 (pl) | 2004-01-06 | 2013-04-30 | Novo Nordisk As | Pochodne heteroarylowe mocznika oraz ich zastosowanie jako aktywatory glukokinazy |
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| CA2660758A1 (en) * | 2006-08-24 | 2008-02-27 | Astrazeneca Ab | Morpholino pyrimidine derivatives useful in the treatment of proliferative disorders |
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| BRPI0814818A2 (pt) * | 2007-07-09 | 2019-09-10 | Astrazeneca Ab | composto, uso de um composto, métodos para produzir um efeito anti-proliferativo e um efeito inibitório de mtor quinase em uma animal de sangue quente, método para tratar doenças, e, composição farmacêutica |
| CN101998680B (zh) * | 2009-08-24 | 2016-01-13 | 中兴通讯股份有限公司 | 帧序列号的发送方法及节点b和服务无线网络控制器 |
| AU2011336973A1 (en) | 2010-12-03 | 2013-07-11 | Allergan, Inc. | Pharmaceutical compositions comprising 3,4- dihydroisoquinolin-2(1 H)-yl-3-phenylurea derivatives having formyl peptide receptor like-1 (FPRL-1) agonist or antagonist activity |
| CA2827005A1 (en) | 2011-02-11 | 2012-08-16 | Allergan, Inc. | Novel 1-(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)urea derivatives as n-formyl peptide receptor like-1 (fprl-1) receptor modulators |
| EP2731931A1 (en) | 2011-07-11 | 2014-05-21 | Allergan, Inc. | Polycyclic pyrrolidine-2,5-dione derivatives as -formyl peptide receptor like-1 (fprl-1) receptor modulators |
| UA115043C2 (uk) * | 2011-10-26 | 2017-09-11 | Аллерган, Інк. | Амідні похідні n-карбамідзаміщених амінокислот як модулятори формілпептидного рецептора 1 (fprl-1) |
| US8541577B2 (en) | 2011-11-10 | 2013-09-24 | Allergan, Inc. | Aryl urea derivatives as N-formyl peptide receptors like-1 (FPRL-1) receptor modulators |
| US8492556B2 (en) * | 2011-11-10 | 2013-07-23 | Allergan, Inc. | 2,5-Dioxoimidazolidin-1-yl-3-phenylurea derivatives as formyl peptide receptor like-1 (FPRL-1) receptor modulators |
| US8729096B2 (en) | 2012-02-16 | 2014-05-20 | Allergan, Inc. | Imidazolidine-2,4-dione derivatives as N-formyl peptide receptor 2 modulators |
| KR20140145203A (ko) | 2012-04-16 | 2014-12-22 | 알러간, 인코포레이티드 | 포르밀 펩타이드 수용체 2 조절물질로서 (2-우레이도아세트아미도)알킬 유도체 |
| RU2696487C2 (ru) | 2013-03-06 | 2019-08-02 | Аллерган, Инк. | Применение агонистов формилпептидного рецептора 2 для лечения дерматологических заболеваний |
| CN105007909B (zh) | 2013-03-06 | 2019-06-28 | 阿勒根公司 | 用于治疗眼部炎性疾病的甲酰基肽受体2激动剂的用途 |
| CN105377814B (zh) | 2013-07-16 | 2018-04-03 | 阿勒根公司 | 作为甲酰基肽受体调节剂的n‑脲取代的氨基酸的衍生物 |
| AU2014352922B2 (en) | 2013-11-21 | 2018-06-07 | Allergan, Inc. | Phenylcarbamate derivatives as formyl peptide receptor modulators |
| WO2015116566A1 (en) | 2014-01-29 | 2015-08-06 | Allergan, Inc. | 2,5-dioxoimidazolidin-1-yl-3-urea derivatives as formyl peptide modulators |
| US9604934B2 (en) | 2014-01-29 | 2017-03-28 | Allergan, Inc. | Urea hydantoin derivatives as formyl peptide modulators |
| US9663457B2 (en) | 2014-04-09 | 2017-05-30 | Allergan, Inc. | Carbamoyl hydrazine derivatives as formyl peptide modulators |
| CA2948876A1 (en) | 2014-05-21 | 2015-11-26 | Allergan, Inc. | Imidazole derivatives as formyl peptide receptor modulators |
| WO2017172761A1 (en) | 2016-03-28 | 2017-10-05 | Allergan, Inc. | Phenyl urea derivatives as n-formyl peptide receptor modulators |
| AU2017249047B2 (en) | 2016-04-12 | 2021-08-05 | Allergan, Inc. | Phenyl urea derivatives as N-formyl peptide receptor modulators |
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2015
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- 2015-05-21 WO PCT/US2015/032069 patent/WO2015179707A1/en not_active Ceased
- 2015-05-21 EP EP15726498.7A patent/EP3145916B1/en active Active
- 2015-05-21 US US15/312,367 patent/US10301269B2/en active Active
- 2015-05-21 BR BR112016027133A patent/BR112016027133A8/pt not_active Application Discontinuation
- 2015-05-21 DK DK15726498.7T patent/DK3145916T3/da active
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- 2015-05-21 AU AU2015264021A patent/AU2015264021B2/en not_active Ceased
- 2015-05-21 JP JP2016568605A patent/JP6660889B2/ja not_active Expired - Fee Related
- 2015-05-21 KR KR1020167035670A patent/KR20170005121A/ko not_active Ceased
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| DK3145916T3 (da) | 2020-05-11 |
| WO2015179707A1 (en) | 2015-11-26 |
| AU2015264021B2 (en) | 2020-02-27 |
| BR112016027133A2 (pt) | 2017-08-15 |
| US20200115346A1 (en) | 2020-04-16 |
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| JP2017520528A (ja) | 2017-07-27 |
| RU2748652C2 (ru) | 2021-05-28 |
| AU2020203420A1 (en) | 2020-06-11 |
| US20170096401A1 (en) | 2017-04-06 |
| JP6660889B2 (ja) | 2020-03-11 |
| BR112016027133A8 (pt) | 2021-06-29 |
| US10301269B2 (en) | 2019-05-28 |
| EP3145916A1 (en) | 2017-03-29 |
| RU2016145596A (ru) | 2018-06-21 |
| CA2948876A1 (en) | 2015-11-26 |
| EP3145916B1 (en) | 2020-02-12 |
| AU2020203420B2 (en) | 2021-12-16 |
| US10800744B2 (en) | 2020-10-13 |
| ES2788700T3 (es) | 2020-10-22 |
| CN106458921B (zh) | 2020-03-24 |
| CN106458921A (zh) | 2017-02-22 |
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