KR20150013803A - 광감제 및 키토산의 컨쥬게이트, 및 이의 용도 - Google Patents

광감제 및 키토산의 컨쥬게이트, 및 이의 용도 Download PDF

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Publication number
KR20150013803A
KR20150013803A KR1020147035218A KR20147035218A KR20150013803A KR 20150013803 A KR20150013803 A KR 20150013803A KR 1020147035218 A KR1020147035218 A KR 1020147035218A KR 20147035218 A KR20147035218 A KR 20147035218A KR 20150013803 A KR20150013803 A KR 20150013803A
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compound
cell
group
cells
molecule
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Ceased
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KR1020147035218A
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English (en)
Korean (ko)
Inventor
크리스티안 버그
앤덜스 하그세트
마르 마손
비베크 에스. 가와레
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피씨아이 바이오테크 에이에스
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Priority to KR1020207019532A priority Critical patent/KR102269861B1/ko
Publication of KR20150013803A publication Critical patent/KR20150013803A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/722Chitin, chitosan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/00272-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020147035218A 2012-05-15 2013-05-14 광감제 및 키토산의 컨쥬게이트, 및 이의 용도 Ceased KR20150013803A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020207019532A KR102269861B1 (ko) 2012-05-15 2013-05-14 광감제 및 키토산의 컨쥬게이트, 및 이의 용도

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1208548.6 2012-05-15
GBGB1208548.6A GB201208548D0 (en) 2012-05-15 2012-05-15 Compound and method
PCT/EP2013/059968 WO2013189663A1 (en) 2012-05-15 2013-05-14 Conjugate of a photosensitiser and chitosan and uses thereof

Related Child Applications (1)

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KR1020207019532A Division KR102269861B1 (ko) 2012-05-15 2013-05-14 광감제 및 키토산의 컨쥬게이트, 및 이의 용도

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KR20150013803A true KR20150013803A (ko) 2015-02-05

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KR1020147035218A Ceased KR20150013803A (ko) 2012-05-15 2013-05-14 광감제 및 키토산의 컨쥬게이트, 및 이의 용도

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US (1) US9901636B2 (enExample)
EP (1) EP2849791B1 (enExample)
JP (1) JP6456284B2 (enExample)
KR (2) KR102269861B1 (enExample)
CN (1) CN104780941B (enExample)
AU (1) AU2013279748B2 (enExample)
BR (1) BR112014028315B1 (enExample)
CA (1) CA2873259C (enExample)
DK (1) DK2849791T3 (enExample)
ES (1) ES2682762T3 (enExample)
GB (1) GB201208548D0 (enExample)
HR (1) HRP20181276T1 (enExample)
HU (1) HUE039725T2 (enExample)
IN (1) IN2014DN09418A (enExample)
MX (1) MX362237B (enExample)
NZ (1) NZ630582A (enExample)
PL (1) PL2849791T3 (enExample)
PT (1) PT2849791T (enExample)
RU (1) RU2675830C2 (enExample)
SG (1) SG11201407603YA (enExample)
SI (1) SI2849791T1 (enExample)
WO (1) WO2013189663A1 (enExample)
ZA (1) ZA201408406B (enExample)

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GB9905911D0 (en) 1999-03-15 1999-05-05 Photocure As Method
WO2015154832A1 (en) 2014-04-11 2015-10-15 Pci Biotech As Method of treating melanoma
AU2015308345B9 (en) * 2014-08-28 2020-12-24 Pci Biotech As Compound and method
CN104650259A (zh) * 2015-01-23 2015-05-27 广西大学 一种纳米孔壳聚糖四(4-磺酸基苯基)金属卟啉微球及其制备方法和使用方法
GB201503776D0 (en) 2015-03-05 2015-04-22 Pci Biotech As Compound and method
GB201511159D0 (en) 2015-06-24 2015-08-05 Univ Nottingham Controlled cell delivery vehicle and treatment of tumours
WO2017162918A1 (en) * 2016-03-22 2017-09-28 Åbo Akademi University Polysaccharide derivatives as optical brightening agents
KR20190013289A (ko) * 2017-08-01 2019-02-11 순천대학교 산학협력단 수용성 키토산을 포함하는 나노광증감제
GB201801169D0 (en) * 2018-01-24 2018-03-07 Pci Biotech As Method
CN108892743A (zh) * 2018-05-28 2018-11-27 南京工业大学 用于光动力抗菌的纳米光敏剂,其制备方法及应用
GB202101726D0 (en) 2021-02-08 2021-03-24 Pci Biotech As Method
CN115399328B (zh) * 2021-05-27 2024-03-22 中国科学院化学研究所 一种多糖基杀菌材料及其制备方法和应用
GB202115451D0 (en) 2021-10-27 2021-12-08 Pci Biotech As Method
CN117285662A (zh) * 2022-06-15 2023-12-26 南京仁为医药科技有限公司 一种壳聚糖双吡啶季铵盐及其制备方法
GB202301312D0 (en) 2023-01-30 2023-03-15 Pci Biotech As Method and product

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NO180167C (no) 1994-09-08 1997-02-26 Photocure As Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol
GB9905911D0 (en) * 1999-03-15 1999-05-05 Photocure As Method
US20020022032A1 (en) 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
GB0018527D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Composition
JP2002241307A (ja) * 2001-02-19 2002-08-28 Yasuhiko Tabata 光増感剤を含有する超音波治療用活性酸素発生剤
GB0121023D0 (en) 2001-08-30 2001-10-24 Norwegian Radium Hospital Res Compound
GB0415663D0 (en) 2004-07-13 2004-08-18 Psimei Pharmaceuticals Plc Compound
EP1888115A2 (en) 2005-05-16 2008-02-20 Universite De Geneve Compounds for photochemotherapy
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KR101250150B1 (ko) * 2010-10-29 2013-04-04 가톨릭대학교 산학협력단 광역학치료를 위한 고분자-광응답제 접합체 및 이의 제조방법

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Publication number Publication date
HRP20181276T1 (hr) 2018-11-16
IN2014DN09418A (enExample) 2015-07-17
SI2849791T1 (sl) 2018-10-30
CN104780941B (zh) 2019-01-15
AU2013279748A1 (en) 2014-11-20
ES2682762T3 (es) 2018-09-21
SG11201407603YA (en) 2014-12-30
WO2013189663A1 (en) 2013-12-27
MX362237B (es) 2019-01-09
GB201208548D0 (en) 2012-06-27
CA2873259A1 (en) 2013-12-27
RU2675830C2 (ru) 2018-12-25
NZ630582A (en) 2017-02-24
PT2849791T (pt) 2018-10-04
ZA201408406B (en) 2016-02-24
CN104780941A (zh) 2015-07-15
EP2849791A1 (en) 2015-03-25
KR102269861B1 (ko) 2021-06-28
RU2014150569A (ru) 2016-07-10
US9901636B2 (en) 2018-02-27
HK1203850A1 (en) 2015-11-06
AU2013279748B2 (en) 2018-08-02
EP2849791B1 (en) 2018-07-04
CA2873259C (en) 2021-08-03
JP6456284B2 (ja) 2019-01-23
DK2849791T3 (en) 2018-08-13
MX2014013516A (es) 2015-11-13
BR112014028315A2 (pt) 2017-10-24
US20150202293A1 (en) 2015-07-23
JP2015516496A (ja) 2015-06-11
KR20200085380A (ko) 2020-07-14
HUE039725T2 (hu) 2019-01-28
BR112014028315B1 (pt) 2022-02-22
PL2849791T3 (pl) 2019-03-29

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