NZ630582A - Conjugate of a photosensitiser and chitosan and uses thereof - Google Patents

Conjugate of a photosensitiser and chitosan and uses thereof

Info

Publication number
NZ630582A
NZ630582A NZ630582A NZ63058213A NZ630582A NZ 630582 A NZ630582 A NZ 630582A NZ 630582 A NZ630582 A NZ 630582A NZ 63058213 A NZ63058213 A NZ 63058213A NZ 630582 A NZ630582 A NZ 630582A
Authority
NZ
New Zealand
Prior art keywords
chitosan
photosensitiser
conjugate
novel
conjugates
Prior art date
Application number
NZ630582A
Other languages
English (en)
Inventor
Kristian Berg
Anders Høgset
Már Másson
Vivek S Gaware
Original Assignee
Pci Biotech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pci Biotech As filed Critical Pci Biotech As
Publication of NZ630582A publication Critical patent/NZ630582A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/722Chitin, chitosan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/00272-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ630582A 2012-05-15 2013-05-14 Conjugate of a photosensitiser and chitosan and uses thereof NZ630582A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1208548.6A GB201208548D0 (en) 2012-05-15 2012-05-15 Compound and method
PCT/EP2013/059968 WO2013189663A1 (en) 2012-05-15 2013-05-14 Conjugate of a photosensitiser and chitosan and uses thereof

Publications (1)

Publication Number Publication Date
NZ630582A true NZ630582A (en) 2017-02-24

Family

ID=46458880

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ630582A NZ630582A (en) 2012-05-15 2013-05-14 Conjugate of a photosensitiser and chitosan and uses thereof

Country Status (23)

Country Link
US (1) US9901636B2 (enExample)
EP (1) EP2849791B1 (enExample)
JP (1) JP6456284B2 (enExample)
KR (2) KR102269861B1 (enExample)
CN (1) CN104780941B (enExample)
AU (1) AU2013279748B2 (enExample)
BR (1) BR112014028315B1 (enExample)
CA (1) CA2873259C (enExample)
DK (1) DK2849791T3 (enExample)
ES (1) ES2682762T3 (enExample)
GB (1) GB201208548D0 (enExample)
HR (1) HRP20181276T1 (enExample)
HU (1) HUE039725T2 (enExample)
IN (1) IN2014DN09418A (enExample)
MX (1) MX362237B (enExample)
NZ (1) NZ630582A (enExample)
PL (1) PL2849791T3 (enExample)
PT (1) PT2849791T (enExample)
RU (1) RU2675830C2 (enExample)
SG (1) SG11201407603YA (enExample)
SI (1) SI2849791T1 (enExample)
WO (1) WO2013189663A1 (enExample)
ZA (1) ZA201408406B (enExample)

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GB9905911D0 (en) 1999-03-15 1999-05-05 Photocure As Method
EP3129045B1 (en) 2014-04-11 2022-03-02 PCI Biotech AS Method of treating melanoma
JP2017526371A (ja) * 2014-08-28 2017-09-14 ピーシーアイ バイオテック エイエス 化合物および方法
CN104650259A (zh) * 2015-01-23 2015-05-27 广西大学 一种纳米孔壳聚糖四(4-磺酸基苯基)金属卟啉微球及其制备方法和使用方法
GB201503776D0 (en) 2015-03-05 2015-04-22 Pci Biotech As Compound and method
GB201511159D0 (en) 2015-06-24 2015-08-05 Univ Nottingham Controlled cell delivery vehicle and treatment of tumours
CN108884638B (zh) * 2016-03-22 2021-08-31 奥布专科学院 作为光学增白剂的多糖衍生物
KR20190013289A (ko) * 2017-08-01 2019-02-11 순천대학교 산학협력단 수용성 키토산을 포함하는 나노광증감제
GB201801169D0 (en) 2018-01-24 2018-03-07 Pci Biotech As Method
CN108892743A (zh) * 2018-05-28 2018-11-27 南京工业大学 用于光动力抗菌的纳米光敏剂,其制备方法及应用
GB202101726D0 (en) 2021-02-08 2021-03-24 Pci Biotech As Method
CN115399328B (zh) * 2021-05-27 2024-03-22 中国科学院化学研究所 一种多糖基杀菌材料及其制备方法和应用
GB202115451D0 (en) 2021-10-27 2021-12-08 Pci Biotech As Method
CN117285662A (zh) * 2022-06-15 2023-12-26 南京仁为医药科技有限公司 一种壳聚糖双吡啶季铵盐及其制备方法
GB202301312D0 (en) 2023-01-30 2023-03-15 Pci Biotech As Method and product

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GB9905911D0 (en) * 1999-03-15 1999-05-05 Photocure As Method
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GB0018527D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Composition
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JP4287411B2 (ja) * 2005-07-01 2009-07-01 株式会社東芝 仮想メモリシステムおよび仮想記憶方法
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KR101035269B1 (ko) * 2007-04-23 2011-05-26 한국과학기술연구원 고분자 유도체-광감작제 복합체를 이용한 새로운 광역학치료제
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WO2009077908A1 (en) 2007-12-14 2009-06-25 University Of Lausanne Colloidal particle comprising multivalent cyclic anions
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JP5662431B2 (ja) 2009-06-12 2015-01-28 エラスムス・ユニヴァーシティ・メディカル・センター・ロッテルダム 癌の光線力学療法のための標的化されたナノフォトメディスン
GB0914287D0 (en) 2009-08-14 2009-09-30 Pci Biotech As Compositions
KR101228106B1 (ko) 2010-01-21 2013-02-01 광주과학기술원 피부투과도, 세포유입 및 종양전달성이 증가된 나노운반체
KR101250150B1 (ko) * 2010-10-29 2013-04-04 가톨릭대학교 산학협력단 광역학치료를 위한 고분자-광응답제 접합체 및 이의 제조방법

Also Published As

Publication number Publication date
CA2873259C (en) 2021-08-03
KR20200085380A (ko) 2020-07-14
EP2849791A1 (en) 2015-03-25
RU2675830C2 (ru) 2018-12-25
BR112014028315B1 (pt) 2022-02-22
BR112014028315A2 (pt) 2017-10-24
EP2849791B1 (en) 2018-07-04
KR20150013803A (ko) 2015-02-05
US9901636B2 (en) 2018-02-27
CN104780941A (zh) 2015-07-15
WO2013189663A1 (en) 2013-12-27
CN104780941B (zh) 2019-01-15
KR102269861B1 (ko) 2021-06-28
JP2015516496A (ja) 2015-06-11
SG11201407603YA (en) 2014-12-30
AU2013279748A1 (en) 2014-11-20
PL2849791T3 (pl) 2019-03-29
PT2849791T (pt) 2018-10-04
MX362237B (es) 2019-01-09
JP6456284B2 (ja) 2019-01-23
ES2682762T3 (es) 2018-09-21
HUE039725T2 (hu) 2019-01-28
ZA201408406B (en) 2016-02-24
MX2014013516A (es) 2015-11-13
GB201208548D0 (en) 2012-06-27
IN2014DN09418A (enExample) 2015-07-17
RU2014150569A (ru) 2016-07-10
US20150202293A1 (en) 2015-07-23
DK2849791T3 (en) 2018-08-13
SI2849791T1 (sl) 2018-10-30
HRP20181276T1 (hr) 2018-11-16
AU2013279748B2 (en) 2018-08-02
CA2873259A1 (en) 2013-12-27
HK1203850A1 (en) 2015-11-06

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