KR20170002550A - 티에노트리아졸로디아제핀 화합물을 사용한 내성 비호지킨 림프종, 수아세포종, 및/또는 alk+ 비소세포 폐암의 치료 방법 - Google Patents
티에노트리아졸로디아제핀 화합물을 사용한 내성 비호지킨 림프종, 수아세포종, 및/또는 alk+ 비소세포 폐암의 치료 방법 Download PDFInfo
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- KR20170002550A KR20170002550A KR1020167033941A KR20167033941A KR20170002550A KR 20170002550 A KR20170002550 A KR 20170002550A KR 1020167033941 A KR1020167033941 A KR 1020167033941A KR 20167033941 A KR20167033941 A KR 20167033941A KR 20170002550 A KR20170002550 A KR 20170002550A
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- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
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- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
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| US201461987813P | 2014-05-02 | 2014-05-02 | |
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| US201461990469P | 2014-05-08 | 2014-05-08 | |
| US61/990,469 | 2014-05-08 | ||
| US61/990,459 | 2014-05-08 | ||
| PCT/US2015/028798 WO2015168555A1 (en) | 2014-05-02 | 2015-05-01 | Method of treating resistant non-hodgkin lymphoma, medulloblastoma, and/or alk+non-small cell lung cancer using thienotriazolodiazepine compounds |
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| KR20170002550A true KR20170002550A (ko) | 2017-01-06 |
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| US (1) | US20170095484A1 (https=) |
| EP (1) | EP3137086A4 (https=) |
| JP (1) | JP2017514907A (https=) |
| KR (1) | KR20170002550A (https=) |
| CN (1) | CN106687117A (https=) |
| AU (1) | AU2015252940A1 (https=) |
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| MX (1) | MX2016014299A (https=) |
| RU (1) | RU2016146102A (https=) |
| WO (1) | WO2015168555A1 (https=) |
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| MX366703B (es) | 2013-03-15 | 2019-07-22 | Incyte Holdings Corp | Heterociclos tricíclicos como inhibidores de la proteína bet. |
| AR096837A1 (es) | 2013-07-08 | 2016-02-03 | Incyte Corp | Heterociclos tricíclicos como inhibidores de proteínas bet |
| WO2015081189A1 (en) | 2013-11-26 | 2015-06-04 | Incyte Corporation | Bicyclic heterocycles as bet protein inhibitors |
| US9399640B2 (en) | 2013-11-26 | 2016-07-26 | Incyte Corporation | Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors |
| WO2015095492A1 (en) | 2013-12-19 | 2015-06-25 | Incyte Corporation | Tricyclic heterocycles as bet protein inhibitors |
| EA034972B1 (ru) | 2014-04-23 | 2020-04-13 | Инсайт Корпорейшн | 1h-пирроло[2,3-c]пиридин-7(6h)-оны в качестве ингибиторов белков bet |
| US9968620B2 (en) * | 2014-08-19 | 2018-05-15 | Oncoethix Gmbh | Methods of treating lymphoma using thienotriazolodiazepine compounds |
| US9527864B2 (en) | 2014-09-15 | 2016-12-27 | Incyte Corporation | Tricyclic heterocycles as BET protein inhibitors |
| US10683305B2 (en) | 2015-04-27 | 2020-06-16 | Concert Pharmaceuticals, Inc. | Deuterated OTX-015 |
| TW201722966A (zh) | 2015-10-29 | 2017-07-01 | 英塞特公司 | Bet蛋白質抑制劑之非晶固體形式 |
| KR102643344B1 (ko) | 2016-06-20 | 2024-03-07 | 인사이트 코포레이션 | Bet 저해제의 결정질 고체 형태 |
| CN110996913A (zh) * | 2017-06-30 | 2020-04-10 | 欧恩科斯欧公司 | 新的贝利司他口服制剂 |
| US11833155B2 (en) | 2020-06-03 | 2023-12-05 | Incyte Corporation | Combination therapy for treatment of myeloproliferative neoplasms |
| AU2022243527A1 (en) * | 2021-03-26 | 2023-11-09 | Impact Therapeutics (Shanghai) , Inc | Oral capsule of parp inhibitor and preparation method thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001095912A1 (fr) * | 2000-06-16 | 2001-12-20 | Mitsubishi Pharma Corporation | Compositions permettant de reguler la plage et/ou la vitesse de liberation du ph |
| WO2009084693A1 (ja) * | 2007-12-28 | 2009-07-09 | Mitsubishi Tanabe Pharma Corporation | 抗癌剤 |
| PL2902030T3 (pl) * | 2010-05-14 | 2017-07-31 | Dana-Farber Cancer Institute, Inc. | Związki tienotriazolodiazepinowe do leczenia nowotworu |
| MX2014015986A (es) * | 2012-06-25 | 2016-02-11 | Oncoethix Gmbh | Metodo para tratar linfoma utilizando compuestos de tienotriazolodiazepina. |
| CN104968334B (zh) * | 2012-09-28 | 2018-09-14 | 翁科埃斯克斯有限公司 | 包含噻吩并三唑并二氮杂卓化合物的药物制剂 |
| WO2015018522A1 (en) * | 2013-08-06 | 2015-02-12 | Oncoethix Sa | Bet-bromodomain inhibitor shows synergism with several anti-cancer agents in pre-clinical models of diffuse large b-cell lymphoma (dlbcl) |
| WO2015018520A1 (en) * | 2013-08-06 | 2015-02-12 | Oncoethix Sa | A bet-brd inhibitor represents a novel agent for alk positive anaplastic large cell lymphoma |
| CN105960239A (zh) * | 2013-11-27 | 2016-09-21 | 翁科埃斯克斯有限公司 | 利用含有噻吩并三唑并二氮杂*化合物的药物制剂治疗白血病的方法 |
| WO2015078928A1 (en) * | 2013-11-27 | 2015-06-04 | Oncoethix Sa | Method of treating non-small-cell lung cancer using pharmaceutical formulation containing thienotriazolodiazepine compounds |
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- 2015-05-01 AU AU2015252940A patent/AU2015252940A1/en not_active Abandoned
- 2015-05-01 KR KR1020167033941A patent/KR20170002550A/ko not_active Withdrawn
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- 2015-05-01 RU RU2016146102A patent/RU2016146102A/ru not_active Application Discontinuation
- 2015-05-01 CA CA2947593A patent/CA2947593A1/en not_active Abandoned
- 2015-05-01 CN CN201580036829.XA patent/CN106687117A/zh active Pending
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| EP3137086A4 (en) | 2017-12-27 |
| EP3137086A1 (en) | 2017-03-08 |
| MX2016014299A (es) | 2017-01-27 |
| JP2017514907A (ja) | 2017-06-08 |
| CN106687117A (zh) | 2017-05-17 |
| CA2947593A1 (en) | 2015-11-05 |
| RU2016146102A (ru) | 2018-06-05 |
| AU2015252940A1 (en) | 2016-11-17 |
| US20170095484A1 (en) | 2017-04-06 |
| RU2016146102A3 (https=) | 2018-12-17 |
| WO2015168555A1 (en) | 2015-11-05 |
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