KR20150076266A - 급성 조증 치료용 카르바모일-시클로헥산 - Google Patents
급성 조증 치료용 카르바모일-시클로헥산 Download PDFInfo
- Publication number
- KR20150076266A KR20150076266A KR1020157016650A KR20157016650A KR20150076266A KR 20150076266 A KR20150076266 A KR 20150076266A KR 1020157016650 A KR1020157016650 A KR 1020157016650A KR 20157016650 A KR20157016650 A KR 20157016650A KR 20150076266 A KR20150076266 A KR 20150076266A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- dichlorophenyl
- piperazin
- patient
- dimethylcarbamoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUP0700370 | 2007-05-24 | ||
| HU0700370A HUP0700370A2 (en) | 2007-05-24 | 2007-05-24 | Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania |
| PCT/HU2008/000052 WO2008142463A2 (en) | 2007-05-24 | 2008-05-19 | Carbamoyl-cyclohexanes for treating acute mania |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097024073A Division KR20100022956A (ko) | 2007-05-24 | 2008-05-19 | 급성 조증 치료용 카르바모일-시클로헥산 |
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| Publication Number | Publication Date |
|---|---|
| KR20150076266A true KR20150076266A (ko) | 2015-07-06 |
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|---|---|
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| EP (1) | EP2164572B2 (enExample) |
| JP (1) | JP2010527985A (enExample) |
| KR (1) | KR20150076266A (enExample) |
| CN (2) | CN101678212A (enExample) |
| AU (1) | AU2008252621B2 (enExample) |
| CA (1) | CA2687528C (enExample) |
| CY (1) | CY1113566T1 (enExample) |
| DK (1) | DK2164572T4 (enExample) |
| EA (1) | EA021936B1 (enExample) |
| ES (1) | ES2397962T5 (enExample) |
| GE (1) | GEP20135731B (enExample) |
| HR (1) | HRP20130092T4 (enExample) |
| HU (1) | HUP0700370A2 (enExample) |
| IL (1) | IL202048A (enExample) |
| MX (1) | MX2009012752A (enExample) |
| MY (1) | MY148955A (enExample) |
| NZ (1) | NZ582284A (enExample) |
| PL (1) | PL2164572T5 (enExample) |
| PT (1) | PT2164572E (enExample) |
| RS (1) | RS52613B2 (enExample) |
| SI (1) | SI2164572T2 (enExample) |
| TW (1) | TWI428130B (enExample) |
| UA (1) | UA101323C2 (enExample) |
| WO (1) | WO2008142463A2 (enExample) |
| ZA (1) | ZA200908283B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0700353A2 (en) * | 2007-05-18 | 2008-12-29 | Richter Gedeon Nyrt | Metabolites of (thio)carbamoyl-cyclohexane derivatives |
| US7875610B2 (en) * | 2007-12-03 | 2011-01-25 | Richter Gedeon Nyrt. | Pyrimidinyl-piperazines useful as D3/D2 receptor ligands |
| WO2009104739A1 (ja) * | 2008-02-21 | 2009-08-27 | 田辺三菱製薬株式会社 | 経口投与用固形製剤 |
| UA104869C2 (uk) | 2008-07-16 | 2014-03-25 | Ріхтер Гедеон Нірт. | Фармацевтичні композиції, що містять ліганди рецептора дофаміну |
| HU230067B1 (hu) | 2008-12-17 | 2015-06-29 | Richter Gedeon Nyrt | Új piperazin só és eljárás előállítására |
| HUP0800766A2 (en) | 2008-12-18 | 2010-11-29 | Richter Gedeon Vegyeszet | Process for the preparation of piperazine derivatives |
| HUP0800765A2 (en) | 2008-12-18 | 2010-11-29 | Richter Gedeon Nyrt | A new process for the preparation of piperazine derivatives and their hydrochloric salts |
| US9610274B2 (en) * | 2010-06-30 | 2017-04-04 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating bipolar disorder |
| WO2014031162A1 (en) | 2012-08-20 | 2014-02-27 | Forest Laboratories Holdings Limited | Crystalline form of carbamoyl-cyclohexane derivatives |
| US11274087B2 (en) | 2016-07-08 | 2022-03-15 | Richter Gedeon Nyrt. | Industrial process for the preparation of cariprazine |
| US11547707B2 (en) | 2019-04-10 | 2023-01-10 | Richter Gedeon Nyrt. | Carbamoyl cyclohexane derivatives for treating autism spectrum disorder |
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| BR0207832A (pt) * | 2001-02-27 | 2004-06-22 | Ortho Mcneil Pharm Inc | Compostos de carbamato para uso na prevenção ou tratamento de distúrbio bipolar |
| HU227534B1 (en) * | 2003-08-04 | 2011-08-29 | Richter Gedeon Nyrt | (thio)carbamoyl-cyclohexane derivatives, process for producing them and pharmaceutical compositions containing them |
| HUE033357T2 (en) | 2007-05-11 | 2017-11-28 | Richter Gedeon Nyrt | Crystalline form of carbamoylcyclohexane derivatives |
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2007
- 2007-05-24 HU HU0700370A patent/HUP0700370A2/hu unknown
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- 2008-05-19 ES ES08762655.2T patent/ES2397962T5/es active Active
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2009
- 2009-11-11 IL IL202048A patent/IL202048A/en active IP Right Grant
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2013
- 2013-01-25 CY CY20131100073T patent/CY1113566T1/el unknown
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