KR20160090390A - 혈액암의 치료방법 및 바이오마커를 사용한 레날리도마이드에 대한 임상적 민감도의 예측방법 - Google Patents

혈액암의 치료방법 및 바이오마커를 사용한 레날리도마이드에 대한 임상적 민감도의 예측방법 Download PDF

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KR20160090390A
KR20160090390A KR1020167017539A KR20167017539A KR20160090390A KR 20160090390 A KR20160090390 A KR 20160090390A KR 1020167017539 A KR1020167017539 A KR 1020167017539A KR 20167017539 A KR20167017539 A KR 20167017539A KR 20160090390 A KR20160090390 A KR 20160090390A
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dlbcl
biological sample
tumor sample
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매튜 윌리엄 버넬 트로터
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셀진 코포레이션
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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    • G01N33/57557—Immunoassay; Biospecific binding assay; Materials therefor for cancer of other specific parts of the body, e.g. brain
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020167017539A 2013-12-06 2014-12-05 혈액암의 치료방법 및 바이오마커를 사용한 레날리도마이드에 대한 임상적 민감도의 예측방법 Withdrawn KR20160090390A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361913046P 2013-12-06 2013-12-06
US61/913,046 2013-12-06
PCT/US2014/068767 WO2015085160A2 (en) 2013-12-06 2014-12-05 Methods for treating hematological cancers and the use of biomarkers as a predictor of clinical sensitivity to immunodulatory therapies

Publications (1)

Publication Number Publication Date
KR20160090390A true KR20160090390A (ko) 2016-07-29

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KR1020167017539A Withdrawn KR20160090390A (ko) 2013-12-06 2014-12-05 혈액암의 치료방법 및 바이오마커를 사용한 레날리도마이드에 대한 임상적 민감도의 예측방법

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Country Link
US (1) US20160312292A1 (enExample)
EP (1) EP3077547A4 (enExample)
JP (1) JP2017503481A (enExample)
KR (1) KR20160090390A (enExample)
AU (1) AU2014360316A1 (enExample)
BR (1) BR112016012792A2 (enExample)
CA (1) CA2932266A1 (enExample)
EA (1) EA201691143A1 (enExample)
IL (1) IL245936A0 (enExample)
MX (1) MX2016007179A (enExample)
PH (1) PH12016501023A1 (enExample)
WO (1) WO2015085160A2 (enExample)

Families Citing this family (11)

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Publication number Priority date Publication date Assignee Title
WO2015077058A2 (en) 2013-11-08 2015-05-28 The Broad Institute, Inc. Compositions and methods for selecting a treatment for b-cell neoplasias
BR112016012795A2 (pt) 2013-12-06 2017-08-08 Celgene Corp Métodos para a determinação da eficácia do fármaco para o tratamento de linfoma difuso de grandes células b, mieloma múltiplo e cânceres mieloides
WO2016060557A1 (en) * 2014-10-17 2016-04-21 Stichting Maastricht Radiation Oncology "Maastro-Clinic" Image analysis method supporting illness development prediction for a neoplasm in a human or animal body
WO2016196580A1 (en) 2015-06-02 2016-12-08 Celgene Corporation Methods for determining drug efficacy for treatment of cancer using ratios of cereblon associated proteins
EP3347717A4 (en) 2015-09-11 2019-06-05 The Brigham and Women's Hospital, Inc. PROCESS FOR CHARACTERIZING THE RESISTANCE TO CEREBLON MODULATORS
CA2999179A1 (en) * 2015-09-25 2017-03-30 Celgene Corporation Methods for treating diffuse large b-cell lymphoma and the use of biomarkers as a predictor of responsiveness to drugs
WO2017120446A1 (en) 2016-01-08 2017-07-13 Celgene Corporation Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies
US20200270703A1 (en) * 2017-09-29 2020-08-27 Kyushu University, National University Corporation Method and kit for predicting therapeutic effectiveness of chemotherapy for diffuse large b-cell lymphoma patients
MX2022004688A (es) * 2019-10-21 2022-05-10 Celgene Corp Métodos para tratar un cáncer hematológico y uso de biomarcadores compañeros para 2-(2,6-dioxopiperidin-3-il)-4-((2-fluoro-4-((3-mor folinoazetidin-1-il)metil)bencil)amino)isoindolin-1,3-diona.
WO2024258819A1 (en) * 2023-06-15 2024-12-19 The Broad Institute, Inc. Neoplastic cytotoxicity induced by glycosylation
FR3158744A1 (fr) * 2024-01-30 2025-08-01 Universite Grenoble Alpes Biomarqueurs et outil pronostique pour les patients atteint de lymphomes b diffus a grandes cellules

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7964354B2 (en) * 2007-12-20 2011-06-21 Celgene Corporation Use of micro-RNA as a biomarker of immunomodulatory drug activity
EP2544687A1 (en) * 2010-03-12 2013-01-16 Celgene Corporation Methods for the treatment of non-hodgkin's lymphomas using lenalidomide, and gene and protein biomarkers as a predictor
MX353482B (es) * 2011-04-29 2018-01-16 Celgene Corp Metodos para el tratamiento del cancer y enfermedades inflamatorias utilizando cereblon como predictor.

Also Published As

Publication number Publication date
WO2015085160A3 (en) 2015-07-30
WO2015085160A2 (en) 2015-06-11
BR112016012792A2 (pt) 2017-08-08
US20160312292A1 (en) 2016-10-27
AU2014360316A1 (en) 2016-06-16
EP3077547A2 (en) 2016-10-12
EP3077547A4 (en) 2017-11-08
PH12016501023A1 (en) 2016-07-04
MX2016007179A (es) 2016-09-08
IL245936A0 (en) 2016-07-31
EA201691143A1 (ru) 2016-11-30
CA2932266A1 (en) 2015-06-11
JP2017503481A (ja) 2017-02-02

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Patent event date: 20160630

Patent event code: PA01051R01D

Comment text: International Patent Application

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